Huberman Lab - AMA #5: Intrusive Thoughts, CGMs, Behavioral Change, Naps & NSDR

Episode Date: March 24, 2023

Welcome to a preview of the fifth Ask Me Anything (AMA) episode, part of the Huberman Lab Premium subscription. The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation. Subscribe to Huberman Lab Premium at https://hubermanlab.com/premium Timestamps (00:00:00) Introduction (00:01:53) Strategies for Abstaining From Addictive Thoughts and Narratives (00:21:07) Huberman Lab Premium In the full AMA episode, we discuss: Continuous Glucose Monitors (CGMs) How to Build Good Habits Alongside a Partner Who Challenges Them? Short Naps vs. Non-Sleep Deep Rest (NSDR) for Replenishing Energy and Dopamine Title Card Photo Credit: Mike Blabac Disclaimer

Welcome to the Huberman Lab podcast where we discuss science and science-based tools for everyday life. I'm Andrew Huberman and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine. Today is an Ask Me Anything episode or AMA. This is part of our Premium Subscriber Channel. Our Premium Subscriber channel was started in order to provide support for the standard Huberman Lab podcast, which comes out every Monday and is available at zero cost to everybody on all standard feeds, YouTube, Apple, Spotify and elsewhere. We also started the premium channel as a way to generate support for exciting research being done at Stanford and elsewhere, research on human beings that leads to important discoveries that assist mental health, physical

health, and performance. I'm also pleased to inform you that for every dollar the Huberman Lab Premium channel generates for research studies, the Tiny Foundation has agreed to match that amount. So now we are able to double the total amount of funding given to studies of mental health, physical health, and human performance. If you'd like to subscribe to the Huberman Lab Podcast Premium Channel, please go to HubermanLab.com slash premium. It is $10 a month to subscribe, or you can pay $100 all at once to get an entire 12-month

subscription for a year. We also have a lifetime subscription model that is a one-time payment, and again, you can find that option at HubermanLab.com slash premium. For those of you that are already subscribers to the premium channel, please go to HubermanLab.com slash premium and download the premium subscription feed. And for those of you that are not Huberman Lab podcast premium subscribers, you can still hear the first 20 minutes of today's episode and determine whether or not becoming a premium subscriber is for you. And now without further ado, I will answer your questions.

And as always, I will strive to be as thorough as possible, as clear as possible, and as concise as possible. Our first question is about abstaining from thoughts. And in answering this question, we're gonna skirt right up against a topic that I've covered before on the podcast, which is obsessive compulsive disorder, which is a very serious disorder.

I mean, it can have a range of severity, but people with true OCD suffer a lot from obsessions. These are intrusive thoughts and compulsions, which are the behaviors typically associated with those thoughts. I think it's really important that we define OCD really clearly, so that we can make sure that we're talking about intrusive thoughts and the desire to abstain from thoughts versus OCD and where there might be some overlap there. The functional definition of OCD that really pertains to the disorder, obsessive compulsive disorder, OCD as opposed to, you know, we call people neurotic or we say, you have OCD or I'm so OCD about this or OCD about that,

that's become kind of a common use of the acronym OCD. But true OCD is a situation in which the engaging in a particular compulsive behavior does not serve to reduce the intensity or the frequency of the obsessions. In fact, it makes it worse. Okay, so the typical thing that we hear these days is, oh, you're so OCD or he's so OCD or she's so OCD or I'm so OCD.

Now, if someone is OCD in that sense, okay, so not the clinical disorder, but OCD in the sense that they're really clean. They're really fastidious. They need everything perfect. However, that person can achieve some level of calm and comfort that's fairly long lasting if everything's clean and perfect.

Well, then that's not obsessive compulsive disorder. This is really important to understand as we venture into answering the question about intrusive thoughts and the desire to abstain from certain thoughts. A person with true OCD will keep cleaning and cleaning or washing their hands or arranging things at perfect right angles, but the more they do it,

the more their anxiety goes up. A person who has more typical, gosh, we don't really even have a language for this nowadays, unfortunately, but the sort of person that's extremely particular, they need things a certain way, and they're very driven to resolve things and do things to make sure that things are done

in a certain way or handled in a certain way. Well, if that person can experience relief from engaging in, let's say, exercise or from cleaning, right? You'd say, you're so OCD about exercise. Well, but if exercising for an hour or even two hours in the morning make somebody really calm in the rest of the day and they don't need to exercise, well then they're not necessarily true OCD. They don't necessarily have a disorder related to exercise. However, if they're exercising for two hours in the morning and then they find they can't

