Leap Academy with Ilana Golan - Naveen Jain: Turning Audacious Ideas Into Life-Changing Innovations

Episode Date: December 31, 2024

Naveen Jain believes that no idea is too crazy to pursue. With the right questions and focus, you can turn big ideas into life-changing solutions. After his father's battle with stage 4 pancreatic can...cer, Naveen wondered why early cancer detection wasn’t possible. This led him to apply his 'Why me? Why this? Why now?' framework, sparking innovation in early cancer detection and chronic disease management. In this episode, Naveen talks with Ilana about the mindset that drives him to solve the world’s toughest problems. He emphasizes the importance of staying focused, persistent, overcoming failure, and obsessing over solutions. Naveen Jain is a serial entrepreneur, author, and philanthropist dedicated to solving the world’s biggest challenges through life-changing solutions. Driven by a relentless passion for innovation, he has built several successful companies in diverse fields.  In this episode, Ilana and Naveen will discuss: (00:00) Introduction  (01:29) How Life’s Experiences Shape Who We Are (04:50) The Three Questions You Must Ask Before Starting Any Project (11:20) Overcoming Fear and Embracing ‘Moonshot’ Thinking (13:16) Turning Personal Loss into a Health Revolution (18:33) Why Microbiomes are the Key to Preventing Disease (22:50) Using Cutting-Edge Tech for Early Cancer Detection (30:07) How Obsession, Not Passion Helps Entrepreneurs Succeed (33:00) The Power of Persistence in Overcoming Challenges (39:41) Parenting Future Entrepreneurs (42:41) Teaching Kids to Question Everything and Drive Innovation (50:26) Embracing Crazy Ideas and Never Giving Up (51:34) How Viewing Failure as an Experiment Fuels Growth Naveen Jain is a serial entrepreneur, author, and philanthropist dedicated to solving the world’s biggest challenges with life-changing solutions. Driven by a relentless passion for innovation, he has built several successful companies in diverse fields. He founded Viome, a health-tech company specializing in personalized medicine through microbiome and gene expression analysis. He also co-founded Moon Express, a company focused on mining resources from the Moon. Naveen is the author of Moonshots, and his mission is to help humanity realize its fullest potential on Earth and beyond. Connect with Naveen: Naveen’s Website: https://naveenjain.com/  Naveen’s LinkedIn: linkedin.com/in/naveenjainintelius/  Naveen’s Instagram: www.instagram.com/naveenjainceo  Resources Mentioned: Evvy Website: https://www.evvy.com/  Naveen’s Book, Moonshots: Creating a World of Abundance: https://www.amazon.com/Moonshots-Creating-Abundance-Naveen-Jain/dp/099973640X   Leap Academy: Ready to make the LEAP in your career? There is a NEW way for professionals to Advance Their Careers & Make 5-6 figures of EXTRA INCOME in Record Time. Check out our free training today at leapacademy.com/training

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Starting point is 00:00:00 When times are tough, you give up because you don't think it is worth it. Naveen Jain, a serial entrepreneur, a philanthropist, author of Moonshots and the use formula. Making money is simply a by-product of doing things that improve other people's lives. Your self-worth comes from what you create. If you haven't created anything and you own a lot,
Starting point is 00:00:22 you're still a parasite on humanity. Entrepreneurship simply about solving a problem is not about starting a company. You could be inside a company and be an entrepreneur because you're solving a problem. If you can help a billion people live a better life, you can create a hundred billion dollar company. Non-experts are better at solving the problem
Starting point is 00:00:42 than experts are, and here's why. Making money is like having an orgasm. If you focus on it, you're never going to get it. You just have to learn to enjoy the process. How do you come with these moonshot ideas? You know, there is a method to the madness, and I'll give you the framework for that. Naveen Jain, a serial entrepreneur, a philanthropist. He's the author of Moonshots and the use formula, which we'll talk about.
Starting point is 00:01:20 But Naveen, how the way you grew up shaped you and taught you everything that you know today. It's really the strings of experiences, first of all, that makes you who you are. You know, a lot of us tend to go back and try to find that one single moment that changed us, right? And it comes from this philosophy that we constantly keep saying, it's the last straw that breaks the camel's back. And we all know that it it's the last straw that breaks the camel's back. And we all know that it's never the last straw
Starting point is 00:01:48 that breaks the camel back. It's all the other straws that were there before, right? So it's really the strings of experiences together that makes us who we are. Every experience in childhood that you have, good, bad, how your parents actually nurture you. And then as we get along, I would love to tell you a little bit more about this idea of counterintuitive parenting and how we
Starting point is 00:02:13 incorporate that into our own world. Because, you know, when you are born and when your kids are born, they don't come with a user manual. It's not like, here I am, here's how you operate me, and here is my user manual. Right? I wish. I wish, right? The point is we all wish that way, but that's not how it happens. And we do our best to raise children. But it's really interesting is that if you grow up in humble beginnings like many of us do on who are the first time entrepreneurs, we all grow up in very humble beginnings. And we believe that shapes us who we become because we still have that hunger, that desire
Starting point is 00:02:54 to actually do something. And it could be a desire to obviously be financially successful. But as you will learn, making money is simply a byproduct of doing things that improve other people's lives. And I'll give you how I look at starting every venture. And Ilana, as you know, that I've started many, many companies and knock on plastic or I can't find wood here anymore in the office. Here, I have one for you.
