a16z Podcast - a16z Podcast: Produce or Perish! (What We Eat)

Episode Date: December 14, 2016

Nature is the ultimate complex system, of course — but with today’s technology, it’s now provided us with an “incredible toolkit” of different molecules that material scientists can treat li...ke Legos to make some really interesting products. One of those is a protective layer for fruits and vegetables that extends shelf life and freshness. Because all produce is seasonal, it’s perishable — so there’s a limited geographical radius around which it can travel… whether by land, sea, or air. How does this change what food we sell, buy, eat… taste? How does it affect smallholder farmers both in the United States and in the developing world — where there’s no real infrastructure, yet alone for a cold-storage supply chain? And finally, what are some of the most interesting advances in the interdisciplinary field of materials science right now and up next: Is it finally time for these “hard”ware companies to be more software-like? All this and more (and unfortunately, some puns too!) on this episode of the a16z Podcast with Apeel founder and CEO James Rogers and a16z partners Malinka Walaliyadde and Sonal Chokshi. Will tech reshape the food-map of the world? The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

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Starting point is 00:00:00 The content here is for informational purposes only, should not be taken as legal business, tax, or investment advice, or be used to evaluate any investment or security and is not directed at any investors or potential investors in any A16Z fund. For more details, please see A16Z.com slash disclosures. Hi everyone, welcome to the A6NZ podcast. Today's episode is with one of our newest portfolio companies, which is applying nanoscale material science to fruit and vegetables. In this episode, we cover everything from how that affects what we taste and what we see at the grocery store, to farming and both local and international food supply chains, to how nature, the ultimate complex system works. And then more generally, we talk about how material sciences advances are playing out differently today, thanks to a few interesting things. And just why we, okay, I heart material science so much. We have with us today, A6-S-N-Z partner Malinka Wali-A-Ladi and James Rogers, who is the CEO and founder of Appeal. Formerly Appeal Technology and now Appeal Sciences. And that's Appeal with AP-E-E-E-L, not A-P-P-E-A-L. We like our puns. Well, it's really appealing and interesting what you're working on, so I couldn't resist. I hope we have a fruitful discussion.
Starting point is 00:01:09 Oh, no, God, stop right there. The investment memo that I wrote up was full of puns. I actually spent extra time thinking about apples to apples to avocados to avocado. Yes, I did not. Okay, let's talk about the fact that the pitch, the graphs on their slide, this is what I noticed. We're color-coded by the fruits. And so, okay, we're giving a lot of insider knowledge. Let me just tell our audience what the hell we're talking about, which is that you guys work with food technology. And in particular, one of the first products that you guys have out is a protective layer. Actually, I'll let you describe what your product is. We use food to preserve food, which sounds really abstract. And so to make it more tangible, effectively what we do is we take uneaten plant material. So things like stems, leaves, grape skins, orange peels, banana leaves, whatever is available. We blend those things up and then from those blends, we extract very particular
Starting point is 00:02:01 subsets of molecules. When you say you blend those things up, it sounds like a smoothie. Yeah. You know, it's not half a banana and a quarter of a strawberry or something like that. We actually know down to the isomer what these materials are when we create these blends. We then extract those really particular subsets of materials. I turn them into powders so they're lightweight, they're local. cost to distribute. And then we ship them to wherever we'd like to use them. We reconstitute them
Starting point is 00:02:22 in liquid form. And we dip fresh produce into that solution. And we allow it to dry. So what, first of all, does that mean I'm going to be eating like a strawberry that's like covered in this weird material? What's actually happening is what we're doing basically is taking materials from inside of that strawberry, the structural building blocks, the components that give the produce its actual structure. We're extracting those and then we're reapplying them to the outside of the produce. And so the materials that we actually apply are imperceptible. So I wouldn't taste it. Yeah, you actually can't taste it. It actually tastes much closer to the fruit when it was actually picked originally. What it's really doing is providing a protective layer that preserves
Starting point is 00:03:01 its shelf life and its freshness. That's exactly right. I'm asking about strawberries in particular as an example because the one thing I know about strawberries apparently have the highest concentration of pesticides of any fruit. Like you have to like wash. it like three times. And I'm OCD, so I watch my strawberries like five times. So I get the disgusting layers off to make it fresh and healthy. Yeah, it's really tough. I mean, strawberries are in a really difficult position. And actually a lot of agriculture is this way in that the way that we grow food, the way that nature produces things is through a systems approach. It's got this huge complex system. And part of the system is growing things. And part of the system is breaking down things and
Starting point is 00:03:40 recycling them. And it's got this whole machinery that's built up. The problem is for us in commercial agriculture, we don't care so much about the breakdown. We don't really care about the system diversity. We just want to contain as many variables in that system as we possibly can. And so what you end up doing in things like strawberries in particular, really sensitive, delicate fruit is that even before you get started, you go out and you tarp the field and you hit it with something like methyl bromide or chloropichron or hot steam, which just carpet bomb. everything that's in the soil. And now you're able to plant your fruit, and so it won't be attacked by any of those things that were out there naturally.
