Muscle for Life with Mike Matthews - Ben Greenfield on How to Live a Longer, Healthier, and More Enjoyable Life

Episode Date: August 10, 2018

In this podcast I interview bestselling author and competitive triathlete Ben Greenfield, and we talk about how strength training, muscle building, exercise, and diet affect aging, longevity, and heal...th. If you follow Ben and his work, you know that this is his primary hobbyhorse. He’s obsessed with figuring out innovative and cutting-edge ways to improve his body and mind, and in this show, he shares some of his most recent thoughts and strategies for optimizing his life. Here are some of the things we talk about in this episode… The role of muscle mass and strength in aging and longevity. The effect of protein intake and intermittent fasting on health. The ketogenic diet for performance and health. And more... 11:12 -  What are your thoughts on muscle mass and longevity? 16:56 - What about the research showing an association between longevity and total lean mass? 23:53 - If you have sleep, diet, training, and stress under control, how much does it matter if you don't fast, or eat protein daily? 24:41 - Is moderate drinking helpful or hurtful? 27:27 - What is hormesis? 30:23 - How important is exercise? 32:56 - What are your thoughts on the ketogenic diet? 41:37 - Does everyone wake up in ketosis? How long does it take to become fat-adapted? 45:18 - What about the saturated fat and the paleo craze? 49:13 - Do you have any projects you're working on? Want to get my best advice on how to gain muscle and strength and lose fat faster? Sign up for my free newsletter! Click here: https://www.muscleforlife.com/signup/

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Starting point is 00:00:00 So, ultimately, small amounts of extremely functional muscle and a very high power-to-mass ratio is what you should shoot for if your goal in training muscle is longevity. Hello, hello. Mike Matthews here from Muscle for Life and Legion Athletics, back with another interview for the Muscle for Life podcast. And this time around, I talk with the one and only Ben Greenfield, who is a best-selling author and competitive triathlete, and also a podcaster, content producer, entrepreneur, all around neat guy doing a lot of neat things. And we actually didn't really know what we were going to talk about going into this interview,
Starting point is 00:00:52 but ended up on the subjects of strength training, muscle building, exercise, diet, and how they affect aging, longevity, and all around health and wellbeing. aging, longevity, and all around health and well-being. And if you follow Ben and his work, you know that that kind of stuff is his primary hobby horse. He is obsessed with figuring out innovative and cutting edge ways to improve his body and mind. And he is not afraid to experiment on himself. And in this show, he shares some of his most recent thoughts and his most recent strategies for optimizing his life. So here are a few of the things that we talk about in this episode. We talk about the role of muscle mass and strength in aging and longevity, the effect of protein intake and intermittent fasting on health,
Starting point is 00:01:46 the ketogenic diet for performance and health, and more. Oh, and for those of you who are wondering how the third editions of Bigger, Leaner, Stronger and Thinner, Leaner, Stronger are coming along, they are coming along very well. I'm actually done with my second draft. I'm working with the editors, which I guess that's the third draft. And then next week I will start recording the audio books. I expect that to take two to three weeks and that will serve as the fourth and final draft. And then it's really just a sprint to produce the publish ready files, the ebook files, the audio book files, the print files, the files the printer needs to start printing the new books. And I expect that everything will be out
Starting point is 00:02:36 by early December. I am going to release the ebooks and the audio books first, and those should be out live, ready to go in October or November. And by the way, if you've already bought one of the eBooks or audio books, you are going to get the new edition for free because I'm simply going to be replacing the existing files with the new stuff, which means you will get a notification. I think you get notification, that a new edition is available and that you can update what is sitting on your device, on your phone, your Kindle, whatever. And if you don't get the notification, you'll be able to simply manually update the books. So that's where those projects stand. Oh, by the way, I'm also updating the year one challenges, the workout journals for men and
Starting point is 00:03:22 women as well. Excited to get the new ones out because not only are the programs changing a little bit for men and women, but the journals are also going to contain more helpful information. They're going to be more of a reference guide than they currently are. And the journals will be coming out at the same time as the new books. time as the new books. So that's the update. And I have a couple, two, three weeks of intense audio book recording ahead. And then I will be back to my normal schedule of writing for the blogs and recording the podcast and so forth. I decided to put everything on hold so I could get through these new books as quickly as possible because it meant the difference of doing it all in about six weeks versus probably what would have taken four months if I would have tried to
Starting point is 00:04:11 squeeze all this stuff in in between all the normal work that I do. So I decided to put all the normal stuff on hold and just get through this third edition project as quickly as possible. And I think it was the right decision because I'm very happy with how these new books are coming together. And I'm very curious what you and everyone else who is going to read them thinks. And lastly, this episode is brought to you by me. Seriously, though, I'm not big on promoting stuff that I don't personally use and believe in. So instead, I'm going to just quickly tell you about something of mine, specifically my 100% natural whey protein powder whey plus. Now this is a naturally sweetened and flavored whey isolate protein
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Starting point is 00:06:29 all over the internet. And if for whatever reason, they're just not for you, contact us and we will give you a full refund on the spot. Mr. Greenfield, welcome, welcome. Thanks for taking the time. I think this is the first time have we spoken? I mean, yeah, I think so is the first time have we spoken i mean yeah the first time we've ever spoken on my show could be thanks matthews i've had you on my show