Starting point is 00:03:22 Here you go. So knock on wood, every company so far I've started has been wildly successful. You know, there is a method to the madness of how do you think about these audacious moonshot ideas? And I'll give you the framework for that. And then as we go along and we'll talk about that, now that once you become successful,
Starting point is 00:03:41 how do you start to bring that type of hunger into the children and how would you start to bring that type of hunger into the children and how would you go about doing that? So with that, first of all, I want to thank you, Ilana, for hosting me here. You have been an unbelievable mentor to millions of people who listen to your podcast. And the fact that you're dedicating your life to improving other people's life is something that everyone could learn from. So it's not what I'm going to tell you that is going to be important. It is everyone who is listening to you every single episode.
Starting point is 00:04:18 They need to know that your sincere desire to help the humanity, to help everyone who's listening to it, make them better with every guest. You give your time, the most important thing you have in your life, your time to actually doing it for others, someone else. And that to me is so commendable. So my hats off to you and thank you. That's so beautiful, Naveen. Thank you. That means a lot and it is a big passion. And you've been doing all these things to change millions of lives. So I would love to learn more how you started, what you've done. How do you come with these moonshot ideas? What do you do?
Starting point is 00:05:00 Ilana, so first of all, every time you start any project, you should ask yourself three questions. Why this? Why now? Why me? And I'm going to explain these to you in very simple things, how you go about doing it. So why this is about, go backward and ask yourself, God forbid, I am actually successful in solving the problem that I set out to solve. Would it help a billion people live a better life? It could be 100 million, it could be 10 million, it could be 1 million. Would it help people's life be better? If you can help a billion people live a better life, you can create a hundred billion dollar
Starting point is 00:05:42 company. But you don't wake up in the morning and say, what should I do to create a hundred billion dollar company? Making money is simply a by-product of doing things that improve people's lives. And a lot of young people who just don't seem to understand that concept, so I explained to them in a way they do do, which is making money is like having an orgasm.
Starting point is 00:06:02 If you focus on it, you're never going to get it. You just have to learn to enjoy the process. So every time you start, whatever it is, ask yourself if you're successful, would it actually move the needle? Would it help lots of people live better life? The second part is why now? So why now has actually two pieces to the puzzle.
Starting point is 00:06:21 Number one is ask yourself what had changed in the last two or three years, but more importantly, what do you expect to change in the next three to five years that will allow you to solve the problem at scale in three to five years and this problem could not have been solved five years ago. That means are you actually intercepting and taking advantage of the technologies that are coming up and actually scaling as the technology, the price performance curve is coming down rather than using something
Starting point is 00:06:54 that already existed five years ago, because then you're gonna become commodity by the time you even launch. So really understanding what is changing and how do you intercept these technologies that are happening. So if you look in today's world, the cost of sensors are coming down, they're becoming faster, better, cheaper, right? So you look in the iPhone, number of sensors that are coming out.
Starting point is 00:07:15 You look at AI that has been able to now process this massive amount of data. You look at these cloud computing, that means you can have so much data coming out of the sensors that can be stored and compute at a very minimal cost, and then using AI to actually be able to make sense of it. So what would you do? So now the question is, if you know this is what is going on, what industry would you disrupt?
Starting point is 00:07:41 What is it that you care enough about to do that? So that's number one part. And the second part of the puzzle really is you never ever focus on how you're going to solve the problem. But you want to ask yourself, what are the set of problems that need to be solved for this big problem to be solved? So let's pick any examples, right? So let's say we want to live on Saturn. You don't say, oh, that's not going to happen. Right? You simply say, what would it take for us to be able to live on Saturn? Number one, you have to be able to live Earth orbit. Number two, go from all the way Earth orbit to the Saturn orbit. Number three, land on
Starting point is 00:08:22 Saturn and number four, find a way to actually live on Saturn. So there are four problems need to be solved and suddenly you will realize leaving the Earth orbit we have done that many times we call them a rocket. Right? Going from Earth orbit to Saturn, well we have been to Mars so we know and we have taken horizon that has gone beyond Pluto out of our solar system so we do know how to go long distances. And if you're gonna have people there, maybe we'll have to modify it a bit more
Starting point is 00:08:50 about how we're going to do that. But that's the technology that does exist. In terms of landing on Saturn, well, we don't quite know that, but we do know how to land on Mars. And maybe the gravity on Saturn is slightly less or slightly more, but we landed on the Mars three different ways slightly less or slightly more, but we landed
Starting point is 00:09:05 on the Mars three different ways. We did the bouncing ball, we did the crane, we did the parachute. So we know multiple ways we can actually land on a different planet. And now maybe we have to modify a little bit, but we know it's the incremental problem. And the last thing is, how are we going to go live there? And that really comes down to my last question, which is, why me? This is about the questions you ask is the problem you solve. Why me is really about how are you looking at the problem from a different perspective
Starting point is 00:09:38 than everyone else has been looking in the industry. For example, if you say, I want to solve a world hunger problem or I want to live on Saturn, it's the same thing. When people are talking about every single person who wants to solve a world hunger problem, if you ask an expert, they will tell you it is about increasing the yield of the crop so you have more food for more people. It is about reducing the wastage in the transport because so much of the food that's wasted in the transport. So how do you grow the food closer to where people are?
Starting point is 00:10:10 But no one will ever ask the question, why do we eat food? Because suddenly when you ask question why we eat food and you say, oh, you need energy and you need nutrition. What are the different ways can we get energy? Well, plants get energy from photosynthesis and there are bacteria that grow in the radioactive nuclear waste. They get the energy from radiation and they protect their DNA from radiation. So what if we can take a genetic material from these bacteria, use CRISPR to modify our cells and now we are radiation resistant and we can get energy from radiation and
Starting point is 00:10:47 Suddenly it is like living on set and say honey Do you want to go out and get some radiation not go out get some pizza? Right and you have now opened up the problem to many more solutions that you would have by simply Asking why we eat food not how to grow more food And that's the foundation to solving big problems. So what you're saying, the questions you're asking will actually decide what you are actually focusing on. And that determines basically the levels of solutions that you're starting to look at. One of the things that we notice with a lot of entrepreneurs is even that is scary.
