Muscle for Life with Mike Matthews - Kurtis Frank on the Best Pre-Workout Supplements

Episode Date: April 10, 2019

Ten years ago, pre-workout supplements were for the unhinged looking dudes in the gym who nobody made eye contact with. You know the type: steroids, stringers, water jugs, strutting and peacocking, an...d the like. Back then, the pre-workout space mostly consisted of products like Craze, Jack3d, and Detonate (all of which have been banned, by the way) that contained mega-doses of amphetamine-like stimulants and little else. Fortunately, times have changed, and now we have pre-workout supplements that contain lower levels of much safer stimulants plus clinically effective doses of safe, natural ingredients scientifically proven to enhance performance and muscle and strength gain. That’s why people who take their training seriously aren’t asking whether they should take a pre-workout supplement anymore but instead which they should choose and why. And that’s what Kurtis Frank and I talk about in today’s interview. In case you’re not familiar with Kurtis, he’s the director of Research and Development for my supplement company Legion Athletics as well as the co-founder and former lead researcher and writer for Examine.com, which is the premiere online resource for science-based information on supplementation. Here’s a sneak peek of what you’ll learn in this episode: - What a pre-workout is - Ingredients that do and don’t significantly improve performance - How much you need to take of these ingredients to see benefits - The pros and cons of including creatine in a pre-workout supplement - And more. 5:43 - Interview 7:00 - Definition of Pre Workout 11:40 - Power output 18:18 - Alpha - GPC 20:12 - Alpha GPC dose 23:01 - How long before the workout should you consume? 31:39 - Best time to take creatine 34:32 - anaerobic 38:31 - Effective dose and timing of Citrulline 46:47 - Beta - alanine dose and timing. 49:09- What is betaine 59:05 - Aerobic 1:01:57 -Bad pre workout supplements Want to get my best advice on how to gain muscle and strength and lose fat faster? Sign up for my free newsletter! Click here: https://www.muscleforlife.com/signup/

Transcript
Discussion (0)
Starting point is 00:00:00 Well, a pre-workout, my basic definition is something you take before a workout for the purposes of either enhancing that workout or enhancing the benefits you would get from that workout. Hello there. I am Mike Matthews, and this is the Muscle for Life podcast. Welcome, welcome to another episode. This episode is about pre-workouts. Now, 10 years ago or so, pre-workout supplements were not nearly as popular, not nearly as mainstream as they are now. Back then,
Starting point is 00:00:37 they were more for the unhinged looking dudes at the gym who you really didn't want to make eye contact with. You know who I'm talking about. Steroids, stringers, water jugs, strutting around and peacocking, those guys. And back then, the pre-workout space, most of the products consisted of mega doses of amphetamine-like stimulants. Yes, you heard that right. Stimulants that are chemically almost identical to methamphetamine, but not quite so legally not methamphetamine. You probably remember some of these products like Raise, Jacked, or Jack 3D, as people would call it, and Detonate, and all of those have been banned, by the way. And so that's how it was. And that's also one of the reasons why pre-workouts were not all that popular. A lot of people didn't like how they
Starting point is 00:01:31 made them feel. They didn't like the racing heart, jitters, the anxiety and so forth. Fortunately, however, times have changed. And now we have pre-workout supplements that contain much lower levels of much safer stimulants like just caffeine, for example, plus clinically effective doses of safe natural ingredients scientifically proven to enhance performance and muscle and strength gain. And that is why people who take their training seriously are now not asking whether they should take a pre-workout supplement, but instead which they should take and why. And that, of course, is what Curtis Frank and I talk about in today's interview. Now, if you're not familiar with Curtis, he is the director of research and development for
Starting point is 00:02:18 my supplement company, Legion Athletics. And that does not mean that this is just a pitch for our stuff, because it's not. A little bit. A little bit of shameless plugging, but that this is just a pitch for our stuff, because it's not. A little bit. A little bit of shameless plugging, but it's not just a pitch for Legion. And Curtis is also the co-founder and the former lead researcher and writer for examine.com, which is the premier online resource for science-based information on supplementation. If you're not familiar with examine, go check it out, examine.com and poke around and realize that the majority of the technical, the very thorough to the point of being overwhelming,
Starting point is 00:02:51 a lot of that information, most of that information was researched and written by Curtis over the six or so years that he worked on that project. He personally reviewed over 40,000 papers and wrote hundreds of thousands of words. And I'm only saying that because I'm impressed by it. Curtis knows supplementation inside and out. He's really at like a pharma D level of understanding of human biology and supplementation. So it's always fun to talk about those things with him. So here is a little sneak peek of what you're going to learn in this episode. You're going to learn what a pre-workout is. You're going to learn ingredients
Starting point is 00:03:29 that do and do not work, that do and do not significantly improve performance and muscle and strength gain in particular. You're going to learn how much you need to take of these ingredients to see benefits, the pros and cons of including creatine in a pre-workout supplement. And the reason why I'm calling that out is because it's something I get asked about fairly often. Is it good? Is it bad? And more. This is where I would normally plug a sponsor to pay the bills, but I'm not big on promoting stuff that I don't personally use and believe in. So instead, I'm just going to quickly tell you about something of mine, specifically my fitness book for women,
Starting point is 00:04:05 thinner, leaner, stronger. Now this book has sold over 150,000 copies in the last several years, and it has helped thousands of women build their best bodies ever, which is why it currently has over 1,200 reviews on Amazon with a four and a half star average. So if you want to know the biggest lies and myths that keep women from ever achieving the lean, sexy, strong, and healthy bodies they truly desire, and if you want to learn the simple science of building the ultimate female body, then you want to read Thinner, Leaner, Stronger today, which you can find on all major online retailers like Audible, Amazon, iTunes, Kobo, and Google Play. Now, speaking of Audible, I should also mention that you can actually get the audio book 100% free when you sign up for an Audible account,
Starting point is 00:04:58 which I highly recommend that you do if you're not currently listening to audio books. I myself love them because they let me make the time that I spend doing things like commuting, prepping food, walking my dog, and so forth into more valuable and productive activities. So if you want to take Audible up on this offer and get my book for free, simply go to www.bitly.com slash free TLS book. And that will take you to Audible. And then you just have to click the sign up today and save button, create your account. And voila, you get to listen to thinner, leaner, stronger for free. Alrighty. That is enough shameless plugging for now, at least let's get to the show curtis frank returns what's up man ah not much not much what's the weather like is it cold as fuck up there it's still cold
Starting point is 00:05:52 down here in virginia oh it's really cold now but like this is the good type of cold because cold is the only negative thing affecting us canadians in northern ontario right now because in the past few weeks it was either like every now and then getting just warm enough to also rain and then getting cold right again. Or it was the whole, the wind turns daggers and hurts your face. Yeah.
Starting point is 00:06:15 But right now it's cold, but it's very manageable. Just bundle up, have a scarf over your face and you're good. And stop whining. Yeah. The goose aren't out. So that's good. That's what I was going to say. At least. Always stop whining. Yeah. The goose aren't out. So that's
Starting point is 00:06:25 good. That's what I was going to say. At least the geese aren't hunting for your eyeballs. All right. So now that the chit chat is over, let's get to pre-workouts. That's what we're talking about today. Both thought this would be a good topic because pre-workouts are super popular. a good topic because pre-workouts are super popular. Our Pulse is our best-selling product out of everything. I've written a bit about pre-workouts in the past and spoken a little bit about it, but haven't really had an in-depth discussion, whether in writing or over the audios in a bit. And so here we are. Let's just start at the top, Curtis, with what is your definition of a pre-workout? Okay, so a pre-workout, like my basic definition is something you take before a workout for the purposes of either enhancing that workout or enhancing the benefits you would get from that workout. But that could be quickly or something like maybe beta-alanine that has to well something that like let's say something that is caffeine for example just want to take a coffee before work that would improve your workout so that classifies but then
Starting point is 00:07:32 if you take something like let's say erythritol and have a bit though right like if you're going for a performance boost gotta have quite a bit of caffeine it depends on what you do like or it could just be like a placebo some people just have like 90 milligrams caffeine and that's enough to get them waking up. Yeah. If nothing else, they just feel a little bit perkier in their workouts. And so then they enjoy their workouts more. And so then they apply themselves a little bit more to their workouts and get more out of them. Right.
