Huberman Lab - Dr. Andy Galpin: How to Build Strength, Muscle Size & Endurance

Episode Date: March 28, 2022

My guest is Dr. Andy Galpin, Professor of Kinesiology at California State University, Fullerton, and one of the foremost experts in the world on the science and application of methods to increase stre...ngth, hypertrophy and endurance performance. We discuss fundamental principles of strength and hypertrophy training and building endurance, the mechanisms underlying them and we review specific protocols to optimize training and recovery. We also discuss hydration, sleep, nutrition, supplements, and mental tools that can be leveraged to accelerate adaptations leading to enhanced strength, muscle growth and/or endurance. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Dr. Andy Galpin, Strength & Endurance Training   (00:03:23) Sponsors: AG1, LMNT (00:08:20) Adaptations of Exercise, Progressive Overload  (00:14:40) Modifiable Variables, One-Rep Max, Muscle Soreness (00:27:30) Modifiable Variables of Strength Training, Supersets   (00:43:50) How to Select Training Frequency: Strength vs. Hypertrophy  (00:58:45) Hypertrophy Training, Repetition Ranges, Blood Flow Restriction  (01:08:50) Tools: Protocols for Strength Training, the 3 by 5 Concept  (01:10:48) Mind-Muscle Connection  (01:16:16) Mental Awareness  (01:27:57) Breathing Tools for Resistance Training & Post-Training  (01:37:25) Endurance Training & Combining with Strength (01:51:20) Tools: Protocols for Endurance Training (02:08:15) Muscular Endurance, Fast vs. Slow Twitch Muscle  (02:16:35) Hydration & the Galpin Equation, Sodium, Fasting    (02:35:57) Cold Exposure & Training   (02:43:15) Heat Exposure & Training  (02:53:47) Recovery   (03:04:02) Tool: Sodium Bicarbonate (03:17:26) Tool: Creatine Monohydrate (03:20:08) Absolute Rest (03:29:08) Zero-Cost Support, YouTube Feedback, Spotify, Apple Reviews, Sponsors, Supplements, Instagram, Twitter Title Card Photo Credit: Mike Blabac Disclaimer

Transcript
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Starting point is 00:00:00 Welcome to the Huberman Lab Podcast where we discuss science and science-based tools for everyday life. I'm Andrew Huberman and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine. Today my guest is Dr. Andy Galpin. Dr. Galpin is a full and tenured professor in the Department of Kinesiology at California State University in Fullerton. He is also a world expert in all things exercise science and kinesiology. Today you are going to hear what is essentially a master class in how to build fitness, no matter what level of fitness you happen to have. He talks about how to build endurance and the multiple types of endurance. He talks about how to build strength and hypertrophy, which is the growth of muscle fibers.
Starting point is 00:00:46 So if you're seeking to get stronger or build bigger muscles or build endurance or all of those things, today you're going to learn how. You're also going to learn how to build flexibility, how to hydrate properly for exercise, and we'll also talk about nutrition and supplementation. What makes Dr. Galpin so unique is his ability
Starting point is 00:01:04 to span all levels of exercise science. He has the ability to clearly communicate the sets and repetition schemes that one would want to follow, for instance, to build more strength or to build larger muscles. He also clearly describes exactly how to train if you want to build more endurance or enhance cardiovascular function. What's highly unique about Dr. Galpin and the information he teaches and the way he communicates that information is that he can take specific recommendations of how recreational exercises or even professional athletes ought to train for their specific goals and the link that to specific mechanisms, that is the specific changes that need to occur in the nervous system
Starting point is 00:01:44 and in muscle fibers and indeed right down to the genetics of individual cells in your brain and body in order for those exercise adaptations to occur. It's truly rare to find somebody that can span so many different levels of analyses, and who is able to communicate all those levels of understanding in such a clear and actionable way. Indeed, Dr. Galpin is one of just a handful of people to which I and many others look when they want to make sure that the information that they're getting about exercise
Starting point is 00:02:12 is gleaned from quality peer reviewed studies, hands-on experience with a wide variety of research subjects, meaning everyday people, all the way up to professional athletes in a wide variety of sports. So it's no surprise that he's not only one of the most knowledgeable but also the most trusted voices in exercise science. Dr. Galpin is also an avid communicator of zero cost to consumer information
Starting point is 00:02:33 about exercise science. You can find him on Instagram at Dr. Andy Galpin and also on Twitter at Dr. Andy Galpin. Both places he provides terrific information about recent studies both from his laboratory and from other laboratories, more in-depth protocols of the sort that you'll hear about today. So if you're not already following him, be sure to do so. He provides only the best information. He's extremely nuanced and precise and clear in delivering that information. I'm certain that by the end of today's conversation, you'll come away with a tremendous amount
Starting point is 00:03:04 of new knowledge that you can devote to your exercise pursuits. Before we begin, I'd like to emphasize that this podcast is separate from my teaching and research roles at Stanford. It is, however, part of my desire and effort to bring zero cost to consumer information about science and science-related tools to the general public. In keeping with that theme, I'd like to thank the sponsors of today's podcast. Our first sponsor is Athletic Greens. Athletic Greens is an all-in-one vitamin mineral probiotic drink. I've been taking Athletic Greens since 2012, so I'm delighted that they're sponsoring the podcast. The reason I started taking Athletic Greens and the reason I still take Athletic Greens once or twice
Starting point is 00:03:40 today is that it helps me cover all of my basic nutritional needs. It makes up for any deficiencies that I might have. In addition, it has probiotics, which are vital for microbiome health. I've done a couple of episodes now on the so-called gut microbiome and the ways in which the microbiome interacts with your immune system, with your brain to regulate mood, and essentially with every biological system relevant to health throughout your brain and body. With athletic greens, I get the vitamins I need, the minerals I need, and the probiotics to support my microbiome. If you'd like to try athletic greens, you can go to athleticgreens.com slash Huberman and
Starting point is 00:04:15 claim a special offer. They'll give you five free travel packs plus a year supply of vitamin D3K2. There are a ton of data now showing that vitamin D3 is essential for various aspects of our brain and body health, even if we're getting a lot of sunshine, many of us are still deficient in vitamin D3. And K2 is also important because it regulates things like cardiovascular function, calcium in the body, and so on. Again, go to athleticgreens.com slash uberman to claim the special offer of the 5 free travel
Starting point is 00:04:42 packs and the year supply of vitamin D3 K2. Today's episode is also brought to us by Element. Element is an electrolyte drink that has everything you need and nothing you don't. That means the exact ratios of electrolytes are an element and those are sodium, magnesium, and potassium, but it has no sugar. I've talked many times before on this podcast about the key role of hydration and electrolytes for nerve cell function, neuron function, as well as the function of all the cells and all the tissues and organ systems of the body. If we have sodium, magnesium, and potassium present in the proper ratios, all of those cells
Starting point is 00:05:16 function properly and all our bodily systems can be optimized. If the electrolytes are not present and if hydration is low, we simply can't think as well as we would otherwise. Our mood is off, hormone systems go off, our ability to get into physical action to engage in endurance and strength, and all sorts of other things is diminished. So with element, you can make sure that you're staying on top of your hydration and that you're getting the proper ratios of electrolytes. If you'd like to try element, you can go to drink element that's LMNT.com slash Huberman, and you'll get a free element sample pack with your purchase.
Starting point is 00:05:49 They're all delicious. So again, if you want to try element, you can go to elementlmnt.com slash Huberman. And now, for my discussion with Dr. Andy Galpin. Welcome, Dr. Professor Andy Galpin. It's been a long time coming. We have friends in common, but this is actually the first time we've sat down face to face. Yeah, I'm very excited.
Starting point is 00:06:09 Yeah, there are only a handful of meaning about three or four people who I trust enough in the exercise physiology space that when they speak, I not only listen, but I modify my protocols. And you are among those three or four people. First of all, a debt of gratitude. Thank you. You've greatly shaped the protocols that I use, and I know there's far more for me and for others to learn.
Starting point is 00:06:37 Your professor, you teach in university, and you have a tremendous range of levels of exploration. Muscle biopsy, literally images down the microscope all the way to training professional athletes and everything in between. So you are truly an end of one. And just to start us off, I would love to have you share with us what you think most everybody or even everybody should know about principles of strength training, principles of endurance training, and principles of let's call it hypertrophy power and the other sort of categories of training. And this could be very top contour, but what do you think everybody on planet earth should
Starting point is 00:07:19 know about these categories of personal and athletic development? Well, that's a great first question. Holy cow, I think I'll start it this way. I tend to think about, there's about nine different adaptations you can get from exercise. Fat loss is not one of those, it is a byproduct, but that's not really what I'm getting at. And so we can kind of categorize everything like that.
Starting point is 00:07:41 And what we're gonna, we can talk about are what are the concepts that you need to hit within each one? Then you could have infinite discussion of the different methodologies. That first thing to hit is the concepts are actually fairly few, but the methods are many. People have said that in iterations throughout time. If you walk from the very beginning, the first one to think about is what we'll just call skill. This is improving anything from, say, a golf swing to a squatting technique to running.
Starting point is 00:08:09 This is simply moving mechanically how you want your body to move. I'm just going to globally call that skill. From there, we're going to get into speed. This is moving as fast as possible. The next one is power. And power is a function of speed, but it also a function of the next one, which is strength. So if you actually multiply strength by speed, you get power. And the reason I'm making this distinction, by the way, is some of these are very close
Starting point is 00:08:33 and I'm going in a specific order on purpose here. For example, power is, like I just said, it's a function of speed and strength. So if you improve speed, you've also likely improved power, but not necessarily, because it could have come from the forest direction either. So there's carryover, so like the lot of things that you would do for development of strength and power, they are somewhat similar, but there's differences, right? So things that you would do correctly for power would really not develop much strength and vice versa.
Starting point is 00:09:01 So we can get into all these details later. Once you get past strength, and the next one kind of down the list is hypertrophy. This is muscle size, right? Growing muscle masses is the one way to think about it. After hypertrophy, you get into these categories of the next one is, these are all globally endurance-based issues, and the very first one is called muscular endurance.
Starting point is 00:09:20 So this is your ability to do, how many push-ups can you do in one minute, things like that. Past muscular endurance, you're now into more of an energetic or even cardiovascular fatigue. So you've left the local muscle and you're now into the entire physiological system and it's ability to produce and sustain work. And we can get it to a bunch of different variations with endurance, but just to keep it
Starting point is 00:09:44 really simple right now. The very first one, think about this as I call this anaerobic power, right? So this is your ability to produce a lot of work for say 30 seconds to maybe one minute, kind of two minutes like that. The next one down then is more closely lined what we'll call your VO2 max. So this is your ability to kind of do the same thing, but more of a time domain of say three to 12 minutes. So this is going to be a maximum heart rate, but it's going to be well past just max heart rate. Then after that, we have what like a long duration endurance. So this is your ability to sustain work. The time domain doesn't matter in terms of how fast you're going. It's how long can you sustain work? This is 30 plus minutes of no break like that.
Starting point is 00:10:28 So as just a high level overview, those are the different things you can target. And again, some of those crossover and some are actually a little bit contrary to the other ones. So pushing towards one is maybe going to sacrifice something else. So as an overall start, that's really what we're looking at. Within all of those, though, they do have similar concepts. In terms of there is a handful of things you have got to do to make all of those things work.
Starting point is 00:10:55 And we could talk about as many of those as you want, but one of them is functionally called progressive overload. So whichever one you're trying to improve at, if you want to continue to improve, you have to have some method of overload. And as you well know, you've talked about a lot, adaptation physiologically happens as a byproduct of stress. So you have to push your system. So if you continue to do the same exact same workout over time, you better not expect much improvement.
Starting point is 00:11:21 You can keep maintenance, but you're not going to be adding additional stress. So in general, you have to have some sort of progressive overload. And we can talk in detail about what that means for each category. But this could come from adding more weights. This could come from adding more repetitions. It could come from doing it more often in the week. It could come from adding complexity to the movement. So going from say a partial range of motion to a full range of motion or adding other variables. So there's a lot of different ways to progress,
Starting point is 00:11:48 but you have to have some sort of movement forward. So if you have this kind of routine when you've built Monday, Wednesday, and Saturday, or something, and you just do that infinitely, you're not going to get very far. So that's, I guess, the most high level overview of all the things people can go after. And then we can go from whatever direction you want from there.
Starting point is 00:12:07 I'd love to do the deep dive on each one of these for several hours. But, and I imagine that over time we probably will. I'd love to chat about a couple of these in a bit more depth. So in terms of defining what the progressive overload variables are for these different categories, maybe we could hit the two most common combinations of these nine things. The first one being strength and hypertrophy, and maybe we could lump power in there, maybe not. You're the exercise physics. but strength and hypertrophy, which at least bear some relationship. Yeah.
Starting point is 00:12:45 And then maybe separately, we could explore sustained work endurance, this 30 minutes or longer continuously, because I think many people train in that regime. Yeah. And probably something like VO2 max anaerobic as well, because I know that a number of people now incorporate so-called hit or high-intensity
Starting point is 00:13:05 interval training. I think with the hopes of either shortening their workouts and or gaining some additional cardiovascular benefit. So if we could start with strength and hypertrophy, I know many people want to be stronger, they want to grow larger muscles or at least maintain what they have. So what are the progressive overload principles that are most effective over time for strength and hypertrophy? Yeah, okay, so I'll actually go a little step back with every one of those categories I talked about. You have what we call your modifiable variables.
Starting point is 00:13:38 So this is a very short list of all the things you can modify that different variables within your work out that can be modified that will change the outcome. A fancy way of saying, if you do this differently, then you're going to get a different result. So, modifiable variables. The very first one of those is called choice.
Starting point is 00:13:55 This is the exercise choice that you select. Now, one of, I'm going to go double back here, so I'm doing a little bit of inception. So, follow me here as I'm going up a layer to come down a couple layers. I have these fundamental laws of strength in the conditioning that I'll kind of like a little bit of a joke, but progressive over those one of those laws. Another one of those laws is your exercises themselves do not determine adaptations. So here's what I mean.
Starting point is 00:14:21 If you're like, I want to get stronger, you can't select an exercise. That doesn't determine you getting strong. If you don't do the exercise correctly, and I'm not even referring to the technique, that of course matters. But if you don't execute it in the right fashion, then you're not going to get that adaptation. So if you choose, I want to get stronger. I'm going to do a bench press. Well, if you do the wrong set range, the wrong repetition range, the wrong speed, you
Starting point is 00:14:43 won't get strength, you maybe get muscle endurance, and very little strength adaptation. The exercise selection itself is important, but it does not determine the outcome adaptation. The very first thing that you need to think about if you're like, I want to get stronger or add muscle, is not the exercise choice. It is the application of the exercise. What are the sets, what are the reps, what are the rest ranges that you're using? That's going to be your primary determinant. Now some exercises are certainly better for some adaptations.
Starting point is 00:15:10 For example, a deadlift is probably not a great exercise to do for long duration endurance. You could theoretically do 30 straight minutes of deadlifting, but it's probably not our best choice. It's probably a pretty good choice for strength development, because you're going to do a low repetition high set range. You could theoretically do bicep curls for power, but probably not your best choice. So a single joint isolation movement is not the best for developing power. You've ever done a bicep curls fast as you possibly can. Like that's not going to go.
Starting point is 00:15:39 Well, so in theory, any exercise can produce any adaptation given the execution is performed properly. So now that we've understood that a little bit, any exercise can produce any adaptation, given the execution is performed properly. So now that we've understood that a little bit, the exercise itself does not determine the adaptation. Coming within each one of these categories, exercise choice is an important variable, because it does lend you two things like what movement pattern you're in. So in other words, if you want to get stronger and you're thinking, okay, what exercise do I do? You need to think a little bit about what muscle groups do I want to use, and that's going to be leading you towards the exercise choice. For example, I want to
Starting point is 00:16:15 use my quads more. Okay, fine. Maybe you're going to choose more of a front squat type of variation of goblet squat. So the bar, the load is in front of you. If you want to emphasize maybe more of your hamstrings and glutes, you're going to maybe put a barbell on your back or do a different one. So the exercise choice is important to the prescription because it's going to determine a lot of your success. Okay, another kind of simpler way to think about this. or moderate to intermediate, or maybe you don't have a coach, you probably want to hedge towards an exercise selection that is a little bit easier technically. So you maybe don't want to do a barbell back squat. It's actually a pretty complicated movement.
Starting point is 00:16:53 Maybe you want to do a little bit more of, again, a goblet squat, or even use some machines, or a split squat, something that's a little bit simpler because you don't have a coach, you're not a professional athlete. The likelihood of success is higher and the risk is now gone lower. So the very first variable within all of these is the exercise choice.
Starting point is 00:17:11 The second one is the intensity. And that refers to in this context, not perceived effort. Like wow, that was a really intense workout. It is quite literally either a percentage of your one rep at max or a percentage of your maximum heart rate or view to max. So for the strength-based things, you wanna think about what's percentage of your maximum heart rate or view to max. So for the strength based things, you want to think about what's
Starting point is 00:17:27 percentage of the maximum weight I could lift one time. And that's that's what we're going to call one rep max. Or it's a percentage of my heart rate, right? So if I tell you to get on a bike and I want you to do intervals and I want you at 75%. I'm typically referring to 75% of your max heart rate or view to max or you know, something like that. If I tell you to do squats at 75%, that means 75% of the maximum amount of weight you could lift one time or close. In terms of determining one rep max,
Starting point is 00:17:52 I confess I've never actually taken the one rep max for any exercise, but I have some internal sense of what that might be or what range it might be. Is it necessary for people to assess their one repetition maximum before going into these sorts of programs? No, not at all. I think a more intuitive way is to take a repetition range. Well, you could do this a couple different ways. So there are equations you can run and you could just google these anywhere and these are called conversion charts.
Starting point is 00:18:25 And so it says, okay, if I did 75 pounds on my bench press and I did it eight times, you can just run an estimate and say, okay, you're probably going to be able to bench about 95 pounds for one rep max or something. So that's a very easy conversion chart. So just pick a low that you feel comfortable with, but it's kind of heavy, but not like crazy heavy and do as many repetitions as you can, what a like crazy heavy and do as many repetitions as you can, what a really good technique, and then look what that number would be. So conversion safer than doing one repetition maximum. For the general public who has again no coaching, it's safer.
Starting point is 00:18:56 For a professional athlete, it's not any safer, but or not even a professional athlete, but a trained person with a coach. But for most people, yeah, that's a good way to go about it. You can also just kind of do it with feel in the sense that say you want to do a set of five repetitions and you do the load and you think, I cut it down one or two more. And then you kind of have an idea of what that number is going to be. If you think, man, that last one, I had to kind of really, really, really get after it, then maybe just call that
Starting point is 00:19:26 that number, right? So you don't have to get overly concerned. In fact, when we start getting into these number ranges, you're going to see that they're all ranges. We're not going to give a specific 95% for one of these exact reasons. It's not that precise for most of them. In fact, some of them like hypertrophy have enormous ranges that you'd like almost can't miss. So the intensity in that case doesn't even matter for the most part because that's not the primary determinant. Some of these you're going to see intensity as a determinant. Some of these you're going to see volume is the true determinant. So intensity though is a second one. Choice was the very first one, manipulative variable,
Starting point is 00:20:04 intensity was the second one. The third one was first minute variable variable. Intensity was the second one. The third one was what we call volume. And so this is just how many reps and how many sets are you doing, right? So if you're gonna do three sets of 10, that volume would be 30, right? Five sets of five, that volume is 25. It's just a simple equation.
Starting point is 00:20:17 How much work are you totally doing? The next one, pass that is called rest intervals. So this is about a time you're taking in between typically a set. Then from there you have progression, which is what we started to talk about this progressive overload. Are you increasing by weight or reps or rest intervals
Starting point is 00:20:33 or complexity or whatever. So all of those things can be changed as a method of progression. And so maybe you wanna go progressing from a single joint exercise like a leg extension on a machine, and you want to progress by moving to a whole body movement like a squat. That and of itself, you don't have to change the load
Starting point is 00:20:56 or the reps or the rest. That is a representation of progressive overload. And it's probably a pretty good place to start because number one, especially for beginners, you want to make sure that the movement pattern is correct. Don't worry about intensity, don't worry about rep ranges or any of these things, you need to learn to move correctly, and you need to give your body some time to develop some tissue tolerance, so that you're not getting overtly sore. In general, soreness is a terrible proxy for exercise
Starting point is 00:21:22 quality. It's a really bad way to estimate whether it was a good or a bad workout, especially for people in that beginner to middle to moderate. In fact, even for our professional athletes, we do not use soreness as a metric of a good workout. It's a really bad idea for a bunch of reasons. On the same token because stress is required for adaptation, you don't want to leave with a gem and feel like, I don't really do much. There has to be there. So if you think about soreness on a scale of one to ten,
Starting point is 00:21:50 you probably want to spend most of your time in like the three. You mean post exercise? Yeah. In between workouts. Totally. And I know we'll talk about recovery extensively later, but if one body part or set of body parts is sore, is that an indication that one should stay out of training? I would imagine the answer is no. Right. In most cases, and secondarily to that, if a particular muscle is sore, does that mean that muscle is not ready to be trained again?
Starting point is 00:22:20 Yeah, the answer to both of those is the same, which is no. You can certainly train a sore muscle. You need to, I guess, have a little bit of feel on that, right? So if you're a sore of like, okay, like when you're moving around a little bit and you're like, man, this is a little bit sore, you can train. If you're like, I can't sit on the couch without crying because my glutes are so sore, like we probably don't need to train again, right? Does whimpering count is crying? Yeah, in that particular case, I'd say, you've actually gone to a place of detriment,
Starting point is 00:22:52 because now you're gonna have to skip a training session. And now you're behind, so you're actual total volume, say across the month, is actually gonna be lower, because you went way too hard in those workouts, had to take too many days off in between. You're gonna see that you're gonna cover less distance over the course of a month or six months or even a year. So you wanna walk a pretty fine line, and for most people, I would say,
Starting point is 00:23:12 hedge a little bit on the side of less sore than more sore. Because frequency is very, very important for almost all these adaptations. Training frequency. Which is the last modifiable variable, right? Frequency. Which is how many times per week are you doing that thing? all these adaptations. It's training frequency, which is the last modifiable variable, right? Frequency. Most of how many times per week are you doing that thing?
Starting point is 00:23:29 So those are kind of our global things that we can play with. So when I'm trying to manipulate and you can get strength versus hypertrophy, or you know what, I want like a little bit of both, all those variables are the things that are going through my mind. Which one do I need to move in which direction so that I can get this outcome and not this outcome over here? For example, some folks might want to get stronger, but not put muscle mass on. Some folks are just kind of want both.
Starting point is 00:23:55 And that's a lot of the general public. I want to get a little stronger and a little bit more muscle gray. But there are instances where people for performance reasons or for purely personal preference like, I don't want to get any more muscle. Great, but I want to get stronger. Awesome. If you manipulate those variables correctly, you can get exactly that. Very little development of muscle size and a lot of development and strength.
Starting point is 00:24:14 This is why we continue to break road records in sports like powerlifting and weightlifting that have weight classes. There's a top number that we can hit in terms of body size, but yet we continue to get stronger and faster. So this is very possible if you understand how to manipulate all those variables. So that being said, we can start off with, you wanted to go strength and I think- Yeah, strength and I love that you mentioned the fact that it is possible to increase strength without increasing muscle size, at least not dramatically because I think it's not just
Starting point is 00:24:41 weight class athletes. I know a lot of people who, for aesthetic reasons, they'd like to be stronger. They're hearing that having strong bones and strong muscles and tendons, it's not just weight class athletes. I know a lot of people who, for aesthetic reasons, they'd like to be stronger. They're hearing that having strong bones and strong muscles and tendons, it's great for longevity and for avoiding injury and so many other features of life. And yet they don't want to fill out progressively larger
Starting point is 00:24:58 and larger sizes of clothing. And we can go harder to the mechanisms on that piece if you want. We can save that and come back to it. Sure. What I'd love to both, what I'd love to know, if we could define some of these modifiable variables in the context of strength. So let's say, I were somebody who I come to you and I say, and let's just say for sake of balance here, because she actually does do some weight training. I bring my sister in and I say, me and my sister both want to get stronger.