Starting point is 00:04:20 But that leads to the ability of certain pests and pathogens to get into that system because there's no kind of natural defenses that are out there. So it's really kind of interesting, you know, by solving one problem, you create other problems. A long-winded way of saying there is, you know, significant amount of pesticide usage that's just required in order to get you fresh high quality produce to your table currently. The trick about what we're doing is that it's not some sort of synthetic material that nature's never seen before. We're just using the exact same building blocks that nature uses every single day. And we're simply repurposing them for a different application. So I want to say something that's probably
Starting point is 00:05:02 not very popular in this room, which is that sounds like a high class problem to me because I've been to countries where you actually don't get a lot of fruits and choice and what you eat. Like you actually can only get certain items certain times of year. And so it's certainly very useful. It's preserving food. But like what is the benefit overall? Like when you think of the food ecosystem as a whole, like what does it really do for us? So it's interesting, you know, because it's a high class problem. And indeed, you know, preserving fresh berries is is definitely a high class problem. You know, if the joke at, you know, at the retail level is that the berry consumer spends twice the number of dollars in the grocery store as a non-bary consumer. And so it, it, it,
Starting point is 00:05:41 According to Driscoll's, that's true. Wow. And so in that sense, yeah, absolutely, you can actually put numbers to it, preserving berries, is a high class problem. The interesting thing about that, though, is that perishability affects every single kind of produce on this planet. And that means that it's either feast or famine in most parts of the world, particularly if you only have a, if you're a smaller farmer, you only grow in one type of crop. So my example I always pick on is, you know, if you're a mango farmer in the developing world and you're... I love mangoes, by the way. It's my favorite thing.
Starting point is 00:06:12 I think if you're from South Asia, you have to love money. Yes, exactly. I love, and they're so seasonal. You can only add them at certain times a year. Really tricky. But anyways. So the problem with perishability is really that everything is seasonal and it's also perishable. And that means that if I'm growing a particular commodity in a portion of the world that does not have access to a market where I'm able to turn that commodity into money, then it doesn't even matter if I'm growing that food.
Starting point is 00:06:39 I'm not able to earn economic returns for my labor. And so what ends up happening is you end up having nature doing its thing, growing all of this produce that's inherently valuable. But because of the perishability, because of the inability to get that produce from the place that it's produced to the market where someone's actually willing to pay for it, you return none of the economic value for your labor. So it's all about market access. So in the case of mangoes, if I'm a farmer in India who's growing mangoes, and I am a consumer in the U.S. who wants those mangoes, currently, I probably really can't get them. It comes really down to transportability and transportation costs. So for example, in the case of avocados, you know, the price of shipping a box of avocados to China is more expensive than the box of avocados itself because because of perishability, you have to air freight them in. It's not just the distance and the cost, but because of the perishability, it requires a faster method. And you can actually, you can look at it in really interesting ways.
Starting point is 00:07:43 I mean, the way I always think about the world is that, again, I keep going back to this, all produce is seasonal and it's also perishable. And so you can look around the world around where produce is available at different times of year, where it's able to be grown. And then you know the overall shelf life of that commodity. And you know how fast the boat can move. You know how fast the plane can fly. And so you can draw basically, you know, a circle around those production regions and show where produce is available, basically at what cost throughout the year. What we're able to do is dramatically extend the shelf life of that produce, which dramatically expands the overall radius of availability of fresh produce, which opens up new export markets for customers. That actually goes in both directions, too.