Starting point is 00:07:56 And anything that comes with rate of perceived exertion of which exhaustion is voluntary, minor placebo effects do go a long way. Yeah. Yeah. is voluntary minor placebo effects do go a long way yeah yeah but like then it also applies to stuff like rachidonic acid which has absolutely no properties proven or theoretical to enhance your ability to work out but it amplifies inflammation from your workout increases DOMS and all that and is thought to increase muscle growth because of it it's not really proven yet, but I would also classify that as a pre-workout because it works best when it's in your body just before a workout. How does that play out in terms of the common ingredients? So let's get more into
Starting point is 00:08:36 the products themselves. So obviously there are a handful of ingredients that are common in pre-workout supplements. They're not all the same. They're not all equal. They don't all benefit you in the same ways. And depending on how you work out, some are going to help and some are not going to help, right? Correct. Because generally speaking, when it comes to how supplements affect the workouts, at least for the scientific studies,
Starting point is 00:08:58 there's like four general categories. The one rep max or anything power related, usually when it comes to science, it's a sprint tests. Although sometimes you see a bench throw as well to just prove max power and anything that works in max power, it would work well for powerlifting, Olympic lifting, or any sort of very dynamic sports training. Okay. that would be what what in terms of rep range what would you say one to three okay so just very heavy like yeah one to three or if it's not necessarily reps like when it comes to sprinting four seconds or less and then it comes to some things where it acts for endurance but only for as long as it's carbohydrate based like glycogen
Starting point is 00:09:43 sort of thing and when it comes to the whole glycogen, carbohydrate-based, anaerobic is the word I was looking for. Wow, that took me way too long to find. Anaerobic training. Like you don't really know exactly where the line is between supplements that help with anaerobic and supplements that help with aerobic. Because if your workout's kind of on the edge, they can both help you.
Starting point is 00:10:04 But some supplements do clearly show better benefits for anaerobic training and some clearly show better effects for aerobic training. When it comes to studies, anaerobic training tends to be weightlifting workouts, whereas aerobic training is just straight up a jog or a cycle for a prolonged period of time. And then the final one is the, how do I say this? It's kind of like the death march for any supplement where almost none of them are successful. A 2K on an erg, like rowing.
Starting point is 00:10:37 Creatine and maybe sodium bicarbonate are the only things that have been successful on that. Everything else in existence has failed. I just kind of want to mention that because like almost every pre-workout you could if you give it to people about to do rowing at a collegiate or like university level the supplement's going to fail there's a limit to pre-workouts and sodium bicarbonate you get to shit yourself after as well out of any sort of supplement where there's a very fine balance of take just this much and not a bit more because otherwise you'll vomit and shit yourself.
Starting point is 00:11:11 You really don't want to take that supplement right before you just exert yourself when it comes to exercise. Because even if you get the dose right, you're going to accidentally hit yourself in the gut once with the rowing machine handle and then just vomit all over it and probably get beat by your coach not if you win though uh if it's during practice you're just going to get beat regardless it's true so you save it for for the big day yeah let's get to some specifics so for the power what are some ingredients that help with that what are some ones that maybe are commonly promoted to help that don't the main three for power based would be caffeine which i'll have to go through some nuance for creatine and alpha gpc creat, I just want to talk about it and get it out there quickly. It's also good for
Starting point is 00:12:07 anaerobic training, but creatine can just help with power. You don't need to take a pre-workout, just have some in your system, bing, bang, boom, done. That's it. For caffeine, it's much more nuanced because caffeine, if you're not used to it, it can act as a dopaminergic agonist. It can actually be a very potent stimulant, as well as having anti-sleep effects. If you become tolerant to caffeine, you no longer feel the stimulant effects, but you still get the anti-sleep effects. The ability for caffeine to increase power is due to the stimulatory effects. And it is very powerful as a power increaser. Something like 15% increase on your deadlifter squat for one rep.
Starting point is 00:12:54 Like that's huge. How much caffeine though? That's the thing. First of all, you need to take it like once every two weeks. That's it. Even just a couple of days a week. Nope. You're going to, you're going to become.
Starting point is 00:13:09 Yeah. Like you can't even have tea at this point. That's it. Even just a couple of days a week. Nope. You're going to, you're going to become like, you can't even have tea at this point. Or if you do have tea, like 30 milligrams or less, like one cup of green tea in the morning, that's it. And then when you're heading into your workout, like, I don't know the exact milligram per kilogram measurement, but last time I checked, I think a 150 pound adult male needs to take at least 400 milligrams acutely. The number that pops in my mind is somewhere around 0.6 milligrams per kilogram. That's the upper end of the range, right? For power. I think so. But the numbers that are like in my head right now is 400 milligrams acutely or up to 600 milligrams for some 250 pound people. For me, I weigh 195 pounds, milligrams for some 250 pound people for me i weigh 195 pounds probably be what somewhere around 550 milligrams four to six milligrams per kilogram body weight in that four to six hundred range around 500 milligrams this is for people who are not tolerant to it yeah so you're gonna be jazzed
Starting point is 00:14:00 is the best way to say it like you may get pulled over and the cops will have you do a urine test just to make sure. That's the type of stuff that caffeine can do if you're not used to it. But it does have power to it. It's one of the best proven ways to increase one rep strength out there. Everybody listening who has caffeine at all is going to be sensitized by now. It doesn't even make sense, of course. You hear that and you go, oh, that's cool. But for the average everyday person who's just in the gym trying to get in shape, does it really matter if they every two weeks can squat or press a bit more weight? Nah, they would rather just have their coffee every morning.
Starting point is 00:14:39 For some people, it does because especially when I was younger, I loved the idea of just abstaining from something for two weeks and then just going balls to the wall on that single day. In fact, I'm thankful I never went to Vegas when I was younger, because it would have ended very poorly for me. It's not too late. It's not too late. No, I don't have the mentality anymore.
Starting point is 00:14:59 My mentality is more moderate, and I do have the caffeine every day approach. But if you're willing to abstain caffeine for a long period of time, then know that it is a viable way to improve your... I mean, if nothing else, it's going to be an interesting experience, right? Yeah. If you resensitize yourself to caffeine and then have that much before a workout, it's going to be the best workout you've had in a long time. That's for sure. And make sure there aren't any cardiac issues leading into that.
Starting point is 00:15:24 Fair point. Good medical advice. But extending from there, I also mentioned alpha-GPC. Just quickly on caffeine, so to clarify then, for those of us having it every day, even if it's not that much, right? So in my case, my average daily intake is three shots of espresso in the morning, and that's it, really. But that's it really but that's enough i wouldn't be able to benefit from any sort of acute power increase by one day doing 600 milligrams before i train or something correct because like caffeine has a weird tolerance usually as you take 200 milligrams something you get tolerant to that level then you increase it a bit more you get some of the benefits back
Starting point is 00:16:03 then you get tolerant to that level again that's how tolerance normally works but caffeine is very much uh putting your foot down like just closing a bunker door type of no soon as tolerance hits it's called an insurmountable tolerance you no longer get those benefits full stop no matter the dose you take. So if you are tolerant to caffeine, you don't get the strength benefits, end of story. But you still will experience more alertness, right? Yeah. The anti-sleep effects are still in effect and there may be some help to the rate of perceived exertion. So when it comes to endurance work, you maybe feel like you're able to get one or two extra reps out each set. But the highly unique boost in power that is kind of amphetamine-like, that's just gone
Starting point is 00:16:53 out the window. So then you just got to do amphetamines. I'm not going to recommend that, but you're on the right track. All right, cool. So let's move on to AlphaGPC. Yeah, AlphaGPC is less researched. It doesn't have nowhere near as good evidence for caffeine, but it appears to be on the right track, appears to be a bit weaker, and it does not appear to have any issues with sensitivity tolerance. You can actually take alpha GPC before every workout,
Starting point is 00:17:19 you might be able to see a small increase in power as assessed by bench throws and sprints. What's a bench throw? I've never even heard of that. So it's a technique that you should do on the Smith machine. Don't do it just with this three bar. Like do a bench press, bring it down to your chest and throw the bar into the air. Hopefully you catch it. You basically put on a set amount of weight and you see how high you can throw it.
