Daniel and Kelly’s Extraordinary Universe - Listener Questions #25

Episode Date: December 23, 2025

Daniel and Kelly answer questions about kissing bugs, magnetic fields in the Sun, and microbiomes in space.See omnystudio.com/listener for privacy information....

Transcript
Discussion (0)
Starting point is 00:00:00 This is an I-Heart podcast. Guaranteed Human. Hi, Kyle. Could you draw up a quick document with the basic business plan? Just one page as a Google Doc. And send me the link. Thanks. Hey, just finished drawing up that quick one-page business plan for you.
Starting point is 00:00:14 Here's the link. But there was no link. There was no business plan. I hadn't programmed Kyle to be able to do that yet. I'm Evan Ratliff here with a story of entrepreneurship in the AI age. Listen as I attempt to build a real startup run by fake people. Check out the second season of my podcast, Shell Game, on the IHeart Radio app or wherever you get your podcasts. And she said, Johnny, the kids didn't come home last night.
Starting point is 00:00:38 Along the central Texas plains, teens are dying. Suicides that don't make sense. Strange accidents and brutal murders. In what seems to be, a plot ripped straight out of Breaking Bad. Drugs, alcohol, trafficking of people. There are people out there that absolutely know what happened. Listen to Paper Ghosts, the Texas Teen Murders, on the IHeart Radio app, Apple Podcasts, or wherever you get your podcasts.
Starting point is 00:01:09 Hi, I'm Danny Shapiro. We were in the car, like a Rolling Stone came on, and he said, there's a line in there about your mother. And I said, what? What I would do if I didn't feel like I was being accepted is choose an identity that other people can't have. I knew something can happen to me in the middle of the night, I couldn't hold on to what had happened.
Starting point is 00:01:30 These are just a few of the moving and important stories on my 13th season of Family Secrets. Listen to Family Secrets on the IHeart Radio app, Apple Podcasts, or wherever you get your podcasts. Welcome to Decoding Women's Health. I'm Dr. Elizabeth Pointer, chair of Women's Health and Gynecology at the Atria Health Institute in New York City. I'll be talking to top researchers and clinicians and bringing vital information about midlife women's health directly to you. A hundred percent of women go through menopause. Even if it's natural, why should we suffer through it? Listen to Decoding Women's Help with Dr. Elizabeth Pointer on the IHeartRadio app, Apple Podcasts, or wherever you get your podcasts.
Starting point is 00:02:19 A new deadly bug has been found in the state for lovers. Should my family and I be quaking under our covers? If Maxwell was right, then magnetic field lines shouldn't ever snap. But field lines break in the sun, so was Maxwell full of... When Daniel's wife comes on the show, she often talks about poop, which got me thinking of microbes in space. So, what's the scoop? Whatever questions have been keeping you up at night,
Starting point is 00:02:50 Daniel and Kelly's answers will make it all right. Welcome to Daniel and Kelly's Extraordinary Universe. Hi, I'm Daniel. I'm a particle physicist, and I wish I'd heard this episode before I visited Virginia. Oh, come. I'm going to note that the thing I'm going to talk about is a problem for California, too. So watch it. Hello, I'm Kelly Weeter Smith.
Starting point is 00:03:23 I study parasites and space. And this might be the first episode where we talk about. talk about parasites and space for me. So we've got it all for me. And reasons to not visit Virginia. Or California. We'll have to work in some cannibalism and then it'll be the full suite of DQQ checkboxes. We're going to talk about poop. So we already know we've got that taken care of. All right. So then, Kelly, my question for you is, on average, how much poop does an adult human ingest accidentally in their life? You think I've just got that kind of information, like, ready to share with people. I feel like this is less a question and more
Starting point is 00:04:01 some insights into what kind of person you think I am. I have no idea, Daniel. It's probably a lot. You're actually, your wife seems like she would know. Do you know the answer? Was this a quiz? It's not a quiz. I do not know the answer. But last time, we were very happy to talk about the butt-to-mouth pipeline or whatever you called it. So poop to mouth, poop to mouth. Poop-to-mouth. Poop-to-mouth. There you go. Yeah, yeah. I mean, let's just say that a lot of poop to mouth transmitted diseases are very common. So the answer has to be a lot. Yeah, you know, it's got to be a lot. I'm just wondering what are the correct units even for describing it. We're talking kilograms, metric tons, micrograms, just like, what are we looking at here? If you looked at a pile of all the poop you accidentally ingest in your life, how big would it be? Oh, gosh, gosh. I hope it's grams and not pounds or kilograms, I guess. I'll keep the same units. I hope it's grams and not kilograms. But who knows? There you go.
Starting point is 00:04:58 Things to look forward to. And that's just a little taste, ha, ha, ha, of what you have to look forward to on today's episode. Gross. Today we're answering questions about things people are curious about, things they wonder about, things they desperately need to know the answers to, but can't find satisfaction on the internet,
Starting point is 00:05:15 including chat GPT. So they write to us. And you are also very welcome to write to us. And please don't ask your physics questions to chat GPT. It doesn't know what it's talking about. Instead, write to us to questions at danielandkelly.org. We will give you a real answer from real humans that reflects real physics or biology. Plus poop jokes.
Starting point is 00:05:37 Actually, I bet chat chippy tea could do some good poop jokes. I don't know. I've asked it to do 10 jokes about parasites, and I incorporated that into my speech as president of the Helmothological Society of Washington, and they weren't very funny. I got to say, it wasn't very good. All right, well, let's get right into it. Our first question comes from Zach, and it's a question about a disgusting disease slash parasite. Yay. And I got to say, you know, Zach, I'm a fan of for a variety of reasons.
Starting point is 00:06:06 He found our podcast through SMBC, so he's been a longtime Weiner Smith supporter. And he was the first one to refer to our audience as The Extraordinaries, which I have absolutely stolen from him and use regularly. Because our audience is extraordinary. Absolutely. Yes, I adore the Extraordinaries. And so Zach is an extraordinary, and let's hear what Zach had to ask. Hey, there, extraordinaries. This one is definitely for Kelly.
Starting point is 00:06:32 I just saw a headline about a deadly disease being spread in Virginia by something called a kissing bug, and that the disease is some kind of parasite. So I'm wondering if you as a Virginian should be worried. Should I be worried? Looking forward to learning more, I think. All right, Kelly, tell us all about this. and everybody stop eating your breakfast or lunch or whatever it was. I mean, probably anytime I open my mouth to say something, you should do that.
Starting point is 00:07:01 But, all right, so the reason you worry about kissing bugs is because kissing bugs can transmit a disease called Chagas disease. Well, what is a kissing bug to start with? And why is it called a kissing? So there are these bugs that are, you know, like maybe about the size of a quarter. In Latin America, they tend to live in houses like wedged into cracks in the walls. They're called kissing bugs because they tend to bite on your face, for example, around your lips and stuff. So you don't kiss the bugs. The bugs actually keep you from being able to kiss other people because you have these gross bug bites on your lips.
Starting point is 00:07:32 I mean, it depends on who you are, you know. No judgment. That's true. If that's your thing, all right. But so what you really have to worry about with these bugs is that they can be infected by a disease called Chagas disease. And this is a protozoan, it's unicellular. We were talking about malaria a while back, and malaria is also a unicellular protozoan parasite. They both live inside cells.