Starting point is 00:08:27 If you're a grower in California or the Midwest, you can now set. to China, like your avocados. Oh, yeah. But on the flip side, if you are a grower in India who has avocados, you can now sell them to California or the Midwest or anywhere else. You're totally correct that this absolutely goes both ways. And it's actually really fortunate that it goes both ways because if you're a smaller farmer out in the middle of nowhere and you've got a thousand mangoes and your neighbor's got
Starting point is 00:08:54 a thousand mangoes and your other neighbor's got a thousand mangoes, you can't sell a mango to your neighbor to save your life. Just a race at the bottom because you can't, you have no margins. And they rot. And they just rot. And that's the, it's, you know, it's said to me once for fresh produce, the tyranny of time. And that really resonated with me because if you think about the position a smaller farmer is in when a trader comes to them, that trader has the best leverage in the world because they know that they can just sit outside the farm until the mangoes rot and then say, well, you either sell them to me now or, or. sorry, I'm leaving. And so the smallholder farmers often left in a situation to say, well,
Starting point is 00:09:32 I can either earn two shillings per mango or nothing. And what we've found in talking to small hundred farmers is that if you can extend the shelf life of a mango by an extra week, they can earn an extra three to five shillings per mango. So it just by, I mean, it's amazing, right? You think about being able to just by preserving produce an extra week, be able to earn two to three times more for that exact same commodity, that's a dramatic improvement in the amount of economic value those small holders are able to capture. So, you know, a few times you've mentioned small farmers. Let's talk about the economics of farming in general and produce and food. So people talk about big food of the capital B and a capital F. You know, I know there's a lot of politics around that
Starting point is 00:10:15 topic, but politics aside, what does the ecosystem for farm and food production look like? There's small farms, there's middlemen, there's big farms. Like, what's the, what's the landscape? Yeah, I mean, And generally speaking, right, there's producers, you know, which is a really a large number of disaggregated relatively small farms. There's some huge farming operations, but a bunch of really disaggregated small farms. And then there's a relatively concentrated number of grower shippers that typically grow some portion of the crop that they're shipping. But then they aggregate or buy from a bunch of those disaggregated growers. then there's the, you know, growers shippers who are handling most of the transportation,
Starting point is 00:10:55 and then there's retailers, basically. That's going to be food service channel or just a general retailer, and then there's really the end consumer. There's some kind of side alleys in there and kind of different niches, but that's kind of the general organization. The problem with some of these, they just don't have the electricity, you know, whatever infrastructure, to support coal storage.
Starting point is 00:11:14 The way you extend the shelf life of fruit is very cold storage. I'm super happy you brought that up, Malika, because if you look at spoilage rates in the United States and, you know, the numbers are kind of all over the place, but they're between a third and a half of what we're growing. Holy shit. That's a lot of bad food going bad. Well, and it's particularly ridiculous when you consider the amount of resources that go into producing that food, right? You know, the numbers are around 80% of freshwater going into irrigation, you know, all of the pesticide usage that ends up, you know, running into the water streams that ends, that's, you know, putting pesticides on fruit that we're not even eating. all the human capital that goes into it,
Starting point is 00:11:49 all the fertilizer, all this stuff, and then ultimately a massive, massive amount of it's ending up in a landfill. And the funny thing about that is actually horribly unfunny is that that's in the U.S. We've got this incredible technology and incredible supply chain.