Starting point is 00:06:53 and uh yeah i don't know if i ever have been on muscle for life muscle for life that's me yeah you know what's interesting, though? You could argue that muscle might confer decreased longevity. Really? Because that's like the opposite of what people generally think. Why is that? I know. I know. And there's a lot of especially gentlemen attempting to get jacked, you know, as they go into old age. But fact is, and Paul Jaminet actually wrote about this a long time ago in his old book, The Perfect Health Diet. And since then, there have been plenty of studies. I mean, you could even go to PubMed and do a search on muscle quality longevity. And it turns out that because muscle takes a lot of energy to carry and cool and requires you to have a ventricular hypertrophy, enlargement of that left ventricle of the heart. could cause a decrease in longevity compared to a fast twitch muscle that's kind of like the small,
Starting point is 00:08:34 compact, powerful, wiry muscle, such as you would find in say like a power lifter. So ultimately, small amounts of extremely functional muscle and a very high power to mass ratio is what you should shoot for if your goal in training muscle is longevity. I mean, yeah, I could see that. Although I would say your average power lifter is not small, maybe small by like Instagram narcissistic. Yeah, it depends on the power lifter, right? Yeah. I mean, there's some guys, some power lifters that are, of course, the stereotypical Russian with the enormous belly powerlifter who can rip 500 pounds off the floor and hoist it overhead. But then there are very small, kind of wiry powerlifters that kind of are not the ones
Starting point is 00:09:18 that you see on TV or on YouTube as much. But I've talked to a lot of these small, wiry guys that are just like super duper strong. You shake their hand, they've got an iron grip, but they don't necessarily, they don't look like the guys who'd have like biceps bulging out. They're welcome to the gun show t-shirt. So it's kind of interesting. Yeah. I mean, you have obviously anatomy is in play in there. Some people's bodies are just built to be strong. Yeah. Muscle insertions and so forth. And then it also, of course, depends how you train. What would you say if you were to, this might be just stretching, but if you were to extrapolate
Starting point is 00:09:55 that to some sort of FFMI, right? So like once you start getting, once you start getting upward of 25, you're pretty, you're pretty huge and you're probably reaching about the top of, let's say, 25 to 27 being probably the top of what is naturally achievable for the vast majority of people, at least. I think I'm around 23 or so, and I really don't have any desire to be bigger than I am. Wait, what are you talking about? BMI? No, no. FFMI, free fat mass index, right? So, like the relationship between your height and your total muscle mass, which is, it's usually used as a proxy for, is he natty bro?
Starting point is 00:10:31 Right? So how high is his FFMI? When you see somebody with like a 29 FFMI claiming natty, like, no, never. It's just not possible. You only can get so muscular unless you're talking about like a six foot eight dude who has nine inch wrists and has just been a freak show his entire life. But for the average person, you only can get so big naturally. So with what you're talking about with- Yeah. Above 25 is considered to be like
Starting point is 00:10:56 mildly sterodal, right? Yeah. Yeah. You're huge. Again, I'm maybe 23. I'm in the 23s and I'm big by, I guess, maybe normal standards. I'm kind of small and whatever by Instagram standards. But as far as longevity goes, what are your thoughts there? Take me, for example. I don't consider myself a bodybuilder. I've never competed. I don't think I would do well because I would be scrawny by bodybuilding standards, but I look like a fitness guy. You know what I mean? Right. Exactly. I haven't seen many correlates between FFMI and aging, but I haven't looked much either at what's out there in PubMed, for example, as far as anything that's been looked at correlated to that. But what I can tell you is that a lot of the
Starting point is 00:11:41 popular theories of aging are based on maintenance versus reproduction, meaning in an ideal scenario, you would strike a sweet spot between having a body that does not require a great deal of maintenance and a great deal of antioxidants to actually take care of and repair and recover. And at the same time, you achieve a sweet spot for reproductive capacity, meaning you maintain a certain amount of reproductive usefulness and studies that have looked at women and their age of childbearing and their number of children. For example, it confers a significant improvement in longevity when you have A, had a lot of kids at an early age and B, continue to have kids later into life.
Starting point is 00:12:25 And interesting when, when we look at men and women, fertility is of course affected by hormone status, by cell membranes and by, you know, available fat stores. So of course, you know, as FFMI increases, if the increase were due to, you know, for example, a significant decrease in body fat percentage to the extent to where you might reach, you know, andropause or progest it either is making babies or is capable of making babies frequently and into old age. And that based off of the, this theory of reproductive usefulness, uh, is, is a pretty good idea if you want to keep yourself around for a long period of time. And you look at a lot of these blue zones, right? Like the last one that I believe was a story in the New York Times, this little village in Acirelli, Italy, they're known for eating high amounts of rosemary, specifically a form of rosemary that's very high in rosamarinic acid, which is this stuff that has a really, really good antioxidant effect and a little bit of a natural built-in plant defense mechanism. So your body responds with this hormesis response of stepping up its own antioxidant production. But then the men who live in that village are
Starting point is 00:13:58 having sex up to a very old age, like 90 a hundred years old and still having sex two to three times a week, which is a lot for somebody that age. So it appears that, uh, that, uh, it's not necessarily just about being swole and may not even be about being that swole as much as it is about being fertile, sexy. Yeah, exactly. Sexy and sexual. And honestly, it's kind of weird because those two often contradict one another. You look at the cover of many popular health magazines and the way that sexy is defined often confers andropause and the female athletic triad syndrome and all these issues correlated to very low body fat percentages or overtraining or both. Yeah. I mean, the same thing goes for guys, right? You only can be so lean for so long and train so hard before you start to feel the effects of it. And. Oh yeah. I mean, I've, I've been there as, you know, from, you know, I, I used to do bodybuilding and maintain very low levels of body fat percentage, you know, by eating tuna with relish stirred into it for dinner every night. And, you know, then I moved on to Ironman Triathlon, where I also competed for 10 years at a very lean body fat percentage and more of a chronic cardio approach.