Starting point is 00:17:44 One to three reps or maybe do one rep, wait 10 seconds, do one more rep. It's a very power-based measurement of the chest. Sounds kind of fun, actually. Yeah. For me, I like doing them in warm-up sometimes. Like I also do jump squats when I warm up. It's just fun. Well, yeah, I just like hop around.
Starting point is 00:18:02 Tim Ferriss says that they fight belly fat too, so. Oh, no, I just like put a plate on each hopped around like a bunny. Tim Ferriss says that they fight belly fat too. Oh, no, I just put a plate on each side and hopped like a bunny. People just look at me, he's like, oh, whatever. He's doing the thing again, just leave him be. When it comes to just actual making a scientific study, good way to assess strength. Makes sense. And in the case of alpha-GPC then, how does it work? It seems to just get to the brain relatively fast and be on standby.
Starting point is 00:18:28 So when you need to create acetylcholine, which is the neurotransmitter that is used for muscle contractions, it helps mediate how the brain instantaneously causes muscles to contract. It's there to allow more production of acetylcholine. And you're able to contract your muscles more forcefully because of that? The amount of acetylcholine. And you're able to contract your muscles more forcefully because of that? The amount of acetylcholine you have is temporarily higher. So there's more floating around free to work. And if you just did this 24 seven,
Starting point is 00:18:53 eventually your body would normalize and just say like, this isn't a normal condition, desensitize a few things. But when you have a small boost before workout and you're using it, the body is grateful for the situation at the level of a neuron it's thinking we have too much of this neurotransmitter what do we do oh we can just use it that's convenient and then it just does it get bigger
Starting point is 00:19:15 biceps it's similar actually to how creatine works right and that it's similar in that it's a reserve of energy really you know it's increasing energy reserves that you can tap into during your resistance training well acetylcholine does have a sort of reserve within every neuron because you can get depleted acetylcholine just have none left over but acetylcholine itself does not turn into energy it's more the signaling molecule just has insulin hits on the insulin receptor acetylcholine hits on the acetylcholine receptor. So it's the strength of the signal as opposed to the actual energy itself. Yeah.
Starting point is 00:19:49 So if you, for some reason, have no acetylcholine in your cells or a very small amount, it won't be able to send as much of a signal through. And just by having some alpha-GPC, you may be able to attenuate the depletion somewhat or maybe temporary increase. The temporary increase hasn't been 100% confirmed in studies. It seems to increase power and this is the most reasonable theory behind it. Interesting. And how much do you need to take and when to see these effects? A lot of studies use a bunch of different doses. So we haven't really tuned into the... That was part of the problem you ran into
Starting point is 00:20:25 right because we're adding alpha gpc to pulse but there was a question of how much to add exactly and then there's also some other supplements like forge that has cdp choline so we want to make sure that if people are using forge and pulse they're not getting too much choline yeah and then there's also ascend and tropic so yeah because like when you have a study that showed 250 milligrams worked, and then another person has a study showing that 600 milligrams worked, and neither of those studies are actually designed to say whether 250 is better than 600 or vice versa. It's basically you have two data points,
Starting point is 00:21:00 and there's no way to choose which one is better than the other. And when it comes to cholinergics, you could potentially have too much. Yeah. And for people listening, more is not always better. That's not how it always works. Yeah. There are some supplements where more is not better, but you can just throw in more and there's no real downside. For any cholinergic, there could potentially be a downside when it comes to headaches. And in the case of alpha-GPC, it's just horrendously expensive. So we want to get the lowest active and reliable dose possible. Yeah. One of the guys in the office ran into that. The headaches? Yeah. It was Ascend. It was Forge. And I want to say, I think he was also taking the
Starting point is 00:21:39 Stemfree pulse, which already has the alpha GPC added for anybody listening. We are rolling out this new formulation first with the Stemfree because it's a new product and it's easy to do. Pulse, which already has the Alpha GPC added for anybody listening. We are rolling out this new formulation first with the Stemfree because it's a new product and it's easy to do. And we're currently wrapping up all the flavor testing. If we're going to change the formulation, we've got to make sure that we change all the flavors, obviously. So the caffeinated Pulse is a little bit behind the Stemfree. But anyway, so it was a full serving of the Stemfree, a full serving plus probably a little bit of Forge. And I think he was taking Ascend.
Starting point is 00:22:08 And yeah, he started to get headaches. So if we can avoid all the headaches and still have an active dose alpha GPC, that would be perfect. But at the same time, if it turns out in five years that 600 milligrams is the best dose, it's kind of embarrassing to be stuck putting in 250 milligrams in all our products. And we don't also necessarily want to assume that the majority of people who are going to use Pulse are also going to be using a full plus serving of Forge every day. And he might've even been using twice a day because he might've been doing fasted lifting and then cardio later plus Ascend, it's going to be a special case. In most cases, people are just going to be using Pulse regularly, and then they're going to be using
Starting point is 00:22:50 Forge here and there when they're cutting, and a minority are going to be using Ascend. Oh, yeah. It's just something we have to deal with, work out on our own, or my own, because I'm that guy. That guy. And in terms of timing on the AlphaGPC in particular, what is it, 30 minutes before you train? It's similar to the caffeine where it's usually it's 30 to 45 minutes. When that term, like that range is given to you, basically means take it and then get to the gym before the 30 minutes hits. At around 30 minutes, you could be in the zone. before the 30 minutes hits. At around 30 minutes, you could be in the zone.
Starting point is 00:23:27 Some days it could take 45 minutes. You have that 15 minute range. You should be willing to work out, at least start your workout at around that time. Because some days it'll hit you in 30 minutes. Some days it'll hit you in 40 minutes. It's a little bit different each time, just based on what you have in your gut at that point.
Starting point is 00:23:42 Okay. Just out of curiosity, what types of foods slow it down? I used to have a warning list of stuff not to eat, but the main problem would be the mixture of protein, fatty acids, and gel forming properties. Because there's a lot of things that take a long time to digest. Like fibers take a long time to pass through, but fibers pass through the stomach fairly fast. Then they get to the intestines and then they take a long time there. But as long as stuff gets into these small intestines,
Starting point is 00:24:11 who cares if you have like half a steak sitting in your large intestines or your colon, they're not going to meet. So you don't want stuff sitting in your stomach, waiting there and ensnaring anything that comes by. So I personally wouldn't have any dairy before a workout. That's always the reliable caffeine killer for me. Yeah. And of course, like the casein proteins in dairy do have gel forming properties. So if you take anything else there, then the gels could just sort of ensnare and cover the thing and then slow down its absorption rate because it only allows a little bit of trickle into the next area. And what about whey for people listening? I'm sure a lot of people are wondering. Oh, if it's just isolated whey, it's totally fine. No gel forming properties whatsoever,
Starting point is 00:24:56 just kind of zip, zoop, goes right in. Honestly, if you have multiple scoops of whey a day, I would actually consider that a risk factor for diarrhea. That's how well it goes through. And it's also why I pair my whey with Metamucil to prevent that. I mean, I have a few scoops a day, but I guess I eat enough fiber and other foods to not have that issue. Yeah, I just, you know, I like the whole ghost poop cannon kind of thing. Sit down in the toilet, stand up five seconds later, wipe once, done. Those are glorious times. They're're rare that's my morning every day essentially wow that's why i have metamucil every
Starting point is 00:25:33 time i have whey protein i'm actually kind of jealous that's that's the key takeaway of this entire podcast is that yeah like i just like i go out have some chicken wings and beer with my friends or whatever just like talk about standard guy stuff then it's just like i go out have some chicken wings and beer with my friends or whatever just like talk about standard guy stuff then it's just like oh man my back was really hurting did you have your metamucil i had my metamucil bro oh your metamucil makes it pass so good we just sound like old men so good so that's alpha gpc that's it for the power? Or was there another one? That was essentially it for the power. For creatine, caffeine, and alpha GPC. We don't have too many other acute benefits that are legal, at least.
Starting point is 00:26:14 And for creatine, I guess there's not much. And I should also mention that extending beyond the legalities of things, if you happened to have an amphetamine in your hand, and then it was not in your hand because it's going down your throat, yeah, it's going to hit for acute strength. Amphetamine signaling is all for acute strength, not much else. I don't recommend it, but if you ever see someone spassing out of the gym and lifting way more than they should, keep your distance. Amphetamines were big among the Nazis. Maybe that's why they were strong, man.
