Global News Podcast - Trials of new Ebola vaccine set to begin

Episode Date: July 13, 2026

A new vaccine to tackle Ebola will now be tested on people after the UK regulator gave permission for trials to take place. University of Oxford scientists began developing the vaccine - aimed at tack...ling the Bundibugyo species of the virus - eight weeks ago, when a public health emergency was declared by the World Health Organization. It is the first - out of four vaccines under development - to enter clinical trials. The epidemic, centred on the Democratic Republic of the Congo, has killed more than 700 people. Also: the dispute over who controls the Strait of Hormuz has intensified with some of the heaviest exchanges of fire since the US and Iran agreed an interim peace deal last month. The Spanish prime minister, Pedro Sánchez, has visited the wildfire zone in the southern province of Almería, where 13 people have died. Almost 3 million people in China have been evacuated from their homes as a result of Typhoon Bavi. The actor Sam Neill, known for films such as Jurassic Park and the Piano, has died at the age of 78.The Global News Podcast brings you the breaking news you need to hear, as it happens. Listen for the latest headlines and current affairs from around the world. Politics, economics, climate, business, technology, health – we cover it all with expert analysis and insight. Get the news that matters, delivered twice a day on weekdays and daily at weekends, plus special bonus episodes reacting to urgent breaking stories. Follow or subscribe now and never miss a moment. Get in touch: globalpodcast@bbc.co.uk Photo: Researcher Alex Sampson holds the experimental Ebola vaccine Credit: BBC/TREVOR LLOYD

Transcript
Discussion (0)
Starting point is 00:00:00 This BBC podcast is supported by ads outside the UK. Your sales order says one thing. Your inventory says another. Your spreadsheet says, good luck. Odu brings your business together on a single platform, from sales and accounting to inventory and marketing. Visit Odu.com to book a demo. It's ODbolo.com.
Starting point is 00:00:23 My name is Shannon Maldonado. I'm the founder of Yowie, a gift shop from the lens of artists and handmade objects. I chose Shopify because when I was testing other platforms, it was definitely one of the most user-friendly. It was important to me to think about where we would be in the future. All of the tools for reading your sales like planning inventory, they're just right there on your dashboard. For anyone starting a small business, the biggest thing I can tell you is it doesn't have to be perfect. Shopify can help you build upon it. Start your free trial on Shopify.com.
Starting point is 00:00:53 This is the Global News Podcast from the BBC World Service. Hello, I'm Oliver Conway. We're recording this at 15 hours GMT on Monday the 13th of July. Britain approves trials for a new vaccine to tackle the worsening Ebola outbreak in the Democratic Republic of Congo. President Trump says the US will reinstate its naval blockade of Iran. And Ukrainian attacks cause trouble for drivers in Russia. Also in this podcast?
Starting point is 00:01:22 You've got this network of spies operating under Japan's nerves. and Japanese manufacturers' parts repeatedly turning up on the battlefield in Ukraine. The New York Times says Russia is taking advantage of weak espionage laws in Japan. In May, the World Health Organization declared the Ebola outbreak in the Democratic Republic of Congo a public health emergency of international concern. Now, the Congolese authorities say it has spread to two new provinces, but efforts are underway to fight back. Regulators in the UK have approved trials of a new vaccine,
Starting point is 00:01:59 vaccine that's been in development since that WHO declaration. It's one of four aimed at countering the Bundy-Budgio species of the virus, but the first to enter human trials. Alex Sampson is one of the researchers at Oxford University. The way we've been able to make this vaccine so quickly, there's a few reasons. One of these is that we're using the same vaccine technology that we use to make the Oxford Astrozenica COVID vaccine. We've also got a lot of experience in the team, both using that platform and working on vaccines against different Ebola viruses. So because of that combined experience, we were able to respond really, really quickly. I got the details from our medical editor, Fergus Walsh.