Starting point is 00:15:18 But neither lent itself very well at all to thyroid optimization, testosterone optimization, really any hormones whatsoever. I mean, across the board, neuroendocrine issues with both of those sports, whether, you know, one was focused more on mass building, one more on staying lean for a good power to weight ratio, but ultimately, you know, neither are a healthy sport. Yeah. Yeah. You know, something just what you're saying with fertility is, I forget who it was. It was a doctor, one of the, one of these more prominent doctors who whose work I like, I don't remember who, but was saying that fertility is, is a good general indicator overall health. So just what you were saying in terms of remaining sexual and sending that message to your body that, Hey, uh, biologically speaking, I'm worth having around. It makes sense.
Starting point is 00:16:07 Yeah, exactly. I mean, a lot of the studies on it, interestingly enough, are done in fruit flies, but there's actually pretty good data that you can extrapolate from fruit flies to humans. And a lot of these aging labs, because fruit flies can produce another generation so quickly. I mean, you can study, I don't know how many dozens of generations of fruit flies over just a few years in a lab, but you can get through a lot more than you can like rodent models or human models. So ultimately you can learn a lot about aging from these fruit fly populations. There's some, some, uh, conclusions that you probably can't extend to humans, but this reproductive one seems to make sense. It just makes logical evolutionary ancestral sense, and it also seems to flesh itself out when we look at a lot of these blue zones.
Starting point is 00:16:54 Interesting. And what are your thoughts on the research that's out there that shows an association between longevity and – I mean, it really is just total lean mass, right? So like, as you get older, if you don't do whatever, starting in your 20s for most guys, right? If you don't do anything about it, you're going to start losing lean mass. And that just kind of carries on throughout your life and your metabolism dwindles with it to some degree, which it seems like loss of muscle is the primary driver of that. And by at least halting that, which of course requires some sort of resistance training, it doesn't require bodybuilding or weightlifting. I mean, you could probably do it with bodyweight training, but at least not losing lean mass as you get older is associated with longer
Starting point is 00:17:40 life and reduced all cause mortality. At that at least that's my understanding of the research that I've read. Yeah. I mean, more particularly some of the more compelling research seems to, seems to look at some variables that are a little bit more nuanced, you know, particularly hand grip strength. You know, that that's one. Yeah. I was going to say like grip strength, having your body work. Exactly. Grip strength across the board. Poor grip strength is an independent risk factor for type two diabetes, for cardiovascular disease. Another one is walking speed.
Starting point is 00:18:12 And that's another interesting one. Like the fastest walking speed has an inverse correlation to mortality. And so you tend to see. And what is that? What does that mean? Exactly. That means just in your day-to-day living? So basically, what the most recent study found was that rapid declines in walking speed actually predicts early death. So as soon as you start to slow down in walking speed, it means that you're not necessarily nearing death's door, but it's a pretty good sign that you're aging more quickly.
Starting point is 00:18:41 So hand grip and walking speed, muscle definitely has been correlated in many cases with longevity. But again, I think it's more the quality of the muscle than the quantity of the muscle. And those do go hand in hand to some degree, right? Yeah. Yeah. And there's one longevity protein that's pretty dependent on the strength of skeletal muscle. I forget the name of the protein, but essentially it's much more dependent on strength than the actual number of fibers or the mass of the muscle itself. So I think that the, yeah, the corollary with muscle mass is more the strength that the muscle confers than it is just the, you know, the amount of muscle itself, because, you know, muscle, unless it's actually producing some kind of functional usefulness, is just extra maintenance.
