FoundMyFitness - #105 Exogenous ketones, my coffee protocol, and supplements for blood sugar regulation (Premium Member Q&A July 2025)
Episode Date: August 5, 2025Become a FoundMyFitness Premium Member to access the full episode In this special episode, you'll get an exclusive 30-minute preview of my latest Ask Me Anything (AMA) session, normally reserved for ...FoundMyFitness Premium Members. Each month, Premium Members join me live to receive direct answers to their most pressing questions on nutrition, supplements, longevity, sleep, fitness—no topic is off-limits. In today's sneak peek, you'll hear why I've started taking exogenous ketones, details about my personal coffee routine (from bean choices to brewing methods), optimal supplement dosages (including ubiquinol, berberine, and vitamin K2), and whether some popular greens powders might pose risks due to heavy metals. Learn more here about becoming a FoundMyFitness Premium Member for as little as $15 per month. After signing up, you'll also unlock the full 90-minute session, along with more than 100 hours of additional AMA content. Your membership directly supports our mission to deliver trustworthy, unbiased, science-backed health information that's entirely ad-free and free from commercial bias. Every Premium Member helps us stay focused solely on providing you with the highest-quality insights grounded in rigorous science. Timestamps: (00:00) Introduction (02:44) Why I started taking exogenous ketones (04:02) What ketone supplement brand am I using? (07:16) Can ketones help reduce performance anxiety? (08:50) My daily coffee routine (beans, brewing, and tips) (11:31) Should you worry about diterpenes in coffee? (12:56) Which coffee bean brand do I trust most? (14:04) Does coffee cause dehydration or block mineral absorption? (15:46) Is drinking coffee on an empty stomach harmful? (16:01) Does dairy reduce coffee's polyphenol benefits? (17:53) Should slow caffeine metabolizers avoid coffee? (18:52) Can coffee's vasoconstriction affect brain blood flow? (19:18) Do coffee pods release harmful microplastics? (20:09) The ketone meter I've relied on for 10 years (20:35) Does quitting caffeine lower resting heart rate? (20:41) What's the best plastic-free coffee maker? (21:13) Ideal dosing for ubiquinol, berberine, and alpha-lipoic acid (22:43) Which supplements best support fertility and egg quality? (23:49) Why (and how much) myo-inositol did I take? (24:08) Am I still taking benfotiamine, collagen, lutein, and zeaxanthin? (24:34) Creatine vs. methylated B vitamins for homocysteine control (25:56) Which vitamin K2 supplement (and dosage) do I use? (26:17) Are greens powders (like moringa) high in heavy metals? (27:16) Which choline supplement won't raise TMAO? (30:31) Which Thorne supplements do I personally use? (30:44) How much CoQ10 is needed if you're not targeting fertility?
Transcript
Discussion (0)
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Hi, everyone.
Welcome to Q&A number 72.
Nice to see people from all around.
I see people saying hi from their location.
Excited to be here.
Today, we're going to do things a little differently.
I'm going to start with the rapid fire questions that I usually end with.
And then after the rapid fire questions, I'll kind of get into some deep dive questions today.
But I did mention in the chat.
that I was going to get my exogenous ketones and I see some questions already in the chat about
exogenous ketones and the different types of ketones, when to take them and why. And some of you
may be wondering why I'm taking it right now. I didn't get to do any of my high intensity interval
training this morning. And that usually gives me a pump of lactate. And that lactate gets into
the brain and it really sort of gives me a little extra pump so that I can, you know,
feel cognitively ready to do this Q&A. And so I took my exogenous ketones because beta hydroxybutyrate,
which is the major circulating ketone and it's the one that's found in all these exogenous
ketone products, is acts very similar to lactate in the sense where it activates a lot of the same
genetic pathways, including brain-derived neurotrophic factor. It's also anxiolytic. So what I find
when I take some exogenous ketones is that I feel, it's not the same as like drinking a cup of
coffee, but I feel focused, but a very calm focused. So it seems to calm me a little bit and
allow me to focus better. And I really like that. So when it comes to the type of ketones right now,
I don't have any affiliation with any brands, but I've been experimenting with Delta G, and this is what's known as the Oxford ketone.