Starting point is 00:02:35 They're using the same vaccine technology that was used during COVID. Hundreds of millions of people had the Oxford Astrosenica COVID vaccine. It starts with a disabled common cold virus into which you put a scrap of genetic material. In COVID, it was the spike protein. And with this, it's a tiny, the only surface protein. on the Bundy-Budjo Ebola species of a virus and goes into the body inside this virus and is delivered to cells,
Starting point is 00:03:09 prompts them to start making this scrap of genetic material. That prompts an immune response to produce antibodies and T cells so that hopefully should the person then come into contact with Ebola at some time in the future, they'll be protected. Now, obviously these volunteers won't be given Ebola, it won't be a challenge trial, but their safety and the immune response that is produced will be monitored to see what level of immune response it produces. When will they know how effective it is? And if it is effective, when could it be actually
Starting point is 00:03:45 seen in use in places like Congo? Within a few months, I mean, this trial, they'll actually monitor them for a year. there'll be another small trial which will start in Africa probably a few weeks later. I think the first doses of this vaccine, and they're looking for 50 healthy volunteers in Oxford, age 18 to 55. There'll be a similar small trial in Africa, which will start a couple of weeks later. Then they'll have to be a larger trial in situ in Africa, which will be in the affected areas. But I think we're talking about in months. And already the Serum Institute in India, which worked with the Oxford team during COVID,
Starting point is 00:04:31 they have speculatively produced more than 600,000 doses of this prototype vaccine. They've got them stored ready for potential use. So they've done everything consecutively here so that what used to take months and years, the delays between one trial and another. They all happen pretty much overlapped so that they're ready to go. And obviously there's a massive need for this latest figures today, more than 700 deaths. This Bundy Bujo strain kills about one in three of those infected. If it is rolled out, of course, it will be hard to get it to everyone
Starting point is 00:05:09 because there is a lot of scepticism and also the conditions are difficult in Congo. Yeah, it's a fragile area affected by war. They've got limited healthcare facilities, a lot of. movement, displacement of populations, and a lot of distrust of healthcare and officialdom. So it's going to be tricky, but government workers and agencies are doing their best there to try to ensure that they bring the local communities on board here because it's absolutely vital because this is such a deadly virus. Our medical editor, Fergus Walsh.
Starting point is 00:05:45 Just before we began recording this podcast, President Trump announced that the US was reinstating its naval blockade on Iran. The dispute over who controls the Strait of Hormuz has intensified, with some of the heaviest exchanges of fire since Iran and the US agreed an interim peace deal last month. In his social media post, President Trump declared the strait was open to other countries safeguarded by the US, but there would be a charge of 20% on all cargo shipped, effective immediately. Earlier, Iran carried out a barrage of attacks against U.S. military assets in the Middle East after the Americans targeted Iran overnight. I got more details from our correspondent in Jerusalem, Barbara Plattusha.
Starting point is 00:06:27 As you mentioned, the Iranians have begun to retaliate for the U.S. strikes. They have targeted U.S. assets in Jordan and Kuwait. Both of those countries say they have been intercepting incoming fire. There's also been reports from Bahrain that air raid sirens have gone off there, That seems to be what the Iranians are focusing on, again, retaliating for the U.S. strikes overnight, which were the Americans, say, aimed at trying to degrade Iran's ability to attack international shipping in the Strait of Hormuz. All of this triggered from attacks on ships that began last week. And so this is now the fourth round of retaliatory strikes.