Starting point is 00:19:30 And then we go back to that maintenance versus reproduction argument. It'd be better to focus on your reproductive capacity and your fertility than it would be your actual muscle. But yeah, from a fitness standpoint, it usually comes down to hand grip strength, walking speed, and then muscle quality, muscle strength, more or less. Yeah, that makes sense. I mean, but there is obviously a relationship between muscle quality, muscle strength, and muscle size. I mean, if you're going to be strong, you're probably going to be a bit bigger than the average person, right? Yeah. Most strength training programs confer a pretty significant increase
Starting point is 00:20:05 in mass. I just think there's a law of diminishing returns. But again, part of this comes down to the nutritional component too. I mean, I was recently at a mastermind with a bunch of physicians and many of them were focused on longevity. And when we look at anything from, you know, like a pulsing approach to management of cancer, to anabolic catabolic cycles, to ensure that you have enough mTOR and enough insulin-like growth factor and enough insulin to maintain some amount of anabolism, but then not so much that you just have undifferentiated cell growth and accelerated aging. It seems to come down to a pretty good balance between the two and specifically related to this discussion, not being in a constant anabolic state, not having mTOR constantly activated. And so in a situation like that, it would mean, well, focus on strength
Starting point is 00:21:03 training, but don't necessarily face stuff all the time. Look at like a protein restricted diet on specific days or alternate day fasting or an intermittent fasting approach or macronutrient adjustments based on how heavy your strength training or your training in general is for that day. And accept the fact that you're not going to eat the same thing every day, the same amount every day. And instead you're going to have certain days where you enter more of a catabolic cycle, or at least certain periods where you enter more of a catabolic cycle and certain periods where you enter a more anabolic cycle, you know, and, uh, you know, that, that can manifest in a variety of scenarios. It could mean that you're going to eat
Starting point is 00:21:43 red meat, but you're going to only have like large portions of red meat two to three times a week. Or you're going to have certain workouts where you fast after the workout, which may actually cause a slight improvement in growth hormone and testosterone. And then you're going to have some workouts where you feed after the workout. Some days where you fast, I typically fast once a week for 24 hours. That's a pretty catabolic 24 hours. I've just got water and minerals and multivitamin. I'm not training hard during that time, but the amount of cellular autophagy, cellular cleanup, and even the decrease in the amount of stress and throughput on the gut is pretty significant by me entering that cycle. So I think a big part of it is, you know, if you're pairing an intelligent strength
Starting point is 00:22:31 training program along with certain days where you have macronutrient adjustments or protein restriction, or at least you're going out of your way to not be constantly triggering insulin and IGF-1 and excess anabolism, then you're probably not going to get so huge that it begins to confer a decrease in longevity. Yeah. I mean, I think having worked with many, many people, most guys, and certainly most women who obviously can build muscle just fine, but start with a lot less of it than guys, who obviously can build muscle just fine, but start with a lot less of it than guys. And so are kind of hamstrung from the beginning. It's very hard to get jacked like that is without drugs takes a tremendous amount of not just hard work, but smart work, not only in the gym in terms of programming and
Starting point is 00:23:21 continuing to accelerate volume, continuing to accelerate intensity over time. But also, like you said, on the nutritional side of things, it takes very strict, well, fairly strict dieting when you are in a surplus, as well as when you're in a deficit. Many people are strict when they want to lose fat and they get it done and then kind of just go back to an intuitive eat by feel approach, which obviously isn't, isn't, isn't optimal for trying to gain muscle and strength as quickly as possible. Um, but I wonder how much all of that matters. And that's, this is, and this is may, may come from just my, my ignorance and not having read enough research, but you know, when I just
Starting point is 00:24:02 coming from what I have, what, from what I have read and the understandings that have come to, I just wonder how much minor things like this matter when you get all the major things, right? Like you are exercising several times per week. You are not overweight. You do not smoke. You do not drink. You do, you have good sleep hygiene.
Starting point is 00:24:20 You're not stressing yourself out, you know out just in life and in general. And if you have those big things in place, I wonder how much does it really matter that you don't have any fasting in your routine or you just eat protein every day? You know what I mean? Well, when you look at things like blue zone data or longevity data, I mean, some of the things that you just said, we could almost argue against, right? Like, for example, not drinking, right? Well, it turns out that one to two drinks a day is associated with decreased mortality risk, specifically like tannin and antioxidant-rich beverages such as red, you know, or, or ferments, you know, like, like a kvass with alcohol, you know, we see a lot of these in these longevity hotspots. So it appears that it's not, not drinking. It's actually drinking in moderate amounts,
Starting point is 00:25:13 the same with stress or like low level hormetic. Well, I mean that, that, that correlation though, again, that's not an area that I have read much up on. I've listened to, there was somebody in particular, I want to say he headed up a research board. It might've been for Life Extension, which is a supplement company and that's fine, but they have a big board of researchers, MDs, PhDs, smart guy was talking about alcohol. And this was like his pet project for, I forget his name because it was over a year ago that I listened to the interview, but alcohol was his pet project. And he had read an absurd amount of the literature looking for what he considered convincing evidence that alcohol was
Starting point is 00:25:53 healthful in any amount at all. And again, I'm passing this along more as a, I'm saying it for what it's worth because I haven't done the direct research that he has. But his conclusion was that alcohol is a poison in any amount. And the long story short is some people's bodies just deal with it well. It's not really a positive for anybody. They're not missing anything if they don't have it. But some people's bodies deal with it better than others. So some people can drink and you really don't see as long as they don't go overboard, you don't see any negative effects, whereas other people could drink the same amounts and experience negative effects. Again, I can't vouch for one way or
Starting point is 00:26:34 the other. There's just something that's stuck in my mind because of who the guy was and the amount of research he had done. And it was interesting. There's certainly some genetic differences, you know, for example, Asian populations and their alcohol dehydrogenase enzyme results in a lot more acetaldehyde, you know, metabolic poison hanging around the system after they've drank. So there's certainly that, but, you know, a couple of things. First of all, yeah, alcohol is bad for you, but so is kale, so is quinoa, you know, so a lot of these plants with natural built-in defense mechanisms that seems to confer a hormetic response that allows you to actually bounce back stronger, just like solar radiation. And interestingly, in some cases, nuclear radiation and heat and cold all in mild to moderate amounts seem to confer longevity. So there could be the fact that it is a slight poison.