Starting point is 00:25:29 What modifiable variables should, how should we modify the variables? Love it. All right, great. I'm going to do inception on you one more time. So one of my other laws, this won't be fast, I promise, of strengthening conditioning, is in general, the default is all joints through all range of motion. So this is important because it's gonna answer your very first question on this strength category.
Starting point is 00:25:51 So in general, the ankles should go through the full range of motion, the ankle, the knee should go through the full range of motion, the knee, the hip, the elbow, et cetera, et cetera, right? Across the workout, not in a single movement. Well, I would hope. Unless there's an amazing exercise I haven't heard of.
Starting point is 00:26:06 Well, there are some exercises that we're gonna call more full body, think about a full snatch. Like you're gonna take a lot of your muscles, a lot of your joints through a lot of range of motions. Other ones like an isolation, we call these single joint exercises, so imagine a bicep curl. You have one joint in that particular case,
Starting point is 00:26:23 the elbow moving, the shoulder and everything else is pretty much stable. And this is how we'll differentiate multi-joint from single joint movements. But yeah, so across, I would even say it doesn't even have to be the day, but maybe throughout the week, try to get every joint through full range of motion.
Starting point is 00:26:40 Now, a couple of quick caveats to that. I am not advocating using full range of motion and allowing really bad exercise technique. So when I say full range of motion, that's the default. That doesn't mean every single person can do that for every single exercise. It means that's where we should be striving to, and that's our starting point.
Starting point is 00:26:58 You're gonna see a lot less injury and a lot more productivity out of your training sessions. In fact, the science is fairly clear on this one. Strength development as well as hypertries generally enhanced with a larger range of motion of training. And the mechanisms are somewhat understood on that. So that being said, if you have to get into, say, a position with your say low back,
Starting point is 00:27:21 the spine is a very good one. You're in general, the spine states very neutrals, we call it. So no no flexion, no extension, especially in the lumbar region. So if you, if you're doing a, say a deadlift and in order to take your knee through a full range of motion, a deadlift, you have to compromise your back position. That's no point. So caveats, they're aside, don't kill me. Like in good positions. Don't kill yourself. Yeah. more importantly. So why that matters is if we walk through strength, the very first thing I'm going to go through is the exercise selection.
Starting point is 00:27:51 So let's choose an exercise which ideally has a full range of motion or close to it that doesn't induce injury for you that you can still maintain good neck and low back and position and everything else. You feel comfortable with so you can feel strong, but you don't feel like, oh my gosh, if you've never snatched before, having you do a snatch for a maximum, even, you know, 75%. Like, it's a terrible idea. You're not going to feel confident it's going to be a train wreck. I would rather put you on a machine bench press. So even though I feel stable, I feel safe here, and I could just express my strength.
Starting point is 00:28:23 So exercise choice in generally, in general, full range of motion, and you wanna kind of balance between the movement areas. So this is an upper body press. So this is pushing away from you, bench press, and things like that. Upper body pull, pulling an implement towards you. Bent row, pull up. The pressing should be horizontal,
Starting point is 00:28:41 so perpendicular to your body, as well as vertical. So this is lifting away over top of your head, lifting away from you. The pull version is pulling horizontal to you and pulling vertically down, pull up, things like that. From the lower body, we typically call these hinges. It's sort of a funny muscle thing that no one's going to laugh at, like maybe me and you here, is we'll categorize muscles as our movements, exercises as pushers and pulls, right? So like a squat is tends to be a push because you're pushing away the ground.
Starting point is 00:29:11 A deadlift is a pull because you're pulling the implement up to you. But in reality, every single exercise is only ever a pull. Because muscle doesn't push things away, muscle can only contract and pull on itself. And so again, super nerdy thing they like, most people are like,
Starting point is 00:29:25 yeah, and everyone's like, that's so dumb. No, but I think it's a really important point because it also speaks to something I think we'll get into later, which is that, you know, posterior chain anterior chain. Totally. And if that's mysterious to people,
Starting point is 00:29:36 it'll become clear before long. Posterior chain anterior chain makes a lot of sense to me because of the way it's grounded in the firing of motor neurons, which is ultimately what controls muscles. So it's also, I think, there are all the time. Exactly. So it also depends on the lens through which one looks at life and exercise.
Starting point is 00:29:53 Of course, my lens is primarily neuroscience. So, but I realized that the importance, I like this idea of pushing perpendicular to the body overhead, pulling both toward the body and from overhead. That just makes really good intuitive sense, especially since a lot of people were just listening to this and not watching it. So, in your minds, folks, you can think about pushing away like a punch or overhead, like lifting something overhead and then pulling toward your midline or toward your body rather and then pulling yourself up like a pull up in PE class for those
Starting point is 00:30:25 of the... Yeah. So the lower body is the same thing, right? It's some sort of pushing away, like a squat or a split squat or a lunge or something like that. And then some sort of, again, we'll call pull or hinge. So a deadlift or a Romanian deadlift or a hamstring curl or something where you're contracting and calling pulling the thing. And you could split these into like a thousand different categories. If you're really in that field, you're gonna wanna add a bunch of other ones. But that's just like a rough conception.
Starting point is 00:30:51 So if you're going to do a single workout, you could choose four exercises. And you could choose one of each. One press, upper body press, one upper body pull, one lower body hinge, one lower body press. And that would be like a decently well-rounded exercise. That's your exercise selection. And if you're taking those through a full range of motion,
Starting point is 00:31:11 you're at a pretty good spot. It was close as you can. The next one is intensity. So if you wanna develop strength, this comes back to one of my favorite sciences of all time, what happens to be a nerve guy, actually. And generally, I like to shit on nerves as much as I possibly can,
Starting point is 00:31:23 because I'm a muscle guy. But I have to give Hennamann some credit here, right? And I know you know who that is. Hennamann size principle. Yeah, of course, right? So this is a series of papers, I think it was a nature. At least some of them, yeah. Yeah, in 1954, 56 or something,
Starting point is 00:31:39 you can fact-check me, I'm sure you will. But he basically outlined this idea that, okay, there is a certain recruitment threshold needed for neurons to fire. And we have muscle fibers in what we call fast twitch muscle fibers and slow twitch muscle fibers. And in general, you're going to activate the slow twitch on this first because they tend to be associated with low threshold motor neurons.
Starting point is 00:32:00 It's not exactly that way, but it's close enough, right? Well, the only way that you activate some of these higher threshold neurons is to demand the muscle to produce more force, and it's fairly specific to force, right? It's not something you can do over an endurance thing, right? Unless it gets really extreme and particularly happens. So in general, the only way to use these big chunks of your muscle, which are incredibly important for aging, by the way, one of the major problems we have with aging developing, or development of aging-related issues with muscle is the fact that we lose fast switch fibers preferentially. And then we have major problems as we go down the line because we've lost a big chunk of our strength in size.
Starting point is 00:32:38 So you want to make sure these fibers stay alive and intact. Okay, so if that being said, the only way to develop strength is then to challenge the muscle to produce more total force. If you are fairly untrained or new, I guess I should have stated this all at the beginning as well. One more inception that I'll stop. When it comes to this level of detail, of exercise prescription, a fairly untrained person is going to respond basically the same to every single thing you do. In fact, we've done this in a lot of many times.
Starting point is 00:33:08 We've done training studies doing things like 30 minutes of cycling and seeing huge increases in muscle strength and size, which is not a prescription for most people to use a precise, but people that are really untrained, if you did plyometrics or strength training or endurance running, they all just get better at everything. So that caveat kind of aside, if you want to be more intentional and more specific to the goal of strength, you need to produce more force. Specificity matters, right? So we have size principle to help understand this. And we have our laws of specificity, which say said principle, right? Specific adaptation to imposed demand. So the adaptation you get or the result of your training is going to be a reflection of
Starting point is 00:33:51 the demand that you imposed. So if you want to get stronger, you need to impose a demand of strength, not repetitions. So this has to be the load has to be very high. In general, you're probably looking at above 85% of your one-retting max. If you're moderately trained, maybe 75% will work lowly trained again, everything works. But in general, we wanna be pressing a load that's very high.
Starting point is 00:34:16 So because the intensity demand is so high, that is going to enforce you to do a low repetition range. You can't do 12 reps at 95%, that then it wouldn't be 95% of your one or a max. So by definition, true strength training is really going to be in like five repetitions per set or less range. That's where most of it's going to occur for specificities. So we've covered choice and intensity and repetitions, right? The total amount of sets that you do
Starting point is 00:34:46 is really kind of up to your personal fitness level, right? If you did as little as like three sets for exercise, that's probably enough. Work sets. Totally, yeah, totally work sets, right? So get fully warmed up and build up to that 85%. Don't just walk into the gym and throw 85% on them go. Thank you, that's an important distinction.
Starting point is 00:35:05 So work your way up. Do some, like a very classic warm-up thing would be like a set of 10 at 50%, a set of 8 at 60%, a set of maybe 8 again at 70%, and then maybe like a set of 5 at 75%. So two or three or four sets kind of building intensity and lowering the rep range and then you would go after your two or three working sets also In terms of rest intervals now because we're trying to the primary driver of strength is intensity It's it's not the volume right it's the intensity so in order to maintain that we have to do a low repetition range But in addition, we also have to have a high rest interval.
Starting point is 00:35:45 Because if we start to, if we have any amount of fatigue in the curve, and we have to then reduce the reps or reduce the intensity, we've lost the primary driver. We've lost that main signal. So the number we're going to throw out typically is like two to four minutes. So imagine you did your setup bench press, and you did five repetitions at 85%. You probably want to rest two to four minutes before coming back to the bench. You did your set of bench press and you did five repetitions at 85%.
Starting point is 00:36:05 You probably want to rest two to four minutes before coming back to the bench. That doesn't mean you have to sit there on your phone. Like, in fact, please don't. Like, everyone will thank you for not doing that. I promise. You can engage other muscle groups. This is what we call super setting.
Starting point is 00:36:19 So you're doing your bench press and while that two minute clock is running for your chest to rest, you can go over and do your deadlifts. And so you can kind of move back and forth and this is how you can make strength training at not seven hour workout. If you're a professional athlete, you're going to take that time because you want to maximize the outcome. We've done this actually in our lab too.
Starting point is 00:36:41 Super sets will reduce the strength gains, but by a tiny amount. And most of us don't care enough relative to it's going to triple the length of your training session. It's not worth it. So for the average person, I will tell them, yeah, super set. For someone who's trying to break a world record and weightlifting or powerlifting, I don't super set. Interesting. Yeah, I think I've found that I don't recover particularly well from strength and hypertrophy training.
Starting point is 00:37:08 Like in the workout or the next day? From workout to workout. Unless I keep the total duration of those workouts, I like to say no more than 60 minutes of work, of real work. Yep. Maybe 75. Past 75 I find that I just start to, I have to introduce additional rest days or I just get weaker over time. So I'd set a limit at 50 minutes and then I usually
Starting point is 00:37:34 violate that limit and end up doing 60 minutes. So I'm excited to hear that one can superset exercises as long as they work different muscle groups, of course. Right. So I wouldn't want to do like bench press and overhead press superset it because you can have we can eat. I think that's those without saying for most people, but just to point it out. But that I could do some push pull, push pull without compromising total intensity that much. And I certainly would be willing to give up a rep here or there, a few pounds
Starting point is 00:38:05 here or there. And ask whether or not in doing that one gets any even tiny bit or more of additional benefit in terms of cardiovascular work because I imagine after all, even a one rep max, which I've never done as I mentioned, but let's say I get three reps on the overhead press and then I get four reps on a weighted pull-up and I'm going back and forth. No doubt gonna be breathing harder than if I was sitting there texting away on my phone in between sets. Yep, of course. Yeah, and in fact, in general,
Starting point is 00:38:39 one of the things that I'll present in my class is a giant list of, in fact, on the top is all all these different exercise adaptations I started the conversation with. And on the vertical column are, as many of the physiological potential adaptations one would get. So changes in endogenous pH, blood pressure,
Starting point is 00:38:58 lymphatic changes, bone density, all these things, right? And you just have this giant list. And then you can run on matrix, and you can start to look at, okay, if I do speed training, am I gonna see changes in the nervous system? Well, like very much so, right? That's the primary actuar reason those things work.
Starting point is 00:39:13 Very little change in the muscle system. It's almost exclusively explained by the central or peripheral nervous system, right? On that same token, are you gonna expect many cardiovascular adaptation from speed? And the answer is no, because although we didn't cover it,
Starting point is 00:39:26 speed is very low intensity, very low rep range, very high rest. Well, as you go to strength, and then you go to hypertrophy, you start seeing more and more increases in cardiovascular adaptations because you're doing exactly that, right? You're starting to reduce rest, and you're starting to increase volume. But you're going to lose things like bone mineral adaptations, because the load serves to increase volume. But you're gonna lose things like bone mineral adaptations
Starting point is 00:39:46 because the load serves to go down. So you can look at this matrix and kind of understand if I'm a person who wants to maximize the adaptations I get across my entire physiology for the least amount of work. You can choose these different adaptations to go after that are gonna kind of land on these things, right? And exactly as you mentioned, if you're going to take five minutes rest between each rep.
Starting point is 00:40:09 So let's say they extreme, you're going to do three sets of one repetition for strength at 95%. You're going to take probably five, maybe seven minutes between each attempt. You better not expect many changes in your resting blood pressure, that there's no cardiovascular strain there. You're going to put it together in a circuit, where you're going to lose some potential strength adaptation, but you're going to gain something there. So all these things are, it's not about good or bad or right or wrong, it's always about
Starting point is 00:40:34 what advantage you want and what disadvantage do you want. And I can cut like really end to the chase here on one of these things, because we'll get to this eventually. If you want to know the ones that are going to generally give you the most physiological adaptations across the most categories, you're almost always looking for a perch-be-type of training, and then this anaerobic conditioning piece that's gonna hit the most systems at once.
Starting point is 00:40:58 That's great to know, and we should definitely go a little bit deeper on those types of what the modifiable variables are for those categories, because I think that I'm guessing the vast majority of people want to be a bit stronger, maybe add some a little bit of muscle or more, make sure their heart is healthy and etc. This is wonderful and I think it's clarifying certainly a lot for me. So, for strength, I guess training frequency. So what should determine training frequency?
Starting point is 00:41:27 And I had the great benefit of a long time ago when I was in high school actually, I paid for a session over the phone with Mike Menser. Oh, you know, the Mike Menser. We got to be friends over time. Hi, I'm Tensity Training. At the time I was pretty young and my mother kept saying like,
Starting point is 00:41:44 why is this like grown man calling the house? And we would talk had the time I was pretty young and my mother kept saying like why is this like grown man calling the house. I mean we would talk all the time about training but he tried to convince me to train once every five to seven days. Very few sets, very high intensity. And I must say it worked incredibly well. Sure. I think with my recovery quotient, which was not very good, I think has improved over time, but it was not very good. It was remarkable. But of course, this was a time when I was, you know, full of the most animalism I've ever had on my own version of animalics. I was, you know, really had a long arc of puberty. And you were untrained.
Starting point is 00:42:20 And I was mostly untrained. I've been running cross country and skateboarding and playing soccer. So all the things that are like the antithesis of great muscle. It was literally and people will probably say impossible. It was something like 40 pounds of muscle inside of 12 months. It was crazy. I would believe it. I would believe it.
Starting point is 00:42:36 And so then of course that stopped working over time. And then you start going down the odyssey of trying to find the thing that's going to work that well. And you eventually realized that it was because you were untrained right. So training frequency is is crucial. Let's say that people are doing these whole body workouts as you describe them not alternating upper body lower body because there's so many different splits that we've talked about doesn't probably doesn't make sense to go into splits in in now. But how often can and should one train a muscle? And how do you know if a muscle is recovered locally
Starting point is 00:43:11 and how do you know if your nervous system is recovered systemically? Okay, this is a bunch of really interesting questions. I'm not sure exactly what right you wanna go. So I'll start here. As I mentioned earlier, soreness is not a good parameter of exercise quality because some types of training are going to induce more soreness and some are going to induce less.
Starting point is 00:43:29 That's important to this conversation because when you ask about how do you know if a muscle is ready to train again, one of the question is what are you training for? If you're training for hypertrophy, right, muscle size, muscle growth, we need to hedge towards recovery because what you're trying to do is cause a massive insult there, allow then protein synthesis to occur, building a new tissue which takes time 48 to 72 hours, like kind of about a minimum, that process needs to occur. If you're doing actually more strength, and this is a differentiation between hypertrophy and strength, then you didn't induce actually much damage. In fact, you're generally not going to get very sore
Starting point is 00:44:05 from true strength training, very little. Unless you get really heavy, you did a lot. The primary driver of hypertrophy is not the same primary driver of strength. We talked about that already. That's intensity driven for hypertrophy. It's not intensity. So because we have different mechanisms,
Starting point is 00:44:23 we have different outcomes, even though they're closely aligned. Strength is not going to cause a lot of soreness. Therefore, intensity is the driver. Therefore, frequency can be as high as you want. So you can train every single day the same exact muscle if speed or power or strength are the primary training tools because you need stimulus there. Skill is well, right? Practice. training tools because you need stimulus there. Skill is well, right? Practice that, you know that as much as anybody,
Starting point is 00:44:48 developing a new motor pattern requires a lot of repetitions, right? You don't need a tremendous amount of rest. That's not a damage thing, right? It's a repattering issue. So strength training, in fact, if you look at, again, true strength professional athletes, they're going to train the same muscles basically every day.
Starting point is 00:45:05 Wow. They're going to squat every day. And is that because the primary mode of adaptation is recruitment of these high threshold motor units? So it's mainly neural. No. So everyone's going to say that and this is where I get all feisty. Well, I'm not saying that.
Starting point is 00:45:19 That was actually, there was a question mark there. Okay. Okay. If we were online putting comments, there would be a question mark. We would have fought. Right. I would have blocked you. I'll just get that. You already blocked. No, probably twice. Um, okay. The early adaptations to exercise, especially strength training are hedged towards the nervous system. No question about
Starting point is 00:45:41 it. People always say central nervous system, but it's probably more peripheral, right? Whatever. Symantex probably a bit pedantic. It's nerve. If you train today, tomorrow morning, you're not going to wake up with a actually increase in contractile proteins and muscle. Your muscle might be a little bit bigger due to some acute swelling, but you could have a pretty acute that persists, change them, and the nervous system will call it, that allows you to be stronger, like within a couple of days. Sustained hypertrophy is probably more
Starting point is 00:46:10 along the lines of four weeks, where we can see that, right? We can actually see changes like in the ultrasound. Now, you're making changes immediately. That protein synthesis process is happening, like very fast, and it's gonna last, it just takes us time to measure it in terms of a noticeable
Starting point is 00:46:25 change in your whole muscle size. So that being said, the first four weeks we typical say are primarily nervous system. After that, now we're starting to see most of the changes coming from the muscle side of the equation. So with strength development, it's a combination of three areas. In fact, all muscle contraction has these same three things. It starts off with some signal, right, from somewhere in the body, whether it's all the way up the top or at the level of the spine, depending on if this is a reaction or an actual conscious control. From there, that some signal has to tell the muscle to contract.
Starting point is 00:46:59 So signal is one, two, it's muscular contraction, and there's a lot of variables inside the muscle tissue itself that determine its functionality. And so if we took an individual biopsy and took a muscle fiber from you and took one from me and we took those muscles out and put them in a petri dish. And I tied one end to a force transducer, the other end to a thing that pulls it. And we soaked it in a bath of calcium and a bunch of other stuff. Even if they were the same size, your fibers might contract a lot faster than mine, even relative to size, or not, or slower, or there's various properties. So the intrinsic fibers themselves
Starting point is 00:47:33 determine a lot of functionality. From there, muscle fibers don't cause movements. Muscle fibers simply contract. They're all surrounded with connective tissue, and that's all surrounded with a bunch of more connective tissue, and that all surrounded to a muscle. That muscle is then surrounded surrounded with connective tissue. And that's all surrounded with a bunch of more connective tissue. That all surrounded to a muscle. That muscle is then surrounded with more connective tissue.
Starting point is 00:47:48 That all comes together into a giant tendon that tendon attaches to the bone. It's pulling on those tendon that actually move the bone that caused human movement. So that's area three, area one, the nervous system area two, the muscle contraction area three, some sort of connective tissue thing. Change has happened at all three of those levels. And we're not even now talking, well, even you entered the discussion of biomechanics and you changed, say, the penational angle of the muscle, which is the angle at which the muscle fibers lay relative to the bone.
Starting point is 00:48:16 Right? So this is basic mechanics. Is it pulling perpendicular to the bone? Is it pulling horizontal to the bone or some sort of angle? All of these things determine human performance. So when you're talking about, again, that strength development, you can see tremendous improvements in total force production by manipulating all of those areas and you have not touched changes in muscle size. If you change muscle size in a true sustained fashion, whether this is
Starting point is 00:48:42 circumplasmic or to contractile proteins, you have given yourself more opportunity to produce more force. It doesn't guarantee you produce more force. Bodybuilders are not stronger than power lifters, even though they have more muscle. But bodybuilders are probably stronger than most people. So there is a relationship between muscle size and strength. It's in this not a one a one to one guaranteed ratio. And that's generally because the, although the muscle has been aided, they may have not
Starting point is 00:49:10 changed the biomechanical considerations. They may have not changed the connected tissue nor the nervous system stuff. And so that's why we see this giant relationship. That R value is pretty high between strength and hypertrophy. But if you really want to get to the ends of it, it's not. And that matters to your actual question 10 minutes ago, because again, you can train strength daily on the same muscle. But if you want to allow for that process of contractile proteins to add and grow, then
Starting point is 00:49:38 you're going to have to allow some recovery. Because if you go back into that muscle too soon, you're going to blunt the response, you're going to stop it, you're gonna stop it, you're gonna cut it off. You have all kinds of problems going on in the cell that are gonna just attenuate that growth response. So, I gave you the answer for strength training. The answer for hypertrophy is probably less than three out of 10 on level of soreness, so you can go again.
Starting point is 00:50:01 In general, you're probably looking at 72 hours is the optimal window. So if you trained your, your shoulders on Monday, you probably would don't want to train them again on Tuesday. If I purchased the goal, maybe Wednesday, maybe Thursday's best. So something like an every two to three day window is probably, and we know a little bit more now
Starting point is 00:50:22 about why that is. The gene cascade, the signaling response happens, well, the signaling happens instantaneously, right? Within seconds, the gene cascade is probably in the peaked in the four hour window, like depending on which gene you want to look at, but it's just kind of a snapshot. But the protein synthesis process is 24 to 48 hour thing. And so it tends to kind of look like let that thing finish and let that signal go back to baseline,
Starting point is 00:50:47 and then hit it again. And then hit it again. And now as long as you're providing the nutrients, the recovery should happen. And you should be able to sustain the same work output in the training session. So the stimulus stays high, and the recovery's there, and you can now continue to grow muscle.
Starting point is 00:51:04 You mentioned 48 to 72 hours for hypertrophy. What if, for whatever reasons, the training split, lifestyle factors, et cetera, somebody say, let's use your example, trains shoulders on Monday. Ideally, they would train them again on Thursday in their particular instance, somewhere when's air Thursday, but they don't. They wait until Saturday or Sunday for whatever reason. Maybe it's more compatible with their work, work, and other exercise schedule, whatever the reason.