Starting point is 00:26:44 I don't really know about that. No, it was. It was amphetamines and what was the,is maybe that's why they were strong man i don't really know about that no it was it was amphetamines and what was there was two drugs they were big on so if you take amphetamines before lifting you're a nazi that's basically what that means i actually think the americans use modafinil a lot especially when it comes to their pilots so yeah if you activate the amphetamine signaling you're a nazi but if you activate the histaminergic signaling, you're an American. There's a good snippet. That's a good little quote. It'll be in the bullets.
Starting point is 00:27:10 Here's what you're going to learn about in this episode. Yeah, and if you take it benzo, you're Italian. I can say that as an Italian. I can say whatever I want as whatever I identify as. So I don't have to worry about that. What's even the limit for that? Like saying as a blank like is there a heritage line it was just like i'm one eight this okay you can pass through
Starting point is 00:27:30 i mean teeth no no stay outside the senator warren she was like 1000th american indian and she can say that my high cheekbones yeah but the thing is like at best she was 132nd at worst she was 1064th or whatever but even when you look at the best situation 1 32nd is like no no that's one out of 32 i'm one eighth of something and i'm just like you know that's one eighth that's pretty low like can i even call myself that if i'm one eighth then someone walks in it's like i'm one of a thousand i'm totally legit it's like no you're not no it's it's on the level of gaslighting actually it reminds me of in 1984 where when o'brien was saying basically we tell people ridiculous lies because if we can get them to believe obviously false things ridiculous absurd things we've broken them and we can get them to believe anything and that's what i think of when i see shit like that them and we can get them to believe anything. And that's what I think of when
Starting point is 00:28:25 I see shit like that. Like if you can get someone to actually agree that someone who's one one thousandth at best one 32nd at worst one one thousandth American Indian is a legit American Indian. You can get them to believe anything actually. Yeah, kind of. Yeah. On the topic of gaslighting, I was talking with a few other people earlier and they mentioned something called DARVO. And it's the acronym for Deny, Attack, Reverse Victim and Offender, where basically if you're ever like put against the wall on any sort of topic, you deny that topic. First and foremost, like no holds barred denial, immediately attack before they get any sort of response in. And then even though you were the offender you now play the victim and call them an offender paired with darvo paired with gaslighting
Starting point is 00:29:12 a lot of political rhetoric really sounds like an abusive boyfriend these days or girlfriend true more likely i should mention especially the Statistically, the data shows. I'm going to look that up. I just Googled it. I had not heard about that. But it's one of those things that immediately you go, oh, yeah, that makes sense. And yes, you see it in the political space back and forth. This is now just kind of the modus operandi, it seems.
Starting point is 00:29:42 I mean, you see it on both sides of the political aisle. And I guess there's quite a bit of research on this. So there's obviously psychology underlying this. That it's one of those like shitty things about humans is what it looks like. You know what I mean? Yeah. Like you have to get stuff off your back. So you just throw it off at somebody else and blame them for having stuff on their back.
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Starting point is 00:31:33 All right. Well, getting back on track here, we didn't say this, but creatine is simple, five grams a day. Take it with your post-workout meals if you want to. It's probably the best time to take it. Not that it really matters all that much, but would you agree? Yeah, the timing stuff on creatine, it's weird because theoretically, it should be better when taken post-workout if the other post-workout stuff is all in order. The other post-workout stuff
Starting point is 00:31:59 where you have like carbohydrates flowing through your system, all your cells are ready to actually consume something for the first time rather than just being damaged, taking creatine at that time should be the best. And there have been a few studies suggesting that it's a bit better. Other studies find no real difference. And at this point, I would say that 90% of taking creatine is not time dependent at all. The most important thing is that you just
Starting point is 00:32:26 get creatine in your face at some point. But the timing thing may be better for some of us who are creatine non-responders, where you can take like 10 grams of creatine a day and you don't even gain water weight or barely any water weight from it. Some people, when they take like 10 to 20 grams creatine a day to a loading phase, they gain 10 pounds from that loading phase. Being so like weird in my phrasing this because I don't respond well to creatine at all. And it's because of that that I always take it post-workout because I feel that for those of us who don't respond well to it, I feel that for those of us who don't respond well to it, we need to get any sort of small little tweak, no matter how potentially unscientific it is, just to actually maybe get some of the benefits of creatine.
Starting point is 00:33:14 Do you think a non-response is related to absorption? Because that's really what you're getting. That's the little boost. Oh, the definition of non-response is how there's creatine in your blood vessels. So you absorb the creatine it's just not going into your skeletal tissue technically speaking everybody absorbs creatine from the blood to the skeletal tissue but as a general rule of thumb non-responders absorb like 20 percent or less of the creatine and some people just absorb like 80 percent of the creatine and
Starting point is 00:33:42 the rest just gets washed out, it just like floats around for a bit until it degrades and gets pissed out. So there is something within the muscle cell that is basically saying, okay, we don't need this creatine go away. For some people, they just eat enough meat that they already have good creatine stores in their muscles. For other people, there's like another factor. Nobody really knows if there's like the thing that causes creatine non-response. But despite that, some people like me, no matter what we do, we just don't get much response from creatine. At the end of the day, like if you don't respond to creatine, consider taking it after a workout
Starting point is 00:34:18 with carbohydrates, pretty much anything that can help refuel muscle glycogen. And then of course, a bit of protein, and maybe you'll get lucky and get more into your muscles. No promises though. Makes sense. All right. So that's it for power. Let's talk anaerobic now. Kind of lump them together. I said anaerobic and there's some crossover with aerobic as well. Yeah. From one category to the next is always going to be crossed over. Like creatine is the first good example. It does increase one rep max, but because it uses the creatine phosphate system for that one rep to help that one rep go, indirectly spares some muscle glycogen. So usually because of this, if you're doing any work in like the six to 10 rep range, you can usually get an extra rep out of it when you're using creatine. And that's essentially all it is for creatine. There's nothing impressive.
Starting point is 00:35:12 It just indirectly spares a bit of glycogen and you get an extra rep. It's reliable, it's cheap, but it's not really that pretty. Actually, citrulline is a good one to bring up because I still don't know how it works. That's a good way to start. It's good, but who knows why? Yeah, because if you think about it, citrulline increases nitric oxide, so it helps with blood flow. You get more blood flowing. Yay. Maybe you get some more nutrients circulating around. Yay. How does that increase muscle growth?
Starting point is 00:35:42 How does that increase muscle endurance? How does that increase muscle growth? How does that increase muscle endurance? The last time I checked, when you were working out and you got lactic acid in your muscles, it was in your muscles. It wasn't in your blood. So what the heck's happening there? Anything that increases nitric oxide can potentially also give you an extra rep in the 5 to 10 rep range.
Starting point is 00:36:05 And citrulline is one of the most reliable ones because it's better absorbed than L-arginine. Nitrates from leafy green vegetables are also an option here. It's just they're not the best supplemental option because of legalities around sodium nitrite being added to pink meats and all that. You could pound some spinach before you hit the bench. Any leafy green to be honest just shoved in a blender blend it down be judged by your child for what you're doing and just drink it and go to the gym force them to drink it too but we actually hide spinach
Starting point is 00:36:35 in fruit smoothies for our kids you are like a dictator in your house that's even we've even hidden spinach and pancakes but that stopped working when the green hue threw my son off. He did it for a little bit. He wasn't going for it anymore. You need to put a nice little layer of Nutella on top. Look at the chocolate pancake. Don't flip it. It's like pure broccoli.
Starting point is 00:36:57 Knowing him, he would figure it out. He's a con man at heart. Just like his dad. Yeah, more money. I don't really know how the nitric oxide stuff's working, but it seems to be. But the bottom line is, yeah, citrulline is a reliable increaser of muscle endurance, right? Yeah. And it may actually increase muscle growth over a long period of time because nitric oxide does increase a satellite cell recruitment. It sounds more fancy than it really is because every now and then
Starting point is 00:37:26 there's going to be a few listeners who have never heard of a satellite cell before. And now they're Googling it and they're going to be in like a little rabbit hole for the next few hours. Satellite cells are cool the first time you hear about them, but then they get boring.