It was developed by Dr. Richard Veach and Kieran Clark, who is at Oxford.
It's the real deal.
It's the ketone that was sort of developed with funding from DARPA, and it was really the aim was to kind of help military personnel.
be able to be cognitively on their game during very stressful periods where they're
sleep deprived, perhaps not eating under a lot of just stressful conditions. And so
that is the ketone I'm doing. And the reason I'm experimenting with that one is because
it's the only, well, actually there's the Oxford ketone is the only ketone out there that
actually is the beta-hydroxybutyrate ester. That one and also ketone,
aid, which was started by Richard Beach, that one also uses the same ketone ester. So what that is
is the beta-hydroxybutyrate, and it's esterified to 1-3 butane diol. What that is, is it's an ester
that your liver does get, your liver converts into beta-hydroxybutyrate eventually. So what
happens is when you take a product like Delta G and I'm using their Delta H product because it's the
I don't really need the really, really high ketones. So this is about 11 grams of ketones in a serving
size of a bottle. And they have higher, higher dose ones. It's like 25 grams. And I don't,
I don't really need that. So you feel the effects immediately because it does have beta hydroxybeterate
in there without having to be converted into beta hydroxybutyrate by your liver. So you feel the effects
immediately within like minutes. And then because it's esterified to the 1-3-butane dial over the course
of an hour to 90 minutes, you're also converting, you know, that 1-3-butan dial into more
beta-hydroxybutyrate. And so it's sort of not only do you have an immediate effect,
but you have this sort of long tail effect as well. Now someone asked about ketone IQ. That product
only uses the 103 butane diol. So there's no actual beta-hydroxybutyrate in that product.
It's a much lower dose. I believe it was five grams. And it's also slow acting. So if you want that,
if you're using that for something like in my case where I'm giving, you know, doing a Q&A or let's say I was, you know, I'm doing a podcast or a talk,
then I would take it at least an hour beforehand because it takes a while to convert the
1-3-butane dial into the beta-hydroxybutyrate. You can kind of think of it as like a precursor,
ketone precursor. Whereas the one I'm taking right now, I can just take, boom, right away. I'll
feel it immediately, and then I continue to feel it over the next, you know, a couple of hours.
It's also given me a little bit more motivation to revisit my experimentation with ketogenic diet,
certainly cycling. I like the way I feel. I like the calming effect and that largely has to do with. I had a
podcast with Dr. Mark Mattson, you know, a few years back and and he was explaining, you know,
when you're in ketosis and your body is making beta-hydroxybutyrate in ketones, it,
the beta-hydroxybutyrate appears to, it gets into the brain and it short, it sort of shifts the
balance between GABA, a neurotransmitter, inhibitory, nerve,
neurotransmitter and glutamate, which is more of an excitatory neurotransmitter.
And it tips the balance more towards GABA.
And that sort of has this anxiolytic effect where you feel calmer and you're less anxious.
So for me, that is hugely beneficial because I do sometimes have an amount of background
anxiety, particularly if I have to perform.
And so I like that sort of calm focus that I feel when I have, when I'm either in ketosis
because I have experimented with ketogenic diets.
And I do remember that being one of the most profound effects that I noticed when I was doing
a ketogenic diet.
And also I've been in ketosis from fasting, same thing.
And then I've tried exogenous ketones.
And so they all sort of replicate that feeling of sort of calm,
focus, which I do really like. I see people in the chat asking Faisal's asking about advice on sleep
and shift work. We are going to do a little bit of a deep dive on sleep today, so we'll talk
more about that later. I want to go ahead and get some of the rapid fire questions.
I love how a lot of people asked questions, follow-up questions on my recent coffee episode that I
released. I don't know, a few weeks ago.
So Ruby asks, follow up on a great coffee episode. Do coffee filters have any sneaky
chemicals or glue in them? Yes, some of them can. I use the, the Kimex unbleached coffee filters.
Those are the ones that I use. I really like them. If you want to try them out, great.
