Modern Wisdom - #993 - Katie Herzog - A Controversial New Cure for Alcohol Dependence
Episode Date: September 13, 2025Katie Herzog is a journalist, podcaster, and writer. Expect to learn why drinking is the route to going sober, why white knuckling alcohol isn’t an option, and much more... Sponsors: See me on t...our in America: https://chriswilliamson.live See discounts for all the products I use and recommend: https://chriswillx.com/deals Get 10% discount on all Gymshark’s products at https://gym.sh/modernwisdom (use code MODERNWISDOM10) Get 15% off any Saily data plan at https://saily.com/modernwisdom Get 35% off your first subscription on the best supplements from Momentous at https://livemomentous.com/modernwisdom Timestamps: (0:00) How Relationships to Alcohol Can Vary (18:36) How Does Alcohol Addiction Manifest in the Brain? (26:58) Building Good Habits to Break Bad Habits (33:53) The History of Addiction Treatment (47:58) Is Medication the Modern Cure for Alcohol Addiction? (01:01:16) Why are Medical Professionals Still Hesitant About Addiction Medication? (01:09:27) Changing Your Relationship to Alcohol (01:22:03) Drinking Cultures are Changing Globally (01:31:53) Find Out More About Katie Extra Stuff: Get my free reading list of 100 books to read before you die: https://chriswillx.com/books Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59 #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp - Get In Touch: Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact - Learn more about your ad choices. Visit megaphone.fm/adchoices
Transcript
Discussion (0)
Talk to me about your relationship with alcohol.
Oh, gosh, it's a complicated question.
So my relationship with alcohol started very young.
I started drinking or I had my first drink when I was in middle school.
I don't know if this is something that 12-year-olds do these days, but back in my day,
12-year-olds drank, or at least they did in my school.
And I loved it.
I loved it from the very beginning, even before I was sort of old enough to appreciate the taste
of a good glass of wine or a cold beer.
I like the effect.
And so I drank in high school.
I drank more in college.
And by the time I was out of college, I was a barfly.
So I spent a lot of time sitting on bar stools from 4 p.m. until late at night,
oftentimes with men who were, because these were the sort of people who would be at bars drinking during the day.
Like men in their 50s and 60s.
These were my people.
And I lived like that for a really long time.
I was a party girl.
So I was a lot of fun back in those days.
I gradually got less fun, the more my drinking accelerated.
By the time I quit, in my late 30s, early 40s, I wasn't a party girl anymore.
Most of my drinking was done solo and in secrets.
But that was it.
And this was not abnormal among my peers and my friends.
My life was lived in bars.
This is what my friends and I did.
And there were, of course, consequences to this.
Some of them pretty terrible.
I went to the hospital a couple times.
I very memorably burned down a porch at one point.
I had trouble.
I see your brow is sort of furrowing here.
Do you want to know how I burned out a porch?
Yes.
So this was actually one of the times when I was, I thought I was being a good girl.
So I stayed home on like a weekday night, which was rare to me at this period of my life.
This was in my mid-20s.
I spent, when I say I was a bar fly, I was at the bar almost every day.
And luckily, this was at a time when Papp's Blue Ribbon was a buck 50, you tipped 50 cents.
So I was not, didn't have, my bar tabs were hefty for the amount of money that I was making, but still, my drinks were cheap.
And so I stayed home one night, thinking I'm doing the right thing.
And I was also a smoker.
And I, ironically, I was, I was watching this, this fantastic television show.
I can't remember what it was called it.
It was about the NY, the New York City Fire Department.
Dennis Leary was in it.
So I was drinking at home by myself, taking regular cigarette breaks and watching this TV show. And on one of my cigarette breaks, I failed to extinguish a cigarette. I just, like, left it burning outside. And I lived in an apartment building. I walked outside. I saw some smoke in like a fairly significant hole in the wall where the vinyl siding had started to melt. I went and got a glass of water first, tried that splash on. It didn't work. Went and got the fire extinguisher. It tried that. That didn't quite.
work. It was still burning. And then I called 911 and they said, you know, this is 911. What's your
emergency? And I said, well, I'm not really sure if this is an emergency. I'm really more looking for
advice. And so I wanted them to reassure me that I don't know what I wanted. I just didn't want to get
in trouble, basically. Eventually they did come and I had to bang on all of my neighbor's doors and
tell them that the apartment building was on fire. And while the fire department was in my house,
dragging a hose through my carpeted living room floor out to the balcony on my bedroom,
I was outside in a patch of woods drinking vodka.
And the next day, all of my friends knew about this.
I lived in a really small town.
I woke up to a friend of mine shouting from outside, what the fuck did you do?
So everybody knew about this.
And frankly, thought it was hilarious, because that's the sort of community that I lived in.
And I thought it was hilarious, too.
I mean, terrible, but also hilarious.
So I had lots of sort of misadventures like that.
I had trouble holding on to jobs. I dropped out of college once. I dropped out of grad school once. I did finish college. I didn't finish grad school. And alcohol just really dominated my life for my teens, 20s, and well into my 30s. And it got gradually, it got less fun and it got kind of more depressing as the sort of friendships evaporated as everybody else kind of got their shit together or didn't get their shit together and died. Frankly, a lot of people I know from those days, from those days are.
dead. And at some point, I realized I was just sort of drinking alone, you know, the last one at
the bar, except the bar, it wasn't a bar. It was my house. And I was by myself scrolling on my phone
during COVID, drinking alone as much as I could. I don't know whether you know, but the first
15 years of my adult life was spent as a club promoter. I ran, I ran nightclubs for a real long time.
We would have gotten along really well in that period. I would have made a lot of money from you.
Yeah. I often think about this that the way that party culture, and I'm not sure if it's the same now,
I genuinely don't know if Gen Z has kind of adopted the louty, Larry drinking culture that I knew and you would have known as well.
I mean, the British, it's kind of a national school for us.
I often do think about how many people were just in the party enjoying themselves, these events that I used to run.
and most people you expected to kind of age out of them to sort of graduate out of the young
party lifestyle but you know I did a million or over a million lifetime entries across my career
as a club promoter so that's a pretty big sample size yeah and I do wonder you know how many of
these people saw the thin end of the wedge which was well this is fun and I'm with my friends
and there's a good DJ on and there's music or this whatever but that that is kind of
this gateway that out the other side of it introduces them to a frequency of use and maybe
not even just alcohol, how many of those people went on to, yeah, kind of be more dependent.
They were, it was 4 a.m. in the nightclub and they were still there, but the club was closed
and no one else was around. Yeah, it's probably not an insignificant number. Not that this is
your fault. People were probably going to find their way to addiction any way they, any, you know,
no matter what happened, whether you had been there or not.
But, you know, you're right in the fact that most people do actually age out of problem drinking.
Most people who binge drink during college don't continue to brins drink into their 40s and 50s.
It's called natural recovery.
This was a concept I was completely unfamiliar with until I started writing my book.
But this concept, natural recovery, this is more common than not.
And most of my peers from my college days did gradually sort of get their shit together.
You know, they got into relationships, they got careers, they had children, and the ability
to be hung over on a Wednesday morning just sort of slowly evaporated, and they shifted as their
lives did. I didn't. I was stuck in that pattern of behavior until well beyond the age when I should
have been. So natural recovery is somebody who drinks heavily when they're younger and then has
their ability to drink and be hung over, gets constrained by real-world responsibilities.
Is that it in a nutshell?
Yeah, that's basically it.
People who, natural recovery is people who don't take any sort of proactive step to recover
from alcohol use disorder.
Alcohol use disorder, you know, what is commonly called alcoholism, is a vast spectrum.
And for a lot of people on that spectrum, they don't have to go talk to a therapist or go
to an AA meeting.
They just naturally age out of it.
And that's the ideal. That's what I wanted. I thought that was my hope. I knew that I was a problem drinker from a very young age. But my hope was that some future me, some older, more mature me, would be able to just sort of, you know, take it or leave it. This doesn't work in my life for my lifestyle anymore. I'm done. It just never happened. I took sort of, it took kind of brew force for me to actually get over my, my habit.
So you knew quite early on that this was a category of drink.
that maybe was even different to some of your friends, that this wasn't just party drinking?