Starting point is 00:37:39 Anyone listening, if you want to learn more about that, but not spend hours in a rabbit hole, just Google muscle for life hypertrophy, hyper trophy, and you'll find an article I wrote on that that was updated semi-recently that goes into some of the mechanisms of muscle building and explains in simple terms what satellite cells are and how they relate to muscle growth and so forth. So citrulline, effective dose, timing?
Starting point is 00:38:06 Effective dose, we use eight grams. I'd be okay with six grams, to be honest. It's a little bit less, but not by much. And I would actually recommend taking it around the 30 to 40 minutes before workout. Same with the other ones. But know that it may hit you later in the workout rather than your first set.
Starting point is 00:38:26 So good. You get your warmups done, and if it hasn't hit you already, it'll be revving you up for your hard sets. And by the way, if people are listening, when he says we, he's referring to Pulse, which is the pre-workout that he designed, and that's Legion's pre-workout. Pulse is 8 grams of citrulline in it. It tends to be the higher dose citrulline has kind of a tart flavor to it so some people don't like it others not so much they like them we are improving in that regard i mean i think pulse has always tasted okay some flavors more so than others i actually like tart so something like green apple i've always really liked but with this update to the formulation, we are also working with a
Starting point is 00:39:06 different flavor lab that is just better. So I think we've improved every flavor actually. I'm excited to get all of these guys out there and get some feedback. And moving on to another one, beta alanine. I will be honest, a lot of people say that it's creatine 2.0 and i don't understand what they're smoking like have you heard about that people just hyping up beta no okay because like is that a more recent thing that's more old than anything it's been around for like five years people hyping up beta alanine more than it should be its entire purpose is if you've heard of the amino acid l alanine or just alanine you just twist one little thing around into a beta
Starting point is 00:39:47 configuration now it's beta alanine that's quite literally it nothing special when it combines with histidine it turns into carnosine and carnosine is something that's in your muscles floats around it just sort of scavenges stuff that could make your muscle inefficient you always have carnosine in your muscles it's always working sometimes you don't have enough and your muscles fatigue because you're lacking in carnosine. Beta-alanine supplementation is a good way to get it into your muscles because if you take carnosine by itself, it needs to break down to beta-alanine and histidine anyways before you take it into the the muscle and so by increasing stores of carnosine it doesn't provide energy but can help with cleanup and unlike the things that we mentioned
Starting point is 00:40:33 previously that help in the five to ten rep range beta-alanine is very strong in increasing endurance in the two to three minute rep range. So any sort of cardiovascular stuff that takes multiple minutes to do, beta alanine could help you with. When it comes to standard, you know, workouts where you just do 10 reps and then you rest for a minute, beta alanine is probably not going to do much. And just as a side note, I actually do German volume training a lot, not going to do much and just as a side note i actually do german volume training a lot which is you do 10 reps you wait for 20 seconds you do 10 more reps you wait for 20 seconds you do this until you do 10 sets it's quite literally 10 reps of 10 sets with 20 seconds rest in between or you die whichever one comes first yeah either or. Germany has no place for the inefficient. Or the weak.
Starting point is 00:41:25 We already know that. But beta-alanine seems to work for that, in my experience. So it seems to be the whole, if you're doing a lot of work and you're not giving your muscles time to relax and get blood flowing back to them, you want beta-alanine. But if you're doing a standard workout, then despite beta-alanine being in a lot of pre-workouts, may not help you if you take sufficient rest between sets. And there's also the potential muscle building effects, right? There's evidence, but it's not quite understood why that would be. Yeah, we don't even have any leads on that. We've just found that there's some studies where you have group given placebo,
Starting point is 00:42:06 group given beta alanine, and these groups do the exact same amount of workload, have the exact same amount of food, and the beta alanine group has a bit more muscle. Nobody knows why this is the case, but it could theoretically help build muscle, even if it doesn't help you in your workout. It's good to slip into something. And the tingles are great. I like them. I'm weird. The tingles are so good. I mean, I take niacin, I forgot to take it today. I take it semi-regularly just because I like the flush. I told you this before, but for any listeners, the first time I ever felt the niacin flush was before I actually knew what niacin did. and I thought I was having an allergic attack and overreacted horrendously so now I don't like that particularly maybe it poisoned the well maybe it's like you know when you eat a food and then you get food poisoning and you can't eat it
Starting point is 00:42:54 again for for a long time yeah like whenever I feel that particular type of flush because it has a lot of cheek warming to it then I just kind of panic a little bit. But beta alanine has no cheek warming. It's just all tingles. With niacin, sometimes I almost get like a niacin high. There's like a euphoric effect. I don't know why. Yeah. I tried to look into that after you mentioned it earlier, but I couldn't find anything on that. I mean, it's reliable. It doesn't happen every time. It's more likely to happen if I don't take it for a bit and then i take it could be 500 milligrams like a higher dose where i get a kind of intense flush yeah it ends with the euphoria i'm scratching myself or i'm rolling around on the carpet like a weirdo it just feels
Starting point is 00:43:37 good man that's my version of drugs man i need a vice i don't have any real vices so i need something i take niacin every once in a while to anyone uh listening when it comes to uh do those little niacin experiments they should be safe unless you overdose on it each and every day and of course like even though there is like overdose so to speak like just to uh get the flush like this you will need to go over the rda but you know you can go over the rDA to a certain limit without hurting yourself. So it appears that when it comes to niacin, you can take a gram a day, and it doesn't seem to be too bad. If you take two grams a day, most cases it doesn't have any harms to it, but that is the dose of which some people started to get negative effects.
Starting point is 00:44:23 And around five to six grams a day is when the negative effects start to become more common. Yeah, I've never gone above a gram a day. And again, it's not every day. My brother-in-law is even more into niacin than I've ever been. I think he was up, you become tolerant to it, right? So you have to take more and more
Starting point is 00:44:40 to continue getting any sort of significant flush. So I think he got up to five grams a day for a while until I told him, but I didn't know he was doing it until he mentioned. I was like, nah, that's too much. You need to stop. So to reiterate those doses, one gram seems to be okay. Oh, I don't think I'd recommend a gram though to somebody who's never taken it before. I think that's going to blow them. Oh, true, true, true. It's because you can get really nauseous if you don't build up to it. It's probably for the average person, what, 100 milligrams might produce a flush?
Starting point is 00:45:11 1, 200? Might be a good starting point. If it doesn't give you a flush, then oh no, you missed out on a single flush, take another pill. Starting low always helps there. Let's just try to sum all that up. And as far as any sort of benefits, it can benefit your cholesterol levels, right? That's about it. Only the ones that give you the flush, because niacin gives you the flush. Niacin,
Starting point is 00:45:32 nicotinamide, I believe is pronounced, does not give you a flush. Both of them are B vitamin supplements. So they can both actually help with B vitamin requirements. But only the one that gives you the flush helps to reduce cholesterol and it's actually very potent in doing so so that's great news because if anyone's listening to this thing i'm like i want to try a little bit with nice and flush it's like is it safe for high cholesterol it's double good for the high cholesterol very nice i think you'd also am i making this up there's something like you'll get better pumps if you don't mind looking like a weirdo in the gym with because you're gonna get red and splotchy
Starting point is 00:46:10 you're gonna look like you have a disease i've never tried that actually i think there was something to that i might just be making that up though i'll probably look into it but you know it's worth a shot nice and cheap for any women listening it'll keep guys away from you they won't come bother you. You just growl when they come near as well, like right in the face, sweating. Oh, ma'am. Scratching yourself. Like you're just broken out in hives, sweating, scratching yourself, grumbling.
Starting point is 00:46:39 That'll keep guys away. And speaking of tongues, of course, just wrap up the entire package with some Latin. I like it. I like it. Some evangelism woven in. All right. Well, that's niacin, but we were talking about beta alanine. So it has some possible muscle building effects, kind of additive addition to any of the performance enhancing effects, dosage and timing on that. Dose we have in pulse is considered quite hot. Yeah, currently the caffeinated has five grams. And that was part of what we're updating to the formulation. We're bringing that down to 3.8, right? And Curtis, you can explain why.