Starting point is 00:07:59 So malaria lives inside our blood cells. Trapanosoma Cruze, which is the parasite that causes Chagas disease, can live inside things like muscle cells, and your heart is a muscle, for example. And that's going to become a problem. So what happens is a kissing bug bites you, usually while you're sleeping, because they're active at night. So it can bite like... Wait, they're crawling on your face at night while you're sleeping and biting you near the mouth? Yeah.
Starting point is 00:08:26 Oh, no. Yeah, I know. Virginia is for lovers. Hey, hey, okay. All right, you know what? Back up. Where do you find kissing bugs in 29 states in the United States. So if you drew a line maybe like three quarters of the way up the United States,
Starting point is 00:08:43 all the states below that line have kissing bugs, including California. And I would bet you that California. has a higher caseload than Virginia does, for reasons we'll get to later. So watch it. All right. I'm getting saucy here. I was just saying Virginia is for lovers. I don't know what you're going off about here. I saw your face. I knew what you meant. So you're sleeping, peacefully, dreaming of vacations in Southern California, and some bug is crawling across your face and biting you on the lips. And inside of it, it's got this protozoan. Yeah, right. And so when you get bit by a mosquito that has malaria, the virus essentially gets, injected into you with the saliva. But here what happens is the parasite takes a really big blood
Starting point is 00:09:27 meal and it fills its body up so much that it expels its feces. Oh. I know. I'm so sorry, everybody. And then when you wake up in the morning, the spot where you got bit itches. And so you scratch and you scratch the feces into your wound. And that's how you get infected. Or maybe you rub your eye and you scratch the feces into your eye and that's how it gets in. And so... I know my role here is to like digest this. this and repeat it, but I really just don't even want to save these things coming out of my that's really repulsive. Oh, my gosh.
Starting point is 00:09:58 All right. It's pretty unpleasant. There's some other routes that you can apparently get it. Like, if you live in areas where there's loads of these insects and they happen to get, like, ground up into your food, you can get the parasite by ingesting it. Mom can transmit it to baby if she gets it when she's pregnant. Blood transfusions. But in the United States, we check blood for Chagas disease, so that shouldn't be happening here.
Starting point is 00:10:20 So the parasite. comes through the feces of the kissing bug. But that's different from the mosquito, right? When the mosquito takes its blood meal, the parasite goes down its little straw, right? Yep, exactly. So, like, if you, you know, if you were a partner woke up and looked at you
Starting point is 00:10:34 and was like, you just got bit by a kissing bug, hold on, and they get like an alcohol wipe and they swipe away from where you got bit, then you could make sure you got no feces in your wound and you'd probably be okay. But usually what happens is you wake up groggy and it kind of itches, so you rub your face and you rub it in there.
Starting point is 00:10:51 If your partner wakes up and you have bug poop on your face and their first instinct is like, I'm going to take care of this for you. You have a nice partner. What do you think they should do? No, they should take care of it for you. But instead, they're like, oh, my God, that's revolting. Get out of bed. But, okay, so you might be imagining like a human-sized turd.
Starting point is 00:11:10 This is. I wasn't until you said that and now I am. Thank you. Sorry. But no, this is like a tiny. little speck, like you might not, it's not going to be obvious. Your partner's not going to. Oh, that's okay. Yeah. It's a tiny little speck of poop on my face. That's no big deal. Thank you. Oh, yeah. I feel great about it now. Yeah. All right. Well, hold on for a later episode where we talk about the mites that
Starting point is 00:11:37 are living in your eyebrows that are pooping on your face all day. So, you know, you don't always see it. All right. So it gets into my blood because I've scratched this bite on my face and rub that tiny little dainty bit of poop into the bite and then what happens to me. All right. So early symptoms are kind of nondescript things. You can have like a fever, loss of appetite, diarrhea, vomiting, enlarged lymph nodes, fatigue. But most people will present no symptoms. One obvious symptom is that there's this thing called Romagna sign, and I'm sorry, I'm sure I mispronounced it, which is what we all have come to expect for me, which is a swelling around like the eye or the part of the face where you got bit by a kissing bug. And so if you get that, then you should like immediately go to the doctor
Starting point is 00:12:22 and be like, I've got chagas. And they have anti-parasite treatments that you can get. And so if you've got this swelling, you should go in right away and get the parasite wiped out. But what really becomes a problem is if you don't catch the parasite early on, it becomes much harder to treat. And what the parasite does is it's living in cells. And it's replicate, I know, it's replicating in your cells. And every once in a while, it will kill the cell as it breaks out. And it. and your body will produce inflammation around the area where the parasite is living. And so for, you know, some people who have this parasite for decades,
Starting point is 00:12:56 they'll start to get enlarged hearts from, like, the inflammation, and they can have heart failure, that can result in death, or they can have digestive problems. I think the parasite also lives in, like, the cells in your digestive tract. And so you can get enlarged esophagus, enlarged colon, or you can have trouble eating or using the restroom. And in these cases, it's much. harder to treat the parasite. Like you can give some treatment to try to slow the rate at which
Starting point is 00:13:21 it's spreading to the other cells. But once it's firmly established in your cells and they're like safe inside your cells, it can be pretty hard to combat. And in that case, you are mostly just trying to reduce the symptoms associated with having an enlarged heart or an enlarged colon and stuff like that. So should I worry? Yeah. Don't you worry anyway? Whether or not you should. That's right. I worry about everything. Exactly. And two states that have, you know, more Chagas disease than most of the rest of the United States include Texas and Florida. And for a while, I lived in Houston. And so I did a bunch of research because I had a young daughter and I was worried we were going to, you know, all get Chagas disease. And I convinced myself that I personally don't have to
Starting point is 00:14:07 worry much. Here's why. But you've done an internet deep dive that actually swaged your worries. It doesn't always just inflame your worries? You know, I actually feel like for people who worry about parasites, the more you learn about them, the less you worry because a lot of them have like very clear paths to infect people. And once you know, that gives you the power to avoid them or at least to understand what behaviors are risky and what aren't. So, yes, in this rare case, I decided I'm not going to worry. And deciding not to worry always makes it possible to not worry, right? Oh, no, those are different things. Those are different things.