Starting point is 00:51:38 Are they actually losing hypertrophy that they gained or they've missed a window to induce further hypertrophy? It's probably better to think about it the latter. It's not that you've lost, it's just you've just kind of lost an opportunity to make more progress. I will save you a little bit and kind of going back to your hit program. This is the original high intensity training, the mencer thing, right? Which is not...
Starting point is 00:52:02 The hit with one eye, not the high-intensity interval training, but high-intensity training. Like the one set to absolute failure, maybe two for each muscle group. 20 minute workouts. Dividing your body into three into a three-way split, and then literally training like six times a month, which most people think that is absolutely crazy.
Starting point is 00:52:21 There's no way that's gonna work, and I can tell you, if you are untrained, you grow like a weed. Just if you train hard enough. Even if you're trained, look at the people who might train. He put a lot of bodybuilders on really high levels. Now, they had the same similar help you had at that time frame.
Starting point is 00:52:37 Wait, to be very clear, I was not taking exhaustion as Santa box. In fact, I was- But your endogenous was just as good. I probably was. I wasn't measuring my levels there, but I probably would. I grew easy and in general, I tend to grow pretty easily from weight training.
Starting point is 00:52:51 I should say that to Mike's credit, and I think this is an important message, that he was the one who really said, look, unless you're going to make a professional career out of it, do not run the health hazards of exogenous hormones, you know, certainly not at your age. So he deterred me from that, which is great because it never entered my mind. It just was one of those things where Mike Mencer said don't do it and he had clearly done it, right? And so he's speaking from an informed place, it never entered my mind. But also I was what was really wild as I was continuing to run across country.
Starting point is 00:53:24 And so there was a trade-off there at some point. A bit of an inter-year. But when you're young, you can get, many people can get away with what at this age would surely place me into a state of overtraining even at low volume. Well, I mean, like the whole field on interference effects has changed quite a bit recently, which we can come back to if you want. But just to finish out the idea here with that last question,
Starting point is 00:53:49 if you wanna take five days or six days in between each mouse group, you can do that. In fact, if you look at the research, it's gonna show that frequency is not that important. It's not that it's not important, but it can handle changes, as long as you get to the same total volume. So you can do that.
Starting point is 00:54:07 You just have to do a lot more work in that one workout. If you care about the six week, eight week thing, if you're like, I'm in this for the next 60 years, it's probably okay, right? But it can be there that the challenge with splitting up your training sessions for hypertrophy into smaller numbers, like once or twice a week, it's just difficult to get that number. It's typical to get that volume done. Volume wise, the more recent meta analyses are going to say that you're probably looking at around 10 working sets per muscle group per week.
Starting point is 00:54:42 It seems to be kind of the minimum threshold that you're going to want to hit. So if you did three sets of 10 at your shoulders on Monday, three sets of 10 shoulders Wednesday and three on Friday, that's nine working sets. If you wanted to do three different shoulder exercises on Monday and hit your nine sets, it's not really actually going to be that much different. The problem is 10 is kind of the minimum. You probably want to look for more like 15 to 20, and in fact, well-trained folks, 20 to 25.
Starting point is 00:55:12 That becomes very challenging in one workout. In fact, defunctal, you're not going to be able to do it, right? And so that is where it's not the frequency that looks like it kills you. It's just the fact you have got to get because the total driver of strength is intensity, but the total driver of hypertrophy is volume. Assume you're taking it to fatigue, right, or muscular failure. So it's just tough to get enough done.
Starting point is 00:55:32 If you can, and if you want to set your schedule up that way, like you probably remember, if you do those types of training sessions where you're just going to completely exhaust a muscle, it's going to be, it's going to be sore for a while. You're probably not going to come back. And that's sort of the logic behind that was let's take this thing to tremendous failure and give it six days to recover. It can work. It's just not the best.
Starting point is 00:55:56 I think it's the one I want to think about it for most people. It's also hard to do those workouts without a training partner. If you really want to do them correctly and stimulants and headphones and all kinds of other things. Yeah, well, anyway, stimulants are not, I don't certainly don't recommend those. It may be a cup of coffee or two if that's your thing. But, and maybe some of the safer supplements, but certainly not sorts of stimulants that the guys in the 70s and 80s were saying or still use. You talked about repetition ranges broadly for strength training. So five or less, you said frequency could be as often as every day, rest two to four
Starting point is 00:56:31 minutes, maybe even longer if you're going for one repetition maximum, for hypertrophy. What are the repetition ranges that are effective? And what are the ones that are most effective if one is trying to maximize some of the other variables? Like, people don't want to spend more one is trying to maximize some of the other variables? Like, people don't want to spend more than an hour to 75 minutes in the gym, because I think that while the ranges might be quite broad as you alluded to earlier, there's the practical, there are the practical constraints. So what repetition ranges or percent of one repetition maximum, should people consider
Starting point is 00:57:04 when thinking about hyperstripe? Right. The quick answer there is anywhere between like five to 30 reps per set. That's going to show across the literature pretty much equal, I purchase the games. And we can have a really interesting discussion about why that is, but I'm just remembering one thing from a second ago, I want to give a better answer for the frequency. You can do every single week for strength, or every single day for strength. If you want though, like what's probably minimally viable too, twice per week, per muscle.
Starting point is 00:57:32 So hamstrings, strength, twice per week. That's a good number to get most people really strong. You can do every single day. You don't need to though. So I wanted to make sure that, like I wasn't saying you have to train a muscle, 85% every single day to get it strong. Two was a good number three is great, but probably even two is really effective. Got it This explains the high frequency of
Starting point is 00:57:53 Training for strength athletes that's always mystified me. Yeah, and the very long workout to make sense because very long Everything even trained twice a day like even little squat in the morning squat in the afternoon every day with They're eating in their sleep and they probably don't have time for anything else. That's why they're pros. So that's a job, right? That's what they do. So, yeah, your hypertrophy. Strength training, programming is somewhat complicated, right?
Starting point is 00:58:17 Because of, that's not the danger, but you're going to have to pay one way or the other, right? The risk is a little bit higher because the load's higher, and you have to be a little more technically proficient. When it comes to hypertrophy training, the way I like to explain it is it's kind of idiot proof. The programming is idiot proof, the work is hard though. So, you're here's your range. Anywhere between five reps and 30, can you hit somewhere in there? Perfect. It's all equally effective. You can't screw that up. The only caveat for hypertrophy is you have to take it to muscular failure. And you need enough rest for the adaptation in protein synthesis to occur?
Starting point is 00:58:51 Yep. And if you recover faster, you can maybe do it more frequently. And if you don't, maybe less frequently. By that logic, should people perhaps experiment and figure out what repetition range allows them to recover in concert with the training frequency that they can do consistently. My recommendation is I think you should actually use the repetition range as a way to have some variation because most people don't want to go into gym and do three sets a 10. They're going to get very bored very quickly. And so I think you should actually intentionally change the rep schemes
Starting point is 00:59:24 for simple sake of having more fun. It is a very different challenge. The mechanisms that are inducing hypertrophy are different, but there's only a maximum amount of growth that one can get. And so you have, as best we think it now. And some people actually will dispouse that we know really clearly about the mechanisms of most hypertrophy. We don't.
Starting point is 00:59:43 It's still very much a guessing game. But the three most likely drivers are one metabolic stress, two mechanical tension, and then three muscular damage. You don't have to have all three. One is sufficient. You can have a little bit of one or two, and you can cut it, so you get it to play here.
Starting point is 01:00:01 We've already talked about the muscular damage. Again, it's very clear, more damage is not better, but it is somewhat decent proxy, right? Like, it's getting a little bit of soreness is good. You don't get so sore, it's compromising your total volume, all right? Mechanical tension is kind of like strength. And this is why if you do even set to five or eight and you're kind of close to that strength range, you will gain a little bit of muscle, not optimal muscle gain, but you're going to gain some because everything in these physiology isn't cut off at four reps and then five reps is a different thing, right? It's always a blend, so think of it as like a fading curve.
Starting point is 01:00:33 As you get closer to the end, it fades less effective. As you get closer to the middle, it's more effective. Anywhere between eight reps per set to 30, it's equally effective. Past 30, it's going to blend out. Past 8 to 5 to 4 to 3, it's going to blend, you know, less or there. So metabolic stress is one that damages the other, or sorry, mechanical tension is the one that's heavy. I muscle damage is the other one.
Starting point is 01:00:58 The third one is metabolic stress. And this is a bit of an area of scientific contention, but something's there. I know something's there. We're just kind of fumbling to figure out what exactly it is. And this is metabolic stress is the burn, right? It's there.
Starting point is 01:01:15 It's why blood flow restriction training probably works. That's done very light. So there's no mechanical tension. There's very little damage, but somehow it induces a good amount of hypertrophy. Very painful. Oh boy. I tried this, I've a friend former special operator who was on the East Coast and took
Starting point is 01:01:32 me through a blood flow restriction training protocol in the park. I don't think I actually cried, but you probably did. But I might have cried out once or twice. It was unbelievable, especially the lower body movements. Yes. Now it was a humid day. I'll clean a little bit of gel. No.
Starting point is 01:01:51 No. But it was brutal. It was really brutal. And I also- Do not the best of your life and it's still brutal. Okay. Well, that makes me feel a little bit better. It was intense.
Starting point is 01:01:59 And people should know that it is important to use the proper cuffs for these things. I don't have any relationship to any of the companies that sell these cuffs, but the reason is that you actually need to block particular avenues of blood flow. You can't simply cinch off a muscle. You can't turn it get a muscle in train. You can actually kill yourself that way. Yeah, you can get a blood clot. Yeah, and so if you're interested in blood flow restriction training, I imagine you have some content about this or will at some point, but also there are resources online that people can pick up. A question about hypertrophy training that I think many people are wondering about, trained to failure or don't train to failure, assuming good form.
Starting point is 01:02:38 Yeah, assuming good form. Great. The answer is both. So you want to train to failure, but you don't need to go to extreme failure. So you don't need to necessarily go to that like, a partner has to lift the barbell off my chest, but you have to get close. You have to drive either heavy, stress, damage, or pump. And so I really easy practical way to think about this. I heard Mike Gzerre-Till runs a company called Reathers Nuts Periodization years ago outlined this at an NSEA talk. And it
Starting point is 01:03:10 was beautiful. And I thought this is the most eloquent way to explain the context about training for hypertrophy. So I'm going to look for three things in your workout. And let's say that you have a particular muscle to grow. Let's say you want your glutes to get larger. Okay. When you're doing your glute exercises, number one, are you feeling the glute contract? Okay. It doesn't have to be there, but that's a good sign if it is. Okay. Let's say I didn't really feel my glute contract. I felt it more in my quads or my back. Okay. Did you feel a big pump afterwards? Now, I didn't really feel a pump there either. It's or during. Okay. Great. Number three. next day, did you feel a little bit of soreness there at all? No, I didn't. Well, that's a very good indication. You didn't feel it during the workout. You felt no sort of pump,
Starting point is 01:03:51 and it didn't get sore. Don't expect much growth. Didn't have... You distributed the work across a bunch of muscle groups. Most likely other muscle groups were too involved, right? Especially if you're like, no, but man, my back got released. Well, that's a really good indication of telling you what the hell was moving. And so in terms of targets, if you were to involved, right? Especially if you're like, no, but man, my back got really st- Well, that's a really good indication of telling you what the hell was moving. And so in terms of targets, if you were to put, I get a 1 to 10 scale, how much should I feel it burning during? Anything less than a 3, okay, it's probably not doing much, right? But it doesn't, like 7 is not, a 10 is not better than 7. You need to feel it, but it doesn't have to be like, oh my gosh, I'm dying here. Soren is same barometer, right?
Starting point is 01:04:29 So if you can get like three, three and three, you're probably in a pretty good spot. Five, five and five is maybe better, but you don't need to go much past that. So I want you to feel the muscle group either working or if you're like, I didn't feel it much, I need really to pump it the next day, it got really sore. Then you're still, you're't feel it much, I didn't really get a pump of the next day, it got really sore, then you're still, you're going on a good path. Again, really sore is in like, ooh, a little tender, but next day it's okay,
Starting point is 01:04:51 they have to add, I could train, no problem. That's really what you wanna go after. And in terms of understanding, is this likely to produce some growth or not? Excellent, excellent, very clear parameters and recommendations I know are benefiting me and will benefit a lot of people. If you'd be willing to throw out a few sort of sets and rep parameters that could act as broad guidelines for people who want to explore further. I
Starting point is 01:05:19 realize that with all these modifiable variables that there's no one size fits all for strength. I love this five to 30 for hypertrophy That's the bottle thing. I don't think I've ever done a 30 reps set of anything But but now that you've thrown that out there, I see it as a bit of a challenge. You want to know it's awesome about 30 You're gonna get an insane pump. You're gonna burn like crazy, but you won't get super sore Because I'm kind of attention to the look so low. It's so light So you can you can get away with those things things and it's hard because your mind is gonna wander. You're gonna get it like rep 20,
Starting point is 01:05:48 you're gonna be like, I'm done and you're like, no, there's a lot left here to get the 30, where like a set of 10 is much easier. Like you're just like, okay, two more, two more. Set of 30 is like, I got 16 more. It's awful, but you're not gonna- Just accounting is worth. It's terrible, right?
Starting point is 01:06:01 And people tend to just kind of like check out. So 30 is possible, but a little bit extreme. But I would recommend them all of them. Like it's a really fun play. You can do different in the same workout too, by the way. Like you could do one set of 10 pushups and then take a little break and then do a set of 25. Like you can mix and match these things.
Starting point is 01:06:19 There's no magic recipe that has to happen for all those or do it different. So Mondays are my sets of 10 days, Wednesdays are my set of 20 days, and Fridays are my set of 30 days, and you can have all kinds of fun there, and it's hard to screw up. Great, I love that phrase is always reassuring. So for strength, is there a sets and reps protocol
Starting point is 01:06:39 that is pretty sure fire? So a way to just think about a really fast answer for power, will speed power and strength is what I just called the three to five concept. All right, so pick three to five exercises. If you're feeling better that day, choose in the higher end. If you're feeling less that day or you have a shorter time frame, the train, go less. So this would be three sets or three exercises exercises or other, or five exercises the most. So three to five exercises,
Starting point is 01:07:08 do three to five reps, three to five sets, take three to five minutes rest in between, and do it three to five times a week. So that can be as little as three sets of three for three exercises, three times a week. That's a 20 minute workout three times a week. It can be as high as five sets of five for five exercises three times a week. That's a 20 minute workout, three times a week. It can be as high as five sets of five for five exercises, five days a week.
Starting point is 01:07:30 So it's very broad and allows people to still stay within the domains of strength and power while still being able to move and contour toward their lifestyle and soreness and time and all those things. The only differentiator to pay attention to between power and strength is intensity. So if you want strength, this is now 85% plus of your max, right?
Starting point is 01:07:52 If you want power, it needs to be a lot lighter because you need to move more towards the velocity and the spectrum because power is strength multiplied by speed. So while getting stronger by definition can help power, you probably want to spend more of your time in the 40% to 70% range like plus or minus. So that's it. Both of them conceptually, they'll work everything else. They exercise the reps the the frequency all that can be still in the three to five range. Just change the intensity depending on which outcome you want. The nervous system obviously plays an important role at the level of nerves controlling the contraction
Starting point is 01:08:27 of muscle fibers. But of course, we have these upper motor neurons, which are the ones that reside in our brain that control the lower motor neurons, the control muscle. And this takes us into the realm of where the mind is at during a particular movement. And to me, this is not an abstract thing. I can imagine doing workouts that are mainly focused on strength or mainly focused on hypertrophy.
Starting point is 01:08:53 And in the case of strength, am I trying to move weights? And when I'm trying to generate hypertrophy, am I trying to quote-unquote challenge muscles? In other words, if I'm just trying to move away from my body, pushing a bench press or an overhead press, I don't know that I want my mind thinking about the contraction of my medial delts. I think I want my mind in getting the way overhead with the best proper form, best excuse me, and proper form. And certainly with hypertrophy training,
Starting point is 01:09:23 best improper form is going to be the target as well. But that simple, or I should say, subtle mental shift changes the patterns of nerve fiber recruitment. So can we say to get stronger focus on moving weights, still with proper form and safely, and to get hypertrophy, focus on challenging muscles, still with proper form and safely, and to get hypertrophy, focus on challenging muscles, still with proper form, and safely. It's very fair. Yeah, as a snapshot answer, it is a very fair thing to think about. Intentionality matters for both.
Starting point is 01:09:57 In other words, if you look at some interesting sciences been done on power development and speed development, the intent to move is actually more important than the actual movement velocity. interesting science has been done on power development and speed development. The intent to move is actually more important than the actual movement velocity. So if you're doing say something for power or strength and you're doing just enough to get the bar up, that will result in less improvements in strength than even if you're moving at the exact same speed but you're intending to move faster. And this is one of the reasons why good coaching matters.
Starting point is 01:10:26 So if you're coaching an athlete through a power workout especially, and they're doing enough to just lift 50% of their winner at max, it's not going to generate as much speed development as them trying to move that bar as fast as I can, even if the net result is the same barbell velocity. Turns out nerves matter. That's it. I mean, I was about to say amazing, but it's a neuroscientist if I say amazing that nerves matter.
Starting point is 01:10:47 What's amazing to me is what, if I understand correctly what you're saying, is that even if the bar is moving at the same speed, same weight, if my internal representation, my thoughts are, I'm trying to move this as fast as possible, versus I'm just trying to get the bar away from me and
Starting point is 01:11:05 get the weight up, I'm going to get different outcomes. Yep, this is quality of work, right? This is, did you do enough to just check off the box or did you actually strive for adaptation, right? Similar concept actually works right peritrophy in terms of there is a handful of very recent studies that have looked at what we'll call the mind muscle connection. And this is doing things like imagine a bicep curl. And you're simply looking at and watching your biceps
Starting point is 01:11:31 and you're thinking about contracting it harder, even though you execute the same repetitions at the same exact intensity. Initial indications are the mind body connection are going to result in more growth than not. You just gave authorization for people to look at their muscles contracting in the gym. Please do. Yeah.
Starting point is 01:11:51 Of course, right? But the selfie is still ruled out. I'd rather you look at your muscles in your phone. So I'm fine with it. Those are initial. We don't have a large depth of research to support that. Maybe some stuff will come encounter it. But it does, it matches what folks in that community
Starting point is 01:12:09 have been saying for a very long time, right? There's actually some stuff on simply flexing in between. So if you've ever seen a bodybuilder, they'll do their set of bicep crittles and then they'll get out in a flex and they'll check. And they're literally, this is what Arnold did, right? This is, if you go back to pumping an iron. Or college weight rooms, I can say.
Starting point is 01:12:24 For some reason, there's something about that age group. Yeah. There's a lot of checking of biceps in college weight rooms for reasons that it's escaped me. If you ever interact with my wife, she will be the first to tell you, I cannot walk past a mirror without like, I'm checking something out. That you can't do the she can't. I can't. Okay. Not her. Me. Like, I'm not gonna cannot walk. All right, well, then I'll be careful not to disparage that. And it has nothing to do with the hypertrophy, but I'm just like, I'm a muscle guy. So I'm always like thinking and tinkering or whatever.
Starting point is 01:12:50 But yeah, it is, I think it's very much worth your time to do a higher quality training session, be more intentional, be present, then just execute in the same exact workout. I think that's globally very clear to be to your advantage. So if you're thinking, like I'm going to, like I don't want to work out today, I got all this going on or I'm tired or whatever, I'm just going to do the work out. I know I can always get through it. Okay. If you can go, you know what, though, like I'm going to cut 15 minutes out of this thing. I'm going to get my head right. I'm going to go get 220 minutes of quality work done.
Starting point is 01:13:24 That's your best option by far. I'm going to get my head right, I'm going to go get 220 minutes of quality work done. That's your best option by far. You alluded to the fact that even just looking at a particular muscle might benefit in terms of the number of fibers you can recruit or it's potential for hypertrophy. I've heard before and I certainly have experienced that muscles that, for whatever reason, genetics or sports that one played, et cetera, muscles that we find that we can contract to the point of almost a slightly painful contraction seem to grow more readily than muscles that we can't recruit very easily.
Starting point is 01:13:59 And the reason I mentioned sports that we played earlier is, you just have to watch the Olympics to see that, you know, swimmers obviously are very good at engaging their lats. Um, you look at the gymnasts, they seem to be very good at engaging everything. Yeah. And they go through a huge number of different dynamic movements. So that explains that. Um, so I find that, you know, if people say, oh, you know, I can't get stronger in this
Starting point is 01:14:21 or my, uh, whatever body part is weak in terms of it and it's inability to engage hypertrophy. Yeah, I see you're gone. That oftentimes that can be because of an inability to engage those upper motor neurons to deliberately isolate those muscles. Are there ways that people can learn to engage particular muscle groups more effectively over time for sake of hypertrophy or strength or for cases of trying to overcome injury potential or injury because imbalance is bad across the board. Yeah, this is actually very common and I think everyone has probably gone to this. There's some part that you just can't get going. For me, that was the lats. That was a rhomboid. So my back muscles. For years, I couldn't activate my lats or my rhomboids. These are the muscle groups that connect your shoulder blades. So if you try to squeeze your shoulder blades together,
Starting point is 01:15:08 that set of muscles there, call your rhomboids. Your lats, of course, are more vertical and pull you kind of up and down. And no matter how many lat pull downs I did, bent rows, pull ups, I could never see any development there. No increase in strength. And it took me probably a decade to figure out how the hell to actually get these things on.
Starting point is 01:15:26 In fact, if you would have asked me, even in my college years, as a college football player, hey, flex your lats, like show me your lats, you would have seen no movement there. When I was doing a pull-up in that particular case, the only way I could get the bar to move was by using my biceps, right? So it's a synergistic muscle.
Starting point is 01:15:44 It was supposed to be a secondary tertiary muscle in that movement, but for me it was primer because of my over strength in my biceps coupled with my lack of activation in the lats. So you're compensating the same movement. Actually, kind of an easy way to think about this is imagine doing a bent row. So imagine you're bent over kind of at a 45 degree or a horizontal angle and you're going to pull a barbell to your belly button. Now, you can actually do that exact same movement with very little back muscle activation
Starting point is 01:16:14 by simply flexing your elbows more. And so you think the barbell is going all the way down, it's coming all the way up to touching my belly and you think you're doing a great back development exercise. And in fact, because of the way that you're executing the movement, you're getting very little back development. This is a really good example of why someone has done a specific exercise many, many, many times, but yet failed to see development in a muscle group.
Starting point is 01:16:36 Which goes back to earlier part of our conversation, which is why exercises themselves do not determine the adaptation. It's the execution that matters. It's the technique, it's the rep range, all of those are going to determine your actual result. So if anytime you were, you're banging your head against the wall and thinking like, why am I not getting movement here, growth or strength or whatever, it's almost one of those, it's guaranteed to be one of those areas, right? You're probably not getting the muscle groups to activate.
