Ologies with Alie Ward - Part 1: Attention-Deficit Neuropsychology (ADHD) with Russell Barkley

Episode Date: February 23, 2022

Focus. Productivity. Relationships. Distraction. Neurodiversity. How do you know if you have ADHD? How can you get others to understand your ADHD brain? What are your treatment options and how can the...y help? In Part 1, we talk racing thoughts, brilliant brains and the causes and effects of Attention-Deficit Hyperactivity Disorder with the world’s leading expert, Dr. Russell Barkley who is A BIG DEAL. Psychologist, retired professor of clinical psychiatry, author and speaker, Dr. Barkley has a personal connection to ADHD and has studied it for nearly 40 years. Is it all cute quirks? Nope. It’s serious business. But next week, we’ll hear about tips and tricks and self-love from 3 more experts — Jessica McCabe of How to ADHD, René Brooks of Black Girl Lost Keys and ADHD researcher Jahla Osborne. I’M TRYING NOT TO USE A BUNCH OF EXCLAMATION POINTS. It’s exciting. Dr. Russell Barkley’s website dedicated to education and research on ADHDDr. Barkley’s book, Taking Charge of Adult ADHDDonations were made to CHADD and Partners in HealthMore episode sources and linksSponsors of OlogiesTranscripts and bleeped episodesSmologies (short, classroom-safe) episodesBecome a patron of Ologies for as little as a buck a monthOlogiesMerch.com has hats, shirts, masks, totes!Follow @Ologies on Twitter and InstagramFollow @AlieWard on Twitter and InstagramSound editing by Jarrett Sleeper of MindJam MediaTranscripts by Emily White of The WordaryWebsite by Kelly R. DwyerTheme song by Nick Thorburn 