Starting point is 00:14:45 What I do worry about, though, is most of the people in the United States who have Chagas disease are people from Latin America. So this disease is a neglected tropical disease. It's much more common in like Central and South America in areas where the housing tends to have like more nooks and crannies and be less insulated. And so it's easier for the bugs to get inside of the house or inside of like factories that make juice and stuff like that where the bugs can get. sort of ground up with the rest of the juice. So most of the people who have it in the United States are immigrants. And so what I worry about is that our doctors aren't good at recognizing this because it wasn't a problem in the United States and we're sort of only recognizing that it's a problem because people have moved to the United States with it. And so I think often
Starting point is 00:15:32 a lot of people don't get diagnosed when they could get diagnosed and there's blood tests now. And so I feel like one good thing about the fact that this parasite has made it into the news and I'm hearing from like friends and family members who haven't written in decades because they remembered Kelly studied parasites and they want to know if they should worry about kissing bugs. And I'm happy to answer those questions. But I think one of the good things is this is getting on people's radars now. And so I'm hoping that people thinking, oh gosh, this could infect me, will maybe allow us to raise some money so that we can raise awareness about this, make sure it's on every doctor's radar. Maybe we could get some better treatment, some better medications. But me living in a house that's
Starting point is 00:16:09 well sealed, and as someone who would be able to identify a kissing bug in the house, if it got in the house, I'm not personally worried. I'm a little worried about, like, dogs that sleep outside at night, and I have a livestock guardian dog. I mean, this can infect any mammal, so like possums and raccoons tend to have it. I'm sure, you know, this could be much more of a problem for people who are unhoused. But as a housed person in a well-insulated secure house, I am not personally worried. All right. Well, thank you for the deep download of information, as disturbing as some of it was. Sorry, just real quick, I want to say, I am not a medical doctor. And so if you are concerned that you have Chagas disease, you should talk to a doctor. And, you know, just because I'm worried doesn't mean there's absolutely zero risk that it could be in your house. And this is where I reveal that I have anxiety. And so I still worry sometimes a little bit. But I think most of your worry should be about the population of people who might have picked up Chagas disease from their home countries and brought it here. So we should be trying to help those people.
Starting point is 00:17:05 All right. So let's check him with Zach and see if this made him more or less. worried. Hello again, Extraordinaries. Thank you so much for answering my question about kissing bugs. You definitely gave a more thorough explanation than I was even hoping for, as usual. It sounds like as a Minnesotan, I don't personally have to worry about this unless I'm traveling somewhere warmer, but I appreciate the opportunity to spread some public health knowledge and maybe get some more visibility for a disease that could really impact people who aren't me. Thanks again. Hi, Kyle, could you draw up a quick document with the basic business plan?
Starting point is 00:17:50 Just one page as a Google Doc, and send me the link. Thanks. Hey, just finished drawing up that quick one-page business plan for you. Here's the link. But there was no link. There was no business plan. It's not his fault. I hadn't programmed Kyle to be able to do that yet. My name is Evan Ratliff. I decided to create Kyle, my AI co-founder, After hearing a lot of stuff like this from OpenAI CEO Sam Aldman, there's this betting pool for the first year that there's a one-person billion-dollar company, which would have been like unimaginable without AI and now will happen. I got to thinking, could I be that one person?
Starting point is 00:18:24 I'd made AI agents before for my award-winning podcast, Shell Game. This season on Shell Game, I'm trying to build a real company with a real product run by fake people. Oh, hey, Evan. Good to have you join us. I found some really interesting data on adoption rates for AI. agents in small to medium businesses listen to shell game on the iHeart radio app or wherever you get your podcasts for 25 years i've explored what it means to heal not just for myself but alongside others i'm mike delarocha this is sacred lessons a space for reflection growth and collective
Starting point is 00:19:02 healing what do you tell men that are hurting right now everything's going to be okay on the other side you know, just push through it. And, you know, ironically, the root of the word spirit is breath. Wow. Which is why one of the most revolutionary acts that we can do as peoples just breathe. Next to the wound is their gifts. You can't even find your gifts unless you go through the wound. That's the hard thing.
Starting point is 00:19:27 You think, well, I'm going to get my guess. I don't want to go through all that. You've got to go through the wounds you're laughing. Listening to other people's near-death experiences, and it's all they say. In conclusion, love is the answer. Listen to Sacred Lessons as part of the My Coutura Podcast Network, available on the IHeart Radio app, Apple Podcasts, or wherever you get your podcast. Hey, I'm Kelly, and some of you may know me as Laura Winslow.
Starting point is 00:19:52 And I'm Telma, also known as Aunt Rachel. If those names ring a bell, then you probably are familiar with the show that we were both on back in the 90s called Family Matters. Kelly and I have done a lot of things and played a lot of roles over the years, But both of us are just so proud to have been part of Family Matters. Did you know that we were one of the longest running sitcoms with the black cast? When we were making the show, there were so many moments filled the joy and laughter and cut up that I will never forget. Oh, girl, you got that right.
Starting point is 00:20:20 The look that you all give me is so black. All black people know about the look. On each episode of Welcome to the Family, we'll share personal reflections about making the show. Yeah, we'll even bring in part of the cast. some other special guests to join in the fun and spill some tea. Listen to Welcome to the Family with Telma and Kelly on the IHeart Radio app, Apple Podcasts, or wherever you get your podcasts. Hi, I'm Dr. Priyank Wally. And I'm Hurricane Dubolu.
Starting point is 00:20:50 On our new podcast Health Stuff, we demystify your burning health questions. You'll hear us being completely honest about her own health. I'm talking about very serious stuff right now, and you're laughing at me. And you'll hear candid advice and personal stories from experts who want to make health care more human. Sometimes you're there to listen, to understand, to empathize, maybe to give them an understanding or a name for what's going on. That helps people a lot, understanding that it's not just in their head. We are breaking down the science, talking with experts, and sharing practical health tips you can actually use in your day-to-day life. From when to utilize and avoid artificial light to how to sleep better.
Starting point is 00:21:31 Everything you need to know about fiber and how to build. poop better. How to minimize the effects of jet lag and how to stay hopeful in times of distress. We human beings, all we want is connection. We just want to connect with each other. We want to make health less confusing and maybe even a little fun. Find health stuff on the iHeartRadio app, Apple Podcasts, or wherever you get your podcasts. All right, we're back. We're going to do a major pivot from earthly questions about the butt-to-mouth pipeline to lines of plasma in the sun.
Starting point is 00:22:14 It's hard for me to see how we're going to get to cannibalism with this question, but hopefully we make it. Well, if the sun absorbs the earth, is that sort of like solar system cannibalism? It's a stretch, Daniel. It's a stretch. I might give it to you, but I think that's not what most people are thinking of. All right. Well, here's a really insightful question about a very subtle point. of magnetism from Michael Woodhams.
Starting point is 00:22:36 When I was a physics student, I learned about magnetic fields via Maxwell's equations. Magnetic field lines never join, never intersect, and never terminate. So it's impossible for one field line to pass through another. But when I studied astronomy, I learned that in the corona of the sun, magnetic fields get so twisted that they break and reconnect, resulting in a solar flare. What's missing from Maxwell's equation description that lets this happen? can we observe this reconnection happening in a laboratory? Ooh, okay, there's a lot of different ways we could enter this question.
Starting point is 00:23:09 Let's start with what is a field. Yeah, so Maxwell's equations are the ones that tell us how electricity and magnetism work, and specifically how they slosh back and forth between each other, how electric currents can cause magnetic fields, how changing magnetic fields can cause electric currents, all sorts of stuff. It's a brilliant piece of work from 150 years ago, which was then updated in quantum mechanic eyes by fine, and other folks to our modern understanding of electricity and magnetism.
