Change Your Brain Every Day - Perseverance Is Key To Surpassing Mental Health Threshold With Dr. Dale Bredesen
Episode Date: April 8, 2021Experiencing pushback from the academic community, Dr Bredesen Discusses the cyclical nature of the ever changing field of mental health, and how the next generations will continue creating positive c...hange. His new book “The First Survivors of Alzheimer's: How Patients Recovered Life and Hope in Their Own Words” is a collection of stories written by people that not only survived Alzheimer’s disease, but are thriving. For more information on Dr. Bredesen's new book, The End of Alzheimer's Program, visit https://www.amazon.com/End-Alzheimers-Program-Protocol-Cognition-ebook/dp/B081Y3QF4C
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                                         Welcome to the Brain Warriors Way podcast.
                                         
                                         I'm Dr. Daniel Amen.
                                         
                                         And I'm Tana Amen.
                                         
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                                         The Brain Warriors Way podcast is also brought to you by BrainMD, where we produce the highest quality nutraceuticals to support the health of your brain and body.
                                         
                                         To learn more, go to brainmd.com. Welcome back. We are still here with our friend and colleague,
                                         
                                         Dr. Dale Bredesen, talking about his program and his just groundbreaking work in Alzheimer's,
                                         
                                         his program, The End of Alzheimer's. He's got a new book coming out in August,
                                         
                                         The First Survivors of Alzheimer's. So exciting. And in the last episode,
                                         
                                         I got super excited because you're speaking my language. Now, we're talking about diet and
                                         
                                         how ketosis really helps, you know, the brain and I just know from a day to day level,
                                         
                                         with my energy with my memory with how I feel in general, what I can get done in a day,
                                         
    
                                         when I cut out any kind of simple carbs, I just feel significantly better.
                                         
                                         So I know we're going to move on on the topic, but I just think this is such an important point.
                                         
                                         That is something you can do today. That is something you have control of today. So, you
                                         
                                         know, you can put your body into this light state of ketosis and you just focus on eating healthy
                                         
                                         fats. So I just, I don't want to minimize that.
                                         
                                         Absolutely. And you know, we found with the both with the trial and the book,
                                         
                                         these in the book, there are seven people who were all told they had Alzheimer's disease.
                                         
                                         Many of them had a very positive family histories, were having trouble at work,
                                         
    
                                         were having trouble with their children, were having trouble doing so many different things. And we're told by their doctors, you're getting Alzheimer's, there's nothing you
                                         
                                         can do about it. Then they started the protocol that we developed and we interact with them over
                                         
                                         time. And then they started getting better and better. Very exciting. And they wrote these
                                         
                                         wonderful stories, wonderful first person stories about what it feels like to have cognitive decline,
                                         
                                         how you manage day-to-day that we all hear repeatedly, and then what it feels like to
                                         
                                         begin to notice. Often you hear, at first, you don't believe it. Like, wait a minute,
                                         
                                         am I really better? Am I really finding it easier to navigate around my neighborhood?
                                         
                                         Am I really getting more ability to remember these various things, phone numbers and addresses and things like that?
                                         
    
                                         And then wait a minute, I'm back.
                                         
                                         And then they start to kind of feel like, wow, I'm really back.
                                         
                                         So it's a very exciting, I have to say, it's been the thing that I've enjoyed the most is to see people start to get better and, you know, write about their own improvement.
                                         
                                         It's just so, it's glorious to see this and to're right about their own improvement. It's just so it is glorious to
                                         
                                         see this and to see the interaction with their families and for them to then turn to their
                                         
                                         children and say, you don't have to worry about this problem. A grandfather died of this. Mother
                                         
                                         died of this. I'm now going to do better and you don't have to worry about it anymore.
                                         
                                         I love that. And I want to just point something out because when you start to eat clean and you
                                         
    
                                         cut some of that stuff out of your diet, we know inflammation is one of the big culprits right
                                         
                                         inflammation is terrible for your brain it's terrible when you're talking about alzheimer's
                                         
                                         one of your types of alzheimer's absolutely right so type one yeah so when you cut out processed
                                         
                                         foods and sugar and some of the simple carbs we're talking about when you do and you know
                                         
                                         and you right i'm talking about food right now so when you talk about and you, right, we're talking about food right now. So when you talk about these,
                                         
                                         these healthy foods, like you will feel the inflammation come down quickly when you jump
                                         