Starting point is 01:17:05 In that particular example, just because we're here, try, imagine doing that bent row. Instead of pulling the barbell to your belly, squeeze your shoulder blades together first as far as they can possibly go, and then bring your elbows up without changing the angle of your elbow. So in other words, without bringing your hand closer to your shoulder, so keep that same angle and come up as high as you possibly can and then finish out the movement. That's going to guarantee a utilization first of the back muscles and a finishing with the biceps at the end, which is how that movement is supposed to go. So how do you coach into that? Well, it can be a number of things. Whenever I'm diagnosing movement quality,
Starting point is 01:17:49 I look for a handful of things, but very first one is awareness. You'd be surprised how many folks, when you just simply tell them, that muscle group right there, and maybe you give them a tactical prompt, so you touch it, or you put something against it. This is actually why, sorry, I'm jumping over the place, but this is why things like a belt work very well for actually increasing abdominal strength. So a misconception out there is if you wear like a belt work very well for actually increasing abdominal strength. So a misconception out there is if you wear like a belt when you're lifting, then the belt kind of does all the work for you and your abs get weaker. That can happen, but the exact opposite can happen as well.
Starting point is 01:18:17 So if you take a belt, for example, and you cinch it down really tight, and then you just completely disregard your midsection, you will see a loss of strength in your midsection because now the belt is doing the work. But if you put the belt on just a little bit, kind of tight, to where you get some sensory feedback, and you think about using that belt as a way to activate the core musk mixture, you will actually see a higher, and if we look at it like EMG activation, the core muscles would be activated higher to a greater extent than when the belt is off.
Starting point is 01:18:47 Because of proprioceptive feedback. 100%. And for those that are wondering what proprioceptive feedback is, proprioceptive feedback is that there are nerves that extend out to the muscles that control muscle contractions, but then there are sensory inputs from the skin and muscle that go back into the nervous system and those work in concert and that feedback is proprioceptive. I think it literally translates to a knowledge of where one's limbs are and what's happening on those limbs.
Starting point is 01:19:12 In space, yeah. I've seen, I don't have a training partner, but I've seen in gyms where someone will be training and someone will tap the muscle of the person who's doing the work in order with, this is consensual tapping of other people's muscles, not walking around to be touching people's muscles, please. That to provide that proprioceptive feedback so that the person doing the exercises,
Starting point is 01:19:36 it becomes more aware of the muscle that they're supposed to be training. And it seems that that's probably an effective practice. Yeah, I'll give you two examples. I'll go to the back with that pulling movement, and then I'll stay in the belt really quickly. So a very easy example that you can do right now, listening, and I'd learn this from Brian McKenzie
Starting point is 01:19:52 or Mutual Friend, right? So if you take your hands and open them up, like you make an L with both your hands, and now take those and put them around your waist just above your hip bones. Now, what I want you to do is press out as hard as you can on your hands with your core. And you can feel a lot of core activation.
Starting point is 01:20:09 And most people think core activation is the front of your stomach, right? Your six back. What you need to do is create a cylinder around your back. So it's the front, it's the side, and it's the back. So if you take your two fingers, point them. Now put them just outside your belly button. Can you move your fingers
Starting point is 01:20:27 by just moving your ab muscles? 90% of people can sit do yes. Same exact thing. Now go to that same position just above what's called your ASIS. So your anterior superior elix Right in the front, can you now move? Great, 50% of people are not going to get any movement there. Really?
Starting point is 01:20:50 Take your thumb and go right above your PSIS. My what? PSIS, posterior, superior, that's fine. Right. Now, can you move? Most likely no. Sort of if I do a mini, low back extension. Don't just with your core musculature. Barely. Yeah. low back extension. Don't. Just with your core musketeer. Barely. Yeah.
Starting point is 01:21:08 Maybe 90% of people can't. If you can't perform that contraction, you can't stabilize your spine. So only way to get stabilization in your spine is then to go through hyper extension. And now that's a compression strategy you're putting on your spine, it's better than rounding your back, like going forward, but overextension is not great either. So you want to be able to flex the muskature in a cylindrical fashion, so you have control. So if you go back to our very first things and with your hands open, and you put them right here, and if you're like, I can't get activation, if you pay attention to your thumb, right? Now just move your thumb.
Starting point is 01:21:42 And now you see activation back there, right? Mm-hmm. Boom. Now if you can imagine back there, right? Mm-hmm. Boom. Now if you can imagine turning that on just a little bit, and now notice how I can do this by the way, at the same time I'm talking. If you have to go, we don't have control, right? So you have to be able to separate breath from brace.
Starting point is 01:22:00 So now if I can put my position, self in a position, and Kelly started it, has always said 20%. He'll be 20% activation here. And now I can squat, I can hinge, I can put my position and Kelly started out, has always said 20%. He'll be 20% activation here. And now I can squat, I can hinge, I can jump. I don't need to be locked down to 100% scream to be able to brace my spine. That's gonna be ineffective and wasteful.
Starting point is 01:22:16 I wanna be here. Well, the belt provides that proprioceptive feedback where I can put it on 20%. And it just is a reminder, if I don't press against the belt the belt slides and falls down a little bit because it's not on super tight. If it's on so dang tight it's doing the work and I forget. So we just want a little bit of feedback there. Same thing with your upper back if you're having a difficult time activating those rhombuses of those lats. So I'm going to do a
Starting point is 01:22:40 simple thing where they take their finger, put a right between your shoulder blades and you just tell them things like hey squeeze my finger, squeeze my finger. As you're doing your bent row or your pull down, you can touch the lat. You can do just visualization stuff. So just imagine like a 3D rendering of that muscle group and you're watching that muscle group contract is very powerful and very effective to do it. So a touch, a visual, all this stuff can help get people to activate. Outside of simple awareness, typically eccentric overload is a very effective way for activation
Starting point is 01:23:14 of a difficult to target muscle. So the lowering of the bar or the lowering of the weight? The movement of the weight away from the body is not necessarily what is lowering because that kind of depends on what I'm doing, right? Right. Things like a pull-up. If I'm going to do a pull-up and I have poor lead activation, I can still get the pull-up muscle movement executed by contraction of the biceps and things like that. However, to make the movement simpler, I'm going to go all the way to the top.
Starting point is 01:23:41 So imagine stepping on a box or something, going all the way to that top of that pull-up position. And starting from there, I want you to simply lower it under control. And so you're just simply breaking the movement down into smaller pieces that allow you to focus on the execution more. It's going to be great. East Centralx are great for strength development,
Starting point is 01:23:58 very good for hypertrophy, and allow you to focus on control. I'm willing to bet a huge percentage of you out there who've like, I've never had a sore lat. You know, I've done a lot of pull ups and things like that. If you do that eccentric only, you'll probably wake up the next day going, oh gosh, I feel it there.
Starting point is 01:24:14 And that's a sign even if you didn't fill it in the workout, but I got a little sore the next day. Keep down that path. And then eventually you'll be able to do a concentric, maybe take a break, maybe do an isometric where you just hold that position, and eventually work that into a progression where you can do the concentric, eccentric, and isometric portions, and get activation. So that may take you six weeks, may take you six months, but that's generally a pretty
Starting point is 01:24:39 good strategy for learning how to activate a muscle group. Terrific suggestions. Is it true that eccentric emphasized movements might require a little bit longer recovery or they lead to more soreness than eccentric movements? Yeah, they typically can, but they're also higher force output. So very good for strength development,
Starting point is 01:24:57 but they're going to lead on average to more soreness. So more potential for intercellular disruption that is gonna be associated with pain. There's not as much, people will like to explain muscle soreness as a result of micro trauma and micro tears in the muscle. That can happen, but that's not the norm. Most of the time, it is things like disruption of calcium that's going to lead to excessive swelling, excessive pressure, and that's going to be then translated as extreme pain.
Starting point is 01:25:23 So that's probably explaining more muscle soreness than actually micro trauma. Terrific. I was going to get to breathing later, but maybe just for now, if we can do a brief little foray into breathing, as it relates to weight training, is there a prescriptive for how to breathe during resistance training? Here I'm thinking with weights, not necessarily body weight only movements, although I suppose it could be that applies 75% of the time to 75% of people. What I was taught, and I'm hoping you're going to tell me this was wrong, because then there
Starting point is 01:25:58 might be more benefits that awaiting me, is that I should exhale on the effort and inhale on the lesser effort portion of an exercise. Is that true? Is there a better way to breathe? There is a better way to think about it. So number one, if you can breathe and brace, then this conversation goes away. So if you can maintain intramuscular, intradominable pressure while breathing, then I don't really care
Starting point is 01:26:30 when you breathe. Very challenging to do at very heavy weights. If we flag this on two areas of a paradigm, paradigm one over here you're going to do a set of 30. And you're going to do front squats where a barbell is sitting on your throat. If you don't take a breath, this is going to end one way and one way only, you passing out. Clearly has to be some breathing strategy. The other end of the spectrum is,
Starting point is 01:26:54 let's say you're gonna do a vertical jump. You don't need any amount of breath there, it's never gonna happen, right? The question is, what about in the middle? Right, so I'm doing some sort of strength training there. Well, number one, make sure you're braced and then you can get away with less need to worry about it. In general, a decent strategy is to maintain a breath hold during the lowering or eccentric
Starting point is 01:27:18 or most dangerous part of the movement and then you can exhale on the concentric portion. So if the bench presses our example, if you held in, braced, lowered it into control, and now started the concentric pushing away for it, and then you wanted to take an expiration. Pfff. During the last half the concentric portion, that's an okay strategy. If you're going to do a single rep,
Starting point is 01:27:39 you don't need to worry about it. You can just avoid or omit breathing entirely. You're gonna be just fine. If you're doing more than that, especially three to four to five to seven eight, you're gonna have to omit breathing entirely. You're gonna be just fine. If you're doing more than that, especially three to four to five to seven eight, you're gonna have to have some breathing strategy. A very common one is probably every third breath. I'm gonna do like,
Starting point is 01:27:58 exhale, the third, reset, re-breathe, something like that. If you feel like you need to breathe after every one, that's okay, but it's gonna get wasteful because you have to take time in between reps of sitting there. If it's a squat, that's different versus a deadlift if you're resting at the bottom. So there is a little bit of game here. So in general, though, is that 75, 75 kind of really thrown out, you threw out. Breathe in, do the lowering and exhale on the out. If you have to, less reps, don't worry about it.
Starting point is 01:28:25 More reps, then you need to come up with some sort of breathing strategy. How about breathing in between sets and maybe even after the workout? Yeah. This is something I think a lot of people overlook. And because it is the case that recovery has to do both with the specific activation and to muscles and the nervous system,
Starting point is 01:28:46 but also the attacks on the nervous system can also take place between sets. I mean, if you're really geared up between sets and you go to adrenaline, you know, as high in between sets or close to it as you are during your sets, you can imagine that the recovery would take longer, or at least that you're not spending adrenaline in the most efficient way if there is such a thing. Yeah, fair. You're not going adrenaline in the most efficient way if there is such a thing. Yeah, fair. You're not going to see any athlete that I work with, just breathe in between. Whether it's in between innings or in between rounds, every single one of them is going to go back, sit in the stool, and they're going to
Starting point is 01:29:17 immediately be into a breathing routine. A very intentional one. They're a little bit different from every athlete, depending on the sport. Even PGA golfer, there's going to be a, we just hit our ball. We're moving to the next one. We're going to go in a breathing strategy. Everyone will miss. It's a huge area of potential benefit and consequence if you're just ignoring it. In general, we want to do any sort of calming breath. We want to restore. It depends on if the, it depends on what combating, or combating a little oxygen or high CO2. So that strategy is going to be a little bit different. But in general, that is a huge time opportunity to get better. In fact, people can go back and listen to some of your earlier episodes, or you talked about what you have spoken about,
Starting point is 01:30:01 I think, on this show, when neuroplasticity works, and if you're losing that opportunity, post-exercise, you're leaving gains on the table, if you will. So, not only are you going to see everything athletes that I work with mostly have a brazen strategy in competition, we're not going to just finish a workout high five drink water and walk out of the gym. There will be a down-regulation strategy that is heavily involved with some sort of light control, as well as breath control.
Starting point is 01:30:29 The individual prescription on that, there's a ton of variation with what you can do. The easiest thing is do something that calms you down. Most likely that's going to be moved towards as much nails or breathing as you can possibly do. And a really easy rule of thumb is a double exhale length relative to inhale. So if you need to take a like four second inhale, double that time and breathe out for eight seconds.
Starting point is 01:30:53 A box breathing is fine, so equal inhale, equal hold, equal exhale, equal hold. So four second inhale for second exhale, hold, et cetera, et cetera. A triangle is fine too. There's a lot of ways. You can get really complicated, like what Brian McKenzie will do in Rob. And those guys have, you can get all kinds of systems
Starting point is 01:31:11 for inhale, exhale, control, and can be optimized. But some strategy of calm, we're gonna almost always put you on your back or close, and then we're gonna cover light. We can do some, like we've done actually a number of musical interventions as well, but you can as simple as sit down a locker room if you have to, and just breathe for five minutes.
Starting point is 01:31:36 That alone is gonna be productive. That's great. If you're breathing in the locker room for five minutes, I suggest closing your eyes or you get some funny looks, and if you'll still get funny looks, but you won't see people looking at it. Yeah, exactly. I love this.
Starting point is 01:31:48 And I started doing this because you and Brian McKenzie informed me about this. And it completely changed the rate of recovery for me. I realized that I was leaving workouts, both endurance workouts and strength hypertrophy workouts, feeling great, but looking at my phone, getting right into email and meetings, not concentrating on my breathing. And all I did was to introduce a, on your recommendation, a five minute down regulation.
Starting point is 01:32:13 So exhale, emphasize breathing, a bunch of different varieties, physiological size, box breathing, exhale, emphasize twice as long as the inhale component for five minutes. And I noticed two things. One, I recovered more quickly, workout to workout. No question about it. Yeah. The numbers told me that. And the other is that I used to have this dip in energy that would occur three or four hours after a hard workout. And I always thought that had to do with the fact that I generally eat the meal at some point post workout. Turns out it wasn't the meal at all. Yeah.
Starting point is 01:32:45 It's that that adrenaline ramp up during the workouts. I wasn't clamping that at the end. And so I think eventually it's like crashed. And then three or four hours later, I'm having a hard time even reading what's on the screen of my computer thinking maybe it's the screen. Maybe it was what eight full lunch turns out the down regulations allowed me to work through the afternoon with no issues whatsoever.
Starting point is 01:33:07 It's really been quite powerful, and so I'm grateful to you for that, and I think this is something that I think 98% of people are not doing, and it's only five minutes. You do even have to do five. Give me three. If you really have to push it, give me three, and you can even do this, you can save time. You can do this in the shower if you have to. So you're done, you're finished, drink a water, whatever it has to be, and you're getting in a shower, you're getting ready, just giving three minutes in the shower. It's not ideal, but as little as that, it can pay huge dividends. You need some sort
Starting point is 01:33:38 of internal signal that we're safe. Like throttle down here, we're going to move on. That has to happen. I could go on and on here, but I think we're making the same point kind of an over again. It's big deal and do it. Yeah, and you're saving energy. I mean, the energy here is neural energy. I think fighters do this. Good fighters learn to do this between rounds.
Starting point is 01:33:58 Sprinters learn to do this between events. I think humans should learn how to do this between any, you know, sort of interval type activity, including work, social engagement. I mean, this is such a powerful tool. Do this for one minute after every important, whether it's an individual high-volatile interaction or if it's a, you just did a nice 45-minute sprint to work and you're deep into it or whatever fine. Just give me one minute. Set your alarm just one minute and that also will pay dividends. I love it. And as I said, it's made to eat
Starting point is 01:34:31 outsize a different positive difference on my training, but also activities outside my training. Which is for me, I'm not a professional athlete. I train for health and because I enjoy it, but when a really hard workout starts to interfere with the ability to do the other things in life, that's not a good situation. So this is really terrific. There's a lot more in each of those categories of strength and hypertrophy, but you've given us a tremendous amount of valuable information there.
Starting point is 01:34:57 Maybe now would be a good time to shift to endurance. And of the four types of endurance, and maybe you could remind us what those are, what do you think are the two that most people are seeking or pursuing in terms of health and aesthetics? Right? I mean, realize that we probably have athletes out there as well, but I think when I think health and aesthetics, I think, okay, the ability to do sustained endurance, 30 plus minutes of some ongoing activity. How does one maximize that work? What are the modifiable variables?
Starting point is 01:35:30 And then maybe you could tell us what the other major category is that people ought to have in their kit. Okay. So starting off with exercise choice. One thing, as soon as we cross into the endurance world, and this is true for all four of those categories, exercise choice needs to be very concerned with eccentric landing. So you don't need to avoid it, but you need to recognize it relative or compare it against those other strength and speed ones.
Starting point is 01:35:58 The volume is low on those ones, so if you have some eccentric absorption, it's okay. But as we sort of talked about five minutes ago, more eccentric means greater chance of muscle damage, so on us. So if you take something and magnify it across 30 minutes, or even five minutes, but of maximum exertion, you have a recipe for blowing up. You can imagine I haven't run in forever, and I've just listened to this human lab podcast and I'm, okay, I'm going to get into my zone to training, whatever it is, whatever. And I start jogging, I'm gonna do,
Starting point is 01:36:27 I remember when I used to be able to do 25 and you just do a 25 minute jog. The amount of eccentric landing that just occurred on every single step because you're never with running, even slow running, you never have two feet on the ground at the same time. So it is a one foot land, one foot land,
Starting point is 01:36:42 your entire body mass plus gravity onto one leg at a time, repeated now hundreds of times. That eccentric landing is going to cause tremendous soreness. Your quads are going to go, you're probably going to get shin splints, which is what those are entirely caused by eccentric landing. And when the tissue is not ready to tolerate that, if you're not landing correctly, this is when knee pain happens, back pain, shoulder neck pain, because of movement compensation. So anytime we start pressing to fatigue, let's be very concerned with there.
Starting point is 01:37:13 So my initial recommendation is, start with activities exercise choice wise that are mostly concentric based. So think about a cycle. So when you're riding on a bike, you're pushing the pedal, but you're never landing and absorbing it. So you could go out and do a 45 minute bike ride, and you're not gonna get that sore
Starting point is 01:37:30 because there's not a lot of eccentric load. Swimming, similar thing here, right? There's some eccentric when you can, it's the water, but fairly minimal. It's mostly a push, push, push, push, push, no load. Rowing, similar thing, mostly concentric, pushing a sled is fantastic, going uphill, running or even walking hard uphill, all good because they're very minimal landing relative to like running downhill, which would be a very, very bad idea to start.
Starting point is 01:37:59 So if you're first jumping into these things, progress your volume for endurance, very slowly, if it involves eccentric landing. A really bad strategy, we'd be to jump in and do, say, circuit training class that involves a bunch of box jumps. Right? This is not a good way to do your first four-way into conditioning. You're going to get incredibly sore because you're jumping in the landing. You're now looking at three to 10X body weight
Starting point is 01:38:29 in terms of absorption with a single land, even if you're just jumping. So be careful of that in any of those endurance areas of exercise choice. So what to pick? Pick the one that you are most technically proficient because you're gonna do it a lot. It's gonna be a lot of repetitions. Whatever one you feel the most joy in, if that's rowing, great, if that you are most technically proficient in, because you're going to do it a lot. There's going to be a lot of repetitions.
Starting point is 01:38:45 Whatever one you feel the most joy in, if that's rowing, great, if that's pushing a sled, it doesn't really matter. You can do this actually with weights. This is our preferred way, by the way, with our athletes. So we might do a 30-minute circuit where we do a five-minute farmer's carry. With a pretty light weight, so you're just going to carry some weights in your hand, and you're just going to walk up and down the street for five minutes. You're gonna set that down and then you're gonna do, say, a three minute plank.
Starting point is 01:39:09 And then you're gonna pick that up and you're gonna do body weight squats, like slowly and just tempo. And you're gonna do a handful of different exercises so the athletes don't get super bored. Or a very simple one if a 30 minute workout, 10 minutes on a treadmill, 10 minutes on a bike, 10 minutes on a row.
Starting point is 01:39:24 But for those of you that are like, oh my God, I can't do 30 straight minutes of running. Cool, break it up into three or four different exercises that are all fairly safe. So that's how I would do that long duration piece for exercise choice. And then in terms of heart rate during that period, I mean, how much tension should we pay to this?
Starting point is 01:39:40 They're kind of very broad, prescriptive, I've thrown out on this podcast a few times based on my read of the literature. It is for most people that are oriented toward health, including people that are working on size and strength gains, hypertrophy and strength, of course, that getting 150 to 180 minutes of so-called zone two cardio, you know, can just have a, just barely have a conversation, but if one were to push any harder, you wouldn't be able to do that kind of thing. It's just a generic recommendation that almost everybody should follow
Starting point is 01:40:09 in order to just keep their cardiovascular system healthy. But I know there's a lot of nuance there, and some people would like to be able to run continuously for an hour at speed, right? Yeah. Obviously not sprinting, but what are some of the finer points on long distance endurance? So I have to often should one do it.
Starting point is 01:40:28 Okay, frequency you could do it as daily. Even when strength doing strength and hypergrapory. No question. Well, I think it's an important point for people to hear it, because a lot of people think that they are going to greatly diminish their strength and hypergrapory. Yeah. Games as it's often called by doing in zone two cardio. Zone two, you have almost no ability
Starting point is 01:40:47 to block your hypertrophy. Zone two, truly within that category, if you're talking about conversational pace, there is very, in fact, there's strong reason to think that is not gonna influence hypertrophy for the overwhelming majority of people. It might even help it by increasing blood flow to the various levels.
Starting point is 01:41:03 Absolutely. Does it matter, let's say someone's doing primarily strength and hypertrophy, majority of people. It might even help it by increasing blood flow to the various. Absolutely. Does it matter? Let's say someone's doing primarily strength and hypertrophy. Their primary goals are strength and hypertrophy. And then they're going to do, they're going to hit that 150 to 180 minutes zone to cardio per week, assuming they're breaking that up into three or four sessions. Does it matter if they do it in the same workout before or after? Does that matter? I tend to do just by way of example for people, certainly I'm just one example. I tend to do resistance training one day, then I'll do zone two cardio the next day I jog because that's the thing I prefer. Then I'll do strength
Starting point is 01:41:36 hypertrophy training the next day and then jog for my zone two cardio and then I take one full day off a week. I've never actually done the zone two cardio on the same day, but were I to do it on the same day? Would it matter if I did it before after my strength or perjury training? Not really. Okay. You're gonna be just fine. Interference effects, the interference effect
Starting point is 01:41:54 is what this is called. So this is all the way back to 1980, Bob Hickman's stuff, right? And he was actually working in a lab with John Halazi who's one of the fathers of exercise bowel chemistry. And the story goes that Hickman came in, he was a strength training guy, and Halazi and almost all those initial exercise physiologists were conditioning folks, right? So it's almost always swimmers and runners. And that's why a bulk of the exercise physiology historically is shaped in that direction. That's one of those scientists we're interested in.
Starting point is 01:42:25 So Hickman was there in the lab and then how much of this is myth or not over the nose, but so the story goes. This is sort of chipping back and forth, and you know how from a PI to a postdoc, and kind of that rousing works a little bit. And eventually, he's like, you got to start running with us, and he's like, you got to start lifting with me and kind of goes back and forth. Well, you know who wins in that equation. It's not the postdoc, right? So it's the PI gets in, it's, it's okay, fine.
Starting point is 01:42:51 So he starts running with Elazi and then eventually starts to realize I'm getting weak. I'm losing strength and I just can't, I think it was his bench press specifically was going down or maybe his squat. I can't remember who knows if it's even real, but point is. So he's going along and so eventually that starts to create a little bit of animosity. And it's like, actually, I don't think this is good for me and then blah, blah, blah.
Starting point is 01:43:10 And so they did what any good scientists would do and said, well, let's find out, right? And so they he run a really famous experiment where he took a group, three groups. One group did an endurance piece, right, the steady state cardio. One group did a strength training piece. And then the third group did both of those workouts combined, not like a reduction, so both volumes stacked on top of each other.