A related question for Michelle was, loved your deep dive on coffee. What brand and type of
coffee maker, filter, and coffee do you use? And are you saying that a
paper filter does remove all the bad stuff that you mentioned. Okay, so the coffee that I have been on,
I've been using right now. I've tried a lot of different brands. And honestly, right now,
I'm on a bit of a decaf coffee kick because my creatine is amazing. And now that I take 10 grams a day
instead of five grams a day, I find that I'm not having that afternoon crash.
I don't want to say I want to call it a crash because I wasn't really crashing.
But I would often get a little sleepy, you know, two, three o'clock in the afternoon.
I no longer have that with my higher dose of creatine.
And so I've also gone down to decaf.
and the brands that I use for both decaf and also regular caffeinated coffee, because I'll cycle back on.
And the great thing about cycling off of coffee and then going back on is that when you go back on, the coffee is so effective.
And so I like to use it for those moments when I really need it.
I use the purity coffee brand.
I really like their organic coffee.
For the decaf, I use their calm decalf, which is great.
They have regular coffee, which is also great.
and so right now that's kind of like my brand that I've been using.
I already mentioned the filters I use, the KMEX unbleached coffee filters.
And then for a coffee maker, I like doing the pourover.
And so I do Kemex pour over glass coffee maker.
So it's like a big glass coffee maker.
And then you put the filters inside and the coffee and then you pour the hot water and then there it goes.
It drips through.
When it comes to the filter, it does filter out a lot of the oily substances,
the diterpenes, which I know I kind of painted a bad picture of in the episode because they
raise LDL cholesterol, and that could be a concern, particularly for people that already are
higher risk for, you know, dyslipidemia. Perhaps they have higher LDL cholesterol. They have higher,
maybe they have LP small A. There's a ton of reasons why someone may want to really just be very,
you know, anal about making sure that they eliminate all the things that can raise their
LDL and try to keep that down. But the dieterpenes also, there is at least some in vitro evidence.
So this means these are just cells in a petri dish. It's not the strongest type of evidence,
but it is still something to talk about that there can be some anti-cancer effects with the
the diterpenes. So they're not all, it's not like they're just like villain and there's nothing
good about them. There is potentially something beneficial, although we don't have a lot of evidence
to support that. It does seem like there's a possibility that there's some benefits there as well.
In other words, what I'm saying is if you like your French press coffee, by all means,
keep making your French press coffee, particularly if your LDL and lipids are looking great.
And we're going to talk about lipids as well today. A related question from Freda Vera.
they ask, what's the best overall company to purchase organic beans for cognitive protection?
Again, I'm turning to purity coffee because one of the reasons I really like their brand is they have a lot of testing and data posted on their site.
They sort of validate the organic beans.
They do independent analyses on, you know, the polyphenol content.
So this would be the chlorogenic acid.
and it seems to be pretty much like, you know, a really high, high amount of the chlorogenic acid.
In fact, their light to medium roast preserves around 65% more of these polyphenols than other
organic brands do.
And they also have third-party testing showing that they're free of pesticides and heavy metals
and other contaminants.
So I like that brand.
And again, the polyphenols are really what is beneficial for brain health.
Again, caffeine itself also appears to be beneficial.
So I'm on my decaf kick right now, but I will shift back to my caffeinated coffee eventually.
Okay, and then another related question on coffee was from KRD, who says,
Hi, Rhonda on the subject of coffee.
What does the research say about coffee causing loss or malabsorption of minerals, such as iron or zinc or copper?
Also does coffee cause dehydration?
In what way can we drink coffee to prevent nutrient loss?
So with respect to nutrient loss, coffee really most people are fine.
I would say it's very minor.
And the biggest minor effect would be iron.
So even most people that have normal amounts of iron don't have to worry about this.
But it can, you know, cause a little bit of an absorption issue with iron.
And so if you are eating a meal, you probably want to make sure.
sure it's like the coffee spaced out by like an hour so that you're not inhibiting the absorption
of iron from your meal. When it comes to dehydration, it's totally like it's just not,
it's kind of unfounded, basically, especially for people drinking normal amounts of coffee.