Starting point is 00:11:27 So even asking these moonshot questions, you don't necessarily want to hear the answers because you don't want to take something so big on yourself. So how do you work on the fear? Interesting thing is, it's easier to solve a big problem than to solve a small problem. It's really counterintuitive, really. And here's why. If you have something that is so audacious, the best and the brightest in the world want to work on the toughest problems.
Starting point is 00:11:58 The people who are successful, they want to create legacy. And what they want to work on is something if they are successful Changes how humanity is going to live in the future, right? That means that allows you to get the best and brightest to focus on your problems Number two when you have the team and you have a great moonshot good audacious idea Everyone who wants to invest is to look these guys have an great idea. And look at the kind of people they have assembled, you get the investment. So it is really easier to solve a big problem than to solve a small problem. Imagine if you say, I'm going to develop another iPhone app that will help you find a roommate. People say, good luck, have fun with it.
Starting point is 00:12:39 And when you come back and tell someone, hey, we're going to actually make humanity a multi planetary society. We're going to make illness optional. What if we can actually solve the problem that no one ever have to develop a cancer or have depression or ever have Alzheimer's? People say, sign me up. Tell me how you're going to do that. And suddenly you now have the best in the practice in the world who want to work on
Starting point is 00:13:05 the problem that you set out to do. Let me take this framework and let me apply it to the company that I started because that actually will ground it so you can see how to apply it. Right? So seven years ago, I found myself in a really tough predicament. My dad was diagnosed with stage four pancreatic cancer and there is nothing I could have done. At this point he was given three months to live and unfortunately that's all he got. And it occurred to me that there was nothing, there was no symptom, there is
Starting point is 00:13:38 nothing we could have done. Why in this age we can't find a way to detect early stage cancers? Why is it that we had to wait until he was at stage four and there was nothing that we could have done? I started to think back and looked at his life. He had high blood pressure. He had diabetes. He had all these chronic diseases and we just accepted that's how it is. He's getting older.
Starting point is 00:14:03 Obviously, he's going to have high blood pressure. Of course, he's going to have heart disease. Of course, he's going to have diabetes. Of course, he's going to gain weight. This is all we accepted. And we say, wait a second, why does it have to be this way? Because humans have not changed in the last hundred years as a species, yet younger and younger people are getting more and more chronic diseases. There has to be something we actually have changed So this is how I started I said what if and every moonshot idea every project I do I always start what if what if we can actually understand what changes in the human body at The onset of these chronic diseases, whether it is cancer
Starting point is 00:14:46 or diabetes or heart disease or Alzheimer's. If we can do that, if we understand what is changing in the human body, then we will be able to potentially prevent the disease from happening, diagnose them early, and God forbid outright reverse them. If we can do that, then I ask myself, if I could actually be successful in solving this problem, would it help a billion people live a better life? And the answer was eight billion. Every one of us is going to suffer from it. So I said, good. So why this is checkmarked? Because we know that this is a big problem that we
Starting point is 00:15:18 could attack. And then I asked myself, why now? And we said, look, to solve this problem, there are three things that have to happen. We have to be able to digitize the human body. We have to be able to take massive amount of data that's coming from this digitization and to be able to process the data. And number three, the AI has to be powerful enough to be able to make sense of all this data.
Starting point is 00:15:43 So I said, OK, let's understand what is it that's going on in the industry that will allow us to do so. The cost of sequencing is still $1,000 to understand just the one simple sample. And if you were to sequence this $1,000, and we said that's too high, we can't solve this problem. But it used to be $100,000, $10,000, it is $1,000. In the next three to five years, it will come down to $100 because it costs this plummeting. Guess what? Seven years
Starting point is 00:16:14 later, Ilana, it is now down to almost $5. Right? So think about it for a second. When we were 10 times optimistic, it turns out we were 20 times pessimistic because the costs were plummeting even faster than we imagined. And I will come back and explain when technologies are on exponential curve, our human mind cannot ever fathom how fast they move because human mind is designed to think linearly, whereas these technologies are growing exponentially. And for example, if you are to ask and say, Ilana, you have two options.
Starting point is 00:16:50 I'll give you a hundred million dollars right now, or I can give you $1, but for the next 30 days, I will double every time. So I'll give you $1 today and the $2 tomorrow, and I'm gonna give you four and then the eight. And you do the math and say Eight become sixteen dollar become thirty two dollars sixty four dollars and then with sixty four hundred twenty eight two hundred fifty six dollars 512 dollars and thousand dollars and I'm already at eight days and I'm thinking in 30 days
Starting point is 00:17:17 Never is going to be a million dollars Let alone hundred million dollars give it to me now without realizing that 30 doubling later it is a billion dollars. And that is the part of the thing that human mind just never, because it looks at the early things and it forgets the part. So that was first part was cost of sequencing was coming down. And then we looked at and see to process, we will never have access to supercomputer, but we can use the cloud computing. And we looked at the cost and they said cost was at that time was about $47.
Starting point is 00:17:48 And we say, wow, that's a lot of cost to process a single person's data, but it has come down. Cost of storage is coming down. The cost of CPUs are becoming more faster and cheaper. This should come down to about $10 in the next three to five years. And today we spend about $10 in the next three to five years. And today we spend about $1.50 on that.