Starting point is 01:43:32 And the results are fairly predictable. In terms of the endurance group only had the greatest increases in VO2 max on endurance markers. The strength training group had the greatest increases in muscle hypertrophy. But where the interesting part was where this whole field started was the combined group. So this is concurrent training is what it's generally called. So you're doing concurrent things. And typically that means hypertrophy and strength stack that top of some steady state endurance
Starting point is 01:43:56 in the same. Same same work out or same like week. It doesn't really. It can be kind of all these. Well, the concurrent group saw the same improvements in VO2 max as the endurance group. And he's like, well, okay, so the strength training did not compromise the endurance adaptations. However, they saw much lower increases in strength than hypertrophy. lower increases in strength than hypertrophy. And so it was the conclusion was the addition of endurance work compromised muscle growth
Starting point is 01:44:30 and strength development. However, the addition of strength training to your endurance work will not compromise your endurance gains. Now, that second piece has been shown countless more times, right? So if you're an endurance athlete, adding strength training is almost always
Starting point is 01:44:44 going to be massively beneficial. Very little chance of judgment. times. So if you're an endurance athlete, adding strength training is almost always going to be massively beneficial. Very little chance of judgment. So I agree endurance athlete is going to have some sort of strength and power component of their training. The controversy though came in the interference effect. So how much endurance training really blocks muscular development? And for years, myself included was we preached hard. You know, don't do these two things at the same time. My friend, my colleague, Kevin Mirac, has a really nice review article, Jimmy Bagley,
Starting point is 01:45:10 those two guys put this thing out. You can go read that where they cover all these things and they've got some nice figures in there. But the general answer here is interference effect is sort of real, but it's probably greatly overblown. It matters. So are you talking about a 20-minute jog at conversation pace?
Starting point is 01:45:27 That's probably doing very little. With the assumption that, are you doing an eccentric based exercise, like running? Well, then you're gonna have more of interference effect than cycling. That makes a ton of sense if you think about it, right? What's your total energy intake? If you're eating sufficient calories,
Starting point is 01:45:43 you can still be in an animal X-Tate. If the addition of extra energy expenditure, solid really is, Mark, the cardio, put you in a negative energy state, it's gonna become very difficult to go through animalism. So those things matter. If you're talking about doing like running a few laps around the track as a warmup,
Starting point is 01:46:03 like that's not interference effect. What we're really talking about is a big volume performed consistently. Now, after Hickman came out with this paper in 1980, people followed it up in the 90s and 2000s with mechanism. And we started to look and see, and we started to see, hey, there's this cell-singling pathway that goes down to called M-tore,
Starting point is 01:46:22 and that's what leads to muscle growth. And then on the other side of that equation, there's a thing called AMPK, which is more cell signaling pathway that goes down to called MTOR, and that's what leads to muscle growth. And then on the other side of that equation, there's a thing called AMPK, which is more associated with mitochondrial biogenesis and endurance. And there's this little molecule in between, at the time most people would point to TSC2.
Starting point is 01:46:37 Well, turns out AMPK activation is fine. If you activate MTOR, there's no bearing on AMPK, but if you activate AMPK, it's gonna activate TSC2, which you activate MTOR, there's no bearing on MPK, but if you activate the MPK, it's going to activate TSC2, which inhibits MTOR. And so it was like, we had practical outcome. I eat Hickman, you're going to get weaker. Now we had mechanism. So that story became very, very strong that this interference effect. And this is how science should work, right? When you see mechanism match up with practical human outcome, it's a strong. It was still wrong. It just took more science, right? And this is why we always have to give science a bit of time. And you have to be willing to follow, right? And
Starting point is 01:47:17 again, even me in the field who has a practitioner background and science, I felt very strongly, this is a big problem. It just didn't turn out to be the case. And enough studies came out where I'm like, okay, it's probably not that big a deal. Unless the movement is heavily eccentric-based, the volume is very high. You're trying to maximize muscle growth and energy's not controlled.
Starting point is 01:47:40 If that's not all the case, interference effect is probably not something most people should worry about. When you compare that against the well-roundedness that you need for total physiological health, probably not a big deal. Very reassuring from me here, because I do enjoy lifting weights and I really enjoy running and I love running outside.
Starting point is 01:48:02 I believe I used to experience the interference effect when I used to do a very long run on Sundays. I would just go out for, you know, two hours or something like that. I don't know that I ate enough or who knows. I always feel like I eat enough or more. I love to eat. But that long Sunday run always made it hard for me to make progressive gains in strength and hypertrophy in the gym. Whereas when I cut that to 30 minutes, three or four times a week, I don't see any interference effect at all. Probably very real. And I haven't trained specifically for endurance in a very long time. So I don't, I haven't experienced the non-interference effect, which as you said before, most, if not all endurance athletes probably are, or at least should be doing some sort of strength work, just to keep the undercarriage strong as
Starting point is 01:48:48 I think that's crazy. Yeah, there's a bunch of reasons. Yeah, but yeah. So, what are some protocols that people could explore for continuous endurance training? I mean, I've thrown out this 150 to 180-minute zone to cardio, but that's really the kind of kindergarten of endurance. And there I'm probably being generous, it's probably the nursery school of endurance that everyone should do. What sorts of other protocols? I realize that can be very
Starting point is 01:49:11 goal-directed, but is it unreasonable, for instance, for somebody to do four hours of continuous endurance training with intervals in there as well to get it kind of all around heart health and the ability to go long distances. Yeah, I'll answer this too. It's the very first one. The tackle of the the long duration endurance is how I refer to it. You asked really about heart rate zones. To me, that's almost totally irrelevant. It doesn't matter, right? If you're moving, you're moving, that's that's the functional piece here. If you want to push it and go at a non-conversational pace, that has tremendous health benefits. If you want to do it a little bit slower, fine. If you're at the pace where you can
Starting point is 01:49:50 have a conversation, to me, I don't even count that as exercise. That's not a pejorative, by the way. That is just general physical movement. And it is extraordinarily clear. You need a lot of that. You need a lot more of that than we get. You can do this in a couple of efficient ways, just taking your phone calls moving. If you've got a 30 minute call every day, or most days the week and you can do that while moving, you've checked not that whole box, but a pretty good chunk of it.
Starting point is 01:50:16 And that could even be done inside. 100% pacing back and forth. I'm a big pacer. The, yeah, me too. Like you probably saw me, like I'm gonna walk up and down all over the place. Most of the time when I'm in my officeacer. Yeah, you meet too. You probably saw me. I'm going to walk up and down all over the place. Most of the time when I'm in my office working, I come. I'm shadow boxing.
Starting point is 01:50:29 I come to an air squat. Not even intentionally. I'm just like, do you have one of those treadmills under the desk? I don't, but like every lab I ever came through somebody did. We did an episode on Workspace Optimization. And the data on those treadmills are pretty interesting. They definitely increase alertness, which for obvious reasons, that even a little bit of movement
Starting point is 01:50:46 is gonna generate a little bit of adrenaline. So pacing around moving, taking calls, moving, getting walks when you can, and then in terms of building endurance, let's say somebody wants to quote, unquote, get into better shape. Yep. They already, may or may not already have some size
Starting point is 01:51:03 and strength that they're happy with. And they just want to get in, they want to improve their health. Yep. So I can, does that 150, 180 meant thing tick over into a different protocol? Yeah. Okay. So I think the way that I can outline a weekly schedule, just as a conceptual model here. That long duration stuff is not even counting as I mentioned, right?
Starting point is 01:51:23 It's just a, this is what you need to do as a human moving forward. We haven't improved. If you're extremely unfit, you may see some changes in cardiovascular health. But for the most part, this is just knocking out the general physical practice you need to be higher functioning. So whatever that time domain is, I don't really care. It's not a huge concern of mine. What I think you need to hit are these nodes. You need to do something once a week that gets you to a maximum heart rate. Now, I don't have to literally mean max, but close. This means really sucking for error. Really?
Starting point is 01:51:53 Like as high as you can possibly get, you can wear a heart rate monitor if you want. But maximum heart rate, the rough equation we say is 220 minus your age. So if you're 40 years old, your maximum heart rate is probably about 180 beats per minute. Now I can tell you flat out right now. My max heart rate is close to 210, which means I'm 10 years old. So take that number with a grain of salt. I have had a bunch of professional athletes who are in their 20s and their max heart rate is 175.
Starting point is 01:52:21 And they are way better shaped than I am. So maximum heart rate is not a good proxy for physical fitness. It's a rough number. An easy way to do it is if you have a heart rate monitor or anything like that, do the hardest workout you can possibly do, see what the highest number you get as and soon that's close. That's if you want to just start at 220 minus to age, that's fine too. Do something though where you're like, yep, this is death. This is really, really challenging.
Starting point is 01:52:45 How long? However long that takes you. That can be a 30 second go on an aerodine or aerosol bike. That could be a, do one of those things where you kinda like sprint, run as hard as you can during the straightaway on a track and then walk the corners. Kind of an old classic back when I knew
Starting point is 01:53:03 an Iber kid's interval training. They don't do that anymore. I guess I don't know how I would've talked about it. In P class, we had to change. And if you didn't bring running shoes, you had to do it barefoot. Oh, I love it. And I love your teacher.
Starting point is 01:53:14 Yeah, it wasn't a, we were our football, basketball, baseball, teams weren't that good, but anything like running across country just goes to where I grew up. The brutal, brutal coaches, so that yeah, they'd make the, all kids do these runs. Yeah, so it can be in the 30, probably seconds at a minimum. It's hard to get you to a true heart rate max in shorter than 30 seconds.
Starting point is 01:53:35 You can get the total suck in under 20 seconds, but getting to a true heart rate max is probably gonna take more than 30 seconds. So it doesn't really matter what you wanna do. It can be again, a sprint uphill. It could be what you're talking. It could be burpees to death. You know, like whatever whatever you want to do, just those have any centric component, right? Yeah, they do. Yeah. No question about it. But if you did, if you just did, I'm going to do as many burpees as I can for 90 seconds, it probably won't take you much longer than that to get to close to it.
Starting point is 01:54:06 And his acts will work out. Could be. So once a week, get to max heart rate. Touch it. I love it. Touch it. It's not the best, but it'll work. And what are the specific benefits that that provides?
Starting point is 01:54:18 Okay, so earlier in our chat, we outlined the real specificity, specific adaptation to a post-man. If you're never getting to that high of a pace, it would be like trying to get stronger, but only going to 60%. So every cardiovascular adaptation that occurs with cardiovascular training is simply going to get to the top or end by doing this. So if you just start at the heart itself, stroke volume increase. So this is a amount of blood that's kicked out per contraction, cardiac output, resting heart rate. If you go to the endothelial function,
Starting point is 01:54:50 you're talking about nitric oxide release, endothelial health in general, capillary, mitochondria all the way down. Like you just walk through the whole system, pulmonary exchange to the lungs, all of those are going to benefit by being challenged to their maximum. You also teach you where your vomit reflexes. Yeah, there we go.
Starting point is 01:55:08 Right? Let's hope no. Stress is what causes adaptation, right? So if you push your, okay, here's the difference. If you did 25 minutes of steady state, you're not challenging the same thing as what we just talked about. The way that I explain this is if you understand the point, the point of physiological failure, then you understand the place of adaptation. That's it. So if you and I both go run on,
Starting point is 01:55:31 we did a both did a VO2 max test. So a classic VO2 max test is going to take eight to 12 minutes, and it's going to look something like this. We're going to get in a treadmill, and we're going to run, and every minute I'm going to just slightly increase that treadmill, either the speed or the grade, most of the time it's the speed, right? So we get to a high grade, say 10% grade or something, and then we go five hours per hour, 5.2, 5.4, and we just go until you can't go any longer. Now let's say you and I did that
Starting point is 01:56:00 and we had the same exact time frame, and so we both went eight minutes. The time that you last is not the thing that we care about, right? It's the volume of oxygen that you breathe out is what determines it. So let's say we went with the same time domain and we had the same VO2 max. Let's say they were both 50 milliliters per kilogram per minute, which is like a okay number, but that's nothing to be extremely proud about. Just because we have the same number does not mean we have the same point of physiological
Starting point is 01:56:26 failure. And this matters because it's going to answer the, what do I do about it then? Question, right? So, if you got off and I started asking you a series of questions and you're like, and I basically said, why'd you quit? You know, why did you jump off the treadmill? Why'd you stop? And you were like, my chest, like I couldn't catch my breath.
Starting point is 01:56:42 I thought my heart was going to explode. Okay, great. If you ask me and I said, my legs were on fire, like, I was breathing hard, but I couldn't take another step. This is a very rough indicator of different places of physiological disruption. Now, what I've seen a lot with my professional athletes,
Starting point is 01:57:00 especially like fighters, they are going to generally fail in their legs because they don't often do a lot of strength training in their legs. They don't do a lot of leg work. They're going to generally fail in their legs because they don't often do a lot of strength training in their legs. They don't do a lot of legwork. They're fighting on their back literally a lot or on top or on their knees. So their legs tend to give out before there. If someone who feels in the cardiovascular system, like so you did a lot of leg training, typically I can endurance out there, who's that's not going to be their issue. It's just going to be they're going to reach a heart rate and ventilation threshold that's
Starting point is 01:57:26 they can no longer handle. If I put you on the exact same training protocols, it's not going to be as effective because you're going to always fail at your legs and they're going to always fail at their cardiovascular system. I need to flip that, right? You need to put you in a position to where you can reach a true heart rate or ventilation challenge while your legs are still hanging in there or the opposite. So the training protocol is based on that point of
Starting point is 01:57:52 failure. The adaptation is in the same thing. So if you are failing because of your legs, then you might see a greater increase in capitalization in your legs relative to somebody else who's failing in their cardiovascular system, they may see a greater change in something on that side of the equation. So that it matters how you're failing at all times. What I love about this is that it sounds like it's like a thermometer for where one is weak and needs work, but it also provides a stimulus to improve the very thing that you need. That's the trick. That's the trick, right? So to just get real brass tax about it, it would be once a week,
Starting point is 01:58:30 at 90 seconds near maximum heart rate, could I do more? Could I, you know, could I do five or six of those 90 second bouts? No question. You can do, as long as you touch that max heart rate, I'm good, right? Ideal world, probably four to eight.
Starting point is 01:58:45 In that single session. Ideal, okay. Right? If that takes you 20 seconds or 90 seconds, it's fine. If you want to do 30 on, 30 off, you want to do 20 on, 40 off, 40 on, 20 off, those numbers don't matter. And is there an interference effect of this on the other sorts of training that we've talked about?
Starting point is 01:59:00 It actually tends to be complementary. The evidence available suggests that this high interval stuff is more likely to be complementary to hypertrophy training, probably because of lactate and some other cool things, which are very beneficial molecules that people don't understand. They think it's bad, it's actually a hugely beneficial thing.
Starting point is 01:59:19 It can be interference, it can provide interference. If calories are not accounted for, if rest is not accounted for, and other things, but in general, it's probably okay. I wouldn't add it to your equation if you don't need it for maximizing hypertrophy, but for the person who wants to just get well-rounded physiology, yeah, I wouldn't hesitate
Starting point is 01:59:38 to do these even in the same session or different sessions. Terrific. So, and if that's done once a week, and the 150 to 180 minutes or so of zone two cardio is done, you know, in the rest of the week, you're person's doing their strength and hypertrophy training, we would hope. What other sorts of endurance practices could one incorporate? You mentioned muscular endurance, like the ability, like a wall sit or the ability to do a plank. Is that something that is that useful for anything? Yes. Is that doing planks in wall sitting? No, no, it's extraordinarily useful.
Starting point is 02:00:11 Let's hold on musklanderids. I want to finish one more thing on this side. So if we're building this week of endurance, once a week hit that number, if you can do repeated bouts, we talked four to eight, that's fantastic. If you can't muscle the, the, if you can't manage the mental energy every week, do it every other week. It's still very good, right? Because I get it. Like I'm a working person too. And sometimes you're just like, I cannot, like those workouts feel incredible afterwards, but man, they are daunting. If you love this stuff, you could do it four times a week. If you hate it though, it's not realistic to think you're gonna be able to knock this out.
Starting point is 02:00:49 You're gonna end up doing 70, 80%, which is not gonna get you the benefits. So just don't do it. You really have to hit that. You gotta get up there, close. Have someone chase, I always say, when doing this kind of work in my mind, I'm thinking that I'm basically being chased
Starting point is 02:01:04 by somebody with a syringe full of poison. And while there are other ways out of the situation, and for the benefit of what we're talking about, the one I'm referring to is to just run. Yeah. My motivation is typically, if you just get this done, we're done in a couple of minutes. Just get it done. Like, don't go here if you're not going to do it, when you show up, check in and it's over really quickly. Breathing down regulation after 100%. You have to, right? It's a easy, huge key. So if you absolutely can't do it, do it every other week. That's twice a month. Give me twice a month.
Starting point is 02:01:35 It can be done on the road. It can be done at 20 minutes. Like, do a really good, thorough warm up. Don't just jump into those by the way right away. It's not going to be as beneficial. Really nice, good sweat broke, a really good warm up and then give me four minutes of hard work and we're done Right get out of there If you want to use like a bath or hot thermal stress to kind of like a in that warm-up process
Starting point is 02:01:56 Fine getting a sauna getting a hot bath. Get really hot get up there warm up knock it out. The whole thing is 20 minutes plus five minutes breathing I'm gonna start doing this. It's so bad You got a bike right there. Yeah, I've got all sort of every every every room in this studio to that's a different piece of equipment It seems so I want that once a week or less likely every week if I have to I want that physical activity piece Call it whatever you want long duration thing Ideally you'll do as much of that through your nose only You're not gonna be able to do the interval stuff at nose only. Don't even try.
Starting point is 02:02:27 But if you can go that whole 30 minute time or 20 or 40 minutes, whatever it's going to be, that's actually a good way to regulate intensity. So it goes hard as you can while still being able to breathe through your nose only. If you have to open up your mouth a little bit, fine, but try to stay there. What you'll see is very quickly, you'll be able to increase your work output while just breathing through your nose, which has a bunch of other benefits. The other piece I want is this middle ground, which is, can you sustain hard work for eight to 12, maybe as little as four minutes? I'll give you four to 12 minutes. This doesn't have to be quite as high as the first one. You don't have to get to a and max. But can you get somewhere in the 80% range?
Starting point is 02:03:08 And can you hold that for four minutes? Maybe give me two minutes, two minutes to rest, and do that twice, something like that. I deal situation is what a runner would do is like what we'll call mile repeats. Because they're running four or five minute miles. Whatever time it takes them to finish, they're going to rest that. So it's a one-to-one work to rest ratio. So a five minute mile,
Starting point is 02:03:29 rest five minutes and go again. That's probably pretty unrealistic for a lot of folks. Well, the five minute part is unrealistic for most folks. For me, it would be eight minutes, eight minutes. Probably something like that. Well, in your particular case, just do the 800 meter. So do 800 meters. Do something that that. Well, in your particular case, just do the 800 meter. So do 800 meters. Do something that takes two to six minutes to work. It is a lower intensity than the max stuff, but is a much higher workload. That is probably going to give you, you might even argue, the most carnivascular benefit,
Starting point is 02:04:00 because it is sustained work output. And that's very critical. The downside of kind of like that conversational pace, it's physical activity, it's movement, it's blood flow, it's lymphatic drainage, it's not very cardiovascularly challenging that. You're just not going to get an optimal health from just walking actively.
Starting point is 02:04:19 So two to six minutes of hard work, of hard work with an equivalent amount of rest in between and then repeat how many times. Once, if you have to, if it needs to be one rep, if it needs to be a six minute thing, and then down regularly breathe twice, if you can do that six times, eight times, whatever you can really do, and you can just take those long of the training session as you want or short.
Starting point is 02:04:44 Exercise choice can be whatever you want or short. Exercise choice can be whatever you want. So again, you can do sled pushers or it could be a kettlebell circuit or any combination of things where you're just you're working and you're not giving yourself a break. You have got to be able to hold on at a very high waste product production level as well as a high demand for energy and then bring it down. for energy and then bring it down. And breathing during this two to six minutes of hard output is mainly through the nose or combination nose and mouth. Or is that getting too technical? Well, it's probably like I like it, but you tell me if it's too technical.
Starting point is 02:05:17 You're going to try to maintain nasalone as much as you can, but you're going to lose it at some point. You can go through their Brian and Rob's gear system and learn more and then you can kind of see what gear to be in. If you have to go nose in, mouth out or something like that, but I don't really care too much honestly in that range. I'm getting most of my nasal only stuff at night and training and everything. So if you have to open up the throttle there to get the work done, that's okay. Oh, then we'll actually go to your answer your question, which was Muscle and endurance. Let's go back to that piece.
Starting point is 02:05:51 Muscle and endurance is incredibly important for general maintenance of joint health. In other words, you have got form follows function, right? It's a very classic science-y physiology saying, meaning you've got a couple of different, there's a bunch, but to make it easy, two different types of muscle fibers. Fast twitch and slow twitch. Fast twitch fibers tend to be, but they're not always bigger. They contract with a higher velocity. That's why they are called fast twitch.
Starting point is 02:06:17 But they tend to be more glycolytic and thus fatigable. Slow twitch are tend to be smaller, not always. They are more packed with mitochondria that we're generally better at burning fat as fuel but contract lower velocity. Well we have these two types so that we can regulate function more. You have some muscle groups that we're going to, sorry, let me go back up a quick second. Each individual muscle in a human body has a combination of some amount of fast and some amount of slow.
Starting point is 02:06:46 That percentage of fast versus slow differs from muscle to muscle. So it also differs from person to person. Easy example is your calf muscle. There's three, but there's two primary muscles in your calf. One's called the soleus one's a gastroc. The gastroc is the one where if you take your toe and point it towards your face and then flex, that's the one that pops out on the medial side, the inside. The sole is what we call an anti-gravity muscle.
Starting point is 02:07:11 And it is generally about 80% to even 90% slow twitch. And that's because it's supposed to be contracted lightly all time, supposed to be on permanently. It's meant to keep, we call it anti-gravity because it's meant to keep you erect up and moving. Your spinal erectors is supposed to do this various muscles for postural or are generally slow twitch muscles. So we're supposed to be on all times, not produce fast, not produce force,
Starting point is 02:07:36 but don't get tired. The gastroc is the opposite. It's not activated very often, but when it's activated, it's meant for extreme propulsion. This gives us the ability to reach up and scratch our eyeball and also punch somebody. We have to be able to regulate force output,
Starting point is 02:07:51 which is going back to Heneman, right? Controlling what we use and what we don't use while also not wasting energy, which is the downside of activating a big threshold motor neuron is it requires a ton of energy. It's a more efficient mode of energy, but the total amount is really, really high.
Starting point is 02:08:06 So muscular endurance is going to help those slow twitch muscle fibers and slow twitch predominant muscles maintain their working job. So if you lose your muscular endurance ability in your spinal erectors or your calf, you're going to start slumping into bad positions. You're going to be getting, putting joints in a movement pattern that they're not going to be the most happy with. So it's more than about then being able to just maintain a two minute lost squat.
Starting point is 02:08:34 It's about maintaining joint integrity and allowing that musketeure to not fatigue when you ask it to do heavy and fast. So what I mean by that is you've got a whole combination of muscles in your shoulder. And we will generally call these like the rotator cuff muscles. Well, let's imagine those slow twitched, postural muscles get fatigued. And they start to lose contractile tension. And then you go to do something heavy or fast or an emergency situation. Those are already prefatigued. You're going to rely more upon the faster muscle fibers, which are there less for postural integrity.