concentrate on other things and their desire to exercise just increases and increases and becomes intrusive for them disrupting their quality of life throughout the day. Well then that's falling in there the umbrella of what we would call a true disorder. Okay, so we want to highlight that because the question is about a desire to abstain from thoughts and the question is in your discussion with Dr. Ana Lemke. And I should just mention Dr. Anna Lemke is the director of our dual diagnosis, addiction clinic at Stanford University School of Medicine. She's the author of this incredible book, Dopamine Nation, that I think everybody should read. I do believe everyone should read that book.

So important for the addict and non-addict alike, because it deals with basically the state of our life nowadays. We're living in this dopamine rich world where we can quickly become dopamine depleted, which is terrible, leads to depression, in addition to things like addiction and some folks, et cetera. Ana was a guest on the podcast. You can find her episode at hubraminlab.com. Just put Ana, I think she's the only guest

we've had thus far whose name is Ana, so it'll just pop up there. The entire website is searchable, but if you want to listen to that episode or watch that episode, you can access it at hubraminlab.com. The question is, in your discussion with Dr. Anulemki, you were talking about abstaining from people's drug of choice for 30 days to reset the dopamine reward path. And indeed, that is the prescriptive that Dr. Anulemki gives for most all addictions and for people that are suffering from milder, even severe depression related to dopamine seeking behaviors, social media, video games, sex, food, etc. However,

of course, in the instance of food or in some other addictions, you can't abstain for 30 days. That would be terrible to abstain for food for 30 days. I'm sure people have done it, but it is not healthy to do. Certain things like alcohol and drugs, people can abstain for 30 days in an effort to never go back to them again. There are cases of severe alcohol or opiate dependence where people can't go cold turkey or they risk dying. So there they need to really work with a physician.

But the 30-day reset of the dopamine system is something that's very real and that pertains to most people. That is, it's going to be very effective for most people struggling with either behavioral, what are sometimes called process addictions or other types of addictions, including substance abuse issues. The question continues. You said you were going to ask on how to abstain if your drug of choice is a thought or narrative

as opposed to a substance or behavior. The question continues as far as I can tell, your discussion with Ana moved on before you asked her the question, would you be able to discuss strategies for abstaining from addictive thoughts and narratives? Okay, so let's talk about intrusive thoughts and let's start off by asking ourselves what is a thought? Okay, in the realm of neurobiology, we have sensations which are the processes by which our neurons and nerve cells convert light photons, sound waves, touch, mechanical pressure, etc. into

electrical signals and chemical signals that head into our nervous system, including our brain, and then our brain, at least we think, make sense of them and help us navigate the world that we're in. So the sensation part is a pure transformation of mechanical information, or in some cases, chemical information, like smell, chemicals, literally, volatile chemicals floating around in the world,

they're brought into your nose and neurons in your olfactory bulb convert those into electrical and chemical signals that your brain can understand. Perceptions are your idea of what those signals out in the world are, either because you're paying attention to them or for some other reason, you decide that stop sign in front of you is red and that the sign behind it is white and that the sky is blue or cloudy, those are perceptions. Okay, so we have sensations and perceptions. Then we have emotions, which are these things that include the mind and body that are related to neuromodulators like dopamine, serotonin, etc.

Although those chemicals do other things as well. And then of course we have behaviors, actions, everything from me moving my pen on a piece of paper to walking, running, et cetera. Thoughts are a fifth category of neural functioning that we really need to define, but that doesn't have as strict a definition as sensations, perceptions, or feeling, or action. But thoughts are real, right? We all know this. Thoughts are real. And one way that we can define thoughts is that thoughts are perceptions that include data from the past, present, or future, okay? Or combinations of past and present, or present and future, or future and past, okay?

I'm not trying to give an overly complicated definition here, but if we are going to answer a question about how to abstain from thoughts in a really direct and actionable way, we really need to address what are thoughts. So thoughts are perceptions that are generated internally, right? We don't need any external sensation in order to have a thought. We can close our eyes. We could be in sensory isolation for that matter. We can be floating with no gravity, and we can have a thought. Thoughts tend to run pretty much automatically in the background

all the time. Some people refer to this as chatter in the back of our minds in a very unstructured way. And then if we force our thoughts to be structured because we decide they need to be, or if something in our environment captures our perception, then our thoughts tend to be structured. Let me give you an example. If I'm just walking around, if there were a way in which we could broadcast my thoughts onto a screen.