Starting point is 00:47:14 And then we're adding alpha GPC, which is going to make for an all around better product, I think. The doses range is usually 2.4 to 4.8 grams. And you can't really prove that 4.8 is better than half the dose at 2.4 but if both doses seem okay and you're aiming for like higher intensity athletes tends to be a bit cautious throwing the higher dose unless you have a reason not to and initially we didn't have a reason to because the tingles hit you equally the same. And you know, a lot of people don't really like the tingles. So going down to 3.8
Starting point is 00:47:51 is beneficial in that regard too, where you're not going to miss out on any of the benefits of the supplement and it is going to produce less tingles, which some of us are not happy to hear, but most of the people listening probably would be happy to hear that. So as long as it's effective, we keep it in, but we reduce it a bit. We started out at just an obscenely high dose. I very much enjoyed those times. Did it hit your butthole? Did you get the itchy butthole? Dude, what? That's Arty. One of the guys in the office i have never had an itchy
Starting point is 00:48:28 butthole from beta alanine from beta alanine oh that's arty in the office that was his complaint every time he'd take it like oh my asshole is itching man maybe he was covering maybe he was covering for something else you know yeah there's something else and it's like well if it's itchy blame beta fucking beta alanine yeah meanwhile he's just like. It's like, well, if it's itchy, blame beta alanine. Fucking beta alanine. Yeah, meanwhile, he's just like eating dinner at a new Mexican restaurant, mixing beta alanine with all these freaking hot sauces, just like earning so much money from my game. Or something else. We live in the Washington, D.C. area, so you never know.
Starting point is 00:48:59 As a Canadian, I don't know what you're insinuating, but I don't want to know, so shall we move on? An American worse is worse than Canadian. Probably. All right. So that's beta alanine. What about betaine? Was that on your list?
Starting point is 00:49:13 Do you want to talk about that? Yeah, that's one of those ones that I'm not sure how to pronounce. Like that's the downside of being mostly trained online. I don't know whether it's betaine or betaine. Yeah, it might go. I'm trying to remember because when I was rewriting my books for men and women, I was hitting a bunch of pronunciation websites. And I think Bteen is at least generally accepted as not.
Starting point is 00:49:35 Well, at the very least, I have learned that people don't judge you too bad for it. Pet peeves that people have. If you mispronounce hypertrophy, people are going to flame you for it. Like really smart professor have like you miss if you mispronounce hypertrophy people are going to flame you for it like really smart professor like really old and wizened comes into the lecture hall and this is the neurotransmitter acetylcholine and it's like no no that's not it shame shame yeah after a certain point you're just like whatever Let him have his acetylcholine. We'll have our acetylcholine. Tomato, tomato.
Starting point is 00:50:09 Tomato, tomatioto, something. Tomatioto. Just let them have it. You do it in the accent, then it's okay. Tomatioto. Tomatioto. But yeah, so when it comes to betaine, it's kind of like carnosine in the sense that its entire duty is to mop stuff up and but instead of the case of mopping up stuff within a muscle cell
Starting point is 00:50:31 it tends to mop stuff up more in the blood methyl groups is tend to what happens like just mops up a few methyl groups here and there and it's really boring but it seems to work fairly well in the same time range that beta alanine works in the two minutes or longer of endurance you have about three grams of betaine at minimum for more endurance stuff you may need to go up to five to six grams and it just seems to be a very light increase in endurance does really seem to It does really seem to influence the rate of perceived exertion. So you're probably going to feel just as bad, maybe a little bit more exhausted, but you just do a bit more work. It's just one of the more boring supplements, but it's solid, reliable, and it kind of works. And taurine is similar, actually.
Starting point is 00:51:23 There was a point when you wanted to add ta to pulse and then you change your mind well if they both do the same thing then why have both sure true yeah the main issue is that they don't like technically do the same thing they just have the same results like one goes down road a one goes down road b but they still go to the same store and we only need one thing bought at the store. So let's go for one that's cheaper and more reliable. Makes sense. And there's some evidence that betaine, I'm just going to say it my way, increases strength as well. Am I off there? We referenced that research on the sales page of Pulse, which for anybody listening, Curtis, I write the sales pages, but often I'm going to Curtis to clarify technical points or sometimes even get some copy that I play with.
Starting point is 00:52:05 He goes through them just because I want to make sure that everything that is being discussed and claimed is that I'm understanding things correctly. So the studies do exist. And if someone wanted to call Betain a strength enhancer, they could technically do so. I'm just a bit skeptical of those studies because they were increasing strength reported from endurance work. If you could do 11 reps instead of 10, of course, you're going to be stronger than the 11th rep because the other team didn't have a value to it. The studies weren't that disingenuous. They weren't disingenuous at all. But what I want to call something a strength enhancer, I want the study to be designed strength measurement.
Starting point is 00:52:42 I remember when I was writing that copy. I want this study to be designed strength measurement. I remember when I was writing that copy. I mean, for me, I would say, I mean, you can call that strength. That's how many people would probably think of strength. Oh, if I got 11 reps instead of 10 reps, I got 10 reps last week, 11 reps this week. I'm a little bit stronger. That's how they would think of it, you know?
Starting point is 00:52:59 Yeah, it makes sense. Because power usually has a speed component there. But strength is just the overall overall I do more thing. The reason I don't want to straight up call Betaine a strength enhancer is because if I did that based on the study Betaine has, I might have to call Ashwagandha and Spiralina strength enhancers as well. Buzzwords. Well, because Ashwagandha has two studies of which they just measured grip strength in men. You just have people, they squeeze something, you give them ashwagandha, they come back later, they squeeze the same thing, they squeeze harder with ashwagandha versus placebo. Same thing has happened with spirulina.
Starting point is 00:53:36 Seems sufficient evidence to call it a strength enhancer. It doesn't feel right to call it a strength enhancer when on the topic of sports supplements because it was a group test. Yeah, exactly. That feels a bit slimy to extrapolate that to the gym and just tell people like, oh yeah, you're going to squat more if you take these two. And I'm pretty sure like one of the ashwagandha studies was done in like 60 year old men, but the other one was actually done in youth, which surprised me because I thought the old men would get the strength boost and the young men would not but
Starting point is 00:54:05 they both did so it's one of those things where there may actually be something going on that is benefiting you in the gym if you take ashwagandha yeah it's just how best to measure and yet it did have one study showing an increase in uh sprints so yeah maybe it's actually a strength boost was that was that for ashwagandha or was that for ashwagandha okay spiral leaders literally only had one grip study ashwagandha's had a few spiroglia? Ashwagandha. Spiroglia has literally only had one grip study. Ashwagandha has had a few other exercise studies on it. It makes me think of, these are just little interesting questions. They would be fun to fund research on, gain insight into.
Starting point is 00:54:38 Oh, first study is definitely creatine and hair loss. Oh my God. We're going to do it. People listening are already in talks. So currently we have put money into a lean bulking study that is being conducted by Eric Helms, James Krieger, and a few of the people on Legion's scientific advisory board. So that's underway. And I want to really just put aside an amount of money, have a fund from Legion that I can use for funding research that I think there'll be two lines of research. One will just be research to benefit the body composition space, I guess you could say, or bodybuilding space,
Starting point is 00:55:10 just kind of give back to the community, so to speak. And so the lean bulking study is a good example of that, where it has nothing to do with selling a Legion product, or there's nothing that's going to come out of it other than maybe some goodwill where people, if they know, oh, Legion funded this research, this is good research, and it helps lend some insight into something that's one of those questions that a lot of people ask and that a lot of more scientifically literate people wonder about because there isn't much research on, or at least much well-designed, well-executed research on the effect of a small or moderate calorie surplus on muscle and strength gain. So similarly, the creatine and hair loss research would be along those lines too,
Starting point is 00:55:51 which would be, I'm very interested in putting together and Curtis and I are talking about that. And then we also could look at doing research on individual ingredients that, and again, I would just really tap Curtis's vast wisdom here because there are certain ingredients that, and again, I would just really tap Curtis's vast wisdom here because there are certain ingredients that Curtis believes have good potential, but the research is just not there yet. Or maybe there's some animal research or some mechanistic research that says, hey, this might be pretty cool, but somebody has to come along and put the money up and do the work to see what happens in humans. And so that's something we're going to be getting more into. Realistically, I'm talking with Menno right now because he and Andy Galpin are putting together a lean gains intermittent fasting study that I'm definitely going to give protein to,
Starting point is 00:56:34 and I'm looking at giving some money to. But as far as putting together a larger amount of money, probably going to be later this year or next year, but I'm excited for it. I think it'll be fun. Oh yeah. I'm definitely looking forward to that study. It's been a while since I've seen Menno like hop around, like all happy like that. He's giddy with the thought of this study. It sounds like it could be interesting. I mean, the idea of the study for people listening is because a lot of intermittent fasting research has been conducted with sedentary people, which is cool, but he wants to conduct this research and it's a lean gains protocol with resistance trained people and really look at muscle building and how he sees it is have it be like the definitive study
Starting point is 00:57:13 on the lean gains, intermittent fasting approach for people who are into body composition to say, yes, here it is. We know it is more beneficial or it has some unique benefits over traditional dieting or no, it does not. And really kind of open up. If it does, then it opens up a different, you could say more legitimate line of IF research for us in the fitness space, at least. And they're going to be measuring a lot of the cellular parameters as well. mTOR being the easy one. Is there going to be muscle biopsy or not? I don't think he mentioned. I know it's expensive though. I think the all-in cost of the study is going to be somewhere around 75K. I want to do an acute and then a long-term.