Starting point is 02:09:10 You're likely to get out of position. And this is a whole recipe of like, God, why is my shoulder disherting? Got my back. That's very often a case of the slow-touch fibers, the slow-touch muscle groups, losing muscular endurance. So you need to build that back up so that they can control and hold the joint in the position so the faster it's virus is because they can contract with force. I'm hoping that what I'm going to say next meets what you said accurately. My experience is that getting injured, lifting weights
Starting point is 02:09:40 or even doing housework or yard work almost always happens when I'm not paying attention fatigued that's kind of obvious but also getting in position to initiate a movement setting down a weight or lifting weights off the rack or or picking up dumbbells that's almost always when I seem to activate this lower back thing that happens every you know six or eight months and what you're saying if I understand correctly is that this muscular endurance from wall sits or activate this lower back thing that happens every six or eight months. And what you're saying, if I understand correctly, is that this muscular endurance from
Starting point is 02:10:08 wall sits or planks or things of that sort, maybe you could give us a few other examples of these, can help us because they actually prepare the system to do what we normally think of as the more intense work. So it's really that, it sounds like it's really the architecture of the body that includes nervous and muscles and everything else, of course, that lets the limbs and other kind of action end of the body do its best work. Yeah, let it express its own power and force. Yep.
Starting point is 02:10:36 We actually landed on one of my final laws of strength and conditioning, which is similar to what I said earlier, right? So I said, exercise exercises do not determine adaptations, application determines adaptation. So it sounds similar, but it's quite different. There are no good or bad exercises. There's only good or bad application. Here's a great example of that, right?
Starting point is 02:10:58 So you do not get hurt deadlifting because deadlifts are dangerous. You only get hurt deadlifting because you either got in bad position, you got in bad position because you either started in bad position, which is one of the things you just said, or you ended up in bad position. You did too much volume, you did too much intensity,
Starting point is 02:11:19 or you did too much complexity. Those last three things all hurt you because they result in the first one, which is out of position. Or another way to think about this is if it's not like a visible change in position is stress got put into a part of the system that should not absorb that much stress. So you did too much of it, you did it too heavy, you got fatigued and so you broke position. You got too heavy, so you broke position. You made that exercise too complex. You put too many moving parts in it.
Starting point is 02:11:48 You put too many joints in it and you got it in a position. You did that too many times over time. Now we've led for either an acute injury, bam. Back pops and you fall on the floor or it is like, man, this thing is hurting over time. All these are the results of the same thing. So you cannot ever blame the exercise for causing the problem. It's always either the user or the coach. You programmed way too much here and I can't handle that position or you yourself went into it too much.
Starting point is 02:12:15 So if you're getting these little tweaks and problems going on, you've made an error in one of those things. So simply back off, reduce the complexity, right? Give yourself more stability, less moving parts, do less volume, do less intensity. In fact, if you look at the people from the physical therapy world in terms of the pain, literature,
Starting point is 02:12:35 it's very clear that just stopping a movement is very rarely going to work. What you want to do is back off all the way down to just below that threshold of, that's what aggravates it. And you want to train right there. That's going to allow you to do two things. Number one, tissue tolerance, and then number two, desensitization. A lot of pain stuff, and you can probably speak a lot about this, is especially with things like low back pain, is there's not necessarily often much damage there. It's a lot of hyper hypersensitization of just pain signal, pain signal. Omitting the
Starting point is 02:13:07 movement entirely does not get that signal to go away. You need to train just below that signal and desensitize it. So you want to make sure that the Muscle and Durant allows you, you're just putting volume right below where you start to get a tweak and it is beautifully effective for that. I've experienced this right side lower back pain for years, sometimes shooting down the hip, the two things that really helped were doing anterior tip work. So you know, hats off to Knees Over Toes Sky,
Starting point is 02:13:33 Ben Patrick, who has created a lot of popularity around tip work, but I- Turns out joints, full range of motion, you're in a better spot. Yeah, the, something about stabilizing the stuff from the knee down helped my back and then also some some neck work and friends of mine are always teasing me that my gym is filled with the most bizarre equipment, you know, it doesn't look like any other gym. A lot of it's just designed to keep me healthy and still training, but I love this idea of getting right at the below the threshold of pain activation
Starting point is 02:14:02 and not simply going into to complete non-action or just taking complete rest because that actually can be detrimental. I'd love to talk about a few items that support training of all kinds and where there's a lot of confusion and indeed misconception and mystery and just get your take on these. And I just want to acknowledge at the outset that for some of these there's a lot of science, for some of them there's less science, but there certainly is a lot of experience in your camp. And those categories are cold, heat, and hydration. Because obviously whether or not you're a runner, whether or not you're strength training, if you're a
Starting point is 02:14:40 human being, you need to hydrate. But in terms of work output and physical work output, maybe you can cognitive work output, maybe tackle hydration first. There is what I call and what I think is now come to be known as the galpon equation, which you really do deserve credit for because I think that people realize that there are a range of solutions out there, but there is a really a desperate need for straightforward solutions that work for 75% of people, 75% of the time. So hydration is key. Maybe you could underscore just how, how key it is for us. And then what is the Galvan equation as I call it, and I think others are now referring to it.
Starting point is 02:15:22 Yeah. Okay. Benefits of hydration, slash consequences of mishydration. So whether that's dehydration or overload, physiology has aromatic curves. Right? Not typically we think about this in terms of toxicology. So what this means is at some point, giving you a dose of something, testosterone is a very easy example.
Starting point is 02:15:44 If you are clinically deficient or low in testosterone and I give you a dose of something, testosterone is a very easy example. If you're clinically deficient or low in testosterone and I give you a little bit and it brings you back to a normal range, you generally see an improvement in health and functionality. Taking you though from normal to super high doesn't always necessarily provide additional benefit. In fact, if you continue to go, it's going to provide detriment. Everything has its current. Then some things are hermitic stressors, which means like a small, short, fast insult is actually beneficial because then you come back bigger, faster, stronger. And that's how adaptation works. Basic hormises. Okay. Hydration is the same way. So at
Starting point is 02:16:17 the end of the curve here, if you are under hydrated, well, I'll know, you could die. Right. You have to have things. In fact, water is the only thing that is ubiquitous across biologies in terms of every living thing has to have it. There's no other vitamin, mineral nutrient that is required among all living things with the exception of water. So that should give you a pretty good indication of it's important day, right? Like, you got to have this thing. Down here at the bottom, if you're dehydrated and it give you more, it's beneficial effects.
Starting point is 02:16:46 However, if you are up the top already and I continue to give you more water past that, now we run into actual problems and we can give what's called hyponotremia, which is more common than people realize. Nitremia being actually not referring to the water but the sodium concentration being too low. And you've probably talked about that
Starting point is 02:17:04 at a length of why that's an issue. If sodium potassium balances inside, outside of cell, come off you heart stops. Muscle contraction ends and all these things. So you don't want to be over or under hydrated. So understanding this rough equation, I sort of loosely calculated one day, is helpful for that. I think the most context is talking about how much water to drink throughout the day and then how much water to drink during exercise. So
Starting point is 02:17:29 the very easy answer is half your body weight analysis per day is a very loose guideline for total amount of fluid consumption. So if you weigh 200 pounds and for 100 ounces of water, it's like a very easy number. If you hit that, you're probably I'd'd say, 90% of you are good, 90% of the time alone. If you then go to exercise, you need to then account for that fluid loss with exercise. And in general, you want to consume 125% to 150% of the amount of weight you lost in fluid. In other words, if you worked out and you were 200 pounds naked and you ended your workout and then you dried off and you weighed yourself again and now you're 198 pounds, you lost two pounds of water. That's 32 ounces. You want to drink back
Starting point is 02:18:14 about 125% of that. So instead of drinking 32 ounces, I want you to drink 42, 45, like something like this. Because one of the reasons why is unless you're drinking something that is isotonic, meaning the same exact concentration in your blood that you're in your fluid, you're just going to go closer to that hyponotcemia. You're going to get a bunch of bare-er-reflective responses and you're going to actually think you have too much fluid and you're going to urinate it out. Which is not weighing myself before and after workouts and is there a Shorthand version of this that you know after training for an hour. I should drink at least X mary bounces
Starting point is 02:18:53 Yeah, that's assuming it's it at kind of it taller, you know, I'm not sweating super heavily. Yeah, um in that particular case You could probably go something like If everyone in the world did I I don't know, 12 to 20 ounces, that's probably pretty decent. And they're probably doing that, right? Yeah. And what about electrolytes, a consuming salt potassium and magnesium? But that thing only works though if you're coming in at optimization. And this is the problem.
Starting point is 02:19:23 This is why you have to flag this starting with a good, total daily amount of water. Because if you're coming in and you're like, oh, I drank two or three glasses of water a day, then you might need to drink 50 or 60 ounces post workout, because you're way behind. So that like, oh, 12 ounces or so works if you're already generally very well hydrated.
Starting point is 02:19:41 And if people are drinking four to six glasses of water a day, but they're also drinking a lot of caffeine in any form, then they're going to be excreting more water in most cases, right? Well, because caffeine is a diuretic. Okay, it kind of is, but it kind of isn't either. It's not the diuretic that we used to think about it as. It is still fluid consumption. So it's only a diuretic.
Starting point is 02:20:02 If it causes you to excrete more fluid than it actually was being in tech. So if caffeine intake is in a normal range, I don't have to worry about the diuretic effects. If someone is drinking 12 cups of coffee a day, or they're taking caffeine pills or something, now the excretion is going to outkick the coverage. So now we're now problems, right? Because there's no fluid consumption with the caffeine pill. So in general, things like tea, consumption, like I'm not super worried about those things. You can count those torches total fluid intake if you want. So if you're like, I drink 60 ounces of water
Starting point is 02:20:36 plus 20 ounces of coffee and then you're going to add that all up and you're going to be totally okay. So natural, you also have problems with synthetic forms of caffeine versus natural forms of caffeine. Natural forms are pretty okay. So coffee tea, etc. Yeah, all that stuff. Kill form is where it gets tricky. Always, like always, right?
Starting point is 02:20:57 So general, just eat real food and things. You're gonna be just fine. The last piece to consider is your diet quality matters because the fluid content in your food can vary wildly. So something like a bagel might be, you know, five to 10% water or something like a watermelon is 98%, 95%, something in a huge range, even meat is very high percentage of fluid intake.
Starting point is 02:21:27 It's a really high. Even after you cook it, there's still a lot of fluid in there. So if you're eating a whole food, mostly whole food-based diet, your endogenous hydration is actually pretty high already just from your fluid. If you're eating a very highly processed dehydrated, oversalted diet, You're way low on hydration just in your food. So you have to factor all these things, and in fact, one of the things that happens to us constantly with folks that go from a highly processed,
Starting point is 02:21:54 low quality diet to a high quality one, is they're just peeing on stop. I'm like, what the hell is going on? I'm like, well, you actually have brought in 60 additional ounces of water in your diet relative to what you used to have. And you've gone from 10 grams of sodium there to four to two, sometimes one, sometimes it gets very low because you're not like salt.
Starting point is 02:22:13 Are you salt in your food? No. Okay. Well, we don't have sodium intake then, like we're weighed down. So everything that we're considering is based on that. So let's assume someone's eating a pretty well balanced diet. They're drinking 60 ounces of water, and maybe some caffeine, coffee and tea, things like that.
Starting point is 02:22:31 We don't exactly know the optimal amount of sodium one should intake. It is very clear. High sodium concentrations are still associated with a lot of negative health outcomes, especially in combination with pork physical activity and combination with low-food quality and other comorbidities. That's a very bad thing. You need to be very careful about those things. If everything else is okay, we're okay playing with a little bit of higher salt. In fact, you're probably going to feel better. You're going to feel generally pretty good.
Starting point is 02:23:00 You just, it needs to be very clear. If you are overweight, highly stressed, and you don't have a lot of these things ticked off and you have known core momentities, you really need to pay attention to salt intake. It can be very nasty. So that being said, what we're generally going to look at, folks, is, are you at least, can we categorize you as a low sodium or high sodium sweater? If so, there's a whole list of electrolytes you can look that are going to have something like 200 to 400 milligrams per serving. And there's a whole list of these things.
Starting point is 02:23:31 If you're low sodium sweaters, I'm probably going to send you after one of those. If you're a high sodium sweaters, there's a lot of electrolytes supplements that are closer to 6 or 800, even a whole gram per single serving size. So you want to play with that. I very, you know, if you're a low sodium or high sodium sweater, we actually have an episode on salt. We put out that, um, where it's coming out soon, it hasn't come out already, which is, uh, you know, when you look at the hazard
Starting point is 02:23:56 ratios, yeah, or salt intake, um, basically your probability of really bad things happen to you goes way up as you get towards, you know, a lot of sodium intake, you know, 10, you get towards a lot of sodium intake, you know, 10, 12 grams per day. And this is translated to teaspoons of salt, et cetera, but also very low sodium intake is a problem. No question about that. It's not a perfect U-shape, it's kind of a J-shaped curve or a kind of hockey stick shape, more or less, but how would I know if I'm a low sodium or a high sodium swimmer? Yeah, so you can be so- Would I just count with my sweat or have someone else do it?
Starting point is 02:24:26 Well, you can. Yeah. Find a super friend who will lick your sweat for you. That's the same with how. No, no willing volunteers that I'm aware of. But would I be able to tell? Yeah. You can get sweat testing done.
Starting point is 02:24:36 Actually, you have a number of options. The kind of the original one that most of us use in the background for many years is called Lebelin. They'll send you out a little patch, you can wear that, send it in the lab, and the little measure it directly in the lab and send it back is 150 bucks or something. Do they bring you into low, medium, and high? They're going to do that, but they're going to tell you exactly the milligrams. Then they're going to actually tell you what products and stuff that are exactly matched. Do you do this with that with professional athletes?
Starting point is 02:25:05 We have many times. Yeah. Interesting. You can do a more consumer grade version gate raid has a patch for 25 bucks you can get two of them. You can put that patch on your left forearm and download the gate raid app and you can do a workout measure right there and click it over and they'll tell you exactly not only higher load but again they'll tell you the milligrams of sodium that are in your sweat and you can figure out again kind of high
Starting point is 02:25:28 medium or low. Interesting. I do much better on a slightly higher sodium intake. Most do. But in my carbohydrate, I do e-carbohydrates on one of those that it is pretty moderate but I try and eat clean food. So I noticed and I tend to be slightly low blood pressure. So again to reiterate that the warning there that if somebody is a prehypertension or has hypertension
Starting point is 02:25:48 or obese, you really do need to be careful with your sodium intake. But many people seem to find that they feel better when they increase their sodium intake. And they're still in that healthy portion of the hazard ratio. Most of the athletes, I would say in general, we're going to go higher in salt. When they come, we're going to run their stuff and we're going to add salt almost always. Very few times have I gone, ah, we're gonna go higher in salt. When they come, we're gonna run their stuff and we're gonna add salt almost always. Very few times have I gone, ah, we need to cut this back. One of the exception of the ones that come in that eat like 14 year olds, and I'm like,
Starting point is 02:26:13 okay, you're at 15 milligrams, are you 15 grams a day? Cause you're eating nothing but garbage. So we're like, we're gonna come down, you're gonna feel way better, all this bloating and everything else that's gonna happen. Go down. You can do that. They're bios more, they're biosensors that are coming out. They're not available yet, but they're coming very soon in this space. They're going to be able to
Starting point is 02:26:31 give you real-time metrics on salt. So you can pay attention to those. I haven't seen one and used one personally, so I don't want to espouse about how good or bad it is, but I know that those are coming from a handful of companies. An easy way to do is just look at where a hat or where some sort of headband or something and do your workout. Take it off. If you see a just huge white band or if it's completely clear, and that's going to tell
Starting point is 02:26:59 you, big white band, you're probably a high-cell sweater. Completely clear, very little coming out. That's great. I can see the post on Instagram now, people showing their salt band from sweating. I mean, obviously salt is so essential for so many physiological functions. You don't want too high or too low,
Starting point is 02:27:16 but if you're losing more, it makes sense. You would need to take in more. So half of my body weight announces as a just foundation of fluid intake. Coffee and tea could be included in that, but that should probably mostly water or things similar to it. And then during exercise, the, how do I wanna think about this again?
Starting point is 02:27:37 Let's say I'm a high salt output then I'd wanna drink maybe 40 ounces of water with or more. Yeah, okay, I'll do this easier. Let's talk about pre and mid and post, right? So what to drink pre? If you come in having hit these rules, you're okay. And pre workout can be as little as like five or six ounces. Basically a couple of sips of water, fine.
Starting point is 02:27:59 If you come in poorly hydrated, then you maybe need to go more like 12, but here's the deal. If you start off a session in a bad spot, you maybe need to go more like 12, but here's the deal. If you start off a session in a bad spot, you're not going to catch back up. Like you're in trouble. Let's say you come in, you follow direction. 500 milligrams salt before, 500 milligrams after.
Starting point is 02:28:19 Very easy rule. Pick whatever source you want. That's a couple of sprinkles of table salt. If you want Himalayan, that's fine. You don't have to. Himal a couple of sprinkles of table salt. If you want Himalayan, that's fine. You don't have to. Himalayan is actually a fairly low sodium salt. So it's not the best for this purposes.
Starting point is 02:28:31 If you're higher, salt or sweat or a little bit more. If you want to go choose an electrolyte of which there are infinite, you can look on the packet and it'll tell you, 250 milligrams per serving or 400 or 600 or whatever happens to be, but around 500 per 500 posts is a very general rule.
Starting point is 02:28:46 And then during is thanks to you, my famous Galpin equation now that is all over the world. All I did is I took the literature and I said, okay, in general, the research shows pretty clearly two milligrams per kilogram body weight over 15 minutes seems to put you in a pretty good spot. Most people don't think about kilograms or milliliters. So can I just run that over and then it turns out
Starting point is 02:29:06 it's about your body weight divided by 30 analysis. Like that's all you have to. Body weight and pounds divided by 30. Yeah, exactly, right? So you weigh 200 pounds divided by 30 and that's number of ounces. You're gonna wanna go every 15 or 20 minutes or so. So I'm getting that amount every 15 to 20 minutes
Starting point is 02:29:23 throughout the training. And now in the weight room, that's pretty easy to do. Because there are rest intervals, but people will need to do this while running or cycling. And that can cause a little bit of gastric distress if you're not used to it. Is that right? You can learn to run with some water in your belly.
Starting point is 02:29:40 100%. The gut is very trainable in a lot of directions, but in terms of fluid, as well as carbohydrate, which is another thing that is going to get people, but that's the very trainable. It'll be uncomfortable initially, but you'll quickly get into it. The better solution for those folks, just come in hydrated. You might not even need water. You could probably perform just fine. So the ones that don't have as much of an opportunity, you really have to emphasize walking in. We have this problem with like professional golfers.
Starting point is 02:30:10 They have plenty of time to drink water, but they're so focused on the shot and there's a lot of variables coming up. Once they hit their shot and they're moving on to the next one, they're thinking about, I mean, they're going over a scorecard of 185 yards away. Can I go 184 and a half yards? Can I go 186 yards, what's the slope of that, what's the wind up here, what's the wind up there, like it's just a thinking and they just forget. Even though they have 4 and a half hours, so we have to make sure that they immediately get off the course, we go right into recovery as hard as we possibly can. They wake up the next morning, they're in a good spot, we crush recovery, and now
Starting point is 02:30:43 it's okay, if you can remember to drink this, great. If not, we're still fine. If it's not a big deal, and you have time like in a lifter, because I deal with that problem with fighters too. Like, we can only drink so much in the middle of a fight. A couple of steps over there, but we can't go mix them. Two milliliters, it's like, can you get a couple of steps in?
Starting point is 02:31:02 Oh shit, forgot, like, it's not gonna happen. So we have to take more of an emphasis before and after. So start your recovery process immediately, and then come in the next day, that's your window, and then whatever you can get in during the workout, that's fine too. If you're a higher salt sweater, I said to do it in 500, 500, maybe go 750, 750.
Starting point is 02:31:20 If you have a longer bout of exercise, especially if it's hot or humid, then you might want to consider some salt in the workout as well. And 300 milligrams during the workout, totally fine. It's enough, if it is a really long workout and it's really hot and you're gonna lose pounds during it, you need a specific strategy.
Starting point is 02:31:40 If you're gonna lose less than a pound, you don't need to worry about it. You're gonna be, is not gonna be enough of a detriment for you to really care. So that's a rough rule. Now, if you're 200 plus pounds, maybe that number moves from one pound to two pounds. But really, the number we're looking at is what 1% of your body weight? If you're losing more than 1% of your body weight, we need to start caring. If it's less than 1%, it's not going to really pay that much of a difference. Okay, so for myself, because I don't get super technical, I don't wear any devices
Starting point is 02:32:08 besides a wristwatch. Thanks, the very attached to this watch, or it's attached to me, I suppose. My body weight in pounds divided by two, that's what I'm going to try and get across the entire day as a kind of baseline, and then my body weight in pounds divided by two, that's what I'm going to try and get across the entire day as a kind of baseline. And then my body weight in pounds divided by 30, during the workout, every 15 or 20 minutes that I'm going to try and consume that amount. And then I definitely do better when I increase the amount of salt that I'm taking in, any more than 500 to 500 milligrams to a gram of salt several times a day actually. But I'm not eating that often, which leads me to my other question, which is I prefer to train fasted or semi-fasted, meaning first thing in the morning or within an hour or two of waking, when I've excepted and fasting while I'm asleep, or having not eaten anything for three or four hours before, I just feel lighter and more energetic.
Starting point is 02:33:05 If that works for me, is that okay or should I try, is it better to eat something before one of the trains? Personal preference. Easy answer there. It depends on, of course, how hard you trained, what the training was like, what sport you're involved with, how many telecoms and such, but in general, personal preference for the average person. Yeah, that probably handles 90% of the questions about that. Cold. Cold showers, ice baths, and cold immersion up to the neck. I always preface this by saying
Starting point is 02:33:38 there are not a lot of studies. There are some, but not a lot of controlled studies looking at cold showers because it's harder to control the variables of where people stand. So I would say if you have access to cold immersion of some sort, ice bath or cold immersion, great, but if you don't, cold showers would be the next best thing. The lower goes that if you do an ice bath or cold water immersion after strength or hypertrophy training, that you are short circuiting some of that. The lower also goes that cold showers might be okay, and my interpretation of those data and that discussion
Starting point is 02:34:13 is that all that is probably true, but I have a hard time imagining that the effects are so robust that it can completely prevent strength gains and hypertrophy, such that my stance for myself is trying to do the cold exposure training away from the strength in hypertrophy training. But if you can't do it any other time, right afterward probably isn't going to throw my whole system out of whack and prevent the improvements. Am I deluding myself? A couple of caveats, you're number one.
Starting point is 02:34:47 I would say I have a personal vested interest in cold. I've been around this stuff for a long time, being involved and being an advisor for XPT, and being in this space a long time, I'm a big believer in cold, especially cold water. Deliberate cold exposure, 100%. So that being said, I do think getting into an ice bath immediately after a hypertrophy session is getting pretty close to you just should have done the session.
Starting point is 02:35:15 It is detrimental. Good to know. I wouldn't do it. I guess is the most blunt way to put it. If you're like, hey, I'm not super concerned with growing muscle, and I want these other things that come with cold water immersion. Fine. It's not zero. It's not zero. It's not taking you backwards. How much does it cut you down? I don't know. We don't know that that'd be a difficult number to come up with. Is it 1% reduction? No, it's more than that. Is it a hundred? Not even close. I don't know where it lands though.
Starting point is 02:35:48 It's enough though for me to go. In general, best practices don't get in the ice immediately after a workout. How long should I wait? Well, in theory, the best answer we could give you would be four hours because of what we talked about earlier today of going, okay, immediately you've got the signaling cascade that takes seconds.