Starting point is 00:18:08 And AI, by the way, everyone has realized that AI was going to be more and more powerful and we will have the AI that we needed for doing that. So we realized the time to start was then. Then came the biggest part, why me? And again, I am not a scientist, I am not a doctor. And here is the problem that I'm trying to solve in healthcare, know nothing about it. And most people will be so scared about not knowing anything. People say, you're not a doctor, you're not a scientist,
Starting point is 00:18:35 how are you going to solve it? And I think as I was telling you that non experts are better at solving the problem than experts are and here is why. Every expert takes the foundation to be granted because that's what makes them an expert. The foundation of the industry they take it for granted because the foundational knowledge is what makes them an expert. Non-experts are the only one that can challenge the foundation of everything that experts have taken it for granted. So here I am,
Starting point is 00:19:05 never done healthcare company and my first thing was, wait a second, everyone in the industry is asking, they want to know about your DNA and they were, you know, tens of companies doing DNA testing and everyone thought DNA is unique to every individual. If they could somehow understand the DNA which they understood through the software of our body, if they knew your DNA if they could somehow understand the DNA which they understood the software of our body if they knew your DNA they could find out what is going on. And my first reaction as in non-expert was does your DNA change when you gain 100 pounds? So if you do my DNA test today and I gain 100 pounds has my DNA changed? And the answer is no. Now if I become diabetic has my DNA changed? No. If I have a heart disease my DNA changes? No. I have depression, anxiety,
Starting point is 00:19:50 does my DNA change? The answer is no. And my point was in fact even after you die your DNA doesn't change. So if you were to look at DNA of a dinosaur it's the same DNA. So if DNA can't even tell you you're dead or alive, how will it ever tell you you are becoming healthier or sicker? And that was my first thing was as a non-expert I say, wait a second, DNA is not the place to look for. What changes? And my then back to my Khan Academy, what happens to the DNA?
Starting point is 00:20:18 And we say, well, DNA makes RNA and it's the gene expression or your RNA that's always changing but not your DNA. So your genes don't change but your gene expression is always changing. So what does someone like me say? Let's go measure gene expression. We don't know how to do that. But in my framework, you never focus on how you simply say, okay, so we're going to go measure gene expression. Does that solve the problem? And then as I started digging, it turns out 99% of all the genes that actually are expressed in our body don't come from our mom and dad. They actually come from these microbiome that are in our gut, in our mouth and all over
Starting point is 00:20:58 us. 100 trillion these microbes. So I said, what? So then I start doing the research. So you go to Google research or Google scholar and you see diabetes and microbiome, obesity and microbiome, heart disease and microbiome, Parkinson's and microbiome. It turns out every disease has microbiome that is connected to it. My first reaction was if everyone believes the microbiome is so important and everyone believes the microbiome causes all these disease to happen, then companies probably they're
Starting point is 00:21:31 doing microbiome testing, then why is this problem not getting solved? And then you go back to your first principle. What question are they asking? And it turns out to date, every microbiome company is asking the same wrong question. So every microbiome company is trying to find out what organisms are in Elana's gut, what organisms are in Navin's gut, what organisms are in the gut of people who have Parkinson's or Alzheimer's or diabetes or obesity. And you know my first reaction was organisms are like tiny human beings, just like human beings, they make behave completely differently based on the environment.
Starting point is 00:22:11 So same organism will produce something good in good environment and will produce something bad in the bad environment, just like a human being, you take a human being, put them in a good environment, good behavior, put them in the bad environment, the bad behavior. So what if we focus not on what organisms are there, but we focus on what they are producing, what they are expressing and how it is interacting with the human gene expression. If we can do that, we can solve this problem. That's all why this, why now, why me. So we know now we're going to measure the human gene expression and we're going to focus
Starting point is 00:22:43 on what microbes are expressing and producing and we're going to Look at the interaction of that and that's how we're going to solve the problem now comes the next part How are you going to do this and that's really interesting because I'm just going through the process of how I went through So this is literally took me, you know 30 45 days of just doing the research and say alright So now we know what needs to be done. We just don't know how. So I'm thinking this got to be the really easy thing to do. If I'm thinking about it, somebody's probably done it right.
Starting point is 00:23:12 My first reaction was you're going to think it's really crazy. I thought, you know, NASA JPL is sending these rovers to Mars looking for sign of life. They have to have figured out how you go on to figure out what these organisms are doing so I'm going to go to the NASA JPL I'm gonna talk to the scientists and I'm gonna say hey guys don't you already know how to do this and can I license the technology and they look at me say not really we don't care about what all things are doing we just trying to figure out any sign of life there and I'm thinking bunch of morons if I need to go to NASA Houston the headquarter that's where they got all the good stuff I went there I'm
Starting point is 00:23:47 touching the moon rocks I'm talking to all the scientists but it's still no solution and then I'm start thinking wait a sec I need to start looking at the some of the universities I went to Stanford I went to MIT and I'm now going to Duke and I'm looking at all the universities there's got to be someone who solved this problem it's still I'm out of luck so now I'm looking at all the universities. There's gotta be someone who solved this problem. It's still, I'm out of luck. So now I'm at Lawrence Berkeley, Lawrence Livermore, all these national labs trying to find out what to do. And they're saying, well, we're looking at multiple ways,
Starting point is 00:24:15 but we don't have a solution yet. Then I was at Los Alamos National Lab. And as you recall, the Los Alamos National Lab is famous for what, Alana? What are you famous for? The big atomic bomb. Nuclear, yes. Nuclear bomb, right?
Starting point is 00:24:29 So they developed the nuclear bomb and they were working on their next project, which was- Fascinating story, by the way. Yes, for sure. So they were now working on bio-defense and the biological weapon defense, right? And think about the problem they needed to solve. So they were thinking that if there is a terrorism in our great country, how would we ever protect ourselves? They don't care what organisms are there in the biological bomb.