Starting point is 00:27:26 Can you just clarify hormesis just so the people listening know what you're talking about? Hormesis, I mean, in a nutshell, it's this idea that things that would be bad for you and excessively stressful in large amounts actually confer increased cellular resilience in small amounts. They equip your body to be able to, to bounce back stronger, which means that living your life in a bubble and never eating wild plants. And some would say even, you know, avoiding things like grains and dairy, or never subjecting yourself to a heavy load or not going out in the UVA and UVB radiation you get from sunshine, like you're gonna get pretty weak. If, if that's, if that's your approach to life, you know, to be living in a, in a digestive bubble or in an environmental bubble, it appears that
Starting point is 00:28:10 you do have to, to get out and, and do hard things in small amounts, which is of course, you know, most people would, would nod their heads in agreement. And then there's, you know, when it comes to the nutritional component, that's probably the one that's, that's the most argued over, you know, should you eat, um, should, should you eat wheat? that's the most argued over. Should you eat wheat that's like a non-GMO good wheat from a natural source and not worry about the gluten because frankly, those trace amounts of glutens that the wheat has as a defense mechanism could actually make your gut stronger and more resilient. People will argue over a lot of the plant-based things. There's books like Plant Paradox by Stephen Gundry, for example, that kind of gets into that.
Starting point is 00:28:50 But ultimately, the idea of hormesis is that you try to do some things that are just kind of sort of a little bit bad for you, but are good for you in small amounts. The idea though with alcohol could also be, and I'll certainly grant this, just imagine if you got around with all your friends for one to two hours in the evening and you drank water and laughed and socialized and hung out and you were surrounded by friends and family and this relaxed, de-stressed environment, well, there's never been a study that has actually looked at, you know, does it matter then if you're holding a glass of wine versus a glass of water, right? There are all those things that go along with a nightly consumption of alcohol from a social and a de-stressing standpoint that may actually be some pretty big confounding variables. I like to think that some of the natural hormetic defense mechanisms and some of the tannins and resveratrols and things like that and alcoholic beverages actually do give you
Starting point is 00:29:51 a little bit of that hormetic response. But ultimately, I think part of it is just the fact that social drinking to a certain extent can confer longevity just because we know that one of the top things a lot of these blue zones are doing is engaging in friendships and social relationships and hanging out with family and just being in those type of situations where you're de-stressing at the end of the day. But yeah, I mean, we got on this kick as you were talking about some of these more important things. And another thing would be exercise. We don't see exercise as a prevailing characteristic in any of these areas where people are living for a disproportionately long period of time. We don't see a lot of CrossFit wads or triathlons or Spartan races or bodybuilding or
Starting point is 00:30:38 much of any of that. You see low level physical activity all day long, typically in nature. And I realize that's a very difficult thing for someone living in a post-industrial era or westernized society to actually pull off. I mean, you can hack your environment though. I'm walking on a treadmill right now. I'll probably walk like five or six miles today, just low-level physical activity as I'm dictating emails and as I'm talking on podcasts and as I'm writing and reviewing and reading, I'm often either walking or standing or kneeling or lunging or balancing on this little fluid stance board next to my desk or doing something that kind of tricks my body into thinking that I'm gardening or gathering or hunting. There's a kettlebell over by the door, right? When I step over that thing, I got to do about 30 seconds of kettlebell swings. So I'm doing a little bit of high intensity speed work throughout the day. There's also a bar, a pull-up bar in the door of the office.
Starting point is 00:31:34 And my rule is I got to do three pull-ups when I walk underneath that. And then there's a hex bar right outside in the room next to my office. And I go in there three to five times a day and just lift it five times. All right. So, so I'm, I'm kind of engaging in this low level physical activity with a little bit of sprinting and a little bit of heavy lifting throughout the day to simulate what those blue zones do, because there really is not much of, of an exercise in a pill that we see in those environments. And, you know, there, there's even some evidence that it doesn't matter how hard hard you exercise the beginning of the day or the end of the day, if you have your butt planted in a chair for eight hours the rest of the day. So, you know, ultimately, I think that your statement that maybe a lot of this stuff doesn't matter if you're doing the little things is right.
Starting point is 00:32:20 Assuming that those little things are, you know, low level physical activity throughout the day, getting out in nature, fresh air, good sunshine, good water. We all know those have a profound effect on the mitochondria specifically, and then family, love, life, social relationships, perhaps with alcohol, perhaps without, who knows, but just that, that de-stressful time at the end of the day. Yeah. I think all those things are probably far more important than figuring out exactly how high you're going to spike your insulin post-workout. Yeah. No argument there. What are your thoughts on the ketogenic diet? All the rage these days. Yeah. I'm amazed at how well some of these ketogenic cookbooks are selling. I mean,
Starting point is 00:33:03 they're like, go look at the top 10 on Amazon and you know what that means. Like, dude, number one on Amazon means you're moving like 5,000 to 6,000 copies per day. It's nuts. And I'll even name some of my podcasts like Keto, This About Ketosis, That About Ketogenesis, Ketone, Esther's Keto, but because they freaking get downloaded like hotcakes. Anything that says keto, it's nuts. downloaded like hotcakes, anything that says keto, it's nuts. I delved into ketosis in 2013. So I guess about at the time of this recording, five, five and a half years ago when I was racing Ironman and I was looking for a good fuel for brain, for liver, for diaphragm, for heart during
Starting point is 00:33:42 long-term endurance activities. And ketosis was kind of a new thing, especially amongst athletes, amongst folks like, I guess, Terry Walls or people who are managing epilepsy and seizures and things like that. Ketosis was already a hot topic, but among athletes, it wasn't being used very much. And so I began to use MCTs. I didn't have access to ketone salts or ketone esters at the time, but I would use MCTs. I would use essential amino acids, a little bit of like a really slow release starch. Like at the time I was using the UCAN super starch, like a very kind of slow release starch that causes a lot of fermentation and bloating, I think, because a lot of it remains undigested, but ultimately it doesn't spike blood sugar.