Starting point is 00:23:36 Yeah, and for more history of Maxwell's equations, folks should listen to our episode with Kathy does physics because she gave so much great insight into this story. But anyway, sorry, I remember Maxwell got a lot of equations wrong, and that made me feel great, and someone else had to fix it. So sorry, go ahead. Yeah, his notation was really confusing, and he made a lot of mistakes, and it was Heaviside who came in and cleaned it up. He spent, like, a decade alone in like an attic working on these equations, and the equations
Starting point is 00:24:01 we now know and love are mostly actually due to heavy sides formulation. A lot of important work done by a lot of people. But the central concept of Maxwell's equations are these fields, the electric field and the magnetic field and how they relate. So let's start, since we're going to be talking about field lines, let's remind ourselves, what is a field anyway? So when I picture a field, I like literally picture a soccer field that maybe undulates sometimes. So correct, you're laughing. So that must be pretty wrong. No, it's actually pretty accurate. Okay.
Starting point is 00:24:35 Yeah, a field in physics is just assigning numbers to space, to saying, let's put the number seven here, let's put the number nine there. And if you have numbers everywhere in space, that's a field. Electricity and magnetism are more complicated fields because at every point in space, they don't have a number, they have a vector. They have three numbers,
Starting point is 00:24:54 so like a little arrow with a direction and a length. So the electric field is like a little arrow at every point in space, and the same for the magnetic field. Okay, got it. I can picture that. All right. Now, this field, it's a really important concept, and physicists talk about it as if it was real, like the field is out there, but we don't really know that.
Starting point is 00:25:14 Philosophically, it's just sort of like a construct we use to explain phenomena we observe, and it's a very useful intermediate. We don't really know if the field is physical. Like, it's a field there when you're not measuring it. You can't see it directly. All you can do is, like, drop a particle into it and see. sees effects. So remember that a field is sort of like a construct. All right. So are we getting philosophical or does this impact like predictions as well? I just can't talk about fields without
Starting point is 00:25:40 mentioning that this is something we don't know if it actually exists or not. And I'm here for the philosophy too. And that's important because the next thing we're going to talk about is extra philosophical, which is a field line. So often we try to describe field. We try to like draw fields on paper. And one thing you could do is like draw a bunch of arrows at every point in space. And that technically is a good description of the field, but it's kind of hard to look at. And so instead, people develop this concept of a field line. And a field line is a line that points along the direction of the field. So mathematically speaking, it's tangent to the magnetic field vector.
Starting point is 00:26:16 More practically, if you're looking at a bar magnet, you can draw like field lines from north to the south. That shows you the direction of the magnetic field along that line. And you can draw more lines, and you put them closer together where the magnetic field is changing a lot and further apart when it's not changing. So in that sense, there's sort of like lines on a contour map that show you where the height is equal. Here it shows you where the magnetic field is constant and the direction along which a compass would point if you put it there. Okay, so I'm imagining my undulating soccer field that is made up of three points and I've
Starting point is 00:26:50 got arrows and they've got different heights. Is there like a line above each arrow or like above each set of arrows? I guess it could be whatever you decided you want. Is that like a reasonable way to imagine it? It's like if you find a bunch of arrows that are all pointing along the same direction, you would draw a line along them. Okay. So back to our example of contour lines, imagine if you have a hill and you draw contour lines around it, like a circles, what happens when that hill gets flattened? Where do the contour lines go? How do you draw contour lines on a flat plane? You could draw them in lots of different ways. They're sort of arbitrary. So imagine now you're you have a hill that becomes flat and then it becomes a divot. So
Starting point is 00:27:31 the contour lines in that sense are discontinuous because it's that moment when they're not really well defined in the middle. And that's what's happening with the plasma flux tubes in the magnetic field. There are clear field lines in one direction, but then there's this moment when the flux tubes are crossing and things cancel out and you don't really know how to draw the field lines. And then a moment later, you know how to draw them again. And so there's a discontinuity from before to after. Got it. Okay. But these are lines that we have drawn in our minds. Magnetic field lines, not physical things.
Starting point is 00:28:02 You can't, like, go out and touch one and push one, right? Somebody else could draw lines differently than you do. So they're helpful for understanding the flow of the magnetic field, but they're not physical things themselves. Got it. Okay. They're a human construct to describe behavior. Exactly. Like, in the same way that if you're hiking and you're using a contour map, you shouldn't look for those lines in the ground to know where you are, right? That's foolish. That would be confusing. They actually made me kind of helpful for hiking, right?
Starting point is 00:28:30 Yeah, sure. I wouldn't want to be the one who had to, like, draw the contour lines, but yeah. Exactly. All right. So Michael makes this point that contour lines don't terminate. They don't break, right? And this is the property of magnetic fields only, not electric fields, because we don't have magnetic monopoles in our universe.
Starting point is 00:28:47 A north pole or a south pole is where a magnetic field would begin. So if you had just like a north pole out in space by itself, the magnetic field lines would all point away from it. The same way if you put an electron in space, the electric field all points away from it or towards it, depending on the charge of the particle. And so in our universe, we have no single north poles or single south poles. They all come together. They're dipoles. We have no magnetic monopoles in our universe. And we've talked about that on a previous episode. So I'll just leave that there. But what that means is that magnetic field lines don't start or end. They're always in a loop. So if you have like a bar magnet, there is a magnetic field that's
Starting point is 00:29:25 starts from the North Pole and then goes down to the South Pole, but then it goes through the bar magnet between the South and the North Pole. So it always forms this continuous loop. In order to have a magnetic field line that ends somewhere, you'd need an isolated North Pole or an isolated South Pole. You'd need a monopole. Okay, and Maxwell proved that with his equations? Is that right? A great question. Maxwell's equations show you that you can't have a break or an end to a magnetic field if you have no monopoles. But if you did find a monopole, then that would do that, right? But we've never seen a monopole. As far as we know, there are no monopoles in the universe. So all magnetic field lines are loops for that reason. Got it. Okay. But not on the sun? So now we're set up to talk about the
Starting point is 00:30:10 sun, which is like maybe the most complicated electromagnetic object in the neighborhood, right? Because it's plasma. Plasma is an ionized gas. So you take something like hydrogen, which which has a proton and an electron, and you heat it up so that the electrons are no longer bound by the protons. They're flying around free. So you have a gas, which is already very complicated to model because it's high density, high pressure, it's chaotic. And now you add the fact that there are electric charges on all those particles. So not only do you have to deal with complicated fluid dynamics, plus you have electric and magnetic fields in there. So this is a whole area of study. It's called magneto hydrodynamics, and it's famously a headache.
Starting point is 00:30:52 I mean, but it sounds pretty cool. It has a cool name. Yeah, that's true. So the equations of magneto-hydrodynamics are the equations of fluid dynamics, which are famously complicated, plus the equations of electromagnetism. And so you get all these really complicated effects. And in the sun, you get these tubes of plasma that are flowing like currents. And because it's electrically charged, there is an electric current, and so you get magnetic fields generated in lines around them. And there's really complicated behavior because the sun is chaotic and turbulence.
Starting point is 00:31:25 So these tubes of plasma, sometimes they're flowing nicely alongside each other like lanes on a highway. But sometimes somebody crosses the lane and everything gets tangled up and the tubes do all sorts of crazy stuff and they snap and they rearrange. And when that happens, you get crazy effects from the magnetic fields also. And just to be clear, so I think you told me in a previous episode that we really have never seen a monopole. And so it's not that the sun is creating monopoles, something else. It's just all this craziness when they're intersecting and fluids. Exactly. The sun is not creating monopoles as far as we know.