Starting point is 00:24:55 They need to figure out what they are doing, what they are producing, or what they are expressing so they can create antidote for it. So they spent 10 years developing this technology to figure out how these microbes or these organisms in the biological bomb, what they're going to be expressing, how it's going to interact with the human body so they can protect the citizens. And I'm thinking hallelujah that's exactly what I need. So all I had to do was now get the license to this technology, hired the people who actually worked on the project, and build the company.
Starting point is 00:25:27 And that's literally what I did. So I got the license to the exclusive perpetual license of technology. The person who was working on it, he became my chief science officer. I brought him on board. I hired the head of IBM Watson Research, who was developing all the AI.
Starting point is 00:25:44 I brought him on board and then we started WILE. So think about it, from the concept of simply understanding that why my dad had to die to really going through step by step and looking at this problem and finding what needed to be done and then finding the technology and starting a company. And Ilana, just to complete the story, that is really what warms my heart. Seven years later, we have not only now analyzed close to one million samples. We in fact now, when we analyze your body, we look at your saliva, which is oral microbiome, we look at your stool, your gut microbiome, we look at a fingerprint blood to look at all your mitochondria and the human gene expression in your immune system
Starting point is 00:26:29 so all the cytokines and then we can tell you specifically now don't eat avocado because your uric acid is too high is going to end up causing you gout. Don't eat spinach or almonds right now because your oxalates are not being metabolized. Don't eat broccoli right now because your sulfide production is too high causing a lot of inflammation. But you can eat red meat if you want because your TMA production is very low and your TMA is going to get absorbed in the blood and your liver is not expressing enough of FMO3. That means you're not going to produce TMAO,
Starting point is 00:27:05 which causes the heart disease. You can eat red meat, right? So we can now tell you what foods to eat and why, what foods not to eat and why. And then we say, look, Ilana, you also need more nutrients. You need 22 milligram of lycopene every day. You should take 18 milligram of elderberry every day, take 79 milligram of amylase every day 79 milligram amylase every day and we go through every vitamin
Starting point is 00:27:28 minerals herbs digestive enzyme amino acid we tell you what you need in what quantity and We custom make those capsules for each individual. So just to show you mine. These are mine Notice that it says manufactured on doesn't say expires on every single month. It is custom made just for me. There is no two people get the same formula. Every month I get my probiotics. I get my oral lozenges that are made for me to adjust my oral microbiome. And Ilana, we get personalized toothpaste that are made for me to adjust my oral microbiome. And Ilana, we get personalized toothpaste that are made for you in the morning and evening to adjust my oral microbiome.
Starting point is 00:28:10 And what we did is we published the research that shows people who take the personalized guidance, their diabetes comes down by 30% in three months, blinded placebo-controlled study, fasting insulin down by 25%, depression down by 49%, the IBS which is 15% of the population down by 47%, anxiety down by 42% and we published the research and here is the better part. Now we have a product that can diagnose stage one cancer in your mouth and
Starting point is 00:28:48 throat. And we've got FDA breakthrough device designation. So the whole thing I wanted to do was do this thing so we can collect enough data so we can diagnose the diseases. So today we are the only company that can diagnose stage zero and stage 1 cancer with 95% specificity and 90% sensitivity. So companies like Grail, they do the cancer test, their stage 1 sensitivity is 24.1%. Ours is 90% because we use RNA and not the cell-free DNA. By the way, we can now do the IBD and we are now just doing it for colon polyps, which is 10 years before you develop a colon cancer. So imagine, instead of waiting for cancer to happen, you can diagnose polyps so you can remove them
Starting point is 00:29:32 and never develop a cancer. This is what we set out to do, and now we are able to do that by building a product that consumers benefit today. The data that we collect allows us now to develop early stage diagnostics and soon we'll be able to in fact develop drugs with the pharmaceutical companies to reverse them, right?
Starting point is 00:29:54 This is the mission, just tell you from the idea, the concept to execution, how we did it. And I thought that's a good way of explaining how the framework works. That's so incredible, Naveen. And I think one of the beautiful quotes I think that I heard from you, and I might be butchering it a little bit, but it's something like, what are you willing to die for?
Starting point is 00:30:19 Figure that out and live for that. And I think when you talk about obsession versus passion, can you talk about it? I feel like that is so powerful because you're for that. And I think when you talk about obsession versus passion, can you talk about it? I feel like that is so powerful because you're living that. That's exactly what you're doing. That's exactly the example that you gave. Passion is for hobbies, right? So each one of us, say I'm passionate about this. Passion is for hobbies. Passion is not what moves the humanity forward. You have to have obsession, not obsession for a person, not obsession for things, obsession to solve a problem.
Starting point is 00:30:54 When you find yourself obsessed to solve a problem, that's what it takes for you to dedicate your life. Because nothing that you do in life that's meaningful is not going to be full of hurdles. And when you are obsessed about solving it, you actually are able to find a solution because whether you have to go through the wall, you have to go around the wall, you go under the wall, you go over the wall, it doesn't matter. You're going to solve the problem when you actually care enough.
Starting point is 00:31:24 To me, whether you call that you're not star, this is something you're willing to die for and then you live every minute of your life living for it. This is how you solve the problem. Every entrepreneur, I don't care who they are, whether it is Mark Zuckerberg or whether it's Larry Ellison, they all go through what I call near-death experiences, right? Every company that feels these near-death experiences, and what I realized is that life of an entrepreneur is to feel that they are alive. And the only way you know you're alive is you have a heartbeat.
Starting point is 00:31:58 And what does a heartbeat look like? It goes up and down and up and down. And when it's smooth, you're dead. So anytime an entrepreneur finds themselves living a smooth life, they have chosen to live a life of a dead person. The ups and downs is what tells you that you're still alive. When you are down, all you have to do is hunker down and know the next beat is going to be up.