And you start to get into like the really high dose. Maybe you can cause some issues, but
there was a study showing that, you know, four 200 mil cups of coffee per day. And
You know, so this is about four milligrams of caffeine per kilogram body weight per day.
Over the course of 72 hours, there was no difference in terms of water, total body water and urine, osmolarity, just all that stuff.
So there's really just not a lot of evidence that it's causing dehydration in most normal circumstances.
Another rapid fire question from Farid Gargor.
They ask if there's any issues of drinking coffee on an empty stomach.
not that I'm aware of. I mean, obviously, like, maybe some people do, but I don't, there's not
like an overall thing. It's not like a thing. And then another question about dairy. So the question
is regarding the dampening effect of dairy, if my goal is general long-term health, is there
still a benefit to avoiding dairy in order to maximize immediate absorption of polyphenols?
Would it in fact be better to add dairy and slow the absorption rate? So what, what the
this question is hinting at is the fact that coffee, when you add dairy to your coffee,
you are not, the bioavailability of the polyphenols is dramatically slowed. In fact, there was a
crossover study that gave people 609 milligrams of chlorogenic acids. Those are the major
polyphenols found in coffee plus whole milk. And they found, you know, that basically the metabolites
that are the polyphenol metabolites, they fell from 68 to 40, and it was about 40% relative drop in
the first day of recovery. So essentially, you're not going to get all those polyphenols
popping, like, immediately, but eventually they catch up. So over long-term health, it's fine,
but if you're wanting that immediate polyphenol boost to your brain, then you probably
should not add dairy. You should do something like MCN.
CT powder or, you know, some kind of plant milk, like almond milk, for example, and if you like
to have your coffee with cream, don't use dairy. And then there was another related question about
protein doing something similar. And yes, it does do something similar. And you can essentially
just time your protein 30 minutes before or after your coffee if you're concerned about the
delay and biobelial release and bioavailability of polyphenols. And there was. And there was,
was another, this is the last question on coffee. This question was submitted by Sam and Sam says,
for those of us who have the gene for slow metabolism of caffeine, should we do anything
differently? Your gene data notes that slow metabolizers should limit or avoid caffeine altogether.
Is this still valid? I would say that for people that are slow metabolizers, obviously you need
to kind of self-experiment, but typically you want to limit your caffeine to like more
use and like you you know taking it in the afternoon maybe the issue because if you're are if you're a
slow metabolizer it may take you know 10 10 to 12 hours before you're metabolizing all that caffeine
and so there may be this residual effect on your sleep however you should be able to mostly notice
that so if your coffee consumption protocol is not causing any issues with your sleep then whatever
you're doing should probably be fine okay this there's a
a few more rapid fire questions we're going to get to before, but I want to look at the chat
to see some coffee-related questions here. Mirna is asking about my thoughts on decreased blood flow
from basal constriction from coffee to the brain. In fact, the polyphenols do the opposite. They actually
increase the blood flow to the brain, so whatever minor baser constrictions probably just canceled
out. Bode's asking about
nespresso virtro
virtro. Sorry, I don't know how to say that, but the
nespresso capsules. And they're
asking where this falls on the health
spectrum.
Unfortunately, those
pods, those capsules, they're all
they all like have lined plastic
in them. And so
my biggest concern with those
isn't the coffee type. It's
the hot liquid going
through plastic, which as we have
talked about several times, rapidly accelerates the breakdown of microplastics into your
beverage, as well as their associated chemicals like BPA into your beverage. Unfortunately,
I don't think those are a good choice for that reason because you're actually going to be
consuming a lot of microplastics and plastic associated chemicals.
Alyssa is asking about the meter I use for my ketone to measure my ketones. I actually don't
use the meter that's sold with any companies. I use a precision extra, which allows me to measure my
blood glucose with a finger prick or ketones or I don't know if they do lactate. I use a different
meter for lactate. But I really like the precision extra. I've been using it for like almost 10 years.