Starting point is 00:34:29 So it's like a slow bleed carbohydrate you can use during exercise. And then just electrolytes, right? Because I found, as most people do, that my mineral and electrolyte needs went through the roof as soon as I started dumping all the glycogen I was dumping. And your potassium needs particularly go very high up when you're in ketosis. So I raced like that in a couple of races in Canada and then after that in Ironman Hawaii and just felt like it was rocket fuel to be in ketosis for these long endurance bouts, you know, where you're out there for 9 or 10 or 11 hours. long endurance bouts, you know, where you're out there for nine or 10 or 11 hours. And then the next year after that, I actually followed 12 months of strict ketosis, meaning that I was eating like five to 10% carbohydrates max. And that was for Jeff Volokh's faster study in which
Starting point is 00:35:18 he took athletes who rather than as they do in a lot of these studies, you know, follow a ketotic high fat diet for just like four days or two weeks leading into the study. He had people get what a lot of folks will call fat-adapted or turn to fat-burning machines, at least theoretically, by following a ketotic diet for six to 12 months. I did this for a year going into that study, and then they took the group that followed a high-fat diet, a ketotic diet, and compared it to a traditionally fueled 55% to 75% carbohydrate-based diet. And they did VO2 max tests. They did a three-hour treadmill test, which was horrible.
Starting point is 00:35:56 You just kind of stare at a white wall in the lab and run on the treadmill for three hours. And they collected muscle biopsy, fat biopsy, resting metabolic rate, exercise metabolic rate, blood microbiome, whole bunch of stuff. The biggest takeaway though was that they found that people who followed the high fat diet were burning 1.6 to 1.7 grams of fat per minute. When up to that point, most exercise physiology textbooks would say the maximum amount of fat one could burn
Starting point is 00:36:25 during exercise is like one gram a minute. So essentially, at rest and during exercise, the group that followed the high fat diet became very well adapted to burning fats as a fuel. And so it appeared to be from a performance standpoint, especially an endurance performance standpoint, a good hack. Now, at the same time, compared to following a traditional endurance-based diet of 55% to 75% carbohydrate, I had less gut distress and I had better endurance, but I had a horrible thyroid. I was getting cold. I was watching my TSH go through the roof. It got up to about between six and seven, which for clinical hypothyroidism, that might not be high enough, but it's definitely enough to cause concern for healthy people. I think it should be between about 0.5 to two for their thyroid stimulating hormone, their TSH. My testosterone plummeted.
Starting point is 00:37:25 I mean, my, my total T, uh, went below 200 and kind of started to get down towards like low one fifties. And, and again, like pretty sure my, uh, my five-year-old son might've had you beat. Yeah. Yeah. Or your five-year-old daughter. Uh, the, the thing is though, you know you know, there was a tradeoff, right? Like enhanced endurance performance, but at the cost of either metabolic downregulation
Starting point is 00:37:51 or neuroendocrine downregulation or both because of a lack of available glucose for everything from, you know, glycoprotein formation to glucans to, you know, to insulin receptors to thyroid receptors to, you know, to, to insulin receptors, to thyroid receptors, to, you know, everything that's necessary, you know, even, you know, enough for the cells to produce testosterone, obviously. So, um, since then I've been able to maintain, uh, ketosis, maintain a very low RQ, uh, a resting metabolic rate that relies primarily upon fat, but get my testosterone back up and my TSH back down along with adequate T3 and T4 by adopting a more cyclic approach, meaning that essentially I just eat a lot of plants, a lot of vegetables, a lot of oils, a lot of fats, seeds, nuts, cold water fish, small amounts of protein, and even include,
Starting point is 00:38:52 especially pre-workout, like a ketone salt or a ketone ester throughout the day. And then at the end of the day, I will eat ad libitum carbohydrates. Like last night, I had coconut ice cream in a waffle cone for dinner with a sweet potato mash and some sea salt. It was just like almost all carbohydrate. Tonight, I'll be taking my kids out to sushi. I do 100 to 200 grams of carbohydrate at the end of each day, tops off my energy stores. I wear a continuous blood glucose monitor. My glucose stays elevated for a very, very sane and normal amount of time after the meal. I also have ketone monitors in my office so I can duck down and check that if I want to. And I'm well into ketosis by
Starting point is 00:39:37 the time I wake up in the morning again. So I'm kind of able to have my cake and eat it too with that type of cyclic ketogenic approach. That's the way I coach most of the athletes that I work with as well, assuming they don't have familial hypercholesterolemia or they don't have some type of a gallbladder issue or anything else that might interfere with oil or fat metabolism. fat metabolism. But ultimately, that's the approach I take now after experimenting with ketosis for a while as a strict approach and finding it to be very unfriendly from a neuroendocrine standpoint, hormonal standpoint, overall energy standpoint. And we, of course, know that multiple studies have backed up this fact that it harms anaerobic performance, that it might not be all that great for the hormones, especially when combined with high levels of physical activity. So, I think that a ketogenic diet needs to be modified, especially for an active population. Yeah. And that's, I think, spot on. And that's the
Starting point is 00:40:38 key takeaway of people listening. So, I'm sure a lot of people listening, I mean, you just hear about it so much now and you have some very strong proponents of it who basically say it's, it's the next thing. Like this is, this is the next evolution of the human diet. And this is how we should all be eating regardless of our circumstances, our physiologies, our lifestyles, our goals. This is it. And yeah, I don't, I don't agree. You clearly don't agree either um now the do you find that the with what you're able to do now and with how quickly you're able to get into ketosis is that something that was you had to develop so to speak or yeah because i mean to somebody else to