Yeah, I knew from my early 20s. I had my sort of my first come to Jesus moment. I was, I believe,
24, and I was going through my first really serious breakup. And I had, let's just say, I behaved in
some ways that are not optimal to a healthy relationship. I cheated on my girlfriend. And when I was
confronted with that fact when she discovered this, because this was back in the, in the
MySpace days when she read a message that I, that I wrote to a friend of mine, sort of confessing
to my friend of what I had been doing, my girlfriend at the time, she came to the bakery where I
worked. I had a brand new job. I was a barista at a bakery in Portland, Oregon. And she walked in
and she said, you fucking cheat her, and then she slapped me in the face. That was my first
come to Jesus. Then she kicked me out of the house. And so it was like a, you know, like a bad
rom-com where all of my stuff was was out on the on the on the on the on the on the on the on the on the on the on the on the on the on the and that was my first moment of being like oh something is deeply wrong with my behavior and either I'm a bad person either I'm a sociopath or I'm an alcoholic I also for a brief period I convinced myself that it wasn't the problem was in drinking because I didn't want drinking to be the problem because of drinking was the problem that I would convince myself like I convinced myself that I I went to a psychiatrist and he told me I was bipolar not bipolar too which is sort of bipolar light but like
bipolar one. And I was like, hell, yes, that's it. I'm not an alcoholic. My drinking sick. My drinking
actually helps my bipolar. Exactly. I'm not bipolar. I kind of, not that I wish that I was,
but I'm like just sort of fundamentally sort of a low energy person. I'm not bipolar. I was,
you know, I do things like, you know what? It's my astrological sign. I'm a Gemini. That's just
what this is. It turns out I'm not a Gemini. I'm a tourist. And astrology is also bullshit.
but at the time I was sort of looking for any plausible reason that would explain my poor
behavior besides alcoholism. And I lived in, there's this term, I don't remember where I read it,
but this vacillating denial. So at times I was very aware that alcohol was the source of my
problem. And then I would sort of convince myself that it was something else. And I did,
And in one of those moments, I did start going to AA, one of those moments of sort of realization, I did start going to AA. It didn't work for me. But I went to AA at various times over the years. And so I lived like that for about 15 years, about, you know, sort of knowing that drinking was a problem, doing things to try to curb my drinking, quit drinking, moderate my drinking. But ultimately, I was never able to string more than 30 sober days together.
what makes me really it's like an odd irony you having this kind of embarrassing
potentially fatal story where you needy burn down an entire apartment oh that's not what even
one of the embarrassing ones okay well the rabbit hole goes deep i'm excited to learn more
even the point on that is what was the response from all of the people around you and
i did my master's dissertation was on the effectiveness of anti-alcohol advertising
on students at Newcastle University.
And one of the things that I learned when I did that research was
people, especially in the UK, but we can assume in the US as well,
they see those crazy stories as rites of passage.
They're almost like badges of honour that you wear.
And, you know, the movie The Hangover was an entire movie about this.
The whole narrative was you do stuff when you're drunk and lull, that's funny,
because everybody does that stuff
and it's a weird way of
sort of releasing inhibitions
and you're kind of less culpable
for what happens the next day.
We know that that wasn't the real you
but there's this other version of the world
that everybody can kind of step into a little bit
and it was basically that
when you see things as a rite of passage
it's very hard to have interventions
because if you ask somebody
how was your night last night
and they said, dude, it was amazing.
John lost an eye.
Yeah.
you're like. Yeah. That's a good night. Yeah. Yeah. Is that? Because usually, you know, if that was a sports game, that wouldn't usually be there. And it's just a weird upside down sort of topsy-turby world. And I suppose as well, that must allow people who have problem drinking to couch and hide and delude themselves into, well, you know, like, I'm just a fun hang. Yes. Like, I don't have a problem. I'm just a, I'm a vibe. Like, you know, these people are just bores.
Yes. No, that's exactly how I felt. And that was completely normal within my peer group. And the thing that it took me years to realize is that that's not actually normal. It's not. There are many cultures in this world where alcohol is not a regular part of the culture. Talk to Muslims. You know what I mean? Like there are just, you do not have, that does not necessarily have to be a part of your culture. It just was such a part of my culture for my entire young adult and adult life that, yeah, I was, I was so just.
of people who didn't drink or people who didn't drink as much as I drank. Part of that was because
I think psychologically it was a little threatening. Like any time I knew somebody who got sober,
it felt like a betrayal. How could you? How could you do this to me personally? It had anything to do
with me. But it was also just a reminder that there are other ways to live and that life can be actually
better with alcohol, which I genuinely didn't believe. And this is one of the reasons I really
bristled at AA because I would go to AA meetings.
And I would hear these people who, lots of them old timers, who talked about how much better
their lives were sober. And I thought they were lying. I genuinely didn't believe it because I could
not conceptualize that a life without alcohol would be worth living. It was as though I would,
it would be like living without food. How could you do this? I could not conceptualize it because
everybody that I knew drank. And it was such a part of my identity, part of everybody's identity.
It's woven into your lifestyle, right? Beyond just what the drug is doing to you, it's how you bond. It's the place that you hang out. It's the social group that you are around. It's the way that you get a sense of self-worth and that you are a part of a community. It's a ritual that you do to get, you know, it's not just the thing. And the community is such a vital aspect of that. And I think that is, you know, I'm not, I don't drink anymore, but I'm not,
one of these people who thinks the world needs to be teetotal, in some ways, that would probably
be better. But alcohol and community, it is such a bonding experience. I feel that way about
cigarettes, too. Going outside and I think this is, I think the decline of smoking actually has had
some negative effects. And part of that is bonding over a cigarette, going outside and asking
somebody to bum a lighter from somebody. You end up in conversation with people. You know,
the same thing, the rise of the cell phone. And over the last five years, like, if I,
went to a bar in the early days of my drinking, I might bring a book and I would sit there and
read a few pages of the book, but really the book is there as an excuse for somebody to ask
you what you're reading so you can enter into conversation with somebody. If I just wanted to
stay in home and, if I just wanted to read, I'd stay home and read by myself, right?
Phones don't work like that. Nobody looks at you on your cell phone and says, hey, what are you
scrolling? You know, what meme is that? And so there is, there's such a social aspect of that, of that
aspect of American and British culture. And I think it really does add a lot of value to people.
The problem is just that for some people, it doesn't stop there with making friends. It leads to
other things, job loss, health effects, legal problems, death, you know, small things like that.
You talked about multiple rock bottoms throughout your 20s. Yeah. Was there something about a final one
that really propelled you forward, or was it a cumulative thing over time?
Oh, none of the rock bottoms didn't matter at all.
It was really not.
That didn't help.
There was always a lower rock bottom.
And I saw a therapist for a while who said to me, you know, this ends in one of two ways,
or I guess maybe three ways.
It ends in jail.
It ends in death or you recover.
And I thought, well, recovery is clearly the worst option here.
Death is jail.
Jail sounds fine.
I'll just do that.
You know, and I think one thing that's common with a lot of problem drinkers is that you sort of, you almost crave the rock bottom because you think, you know, if I, if I go to the doctor and the doctor tells me, I need a liver transplant and I get one more drink. That's the one's going to come. Then I'll get my shit together. Then I'll quit. I need, I just need one more DUI. One more DUI. And then I'll get my shit together. The problem is even even that level of consequence, people do respond to incentives. But even for me, negative consequences were.
never really able to make me moderate or quit drinking. I just couldn't do it.
What's the lesson that you take away from that? If somebody loves alcohol a lot,
they need to really, really, really, really hate something else way more in order to be able
to compete. And most people that are alcoholics don't hate anything as much as they love
alcohol? No, I don't think it's that. I don't think it's, I mean, alcoholics do love alcohol,
yes. But, like, I know that I love my family and my dog especially more than I love.
love alcohol. I know that cognitively. But no matter how many times I woke up and told myself that
today would be different, today I'm not going to drink, my brain had been hijacked by alcohol.
I felt unable to make rational decisions. You know, I wake up in the morning, today will be
different. I'm not going to drink today. By the time noon rolled around, any sort of willpower,
any desire, my own, you know, sort of rational thinking desire was out the window.
and I was out the door on my way to get alcohol.
I was completely out of control.
I mean, there's a very well-known phrase within AA.
Your life has become unmanageable.
You are powerless over alcohol.
That's, I did not get sober through AA,
but that was absolutely true.
It wasn't because I love Boosmore than my,
I love my wife.
It's because I had no control over it.
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What have you learned about the way that alcohol addiction particularly sort of shows up in the brain,
the mechanism of how this works, the reward signaling, the different types of alcohol use disorder?
What have you learned about this?
Yeah, so I learned a ton about this while I was working on the book. So to simplify things, there are basically two types of problem drinkers of alcoholics. And alcoholic is a term not a lot of people bristle at, but I use it because everybody sort of can, it's easy to conceptualize what an alcoholic is. And again, alcohol use disorder is a vast spectrum. So this could be somebody who just drinks one glass of wine that she doesn't necessarily want or someone who's like fully pickled, pickled her liver. And I was.
like somewhere, not on the middle, somewhere on sort of the far side of that spectrum. Not by any
means the worst, though. So when I drink alcohol, I got a euphoric buzz. It was, for me, it was almost
taking a little bit of caffeine or a little bit of cocaine, right? It didn't make me sleepy. It made me
energized. It may be talkative. It made me, obviously, make poor decisions. Uninhibited, you know,
I'm going to go sing karaoke on a, some, I'm going to go, like, rap. I'm going to go, like, rap.
the water, the TLC song Waterfalls in front of all of my friends and feel great about it.
At one point, now this part is actually embarrassing. I was in a band and my role in the band was
not to sing or to play an instrument. I wore a horsehead mask and I danced around wearing pasties
holding a machine gun. And I did this on stages in front of other people. That's the sort of thing
that I would do when I was drinking, right? So very, very energetic, very much the life of the party,
at least in the earlier days.
In the later days, it was just sort of depressing it alone.
But in my party days, I was very fun.
So for people like me, you get a rush of endorphins when you drink, right?
And that indirectly affects things like dopamine and serotonin.
But you get a high.
For other people, and these people can still have a drinking problem,
but other people get a sedating effect from alcohol.