Starting point is 00:07:07 The Iranians have not said very much about what was hit in the country. They said there were targets in the south and west. They did say one person was killed and four injured. And the Americans have said they've been targeting things like radar stations and drone and missile sites and so on. But that has not so far prevented the Iranians from being able to, from time to time, fire at the ships in the strait. Now, the oil markets initially seemed to shrug off the various ceasefire violations
Starting point is 00:07:36 from both Iran and the US. But this is now starting to look a little more serious. It's beginning to look a little bit more. permanent, if you can put it that way. Permanent's probably not the right word, but it does look as if it's something that is not going to go away because the interim deal between the U.S. and Iran was supposed to open the strait to international shipping,
Starting point is 00:07:58 and then they were going to go on and talk about other issues that could end the war, sort of bring an end to the war permanently. But instead, the Strait of Hormuz has become this major sticking point, and the dispute over it has basically stalled any progress on the deal, and it means that the ceasefire has been unraveling. So it's not believed at this point yet anyway that either side wants to return to a full-scale war. But this issue, this control of the strait,
Starting point is 00:08:25 this freedom of shipping through it and so on, is just very crucial to both. So what we have now is continued escalation. Barbara Plet Usher in Jerusalem. Meanwhile, Russia has extended emergency rules allowing it to sell lower-quality petrol to try to tackle fuel shortages triggered by Ukrainian, attacks on its oil infrastructure. The shortages are having a significant impact on daily life in
Starting point is 00:08:49 Russia, with limits on how much motorists can buy. One person who works in the Russian car industry sent us this voice note on condition of anonymity. It's read by one of our producers. I've just driven past four stations and there wasn't any petrol at any of them. Where there is fuel available, there are queues stretching for kilometres. One person I know said he spent 10 hours waiting in line. Some people are going out at night just to get in the queue early. The government has now lowered the requirements for petrol production. They started producing Euro3 fuel and it can contain 10 or even 15 times more sulfur than modern petrol. Older cars with older engines will probably cope with it, but newer cars are not designed for this kind of fuel. They can have
Starting point is 00:09:34 problems and engine damage. Three people I know have already had engine failures. Euro3 is simply not the raid fuel for modern cars. Nick Butler is a visiting professor at King's College London and a former BP executive. He told Anna Foster what all this means for Russia. I think what you're reporting is evidence of two things. First of all, the success of the Ukrainian drone attacks, which have attacked the key refineries, including the Moscow refinery over the last few weeks. And the Russians clearly don't have alternative capacity to supply.
Starting point is 00:10:11 the proper grades of petrol that they need. And the second thing is the extent to which energy is now, an energy supply is now a target within conflicts like this and would be a target in any future conflict. And in practical terms, this fuel is not really designed for newer cars. Cars tend to be built around the type of fuel that they use. And this isn't really what we have now. That's right.
Starting point is 00:10:36 I think what the Ukrainians have done is take out the capacity of the new, newer, the higher quality refineries in Russia, and they're now having to rely on the older refineries, which can only produce this old and dirty form of petrol. I'm not surprised at all that some of the cars are not working. I think it is a real sign of a lack of resilience in Russia, and I think it is going to be economically damaging, because as well as what you've reported, the Russians have also banned exports of diesel, which is a significant. It's a significant economic loss for them. And they're having to import oil products now, according to these reports from India and other people. So I think this is a real setback and a real victory for
Starting point is 00:11:24 the Ukrainians. Is there much that Russia can do to help itself without some type of sanctions, relief? It's hard to see. You can't build new refineries very quickly. The Moscow refinery, which was damaged, I think last week, is now said to be out of action for the rest of year. They can only rely on these old refineries. They're probably having to reopen some of them. That's the first level of resilience, but it's not sufficient when the vehicles in Russia need something better to keep running properly. Nick Butler. Japan says it recognizes the need to improve counterintelligence operations after the New York Times reported that Russia was taking advantage of its weak espionage laws. A Japanese government spokesman said greater rigor was needed to
Starting point is 00:12:11 stop foreign intelligence activities on Japanese soil. As well as information gathering, the paper says Japan is being exploited as a source of dual-use components, with 90% of Russian missiles and drones containing Japanese parts. Jane Bradley worked on the investigation. Sean Lay asked her why Japan had become so attractive to Russian spies. There are two main reasons. One is the country's weak espionage laws,