Starting point is 00:41:19 somebody listening that'd be like oh so it's kind of like uh just car you know it's kind of like intermittent fasting but it's with carbs instead where you wake up. Sure, we all wake up. We stop eating whatever when we stop eating, depending on when we go to bed. We sleep for seven, eight hours and we wake up. That doesn't necessarily mean though that I'm not waking up in ketosis like you are. I would assume, right? You might be, but ultimately it takes one to two years for your body to become fat adapted, especially if you, like most westernized kids, at some point switch from breast milk, which is actually pretty high in ketone producing bodies, to Cheerios and Gerber sweet potato mash, and then cornflakes and cereal. I mean, we spend in America, at least, you know, from the time we're about two until we discover a healthy diet, if that ever happens, eating an extremely high amount of carbohydrate, really downregulating our ability to be able to efficiently burn fats as a fuel and,
Starting point is 00:42:19 you know, rely instead upon glucose and everything. That's where everything from like keto flu to, you know, poor energy levels to what typically causes someone after about two weeks to two months to drop off of a low carbohydrate approach to do so is because they don't give it enough time. One theory is that part of it comes out of mitochondrial density and that high amount of fatty acid oxidation could actually improve mitochondrial density. And you have to get to the point where your mitochondria are efficiently burning fat as a fuel and have increase in density to the point where you can feel really damn good on a high amount of fat and lower amounts of that, you know, that fast burning kindling versus the slow burning log. So, uh, you know, there are so many issues
Starting point is 00:43:03 though, you know, you talked about genetic individuality and, and, you know, there are so many issues, though, you know, you talked about genetic individuality and and, you know, we touched on that regarding alcohol. But you could also say the same thing of like, you know, starch digesting genes. You know, there are certain people I think it's the AM. It's like the AMY1 gene, something like that. But ultimately, some people do a really good job at producing salivary amylase, breakdown are very efficiently without a steep insulin response. And these would be like, you know, uh, some Pacific Islanders, some sub-Saharan populations, some Asian populations. And, uh, those people are people with, like I mentioned earlier, familial hypercholesterolemia, um, the, the APOE44 gene. There's a lot of people who have an inflammatory response or a digestive distress response or an elevated triglyceride and LP little a response to high amounts of fat, particularly saturated fats.
Starting point is 00:43:55 And so there are some people for whom a ketogenic diet would not only not be a good choice, but it could kind of kind of increase your risk of dying an early death. So I think that in an ideal scenario, you go out and you get like a 23andMe and feed that through a couple of analyses like Ben Lynch has a good program called Stratagene. There's a good one from Dr. Rhonda Patrick. I don't remember the name of hers. There's one called Genetic Genie. Patrick. I don't remember the name of hers. There's one called Genetic Genie. You want to look for SNPs that particularly affect your ability to be able to digest carbohydrate or to be able to digest fat or that reflect your ability to be able to handle high amounts of saturated fat, for example, along with your omega-3, omega-6 fatty acid ratios, and use that to
Starting point is 00:44:46 determine whether you would be a good candidate for something like a ketogenic diet. Because I would say there's a good, just an estimate, this is a total rough estimate, not based on science, just based on me looking at blood and biomarkers of some of the folks I work with and looking over genetic data, about a 10 to 15% at least portion of the population who do not do well on a ketogenic diet, or for that matter, even an intake of saturated fats that goes much above 10%. Yeah, I mean, I remember reading some saturated fat research a little bit ago, I was writing an article on dietary fat. and this is more in
Starting point is 00:45:26 response to the paleo craze, but the paleo craze has now kind of morphed into the ketogenic craze, it seems, from a marketing standpoint. And they're selling similar approaches, at least in terms of the high fat. And yeah, I've just had this discussion via email with a lot of people saying in simple words, you may do fine with a lot of saturated saying in simple words, like you may, you may do fine with a lot of saturated fat. You may do very not fine with a lot of saturated fat. And I, it's not, you know, I just can't in good conscience recommend just saying, yeah, sure. Cause you're not necessarily going to, going to know it right away. There could be things going on in your body, negative things that are accumulating and are happening that you're not aware of until I wouldn't, you don't have to catastrophize it,
Starting point is 00:46:11 but until you do become aware of it because it has gotten at least bad enough to where it's on your radar. And maybe there are things that have happened since paleo times. And I realized saying paleo times, like paleo diet isn't necessarily eat what your caveman ancestors would have eaten. But I mean, like when I look at the paleo movement, it's not just about, you know, shunning of modern agriculture, which I think actually lent a great deal to societal stability and defeating the world's population. But, you know, it also, But it also tends to now be heavily skewed towards polyamory and plant-based medicine trips that are just like ayahuasca and psilocybin, but not in stoic amounts, but like these big heroic hedonistic trips into plant medicine journeys. And you see this whole kind of like, I hang out in a lot of these paleo sectors and I love many, many aspects of the paleo movement. But I think that things like agriculture and monogamy and trading off deep hedonistic trips into plant-based medicine with a more stoic approach to drugs, I think all of this provided more societal stability and perhaps even conferred
Starting point is 00:47:34 greater longevity to the human race compared to just the whole, I realize we're opening up a huge can of worms here, but this whole plant medicine, polyamory, all agriculture is bad type of approach that a strict paleo enthusiast would endorse. I didn't know that that's part of the ethos because I don't – I mean, I'm just – I'm not active and I just sit in my cave and write stuff. Yeah. I don't interact with – You should dig into it sometime. and write stuff. Yeah.