So they're not getting that big,
rush of endorphins, what they get, it calms them down. For people who drink because they have
severe social anxiety, alcohol can help with things like that. So, and to complicate things
further, some people have, like, elements of both. But so that's one thing that I learned that
alcohol really does have very different effects on different people. So my wife, she does not
have a drinking problem. She drinks, she'll drink a little, like, almost like a shot glass size
glass of like sipping wine while she's cooking dinner, it doesn't make her energize. It's not like
having a little shot of cocaine or red bull for her. It makes her calm. It's a chill thing. It's
sedating. And so for people like her, it's just, I don't think she'll ever have a serious
drinking problem because she doesn't, she doesn't get the really strong effects from alcohol.
She just sort of gets sleepy and slow. Have you got any idea what the difference is between the
you bucket and the her bucket? I'm sure. There's probably,
Probably some biological response to this. And I think this is still sort of an open question. The drug that I took ultimately took, do you want to get into that now?
Let's just round out the rest of this stuff. It's super exciting. I think the process that you went through to get sober is just so fascinating.
Sure. But I would put myself in kind of both categories. I think when I was in my 20s, I was probably more you. And in my 30s, I'm probably more your wife.
Yeah, that's interesting. And there are, so there are particular risk factors for people who develop alcohol use disorder. And one of those is just genes. What is your, you know, is there a history, is there a history of alcoholism in your family? Another one is the age at what you start drinking. And a third and really important one is repeated exposure. Trauma can also be a risk factor. I didn't have any trauma in my background. But those three other risk factors, just.
Genetic history, early exposure, and repeated use, I had all three of those rest factors.
And if I had had two, you know, a genetic history, and I started drinking earlier, but I drank once when I was 12 and I just never did it again, I wouldn't have developed alcoholism, right?
It really was all three. And everybody's different. You know, we make sort of generalizations about this because everybody's different.
And it's hard to make hard and fast rules.
Why do you think the early exposure thing makes a difference? It's just habituation.
It's part of your development?
I don't know.
That's a good question.
Maybe a selection effect that if you start drinking young, that's because you like it in some sort of a way?
That could be part of it.
But, you know, when I was growing up, it was not uncommon for, at least in my sort of, I didn't go to a like a particularly bad Oregon school, sort of a very standard American school.
So I guess I mean sort of bad.
And I wasn't really an outlier within my peer group.
Everybody drank.
And I don't think everybody developed a, you know, an addiction later on.
Yeah, that's interesting.
And I think you make a distinction between relief drinkers and reward.
Reward.
Right, right.
Yeah.
What would you have put yourself into?
Because it seems like, it seems like after a while, anybody that's been a reward drinker ends up becoming a relief drinker, the relief from not being drunk.
Yeah, I think you might be.
you might be on to something there. I was definitely a reward drinker. Even at the end,
I wasn't, for me, it's like the difference between the first drink and the third drink,
I would start to get that euphoria, right, that high. Even though I, even though I knew that I was
going to regret this later on, chasing that buzz became really paramount to sort of everything
that I was doing. I was looking for that. It's not even a long period of time. There was maybe like a 20
minute period between the first drink and the second drink or the second drink and the third
drink, that felt really, really good. And pretty quickly, you know, by the fourth drink and
the fifth drink, that euphoria is gone. I kept drinking in order to chase that buzz, but you
unfortunately cannot recreate it. And then at that point, you know, I would get sort of slower and
sloppy. But yeah, a lot of my drinking was in the effort to capture this one very specific feeling where
I think my endorphins and my dopamine is just raging in my brain.
And that's at the very start.
So, yeah, interestingly, I guess, what is it?
The top 10% of drinkers drink half of the alcohol, something like that.
It's something like that.
It might even be more than half.
It's a massive amount.
So I wonder how many people.
That means that 50% of the consumption is done by 90% of the people,
something in that sort of region, which means that maybe lots of people are able,
to just get that first drink buzz, that one or two drink buzz, and then not continue on.
So it's interesting.
I mean, there was a survey came out recently.
This was either Gallup or Pugh or something like this.
Some survey came out recently that when you look at least, this might be different in the UK.
But Americans, the average American does not actually drink that much, right?
So only about half of Americans drink alcohol, period.
It might be something like 54%.
I'm forgetting the exact number.
And among that 50 something percent, most people drink within the recommended, you know, CDC guidelines, which is a very moderate amount. I think at this point it's like three or four drinks a week for women, maybe seven for men a week. So basically one alcoholic drink a day, no more than three in one sitting ever, things like that. So most people fall into that category. The people with, I mean, one in 10 Americans fall into the category of
of qualifying for alcohol use disorder. So it's still a massive number of people. We're talking
about 30 million people in the United States. But that means nine out of 10 people are basically
fine when it comes to this issue. What did you try? Before the elusive, mysterious strategy
that we're about to talk about, what were the different things that you did before that?
So I did AA. I could never really stick it out. I did individual therapy. I did group therapy. I did
these sort of cognitive behavioral therapy things like moderation management, smart recovery that
have sort of less of a faith-based element. So these are things like tracking your drinks,
just sort of strategies to drink less or to take more control over your alcohol consumption,
drinking a glass of water in between alcoholic drinks. That stuff all went out the window for me
pretty quickly because as soon, like it was on as soon as I had my first drink. Like any pretense
of moderation was just on because, like, that's, I drank to get fucked up. I didn't drink to,
like, enjoy the taste of Papp's Blue Ribbon, you know, the fine effervescence of a shitty
beer was never really my thing. So I did stuff like that. And then I would do these, like,
like I did the master cleanse at one point, which is this idiotic. You, you don't eat solid food for
10 days. You drink cayenne, lemon water. I lasted for like three days. And then I went to the bar.
So I broke my fast with alcohol. I would do stuff like that. You know, I'm going to get really into yoga. That's going to solve my problems. I'm going to, Sam Harris's meditation app is going to save my life. I tried stuff like that. Outpatient therapy. So I like group therapy with other people who had similar problems. That was particularly, I would say, ineffective for me. And a lot of that was also based on principles of CBT.
So going to these therapy sessions and, you know, I have a worksheet and I, like, write down the names of four people I can trust.
And I would write down, like, my mom, my dad, my sister, and my favorite bartender.
So that stuff just, it just never really worked for me.
And a part of that was honestly probably because I didn't take it seriously enough.
But I did, you know, I would show up.
I did try things.
I never did rehab, but I did try lots of other things.
it sounds like white knuckling it with willpower isn't an option then i tried that i tried that
every day it just i'm like a weak-willed motherfucker i just don't i don't i don't i've said this before
but for me you know every day at the gym is day one because there's never a day two i've never
been good at forming healthy habits and quitting bad habits i sucked my thumb until i was nine
Like, I have always had a very sort of addictive, obsessive personality.
And a lot of people who get sober are, this seems particularly true of men, are able to channel that into fitness or adventure sports.
Not me. I wish. I really wish. I think maybe if I had a little, maybe if I start like microdosing testosterone, I'll be like, yes, I'm going to channel all of that energy into doing.
You're going to become an iron man. Yes, yes. I'm not going to become, I might like, you know, watch 11 hours of television in a row. I can, I can bend,
something like that, but I've never been good at sort of
the healthy habits. There is definitely
a sense of the
guys, the sort of classic
mid-30s, mid-40s pivot
toward endurance racing.
Yeah. I think, I mean, it's fantastic
to put your efforts
into something which is great for your health and very
difficult to do and inspiring and all the rest
of it. But I wonder what you're running from.
I wonder what, and that's not everybody,
but it is lots of people.
And I suppose, you know, for me,
I have found a bunch of
different outlets that training has been one of them, meditation's been another. If you don't
have the capacity to sort of build that structure together, then that outlet is entirely precluded to
you. Like that avenue, you don't get to be the guy going and doing an Iron Man. You don't get to
be the person who I'm going to go and do a 10-day silent meditation retreat. My meditation's been
so great recently. I've been really loving it. And that's where I've been putting all of my effort.
And I actually get dopamine and I get reward chemicals from the progress that I'm making in this new avenue here.
I'm going to start new business or I'm going to, you know, whatever, fucking crocheting, you know, whatever you do.
If that's not something that appeals to you because the bad habits are so hard to break and the good ones are so hard to instantiate.
Yeah.
It's making it even more of a headwind to try and sort of fly into to get out of this thing.
Right. And those things, you know, I don't.
have kids. I'm married and have a dog that I'm sort of obsessive about, but I don't have kids. I think for
most people, like, I have the, I'm a podcaster by trade. Like, I would have time to get, like,
deeply obsessed with fitness if I wanted to. I maybe don't have the sort of fortitude to do that.
I think for most people, just live in life, like taking care of your kids, driving your kids to
soccer practice, that shit takes so much time that these sort of other, like having a, having a hobby that you get
deeply obsessed with like maybe during retirement but I think for for the average the average person
is probably just trying to you know kind of get through the day like they don't really have
time for for that kind of thing and alcohol use disorder in that way is kind of a luxury problem to have
well it seems like such a it seems like such a silly way of putting it because it's such it's so
damaging to one's life and it is not as though like there's no need to do a privilege to scramer like
I had the privilege of becoming an alcoholic because we didn't have children.