Starting point is 00:32:24 And here's the lesson of life. When you're on top of that beat, never become too arrogant because always remember the winter is coming and winter shall come. I think Richard Branson has a good quote that I love, the brave don't live forever, but the cowards don't live at all. I went through my own ups and downs. Every single entrepreneur will go through their ups and downs. And sometimes when it catches you at three in the morning and you can't breathe, it is hard. How many people are actually not able to go through these near death experiences, right? And they give up. And I think that's the majority. So how do you maybe you can even share an example of something that was really really hard? And how did you get the power to get back up?
Starting point is 00:33:08 I mean look at Elon Musk He went through this close to bankruptcy for Tesla and he had three rockets that exploded and he had no money left I mean he would have been just completely bankrupt and here he is one of the richest men if not the richest man in the world So what is it? near failure to actually a superb thing because his fundamental belief it is worth doing. Right? When you put everything on the line that it is worth doing, there are people and the universe aligns itself to make it happen for you.
Starting point is 00:33:41 And it's not that somehow I'm talking about some voodoo the universe does. What really happens is when you are laser focused, every single person you meet, you start to think about how can this person help me achieve my mission. Every single conversation is about how will it help me get to my mission. And you start to be so focused that you
Starting point is 00:34:04 are starting to surround yourself with people who believe in you. You start to surround yourself with people who are actually going to believe in you and they help you get to what you want to get done. And you could argue that even from non-scientific perspective, but if you look at that we as humans are made of atoms right what are atoms made of atoms are made of electrons and protons what are they made of quarks what are the quarks made of simple energy so we are nothing but a bundle of energy when we focus our energy on something we resonate at a certain frequency and the other human beings that are also resonating
Starting point is 00:34:46 at a similar frequency, they amplify our frequency and then we align and the people who are negative, they're resonating in a different frequency. Guess what? We don't get to see them and that's the reason people find themselves in a depressed state. They surround themselves with all the people who are depressed. So my point I'm going to make is that this is really the way of knowing that things are going to be tough. And this is the time if you can just hunker down and don't give up on the other side when you come out, that is the bright side of the thing. The day before the breakthrough is the crazy idea. And the
Starting point is 00:35:26 day after the breakthrough, it's an obvious idea. And that literally happens every day in our life. So I always look at every single day, what can I do to move the mission forward? I may not know how far I have to go, but I know the direction I need to go. And as in the Eastern philosophy and the Gita, as they say, my goal in life is simply about action, not the results. Results will come from action. And in Sanskrit, it says, karmaanye vadikaras te ma faleshu kadachan. That means focus your life on taking action and not focus on getting the results. The results are the outcome. And Amazon has a very similar philosophy where Jeff Bezos talks about input and not output.
Starting point is 00:36:11 He said, I wanna know what are you going to do? Why are you going to do it? If you can convince me your inputs are right, I don't care about the output. Whether the output is right or wrong, it's not something you can control, but input is something you can control. It's exactly what we see because people just stop taking action
Starting point is 00:36:29 and then shockingly they don't get the results, right? And we see it a lot, especially when there's fear or regret or rejection or something is taking them down. But what do you do in order to get back up when it's hard and say to yourself, I'm going to take that next step, even if it's scary, even if I don't know what's going to be the outcome, even if I may look like a fool, you still need to take that next step. What are some of the things that you tell yourself?
Starting point is 00:37:00 Is it really just a focus? Is there something that helps you? Are there role models that help you? Talk to me a little bit about. It's not just a focus. It is you care enough. The obsession that I'm talking about, you jump out of the bed at 4 a.m. wanting to solve that problem. You go to bed wanting to solve the problem. When you're taking shower, all you're thinking about how to solve that problem. When you're taking shower, all you're thinking about how to solve that problem.
Starting point is 00:37:25 That is what takes you through the tough times because you know it is worth it. Because remember when times are tough, you give up because you don't think it is worth it. Now imagine if your kids are in danger, what goes through your mind? You become the superman, superwoman, nothing gets in your way. You are willing to take your bare hands and if you have to kill someone with your bare hands, you're willing to do that because your kids are in danger. And that's what I'm talking about. When you have that type of a laser focus and a purpose,
Starting point is 00:37:59 that purpose what drives you. You notice when people, when they find that kids are in danger, the mom becomes a super mom. There's nothing stops them and they have these laser focused eyes and nothing gets in the way. They get that power in their arms that they could probably take down the person of three times their size because you do not want to get in the way of a mom and their kid. That's the power of purpose.
Starting point is 00:38:30 I think with social media and everything that we see on someone else, it all looks easy. So we lose patience, right? We want everything yesterday. We're high achievers. We're driven. But the truth is you're just going to have to take those small imperfect steps every single day to get there. And a lot of these things are a decade long of overnight success, right? So how do you keep the patience? And the way you do that is you take it in a large audacious project and you break them down into smaller milestones. And you start every time you achieve a milestone, you celebrate the milestones. So it starts to look like you're making progress.
Starting point is 00:39:05 So you can't see no progress and keep going down that path. So the thing is, if you say, hey, I'm going to live on Saturn. Oh my God, look at my rocket is now firing the fire. And by the way, I can see the pressure on that is 10 gigabits. Great, love it. And you keep making these milestones to achieve. What are these milestones after milestones that you're achieving?