Starting point is 00:31:59 But many popular science treatments describe this behavior where complicated tubes of plasma are crossing and snapping, doing all sorts of stuff, as magnetic field lines tinkling and breaking. And this is what Michael is asking about. He's like, doesn't that violate Maxwell's equations? And the answer is, no, it doesn't violate Maxwell's equations, though the description is a little bit confusing, and we're going to take it apart and make it clear. All right. Take it apart, Daniel. So what's happening is that you get plasma currents, and sometimes they're going opposite directions, sometimes they're the same directions, but they come near each other. And sometimes when they come close to each other, the magnetic field between them can cancel. Remember that magnetic fields are a vector, and they're linear.
Starting point is 00:32:42 So if you have like a magnetic field generated by one object that's in one direction and a magnetic field in the exact opposite direction generated by something else, they can cancel each other out. So you can have an area between two like tubes of plasma with no magnetic field in it. The two things can cancel, even if you're in an area of very strong magnetic activity, right? This is just like destructive interference between waves, right? You can have a point in a wave where there's no amplitude. And so that's what's happening, that there are locations between these plasma flux tubes that have no magnetic field because of this cancellation.
Starting point is 00:33:18 And at that point, the direction of the field lines are not well defined. You could draw them in lots of different directions because the field is zero there, and the derivative can be zero as well. And so if you're going to sit down and draw the field lines, you have some arbitrary choices to make. And the moment before that happens, and the moment after that happens, the field lines you would draw are very different. So yes, the field lines from one moment to another have like a discontinuity where you're like, before this thing happens, I would draw the field lines here.
Starting point is 00:33:49 Just after it happens, I would draw the field lines there. And there's not a smooth transition where you can say at every moment the field lines move. But remember, field lines are arbitrary. They're what we make up in our minds, just like our description. It's like back to our contour example, if you had an earthquake and you had to draw contour lines over a peak somewhere, you're like, well, I could draw contour line in maybe. any different directions as this peak is shifting and going up and down. And so there's a moment there where you don't know exactly how to draw the field lines. So what's really happening is the
Starting point is 00:34:19 physics, the physical things that's happening is that these flux tubes are breaking and snapping and doing all sorts of crazy stuff. And that's creating the solar flare where the sun is going to spit out a huge arc of plasma, which maybe is going to eat the earth in an act of astronomical cannibalism. Oh, nice. Thing! And the field lines are confusing. But the field lines are confusing, but the field lines are not breaking. There's no divergence there. There's no source of the field lines. It's just that the field lines, you draw them one way, and then you would draw them another
Starting point is 00:34:47 way a moment later. So they are not actually breaking. There are no monopoles in the sun. Okay, so I'm trying to decide, does the fact that we're not calling this a break like make this concept less useful? Because it's clearly a human construct.
Starting point is 00:35:03 Or does this just teach us something particularly important about the sun in framework that we've created. I think it also teaches us something about the limitations of language. You know, the field lines transition from here to there, but they never have any divergence. They are continuous. There's never an end point, even though there's a discontinuity from moment to moment about how you would draw them. So yes, the sun is chaotic and we have a lot to learn about how plasma works and how to keep it stable. And we've done a bunch of experiments to see
Starting point is 00:35:33 these kinds of effects here on Earth. That's the second part of Michael's question. Yes, we see this kind of stuff happening all the time in magnetic confinement fusion when we build Tokomax to try to recreate the conditions of the sun so that we can have fusion here on Earth. And this is something people work on and struggle with. They try to minimize the chaos and keep those flux tubes steady. And so there's lots of observations of these kinds of effects in the lab. Usually it's what you don't want to happen. But we see it anyway.
Starting point is 00:36:02 So plasma turbulence is definitely something we've seen in the lab. We can recreate. We struggle to model it because turbulence is very difficult. difficult. It requires serious computation because it's chaotic, so it's very, very sensitive to the initial conditions. But it's not new physics in the sense that it's like a magnetic monopole or violating Maxwell's equations. Can we still apply Maxwell's equations in these conditions? Oh, yeah. Okay. Absolutely. The only time you can't apply Maxwell's equations is when you have quantum effects, like the level of photons and individual particles doing
Starting point is 00:36:34 quantum stuff. But the sun is big and basically classical, and so you can definitely use Maxwell's equations to describe it. And then when there are quantum effects, you use quantum electrodynamics, which is just the quantum version of Maxwell's equations anyway. So yeah, Maxwell was right as far as we know. Okay. And so that wouldn't be quantum magneto hydrodynamics, which sounds even cooler, right? That would be a different field? I'm not aware of that, but that's a cool title for a grant proposal. There you go. All right, let's see if Michael feels like he understands Maxwell's equations a little better now. Thank you. That was an informative answer. I enjoyed the description of magnetic field lines.
Starting point is 00:37:15 Ever since sending in this question, I've been wondering how you'd handle that. I am mildly surprised that the magnetic field lines manage their realignment trick without resorting to quantum mechanics. Hi, Kyle. Could you draw up a quick document with the basic business plan? Just one page as a Google Doc and send me the link. Thanks. Hey, just finished drawing up that quick one page business plan for you. Here's the link. But there was no link. There was no business plan. It's not his fault. I hadn't programmed Kyle to be able to do that yet. My name is Evan Ratliff. I decided to create Kyle, my AI co-founder, after hearing a lot of stuff like this from OpenAI CEO Sam Aldman. There's this betting pool for the first year that there's a one-person billion-dollar company, which would have been like unimaginable without AI and now will happen.
Starting point is 00:38:10 I got to thinking, could I be that one person? I'd made AI agents before for my award-winning podcast, Shell Game. This season on Shell Game, I'm trying to build a real company with a real product run by fake people. Oh, hey, Evan. Good to have you join us. I found some really interesting data on adoption rates for AI agents and small to medium businesses. Listen to Shell Game on the IHeart Radio app Or wherever you get your podcasts
Starting point is 00:38:35 For 25 years, I've explored what it means to heal Not just for myself, but alongside others. I'm Mike De La Rocha. This is Sacred Lessons, a space for reflection, growth, and collective healing. What do you tell men that are hurting right now? Everything's going to be okay on the other side, you know, just push through it.
Starting point is 00:38:58 And, you know, ironically, the root of the word spirit is breath. Wow. Which is why one of the most revolutionary acts that we can do as peoples just breathe. Next to the wound is their gifts. You can't even find your gifts unless you go through the wound. That's the hard thing. You think, well, I'm going to get my guess. I don't want to go through all that.
Starting point is 00:39:18 You've got to go through the wounds you're laughing. Listening to other people's near-death experiences, and that's all they say. In conclusion, love is the answer. Listen to Sacred Lessons as part of the My Coutura Podcast Network, available on the IHeart Radio app, Apple Podcasts, or wherever you get your podcast. The social media trend that's landing some Gen Z years in jail. The progressive media darling whose public meltdown got her fired. I'm going to take Francesco off the network entirely.