                                         on the scale. And two days later, you're down four pounds. It's not likely that you lost a
                                         
                                         bunch of fat. It's likely that you lost a bunch of inflammation, right? So you're losing this
                                         
    
                                         inflammation. You feel it immediately and you immediately feel better. That is something you
                                         
                                         can control today. So I like that.
                                         
                                         Absolutely. And I think, you know, this is a critical part of this. One message I think is
                                         
                                         so important for people to understand is please don't give up the arsenal. This is what's changed.
                                         
                                         We've all been told by the experts in the past that there is nothing that you can do. And therefore,
                                         
                                         forget just as you said, Daniel, earlier about CTE, that everyone's that there is nothing that you can do. And therefore, forget, just as you said,
                                         
                                         Daniel, earlier about CTE, that everyone's told there's nothing you can do. And so people will
                                         
                                         try something, maybe a new program, and then they say, oh, it's not working immediately,
                                         
    
                                         I'm going to give up. Please stick with it. The arsenal is huge. You can continue to tweak and
                                         
                                         tweak and tweak and tweak. And we're now looking at other neurodegenerative diseases
                                         
                                         and looking at the unique biochemistry for each one to look at how can we now get these people
                                         
                                         on the right side of their curve. And between all the different things that can be done with diet,
                                         
                                         with exercise, with sleep, with stress, with toxicity, with brain training, with vascular
                                         
                                         improvement, all of these things are available now. And things
                                         
                                         like stem cells, plasmalogens, plasmapheresis. There's some really interesting work now being
                                         
                                         done out of UCSF looking at plasmapheresis in people. So again, one of these things by itself,
                                         
    
                                         probably not the cure, but getting the right thing, getting your orchestra tuned up basically,
                                         
                                         has given the best results.
                                         
                                         Please don't give up.
                                         
                                         So both you and I have pioneered a new way of thinking.
                                         
                                         How have the academic people responded to your work and how have you managed it personally?
                                         
                                         Yeah, this is a great point. You know, there's good news and bad news.
                                         
                                         So what's happened is, you know, that there are the three three phases the first phase is they ignore you right
                                         
                                         the second phase is they get angry and they fight you and then the third phase is that they say we've
                                         
    
                                         known this all along right i think the second phase they try to kill you but yeah okay that's
                                         
                                         fair yeah so we are the good news is we're now into the second phase they're writing nasty things
                                         
                                         in uh lancetlogy, for example.
                                         
                                         It's never right. You didn't do enough patients and you didn't do this and you didn't do that.
                                         
                                         So I'm happy to say that they're very angry and very threatened. But the reality is you and I
                                         
                                         both know that treating a complex illness with a simple pill makes absolutely no sense. And I do think the pills are going to be very
                                         
                                         important. But when used appropriately, knowing the biochemistry and addressing the other things.
                                         
                                         So if you've got a roof with 36 holes in it, then in fact, the pill is a great way to cover one hole,
                                         
    
                                         but it's not going to do very well unless you cover the other 35. And that's exactly what we're doing.
                                         
                                         And you've got to figure out what are the big ones and what are the little ones for each person.
                                         
                                         So things are changing.
                                         
                                         But right now, yeah, a lot of marginalization, a lot of anger.
                                         
                                         And, yeah, for me personally, I have no question it's affected my spec scan.
                                         
                                         I have no question it's affected my campus, my amygdala, all of these sorts of things.
                                         
                                         So, yeah, it's been painful because a lot of these are my old colleagues, my old friends who are really, really angry.
                                         
                                         It's interesting. about you, then they get jealous and they get angry because they're not the ones getting the
                                         
    
                                         praise. But what matters is the patient's getting the praise.
                                         
                                         1962, Thomas Kuhn wrote a great book on the structure of scientific revolution. And he talks about five phases.
                                         
                                         And phase number one is you identify a problem.
                                         
                                         It's like standard of care isn't working.
                                         
                                         And as a neurologist,
                                         
                                         seeing patients with Alzheimer's disease,
                                         
                                         you're like, this stuff isn't working.
                                         
                                         And in fact, if you go on medications,
                                         
    
                                         like Aricept, they seem to help for a couple of months. And over
                                         
                                         time, people actually get worse than if they were not on them at
                                         
                                         all. So step two is people start to fight about what's the fix. And the standard, the status quo people
                                         
                                         make small modifications.
                                         