Starting point is 02:36:03 You've got gene expression that's happening in this rough four hour window. After the genes have gone off and now you're just going through the protein synthesis process, the signal's already there and it's gone back down to baseline. So then we're introducing, our introducing cold here is not going to disrupt that signal. That's a very non-scientifically founded because we don't know at this point at all. What is very clear though is if you get off your workout goal right into the ice, it's probably 10% attenuation of growth. I don't know, maybe more depends on the person.
Starting point is 02:36:33 Some people, if you look at the individual data, it's a pretty bad. It's enough to where it's like, that's a really big deal. The benefits of the ice, I don't think now outweigh the benefits of the hypertrophy training. What about cold showers? I don't think cold showers are going to do much. If you've been in both, you know that this is like we're not playing the same game here. Right. An ice bath or a true cold water immersion up to the neck with limbs in if for one to five minutes is a completely different stimulus than in the cold shower.
Starting point is 02:37:01 Especially also compared to a similar like cryo. It's not even the same thing here. So in general, I would say don't do those cold shower. I don't really care. Can you work it out so you don't do them the same time? That would be my hope, right? I would actually prefer you to do the cold before. If you really had to do it.
Starting point is 02:37:19 Certainly we'll wake you up. Get that adrenaline burst. No, we've played with that actually years ago, doing that. There's actually some fun stuff you can do with the endurance piece with cold stuff, but it's totally not feasible for most people because you're getting water everywhere, you're gonna jump on your bike and just get shit,
Starting point is 02:37:35 and it's just a giant mess. It's fun, but yeah, I would say walk away from it if you can. That's actually, it's where I stand based on the data, based on my intuition and experience. I don't think it's a good thing to do. Now having said that, that's actually, it's where I stand based on the data, based on my intuition and experience. I don't think it's a good thing to do. Now having said that, that's mostly concerned with maximizing hypertrophy.
Starting point is 02:37:51 Strength is not as clear. There are some data to show at an actual block, strength adaptations, but because of what we talked about earlier, the mechanisms and the drivers are different. And so I don't think it's as big a concern for strength development. Though I would still generally say's as big a concern for strength development, though I would still generally say if you can get away with staying out of the ice immediately
Starting point is 02:38:08 after the workout and you can at least wait a few hours, that's the better approach. Less concern with strength, more concern with hypertrophy, in terms of interference effect. If you can do it on off days or before or any other time, that's the place to land. That's generally when I try to do it. Just kind of throwing out an extreme case because I get to ask that question a lot. What about the use of ice bath or cold water immersion or cold shower after endurance training? Okay, so a couple of interesting things here. You mentioned we don't have a tremendous amount of data
Starting point is 02:38:37 on cold water immersion overall. So a lot of this is moving. There have been some papers to show that cold water immersion can actually enhance mitochondrial biogenesis. And actually even for endurance stuff, it's been shown to cause improvement in endurance adaptations relative to not. It's not enough for me to be truly confident in that statement yet. I would like to see that repeated, not that I have a problem with the paper, the methodology
Starting point is 02:39:03 that they use in that particular study. But it's just a weird thing. So I want to see this repeated more often. So I have less concern with doing it immediately post endurance because you could even argue that there may be some benefit. I don't think you need to go out of your way to try to make sure you get an ice immediately afterwards and thinking you're going to get some massive adaptation. We use ice at decent amount when I can get athletes to do it, but this context is different.
Starting point is 02:39:29 Number one, when we're in camp and we've got a world title fight coming up or something else, we've just pitched in a major baseball game, I am not concerned about hypertrophy. I am not even concerned with strength development. I am now pushing towards recovery. There's a paradigm that I think is important with all of these things to understand, which is, are you pushing for optimization or adaptation? When you're pushing for adaptation, you don't want to block the signal for adaptation. This means less recovery. You're not going to feel as good, and you probably should be hedging towards stress. When you're pushing for optimization, it's the opposite. So if I'm in season, and I had
Starting point is 02:40:04 a picture just throw 125 pitches, I'm not trying to cause adaptation. I'm trying to recover as quickly as possible because four days from now we got to do this again. And I got to do this across 162 games. You're going to play five days in a PGA golf tournament and you're going to have to do it again every week for a bunch of weeks in a row. I need recovery as fast as I possibly can.
Starting point is 02:40:25 So if I'm blending adaptation fine, I'm not actually trying to do so. I'm trying to optimize. If you spend all of your time in one of those two areas, you're going to have problems. So you need to be judicious about thinking, is this a point in my life or a training cycle that I want to cause adaptations?
Starting point is 02:40:40 Or am I trying to optimize? You spend too much time in one of the other ones, again, you're going gonna have problems. So that's in generally how I will treat the ice for all those adaptations. What about heat? Yeah. When, and I'll frame this question differently,
Starting point is 02:40:56 because I'm sure there are a number of ways in which heat can short-circuit all sorts of things. I mean, heat in excess can kill you. Yeah. It can shut down fertility. It can in excess, right? It can do all sorts of things, but it can also increase growth hormone, increase vasodilation, improve one's ability to sweat, which can be very beneficial in a number of contexts. For the typical, for 75% of people, 75% of the time. When do you think heat is most useful?
Starting point is 02:41:25 And here I'm referring to dry sauna or wet sauna. I'm not specifically talking about infrared sauna because the data there are a little unclear to me. And I don't even know that my sense with infrared sauna is they don't go hot enough for my particular taste. You and I have a similar taste there. Okay, for not crushing 200 past, I'm not interested. Right, and my sense about infrared sauna
Starting point is 02:41:44 is that maybe I haven't seen the data? Is that, but that a lot of people like it because they like the way they look in the infrared sauna. It feels cool, it feels like you're doing something unusual. Now infrared lights are beneficial for other reasons, actually for mitochondrial health in the retinas, they're good data, but infrared sauna to me, they never goes hot enough.
Starting point is 02:42:03 So I'm talking about 200 or hotter, maybe 180 to 20. Obviously do what's safe folks and heat all the warnings about pregnant people not going in size, etc. I assume we're lumping in hot water immersion. Hot water immersion, so hot baths, hot sauna. When would you like, when do you think most people could leverage sauna or hot baths to benefit their training and fitness and health.
Starting point is 02:42:26 Yeah, okay. I have a handful of things to say about this topic. One of them is you never have a hard time convincing people to get hot. Everyone feels good. Yeah, I can't hot bath. Can you take more hot showers? Sure.
Starting point is 02:42:37 No problem there, right? There are a handful of studies that have looked at this immediately post. And it seems to even augment hypertrophy. So after hypertrophy training, getting in the sauna for 20 minutes? Yeah, whatever, whatever needs to be. We don't have a good titration.
Starting point is 02:42:53 What's the number minutes wise? We don't have a temperature titration. Hot shower would be a second, that would be a week second best. I would say it's a very week. So take a hot bath. I think a hot bath is probably a lot closer to what you're looking for.
Starting point is 02:43:08 It actually kind of goes back to our initial conversations theoretically, you're just going to aid in blood flow. So you're gonna put more nutrients and more waste product out, metabolic stress, all that stuff is going through. So that's the thought anyways, we far from no end. Makes sense.
Starting point is 02:43:23 Plausible, right? Absolutely plausible. I'm something people will do, feels good. Let's say with cold and hot, I want to caution you against a couple of things. This is true across all physiology, but you need to be really careful about moving percentages from molecular to outcome.
Starting point is 02:43:43 Very careful. So for example, it's easy to see a paper that says, okay, we put you in a hot bath or something and we saw growth hormone increase 300%. That is not going to result in 300% increase in muscle size, right? In fact, 300% might result in absolutely no change in a physical size, right?
Starting point is 02:44:03 So the, and the reason I'm saying this is because there's a lot of people in this space that will misapply the mechanisms. And they'll grossly overestimate what these things can do and what they do do because they'll find something like that. I mean, you know, this you've done enough cellular work to in the lab. If I see M-tore doubled, I think shit, it didn't work. I need to see a 10X increase before I know it's even physiologically relevant.
Starting point is 02:44:26 So reading that paper, reading someone's social media posts you're like, wow, it increased M2R38%. I'm like, well, I didn't work. And you're like, wow, that's huge. I'm like, that's not 38% increase in muscle size. So that's a very important point I want to make because I'm going to talk about the benefits here in a second. But I don't want people to be fooled into thinking
Starting point is 02:44:43 that this is some crazy miracle, The same thing with the sauna. In terms of general health, health outcomes, it is a clearly a beneficial thing. This is a really good idea to get hot a lot. It is not a substitute for exercise though. It's a very important distinction. If the, if the options are nothing or sauna, get in the sauna. Really, really good idea. If the exchange is though, I don't need to work out because I did the sauna, bad. This is not a winning solution.
Starting point is 02:45:14 You and I know some maniacs that actually work out in the sauna. Oh, we do. Yeah, kind of not for a while. I don't necessarily recommend that. That actually would probably kill a large number of people, but it can be worked up to it. Certainly. Yeah. So every time I talk about that, I flag that because it's
Starting point is 02:45:33 just too easy to hit that and go, Oh, well, I think Dr. human said, if I just get in the sauna, I don't have to work out. No, no, those words have never come out of my mouth. Definitely not working out in the sauna. If I'm in the sauna, I'm either sitting or I'm lying down and I'm trying to make it through. sauna. If I'm in the sauna, I'm either sitting or I'm lying down, and I'm trying to make it through. I tend to do three 20 minute bouts across the entire week. So I aim for 60 minutes per week of heat exposure.
Starting point is 02:45:53 Which is not a ton. If I said I've never worked out in the sauna. Oh, so you're one of those. Yeah, people will do air squats, they'll bring the airdine bike in there. I look at the sauna as kind of a time to get lazy and sweat. Totally fine.
Starting point is 02:46:09 Going back to your question. So potential to aid plausible aid, we need to see more research on that to really get a, don't I, to put this in practice. I think if you try it, very little harm, I, I struggle to see it downside. If you make sure your hydration is on point, right? Because now you got a factor in the fact you just kicked out two or three pounds. If you're at 200 plus pounds, I assume, or roughly, if you're in the sauna for 20 minutes, I would imagine you can do two, three pounds. Yeah, usually I'm, I'm hover somewhere around like to 25 and I drink, um, I drink at 32 ounce, right, it's water with the electrolyte solution that's pretty high salt afterwards. And sometimes during, yeah, and sometimes after that, if I do it late in the evening, I'll go to sleep and I'll wake up in the middle of the night,
Starting point is 02:46:47 just feeling so parched. It's amazing how much water one loses in the sauna. Like a normal sweat rate for someone to 25, especially, and 20 minutes in a sauna, I would absolutely expect you to do three pounds. Easy, without like, really more, probably even more water. Yeah, you're probably half the water that you need to get. And you mentioned the possible benefits of doing it after strength hypertrophy training,
Starting point is 02:47:09 which make sense for plausible mechanistic reasons on not no official data there yet. What about after endurance training, assuming somebody hydrates well enough and they're not overheated from their endurance work, could also be of benefit. Yeah. Wow. So more and more, what I'm thinking the framework here is in an ideal world, one would train and then do sauna, or heat exposure of some kind, endurance training or strength hypertrophy training
Starting point is 02:47:34 and then do sauna, and then do cold exposure on off days or at least four hours away from any kind of training, or if you had to do it close to train, do it before training. Yeah, I love cold in the morning. We've actually run this experiment on professional athletes when we do enough tracking with things like HRB,
Starting point is 02:47:52 which is a global metric of overall fatigue. Okay, and you've probably talked about that before, but problems with it, but roughly idea of overall fatigue. HRB in general higher the score the better, right? So low HRB is fatigue, right? Well, if you wake up and take your HIV in the morning, and then you get into ice, what's going to happen is you're going to see that number plummet. The second you get out, that's going to fall off the earth. This means roughly you've moved into a sympathetic place.
Starting point is 02:48:21 Surprising, you get in 30 degree water, you're going to go very sympathetic very quickly. However, if you continue to watch your HRV for 30, 60, 90 and up to two to three hours post, you will generally see an improved HRV score relative to where you started. So it's back to this traumatic stressor, right? A really cold, shocking exposure will be a net result of you being more relaxed throughout the day, in general. And we've seen that now very consistently across years with athletes. So I think it's a great way to start your day.
Starting point is 02:48:55 You won't need nearly as much coffee after spending three minutes in 30 degree water. 30 degrees is pretty darn cold. I was in the ocean this morning for about three minutes. It felt I didn't bring a thermometer, but it felt like somewhere in the low 50s. But 15 moving is really cold. Water is moving. That's really cold. That's right. The thermal layer that surrounds you when you sit still in cold water immersion. I'm encouraging people now if they really... I was the joke that people like to look real stoic and tough when they're in there, like they're just grinding through with no pain at all, but the stillness
Starting point is 02:49:27 is actually reducing the stimulus. If they sift around a little bit, you break up that thermal layer, that's where the real action is. We've joked about this for years, like do 50 degrees with a whirlpool jet on, now I'm impressed. Because that is hard. You sit in 35 degrees for three minutes. I guess But with XBT, I've seen I can't even tell you how many hundreds of people from all walks of life on all age that we've been able to get In 30 some degree water for three minutes 50 degrees with a whirlpool going that number gets very small Yeah, if you don't have access to a whirlpool This is this should be reassuring to you can some people say, oh, you oh, I don't have access to ice. And ice can actually get pretty expensive.
Starting point is 02:50:05 You're doing a $50 ice bath every day. So you can fill your bathtub with cool to cold water. Get in, but just make sure that you keep sifting your limbs. And it's chilly. Yeah. And the studies on the very well-established increases in dopamine and epinephrine that occur in cold water exposure, we're actually
Starting point is 02:50:22 done at an hour and 60 degrees Fahrenheit. Yeah. And so you don't necessarily need it ice cold or an ice bath. But immersion is really better than the cold shower. The cold shower is kind of a, it's the, it's kind of the espresso shot version. Yeah. Yeah. Yeah.
Starting point is 02:50:40 You know, that's sort of funny because if you look at most of those initial studies and you think, man, how did they get people to sign up? It's just about 45 minutes in 55 degree water. 55 degrees is cold, even if it's not moving, and they're gonna not spend five minutes in them, they're gonna go an hour. And if you've ever done ice baths at that temperature, you know, like, all right, after a few minutes,
Starting point is 02:50:57 it's not that bad, but man, that's a protocol. Yeah, it's kind of a cold endurance protocol, because one thing to get in for one minute to three minutes and you know you're getting out, you could sing a song, you could do anything to distract yourself, but 45 minutes to an hour is intense. Maybe they, I don't know, I don't think they paid the subjects,
Starting point is 02:51:14 but anyway, that study was done in Europe. I forget where it was done, but anyway, they were hearty subjects. I wanna talk a bit about overtraining and gauging recovery. So there are a couple methods that I've heard about and that I use based on some data that I've seen, but mainly discussions with really informed people like yourself, Brian McKenzie, Kelly Starrett and others. The two that I'm
Starting point is 02:51:42 aware of for gauging recovery of the nervous system and kind of systemic recovery are grip strength, especially grip strength on waking in the morning. And the so-called carbon dioxide tolerance test, the ability to do a long controlled exhale after a few rhythmic deep breaths, which I'm assuming taps into both one's ability to mechanically control the diaphragm, but also how well one is regulating carbon dioxide. First question is, is this stuff fiction fact or a combination of kind of anacdata, as I call it? Are there any peer reviewed published data?
Starting point is 02:52:23 Is your lab working on these things? And am I diluting myself using these tools, or are they useful? It's not fiction at all. There are, like CO2 tolerance, there's less published data. We've run a study in our lab looking at the association between the CO2 tolerance and what we call it, trait and stating ZID. And those are in the publication process
Starting point is 02:52:46 is what I'll say. So you can't really talk about that stuff as you know, and tell it's up, but in general, I'd say, there's a reason I'm still doing it. I'll just leave it at that. Yeah, assuming it's not a clinical trial, I mean, I think sharing preliminary findings as far as we highlight them as preliminary.
Starting point is 02:53:01 Yeah. I'm not a reviewer, but I look forward to reading the paper. Yeah, but as you know, scientific, like you need to be careful about sending telling people results before you've gone through that process. Right, which is why I'm flagging this as these results are not yet peer-reve... passed through the peer review process, so you're hearing about it prior to peer review. Yep. Having said that, there's enough in that field. I'm not the first one into that field, and so I'm very confident that that's a real thing.
Starting point is 02:53:26 I mean, in terms of actual tracking recovery, the big picture is this, when we run through it full analysis, when we have an athlete go through our Obama molecular athlete program, we're gonna run and we're gonna look at three major categories. Okay, category one are what we call visible stressors, and then we have hidden stressors,
Starting point is 02:53:44 and then we have hidden stressors, and then we have recovery capacity. Any time the total stress load outpaces recovery capacity, you're either going backwards in your physical ability or you're reducing adaptability. Now you have levers to pull here. You can reduce stress intake or you can increase recovery capacity, right? What we want in an ideal situation is to be able to implement the most stress possible, because that's the driver of adaptation, recover from that. Now we get the most adaptation. An adaptation being simply a change, whatever change you want it to be. That's our gold standard,
Starting point is 02:54:19 right? It's pie in the eye. Some people have endogenous differences. They just recover better. They don't. They're genetic factors. But let's talk about the ones that are manipulatable. If we go to the stress side of it, you want the throttle to be pushed as far down on the ones you want stress from. And as far off of the ones you don't want stress, so that the adaptation comes in the exact area you want. And you're not burning gas and something you don't care about because you're just, you're
Starting point is 02:54:43 taking that total stress bucket too high, recovery capacity over there. So here's how you can do that. You can run some analytics and measure what we do with everyone through these very comprehensive breakdowns to figure out what's that physiology look like hidden and visible, and then what's the recovery capacity. Once we have that blueprint, we can now figure out
Starting point is 02:55:01 what are the two or three things we need to track that are these indicators of what we call performance anchors. So an anchor is something that kind of drags behind you or below you that slows you down. The analogy being, let's say we're going down one of these amazing canyon roads and I won't say which canyon we're in so you can stay hidden here. And your car is going down at a certain velocity and you want to go faster. Most people's first impulse is to hit the gas, the accelerator. We want to push.
Starting point is 02:55:31 Well, that's fine. But if your foot is on the brake and you push the accelerator, you might go a little bit faster. But number one, you're wasting a lot of literal gas to go a little bit faster. And two, you're burning your engine. You're going to blow. The easier your solution is just take your foot off the brake. You're going to go faster by just stopping yourself.
Starting point is 02:55:51 Then if that's not fast enough, we can hit the accelerator. Everyone wants to just push down, right? More stimulus, more optimization, bing, bing, bing, bing, bing. Our first analytics are where are these performance anchors? What's dragging you back? What's putting down the break? I want to move those two or three things out of the way and now let's see how far you get. Oh, look at that. Your recovery capacity has gone way up. Your adaptations are happening faster now
Starting point is 02:56:16 or we can do more work because you're recovering quicker. So we're trying to figure out in those buckets and we have a whole host of things that we measure, biomarkers and surveys and everything else that we go through to find out what's there. So after we've done that, now we're just going to track a few of these recovery markers along the way to figure out what's globally happening. So that could mean grip strength. I have some folks who we're going to test grip strength daily. Others we're going to look at HRV or combinations.
Starting point is 02:56:42 We may look at performance metrics like a force plate. So you're going to do a vertical jump every single day and we're going to look at HRV or combinations. We may look at performance metrics like a force plate. So you're going to do a vertical jump every single day and we're going to see what that's at. We've used the tap tests before, which is how many times you can tap your fingers as fast as possible. It's a rough indicator of central nervous system. In, in a, say, one minute or so. Exactly. And this is apps you can do on this, like the tap is fingers fast you can. It's going to say, hey, you did 60 taps today and your, your average is 75. I like that because it taps into, huh, no pun intended, into upper motor neuron capacity. Because a lot of things like, like, groups strength, obviously, I have to send the deliberate
Starting point is 02:57:14 signal to my hand to grip, but at some point, the lower motor neurons are going to be taking over the majority of the work. Like, the signal is probably one and done, whereas tapping is going to be repetitive sending of signals from upper motor neurons. So some of the athletes I work with, we track blood every day. We track urine every day. We track ideally a combination of subjective and objective measures. Everything from how did you feel last night to environmental sensors of their bedroom, full PSG is going on, running like actual sleep
Starting point is 02:57:45 diagnostics, not or rain nothing against or, but like full analytics. And some of them, it's as simple as how do you feel today and what was your vertical jump? Right. So we're going to put people in a position to succeed. We're going to figure out what's the lever that they need to pull as well as what's their aptitude, what sport they in, what can we realistically get away with. And some of them will take machines with them and we'll do blood every day and urine and all kinds of stuff. And some of them it's a lot lower.
Starting point is 02:58:09 For myself, I'm not, as I mentioned before, I'm not a big fan of devices. I'm trying to wear the wristwatch. I tend to go off feel, which is not, it's not the ideal objective way to gauge things. But part of my reasoning for this is my colleague from the psychology department, Dr. Aliyah Krum, has done some studies where they've given people,
Starting point is 02:58:32 deliberately given people false feedback about their sleep. So told people you didn't sleep very well or they've told people you slept really well and performance can be driven in the expected direction based on feedback independent of how well people slept or didn't sleep. Now that doesn't mean you can take someone that only slept two hours or was up every 30 seconds
Starting point is 02:58:50 because of happening and tell them they slept great and they're gonna perform great cognitive tasks. But you can't take someone who slept very well, tell them that their recovery quotient wasn't very good and their output is going to be worse. And that's my concern about a lot of devices out there, not to name specific devices, but it's still unclear to the general public what the specific algorithms are to
Starting point is 02:59:10 generate these recovery scores, right? And so many of the things that reportedly track sleep aren't tracking sleep, they're tracking heart rate and breathing, which are correlates of sleep depth, but that's different. And again, I'm not knocking those out. I think the sleep trackers, if nothing else, have provided a forum whereby people are very conscious of getting good sleep. It's sort of like knowing the total clerk can take of your food. People go, wow, I'm actually eating a lot more than I thought. It's collaboration.
Starting point is 02:59:36 Or less in some cases, but often the case is that it's more. So I think for the typical person, I'm wondering whether, like myself, because I'm not a competitive athlete, I'm wondering whether like myself, because I'm not a competitive athlete or certainly not a professional athlete, competitive with myself, I suppose, but no one else. Morning pulse rate, I tend to take when I'm waking.
Starting point is 02:59:57 If I wake out of a really stressful dream, I might relax a little bit and then just take my pulse rate, kind of get a range and see if it's spiking for whatever reason. I don't tend to measure grip strength, although I've heard you can just use a classic scale, old-fashioned scale with the Neonel now old-fashioned,
Starting point is 03:00:11 or some other more technical devices, probably, if there's a low-cost one. Yeah, they're all low-low. And then the carbon dioxide tolerance test. So we haven't really talked about that in specific ways. My understanding of it is it's four deep slow breaths in through the nose, out through the nose, and then a big inhale, as max exhale,
Starting point is 03:00:28 and then time duration of exhale through the nose, and then stopping the stopwatch at the point where lungs are empty, not necessarily as long as one could hold their breath. Did I get that right? Pretty much. Okay, and I guess we should credit you and Brian McKenzie. Yeah, those guys.