Starting point is 00:57:54 So acute study, long-term study, more than just measuring waist circumference and weight kind of thing. And not like the whole caliper measurements of body fat either i would leave it to meno to have one of the more reliable forms of body fat measuring by calipers but you know beta alanine i don't think we mentioned the timing on that basically it doesn't matter right yeah that's surprising beta alanine's timing does not matter so if for some reason you cannot work out with the tingles you don't need to take it before a workout. You can take it with meals. And when you take it with the meals absorbed at a slower rate,
Starting point is 00:58:30 you don't get as much tingles. But because it gives you the tingles, so many people took it before a workout anyways, because it just got them excited for the gym. Maybe it almost, that's one of the reasons why so many of us like it. It's like a positive association, right?
Starting point is 00:58:44 It's like a trigger. Like the tingles have kicked in. It's like a positive association, right? It's like a trigger. Like the tingles have kicked in. It's time to work out. Yeah. And like, if you just stay in the locker room, running around in circles saying the tingles, the tingles, the tingles, the tingles, security is going to be escorting you up pretty fast. Or not. It's a gym.
Starting point is 00:58:56 They might understand. They'll be like, oh. This is a lot of white powder on the bench. It's just like, I swear it's beta alanine. I swear. All right, cool. So that's beta alanine. I don't All right, cool. So that's beta alanine. I don't think there's anything else to say on that. Was there anything else for anaerobic or
Starting point is 00:59:09 aerobic that you wanted to talk about? The only thing I want to mention finally was just a very brief touch on nitrates because they're not a supplement. They're leafy greens and all that. But when it comes to 10 minutes or more exercise, so, you know, just jogging, there is, by studies on nitrates, evidence that just increasing leafy greens and other vegetables in your diet can improve aerobic capacity. So if you're a jogger, if you just want to run for 30 minutes a day, leafy greens can actually improve your performance because of studies on nitrates. Leafy greens can actually improve your performance because of studies on nitrates. A lot of people always talk about leafy greens and they just say, whatever is green, shove it in your face, do as I say, peasant. And they never explain why these things are beneficial.
Starting point is 00:59:57 But because of nitrates, we've now made that link. Leafy greens can help aerobic exercise because they're a cheap and effective way of getting dietary nitrate into your body. It's a sexier sales pitch because they're healthy. Yeah, pretty much from the dietary side of things. And for a long time, it's like eat your broccoli. Why? Because we said so. We're associated with the government. Don't defy our food pyramid. It's like, okay. It's one of my pet peeves. People's telling others to eat vegetables and never explaining why. If you have kids, I want to see how you go about it. I want to see you explaining nitrates to your five-year-old.
Starting point is 01:00:29 Good luck. Well, if you put this in your mouth, you'll grow strong like daddy. Otherwise, you need to clean your room. Yeah, that's... And then they clean their room anyways because daddy's a mean person. I read about a study recently that had kids do some sort of task that was not enjoyable. And they also had the option to go mess around on an iPad or something. And one of the groups was told to think of themselves.
Starting point is 01:00:56 Just think of the concept, I'm doing this. Another one was think of themselves in the third person. So in my son's case, Lennox is doing this while they're doing the not fun task. And then the third group was to think of themselves as Batman. And the Batman group did the best by a significant margin. You could try that in the gym. Just think of yourself. I will eat vegetables. Yeah. Batman can do it. that's actually a really cute study yeah i'm reading this book on how to make your kid a money genius or something i'm getting ahead of
Starting point is 01:01:31 the curve so i don't have financially illiterate children that are trying to live off of me for their entire lives it was mentioned in that book supplement wise uh is that it i think that's both we cover all the good stuff in the pre-workouts the only last thing we mentioned is just like standard warning against the stupid herbs that appear in the pre-workouts and how they're probably cover for lacing things in it so explain this is kind of like a how to detect shitty pre-workouts right this is important because pre-workouts on the whole, I don't actually know. I mean, protein is definitely the number one bestseller as far as supplements go, but in sports nutrition, pre-workouts are going to be up there. They're very popular
Starting point is 01:02:13 and there are so many options and so many new options hitting the market, making so many different claims. And there are a lot of shady things, a lot of shenanigans in the pre-workout game because you can buy whatever you want from China and it can be laced with whatever you want. And then you can find unscrupulous manufacturers who will bottle whatever it is that you are sending from China without testing it. They don't care. They'll put it in a bottle for you. It doesn't matter what it says on the label. And that can be sitting on the shelf anywhere. One of the reasons why I want to mention the herb issue is because of all that aforementioned,
Starting point is 01:02:52 they can just get random stuff and put it in your bottle and whatever. It happens. But when it comes to something like citrulline, you have L-citrulline. Maybe you have L-citrulline malate. You know what the molecule is. You can google it. You know everything about it. But when you're given a random herb name and you try to google the herb you don't necessarily get clear answers as to what is in the herb or why it's working. And I was talking with somebody earlier about what I consider ethical labeling laws when
Starting point is 01:03:23 it comes to herbs, because you can't list everything of the herb. Like every plant has well over 200 different known molecules in it, but they're all just way too minute to care. But you have an estimate about what works the most. So if you see something like Tribulus terris, and then in brackets, 40% steroidal supponents, that's a good enough indicator of what's inside the plant and a good enough indicator of its concentration. But when it comes to pre-workouts, they, well, I say they, but other people in the industry don't necessarily take steps to elaborate on what's in their products.
Starting point is 01:04:02 This initially happened, well, I wouldn't say initially. The one that I remember most was the Jack 3D product. The old pre-nerf one, right? Is it still around, but now it's just whatever? It's still around, but it no longer has 1,3-DMA in it. But when it first hit the market, it had 1,3-DMA in it. But its label said geranium. Geranium is the family name of a plant.
Starting point is 01:04:27 If you were to name a plant, you'd be like Tribulus terrestris. Tribulus is the family name, terrestris is the species name. If I just said Tribulus, I could be mentioning any Tribulus plant. When it came to geranium, there was over 700 different plants that could have been named. When it came to geranium, there was over 700 different plants that could have been named. The company never specified which of the plants it used. So this made people have to go out and analyze each and every one of the plants for the compounds found in JAK3D to see whether or not this 1,3-DMA was approved by the FDA or not. was approved by the FDA or not. Because according to the FDA, if it exists in nature in an unperturbed form, it's legal and has to be retroactively banned. But if it's outright synthesized, it's not legal from the outset. So after about two years, it was found that 1,3-DMA was completely illegal, should never have been sold. And the only reason it went this far was
Starting point is 01:05:26 because they never listed 1,3-DMA on the label, never mentioned the herb that it was from or supposed to be from, because at the end of the day, it wasn't actually from a plant. And after those two years, the initial people behind that company just cashed out and ran. Yeah. I mean, that was the same company that was caught putting Prozac in their fat burners along with something that was causing liver failure. Yeah. There are a few people. Didn't one of the founders go to jail along with one, the guy who ran one of their manufacturing facilities? Pretty sure some people went to jail over. I do recall like that around the time that they were caught in usp labs like
Starting point is 01:06:06 initially tried to book it but these people had like multiple runs before usp i didn't know that i mean i know that according to court documents it was some insane amount of money was like 400 million dollars over the course of four or five years uh with from just a few other products well there's just some people in the industry who do the entire thing where they make a company, do something with it to make it really popular for a short time. And I'm only saying do something to not put heat on my back.