                                         Like in my field, the DSM, we now have six versions of it.
                                         
                                         But it's really essentially not changed since DSM-III.
                                         
                                         And then the third one is a new
                                         
                                         model is born based on experience, usually not from
                                         
    
                                         academic centers. Because it's hard to think outside of the
                                         
                                         box, when you're inside of the walls of the box. And the fourth
                                         
                                         one is the most predictable of all the stages, and that's the rejection.
                                         
                                         Yeah.
                                         
                                         And then the fifth one, because the guard dies,
                                         
                                         Max Planck said that, that progress in science
                                         
                                         happens through funerals.
                                         
                                         Yep.
                                         
    
                                         A new generation grows up up and it's accepted. And I absolutely see you're
                                         
                                         actually in stage four that you already have the model, right? I mean, the Alzheimer's,
                                         
                                         it doesn't work. The traditional treatment, it's a fraud, if you will. And people are trying to like scramble to go,
                                         
                                         no, it really is beta amyloid.
                                         
                                         And you have a new model.
                                         
                                         It's really clear.
                                         
                                         And now people hate you, which is awesome.
                                         
                                         We don't hate you.
                                         
    
                                         We love you.
                                         
                                         Feelings mutual.
                                         
                                         You just have to stay the course and for me it was always the
                                         
                                         stories of transformation that kept me going and I just stopped paying attention to the haters
                                         
                                         and as long as I don't pay attention to them I I sleep just fine. If when I engage, I mean, I really engage because how do you know unless you look?
                                         
                                         Are you insane?
                                         
                                         I'm a psychiatrist.
                                         
                                         I know how to diagnose insanity and not wanting more information.
                                         
    
                                         That's insane.
                                         
                                         So, but, you know, I don't put myself in a situation often to get angry.
                                         
                                         It's a great point, you know, and one of my very
                                         
                                         favorite sayings actually came from a rabbi who said, you are not expected to complete your life's
                                         
                                         work during your lifetime. Neither are you excused from it. Oh, you know, we're all fighting.
                                         
                                         And now I'm just about to turn 70. And so, you know, I'm thinking, hey, this is going to go
                                         
                                         on long after I'm gone. If we can do the best we can to make the major neurodegenerative disease
                                         
                                         diseases preventable and treatable, then I will be very happy that people are doing better.
                                         
    
                                         Because this, as you know, this has been the area of greatest biomedical therapeutic failure.
                                         
                                         People dying of ALS, of Lewy body
                                         
                                         disease, frontotemporal dementia, Alzheimer's disease, just go on and on. PSP, you know,
                                         
                                         these are horrible, horrible diseases that when we all trained were considered untreatable.
                                         
                                         So, you know, we're making some major inroads into these and it's just wonderful to see. And
                                         
                                         I hope it continues. By by the way your skin looks amazing
                                         
                                         i cannot believe you're about to be 70. thank you very much i appreciate that it's all the things
                                         
                                         that you guys are teaching me thank you well we have been with our friend dr dale bredesen we are
                                         
    
                                         grateful for his work for his friendship we feel like we're on the same path with a better brain, always comes a better
                                         
                                         life. With a better brain comes a better memory, comes a better mood, comes better relationships,
                                         
                                         better money, better sense of meaning and purpose. And his book, The End of Alzheimer's is just
                                         
                                         brilliant. There's not one thing I disagree with. I'd like, this is awesome. We recommend it
                                         
                                         to everyone. And thank you, Dale. It's great seeing you again. I'm always thinking of ways
                                         
                                         we should be working together because we just opened our ninth clinic in Dallas. It's so busy. It's so busy. And it's what people want.
                                         
                                         People want a better brain so they can have better lives. Yes. And it's an area that is such need. I
                                         
                                         mean, there's so many places now that are considered quote centers of excellence that are really
                                         
    
                                         centers of non-excellence. So in fact, having these places where people can actually go get prevention,
                                         
                                         get reversal, these are huge. So congratulations on the new center. Always great talking to you
                                         
                                         guys. There's so much new. I think this is, you know, the field is continuing to evolve. We're
                                         
                                         all seeing it in real time, getting better and better results. So very, very enthusiastic about
                                         
                                         the upcoming years. Thank you so much, Daniel. Thank you so much, Tana. Always great to see you too.
                                         
                                         All right.
                                         
                                         Take care, Dan.
                                         
                                         Bye.
                                         
    
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