Starting point is 00:39:49 The massive TikTok boycott against Target that makes no actual sense. I will continue getting stuff from Target. and I will continue to not pay for it. And the MAGA influencers, whose trip to the White House ended in embarrassment. So refreshing to have the press secretary after the last few years who's both intelligent and articulate. You won't hear about these online stories in the mainstream media, but you can keep up with them and all the other entertaining and outrageous things happening online, in media and in politics, with the Brad versus Everyone podcast,
Starting point is 00:40:17 hosted by me, Brad Palumbo. Every day of the week, I bring you on a wild ride who the most delulu takes on the internet, criticizing the extremes of both sides from an independent perspective. Join in on the Insanity and listen to the Brad versus Everyone podcast on the Iheart Radio app, Apple Podcasts, or wherever you get your podcasts. Hey, I'm Kelly, and some of you may know me as Laura Winslow. And I'm Telma, also known as Aunt Rachel. If those names ring a bell, then you probably are familiar with the show that we were both on back in the 90s called Family Matters.
Starting point is 00:40:50 Kelly and I have done a lot of things and played a lot of roles over the years. Both of us are just so proud to have been part of Family Matters. Did you know that we were one of the longest running sitcoms with the black cast? When we were making the show, there were so many moments filled the joy and laughter and cut up that I will never forget. Oh, girl, you got that right. The look that you all give me is so black. All black people know about the look. On each episode of Welcome to the Family, we'll share personal reflections about making the show.
Starting point is 00:41:21 Yeah, we'll even bring in part of the cast and some other special. guest to join in the fun and spill some tea listen to welcome to the family with telma and kelly on the iHeart radio app apple podcast or wherever you get your podcasts all right we're back we started on earth understanding kissing bugs and poop then we went out into space to understand what's happening in the sun. And now we're going to bring that all together to talk about poop in space. Yeah, you know, I love, I study parasites and space. We've got both of them in one episode and poop is what connects them. Amazing. And that is a good summary of my life.
Starting point is 00:42:10 So we should have invited our vice president for poop research on this podcast, yeah. Why is she not president of poop research? You're clearly not president of poop research. Well, we got a lot of vice presidents, you know, and so the vice president, for this, vice president for that. Got it. All right. She should be president. Yeah, I'll propose that to the next board meeting.
Starting point is 00:42:31 Okay, yeah, that sounds good. It doesn't seem like anyone else in your family's qualified. I'll just say, but all right. And I think that we should send our answer here, not just to John, but also to Katrina for a response. Oh, I'm nervous. Y'all should have seen Kelly's face. Well, the president of poop research at the Whiteson Institute.
Starting point is 00:42:49 I mean, this is a big deal. Okay. Yes. Your adjunct status at the Whiteson Institute might be on the line here. here. Oh, no. I guess the good news is I don't get a lot of perks from that adjunct status. What? What? The prestige alone. Oh, my gosh. That's right. I guess I get friendship, which is the most valuable thing on this planet. All right. Let's stop beating around the bush, and let's hear John's question about poop in space. Hello, Daniel and Kelly. I had three
Starting point is 00:43:15 questions in regards to the microbiome in space. First, do the microbiomes of all the people on the ISS at a given time become the same? Second, how do things change with every supply delivery or crew change? And third, how does zero-g affect the microbiome? Thanks. Oh, my gosh, loads of amazing questions here. So I split these questions up. So first, let's talk about, do the astronaut microbiomes become the same on the
Starting point is 00:43:42 International Space Station? And let's start by saying they don't become the same, but they do become more similar. So, you know, the same would imply the exact same species and the exact same abundances. That's not what happens. All right. Well, let's start by reminding people what a microbiome is and why it might become the same anyway. Oh, okay. Well, I just assume that all of our listeners have listened to all of Katrina's amazing episodes. I'm going to butter Katrina up here at the beginning of the answer. All right. Nice. So, all right. So, you know, your microbiome is the collection of viruses, bacteria, fungi that live all over your body, including in your gut, on your. your face, in your saliva, you know, in your mouth, on your teeth. They're everywhere. And they can
Starting point is 00:44:25 be important for a lot of different reasons. They can, you know, support inflammation, which is bad for you. They can help you digest food, which is good for you. They can help you battle pathogens, which is obviously good for you. And so it's a dynamic community that changes over time for a variety of reasons. And one of the ways that it changes on Earth is if you move in with somebody new. And you spend a lot of time with them. You, over time, have microbiomes that are more similar. Not necessarily exactly the same because maybe you all are eaten different foods when you're at work or something like that. But you have more similar microbiomes when you live with someone over time. So you love someone, you live with them, you end up eating
Starting point is 00:45:03 their poop. Yeah. Another example of the but-to-face pipeline. That's right. I mean, even if you don't love them, but you live with them, you're probably eating their poop. I feel like it's easier to digest that fact. if you do love them, but anyway. All right. All right. So then the fascinating question is, we know that happens for roommates here on Earth. And the question is, what about roommates in space? How does this happen and is affected by supplies or crew changes or zero G? Yeah. All right. So there was, I was able to find a study where they looked at astronauts, nine of them, that were in space for somewhere between six to 12 months on the international space station. And they looked at their microbiomes on
Starting point is 00:45:45 different parts of their bodies. And then they compared the microbiomes on different parts of their bodies. And then they compared the microbiomes on different parts of their bodies to each other, to each of the different astronauts. And they did find that when people went into space, first of all, some aspects of their microbiomes got more diverse. So they went into space and they picked up a few new bacterial species. And that could have been from the astronauts that just arrived or from astronauts that were on there from the crew before and left some of their microbes behind. Or alien invasive microbes? Probably yes, Daniel. Probably yes. Or no. That voice tells you, Kelly is humoring me.
Starting point is 00:46:24 Well, we at the Whiteson Institute have to have a lot of patience. Wow, you're angling for that patience award, huh? No, Katrina's got it. She's won a 20 years running, let me tell you. That's right. Yes, it's definitely Katrina's. Okay. All right, so they're out there.
Starting point is 00:46:41 They're living together. Obviously, they're sharing the same air. They're using the same bathroom. So all this stuff's going to get intermingled. It makes sense for their. microbiomes to become intermingled. And that is indeed what they found. They found that if you look at their gut microbes over time, they became more similar.
Starting point is 00:46:57 So they had similar species over time. So like some people picked up some bacterial species. Some maybe lost some bacterial species. And so over time, they do start having similar community members that they're swapping. And they think that a big part of why this is happening is because they're all eating pretty much the same limited food options. So, you know, the International Space Station does have 200 different items that you can order, but it's all, you know, it's all pretty similar and has a lot of the same ingredients. And so their gut microbiome is being fed pretty similar stuff.
Starting point is 00:47:33 And part of what you eat supports different members of your gut community. And so they argued that they thought food was driving a lot of this similarity. But also they're sharing an environment in pretty intimate small quarters. I think the International Space Station, you know, if you put two, one, bedroom apartments together. The International Space Station probably doesn't have much more room than that. And there's like, you know, six to ten roommates in there. So it's pretty cramped, lots of microbes. You can't shower. You can, like, wipe yourself down, but you're not, like, you know, really getting a nice shower like you would here at home. But they noted that even astronauts that tended to be working in different parts of the International Space Station and didn't spend a lot of time together still ended up with similar microbes, which is why they thought maybe it had something to do with the food. Even if you're just breathing the same air, isn't that enough? Even if you're not like often touching the same surfaces, it feels like that should be plenty. Yeah, I agree.