Starting point is 01:06:33 The something may or may not be related to lacing the first line of supplements with drugs to make people's self-reports go, oh, wow, this stuff is really good. And then they take it out before they can get busted by the feds. They could just be completely innocent on the drug side, but pay way too much money in marketing and just dominate the online area through a forced monopoly. They just bought it and went off.
Starting point is 01:07:00 That's hard to do. I mean, it can be done, but it's hard to do to that level. Talking about that much money, I remember, I mean, you remember when Jack 3 was, it was word of mouth is what drove it because people are all working out in the gym and people always know other people in the gym, even outside of the gym who are into working out. And it's naturally a social setting. And so I remember that's how I heard about it. Somebody told me gym like when i saw i first heard about it said this shit is crazy you gotta try this well i guess i was being a little bit naive because i wanted to give these companies an out saying hey i'm not accusing all of you of spiking your shit with drugs but let's be practical that's usually how this stuff goes yeah spiking the first round and then either leaving it in or taking it out before the feds get you or not like crazed with driven sports and fuck it just leave the amphetamine in there yeah they just left it
Starting point is 01:07:51 i still don't know how they went for so long with that yeah and he already previously was busted for selling um was it dnp yeah for selling i think it was dnp yeah that's the acronym right it's a very powerful fat burning drug oh dn yeah dnp nitrofenol yeah yeah it's extracted from dynamite right and if you take too much you die that's the problem if you take enough it can help you get shredded fast and the worst part is that there is a small demographic of people that may be hypersensitive to it but we don't know because turns out you can't really judge hypersensitivity in humans when you propose to the ethics board, oh, some people might just straight up die. Once that process begins, there's no stopping it either. If you overdose on it, you could go to the hospital immediately and say, this is what I took.
Starting point is 01:08:40 And they'd be like, say your goodbyes because that's it. You're done. The dude who was the CEO, I think it was Matt something in the name, the CEO founder guy of Driven Sports, was already previously busted by the feds for selling DNP as just like fat loss pills. I think he was also, was he also busted for steroids? Possibly. The supplements, scumbags, I'm getting them mixed up in my head. Maybe. I don't know if steroids were involved. Steroids are usually involved with these guys, but it was definitely DMP previously. And then the meth analog in crazed. And I remember when that was getting popular, people were emailing me.
Starting point is 01:09:13 It was the Jack 3D craze again. It was, this stuff's amazing. You got to try it. And then there are people who are asking, who are a bit more informed, how is this possible? I mean, look at the ingredients. There's basically nothing in it. It was some caffeine and maybe another stimulant and some creatine. It was super underdosed, but they were saying, I feel really good. I have really good workouts. And at the time, I was more naive. This was early on in my foray into the fitness space.
Starting point is 01:09:40 And so I was like, I don't know. I mean, it's just maybe these people have never had caffeine before or something, or it's just complete placebo. But no, it can buy them time. And sometimes they're, as we were mentioning, like pretty significant and dangerous things. Other times they're just not so dangerous things, but they technically shouldn't be sold. Or they may be stuff that's completely okay to be sold, but it doesn't just have a good reputation because it has no studies on it. It's like, why did you put this in? Oh, because it causes fat loss.
Starting point is 01:10:28 Can you prove that? And they can't. They just put it in there because they know it gives them a buzz and they don't want to deal with people asking questions. Any pre-workout that uses a herb should go out of its way to give as much information on the herb as possible. And any pre-workout that gives little information is probably hiding shit behind the plant.
Starting point is 01:10:48 It's a good takeaway. Practical. I like it. All right. Well, that I think wraps up our exhaustive discussion of pre-workout. So that was everything we had in the outline at least, right? Yeah. Cool, man.
Starting point is 01:11:00 Anything interesting that you want to share with all of your adoring fans? Nothing at this point in time, although I am getting a bit more back into aromatherapy. Well, yeah, because studies on aromatherapy, by design, they can never be top tier evidence. So it's a bit unfortunate because of that, because you can almost never do a completely perfect blinding of somebody. Is that shit or lavender? I'm not sure. There's no placebo, like no true placebo. There's almond oil as an act of control because apparently almond oil is something that you
Starting point is 01:11:34 smell, but you can never really define what it smells like because it's like, it smells like a smell, kind of a boring smell, that kind of stuff. I know I was suggesting poop as a control but oh yeah poop's probably pretty active but yeah i've had a mustache for quite some time and in the past i used to dab a bit of lavender on the mustache just so it stays in the hairs right under the nose and i get like a continuous waft of the smell as i'm working on my computer and i've started to get back into that mostly when when it comes to beard oils and such, because as long as there's aroma in my beard, I could be actively under the effects of aromatherapy. So I thought like, what if there
Starting point is 01:12:13 was a cognitive boosting one? Or what if there was one that increased alertness? I just put this into my mustache and beard and boom, go. And have you noticed anything? So far, no. no actually i have noticed that having a beard that smells of lemon for over an hour is infuriating do not do that so maybe it's ergogenic maybe you do that before a workout then tap into some extra rage for those croc rows yeah fucking lemons for those crock rows. Yeah. Fucking lemons. All right. Well, thanks again for taking the time, Curtis.
Starting point is 01:12:50 As always, it's fun. And we'll line up the next one. I guess it's also worth mentioning you've been putting a lot of work into updating existing formulations and working on new formulations. I'm excited for that. They're turning out a lot more elegant and hopefully, I wouldn't say cheaper,
Starting point is 01:13:05 but we can slip a few more goodies into them while maintaining the price is what it seems to be happening so far. Yeah. And that's the goal. I mean, we can leverage economies of scale to bring down our costs to some degree. Unfortunately, it doesn't scale that well in this space because good raws are just expensive and good manufacturers work on, I'd say tight-ish profit margins. So an expensive product is always going to be expensive, but it's like reducing the beta alanine impulse from 4.8 to, I think it's, is it going down to 3.6? Is that? At this moment in time, yes, there might be some changes, but it should be at 3.6. Yeah. Which makes sense from an effectiveness standpoint. You're not going to lose any effectiveness. And then it also reduces the paresthesia. It reduces the tingles. But instead
Starting point is 01:13:54 of just leaving it at that and saying, hey, it's still actually an expensive product, but we can make a little bit more. We're taking that money and rolling it into alpha GPC, which is just an expensive ingredient. So we're looking for opportunities to do similar things in other products. All right, man. Well, that's it. We'll brainstorm our next episode and get it out in the next month or so. See y'all later. episode and found it interesting and helpful. And if you did, and don't mind doing me a favor and want to help me make this the most popular health and fitness podcast on the internet, then please leave a quick review of it on iTunes or wherever you're listening from. This not only convinces people that they should check the show out, it also increases its search
Starting point is 01:14:40 visibility and thus helps more people find their way to me and learn how to build their best bodies ever too. And of course, if you want to be notified when the next episode goes live, then just subscribe to the podcast and you won't miss out on any of the new goodies. Lastly, if you didn't like something about the show, then definitely shoot me an email at mike at muscle for life.com and share your thoughts on how you think it could be better. I read everything myself and I'm always looking for constructive feedback, so please do reach out. All right, that's it. Thanks again for listening to this episode and I hope to hear from you soon. And lastly, this episode is brought to you by me. Seriously though, I'm not big on promoting stuff
Starting point is 01:15:23 that I don't personally use and believe in. So instead I'm going to just quickly tell you about something of mine, specifically my fitness book for women, thinner, leaner, stronger. Now this book has sold over 150,000 copies in the last several years, and it has helped thousands of women build their best bodies ever, which is why it currently has over 1,200 reviews on Amazon with a four and a half star average. So if you want to know the biggest lies and myths that keep women from ever achieving the lean, sexy, strong, and healthy bodies they truly desire, and if you want to learn the simple science of building the ultimate female body, then you want to read Thinner, Leaner, Stronger today, which you can find on all major online
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