Starting point is 00:12:04 And the way that we've been able to get down to a third or 40% of our produce being thrown away is that we've been able to use refrigeration. We've able to use low temperature technology to basically slow everything, down inside the fruit. And that works, that's work that's gotten us to about, you know, throwing away a third, if you call that working. Now, so you start talking about trying to be
Starting point is 00:12:26 able to reduce losses, which can be, you know, 80, 90 percent of a harvest in the developing world. If you want to just piggyback off what we've done in the, in the quote unquote, developed world, you're trying to say, oh, well, everyone should just implement a cold chain. Well, that's really hard to tell a farmer to do in the developing world where there's hardly roads, let alone an electricity grid, let alone the capital equipment necessary to do the refrigeration. And so I often think of it as distributing, you know, refrigerators in a packet to treat their mangoes and get an extra 10 or 15 days of shelf life out of those without needing to do all the infrastructure development necessary. I love this theme. We, you know, did a podcast recently on drones. I was literally thinking the same
Starting point is 00:13:05 thing. And it is about how certain technologies can help you leapfrog the lack of infrastructure and essentially create this gonzo infrastructure essentially. And it's interesting. It plays out from both mobile, where you have entire countries leapfrogging existing PC infrastructure to go to mobile straight and be mobile first. In this case, like in the case of Zipline and drones and Rwanda, it's literally leapfrogging that there's a lack of roads and medical infrastructure. I literally was thinking on the same lines, which is using technology to compensate for the lack of traditional infrastructure. With Zipline, you're having them drone deliver medical supplies to compensate for the fact that they didn't have roads and medical infrastructure. You guys are
Starting point is 00:13:44 compensating with your technology for the fact that they don't have, you know, electricity, coal storage infrastructure. You mentioned mobile. It actually does, does all link together. It does, but it's fascinating that you use the word compensate because, yes, technically it is a sort of compensation, but I think the interesting thread to me is that it's actually an opportunity for an entirely new system that bypasses existing systems. It's actually a way to go outside.
Starting point is 00:14:04 When you think of like the full stack startup, I mean, not to get all crazy riffy, the thing that's really interesting that makes companies like Lyft and Uber work versus the traditional taxi services companies, according to Christensen's full stack, you know, startup thesis is that you're essentially bypassing existing systems in order to do it. So it's just a really fascinating theme in general when I think about how innovation happens. Oh yeah. I mean, that's exactly how I think about it as well. One of the ways I look at our product as well is infrastructure and a packet. You've got really poor roads. And now you're able to get that produce a certain distance before it goes bad. Well, if you double the shelf life of that produce,
Starting point is 00:14:36 it's effectively like doubling the rate that you're able to travel on that road. If you kind of think about it that way. And essentially opening up entirely new ways. of competing with people who have an entrenched position in existing infrastructure. Absolutely. And the other, I think, interesting point around that is what we've done in the United States is that we've built up these supply chains around the intrinsic constraints of the piece of produce. And this whole supply chain has been established, just understanding this is the limitation
Starting point is 00:15:04 of that piece of produce. You show up in Nigeria and you give somebody a packet of material that's able to make their tomato last twice as long. they're not going, how does this affect the temperature that I'm supposed to store my tomatoes during cold storage? They're not locked into that existing supply chain. And you're actually building from scratch as opposed to trying to wedge into an existing supply chain. So although it's difficult and challenging for particular reasons to deliver these technologies into developing countries, the white space or the opportunities are actually really, I think, an interesting kind of proving ground for what the ultimate power of the technology really can be.
Starting point is 00:15:41 I agree. And it's redefining technology. to me in an interesting way because when I think of the typical cold chain, I remember anecdotes from companies that were doing like thin film electronics and they would do like these sort of thin film disposable sensors as a way of putting really cheap RFID tags in order to tag the status of where it is in the supply chain and keep a certain temperature level and be able to monitor it continuously. And there's all these interesting, probably very useful, complicated technologies in the existing system. But what you're essentially doing is bypassing that with an entirely different, very
Starting point is 00:16:12 natural form of technology, which brings me to my next question, which is, what is the technology in the, quote, traditional or non-traditional sense that we're talking about here? Because it's kind of interesting. Like, you're essentially describing shredded plant parts. I think there's just an important distinction to be made in that classically, the technologies that we employ in agriculture, I think, are what I would, so I've kind of gone through this kind of mental exercise of what is a chemical and what is a molecule? That's a really interesting mental exercise. Yeah, right. Well, for I guess nerds, I guess. Why does the difference between a chemical and a molecule matter?