Starting point is 00:12:37 and two is its booming high-tech industry, which basically creates the technology, these dual-use parts that Russia needs to keep its missiles, its drones, flying, attacking Ukraine. Japan has been known as a spy paradise for decades ever since its intelligence capabilities were stripped back by the wars victors after World War II. And since then, kind of Japanese officials have said the laws have kind of been frozen in time. So the current Prime Minister Takeichi is currently trying to bolster Japan's intelligence capabilities. but at the same time where we have all this rhetoric about the importance of national security, about being a very vocal, very early supporter of Ukraine,
Starting point is 00:13:17 you've got this network of spies and operating under Japan's nose and Japanese manufacturers' parts repeatedly turning up on the battlefield in Ukraine. Now you talk about this 20th Directorate operating, you say, out of Aeroflot's office in Tokyo in the heart of the city of Japan, not so very far away from police headquarters. it walk away. Yeah, it's literally, I was surprised why I went to Tokyo in March to basically try and track down one of the 20th directorates offices, a guy called Maxime Fulchenkov and he heads up the Russian, the 20th operation in Japan. So we went to track down him and also the network of middlemen businesses, which are intelligence officials suspect helping him get this
Starting point is 00:14:05 technology to Russia. Because this stuff isn't necessarily going direct to Russia from Japan, because presumably Japan observes all the sanctions and so on that have been imposed, but it's going to other countries. Yeah, that's the thinking. So Japan, very early on, I think the first day that Russia invaded Ukraine actually announced sanctions against Russia and it actually played a big role in developing this list of dualies technology, which are under great export restrictions. So it's completely illegal against export rules to direct. exported from. So where does it go to? A bunch of middlemen and the biggest country which received Japan's export is Vietnam. Vietnam has no sanctions against Russia and it is also, as it happens,
Starting point is 00:14:49 the biggest importer of technology to Russia. So the technology does not need to go, as you say, directly from Japan to Russia. It can go through these transit companies which in theory don't explicitly break laws, but these companies who are shipping them from Japan do have a responsibility to ensure the end user, the end country is not Russia. Just in the last few moments we have, I mean, some big names here, Nippon, Panasonic, Tashiba and others. What do the companies say? Yeah, so the companies all deny any wrongdoing and say they very strictly follow all Japan's export rules and sanctions. Nippon itself said that the technology is old and it has not been made by the company for the years.
Starting point is 00:15:29 But there are questions that remain because 90% of components Ukraine says that it's finding in the battlefield are made by Japanese manufacturers. Jane Bradley of the New York Times. Still to come on the podcast. I never imagined that I would find a career as an actor. I think I have been extremely blessed because it wasn't something I sought. It just happened by degrees and surprise followed surprise. Tributes are coming in to the Jurassic Park star Sam Neal,
Starting point is 00:15:58 who's died at the age of 78. I'm Keanu and I leveled up my business with Shire. Once I figured out that Shopify was a thing, I never turned back. I can create a site with my eyes closed. Shopify thinks ahead of us, you know, and it thinks about the customer more than anything. Every day I'm thinking about some other new business. But Shopify is doing it to me because it's so easy to use. It's like I can't stop. I'm addicted.
Starting point is 00:16:34 Start your free trial at Shopify.com. Don't play games with us. A vicious gang of hackers. chaos for businesses, councils and hospitals. What if I don't finish this treatment and his cancer grows? But they didn't care. I'm dying laughing. Making outrageous demands for money.
Starting point is 00:16:54 They wanted millions. It was high tech and high stakes. The country's under attack. And it was highly secretive until someone exposed it all. Cyberhack, season four, The Conti Files. Listen on BBC.com or wherever you get your BBC podcasts. This is the Global News Podcast. The Spanish Prime Minister Pedro Sanchez is visiting a wildfire hit region in the southern province of Almaria.
Starting point is 00:17:24 At least 13 people have died and an area of around 7,000 hectares, 70 square kilometres, has been burnt. Mr. Sanchez has been speaking to the media. We're very saddened about all these neighbours that have died. And I want to say that we've been offered the solidarity of many years. European governments who also are suffering the consequences of climate change in the form of wildfires or other events. And I think that the cooperation with Europe is also going to be needed in the next few months. Officials say the blaze has now been stabilized, allowing hundreds of evacuees to return home. I got an update from our Madrid correspondent Guy Hedgeco.