Starting point is 03:00:44 Yeah, and the folks under Brian Zambarella for really establishing this as a really good metric. When and how can I use the carbon dioxide tolerance test to gauge recovery upon waking post training session? Yeah. That would be a good time. Number one answer is whatever you do, be consistent. So do it under the, like any good science experiment, do it under the exact same conditions
Starting point is 03:01:11 as you can. That generally means somewhere in the morning, because that's when you're probably going to have the most control, most ability going. So yeah, like you would take any HRV or other metric wake up get in a control get stabilized take your metric Got it gonna be pretty good got it Sodium by car leaking soda Rumor has it and data has it that it can actually be a pretty effective training tool very effective Could you explain a little bit of about how it works and how one might explore using
Starting point is 03:01:46 sodium bicarb to enhance training output in a couple of during contact? Yeah, so there's a handful of these ubiquitously effective supplements for performance. Sodium bicarb and it's one of them. It's a very ingenious idea because it's so simple. Effectively, muscle contraction happens because enzymatic function occurs within a fairly specific pH range. So if it gets extremely acidic, it doesn't like it. And so whether you're running through aerobic glycolysis or anaerobic or anything else,
Starting point is 03:02:17 all of these things require even ATP hydrolysis requires ATPase. And enzyme has to, the enzymes don't function while outside of this fairly special range. So what happens is generally fatigue, the sensations of fatigue are actually caused by some signal that, hey, we're starting to run out of pH. Or we're getting in the wrong range.
Starting point is 03:02:37 You're not out of gas, usually. You're not too low on oxygen. You're not running low on muscle glycogen yet. You're typically gonna see signs or feel signals of fatigue way prior to that, mostly being pH issues. That being said, what if we could regulate pH better? Enter by carbonate, right? So without going too far into metabolism,
Starting point is 03:02:58 effectively, what happens is this, you take an inhale and you're mostly breathing in oxygen, O2. When you exhale, you're breathing out CO2. So the difference is you've gained a carbon somehow. Well, all of your carbohydrates in your body come in the form of long carbon chains. In fact, that's what a carbohydrate means. It is a one carbon molecule that has one water molecule attached to. It's a carbon that has been hydrated. In the case of glucose, blood sugar, that's a six-carbon molecule, right? In terms of fat, which are the only two places
Starting point is 03:03:27 you're gonna get most of your cellular energy, carbohydrates and fat, that is also a big long block and chain of carbons. So whether you're getting your energy from fat or carbohydrate, you're going to split those atoms. So in other words, you've got six carbons attached to each other. And in this part of chemistry, it's exergonic. So when you break that carbon bond, so break
Starting point is 03:03:49 one of those carbons off from the other, that's going to release energy. Just like if you had a pencil in here, and I snapped it, and you go, bang, and pop. I broke the bonds that were connecting that graphite, the next piece of graphite, and that released energy, because I put energy into the system, etc. Okay. As a result, though, we've now had, you know, say five or six carbons chained together, we broke one off the end, which is not how it works, but making the point. And now you have one free-floating carbon. Use that energy release to then go make ATP, to then go make your muscles contract. But now you've got carbon floating around. You can associate free floating carbon with being at a higher acidic level.
Starting point is 03:04:31 It's not gonna happen. The only way that you're gonna go through this process is if your body says, do we have an oxygen molecule available that we can bind this to immediately? Yes, we do. That carbon attaches to that oxygen molecule. You can't just put CO2 in the blood
Starting point is 03:04:43 because of what we just talked about. So you're gonna bind it through this by carbon process. It's gonna go through your blood, it's gonna go into the lungs, it's gonna go back into its carbon dioxide molecule, it's gonna go through the alveoli into the lungs and you're gonna exhale. So you went from carbon to this by carbonate system back into carbon exhale.
Starting point is 03:05:00 So inhale, oh two plants, go to the opposite, by the way. So they're gonna breathe in the CO2. They're gonna cleave off that carbon, stack those carbons together, and that's how they get larger. In your blood, those six carbon chains are called glucose. If we store that in your muscle, we call it glycogen. So we take a bunch of glucose and stack it together. And a plant, we call that starch.
Starting point is 03:05:21 That's the fact that we know what it is, right? So you take a bunch of carbon from the atmosphere, stuck it all together, and that's a starch. If you want to do it in the form of fruit, we take that starch, like from the ground, you put it up through the tree, go all the way up to the top, put it into the flower, break it up into these big, huge chunks of starch into little forms called fructose or glucose.
Starting point is 03:05:41 That's why fruit has fructose in it, and that's why tubers and stuff have starch in them. Basically starch in an animal is like a genus. Okay, all that to say, if that's happening, and we know that a byproduct, specifically, a vaneroleucleicolosis, meaning the breakdown of carbohydrates for fuel, typically in a very fast pace,
Starting point is 03:06:01 with low oxygen availability, the downside of that equation is acid production. We know that that's a problem because I started the conversation off there intentionally. So what if we could reduce the acid buildup? Now, how pH kind of works, I went and kind of double negatives there, right? You know, not too much acid buildup. Then could we prolong and sustain energy in a more effective pace, especially in this anaerobic, interwoven kind of environment. And again, that's important because in those things failure is not a result of running out
Starting point is 03:06:33 of fuel or oxygen. It's a result of fatigue building up way too quickly. Is that also true for resistance training? There is maybe more of the the Cretan phosphate system. That can be an issue. It could simply be an issue of force production. You just don't have enough force. At least you're not out of energy.
Starting point is 03:06:50 You just can't muster enough force. You do enough reps, then it's going to be an issue there. Cretan phosphate would be the big winner depending. So to come back a little bit to the beginning, then I'll, I'm circling this altogether intentionally. All right. Well, the way that we produce energy is going to be in two primary categories, anaerobic and aerobic, aerobic meaning with oxygen and anaerobic meaning without.
Starting point is 03:07:17 In terms of muscle contraction, you're pretty much talking about carbohydrates or fat. Now fat is going to be exclusively aerobic, meaning I'm going to use fat from the entire body roughly equally. So you're doing a sprint up a hill and your hamstrings or your glutes or your quadron fire. You can't you're not just going to use the fat that's directly in those hamstrings. You're going to lose it from the entire body. It has to go through liposis so it's in this stored form an adipose tissue. It's got to get broken down, put into blood. Blood's going to have to go through your body, get taken up into muscle, taken up through muscle into the mitochondria.
Starting point is 03:07:49 Then we're going to have to go through this process called beta oxidation. So remember, carbohydrates and glucose, especially as a six-carbon molecule. Fat, if it's in the form of a tris glyceride, it is a three-carbon glycerol backbone and three, you know, tri 123 fatty acids. Three carbon backbone and those fatty acids are just big long chains of carbon.
Starting point is 03:08:11 That's all it is, right? So we're going to break that thing down, put it in the blood, move it up, move it into our mitochondria, you can't walk those things across the mitochondria while they're too big. So what you have to do is leave them off in the little chunks and it turns out we break them off into two carbon chunks. So we call it beta as in two. Move those in a mitochondria that can go through this little thing called crebs cycle or triaxylic acid cycle. And you kick out a bunch of energy out of that. You had two carbons. So as a result of that process, you're going to generate two carbon dioxide.
Starting point is 03:08:42 But remember, you can only go to that process if oxygen is available because you have to be able to place those carbons onto something or acid gets up way too high too fast. This is one of the reasons why fat is a nice fuel source, but it's very slow. It takes physical time to move from the back of your shoulder and your blood down your hamstring, uptake, uptake, uptake. In addition, it's required oxygen availability.
Starting point is 03:09:05 If you need energy faster, you simply don't have the time to bring in the oxygen, transport it through, go through capillaries, exchange through tissue, etc. Carbohydrate, on the other hand, is going to be stored locally in the exercising muscle cell, and specifically in the cytoplasm. As glycogen. As glycogen in the store there.
Starting point is 03:09:25 So what's going to happen initially, your initial demands for extra fuel are going to come from the glycogen store within the muscle fiber itself. It's just going to break right there. And you're going to be off the races. So you have this six carbon molecule, you're going to break it into two separate three carbon molecules.
Starting point is 03:09:38 Okay, boom, that breaking provides you a tiny bit of energy, very small but some. Now you're going to take those two three carbon molecules and you want to be able to oxidize them because that's your only next step. But in order to do that, you've got to go those into mitochondria. So you've got to break one of those molecules off. So then you'll be back to your two carbon molecule just like you did with fat. That's going to go into mitochondria and then it's going to go to the exact same
Starting point is 03:10:03 Krebs cycle, two carbons, etc. But hold on. If you don't have sufficient oxygen or sufficient mitochondria availability and you're stuck at that two, three carbon place, what do you do? You have problems, right? Now we have to say, okay, wait a minute. We have two, three carbon, and we have a bunch of this acid buildup. Now acid functionally is hydrogen. That's what pH, potential hydrogen is what pH stands for, right? So if hydrogen is building up as a byproduct
Starting point is 03:10:35 of muscular contraction attraction, and then you're having this three carbon molecule, what it can actually do is grab one of those hydrogens, and those three carbon molecules, by the way, are called peruvianator, ProveVac acid, right? If you take a ProveVac acid and you grab a hydrogen, put it on top of it, we now have a different name for it.
Starting point is 03:10:51 It's called hydrogen peroxide, lactate, bingo, right? That's what lactate, a lactic acid is, right? So we've now built that up. So number one reason why lactate's not causing you fatigue is actually preventing it, and that it does a bunch of other really cool stuff. But the point is that system currently lasts so long. That gets overwhelmed very quickly.
Starting point is 03:11:13 What are you going to do with the rest of this hydrogen? Well, if you started off in a normal pH range, you don't have very far to go before you've now gone into that level of too much acidity. If you start off in a more basic, and basic, I don't mean simple, I mean, chemistry, right? And more alkaline. Then that same amount of increase in pH is no longer, now just puts you back in your physiologic array.
Starting point is 03:11:34 So sodium by carbonate, whether it's taken as a cream or a powder or baking soda or anything else, can simply put you in a more alkaline state, even out cutely. So this is something you can take right now before your workout. And you're going to delay what we call delay the progression of fatigue. And how would how would people start to approach this practice?
Starting point is 03:11:53 Yeah, I my understanding is you can do this with common, you know, storebot baking soda. No question. There's always a concern about gastric distress. That it's a very effective laxative. Sometimes in an unwanted laxative effect. But how would one approach this before? Let's say I'm going to, I'm doing the mile repeats. Yep. Exercise. Mile repeats protocol that we talked about earlier. I'm doing that for a few months and now I want to try the sodium bicarb. Yep. Proceed on well hydrated, hopefully I'm well rested. I'm ready to go. When am I going
Starting point is 03:12:29 to drink this sodium bicarb solution? How would I make the solution? Let's say I take 10 ounces of water. How much bicarb do I want to sodium bicarb should I put in there? Can we come up with it? Is it half a teaspoon? Is it a teaspoon? Here's how I'm gonna tell you. You will thank me by starting lower. You can always go more later. So a little pinch. You cannot go backwards.
Starting point is 03:12:51 How about I start with a quarter teaspoon? Fine, honestly half is fine. Half a teaspoon. Totally fine. Disvolve that, slug that down. I read a study recently that showed that people will hit their, the peak benefits of this at different times, but it's somewhere, if memory serves me correctly,
Starting point is 03:13:07 somewhere between 60 and 90 minutes later, so I might wanna drink it on the way to the track. It can, it can be as low as 20. Okay, so maybe as I get to the track and so I'm gonna do some warm up with some walk and jogging. I say 45 minutes. Okay. That's just a very rough standard. But yeah, you're right, it is individualized,
Starting point is 03:13:23 and you probably wanna play with that a little bit, if not just somewhere, and then a road of 20 to an hour. Okay. And then the perceived and real fatigue, if done correctly, the perceived and real fatigue ought to be reduced. Yes. I can do more work without feeling exhausted. Will I feel less of a lactate burn? Done in air quotes for those listening, I realized that's a very crude way to describe a complex physiological process. Fantastic. Can sodium bicarb be used repeatedly for longer duration training? Yep. And if I were going to use it with weight training for whatever reason, maybe I'm doing
Starting point is 03:14:01 circuit type training or I'm doing the superset type strength training that you talked about before, push pull, push pull, which is a little bit more cardiovascularly demanding. Then maybe I'd sip that throughout the workout, make sure there's a bathroom nearby. It sounds like, because I do, I am aware that many people get pretty serious gastric distress. It can happen very quickly.
Starting point is 03:14:18 Okay. Great. Well, it sounds like an amazing training tool. I really appreciate you sharing it, because I think it's one that doesn't get a lot of airtime these days, because it's been around, but sounds like it has some pretty impressive effects. Yeah, you know, it's sort of funny about that is,
Starting point is 03:14:32 I mean, I get it pop culture is what it is, but still to this day, if you want to talk about sort of your most effective general health slash performance implementation, it's the same three to four to five. And it's because it worked really well. Without going into the chemistry of each one in the practice, these ones, because I definitely want to get you back to talk about
Starting point is 03:14:50 diet, nutrition and supplementation. Oh, yeah. At some point, but I think we need a full couple of hours to get that right. Yeah. At least if you as a teaser, would you mind just listing off the other supplements that you have found are very effective for many people? So sodium bicarbibaking soda is one.
Starting point is 03:15:10 What are some of the other ones? Yeah, we'll go kind of reverse order. Beta-aligning is another very classically effective one. Similar idea of sodium bicarbidine. So it's going to, beta-aligning is going to come in. It's going to be converted and stored as what's called karnasine. And the muscle and karnasine is an intracellular buffer. So in other words,
Starting point is 03:15:28 it's just going to delay the buildup of acid. So fatigue blocker, if you will. So very effective, very cheap, very safe, well studied. The top one though of all of them by far, that has an incredibly strong safety profile. It has, it is a cheap, it is a simple form to get, has an important magnitude of effect and is effective across multiple domains
Starting point is 03:15:53 of physical health and performance. And it is because of that, it is my crown jewel. It is, in my opinion, without question, they Michael Jordan of all supplementation. And that's creating monohydrate. It affects so many things. We typically think about it as its muscle stuff, right? You've talked kind of, you quickly were talking about the creatin phosphate system. But we have to realize the mass
Starting point is 03:16:14 majority research on creatin phosphate is not in sport performance and it has not been for 20 years. It's inclinical. And it has everything from effects on the neurological system to there. I've been associations to mental health and depression and to be very clear, I am certainly not saying you can take creatine and cure anything. And I'm not saying it's going to stop you from depression or anything, but I'm saying there's a lot of research in these areas and there's a reason people are doing it. Yeah, I completely agree. And if you're willing, I'd love to have you back for us to do a discussion on
Starting point is 03:16:45 creatine and the brain or creatine in the nervous system. Yeah, that would be a lot of fun. And maybe we can do a kind of a journal club in advance of that. For those that don't know, a journal club is where scientists read a bunch of papers and then argue about them, discuss them and try and extract the kind of agreed upon center of mass, if you will. I think I've long been taking five grams of Crete monohydrate per day for mainly for the cognitive effects. I sense an effect that's obviously anachidate up, but I think there are a lot of data out there as you go. There's enough, you're not crazy.
Starting point is 03:17:19 There's enough there and in fact, there's enough mechanism now to understand the metabolic needs. People think the muscle guy, right? So I'm going to think about the metabolism needed to fuel muscle. But we forget cells, immune cells, red blood cells, nerve cells, astrocytes, brain, all this stuff requires energy and it's all going through metabolism. Super interesting. We will do the deep dive on that soon. I have a final question for you. You're involved in a really interesting, I think, really cutting-edge project that I first learned about from you. I don't know of anyone else doing anything as forward thinking.
Starting point is 03:17:58 And frankly, as relevant to the general population because of my interest in people getting better sleep and learning how to do that avoiding stress and learning how to do that. Tell us a little bit about what I believe is called absolute rest. Right. So this is something that we've been playing with behind the scenes for a long time. And this is typically how high-performance stuff works, right? People want exclusivity and so this has been built. Effectively what happened is a friend of mine, Cody Burkart, I don't know if you know Cody, but a famed down in Texas. Yeah.
Starting point is 03:18:31 NASA. NASA guy, yeah, I do know Cody. Wonderful. Just down the road thinker. Everyone's interested in sleep, right? And for forever, I would say, cover using with athletes, but everything available tells you how you're
Starting point is 03:18:45 sleeping. Nothing can tell you why you're sleeping that way. And so we got together in Boulder and then I met some of his former colleagues, computer science folks, Harvard MD, and some really impressive tech folks. And we were just thinking about an idea and we came up with And we started to realize the problems where we use first principle thinking It's one of my favorite approaches if you've not familiar with that go go go with that like that's just a recipe to solve problems This first principle thinking and we just started to think about like man all the sleep tech is is there It's real. I don't need to convince people that they need sleep
Starting point is 03:19:21 Everyone's done that You need high quality sleep, but how can I provide solutions? And with the people I work with, I can't just tell them your testosterone's down or your sleep's down or recover. I need to be able to be like, this is down and here's why and here's our solution. That's how our high performance world works. So enter absolute rest. This is saying, okay, what are the actual nodes that go into high effective, high quality
Starting point is 03:19:44 sleep? Number one is psychology. So there has to be some sort of screening diagnostic for, are you not sleeping because of simply you can't control yourself? And you've done a wonderful job of giving people tools. Or if you can't quite your mind before sleep do this. If you wake up and you can't go back to sleep here, a bunch of things, right? So we have some screens that we can do and there's some other stuff we can do to analyze.
Starting point is 03:20:04 This is a psychological issue. Let's say it's not. You're on a control and we have different tricks we use and stuff on Gemhack we talk about, but it's not that. Okay, is it physiology, which is no number two? Do we know what your dopamine levels are like? Do we know what your serotonin levels are like? What's melatonin look like? What's this, what's adrenaline? What's cortisol? Cortisol being the primary driver? What is this relationship DHA? Where are these things at? So we're going to measure all that and track that. We're going to measure that during the day, prior to sleep, we're going to measure that next morning and even sometimes throughout sleep. And we're going to figure out as a physiology problem. If it is, then
Starting point is 03:20:39 we have clear corrections. If not, we're going to go on the next step, which is, is this possibly pathology? So you have some sort of sleep disorder. we're going to go on the next step, which is, is this possibly pathology? So you have some sort of sleep disorder. We're going to run full, what's called PSG. So probably synography of full, the exact same stuff you would get in a sleep clinic. It's a sensor that's going to go on measuring EEG and EEOG, and we're going to have muscle activation sensors to see if your legs are moving and everything else is going on. And we're going to get a full diagnostic. And if anyone's ever done this, the amount of sleep issues that are happening in people that they don't even realize
Starting point is 03:21:09 is extraordinarily high. So we're going to figure this out. One very quick example, we just did this with a professional athlete. And he was having like 280 roughly of these episodes per night. And to be categorized as an episode, you have to meet these four specific criteria,
Starting point is 03:21:24 oxygen saturation, ventilation changes, brain changes, etc. and any hit that over 200 times a night. And what this technology allowed us to do is figure out what position did all these things occur in. Well, in his particular case, most of them are happening with Zana's back. And so we bought a very simple, like, pillow, basically, that went on his back, that kept him from sleeping on his back. And we saw an 85% reduction in sleep awakeness issues the very first night. Now we did that testosterone eventually tripled
Starting point is 03:21:54 after three months by just improving sleep and all we did is move him on to his left or right side. So a huge improvement, just by understanding where the problem occurred and why it occurred there. We didn't have to change hardly anything else. He had the basic hygiene stuff down and temperature and all that stuff and he had his chili pad and all that to keep the thing cool. We couldn't fix it years by the way. This took us two years of just trying everything we're like, man, and it was just like, I wish, wish we could get you to sleep
Starting point is 03:22:24 better. And we, I pulled out every trick I knew. And it's just as soon as we built this dinner, I'm like, oh my God, it's all, he's not overweight. By the way, he doesn't have any, he's not ironed or fished and isn't have any of these other clon, classical symptoms that are associated with bad sleep. Sublimatization, everything we've done, a thousand protocols, that fixed it overnight. So if it's not psychology, it's not physiology, and it's not pathology, then the last one that people don't have any idea about is environment. And so what you don't realize is we have a box we can sit right next to your bed, you just plug it in, you don't have to do anything. And it's
Starting point is 03:22:55 going to run full environmental scans. So it's going to look at the temperature in your room, it's going to look at the humidity in your room, it's going to look at the volatile organic acids, these are things that are seeping out from your mattress, it's going to look at particulates in the air and pulse of allergens and things that are floating around that are closing your nose off so you can't sleep at night. And now you're mouth breathing and you've talked a lot. I'm sure on the previous episode about why that's bad.
Starting point is 03:23:16 It's going to look at your CO2 cloud. So we've talked, we've already set this point up, right? You're inhaling O2, but then you're exhaling CO2. Well, during the day and when we're conversing, you have quite a bit of force with that exhalation, right? You're inhaling O2, but then you're exhaling CO2. Well, during the day and when we're conversing, you have quite a bit of force with that exhalation, right? But at night, it's just barely seeping out of your mouth. So what happens is CO2 sends to cloud up and build around your face, and then you end up re-breathing that CO2. And this can cause a large number of sleep problems because you're simply re-reading
Starting point is 03:23:45 in the panic whether you fully awake or just kick out of a sleep stage, the CO2 around your face is a big issue. This stuff has all been known by the way with the astronauts for a very long time. It just hasn't translated into the commercial spaces. Of course, Condor, high performer space. So we can measure that as well and then we can figure out like for the most extreme we can actually come into a bedroom and build an entire sleep optimization setup and control the entire thing. But for most folks the minimum we can do is run full diagnostics and check off is this environmental related is it pathology is there something else. So is this a commercial device that people can eventually access? It is now. So where can people learn more about Absolute Rest? AbsoluteRest.com.
Starting point is 03:24:29 Very cool. And just a very full disclosure, I wasn't aware that you had done this prior to today, you mentioned I was like to ask people, scientists or otherwise, I was like, love to ask, you know, what are you most excited about lately? And this sounds like an amazing technology. And just to be really clear, that's not like something we're working on. That's landed. That's landed.
Starting point is 03:24:48 We're ready to go. Great. Well, and that's one of the things I appreciate about you is that you're willing to sometimes speculate, but you always say it's speculation. But in general, you're, you seem like the kind of guy where if you're going to be public facing about something, if you're going to make a statement, there's got to be quite a bit behind it. You're not going to elude to the in 10 years, we might be able to do this in five years. You're a very data driven kind of guy. Yeah. Well, the people I work with, we need answers.
Starting point is 03:25:12 Right. We don't have that time frame, and we typically have like, hey, we start the season of four weeks. So that's just more about. Well, as I said, I appreciate that about you, but it is, but one of the many things I appreciate, I think the listeners and I can well appreciate on the basis of today's discussion what a enormous wealth of information you are, how clear and, and, potently you communicate that information.
Starting point is 03:25:39 And also how you can take a huge cloud of information and still distill it into protocols that ought to work for 75% of people, 75% of the time, which is an immensely valuable thing to do. So for me and from the listeners, I just want to say thank you so much for taking the several now hours. I lose track of time, which is a good reflex, all good things. Several hours to take a break from teaching, take a break from research, take a break from the other important commitments of your life and really share with us all this incredible information.
Starting point is 03:26:14 I'm so, so grateful. My pleasure, man. I'm glad we finally got to connect. This has been a long time in the making. It has. And I'm going to bring the breathing protocols to my training. I'm going to start doing more of the endurance type and interuotype training. I'm going to start moving when I do heat. I'm going to start moving when I do cold. I might even start throwing some sodium
Starting point is 03:26:34 bicarbon to a very small amount of sodium bicarbon into some water before I train. And listen, Andy, Professor Andy Galpin. Thank you ever so much. My pleasure. Thank you for joining me today for my discussion with Dr. Andy Galpin. If you'd like to learn more about his work and learn further information about exercise science from Dr. Galpin, please find him on Instagram
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Starting point is 03:28:13 Thank you once again for joining me for my discussion with Dr. Andy Galpin, and as always, thank you for your interest in science. you

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