Starting point is 00:16:47 And this is my definition. But what I've landed on is, you know, for millions and millions of years, nature has used the same building blocks and it's just basically broken them down and recycled them into different forms. Very efficient thing for nature. She him it to do. An incredibly efficient thing. It's actually, you know, one of the only, you know, non-zero-sum games that I can really think of. I think it's beautiful and elegant the way that's been put together. but it's done pretty damn well without us for millions and millions of years. And then we came along and said, oh, nature, you've got these beautiful, well thought out systems in place. And what we're going to do is we're going to, we see the mechanism that you're using to do that. We're going to develop a new chemistry or a new molecule that's going to interfere with that particular machinery. The problem is that those processes that we generally interfere
Starting point is 00:17:33 with are really valuable processes. That's why they've stuck around for so long. And so they're used by many, many, many different types of life forms. And so it's incredibly challenging to poison one bug without poisoning every single bug that's out there, even the good ones. What nature's done is not generate, you know, kind of a poison to kill things. It's used the exact same molecules. It's just combined them in different ways to form different structures. And those structures generally provide protection from the external environment,
Starting point is 00:18:04 whether it be the scales on reptiles or the, you know, the skin on the leaf of a, of a plant. It's like a whole new form of combinatorial innovation. If that's what you're saying in Silicon Valley, then that's exactly what it is. I mean, in a way, there's a lot that goes into it. And empirically, actually, like, this is not a new idea what we're doing, right? Monks discovered in the Middle Ages that you were able to dip apples and beeswax and they would last throughout the winter.
Starting point is 00:18:30 Those are pretty incredible innovation at the time, especially considering lack of access to refrigeration. The same thing is true of beauty products, like being able to layer on layers of oils, or it's the same kind of thing with skin and preservation, because skin is perishable. Skin is very perishable. Actually, probably the number one question I get is, can I use this on my skin? I was about to say, when I saw your pitch, I was like, my mind immediately jumped into all
Starting point is 00:18:52 kinds of makeup products. Yeah, yeah. It's a really interesting future product line. Nature has provided us this incredible toolkit of different molecules that are available to us, and that us as material scientists are in a fortunate position now with today's technology to be able to isolate those materials from nature, look at them as if they were a Lego, and say, what would this be useful for?
Starting point is 00:19:16 And if I combine it with this other Lego and I let these things dry together, will they form a structure that could give me some really interesting properties? What are some of that? I mean, when you say that that way, it's a beautiful, a simpler explanation of what you're doing,
Starting point is 00:19:30 but actually what you're doing is actually pretty complex and complicated. It requires a lot of hard science. What are some of the challenges you have to overcome to be able to create those Legos and building by, or combinatorial innovation, as I would call it.
Starting point is 00:19:40 So for me to be able to sit here and abstract to the 30,000-foot level of analogy of Legos, I have to have a team of 62 very, very talented individuals composed of, you know, over 50 scientists, and 15 of those are PhD scientists. All in material science or different? Across disciplines. Okay. Chemistry, biochemistry, material science, chemical engineering, mechanical engineering. So across a wide range of disciplines.
Starting point is 00:20:07 and it actually requires each of those disciplines because one discipline is looking at how do we extract these materials, how do we purify these materials, which is one discipline, how do we take and confirm what these materials are, which is analytical chemistry? How do we then combine these things in different ways to form interesting structures? That's material science. How do we analyze these things? That's more than the physics realm. How do we have enzymes make these things for us?
Starting point is 00:20:31 That's biochemistry. I'm going to come work for you. You should definitely, it's really incredible. but what we've been able to do basically is rally this group of incredibly talented people around this core focus of leverage nature's operating system to solve problems that nature's solved before, basically by just blatantly copying what nature's doing. A lot of people sometimes I feel they overuse that analogy of an operating system, but I think in this case, it really applies. I mean, there is no other way to describe it. Well, for us in the physical realm, like nature's operating system are the laws of physics, and we, We just want to use that system, understand as much as we can, and then take pieces and let the operating system operate on them.
Starting point is 00:21:14 It feels like a different type of X-ray vision, where instead of just looking out the object and seeing, okay, that's a water bottle, knowing down to the molecule what it's made out of, why it has the properties it has, and how you could impact those properties by changing what the water bottle is made out of. It's not unlike how artists or photographers see the world differently when they paint or capture it on film. You just look at scenes very differently because you bring your craft at a very deep x-ray level. That's cool. We've got some materials artists. Yeah, it's very artistic to me. At the end of the day, what you're doing is super interesting. What are some of the other challenges?