Because so many people you see who suffer from alcoholism are truly down and out.
Although I think like the stereotypical homeless person, a person living on the street now is probably alcohol might not be.
I think I live outside Seattle, so we see more of like the fentanylene than we do it with like a bottle of wine in this bag these days.
Yeah.
It's unfortunate to think that there is sort of different levels of challenge that people come up against.
How susceptible are you to the substance and then how non-susceptible or limited are you in potential coping strategies or other modes of reward, other avenues that you can go down?
Yeah, and alcohol, it's sort of a rest development in a lot of ways.
So developing those coping strategies, if alcohol is the coping mechanism that you have used from your teen,
age years into adulthood when something goes wrong or something goes right, that's one thing
about getting sober or recovery or even getting control over your drinking. You have to learn
new coping mechanisms. And that can be hard to do when you're in your 40s or 50s and your response
to trauma or tragedy or even, you know, positive news has always been to grab a bottle.
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slash modern wisdom and using the code modern wisdom, a checkout. That's S-A-I-L-Y.com
slash modern wisdom and modern wisdom, a checkout. What does the history of addiction
treatment philosophies look like? From the outside, it seems to me.
me like A.A. was the gold standard. I know that in every TV show that I watch, it's always
that. And the person always usually ends up being okay because the community and their faith
sort of brings them background. But it seems evidently like it's not a panacea for everything.
Right. It's not a panacea for everything. So the history of addiction treatment is pretty
fascinating. So in the early days before programs like AA, and obviously alcohol addiction has,
has, I think, probably existed as long as alcohol is. And the first traces of human consumption
of alcohol was found in some like pottery, some clay urn in China from 9,000 years ago,
some traces of rice wine or something like that. So people have been drinking for a long time,
Right. And you can see in early writings and the archaeological record that there's some, there's some record of not like long-term treatment programs, but like somebody that you would, you could somebody that you could go to dry out, right? And so that that was sort of the, the early days of alcohol treatment were not based on long-term, long-term sobriety or long-term recovery. It was just a place to go to.
to dry out to basically survive withdrawal. So there were, so for instance, the, the guy who
created AA, his name is Bill Wilson, before he created AA, and this is, you know, he wasn't
the first person to start a peer group, but certainly probably the most successful in Western
history, at least. He went to this hospital in New York called, it was called the Towns
Hospital. And he went there four different times. And every time he would go, they would give him
the treatment du jour, which was, it was a, it was belladonna, which is basically a hallucinogen. It's a poison. And they would give, give their patients this and, and, and they would withdraw using this substance. Apparently a pretty, pretty painful, pretty horrible experience. These days, withdrawal can be managed with sedatives and benzodiazepams. And it's not, like, so I thought going, I never done a like formal withdrawal.
before I started writing this book.
And my sense of what withdrawal would be would be painful, right?
You have the DT, the delirium trimmons, the shakes, you're ill, you're sweating on a floor somewhere.
I had to absorb the message of alcohol withdrawal from literature and from pop culture.
These days, it's totally different.
You can go to a center, basically sit in a recliner for a few days and they pump you full of vitamins
and give you some medication and you're fine within a few days.
This can even be done at home as well.
But in the early days, it wasn't like that.
And there were all sorts of sort of maybe not super effective kind of miracle cures that were marketed at the time.
And then Bill Wilson in the 1930s, so this is a guy who'd been a stockbroker, his life had absolutely deteriorated.
And he got, he was at this Charlestown's hospital and he had to sort of come to Jesus moment.
He had a, it might have been a belladone hallucination, but he had this, this moment where he saw a flash of light and he, and he was sort of reborn in that moment as a sober man.
And then at some point, and so he stayed sober for several months. And then at some point within the first, I think, six months, maybe four months, he was on a work trip in Akron, Ohio. And he was fighting the urge to drink. There's, there's this concept called alcohol, excuse me, what's it called? I'm forgetting now.
the alcohol deprivation effect, which you might think that once you go through a period
of abstinence, the desire for alcohol weekends, but that's not actually what happens for a lot of
people. So this concept, the alcohol deprivation effect, basically means that once you go through
a period of abstinence, your cravings can return stronger than ever. And so Bill Wilson was going
through that. And so he had joined what is basically a temperance society. And he called, he called some
like locals that he found through some kind of phone tree thing. And he, and he encountered this man
who was a doctor in Akron, Ohio, his name as Dr. Bob. And they got together and they sat and they
just talked about their problems for six hours. And that was the beginning of Alcoholics Anonymous.
And so they started doing this. They started having meetings of people who had gone through this
experience. And just they would sit in a room and they would talk about it. And they came up with
You know, the 12 steps, the 12 traditions. They added some structure. And one of the early
members of this group was a woman. She was one of the first member, or the first, she was one of
the first female members of AA. Her name was Marty Mann. Good old Dyke. She was a, she was a lesbian,
although I don't know if they used that word at the time. And, and Marty Mann had, she had
spent a lot of time in the UK, she came back, passed out on a stretcher, had to be carried off of
of whatever ship, the Queen Mary, HMS, whatever, whatever, had to be carried off this boat,
came back to the U.S. and continued to drink, right? And so she was killing herself like many
alcoholics do, just suicide attempts, waking up and drinking gin every day, just life deteriorating.
And so her doctor told her that she needed to go to this, go to this Alcoholics Anonymous meeting.
And she was resistant, but she did it. And she said that she found her people. And Marty Mann was
absolutely essential to the spread of the gospel of Alcoholics Anonymous, because she had a
background in PR. She was very well connected. So she used her connections to get A.A. and
Hollywood movies and on the cover of magazines. And she is probably more so than even Bill Wilson or
Dr. Bob, the founders of A.A., for spreading the gospel of A.A. And she also did something else,
which she wanted to lower, lessen this stigma of alcoholism, because alcoholism,
at this point was really considered a moral failing. And so she sort of conceptualized the disease
model of A.A. And a lot of people have, a lot of people assume that A.A. sort of preaches the model
that, preaches the idea that alcoholism is a moral feeling. They actually don't. They really
rely much more heavily on this, this medicalized model. I have my issues with that, with that
sort of framing. I actually don't think that alcoholism is, I don't think it's very helpful
to call it a disease, because it's not like cancer. It's, it's different.
Right. And anyway, so, so she, she spread that message throughout, throughout the land. And that is one of the reasons that AA became as popular as it, as it did, because it had a really good, really good PR team.
Right.
And AA, there were lots of other treatments throughout, throughout history. Things like, there was a clinic called Chic Shadal that did aversion therapy, right? Different, different societies, different cultures. They've, lots of cultures have come up with.
potential solutions to this problem. But AA, at least in the United States, sort of eclipsed all that
for almost 100 years. And now, I think what we're seeing is a broadening of the options, because
AA does work really well for some people. It offers, you know, community, support, accountability,
a place to go, which can be really important if what you do is go to a bar or drink at home,
just getting people out of their, out of their environment is really valuable. And I know many people
whose lives have been saved by AA, but it doesn't work for anyone. I'm sorry, it doesn't work for
everyone. And so what we're seeing now with the rise of groups like Sober Curious and their apps,
there's one called Reframe that I keep getting ads for on Instagram is sort of a broadening.
I think the cultural stranglehold of AA is lessening a little bit. That doesn't mean it still doesn't
exist on some level, like courts can mandate that people who get in trouble with the law go
to AA, professional licensing organizations. If you get, if you're like, I went to meetings not
that long ago where there was a pharmacist there and he wasn't there because he wanted to be
there. He was there because he had a drinking problem and his boss found out and he was going
to lose his pharmacy license if he didn't go to these meetings. Sober houses, they could mandate
attendance in 12-step programs. So for some people who are, you know, who are getting out of jail and
need a place to live and they need to live at a halfway house, they have to enter 12-set programs.
So it is really a mesh within our legal and criminal justice systems, at least in the United States.
I don't know if that's as true in the UK. And it does, to be clear, like, I don't knock it. It really
does work for a lot of people. It just doesn't work for everyone, including me.
That's a long answer to your question. Sorry.
Fascinating. I was thinking about how hilarious it would be if somebody was mandated by a judge that they needed to go and do yoga.
Yeah.
Or, you know, we need to see that you have completed a 30-day streak on Sam Harris's waking up.
Yeah. Equine therapy. You have to go swim a dolphins. Something like that. Whitney Cummings does that. She says it's really good.
I'm sure she does.
So is there a particular taxonomy of drinker that you think A.A.
does and does not work for? Is there something about you, given that it is, for some people,
for many people, a great saving grace, what is it about you that it didn't and what is it
about other people that it does? I think for me it's a couple things. The primary one is that
AA never addressed the root cause of my drinking. And that was that I like to drink, right?
So it's very simple, but I was physically and emotionally addicted to alcohol, and A.A., going to meetings did not curb my cravings. I needed something that would take care of my cravings. And A.A. couldn't do that for me. So I think that is fundamentally it was just that my cravings overrode any sort of desire to quit. I was completely imprisoned by these cravings. I also am not, I'm not a joiner. I'm not.
not predisposed to any sort of club whatsoever.
I also, you know, there's a spiritual element of AA that I found to be a turnoff.