Starting point is 00:18:12 The improvement has continued. The conditions are still relatively good in terms of the temperature being lower than it had been in the previous days. There's more humidity, less wind. That means the local government has been able to say that the fire has been stabilized. The regional president of the Andalusia region where Al-Maria is, Juan Marino has said that this was the beginning of the end of what had been a terrifying fire, as he put it. So there does seem to be optimism there. 1400 people who had been evacuated from their homes are slowly being able to return back to their homes. But of course, yeah, we do have that death toll of 13 people now.
Starting point is 00:18:54 The hope is that the number of dead will not increase any further. How are things looking for the rest of the summer in terms of more fires? Already it's been a bad summer in terms of fires, in terms of the amount of land that has been burned. It's been well above average. There have been a number of fires burning up in the north. in Catalonia, some other areas as well, even before this latest fire. So there is concern that if it does turn out to be a very dry, hot summer, which it looks like being, then it's going to be a very difficult summer in terms of wildfires here in Spain. Guy Hedgeko in Madrid. Nearly three
Starting point is 00:19:31 million people in China have had to be evacuated from their homes as a result of Typhoon Bavi. The most powerful storm to hit mainland China this year, it brought heavy rain and violent winds to the East Coast as it made landfall on Sunday. Hundreds of flights and train services were cancelled. Stephen MacDonald in Beijing has the details. The impacts of this typhoon are still being felt right along the length of China, especially on the East Coast. And there's footage coming through showing heavy driving rain,
Starting point is 00:20:03 very strong winds and naturally also flooding. Emergency teams have been reaching various cut-off towns to rescue people, and then as the floodwaters have receded, the big job of clearing roads using chainsaws and heavy digging equipment to try and clear a path, certainly for people to be able to get on with their normal lives, but also to allow the emergency teams to reach other cutoff parts of the country. Hundreds of flights and train services have been cancelled and so quite a significant disruption to the economy here. But that said, the Chinese government is, pretty good at handling these typhoon, these summer typhoon situations, and we've not seen,
Starting point is 00:20:47 for example, a huge loss of life. However, over the coming days, the sort of fallout from this typhoon has been that this weather system remains, and there could still be heavy rain over the coming days. Now, of course, the longer term scenario is that every summer now, these serious, dangerous weather situations in China are getting worse and worse. and scientists to blaming this on climate change, and it's one of the reasons why it's really focused the attention of the Chinese government to try to do something about it. This is a country, of course, which still building coal-fired power stations,
Starting point is 00:21:26 but also throwing a lot of effort into renewable energy to try and fix this problem in the long run because this is becoming a serious thing every summer here that the authorities have to deal with these heavy, serious weather emergencies. Finally, the actor Sam Neal has died at the age of 78. He starred in a huge range of Hollywood films, including the piano and the hunt for Red October. But he's probably best known for his role in Jurassic Park. Here he is as Dr. Alan Grant describing the deadly velociraptor.
Starting point is 00:22:00 You stare at him, and he just stares right back. And that's when the attack comes, not from the front, but from the side. From the other two raptors, you didn't even know we're there. Sam Neal spoke to the BBC a few years ago, following the release of his autobiography, Did I Ever Tell You This? You know how they tell children you should always follow your dreams? I came from a small town in, well, I was born in Northern Ireland initially
Starting point is 00:22:30 and then a small town in New Zealand. Well, I didn't have dreams particularly. I never imagined that I would find a country. career as an actor, little than an actor on screen. So once I started getting work, it was a great surprise to me. And I continued to be surprised to this day when my agent calls up and says someone, someone wants you to do a series. Yeah, I think I have been extremely blessed because it wasn't something I sought.
