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At this moment of inflection in technology, co-hosts Elad Gil and Sarah Guo talk to the world's leading AI engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? “No Priors” is your guide to the AI revolution. Email feedback to show@no-priors.com. Sarah Guo is a startup investor and the founder of Conviction, an investment firm purpose-built to serve intelligent software, or "Software 3.0" companies. She spent nearly a decade incubating and investing at venture firm Greylock Partners. Elad Gil is a serial entrepreneur and a startup investor. He was co-founder of Color Health, Mixer Labs (which was acquired by Twitter). He has invested in over 40 companies now worth $1B or more each, and is also author of the High Growth Handbook.
166 episodes transcribedBiohub started with an ambitious goal of curing, preventing, and managing all disease by the end of the century. A decade later, thanks to the converg...
What does it mean for a business to truly operate at the AI frontier? In a special crossover episode at Microsoft Build, Sarah Guo and Elad Gil team u...
We are now closer than ever before to living in a world where AI agents are smart enough to run our power grids and manage water supplies. How do we k...
Companies in Silicon Valley from Nvidia to AMD are racing to fuel the AI revolution with postage stamp-sized AI chips. Meanwhile, a chip the size of a...
Securing AI dominance requires more than just semiconductors; it demands a complete overhaul of how the West manages everything that goes into them, f...
The world’s first AI-take-private just proved that AI can revolutionize the real economy. Long Lake Management co-founder and CEO Alexander Taubman jo...
Baseten CEO and co-founder Tuhin Srivastava sits down with Sarah Guo and Elad Gil to discuss the rapid growth of AI inference demand, Baseten’s 30x gr...
More than fifty years ago, the modern idea of the standard enterprise software was birthed at SAP. Now, after managing companies through technological...
Few teens are business owners, but by age 16, Bill McDermott had purchased and was running a local deli. Now he runs leading global technology powerho...
AI agents can already collaborate, but they lack a trustworthy medium in which to store value and execute contracts. Enter Circle’s Arc Blockchain, an...
What happens when you apply the scaling laws of large language models to the physical work of atoms? Elad Gil sits down with Liam Fedus, co-founder at...
What happens when AI agents can design experiments, collect data, and improve — without a human in the loop? Andrej Karpathy joins Sarah Guo on the st...
Notion isn’t designing AI agents that just use tools. Their agents can autonomously build their own integrations, as well as write the code needed to...
By the end of 2026, AI capital expenditure is projected to hit nearly $700 billion. The question isn’t who has the best model, but who has the most cr...
In this episode of No Priors, Sarah and Elad dive into the evolving landscape of software, exploring how AI is transforming the traditional SaaS model...
Autonomous vehicle technology has moved past human-coded rules and into an era of neural networks and custom computer chips. And to solve the most dif...
From “virtual doppelgängers” to “real-time dreaming,” online gaming platform Roblox is using AI technology to build the “Holodeck” envisioned in scien...
What if we could pause biological time to wait for a cure for a disease? Thanks to innovations and research in reversible cryopreservation, this possi...
Why are there only a handful of companies in the world with over $10 billion in pure-play software revenue? CJ Desai believes the reason is that produ...
Today’s arms race looks a little different from those of the past. Under the Trump administration, the US Department of War (DoW) is deploying generat...