Starting point is 00:39:28 And that allows you to keep going because now you know you're moving in the right direction. So you wanted to ask something, but I also wanna talk a little bit about moonshots and the use formula. I don't know how you have time to write books, so that's a different story. I was going to actually change the subject on you
Starting point is 00:39:44 and maybe we can talk about you as formula, but I was going to talk about the kids. As I mentioned, the mom and the kids, how does an entrepreneur raise unbelievably great children with the same audacious thinking that they had before they were successful? This is something I always find very fascinating. So we have three children, Elana. My oldest is Angkor, 33 years old. He runs a company called Bilt. And you probably know the Bilt is another unicorn that he started about two years ago. And he went to a Wharton. And my daughter went to Stanford. She's a Stanford Mayfield fellow, and she started a women's health
Starting point is 00:40:26 company called ABVY, which is the best women's health company. And it is another great company that she started. My youngest went to Stanford also, and he's a Schwarzman scholar, and he's a FinTech company that's also a unicorn. So the interesting thing I'm saying, three children, knowing that they are growing up in an affluent family, knowing they don't have to work for a day for living and they decided to take on the audacious projects and take on the challenges knowing that they don't have to do anything. They could live off the wealth that dad created and yet they want to go out and take on some of the biggest project that has never been done and still do that.
Starting point is 00:41:07 So what was that? And this to me is about what I call the counterintuitive parenting. So I'm going to give you five or six tips here because every entrepreneur, that is one of the biggest thing I notice is that if successful person generally will end up having kids who are becoming bums They just don't ever go out and actually have the same hunger same desire to go solve the biggest problems To help the humanity live better So the couple of things number one thing is you need to redefine what success is So we told our children while they were young that your success will never be measured by how much money you have in the bank.
Starting point is 00:41:46 It will always be measured by how many lives you improved. And more importantly, your self-worth will never come from what you own. Your self-worth comes from what you create. And if you haven't created anything and you own a lot, you're still a parasite on humanity. So don't be a parasite. Other lesson that we learned was that as a parent or as a leader, our job is not to take the kids to the water and make them drink. Our job is to make them thirsty. How do you make them thirsty? By giving them intellectual curiosity. Once you give them the intellectual curiosity, that is the thirst
Starting point is 00:42:26 they will rest of their life. They will actually find their own water and they will drink it because they are thirsty. And the thirst comes from this intellectual curiosity that what if that something was possible. And how do you create the intellectual curiosity is learning for them to challenge everything that they take it for granted. Just like I say as a non-expert. Ilana, if your kids were to say, mom, mom, look at such a beautiful blue sky. Normally most parents will say, oh, amazing, you're right. It's such a beautiful blue sky. But your job at that point, what if you were to say, you know,. It's such a beautiful blue sky, but your job at that point What if you were to see you know that sky doesn't really exist
Starting point is 00:43:09 The sky is not a physical thing It is simply a figment of our imagination and by the way that blue color There is no blue color. It is simply the electromagnetic waves that come to our retina they go to our retina. They go to our mind. And we actually interpret these colors. And by the way, the dog may not see the same color. The bat may not see the same color. Other species don't see the same color.
Starting point is 00:43:36 The color doesn't really exist. We create the colors in our own mind. The reason I mention that is not about to teach them about the science. It is about for them to know something they are seeing with their own eyes, something they are absolutely certain about. Even that can be wrong. Everything can be questioned. Everything can be questioned, right? And once you do that, it starts to change their perspective on everything they see in life.
Starting point is 00:44:05 They can say, what if that was wrong? What if we could do it differently? What if that was not true? And that is the intellectual curiosity why kids go out and challenge everything. Just to give you an idea, I still remember during COVID, we were together and said, dad, I want to start this company where people can pay their rent on a credit card and reward them for a rent. And what if there was no charge when you put it the rent on a credit card?
Starting point is 00:44:34 What if there was no charge? And I said, uncle, what are you thinking about? The way credit card company makes money is when you put money, they charge you two and a half percent to the merchant. That's how they make money. But dad, you are the one who told me what if that's not true? What if we can actually convince them that they don't have to make money on that way? And I said uncle you're right. Why don't you go give it a shot? And he literally started this
Starting point is 00:44:57 company based on the thought that what if you don't have to charge on a rent? And MasterCard say, you know what? There are $700 billion in the country that are spent on a rent and we get zero. So we're not going to lose anything and we're going to completely waive the credit card fees for that. And we will charge the money for everything else, but not for it. So that allowed him to rethink that just because that's how it is, doesn't mean that's how it needs to be. The second part really, Ilana, and then I'm going to stop here, would be, you know, our kids were very, very young when I created my first company InfoSpace. The company went on to become a $40 billion company, and our kids were under 10 years old. And the three kids
Starting point is 00:45:40 under 10 years old, most parents would say at that time, oh my God, I've had success now, I'm going to spend time with my young children. Imagine what would have happened if I did that. And if I say, I'm going to spend time with my young children. And most people say, you know, such a great dad who is now quitting everything and spending time with the children. Now imagine what the children see. Children see when they go to school, the dad is sitting on the sofa watching CNBC.
Starting point is 00:46:07 They come back from school, dad is at home watching CNBC and dad tells now, go to your room, work hard, hard work is what it takes. And they're thinking, I want to grow up just like my dad sitting on the sofa watching on CNBC. Instead, this dad starts a second company. He starts a third company. Because dad say money doesn't matter, it's about solving the problems that matter. Dad says, now we're going to go build a company to go to the moon.
Starting point is 00:46:34 And kids say, dad, you're crazy. Nobody has ever done that. It's never gonna happen. Let me show you son how to do that, right? Dad is now turning 60. Dad wants to start a healthcare company. and literally we had a family meeting all the kids are now grown up and said dad you had amazing success you know the health care you're gonna get bloodied you're never going to make it rise into sunset you are high
Starting point is 00:46:58 you got plenty legacy why do you want to destroy your legacy this is not something you want to do and what is this microbiome thing you talk about nobody's gonna give you a poop nobody's gonna know the microbiome I don't know where you learned these microbiome thing you should stop this stuff and I'm thinking oh boy looks like to me I haven't taught you anything yet so let me show you one more time how this is done right and my point is children don't do what you tell them to do. Children do what they see you do. Think about that for a second. Many, many people who are parents, their dad is working at Microsoft or Amazon. Nothing wrong with these companies. They're working
Starting point is 00:47:40 as a mid-level manager or an executive in these companies. And they're saying, why are their kids are not becoming entrepreneurs? I want my kid to be an entrepreneur. And there was a guy who worked for me and said, you know, Naveen, why is it that your kids are all becoming entrepreneurs? My kids refuse to be an entrepreneur. And I said, ask yourself, when you were working on these large companies, you went home, you bitched about your boss, and then you went back to work the next day. What did the kids learn?