Starting point is 00:23:01 It just sort of happened by degrees and surprise followed surprise. I feel really at home on sets. It doesn't matter where in the world you are. And I really like being in the company of other actors. I think actors are the best company in the world. So I couldn't think of a better job, really. Sam Niel himself. Well, away from the big screen,
Starting point is 00:23:22 he also developed an interest in making wine at his vineyard on New Zealand's South Island. Film critic Kate Roger said many Kiwis had embraced the late actor as one of their own, and his death had hit the nation heart. Honestly, it's been shock. It's been like we've kind of lost a member of the family. He had that kind of feel about him all across TV and movies, obviously,
Starting point is 00:23:44 but his interviews and also his phenomenal presence on Instagram when he's going live from his farm with his pig named after Helena Bonham Carter. He has so accessible. He has such an irrepressible joy and innate Kiwi bloke kindness to him that even if people didn't know him, or Kiwis he'd never met him, They've been saying, you know, they feel like they've lost someone that they've known their whole lives. We heard more about Sam Neal's death from our entertainment correspondent, Colin Patterson. Really sad story this one.
Starting point is 00:24:16 It was only a few months ago that his family announced he was cancer-free. And in fact, it was three years ago that he revealed in a very public way that he'd been diagnosed with angioimmune moplastic T-cell lymphona. But this family have been keen to stress this morning that he died cancer-free. so we don't know what he died off, but it wasn't the cancer that had made such headlines three years ago. But I'd like to focus on the acting, and in particular, one year in his career, which basically sums up the way that he had the charisma and the charm and the versatility to do both blockbusters and art house films. 1993, he was in the film that was the biggest box office hit in the world.
Starting point is 00:24:59 Stephen Spielberg's Jurassic Park, he played the paleontologist, Dr. Alan Grant. Yes, it was a technological marvel, but he provided real heart at the center of it. So the biggest film in the world, and also he was in The Piano, Jane Campion's Palm Door winner. It couldn't have been a more different film.
Starting point is 00:25:19 In it, he played a frontiersman. Well, it was a period piece, and he was married to a mute woman played by Holly Hunter who played the piano. When she had an affair on him, he got so angry, he chopped off one of her fingers. So we have Blockbuster, we have Art Towers. in the same year, which really is quite an achievement to win the palm door and of the biggest
Starting point is 00:25:38 hit in the world. Yeah, the biggest hit. But he also appeared on the small screen, starring in series, but also popping up here and there in other programmes. Yeah, in particular, the one that a lot of listeners will have seen him in in the last decade. Piki Blinders, he was in the first two series of that, playing a corrupt police officer from Northern Ireland. And interestingly, he was born in Northern Ireland, because although his father was a New Zealander, He was there on army duty, and it was only eight years old when he moved to New Zealand, although it was Australia, which really became his home and where he started his professional career. And it's a sign of just how revered he is that the Prime Minister of Australia, Anthony Albanese, has paid tribute to him today, saying Sam Neal starred in so many beloved Australian stories, and he earned a special place in Australian hearts. Ryan Dry, thoughtful and laconic, Sam fought illness with the same dignity, humour and conviction that he gave strength to his every performance.
Starting point is 00:26:39 Colin Paterson on Sam Neal, who's died at the age of 78. And that is all from us for now, but the Global News podcast will be back very soon. This edition was mixed by Nicola Brough and produced by Adrian White. Our editor is Karen Martin. I'm Oliver Conway. Until next time, goodbye. us. A vicious gang of hackers, causing chaos for businesses, councils and hospitals. What if I don't finish this treatment and his cancer grows? But they didn't care.
Starting point is 00:27:16 I'm dying laughing. Making outrageous demands for money. They wanted millions. It was high tech and high stakes. The country's under attack. And it was highly secretive until someone exposed it all. Cyberhack, season four, The Conti Files. Listen on BBC.com or wherever you.
Starting point is 00:27:35 get your BBC podcasts.

There aren't comments yet for this episode. Click on any sentence in the transcript to leave a comment.