I hope we wouldn't do that. But those thoughts would be a mixture of semi-complete sentences and gibberish. However, if somebody stops me and says, hi, good to see you. What are you doing today? And I started answering, well, then my thoughts are suddenly being driven by an external stimulus, their question, and some internal ideas, memory of who I am and what I'm doing that day, so past and present, and so on, and so thoughts become structured. So when we have a question about how to abstain from thoughts, we need to be additionally specific, and really pinpoint that what we're trying to do is to abstain from thoughts we don't want, presumably, either because they

are too repetitive and distracting or because what's contained in those thoughts is disturbing. Okay. This is important because it gives us two answers to the questions that are highly divergent. One answer to the question of how to abstain from intrusive thoughts, you know, thoughts that we're addicted to, is if those thoughts are merely on loop all the time and we can't stop them, but the thoughts themselves aren't particularly disturbing. So think about a song you can't get out of your head or you keep recounting some event, but the event itself isn't very disturbing. It's just intrusive because it's there. Well, in that case, the data really point to trying to anchor your thoughts to some external stimulus. So getting into action,

getting into activities that really draw your attention away from that thought. Now, you may still hear it scrolling in the background. So you might be sitting in class, still hearing that loop of thoughts in the background. That's something that over time ought to wane, it ought to disappear. in the background, that's something that over time ought to wane, it ought to disappear. If we try and bring more and more attention to whatever it is that's in our environment, whatever it is that we happen to be learning or doing physically, et cetera. Things like mindful meditation, doing a 10 or even just five minute to day practice of sitting with eyes closed or lying down with eyes closed and really focusing on one's breath, focusing one's attention on the, sometimes it's called the third eye center, but in science we'd say just the region right behind the forehead, you're directing your attention there has been shown to increase focus for singular topics and can improve memory into a bunch of other things as well. Those are data from Dr. Wendy Suzuki's lab at New York University. She was a guest on the podcast as well.

My laboratory has run studies on mindful meditation as well. So what you're really trying to do is learn how to focus better on one thing and by focusing on that one thing, you focus off these repetitive thoughts. Now, I have a feeling that this question was asked and that many people upvoted this question because the issue is in just thoughts that are intrusive because they're there and on repeat, but because the thoughts themselves are actually troubling.

This could be recounting a trauma, someone harmed you, you observed something that was disturbing, you felt wronged, you felt someone else was wronged, you can't seem to get your mind off of something and your emotions tend to follow. And so it's uncomfortable. I have a feeling this is the root of the question. In that case, the approach is very different. What we know from essentially all of the quality scientific and clinical studies is that those sorts of intrusive thoughts are very much like a trauma. Now we have to be

clear in defining what trauma is. I'll use the definition, the Dr. Paul Conti, another incredible guest that was on our podcast, psychiatrist, Stanford Harvard trained psychiatrist. I think one of the world's foremost leaders on the issue of trauma and psychiatry and psychology generally. He defines trauma as an event or something that fundamentally changes the way that your nervous system works such that you function less adaptively going forward from that event. Okay, so not every bad occurrence in your life is a trauma. That's good news.

The bad news is many people have traumas and traumas change the way that our nervous system works so that we don't function as well as we could. So in that sense, intrusive thoughts that are disturbing are in many ways traumas and are reinforcing that trauma. Now, we know that almost counterintuitively, in order to deal with trauma, you have to get very close to that trauma. You don't have to re-expose, and I would hope you would not re-expose yourself to the very same trauma. But we know that one of the best ways to deal with traumas is to get very clear about the narrative around those traumas.

Now, this can be done with a therapist, ideally, but not everyone has access to therapy or can afford therapy. There's a range of quality of therapists for that matter. So we're always referring to the desire for people to do great therapy with really great, meaning excellently trained people. But it turns out that if you want to extinguish an intrusive thought, one of the best ways to do that is to journal about that particular thought extensively. So rather than the earlier strategy for intrusive thoughts where they're

just on loop and intrusive because they're on loop and present, but their content isn't disturbing. When a thought is disturbing and intrusive, we know that it's very useful to script out as much detail about that particular thought and the things around it as possible. Obviously, you want to do this in a way that is fairly structured, so you ideally would use complete sentences. So the reason for doing that is that thoughts, as I mentioned earlier, can often be fragmentary. So they pop up in our mind almost seemingly spontaneously.