I did go to, they have meetings for atheists and agnostics.
I like those.
I found them a little self-righteous in a way that I really appreciated.
But it just didn't stick with me.
And also, you know, there's a level of when you work the steps.
there's a level of introspection that is required.
I don't like introspection.
Just to be frank with you,
I'm like the one lesbian who doesn't like to process in this world.
I don't like to talk about my,
this is why doing these interviews and writing this book was very off-brand.
You really chose a difficult thing to be talking about for the next couple of years.
I did.
I absolutely did.
I don't like emotional chow-chow.
I find it to be like very, like, uncomfortable.
And so anything where I was sort of expected to take like a searing look into my soul,
I don't believe in the soul.
I believe that I had a drinking problem.
I was physically and mentally addicted to alcohol and I just needed to solve that problem.
But for a lot of people, that is exactly what they need.
And I think that's especially true of people who have done sort of more damage than I have.
I did damage.
I hurt other people for sure.
But I wasn't, you know, I'm not a parent.
I didn't destroy my family.
I didn't, I don't think I, there are probably some people who think I should make amends to them.
They're going to be waiting for a while.
Not because I don't think that's important.
I do think it's important for some people, but my way of making amends is to basically remove myself from people's lives.
So if I have hurt somebody, my punishment is that I no longer...
deserve to their presence in my life, right?
That's my way of making amends.
Yeah, I just, I think, like, some combination of my personality.
I'm a skeptic by nature.
I'm the type of person who would, like, go into an AA meeting and be, like,
Googling recidivism statistics during the meeting.
I just, I'm the sort of person AA was never going to work for it.
Highly non-hypnotizable in that regard.
I listen to your show on hypnotism, and I also want to get my genome map.
I fear that we are both built from the same sort of building blocks there.
I think you touch on something that's really interesting,
which is most people, when they think about a person who's going to go and attend AA,
is, well, this person knows that their drinking is bad,
but it's just out of their control.
And it's destitute and the despondent and they don't enjoy it.
but they're gripped by this sort of evil thing and it's at the bottom of a bottle.
And then there's other people who go, I think drinking's pretty awesome.
It makes me feel pretty good.
And I need to quit but don't want to stop.
Yes.
That's the fundamental problem.
That's the paradox.
I need to quit, but I don't want to stop.
I love this thing, but I hate this thing.
I think that's the, you've captured the inner monologue of many an alcoholic.
Okay. If AA were invented today with all of the evidence that we know about now and it didn't have the stranglehold, do you think that meds would be its first step?
That's a very good question. I think that if Bill Wilson himself founded it, I think yes. So Bill Wilson was extremely open-minded. In the 1950s, he experimented with psychedelics. And this was very controversial within a.
AA because the ethos of AA has always been sobriety, full sobriety, and how can you be sober if
you're doing psychedelics? And he sort of lost that battle. But he was extremely open-minded. And my book
starts with a quote from the big book, which is the Bible of AA. It's the sort of the big text
that everybody reads and studies. And the quote, I'm going to, I'm going to butcher it, but it's
something like someday science might find a cure for the alcoholic, but that hasn't happened yet. And
the thing it, so that was written in the 1930s, I think that science has actually found a cure.
Or at least for some people, I need to couch that in many ifs.
But I think for some people, there's a cure.
And it worked for me.
Take it away.
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Okay, so the crazy thing is that this is not futuristic.
it's non-experimental. So there is a drug, an opioid blocker that was first synthesized in
1963 by a company called Endo Laboratory. So we are talking about, this is, you know,
before the Civil Rights Act, this is, this is old shit. And this drug, it was owned by DuPoint
for a long time. They bought the first laboratory that synthesized this, endo laboratories.
And it's an opioid antagonist, so an opioid blocker. It was initially developed to
treat opioid addiction, which at the time would have been like morphine and heroin, less
fentanyl and oxy and whatever they're selling on the streets these days. And, but it also works
for alcohol use disorder. And it works like this. So because it's an opioid blocker, I'll just,
I'll explain how it works with alcohol specifically. So you take the drug and it blocks the,
your receptors from getting an endorphin rush from alcohol. So it's pretty simple. The molecules
sit on your opioid receptors and they prevent you from getting that euphoric high that we talked about
earlier when you drink alcohol. Now, there are different ways to take naltrexone. The way that is most
commonly prescribed is not the way that I did it. So the way it's most commonly prescribed is for
people to take it every day, whether or not they plan on drinking. So you wake up in the morning
and you take this drug and it curbs your cravings. And for some people, that works. There's also a
long acting form called Vivitrol. So it's a shot in the butt. It's in you for 30 days. It
releases slowly over time. Oh, and I should say this has been FDA approved for the treatment of
alcohol use disorder since 1994. So this is not actually a new treatment. This is an old treatment.
the way that I took it was developed by a man called John David Sinclair. He was an American researcher who did most of his work. He went to grad school in the U.S., did his Ph.D. here, but then he moved to Finland, and he worked for Alco Laboratories, which was a state-owned, sort of an interesting company, especially from an American perspective. So it was a liquor distributor that also had a lap. So taxpayer funded, or funded by,
I presumably, I don't know what the liquor taxes were in Finland in the 1970s, but on the bottom floors of this company, they would be selling and distributing alcohol and figuring out how to get more people to drink.
And on the top floors, where the lab was, or maybe it was vice versa.
Maybe they put the, maybe they put the researchers in the basement.
I don't quite remember at the moment.
You had people like John Davis-Sinclair who were working on treatments for alcohol use disorder.
And John Davis-Sinclair, so he did most of his research.
on mice. And he realized at one point that he was one of the first people described the alcohol
deprivation effect that I mentioned earlier, where after a period of abstinence, your cravings
come back stronger than ever. And he wanted to interrupt that process. So he started out by giving
lab rats, various drugs, including this opioid blocker naltrexone. And then he would give them
access to alcohol. And what he found was that these lab rats,
whose opioid receptors were blocked because of this drug, they would over time, and these were a, this was a breed of lab rat that had been, and it had been bred specifically to have a propensity for alcohol addiction. They were bred to like alcohol, which is actually sort of hard to do. Rats don't and mice don't typically. Like, they're not boozers naturally. But so these ones had been specifically, not GMO, but, you know, good old fashion. You take two rats that, like,
likes to drinks. Yeah, you make them fuck. So you find the ones that are hanging out the bar late at night, get them together, put them in a room together. And so he started these experiments. And what he found was that, yes, these lab rats that, whose opioid receptors were blocked when given alcohol, they would refuse it. They no longer had any interest in drinking. And this effect lasted over time. And then he started writing about this. This was later.
later started doing human studies. And he developed what is now called the Sinclair method. And so
the Sinclair method is very simple. You take an opioid blocker, usually naltrexone. And there are other
ones. There's one called nalphamine that's more common in Europe than it is in the U.S.
You wait an hour, which is how long it takes for this drug to metabolize in your system.
And then you drink as normal. And so that's what I did. I found out about this from an
article in the Atlantic. And during COVID, my drinking accelerated to the point where it was becoming
very problematic. My wife is a nurse. So she was, you know, a essential worker, as we called them
back then, when we cared about them. And she was gone a lot. So I used my recreational time. I had
been laid off from my job. I was a reporter for the stranger, which was an alt-weekly in Seattle.
And when I got out for my job, I did what everyone else did. I started a podcast and I stayed home and I drank by myself. And I did this for two years. I drank basically every time my wife left the house for two years. I didn't tell anybody. I didn't tell her. She had no idea. And then it got to the point where I knew this was I either had to come clean and confess and tell her and maybe go to rehab and probably go to AA and I didn't want to do that or I had to solve this problem on my own. And I had read about the same.
in the Atlantic in an article from several years before. And I decided to do it. And I did it.
And it worked. That's crazy. I mean, we're still married, by the way. She's going to be real
shocked when she finds out about this book. I was going to say, yeah. What was the, what was the
reveal like when you presumably have that conversation and how much of it was propelled by the
potential book coming up? None of it. I had not written the book by the time I told her. So I, so to like,
cut a long story short, I did this for about seven months. I was very regimented about it. I
planned my drinking days. I always took my pill. There was a small handful of occasions when I
skipped it for whatever reason. But for the most part, I was very regimented about this.
And this is one of the things about this treatment. You can't half-ass this. It's like AA in that
respect. Like you got to go, you got to 100% commit because if you don't take the pill and you drink
without your opioid receptors being blocked.
The Sinclair method is basically a process of unlearning a behavior.
It's called extinction or pharmacological extinction because there's a medication involved.
And so if you drink without the drug and you get that endorphin dump and that dopamine rash.
You've done everything that you've just learned.
It's not going to be undone overnight.
But if you do this, if you don't really stick to the protocol,
or if you don't wait the full hour for it to metabolize, it's just not going to work.
It's going to confuse your brain, and your brain will continue to seek out that high.
What you're trying to do is to give your brain the message that that high no longer exists.
You no longer get pleasure from alcohol, and over time, your brain will stop craving it.
And for me, that took about seven months of, like, actively doing the Sinclair method.