Starting point is 00:21:47 I think it's iteration cycle, frankly, when it really comes down to it. I love programming computers because I'll write some code and I'll get a debug error. It says you did something wrong. You need to fix it. You know, the challenge in material science, you know, I'm just broadly speaking about material science here, is when you want to hit compile, it might mean something. six years of PhD work to compile the system that you might get one data set out of. And that iteration time really kills a lot of, I think, companies that are looking at getting
Starting point is 00:22:16 into materials-based company. How do you guys overcome that? I mean, you can't bypass it altogether. So a number of members of my team, you know, spent their PhD basically learning different techniques, technique development to basically access new understanding of some fundamental set of molecules. And so I think at our core, we have this kind of respect for not just using off-the-shelf technology to get general information, but really committing to understanding and learning a new technique or developing a new piece of equipment that can help speed up some of those iteration
Starting point is 00:22:49 cycles and material science. If you come by and visit our office, you'll see a large number of systems, analysis systems that we've built ourselves, that we've had to make the investment of time and money in that you would say, well, oh, no, no, no, you just need to keep hitting the fence, keep it in the fence. But when you're just hitting the fence and you don't have that feedback mechanism, then you can't tighten that loop, you lose the iteration. And then when you lose the iteration,
Starting point is 00:23:13 your probability success drops, plummets dramatically. So we've really made the investment in developing our own tools for characterizing these systems. So when you have that infrastructure for characterization or rapid prototyping, do you then make a tradeoff in your ability to then scale things? Because then you're not
Starting point is 00:23:29 using existing scaling things. I'm thinking of the analogy of semiconductors. And when people use to prototype custom chips versus going to a major fab. So I think that this is, we're at a really incredible time in history right now where you don't have to do that for most of this stuff you don't have to do that anymore because you can buy an Arduino unit for $12 and you can program what you used to have to solder a PCB board to do. Yeah. This is true in the material science of the food that you're working on.
Starting point is 00:23:56 For us, our entire office runs on Raspberry Pies and Arduino units that control controllers to measure different stuff. And the great thing about that is they are scalable because you just go buy another $40 computer that has a wireless card built into it that you communicate from halfway around the world, hook a couple custom built peripherals into that and you've scaled that system. So I think I would have agreed with you, you know, five, six years ago. Yeah. But with basically the advent of, frankly, the Arduino unit, we've really been able to scale this. I mean, and 3D printing. So, I mean, all of our time lapse systems are built with 3D printed components. Time-lap system?
Starting point is 00:24:34 It allows us to monitor the physical aging of fresh produce as a function of time. This is like super nerdy if we're going to geek out. Let's geek out. I spent a lot of my PhD work using transmission electron microscopy, tomography, to view things on really, really short length scales on nanometer length scales and really look at things in really fine detail. And the time lapse photography for us, for me, feels like a different kind of microscope that allows us to kind of view the world without time in terms of produce aging.
Starting point is 00:25:02 which really has led to some really incredible realizations about the physical aging process of fresh produce that's led to some really interesting developments at the company. You're literally compressing and adding an entire new dimension to your view because of the cheapness of being able to do 3D printing and all the other things. We would not have been able to do this more than eight years ago probably. I started in material science as well and I eventually moved on to more to more of the software because of the problem that you just mentioned, which is it's hard to. iterate. And I always thought that material science was sort of confined to R&D. There was a really good time for material science. I think a while ago with semiconductors, but I thought today it's mainly R&D. But I think because of some of the things you just mentioned, it's becoming possible to build a company based off a material science today more and more. Yeah, where it's not just like a tool or a future, but it is a, it is a core of a product. And I think the most exciting things in material science in general are things like flexible electronics, the future of that. I mean, to me, all these things are interconnected. Because the thing that held a lot of this innovation back before in the past was that there was a lack of supply chain for materials or the ability for different groups to work together or systems to rapidly prototype and then figure out to scale. And when you have all these different companies now coming into the space, just material science being taken more seriously as a core enabler for new types of tech, it's kind of phenomenal. Well, see, the funny thing to me is material science has been fundamental to us as a species.