They're inhibiting our ability to focus or be present to work or family or other things or sleep. Writing things down in a lot of detail does seem to have this quality of both reducing the emotional load of whatever it is that that thought is about, as well as diminishing the frequency of those intrusive thoughts over time. So this is far and away different than the strategy I mentioned for the other types of intrusive thoughts, and really it's far and away different from the 30-day abstinence approach that Dr. Analemki was talking about for substance or behavioral addictions. Now, of course, this process of abstaining from thoughts or removing the addictive nature of certain thoughts

can definitely take some time. So a good example there would be superstitions. You know, I'll come clean here and I've talked about this before on a few podcasts that when I was in college, I developed a sort of knock on wood superstition. Any time I'd say something that I didn't want to happen or did want to happen. I'd say knock on wood and I'd knock on wood superstition. Anytime I'd say something that I didn't want to happen or did want to happen, I'd say knock on wood and I'd knock on wood. And then I started suppressing the behavior, most of the reason it was a little embarrassing. And then I started just telling myself in my head, knock on wood, knock on wood, knock on wood.

And it was clearly a little bit of an OCD type thing. But again, OCD in air quotes here. I think it qualified as OCD in the sense that the more I did it, the more I wanted to do it. So I needed to go cold turkey on the thinking, but how can you go cold turkey on a thought? You couldn't. What I was told to do and what worked very well for me was to just write down the worst possible outcome that I was concerned about. So to really get close to the nature or the underlying basis of that intrusive thought.

And I raised this because a lot of times the intrusive thought is not, okay, I'm thinking about a car accident or I'm thinking about a breakup or I'm thinking about an exam that I have. That can be intrusive, but a lot of times it's some kind of nebulous abstract set of words or ideas or images around something that happened

that we saw or heard or experienced. And by putting a lot of clear structure to what the thought is exactly and to putting some thought and structure onto paper about what that pattern of not healthy thinking relates to, people often achieve tremendous relief in a fairly short amount of time. Sometimes just in one section of writing it down, sometimes they need to write it down multiple times.

What you're essentially trying to do with an intrusive thought or a trauma of any kind is you're trying to turn a disturbing story. That is a story that evokes a lot of emotion and captures that kind of hijacks your nervous system Stirring story that is a story that evokes a lot of emotion and Captures it kind of hijacks your nervous system into what is essentially a known but repetitive and kind of old boring story Where the emotional load has been depleted and there of course I have to highlight the fact that getting sufficient Rapid eye movement sleep We also know is very important for removing the emotional load of traumatic experiences and

intrusive thoughts. So you really want to strive to get the best possible sleep you can that includes sufficient rapid eye movement sleep. And we have multiple zero cost resources for that at HubermanLab.com. We have the episode on Mastery or Sleep. We have the episode on Perfect Your Sleep. We have the Toolkit for Sleep, all of are timestamped, and all of which can be accessed to completely zero cost to try and get your sleep as good as possible, including lots of rapid eye movement sleep.

So in order to remove intrusive and addictive thoughts, ask yourself, is this OCD of the classic sense? If it is, you should see a psychiatrist. They won't necessarily prescribe medication, but there are tools for true OCD that are very effective in many cases. And we did the episode on OCD, which I invite you to listen to as well. You want to ask yourself, are the thoughts disturbing or merely intrusive and repetitive? If they're merely intrusive and repetitive, well then learning to focus your attention on other things and getting better at focusing on single things through an exercise like mindfulness meditation can really help.

And indeed, perhaps the best use of mindfulness meditation is to improve your level of focus. It does have other benefits as well, but that's going to be the major one that one will experience, even with these very short five or ten-minute day meditations. Great data on that from the scientific literature. And then, if those intrusive thoughts are not only intrusive, but they're also disturbing, in that case, you really want to put as much structure and thought, believe it or not, into what those thoughts are really about. Write them out on paper in complete sentences, and maybe do that multiple times

until the underlying emotions related to those thoughts really start to diminish. And by doing that, you're essentially doing your own form of trauma therapy for lack of a better way to put it. And again, the data really point to the fact that getting close to the specific details around those intrusive thoughts is going to be the

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