Starting point is 00:48:25 They felt like food was pretty important, but I don't see why it wouldn't be, hey, we're touching the same surfaces, and then we touch our food, and that's the kind of, you know, that determines what bacteria are going into our body. And at the end of the day, it's almost certainly not just one thing. It's probably a lot of different things. And have they replicated this kind of environment here on Earth in order to test and to understand how long it takes and under what conditions? Yes. So there have been two, like, year-long analog experiments that they've done here on Earth. There was Mars 500, which was done in Russia. And they looked at how the microbe changed when you have, quote, unquote, astronauts pretending to go on a mission to Mars.
Starting point is 00:49:02 Quote, unquote, astronauts. Wow. Wow. Fire there, Kelly. I don't think that there'd be too much debate amongst the community of professional astronauts, that they are simulation astronauts instead of. astronaut astronauts. But I bet when they introduce themselves, they don't say,
Starting point is 00:49:19 I'm an astronaut, and then they use air quotes. They might call themselves an analog astronaut or something like. I don't remember exactly what the term is. But I think the FAA has a rule where you have to have gone past the Von Carmen line to be called an astronaut.
Starting point is 00:49:36 And so, you know, I think technically I'm not being a jerk. No, but I think using scare quotes puts them in the category of like kids who have dressed up as a quote unquote astronaut for Halloween, not really an astronaut. I see, but only you were seeing the scare quotes. You outed me, but... You said, quote, unquote, astronaut.
Starting point is 00:49:55 Anyway, so these quote-unquote astronaut, should we take them seriously, have done this really incredible thing of living isolated for six months or up to a year. So what did we learn from these studies? They found that the dominant species in the microbiome tended to say the same. So like the species that they had the most of when they went in. in there persisted, but the more rare strains of bacteria that they had when they went into the facility, those tended to become the same. So, like, your dominant bacterial species, that was pretty similar, but some of the, like,
Starting point is 00:50:28 rare ones started to homogenize between the crew members. And for two of them, they changed back to their original state pretty soon after this analog mission was done. And I won't use quotes around missions so that you don't imply that I'm laughing at people. And, all right, and then the other four had a Mars 500-esque microbiome for up to six months. So those changes persisted for them. And the surfaces inside of Mars 500 started to look sort of like the microbiome on the exterior, you know, like the skin parts of the crew, which is something we also see on the International Space Station. And then there was also a study on the Hawaiian space exploration, analog and simulation four mission.
Starting point is 00:51:14 so that's high Cs 4. And they found, and this is gross, that, like, here, let me find the quote, microbial diversity of skin samples from the high C's 4 crew successively increased and showed a delayed longitudinal homogenization with microbial diversity estimates from surfaces, mainly due to complications with the composting toilet. So the point here is that there was. a lot of poop getting on their skin, and so they were seeing evidence of that on their skin microbiome, and that was impacting the results. And space is gross. So this is actually...
Starting point is 00:51:56 The poop to skin pipeline. The poop to skin pipeline. So anyway, composting toilet was getting things pretty gross up in there. Do you think in the high seas they were waking up with poop on their face the way people in Virginia do when they're bitten by a kissing bug? You know, I would bet that L.A. has a lot more cases of kissing bug than all of Virginia. Yeah. So. All right. We're going to look that up and see. We're going to look that up. Sounds good. All right. So the other part of his question was whether this was affected by deliveries or crew changes. So I don't think it's very affected by delivery. So they're pretty careful to sterilize things before they put them in the modules to send them up to space. They're super careful about that, like sterilizing the food and whatnot. And so there's probably not a ton of microbes in there. I mean, it would be amazing to me if there were no microbes in there because, like, you can never get rid of all the microbes.
Starting point is 00:52:44 But I don't think that's a big contributor, and neither did the papers that I read. They didn't imply that was a big contributor either. But there was a study that looked at different surfaces on the International Space Station, and they looked at how the microbes on those surfaces changed over time as crew members changed over 33 months. So crew members tend to change every like three or six months or something like that. And they did see that the bacteria on the surfaces of the International Space Station were changing over time in ways that seemed to reflect changes in the crew. So you'd get a change in the crew and you'd look at their skin microbiome and a few months later the surfaces of the
Starting point is 00:53:24 International Space Station would look more like the microbiome of the crew. And then a new crew would come and that cycle would sort of start again. They had similarity in species, but not necessarily similarity in abundance. So for example, maybe the humans and the surfaces both had bacteria species A, B, C, and D, hypothetical example. But for humans, maybe A, B, C, and D were at abundances of like, you know, 80%, 10%, 5%, and 5% respectively. But on the surfaces, maybe it was something more like 25% for each species. So different abundances, but similar species. So that at least suggests that when a new crew comes, they're spreading their microbe through the habitat and likely to spread that to whoever else
Starting point is 00:54:13 is residing on the station. And something I've learned from our president for microbial research is that the abundance of the bacteria depend essentially on the conditions. Like, are you feeding it the right thing? Is it at the right temperature? And so I wonder if the conditions on the space station are
Starting point is 00:54:28 different from the conditions on the ground in some important way that you would get like the growth of a different bacteria. And the listener asked this great question about zero-g. Does gravity affect the growth of microbes? Yeah. So the listener also pointed out that it's probably a really hard thing to study. And so I'd like to highlight first that, yeah, it's a really hard thing to study. So, I mean, if you're looking at the microbiome
Starting point is 00:54:49 of astronauts, you know, microgravity is changing, but they're also exposed to a little bit more space radiation. They're probably more stressed out than they are on Earth because they have a very packed schedule of experiments and stuff that are super expensive and they don't sleep very well. There's data on that. So a lot of stuff is changing when they're up there. And it's hard to sort of isolate things. Yeah. We have done some studies that suggest that microgravity impacts bacteria in a variety of different ways.
Starting point is 00:55:18 So this isn't talking about microbiomes. This is just looking at bacteria. And they form biofilms differently. So biofilms are when bacteria sort of like adhere themselves together and that makes them a little bit more resistant to the immune system and antibiotics and stuff like that. They also produce different amounts of virulence factors. They have different levels of resistance. to antimicrobials. So we do have some evidence that microgravity impacts bacteria in some
Starting point is 00:55:46 ways, but it's not clear what the impact is on the microbiome. So when you're aggregating all of the bacteria. And I was able to find one study that was starting to try to separate these different pieces. And so what they did was it was a study with rodents where they put the rodents in a harness, where they were trying to simulate lunar gravity by lifting them up so that only like one-sixth of their mass was, like, touching the grounds with, like, they weighed one-sixth as much. And then they also were doing some radiation experiments, and they did find that, like, some community members and the microbiome shifted a bit. But it's kind of hard for me to know if, like, feeling like you weigh less is going to be the same as really being in a microgravity environment and you're in this harness. And that's probably stressful because, you know, the rodents are like, what that?
