Change Your Brain Every Day - Pain Relievers: Ones to Choose & Lose
Episode Date: March 7, 2018A recent study has linked Acetaminophen (Tylenol) with autism in babies when taken during pregnancy. In this episode of The Brain Warrior’s Way Podcast, Dr. Daniel Amen and Tana Amen discuss which p...ain relievers are the safest and have the least side effects, and which ones should be avoided.
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Welcome to the Brain Warriors Way podcast.
I'm Dr. Daniel Amen.
And I'm Tana Amen.
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You know, we've just learned so much great information
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helping people have better brains and better lives.
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Now, this podcast is gonna be a little different, but it's based on a research study that came
out recently on acetaminophen or Tylenol and autism.
Now I've stayed away from acetaminophen for a number of years.
Yeah, you told me that. Because when I wrote my book, Preventing Alzheimer's, with Rod Shankle,
we found that people who use Tylenol on a regular basis
got Alzheimer's disease two and a half years earlier than the general population.
And people who used Advil as their pain medication
actually got Alzheimer's disease two and a half years later.
So why is that?
Than the general population.
Well, being a nurse who worked in a hospital, you know one of the most devastating kinds of overdoses is Tylenol.
Because of the liver.
Because it damages your liver. So if you take something on a regular basis that damages
your liver, what happens is your body doesn't properly detoxify itself and toxins build up.
So let me read the study. So it's the most commonly used pain and fever medication during pregnancy. Previously, a positive ecological correlation between acetaminophen use and autistic spectrum
disorders was reported, but evidence from larger studies based on prospective data,
that means looking at it in the future, not the past, was lacking. So they followed
64,322 children and mothers enrolled in the Danish national birth cohort from 1996 to 2002.
So the Danes and the Finns are actually really great, Swedes too, at keeping health data
on their populations.
So they checked for an average of 12.7 years to investigate whether acetaminophen use in
pregnancy was associated with an increased risk of autistic spectrum disorders in the
offspring.
The information on acetaminophen use was collected prospectively
from three computer-assisted telephone interviews.
They used records from the Danish hospital and psychiatric registries
to identify the diagnoses of autistic spectrum disorders.
At the end of follow-up,
so of the 64,000 kids a thousand twenty seven were diagnosed
with autistic spectrum disorders they found that 31% of kids were also
hyperactive more than 50% of women reported ever using acetaminophen in
pregnancy and what they found the women who use of women reported ever using acetaminophen in pregnancy.
And what they found, the women who used acetaminophen
had a significantly higher number of autistic spectral hits.
Oh, interesting.
So I'm gonna push back for one second
because that makes sense and it's very interesting.
But when you said, when you talked about Alzheimer's
with acetaminophen versus Advil or ibuprofen. The only thing I wanted to point out there is that
we also know that that decreases gut bacteria, which is bad for your brain and can long-term
increase inflammation, which is also bad for your brain. So we've got to be paying attention
sort of to all of it and how much you use. Now, we're all grateful for medication when you need
it. Just be careful about chronic use of any of these, right? Because they have side effects. So, you know, if you need
to take it, take it when you need to take it, but just know that there are side effects to chronically
using a lot of things. Well, and we're not huge fans of non-steroidal anti-inflammatories because
they can really affect your gut.
I just said that.
In a negative way. Yeah, no, I heard that. But it's also an anti-inflammatory.
Right.
So the anti-inflammatory. So if I had a choice, which one would I take? I'd take the non-steroidal
anti-inflammatories. And like I saw a woman last week who has the periods from hell where she cramps, she bleeds,
she's in a lot of pain, and she uses a fair amount of Advil.
Would I rather, especially because she wants to get pregnant, would I rather have her take
Advil or Tylenol?
And I'd rather have her take Advil and take probiotics along with it to help
rebuild her gut, but then also find out, well, why do you have heavy periods?
Maybe it's because she has estrogen dominance.
Or fibroid tumors.
But just be aware that long-term, it'll actually increase inflammation if you break down your
gut barrier, because that's what can happen. Well, I think this is just so important to be thinking about why the rise in autism.
So when I was a Child's Country Fellow from 1985 to 1987, we hardly talked about this
issue.
You know, it was like 1 in 10,000 kids.
And even though Asperger's syndrome, which is one of the autistic spectrum disorders,
was described in 1943, there just weren't that many. But beginning in the early 90s, it began to skyrocket.
Right.
And some people think it's associated with vaccines the the evidence
not clear on that at all it's not clear that it's not so that's important but i think it's a gene
toxin epigenetic interaction so that there's some toxin in the environment that is turning on these genes that make people vulnerable to autism.
And a number of my very learned friends think it's acetaminophen.
Is that, remember, well you may not remember, but in the 80, there was something called Rye syndrome that happened from aspirin.
Right.
So they stopped giving children aspirin.
And they started giving.
And they started giving them acetaminophen.
And we saw this significant rise.
Now, I know it's more complicated than that.
But according to some studies, this increases the risk by as much as 40 or 60%.