It's a really great product. Mike is asking when I cycle off caffeine if I notice any lowering in
my resting heart rate. Actually do not. Monica's asking about coffee pot makers that are not made of
plastic. That's why I mentioned the one I use, which is the glass chemex, and it's a pourover.
And so it's basically you just put the filter on the top of it and then the coffee drips through.
And then, of course, there's some percolators that you can buy that are not made of plastic.
And there's the French press, of course, as well if you're not concerned about drinking unfiltered coffee.
Allie's asking about coffee pods that are compostable and made of paper.
As long as you can confirm there's no plastic lining inside the paper, then sounds great.
Okay, let's finish up some of these rapid fire questions that were submitted.
Chris Hall asks, you recently mentioned the potential benefits of ubiquinol, berberine,
and alpha lipoic acid in synergy.
Can you speak about appropriate dose ranges?
So for people that are really wanting to not only affect their glucose regulation,
but also their lipid panel, their, I would say, you know, their lipids, they're wanting
to optimize their lipids in general.
then I would say that the literature really suggests berberine in a higher dose is more beneficial and
it has to be split up. So the studies really do highlight that berberine should be taken at about
600 milligrams three times a day and it's taken with meals. If you're wanting it to really
affect the glucose response and needs to be taken with a meal. And so that's a total of about 1.8 grams a day
of berberine. Lalfilipoic acid is anywhere between 600 to 1,200 milligrams a day. And the ubiquinol
is a reduced form of co-Q10, co-cue enzyme 10. And essentially, the ubiquinol is a more
bioavailable form. So, and I talk about this in a minute in the context of fertility, which is a
little bit of a higher dose. But in this regard, you know, 100 milligrams could be fine. Okay,
here's the related question about ubiquinol and the optimal dosage for a woman in their mid-30s.
That's preparing for egg freezing or improving mitochondrial health. So those studies actually
show 600 milligrams a day of CO-10 in the form of ubiquinone, which is the oxidized form
of COQ10 and it's less bioavailable. So modifying the dose here, if you're looking at the more
bioavailable form, the ubiquinol, 400 milligrams a day of that is also something that would be more
equivalent to the 600 milligrams a day of the COQ10. Some other things to add for women that are
looking to improve their egg quality, that they'd obviously want to add a prenatal vitamin that has
all those important B vitamins in it. And the methylated ones is,
well you want to add vitamin D, 5,000 I use a day, you want to add omega-3, about 2 grams a day.
Also some evidence that melatonin 3-migs a day has antioxidant effects as well on eggs, and then
myoanositol about 4 grams a day as well. And this leads into a related question by Ivana about
myoanositol and what the dose is and the reason I'm taking it. So I was taking it again,
four grams a day and mostly it was for sleep but also for ovarian reserve and then karen says in your in your
in your june supplement update you didn't mention taking benphotamine collagen lutein or zazanthan
are you still taking these if so when do you incorporate them i do take collagen every morning
in my coffee lutein and ziazanthin are in my multivitamin so um i don't feel like i need to take
those really separately and then benphotamine
I haven't been taking lately.
There's another question from Matthew Tanner asking about homocysteine.
I don't seem to talk about taking extra methylated B vitamins.
So, yeah, my homocysteine is gray.
I don't really take care.
I don't really take extra methylated B vitamins because I get it in my multivitamin.
But, and then I also am taking creatine and creatine.
creatine has been shown in some studies to improve homocysteine because creatine is a major, major, major,
sink for, let's just call it methylation groups.
In other words, it takes a lot of these methylation groups to make creatine.
And so that sort of takes away from the other roles that it could play, like lowering homocysteine
because you need methyl groups to convert homocysteine back into methionine, right?
And so if you're freeing up methyl groups because you're giving your body exogenous creatine,
then what happens is those methyl groups can then be used to methylate homocysteine and then
thus converting it into methionine.
Not a lot of people talk about this, but there is some evidence on it.
And again, I do take 10 grams of creatine a day.
Stass asked what vitamin K2 supplement I'm taking.
I'm actually taking the, I'm now taking the pure encapsulations.