Starting point is 00:48:02 I don't interact. You should dig into it sometime. It's, it's, um, yeah, I, I catch a lot of flack in, in,
Starting point is 00:48:09 uh, especially the paleo movement because, you know, I, I, I'm a, I'm a Christian monogamist guy who uses plant-based medicine in moderation, but turns down,
Starting point is 00:48:19 you know, all these invitations to go on ayahuasca trips. And, um, and, and, and I love to eat my wife's slow fermented sourdough bread and I've got little pygmy goats out back and, and, uh, I realized that this is blasphemous, but we milk them and drink their milk. Uh, which is horrible because no, no, no mammal drinks the milk of other mammals. No mammal also flies spaceships through the sky and invents computers.
Starting point is 00:48:49 We happen to have a large brain for a reason. So, I mean, probably a bad time considering I know we only have a couple minutes left for us to open that can of worms. Yeah, maybe for another discussion because that'd be fun. Yeah, yeah. I'd love to hear more about your bigoted fascistic views. So, you have a few more minutes. Let's wrap up with, I'm curious myself, what are, do you have any interesting projects that you're working on that you want to tell people about? Do you have another book coming? You had mentioned writing, is that more articles
Starting point is 00:49:20 or like what's what's on your plate right now? I am working on a book and the book really is more focused on some of the topics at hand, you know, on this podcast, like particularly longevity, you know, more of a focus on longevity and spirituality and even mental optimization than physical optimization, because I've written about that before. I have a book I'm very proud of. It's called Beyond Training, shameless plug. It's like 500 pages of how to biohack yourself physically, from digestion to sleep to muscle to endurance and beyond. But I feel as though I left a lot on the table when it comes to living a long time and being happy while you live a long time. So everything from purpose to happiness to spirituality to a lot of these woo-woo concepts
Starting point is 00:50:13 like quantum physics and movement of protons and their effect on epigenetics and also what we can learn from a lot of these blue zones, for example, that we were talking about earlier, I've filled a lot of the book, which is 900 pages long. A lot's going to go to the cutting room floor here when I finish, but that'll get published next year. If you go to bengreenfieldfitness.com, I will certainly send my newsletter list and an email once that bad boy is ready. my newsletter list and an email once that bad boy is ready. The other thing I'm working on right now, I guess if I could name one other thing I'm most excited about is this chocolatey, coconutty, gooey mess of mouth orgasm that I've been developing the past year and a half that is like this clean fueled bar that's got, you know, organic almonds and sesame seeds and coconut flakes and chocolate liqueur and cacao nibs. And it's, it's just like a melt in your mouth. Amazing,
Starting point is 00:51:15 mind blowing bar. And I'm launching that in a couple of weeks. I had the first few boxes arrive at my house a few weeks ago, my kids and my wife and I've been mowing through them. And so again, another shameless plug, but I would, I would say the book that I'm working on and also this new clean energy bar that I'm working on. Those, those are the two things I'm most excited about right now. The bar is called the, the Keon bar, by the way, that's, that's the name of my supplements company is Keon, K-I-O-N. So, so I'm excited about that too.
Starting point is 00:51:46 It's not ketogenic, by the way. Sorry to disappoint. I think we got that from the ingredients. And I'm going to humbly request a box because I and the guys here eat bars. I don't eat bars too much these days, but the guys- I'll send you a box along with our coffee. Our coffee is like you make a cup of coffee with our coffee and the crema on your espresso is like twice as high as you'd get from a normal, even my French press that I make with this stuff. The crema is like an inch high. The coffee tastes like, it tastes like chocolate and cherry. It's also amazing. Deliver the goods. I'm tooting my own horn. Deliver the goods. I will send you a box of bars and a couple of wonderful bags of coffee from Keon. Great, great.
Starting point is 00:52:29 They'll get used. We are coffee enthusiasts here. The espresso machine just gets pounded all day. All right. I'm writing a note to myself right now. Awesome. We'll ship it out. Well, thanks for taking the time, Ben.
Starting point is 00:52:41 This was a fun talk, fun talk. And I'd be happy to bring you back on whenever your schedule permits to go into the other stuff, which is really, it sounds like it's right in line with the book that you are researching and writing right now. So it might also be fun just from that perspective to, I don't know, that's for me in terms of the process. It's always helpful to go over your content and just have free flowing discussions about it. Cause sometimes new cool ideas come to you, you know? Yeah. I'd love to, man. It'd be fun.
Starting point is 00:53:11 Cool, man. Well, that's it for this time. Hey there, it is Mike again. I hope you enjoyed this episode and found it interesting and helpful. And if you did, and don't mind doing me a favor and want to help me make this the most popular health and fitness podcast on the internet, then please leave a quick review of it on iTunes or wherever you're listening from. This not only convinces people that they should check the show out, it also increases its search visibility and thus helps more people find their way to me and learn how to build their best bodies ever too. And of course, if you want to be notified when the next episode goes live, then just subscribe to the podcast and
Starting point is 00:53:51 you won't miss out on any of the new goodies. Lastly, if you didn't like something about the show, then definitely shoot me an email at mike at muscle for life.com and share your thoughts on how you think it could be better. I read everything myself and I'm always looking for constructive feedback. So please do reach out. All right, that's it. Thanks again for listening to this episode and I hope to hear from you soon.
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