Starting point is 00:56:36 Why am I confined? I can't move around. It's hard to nail this stuff down. And I wasn't able to find studies that tried to nail it down in humans. There's reason to suggest that the low gravity environment probably is impacting bacteria in a way that scales up to the level of the microbiome. But I think at the moment we don't really understand that. All right. Awesome.
Starting point is 00:56:55 Well, that's a fascinating look at microbiomes in space and the life of astronauts. Let's send this answer over to our president for microbial research and hear what she has to say. And let's hear what John has to say. Absolutely. Oh, I'm worried about what Katrina has to say. I hope I got it right. So Katrina, what did you think? Well, I have to say, I was playing in my mind the studies that Kelly brought up, like, seconds before she said them.
Starting point is 00:57:24 So that was very satisfying. So nice job with your research, Kelly. In some cases... That's some real approval right there from the president. In some cases, those are, like, talks I have seen, like, I met the scientists who led the study. So, for example, the microgravity studies with the bacteria showing the changes in biofilm formation and virulence factor expression, I met a scientist who led a study like that. It was published in nature gravity, and she had these crazy contraptions where they would
Starting point is 00:57:57 kind of like at the at an amusement park where they like spin you in circles and then there's less gravity. They did that to the microbes. So she was conducting those experiments on Earth, but changing the gravity that the microbes felt. And so that was a cool way that those experiments were done. And yeah, I think there are changes that we've only studied at the smaller scale, and we don't know how they synchronize up at the bigger scale, which I know is a real theme for you guys. So, you know, does one microbe by itself when put together with 10 to the 29 microbes, as they're like a new simplicity that emerges? I don't
Starting point is 00:58:28 know. And then just on the space analog front, I'm, I also, I was really interested in that for a long time. In fact, I wrote proposals to the Australian Antarctic Division many times with the hope of studying the Australian Antarctic researchers who live on some of the most isolated bases down in Antarctica. Sometimes only like 10 people will spend the whole winter eight months together with no new shipments coming in. And so it's a way of learning about people in close quarters and experiencing stress that's similar to what astronauts experience minus the whole gravity thing. And I think they have a little more access to fresh air, for example. But anyway, I never did get the proposal to do that.
Starting point is 00:59:14 But I think it's really interesting. They have definitely seen changes in how your immune system is functioning. And just keep in mind that your microbes and your immune cells are a big, there's a lot going on with the interactions between the immune cells and the microbes. So as stress and environment changing your immune system changes, that's a big pressure that will influence which microbes can thrive in your body. So I'm very sure that's a big part of how the microbiomes change. And all around, I think, yeah, it's just about exposure to the microbes from other people around you and the conditions like the food will also have an impact. but it's like you need the microbes and the nutrients together to shape the community.
Starting point is 01:00:00 So I'm sure both of those forces are really important. I actually also recently saw a NASA scientist give a talk about contamination from even astronauts wearing their spacesuits going out on like spacewalks and on the surfaces of the International Space Station, for example. And if you take swabs out there, you find that there are microbes, being dribbled, which is like there's a real goal of the whole space community to avoid contaminating the universe with our Earth's microbes. And that's a really big challenge.
Starting point is 01:00:36 So even the spacesuits, which are pretty well contained, do not entirely prevent microbes from dribbling out. So if we went up to Mars, I mean, this is obviously, I have no idea when we might be doing this, but if we were to send people in spacesuits up to Mars to sample the rocks and try to learn about life, we would have a hard time not contaminating with our own microbes. And a lot of our methods are, you know, for low abundance, low biomass samples, they are right at the limit of detection. So it starts to become impossible to distinguish what's showing up in the kit reagents versus what's actually coming from the environment that you're sampling. So those are the things that the
Starting point is 01:01:16 space microbiology community are thinking about, I think. So what grade would you give Kelly? Oh, my gosh. I mean, 100%. Maybe actually A-plus. All right. Good job, Kelly. Hello, Daniel and Kelly. Yes, you answered my questions. The most interesting point being that the major compounds of people's microbiomes remain stable under such close and isolated conditions. The immediate follow-ups that came to mind were whether the same effect was visible on the surfaces of the ISS. Thanks. Hey, John, great follow-up question. the microbiome on the surface of the International Space Station, like, you know, the various computer screens and stuff like that, do tend to change over time in ways that reflect the
Starting point is 01:02:00 makeup of the crew that's on the International Space Station. So there's a lag between new crew members coming on and all of the microbes that are covering their hands and their arms sort of getting on all of the surfaces. Thanks, John. All right. Thanks. everybody for these wonderful questions. We thoroughly enjoy these discussions and give us the opportunity to dig deep into a question we have sometimes wanted to understand better ourselves. So thank you very much for sharing your curiosity. Remember that science moves forward because of human curiosity and that includes you. So send us your questions at questions at
Starting point is 01:02:40 Daniel and Kelly.org or you can join us on our Discord channel. You can find an invitation to our Discord channel on our website, Daniel and Kelly.org. Or follow us. on Instagram, Twitter, or Blue Sky at D&K Universe. Have a great day, everyone. Hi, Kyle. Could you draw up a quick document with the basic business plan? Just one page as a Google Doc and send me the link. Thanks. Hey, just finished drawing up that quick one page business plan for you. Here's the link. But there was no link. There was no business plan. I hadn't programmed Kyle to be able to do that yet.
Starting point is 01:03:16 I'm Evan Ratliff here with a story of entrepreneurship in the AI age. Listen as I attempt to build a real startup run by fake people. Check out the second season of my podcast, Shell Game, on the IHeart Radio app or wherever you get your podcasts. Is she said, Johnny? The kids didn't come home last night. Along the central Texas plains, teens are dying. Suicides that don't make sense. Strange accidents and brutal murders. In what seems to be, a plot ripped straight out of Breaking Bad. drugs, alcohol, trafficking of people.
Starting point is 01:03:51 There are people out there that absolutely know what happened. Listen to paper ghosts, the Texas teen murders, on the IHeart Radio app, Apple Podcasts, or wherever you get your podcasts. Michael Lewis here. My best-selling book The Big Short tells the story of the build-up and burst of the U.S. housing market back in 2008. A decade ago, the Big Short was made into an Academy Award-winning movie. And now I'm bringing it to you for the first time as an audiobook narrated by yours truly. The Big Short Story, what it means to bet against the market, and who really pays for an unchecked financial system, is as relevant today as it's ever been.
Starting point is 01:04:32 Get the Big Short now at Pushkin.fm. slash audiobooks or wherever audiobooks are sold. You know the shade is always shady. It's right here. Season six of the podcast Reasonably Shady with Giselle Bryan and Rysail. Robin Dixon is here dropping every Monday. As two of the founding members of the Real Housewives Potomac were giving you all the laughs, drama, and reality news you can handle. And you know we don't hold back. So come be reasonable or shady with us each and every Monday.
Starting point is 01:05:05 Listen to reasonably shady from the Black Effect Podcast Network on the IHeart Radio app, Apple Podcasts, or wherever you get your podcast. This is an IHeart podcast. Guaranteed Human. Thank you.

There aren't comments yet for this episode. Click on any sentence in the transcript to leave a comment.