Wow, that's huge.
It's huge. And I'm sure it's not the only answer. I think it's also kids who live around
toxic dumps have a higher incidence of autism. We are, and you and I knew this when I was writing
Memory Rescue, and I was doing the toxin chapter and I had you
download this app Think Dirty and had you scan all of your personal products.
Think Dirty is an app that lets you scan your personal products to see what are the endocrine
disruptors in it, the toxins in it.
So is this primarily for pregnant women taking Advil or could it also apply to young
children taking Tylenol? Or can it also apply to if you give your children, young children
Tylenol, can it do something at that point?
I think it's mostly pregnant women is the study we're actually talking about.
When the fetus develop.
But anything that disrupts liver function or gut health,
we have to be thinking of other things to do.
Right.
So that, and one of the things I've never understood, ever,
especially when we've got, you know,
a society of kids who have such terrible ADD and other problems,
why are we putting red dye in all of their children's medicines?
What is that?
So it's pretty.
That's the dumbest thing.
So it tastes like cherry, although the taste has nothing to do with the red dye.
It is so dumb.
You know, that's a whole other thing, the artificial flavoring.
Well, and we have to be serious about this.
Having treated so many children who have autism, it devastates families.
Oh, it does.
It devastates families.
There's a high incidence of divorce because I just finished reading a book.
It was actually a novel.
So it's fictional, but she pegged what happens in an autistic family.
The book is called House Rules by Jodi Picoult.
And it's a wonderful book if you want to learn about the emotional impact of autism.
And TACA is a great organization.
Talk about curing autism.
TACA.
She's amazing.
Her story is amazing. TACA-C-A, talkanow.org.
But we want you to be thinking about, if you're thinking of having babies, don't use Tylenol.
And make sure your body is as clean as possible. One of the things I said this week in the lecture that a number of people came up to me
was about epigenetics
and how your habits turn on or off certain genes
that make illness more or less likely in you,
but also they affect your eggs and your sperm.
So in you, but also in generations of you.
My daughter, Caitlin, our daughter, Caitlin, is pregnant with her third child, and this time it's a girl, and everybody's excited, and we're getting ready for the shower.
But when Haven is born, Haven will be born with all of the eggs she'll ever have. And so Caitlin's behavior is impacting Haven's health, but also Haven's baby's health.
So there's a whole area based on that of medicine that I think is just fantastic.
And it's just growing like crazy.
It's preconception medicine.
So rather than, because, you know, sadly, as you know,
there should be a warning label on bottles of tequila may cause pregnancy. So it's just the
way it goes for so many women. They find out that they're pregnant after, you know, partying,
or they've been partying, or they've been out on vacation and drinking, and they find out they're
pregnant, and they've been drinking, right? They've not been thinking about pregnancy.
And then all of a sudden they clean up.
Now that's good.
We want you to clean up whatever you've been doing if you get pregnant all of a sudden.
But what really what a lot of people are beginning to realize is it's really a better idea if
you really get clean before you actually think about getting pregnant.
So clean your body up, really get yourself-
Like for six months.
Or a year.
So what preconception medicine does...
But so many babies are not planned.
Right.
So what preconception medicine does, because infertility is just out of control now.
It's out of control.
What preconception medicine does is helps women start thinking about,
when do I really want to have a baby?
Or for women who really know they want to have a baby, let's actually plan this out. And then they also help women start thinking about
this whole fertility issue, but really cleaning up the body so that before you go on this whole
road down infertility, let's get everything else cleaned up first. Because maybe there's other
issues. So before we stop, let's just give them sort of like our top five tips so
you know number one is avoid a seed of benefit it's likely disrupting your liver and
there's a possibility it could increase the risk of developmental disorders in children right
so so that would be one.
What's another one?
Well, avoid alcohol, but like I said, I would actually find a preconception medicine doctor
and really get your numbers checked.
Make your body this beautiful, wonderful place for a baby to grow.
And we actually have a new smart prenatal to help support many of the systems in your body.
We're pretty excited about that.
It's being very intentional with your body.
So avoiding anything that hurts it, doing things that help it.
I would also make sure the omega-3 fatty acid level in your body is really good.
There's a number of research studies correlating omega-3s.
No, it's not part of a prenatal vitamin.
You need a prenatal vitamin and omega-3 fatty acids higher in DHA and EPA.
It's not part of our prenatals either?
No, because it's hard to get the fish oil into capsules.
That's just very hard to do.
So they're separate, yeah.
So they are separate.
And then put together a stress management practice for yourself.
For sure.
A simple one, whether it's meditation, hypnosis, diaphragmatic breathing.
There's actually maternity yoga, which is awesome for women to help just like learn
how to breathe and learn how to stretch and just get your mind right.
Because as we don't want you putting toxic substances in your body like alcohol and perhaps
acetaminophen, we also don't want you having toxic thoughts because toxic thoughts actually will trigger
a cascade of toxic chemicals in your brain and it happens almost immediately.
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