And over time, I started, you have to incorporate sort of habit change and mindfulness, which is not natural for me.
not a mindful person. But you have to do these sort of, you have to make some changes in your
life. It's not as simple as just taking the pill and drinking. It's pretty simple, but it's not
that simple. And over time, I started like, you know, pushing my drinking, my drinking start time
back. So instead of starting to drink at noon, maybe I'd start at two or maybe three. And I started
incorporating more alcohol-free days into my week. And alcohol-free days are exactly what they sound like.
So that's days when you're not drinking and you're not taking the pill.
And that's what's different about the Sinclair method than sort of the daily use of this drug,
taking it every morning or the shot, Vivitrol, which is in your body for a month.
You only take it when you're drinking.
And on the days when you're not drinking, you don't take it because you want your endorphin receptors to be keyed up.
And on those days, you go out and you do things that are going to spur a sort of natural high.
You know, go for a hike, have good conversation.
eat good meals, get late if you can. You know, you just, you try to, try to retrain your brain into
seeking pleasure elsewhere because you're no longer getting it from alcohol. So I did this for
about seven months. And then I decided to try for an alcohol-free month. And it was easy. And this
had never been easy for me before, but it was, it was uncomplicated. And after that month,
I just never started drinking again. And it's been three years since then. And I,
And I didn't tell my wife. I didn't tell her. I waited an extra. I wanted to like get a year of sobriety under my belt before I told her. And then a year came and went. And honestly, I had stopped thinking about drinking. Like I think about drinking now because I'm promoting this book. I wrote the book. It's more a part of my life. But for that period of time between quitting drinking, between my last drink and deciding I was going to write this book, I just didn't think about alcohol.
And that's what I wanted because, you know, everybody sort of knows about the physical effects
of alcohol, right? The headaches, the hangovers, the shakes. But for me, the killer was
mental because alcohol was on my mind 100% of the time for most of my adult life, right? And for people
who haven't experienced addiction, I think the best way to sort of explain it is like, when
you have a crush on somebody or you're newly in love with somebody and you all you think about is that person like you're going to work you're having conversations with your hopefully not with your spouse but you know you're like everything in your mind is focused on this desire that's what addiction was like for me so i thought about it i spent 20 years of my life thinking about i still managed to you know have a career in a life and relationships but i spent 20 years of my life thinking about alcohol
almost every moment of the day. It was in the back of my mind. And the Sinclair method and this drug freed me from that. So I basically stopped thinking about it. And then I told my wife after it was more than a year. I think it was like a year and a half after I told her. She was surprised for sure. But not mad. I, like, married well above my weight, both physically and morally. And so we're still married. My wife was like sad for me that I'd gone through this thing. But she was also.
I think, impressed that I had solved. I had a problem and I fixed it on my own. And I would never
advise people to be like, do this without social support. Because in everything that you do,
social support is going to make it easier. But I, you know, didn't do that.
The lone skeptic, again, as is on brand. Yeah. I mean, I did talk to people because I was,
I was also doing a lot of research about this. And so I'm a journalist. And so I would, when I had
questions I would call people. And there's a robust online community. That's sort of one of the
ironies about the Sinclair method is that this is one of those cases. And there aren't many of these
where you can get better information typically from like Facebook groups and Reddit and YouTube
than you can from your own GP. So I was involved in these online communities and having
conversations about it and interviewing people, but I wasn't talking about it with the people who
mean most of my life.
Why is it that doctors are still hesitant to prescribe daltrexone or talk about it or educate about it,
even if it's got strong evidence?
So there's lots of answers to that question.
The first answer, I think, goes back to medical education.
So I don't know how it is in the UK, but in the U.S., historically, addiction medicine has been a very, very small part of medical education.
So I talked to doctors who are, you know, in their 40s and 50s, who did four years of medical school, then four years of residency, maybe did some extra training. Now they're GPs, their family doctors, or they work in an ER. So they're seeing people every day who suffer from some kind of substance abuse disorder, whether that's alcohol or anything else. And they're in that, you know, eight years of medical training and education, the entirety of their training on a
was maybe one hour. Maybe they were told to attend an AA meeting. So historically, it has just
not been a part of medical education in the U.S. This is changing. So there are currently three
drugs that are FDA approved to treat alcohol use disorder. Naltrexone is one of them. There's also
an abuse, which has been around since the 1950s or been FDA approved for the 1950s. And there's
one called a campersate. And there's also various off-label drug, other drugs that are used in an
off-label basis. Now every med student who goes through a psych rotation is going to get education
on at least those three drugs. So this is changing and it's changing really rapidly. Part of this
has to do with the opioid crisis, I think. So for a long time within the recovery industry,
the idea of harm reduction was sort of anathema. You know,
Nobody, not nobody, but a lot of, a lot of these institutions were based on 12-step
programs, 12-strip principles. And in 12-set principles, like, you don't tell people to go
take Suboxone or methadone. You tell them to seek help from, you know, to confess their, to
admit that they're powerless, to go to meetings every day and sort of will their way through
it. But that doesn't work very well for opioid addiction. And so,
So there has been a shift in recent years towards principles of harm reduction and medication
assisted therapy.
So that's part of it.
Just straight up, doctors are not educated.
The Sinclair method has an added barrier to uptake, which is that it requires drinking.
So Naltrexone doesn't require drinking, and lots of doctors prescribe it, take it daily,
and don't drink with it.
But the Sinclair method gives people permission to drink.
And that's going to be a tough sell for a lot of doctors, not just because, right, and for families. And, you know, this, it sounds like it's going to do what? Right. You're going to, you're telling me I can cure diabetes with donuts. Like it sounds crazy. I understand that. There's also legal reasons, right? So if you're a doctor and your patient comes to you and says I'm having a drinking problem and you say, okay, here's a deal, take this drug and then go get a six pack of beer, enjoy yourself. And your patient does that and goes and goes and kill.
someone in their car, you don't want to be legally liable for that. So there are all sorts of barriers
specifically to the Sinclair method that prevent this from being better known. Nowtrecht,
there's also economic factors here, right? So Naltrexone is a cheap generic drug. It's been cheap and
generic for a long time. And no drug company is going to pay to market it because they could
just be undercut by the drug company down the street. So there are several factors here.
Another one, another theory, there's a guy named Percy Menzies. He was a drug rep for DuPont. And so he was one of the, one of the, this is back in this, in the, in the 80s, he was one of the first people trying to sell this drug to doctors, or I don't know if, I don't know if drug's like that term, but trying to get doctors to adopt this drug for use of, um, and of treating heroin addiction. And Percy found when he would go talk to doctors that they were completely uninterested.
in it because at that point,
methadone had sort of
cornered the market. They thought that they had this
gold standard and they weren't interested in anything else.
The other thing is,
this is an opioid antagonist. It has
the word opioid in it. And so
Percy thinks that doctors could be
just straight up turned off by that, because
it's not an opioid.
It's an opioid blocker, but it sort of
emotionally feels like you are giving
opioids to your patients.
It's no one, you know, you know,
opioids are sort of a, they're on the outs these days.
Yes, yeah. It's poor branding right now, I would say, to try and get that done. It's so, it feels to me like the whole kind of alcoholic alcohol use disorder world has been over-moralized and undemedicalized. I think that that's kind of how it feels.
I think you're completely right about that. It's sort of ironic because, you know, a lot of people will say,
asked, they'll say, yes, alcoholism is a disease, but it's not a disease that we typically
treat with medications. And again, I sort of, I have complicated feelings about that framing. I don't
think it's particularly helpful.
There's one who's unsure that it is a disease, but something that you should treat with medications.
Right, right. And now trachshone doesn't work for everyone. I want to be really clear with
this. So earlier we talked about those two types of drinkers, right, reward drinkers and
relief drinkers. And this information, I learned this all from a guy named Joe Vopachelli. He's
He's this fantastic clinician and researcher out of Penn.
And Joe's studies, he's been working with altrexone for decades.
And some of his early studies were used for the FDA approval of this drug.
And Joe explained this to me.
For reward drinkers, this is typical, this people like this tend to be binge drinkers, right?
The people who are going out, going to clubs, dancing in the town fountain, whatever, people
who get energized from alcohol, naltrexone, can work really, really well. It's almost a, he actually
used the term miracle pill, which is not something, this is like a, you know, this is a, this is a, this is a real
doctor here. This is not a term that doctors typically use. It can almost be a miracle pill for,
or a miracle cure for that population. For the other types of drinkers, relief drinkers,
people who get the sedating effect, it has almost no effect.
Why?
I think it's, okay, so part of this, this is like sort of an open question, but the theories that I read and I heard from researchers is that it has something to do with one particular allele. So one particular gene variance. It's called AFS-40, ASP-40, and the MU opioid receptor.
So having that, possessing that allele does not guarantee that Naltrexone will work.
for you, but it's a strong indicator that it may work. If you don't have that, have that
allele. It's a strong predictor that it will not work. Right. Okay. And that that will
tend you toward a particular type of alcohol use and a particular type of response to alcohol
too. That is the theory. Yes. Right. That's interesting. I've just checked. I checked your
genetic and lab reports. The ASP 40 variant your ask for refers to
the O-P-R-M-1 and A-11-8-G polymorphism.
Looking through your genetic report, you do not have the AS-40.
Your O-P-R-M-1 result shows the AA genotype,
AS-N-40, meaning you do not carry it.