They didn't always have this.
Pure encapsulations, vitamin D plus K2.
That's my new supplement.
So it's all in one, which is great.
And you guys know I don't have any affiliation with peer encapsulations.
Okay.
we're almost done with these rapid fire questions. Kathy asks, my question is that Rhonda told us a lot of great
things about maringa powder by Kooly Kooley a while back, but she's now saying there's a lot of lead
in powder in powder green supplements. Is there lead in Moringa powder? Is Ronda still taking Meringa
powder? So I do not currently take Moringa powder. I have switched to supplementing with Avicol.
I think I told you guys this. I take the extra strength of macal. It's really,
fantastic. It's helped my mom with her tremors. It's kind of amazing. I've moved away from any
sort of green powder supplements because I do, I do think that they're just a high risk for
heavy metals. You can test this. There's a variety of blood tests that you can do, add back
in some green powders, and you might see that your heavy metal burden goes up. So that's kind of
what I'm doing right now. And then this is the last rapid fire question from Ted Ham. And Ted
asks, what are the best options for colonel supplementation if one has SNPs for poor
phosphatidal colon absorption or levels given the risk increase in TMAO levels? Now, keep in mind,
coaling deficiency also leads to non-alcoholic fatty liver disease. And so you want to be
careful with that as well. So the free coline salts are the forms that the gut, the microbes in the gut
can actually ferment into TMAO. Well, it actually ferments it into trimethylamine and then that gets
formed, that gets converted into TMAO, which is pro-athrogenic. And that's what people are wanting to
avoid. So essentially, the goal would be to not have coline in this salt form.
you'd want coline and it's already sort of preformed membrane-ready part.
You know, so in this case, you'd actually want to supplement with the phosphatidal
colon because you wouldn't, the microbiome, the bacteria in the colon wouldn't really be able
to use that phosphatidal chlorine, that colon that's already in this membrane as a substrate
to make the precursor for TMAO.
So, in fact, there was a study that looked at phosphatodal coline capsules for four weeks,
and essentially the TMAO was unchanged.
So it wasn't increasing the TMAO, whereas the same dose of coline by tartate, by tartrate,
so that would be the colon salt, did increase TMAO quite sharply, actually.
So I think the solution here really is you want to do phosphatotidol,
coline. Another potential form would be the citicoline. So this is CDP coline. And this is basically
it's a nucleotide. It's a nucleotide bound coline. And I don't think it's very, it's much more
less prone to converting the colonel into the TMA or the TMAO. So that's another form of
coline. I've actually been experimenting with that recently because it's a little bit of a
neutropic because colonelchloric, which is a precursor for acetylcholine, which is a neurotransmitter
that is involved in cognition memory. So cytokoline would be another form. But I would say for the
purposes of wanting to get, you know, not the neutropic effect, but wanting to get like
adequate amounts of chlorine, phosphatyl colonel colon would be the way to go. Matthew's asking if I
have any concerns with the coline by tartate in the multi? No, because it's such a small amount.
We're talking about, we're talking about levels that are much, much, much higher.
You know, 250 to 500 milligrams. You know, so it's a very, very different amount that we're
talking about here. When it's a super small amount, it's just sort of, it's non-significant.
Faisal is asking if I have any opinion on thorn products. I use a lot of their supplements.
I use their creatine.
I use their glutamine.
I use a lot of their supplements as well.
I think they're a good brand.
Daisy's asking if we take KU10 and not looking to get pregnant, do we need 600 milligrams a day?
No, you do not.
The 100 to 200 is fine for mitochondrial health.
The 600 milligrams is an excessive amount and it's solely for the purpose of increasing the egg quality, the ovarium.
reserve. So really, it's a very specific outcome that people are looking to achieve when they're
supplementing with a high dose of co-cutin and or ubiquinol. Let me get to the deep dives.
Okay, so the first question, this was a top-voted question by Alina. And the question is,
what are the most common causes of fragmented sleep and nighttime awakenings that last over an hour?
and which strategies or nutrients do you recommend to improve sleep, continuity and depth?
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