Starting point is 00:26:29 Look at how we've defined our ages. a stone age, the bronze age, the iron age, steel age, right, silicon age. We define our development as a species by what material set we have available to us. I don't think it's that surprising that material science is becoming really interesting again because, you know, I view material science is bridging the gap between what's available and what's useful. How can you combine what's available to give you something that's useful and give you some new set of properties that enable some new advancement. The fruits are almost inconceivable
Starting point is 00:27:05 of material science innovations. I mean, think about if someone... Wait, you're saying fruit in an analogy sense, not like the actual literal fruits. Okay, let's be clear. You know what, actually, in this sense, it could be... Exactly.
Starting point is 00:27:16 It could be figurative or literal in this case for once. Imagine you're living in the society today and you event steel. You're... It's everywhere. It's everywhere on this planet. And so although the opportunities for games, in material science are just, I think, unfathomable almost.
Starting point is 00:27:33 It's incredibly difficult to do because material science is generally, or it's such an interdisciplinary field. That's exactly what I love about it so much. If I could go back and do school all over, I would do material science in a heartbeat. The challenge is you can do so many different things in materials. You can be doing the chemistry. You can be doing the characterization.
Starting point is 00:27:50 You can be doing the measurement. You can do the property stuff. You can do structural. You can do so many different things. And I used to say, I don't care how you make it. I just need a little, have you sure. show me the structure on paper, and I can tell you what it's useful for. But that's a big problem, right?
Starting point is 00:28:04 When you start talking about supply chain and building a business, okay, great. My skill set is around knowing what molecules can do and how to characterize them. I have no idea generally how to make them. And so without being able to connect those skill sets, people who know what to do with them and the people who know how to make them and then manufacture at scale and then, you know, do all this other stuff, is really difficult to come together. It's still a very hard problem. I wouldn't disagree.
Starting point is 00:28:29 in general, what are some of the interesting things you think are happening? Because I feel like people talk a lot about materials like graphene and what are the things that are happening in the industry that are high level interesting to you in that space. I would probably say probably the main breakthrough that will change a ton of technologies all across is battery technology. Yeah. Right. As if we can get higher storage, lighter, longer lasting batteries, that will change a lot, right? It will change everything from drones to VR to like literally every industry. But that, it's unclear if there will be a problem.
Starting point is 00:28:59 private company innovation or if that will be created out of a government lab somewhere. Right. One of the things that's really interesting about material science is unlike a lot of the other disciplines, maybe because it is cross-disciplinary, it is the one where I still think a lot of government-led innovation funding is the most important because they are the heads, they're
Starting point is 00:29:15 the most interested in really thinking of the next generation of materials. Well, and they're training the people that are going to do the work. Yeah. Right. I mean, all of our team, I mean, we couldn't have hired straight out of undergrad and test them to do what they do for us now. I mean, they needed the training. that came from government-supported programs
Starting point is 00:29:31 to do the core fundamental science that underlies what we're doing. For me, I think the part that I really get excited about is in the field of additive manufacturing. I mean, I look at a 3D printer now and we use them in our office and we're extruding a thermoplastic elastomer out of a heated nozzle
Starting point is 00:29:49 and we're just basically making a structure and letting it, melting it and letting it dry. And I look at that and go, wow, who's going to develop the HP of 3D printing with the different inks that are all from material science understanding that allows you to print a fully
Starting point is 00:30:06 functional device. We don't do that now, and maybe with a combination of laser centering, some other stuff. But if you start thinking about combining chemistry and mechanical engineering and robotics, which give you the 3D printing with material science, which gives you the ink,
Starting point is 00:30:24 I think the opportunities for doing, you know, local manufacturing or just kind of incomprehensible. The great example I think of is this initiative, a lot of people from NASA to Autodesk that I've been working on, which is bringing 3D printing to be able to like recreate entire new structures in space so that you can actually build what you need. That's like local manufacturing on crack.
Starting point is 00:30:42 Yeah, no, exactly. And I think it's, I mean, I think in the future you're going to have a fancy 3D printer in your home and how wealthy you are is going to be what type of 3D printer you have. If you're really wealthy, you can print the latest and greatest iPhone. and if you're not so wealthy, maybe you can only print, you know, shoes or something like that. Well, let's close on talking about your, our vision for the future of food. What do you guys see the future grocery stores looking like? I mean, does this change the, what shows up on our shelves?