So no, so I would be useless.
You might not, it would be interesting to, do you drink now?
No.
It was an interesting journey, I guess, with regards to alcohol for me.
I never had a problem with it in terms of a dependency.
see. But I was a party drinker.
You know, every two weeks I would send it in club promoter fashion.
And then it got toward the end of my 20s.
So what we're talking about now, 28, I think 27, 28 would have been the first time I did it.
So maybe nine years ago.
And I know that low and no movements are kind of all the rage and morning ice plunge parties
and run clubs and stuff are kind of everywhere.
Ten years ago, nine years ago, that really was not the.
case at all. It was not trendy to be against the grain with regards to even social drinking.
And there was just some inclination that I had that alcohol was holding me back. Even though I wasn't
using it that frequently, I do get bad hangovers. I think I tend to order the low mood sometimes
and if you do and then you crank a hangover on top of it. That's really going to turn it up.
and I just had one really bad hangover one day
and I was like, I'm not going to drink for six months
and I just had this idea in my mind.
So I went six months sober and loved it.
And then I was in Bali and had a corona.
It was like, okay, I've done my six months
and I'll break it when I'm in Bali
and I'll go back to, yeah, I'll see what drinking's like.
I did it for three months, really didn't like it.
I'm going to do another six.
Went back for one or two weeks after that,
had one or two, a couple of beer nights out and did it for a thousand days. And then
since then, basically, I'll drink less than five times a year and it will be a beer or a couple
of beers or something like that. And I'm curious, when you drink, what is the effect? Do you get high,
energized, sort of fast or does it chill you out? It's a good question. And it's harder,
it's harder to answer than you might think. Like, it does. I would say, I would say in the past it
might have been, and this is what I said earlier on, in my 20s, it reminded of being more
energized and it being enthusing also would have been coupled up with unspeakable, unpronounceable
drugs from a guy in a toilet somewhere, which, you know, will supercharge anything. Yeah. Well,
and there's also the social aspect, right? So if you're going out and your friends around and
there's loud music and you're dancing, that's also going to be a natural amplifier of this
sort of euphoric effect. And I think it would be.
hard to parse out. Is that the booze or is that the mood?
Atmosphere, yeah. The collective effort. It's set and setting for alcohol.
But whereas now, you know, if I do have a beer or a glass of wine or something, it's as
we're trying to work out why everyone's commenting on the Ukraine when they don't have
any expertise in it over a good steak at dinner, you know, like that. It's a very different
sort of atmosphere. And maybe that is this sort of thing that I want. And also, I've generally
chilled out. I'm not sending it in the same way that I used to previously. Anyway, I made a big
song and dance about this because it was as the show was starting and it was a big part,
going sober, what I called at the time elective sobriety, which was like choosing to as a
productivity strategy as opposed to for some sort of need. Yeah, sober maxing. Sober maxing.
That's it. It's correct. Yes, yes. I was, I mean, I still am. I don't think I need to
kind of fly the flag for it so much anymore. But it was a huge part of my identity for the first
sort of three or four years of the show. The reason I don't think I need to talk about it quite that
much is it's less of a big part of my life because it's more just habituated and that's kind of the way
that I exist. But also, I think the world has sort of taken that and run with it. You know,
what is it now? I think that the WHO says that there is no safe level of alcohol consumption.
This huge meta, meta, meta analysis by The Lancet came back and basically said that there's no such
thing is a safe level of alcohol consumption. That one glass of red one, oh, but the resveratrol
that comes from the red grapes, it's like, yeah, but it's being offset by all of the stuff that it's
housed in. You could just eat the grapes. Yeah, exactly. And it's not good. There is no benefit.
The one benefit that you could see is to go like a Warren Buffett style approach, which is the stress
of trying to be perfect, I'll kill you more quickly than your imperfections. And I can see a place for that.
But if you're looking just straight up physiologically, Huberman-pilled, like it's not, this is not,
the direction to go down. But it was a huge, huge part of me and my life. And I remember,
even for me, right, as somebody who wasn't dependent, wasn't drinking that regularly, was around
the party scene a lot. I remember how triggering it was for all of the people that I used to
party with when I'd say that I wasn't drinking. And especially if you're in your 20s, and especially
if you're the club promoter, you're supposed to bring the party. And that meant that when
I said I wasn't drinking, the responses that I got from people were, as far as I could
see, really outsized. I was very surprised by how triggered other people were by it, by how mean
they got. I was kind of in a fortunate position that I was the top of the tree within this
industry. So there was only so far that you could, like, it's like taking the piss out of Joe Rogan
for the microphone that he's not using anymore. And you're like, yeah, but he's like the guy that
runs it right so it's you know and it was kind of the same at least a little bit in the world of
club promotion for me that it's like you could push me a little bit but not that far however one of
the things that did happen was people stopped inviting me out yeah you're a downer they didn't
want to and the other thing which I'm sure that you've seen too and it must be a difficulty must be
why it's so hard if you're friends with people who use alcohol to get sober is that your sobriety
throws their drinking into sharp contrast yes and other people do not
like the spotlight being placed on them in reflection of somebody that's making a change.
And yeah, I mean, I wrote so much about this, about the fact that if the only friends that
you can bear to be around are ones that you have to drink to be able to spend time with,
then you don't have friends who have drinking partners.
If the events that you're attending are ones that you need to consume alcohol to be able
to get through, then the problem is not your alcohol use.
The problem is the shitty events that you're going to.
like, you know, just this endless list of very obvious insights in retrospect that were all
couched underneath this lifestyle that uses alcohol. Like in the UK, I don't know what this is the
same in the US. I haven't seen it here even though I fly a lot. In the UK, if you go to any
working class town airport, Newcastle, Manchester, Liverpool, Birmingham, something like
that, if you go to any of those airports between the months of March and October, summer holiday-ish
trips six in the morning five in the morning the bar will be open and people will be treating the
opportunity to have a beer like it's this it's like it's naughty like it's sort of it shouldn't be
allowed but oh we're going to treat ourselves to something and i always found that so fucking
cringe like i always i always found it so i was like oh my god the the highest point of of subversive
a, like, anarchistic contribution that you can have is having a beer at five in the morning.
And I get it.
Like, people are allowed to enjoy what they're allowed to enjoy.
But I don't think that people are enjoying that.
I think they're enjoying the story that they tell themselves about what that means.
And I think that that's something which is much easier to change.
And it's something that I'm seeing.
So, yeah, again, my long-winded way of saying, oddly enough, even though alcohol was never something
that was a huge part of my life, going sober was massively formative because it allowed me
to finally get a fucking meditation habit and finally actually wake up and go to bed at the same
time, finally actually get some journaling done, finally start a podcast and do it. Because I wasn't
resetting these very difficult to do habits, right? You're going to the gym and eating well and
getting up on time and doing all the rest of this stuff. It's hard enough to do as it is. If you're not
shaking the etcher sketch every two weeks to reset all the program and then day one no chance and day
two still kind of not in day three oh okay maybe i'm sort of slowly getting back there and i always wondered
like why am i just it permanently feels like i'm not making progress at the speed that i should and um
the answer was kind of really subtly staring me in the face yeah which is well you're you're choosing
to kind of give yourself an illness for a couple of days twice a month right and right and and
That was it. Yeah, I found that after I got sober, I found that it almost felt like a life hack. And this is not like, like I'm not a maximizer. I'm not anything pilled. Well, I'm naltrexone pilled. But it did, it did feel like a life hack because I lived for so many years with this mental obsession, the physical, the physical effects of alcohol, but especially the mental obsession that was such a distraction from anything else in my life. I couldn't optimize shit. I still can't really optimize shit.
How did you get anything done?
Because I've listened to your podcast.
You seem to have a really fantastic recall.
You've got great stories.
You were working as a writer.
The book's wonderful.
I love the pods that you've done in the past that I've heard.
Those do not smack to me of a person whose brain has been addled by alcohol,
who's never been able to think about anything,
who's had their mind cycles captured by worrying about where the next drink's going to come from,
or if my wife's going to find those bottles that I hid in the back garden or whatever.
Yeah.
That doesn't smack me as that.
So are you the prototypical functional alcohol use disorder person or what?
Well, I wasn't for a long time.
So until I was 30, I worked dead end entry-level jobs that I was usually fired from within a few months and spent all of my time at a bar, at the bar.
There was one bar I liked in particular.
And then at 30, I started to get my shit together.
I took an unpaid internship at a public radio station.
And I did this purely.
out of pettiness because I had been broken up with someone who worked in public radio.
And I was like, bitch, I'm going to get your job and I'm going to do it better than you.
I'm going to, I'm going to win.
That's how petty I am.
And so I started to get my shit together then, but it was still, I was still working at a deficit because, and I also moved a lot during this period.
So I would live somewhere for a few years, maybe I think at the max at the most, like four years.