Starting point is 00:48:08 Kids learn, I'm going to get a job where I'm going to hit my boss, I'm going to come home, bitch about my boss and go back to work because that's how my dad did it. So point is, if you want your kids to be an entrepreneur, you have to show them what to do and to do it yourself. They learn from you doing it, not from you do and to do it yourself, they learn from you doing it, not from you telling them to do it. So when the kids were young, I won't read them the story. The daily ritual was, I will say, Angkor, tell me a story about a monkey and an ocean
Starting point is 00:48:39 and a palm tree. Your job is to connect the things that are seemingly not connected and he will not tell me stories. Now, I say, dad, now you tell me a story about this, this and this. And the idea we were creating was showing them that everything that looks disconnected can actually be connected together if you think in a different abstract way. When my youngest was applying for Stanford, he said, Dad, I have nothing common, everything I've done.
Starting point is 00:49:06 I've done the neuroscience here, I've done the genetics here, I've done this. How am I going to explain to college application that these things somehow are connected? And I said, go back to what we did when we were telling a story. I said, you talk about how you were intellectually curious and your curiosity drove you to do these things. And the common thread is the curiosity, not what you did. And that's literally what he wrote the college essay, that my intellectual curiosity did not let me focus on just one thing
Starting point is 00:49:37 because I wanted to understand everything before I decide what is it that I wanna do with my life. Oh, I love that. And I think that thread is so important. We would hike when my kids were little. They're still teens, but we would hike for hours and we would just pick some random thing and we would make a whole story on it because we had a long time to drag, right? So I absolutely love this.
Starting point is 00:50:02 Imagination is something that now in the TikTok world, when everything is just coming your way, to be able to step back and actually use curiosity, use questions, use imagination, is just so fundamental. I completely agree with you. Imagination is the only boundary, the only thing that limits us to what we can do is our imagination. If we can imagine it, we can achieve it.
Starting point is 00:50:26 Maybe one last question. If you would go back in time to your younger self, what would be something that you would tell yourself? I was going to say, you're going to probably ask me, what would I change? You know, interesting thing is, first of all, you never ever want to change anything about your past. And here's why. If you love just the way you are, if you changed anything in your past, you will become a completely different person.
Starting point is 00:50:56 Everything that happened is what made you who you are. So fall in love with who you are today, because the day you fall in love with yourself is the day the world will fall in love with who you are today because the day you fall in love with yourself is the day the world will fall in love with you. To answer your question, what would I tell myself if I was young is never let anyone tell you that what you're doing is simply a crazy idea and you should stop doing it. That more people think it's a crazy idea, that's the idea worth pursuing. So dream so big that people think it's crazy and never ever be afraid to fail because you only fail when you give up. And one of the lessons I learned from this is from my daughter, by the way, when she
Starting point is 00:51:38 started Abby, and by the way, anyone who's listening to this, she's go check out Abby.com. This is one of the best women's health company. When she was starting AVI, I said, sweetie, how is the company doing? How is your venture coming along? And she looks at me and said, dad, how little you know about entrepreneurship? And I said, wow, tell me why.
Starting point is 00:51:58 And she says, dad, my job is simply to be experimenting. I am simply experimenting to see what might work. Until I figure that out, there is no company yet. So the entrepreneur's job is to simply experiment and how many experiments you do actually gives the success. This is the idea that I just want to emphasize because this every entrepreneur should know. When something happens, they look at a success or a failure. This is the idea that I just want to emphasize because this every entrepreneur should know.
Starting point is 00:52:25 When something happens, they look at a success or a failure. If you look at that as an experiment, is this experiment has two outcomes, outcome A and outcome B. If outcome A happens, I do this. If outcome B happens, I do this. And if you think of this as an experiment, there is no failure, right? There is no success and B is a failure It is simply two outcomes and each outcome has a different route and as Edison says I did not fail 10,000 times I figured out the
Starting point is 00:52:59 10,000 ways the light bulb doesn't work and that allowed me to find a way that actually works. And that is the power of experimentation, not failure. So you never look at anything as a failure, you look at them as an experiment. And we actually brought a lot of the idea of experimentation from the startup world to the world of careers because I think we never look at the career as an experiment and I don't know why, right? I mean, it just makes so much sense because not everybody's meant for entrepreneurship.
Starting point is 00:53:27 And you know, someday we should really think about what is an entrepreneurship anyway. Entrepreneurship is simply about solving a problem. It's not about starting a company. You could be inside a company and be an entrepreneur because you're solving a problem. So there are three types of people in the world, people who come up with a problem,
Starting point is 00:53:44 people who come up with a solution, and the people who go out and actually solve it. Exactly. I've been watching you, been a big fan, just amazing to see the big audacious ideas that you have and that you're not afraid to go after them, which I think is very, very inspiring for entrepreneurs to see and to realize that, yes, it's really more about taking those steps, taking constant action, not being afraid of failure, because it is about the progress. So I really, really appreciate your coming and sharing all these incredible insights, Naveen. Thank you, Ilan. I really appreciate you, and we'll continue our conversation on the next episode.
Starting point is 00:54:25 Exactly.

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