Starting point is 00:31:10 That's actually the thing that probably gets to be most excited. You know, there's a reason that if you, you know, held up a dozen different kinds of produce, that most people could name those common dozen kinds of produce. But if you think about the genetic diversity that exists on this planet, There are millions and millions of different kinds of produce. The reason that you're not able to identify them is that you don't live in a region in the world in which they're grown or you don't live in a region to which those products are able to be imported into. And so, you know, when I think about what happens is, you know, what plant breeders do basically is when they're breeding a new crop,
Starting point is 00:31:47 they're looking down the list and number one thing on their list is transportability. And taste, nutrition is like level 12 or 13 on the list. you know, it takes really significant investment for big companies to be developing breeding programs. And those breeding cycles are like eight years long. And so you need to do super, like massive investment to come up with these new varieties. And so one of the divisions of the future that I get really excited about is the opportunity to extend the shelf life of a crop so that smaller produce variety can make it into it, make it into a grocery store. And this is the same value proposition for a small organic grower in the United States as it is for. for a smallholder farmer in the developing world. Same thing with an organic farmer in the U.S.
Starting point is 00:32:28 and one crop that we worked on that we never thought we'd work on are called finger limes. And check them out if you haven't picked these things up in the grocery. They're natively from Australia, but they were brought into the United States about eight years ago now. It's good the U.S. government
Starting point is 00:32:43 didn't make them record a video to apologize for bringing them in. Sorry, I didn't make that joke. Do you guys remember what happened with Johnny Depp and his ex-wife now and bringing their dog to Australia? But anyway, go on. That's pretty great.
Starting point is 00:32:54 Delicious with shellfish. Yeah. Oh, yeah. Oh, yeah. So they're really interesting. They're actually another branch of citrus. But you cut them open and they look like caviar pearls. And each of those little pearls has a citrus flavor to it.
Starting point is 00:33:06 I know that my finger limes, caviar limes, or cocktail limes. Okay. But they're really these incredible little citrus fruit. And the challenge with them is, you know, they brought them in the U.S. They grow a bunch of them. But the shelf life of these things is like five days maybe. A supply chain that only lasts five days doesn't get you into very much. many stores. It's just not really commercially viable. And so we've been able to extend the shelf
Starting point is 00:33:28 life out to like 25 days. What's normal in terms like, so I grew a part of my life in Sri Lanka. I mean, what's normal here, apples, bananas, berries is actually really rare there. And what's normal there is like papaya, mangoose, Rambutan, all these things that people have never heard of. And some of them are just incredibly delicious and more so than anything you'd find here. You just don't get access to them here. So like in some future world, you can move that around. You can move that around. and what you'll eat is not the most transportable food. It's just the best fruit. Right, exactly.
Starting point is 00:33:56 It's no longer constrained by only time or transport. Exactly. And not just the best type of fruit, but the best grower, right? And fruit that's grown in regions that, for example, strawberries that's grown in Watsonville and bread in Watsonville. And now you're transporting that down into Mexico to grow. That fruit was optimized for growth in Watsonville, right? That genetic variety might not be the best one in Mexico. but because doing a breeding program in a bunch of disparate places to match a local geography,
Starting point is 00:34:26 it's so cost prohibitive, you just go with that. Produce that's better suited to the growing environment that it's actually in. You can actually improve yields relative to what they'd be if they were bred in another environment. And it just allows new entry points, like you said, for all different types of new players. It's democratizing access on both ends. And this is a theme that I love. But the other thing that, you know, earlier you mentioned how you can do a map of all the fruit around the world and map the times and their perishability.
Starting point is 00:34:49 And it reminded me the image that popped into my mind is this map that makes this rounds on Twitter that's really popular of countries organized by the most popular social network. It's essentially a way of showing this dissolution of borders and movement through technology. And what I love about what you're describing is you can now essentially remake that map
Starting point is 00:35:07 that you described of all this produce and by perishable life, by shelf life and location, and essentially just move it all over and make time not matter. Yeah, or not matter as much. Or not matter as much. I don't want to exaggerate it, but that's a pretty big effing deal. James, thank you for joining the A6 and Z podcast.
Starting point is 00:35:26 Thank you so much for having me. Thanks.

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