And then I would kind of burn my bridges. I would run out of jobs. And then I would leave for a new town and I would start to cycle over again. That was actually a fairly effective way of getting clean for at least a little while, like removing myself from the environment that I was in. But so I really did not start even really attempting to make career moves until I was 30 years old. And then I got, I did get serious about, I decided I was going to be a journalist. And I did get a
serious about that, but I still had many, many setbacks. And at that point, I had kind of
aged out of, like, heavy, like, club culture and party culture, because just, like, my friends
weren't doing it as much. So I did much more of my drinking at home by myself. So I really shifted
around that period to, like, being the girl, being, like, a party girl who everybody knew
is a party girl, to being somebody who had a much more, like, not, like, equally problematic,
but much more private drinking experience. And there are lots of people. And there are lots of
people who when I was reading when I was working on the book I talked to an entrepreneur who I
will not mention his name but you have heard of him who was drinking 40 drinks a day like low
alcohol drinks but 40 40 beers a day who also got on the low alcohol beers a day it's just an
immense amount of liquid he probably had to wear a fucking diaper so right and then and also like
think about the 1950s right when people are having three martini lunches and then going back to
the office after this, you know, that has almost completely left the culture. So we're just,
our standards really have changed. And then, go ahead.
Just we have like, what is acceptable and what is considered problematic drinking has changed
so much that like what I consider problematic drinking would not have registered in 1950.
Yeah. I remember hearing some story about the introduction of tea houses or coffee houses,
I think into Great Britain
and when that changed from being the public house
where everybody would go to meet and talk during the day
and that encouraged a slightly sloppier type of conversation
to then oh well you don't just need to drink the alcohol
perhaps you can drink the caffeine and this was some sort of springboard boon
for idea generation and may have contributed to the Renaissance and stuff like that
what is I'm curious so I did I did study abroad
in the UK. And I chose there for two reasons. One, the drinking age was, is what, 18, and I was 20 at the time, or 19 or 20. And two, this is the less important reason you speak English. And so I did study abroad over there. And I had classes on Monday all day and then Tuesday until noon. That was my entire work week, like my school schedule ended at Tuesday at noon. And there was a pub on campus. The student union was an actual union.
And there was a pub and pool tables, and we drank fucking snake bites, that horrific, like half cider, half lager with a little bit of blackcurrant juice.
Yes.
And it's like worse coming out, coming up the next day. It's disgusting.
And just the drinking culture there was, I loved it. I absolutely loved it.
But I'm curious. I mean, yes, in the U.S., we have definitely seen, like, we can see this in polling.
Gen Z is way less.
boozy than, you know, millennials than my generation was. They're also having less sex.
They're seeing each other less. There's all sorts of downstream effects, I think, connected to
the phone. But has this changed in the UK at all as well? Or people still boozing it up there?
I think it's very similar. My colleagues and ex-business partners from the industry that I
spent my life in, it does feel a little bit to me like I sold Bitcoin at $120,000.
because the market has really hit quite an aggressive downturn.
It's just not the done thing.
And, you know, it is a confluence of all of this stuff
because if the nightclubs are less busy
because more people, you're not just competing as a nightclub
with the darts around the corner
or the Huberman podcast telling you
that you shouldn't be drinking alcohol.
You're also competing with Netflix and HBO and TikTok
and just the vegetable culture.
Yes.
going to veg out on the couch and you're competing with changing dynamics in terms of what
people tell. Well, weed is now more prevalent in the UK. I know it's massively, maybe even
to the stage where more Genzi smoke and drink now, I think. So there's a lot of competition
for what your potential substance of choice is, whether it's the environment that you're
going to be in, whether it's the people that are around you, whether it's the social norms about
that, whether it's the education level that you've got and the understanding of the health effects,
whether it's the alternatives that you've got to get a buzz on,
whether it's the screens that can stop you from going out of the house at all,
whether it's the social anxiety from being arrested development during COVID.
It really is, in many ways, a perfect storm to stop people from drinking.
And in many ways, in many ways that's good.
But I mean, we are already seeing how quickly the world's turned.
Only a decade ago, for me, it was revolutionary to say that I wasn't going to drink.
And now we have, I think I saw a Scott Gavis.
Holloway clip the other day of him saying, I would way rather someone go out and get smashed
than sit in the house and like stare at the screen. Because very quickly, as with everything,
the pendulum has swung so quickly back the other way. They're well, no, I'm worried about this thing now.
You've got to be concerned about the, you know, isolation. So, yeah, it's vicious.
I think that's a completely legitimate fear because it's not just that young people aren't drinking,
which it's hard to argue that that's not a net positive, but they're also not socializing with
each other in person. And I cannot see that as a net positive. They're not having sex, which
you know, maybe there's some net positive there as well for, you know, we want people to have
to be responsible with their bodies. But if we have, you know, generations of people coming up
who don't know how to interact with each other in person, I don't know. It was, I mean,
that, that right of passage thing that I said, it really is. And as much as could I have
could I have learned the lessons that I needed to without going out and partying?
Maybe, maybe, but given that whatever it is, you know, maybe 90% or 95% drink 50% of the alcohol,
it seems that most people aren't graduating into becoming alcohol dependent.
Yes.
And if that's the case, there's probably a pretty good argument to be made that it is maybe a net positive,
that it does sort of expedite your learning.
How many people met their partners?
You know, meet your girlfriend in a nightclub.
Is that the best place?
At least the girlfriend for the week or the night.
That's true. That's true. That's true.
Yeah, it is a, it probably is.
There is certainly something that's been lost from that.
And the sort of massive surveillance culture that we have, I think, that made everybody much more worried about messing up or doing something embarrassing.
We used to do this barcrawl called Carnage, which was a T-shirt barcroll.
and you wore the t-shirt as your ticket
and then there was tasks on the back
that you had to tick off like pulled a pig
swapped shoes with a random
um wait pull a pig
pulled a pig like got off with somebody
who's really ugly and fat
oh that's terrible that is so awful
it was 2006 okay so we were allowed to
make sense
it was a different world
and um
different it means a different thing in Austin
that's a that's a barbecue joint
that's true um
that
Larry Louty culture would not, you would not even be able to get two feet down the street
with that in the modern world because this fucking surveillance state run by gullible volunteers,
this sort of starzy for the Angry Birds generation, would have captured everything.
So you pulling the pig or you throwing up in a bush somewhere, that is immortalized
on the internet for the rest of the time.
At an even younger age, when I was a kid, when I was
15, my parents left me at home for a weekend. I hope they're not listening to this. If they are, I'm sorry. I fucking took their car and I drove around all weekend. I had a giant party at their house. They never found out. Today, they would have a tracker on me in the form of my phone. And every neighbor would have a ring camera or they would have a ring camera. Capturing you as you go past. Yeah. So I don't know how young people today get away with shit. And I do think those are valuable lessons to learn.
I'm not sure what the value is, but I think it's still valuable.
It's fascinating.
So is this, what is it that you're hoping to achieve with this?
Are you hoping to make more people aware that this is a particular solution for people that are drinking too much?
Is it to sort of campaign to make this more widespread among doctors?
All of the above, yeah.
I want, the main message of the book is, you know, the book is about the Sinclair and Maths,
in the Ltrexone, and it is sort of a step by step. This is self-help, which is the fact that I, Katie
Herzog, wrote a self-help book would shock anybody who knew me 10 years ago. It's definitely a twist.
No one's all this coming. So, but part of it is to give people a guide because when I was doing this,
there were YouTube videos in Facebook and Reddit and lots of, you can hire coaches who are really
helpful in terms of helping people know what to expect, how to deal with side effects and setbacks and
things like this. Trying to figure out if it'll even work for you in the first place. But I wanted
a book. I wanted something I could read that would tell me what to expect on day one, on month one,
on year one. And that didn't exist at the time. So that's part of it, just giving people a guide.
But I also, you know, now Trexone isn't going to work for everybody, but there are lots of other
options out there. And I just, I want the conversation to shift from there's one path out of
alcohol use disorder and not is abstinence only to just broadening the way that we think about this
because that that option does work for a lot of people but it doesn't work for everyone and I think
the problem with the the AA or nothing narrative or the abstinence or nothing narrative is that it
keeps people drinking longer so I thought that for years I thought that the only solution to my
problem was going to be to quit drinking and to quit drinking forever I had I did do
that in the end, but it wasn't, wasn't what I expected. And that, that was such a mental
barrier for me that it kept me drinking much longer than I should have. And had I known that there
was a way to continue to drink, because that's what I wanted to do, continue to drink, but do it
in a way that was safe and that would extinguish my desire for alcohol, I would have taken
this step, I think, a lot earlier than I did, and I would have saved myself some heartache in the
process. And you wouldn't have had to write a personal development book, but here we are.
I've done it. And it's actually really good. Yes. Yes. I mean, not only did I have to
tell my, come out and tell my parents that I had been secretly drinking, I had to tell them
that I wrote a self-help book. It's humiliatings, Marion. The price that you pay to try and help
the world become slightly better. My God. Katie, you're great. Where should people go to check out
all of your stuff? You can pre-order the book. It's on Amazon, all that stuff. You can go
my website, Drink Your Wasteober.com or org. Not sure. Google it. And I also have a podcast. It's
called Blocked and Reported. We do not talk about self-help or drinking culture. We talk mostly
about the internet and culture. A lot of talk about furries. We've been on a furry kick lately.
Okay. I haven't seen those, but your blocked and reported is awesome. And everyone should go
and check that out. So are you. I really, really appreciate what you've done. Thank you for having me.
It's great to talk to you.