Transcript
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Starting point is 00:00:00 Hi, it's the Nat stuck to your lip gloss. Alli Ward, ADHD, it's here. It's here, take a minute, just breathe. It's exciting, here we go. Okay, who does one get for an ADHD episode? You ask me, your internet dad, when there are so many doctors and researchers and bloggers and TikTok coaches out there, who do you get?
Starting point is 00:00:23 You start at the top, the guy. You get the guy who has written more books than I can count. I literally was trying to count them and I had to stop and eat a granola bar. I was fatigued, but you may know him by the ADHD Bible taking charge of ADHD, which just released a new expanded, fresh as hell updated edition in November.
Starting point is 00:00:43 I have it, it's great. He also wrote 12 principles for raising a child with ADHD. When an adult you love has ADHD, professional advice for parents, partners and siblings. He is to ADHD when Oprah is to talk shows, the gold standard. So not only has he been a professor of psychiatry and neurology, a clinical professor of psychiatry and is cited in nearly every modern paper on ADHD,
Starting point is 00:01:05 but he also takes it to the streets. And by that I mean YouTube. His lecture videos are swiftly paced and have views in the millions. People in the comments are crying in relief. I was so nervous, we reached out, he obliged. We recorded my palm sweat. I decided this needs to be a two or maybe a three-parter.
Starting point is 00:01:26 So next week we'll talk to a few more experts, including Jessica McCabe of how to ADHD, Renee Brooks of Black Girl Lost Keys and Jayla Osborn, who's a researcher at University of Michigan. But we'll dive right in. But first quick thanks to everyone who supports this show at patreon.com slash oligies.
Starting point is 00:01:42 You can join for a dollar a month and submit your questions. Thanks to everyone who passes this episode along and who subscribes and who leaves reviews knowing that I read them all. Like Connor Cook, thank you for leaving the review. They say they were introduced to oligies via a keynote that I did at the Texas Science and Engineering Fair a few years back.
Starting point is 00:02:00 And their review made me cry. They said, they used my advice to show up like you belong. And they say that stuck with me as I struggle with social anxiety and doubt myself at every turn. And last week I interviewed for a position in a plant pathology lab. And I chanted that piece of advice in my head
Starting point is 00:02:15 and walked through that building like it was named after me. And I was just told that today I got the job. So congratulations on that Connor. That's great, full circle moment. And yes, I'm very proud of you. So okay, attention deficit, neuro psychology. Let's do it.
Starting point is 00:02:29 Heads up, this episode gets very real. We talk stats and neuroscience and personal experiences with ADHD. It also includes a mention about rates of suicide and a very brief nod to self-harm. Very brief. This episode doesn't sugar coat it. It doesn't condescend,
Starting point is 00:02:46 but it illuminates the hell out of ADHD. So next week we'll have more tips and hacks and self-acceptance for you too. Okay, so let's focus and let's learn about the brain chemicals that influence focus. What causes ADHD symptoms? How much diagnosis is enough diagnosis? The genetics component, risk factors, accommodations,
Starting point is 00:03:07 disorder versus disability. What screens have to do with it? Nutritional factors, tips for being in love and having a great relationship with an ADHD brain. How exercise comes into play. His personal connection with ADHD as well as mine with researcher, author, retired professor of clinical psychiatry
Starting point is 00:03:28 and internationally recognized authority on ADHD. Attention deficit neuropsychologist, Dr. Russell Barclay. Hello. Hi, Ali. It's Russ. How are you? Hi. How are you, Dr. Barclay? Please call me Russ. I'm doing fine. Thank you. Much better this month than last month. Oh, was that, was it a rough one?
Starting point is 00:04:05 Oh, God. I thought you knew. Oh, but I'm sorry I brought it up. I was in a severe car accident about eight weeks ago and I had nine broken ribs and it's been a week in the hospital. And so it's taken me a good eight weeks to recover, but I'm about 90% dead. And so I am thrilled to be alive.
Starting point is 00:04:24 I should not have survived, but I did. And I'm glad to be out of the hospital, didn't get pneumonia, all of which are lethal at my elderly age and doing well. So, yeah, I mean, it's just delightful to be able to talk to you. Oh my gosh. I had no idea. I'm so glad that you survived and are here. Yeah. Well, doing things like this gets me out of my head,
Starting point is 00:04:47 which is what you're doing. Because otherwise, you spend a lot of time in there and that's not good. I'm sure. And you are like a national treasure. I will have to say, like, hugely revered. You have, I'm so glad your life was spared because you have changed other people's so much. I'm so excited to talk to you
Starting point is 00:05:08 because I've had your book for years. I'm very well aware of taking charge of ADHD for a long time. I'm very well aware of taking charge of ADHD for adults, the guide for parents. I know you have a new version coming out soon also. Yeah, the adult book is out this month and the two parents books came out a year ago.
Starting point is 00:05:33 The 12 principles book and the taking charge of ADHD for parents were out last fall. And then I have one more coming out in end of the year, which is a clinicians guide. So that'll be, that'll be it. Four books during the pandemic. I'd say that's pretty good. How? How does one publish four books in a pandemic?
Starting point is 00:05:52 Well, it was writing and wine. That's what got me through the pandemic. And then doing drive by cocktails with my son and his family and get to see my grandchildren. And, you know, it was a heck of a year. So yeah, like everybody else, we may do. We adapt it. You know, one thing I've always been curious about
Starting point is 00:06:10 is your background because I've watched your YouTube videos. My husband has ADHD. I suspect I might, but you come up so often when ADHD experts are mentioned. And how did you come to be such a leader in this field? Well, I don't know if you're recording now or not. Yeah, yeah. Okay, very good.
Starting point is 00:06:32 Thank you. It's a long story, but I'll shorten it real quick. I had just gotten out of the Air Force. I've been back from Vietnam where I served with the Marine Corps actually, even though it was Air Force. And I finished and went to the University of North Carolina to complete my undergraduate work.
Starting point is 00:06:48 And while I was there, I was studying psychology and biology and trying to figure out how to blend the two. And I was looking for extra things to do to get into graduate school because getting good grades is not enough to go to graduate school. So I wandered around the medical center and volunteered 20 hours a week free of charge
Starting point is 00:07:07 if somebody wanted a research assistant. And everybody kept saying there's a psychologist upstairs that just got a grant, go talk to him. So I did, and he took me on as a research assistant within a month or two. I became his honor student and never looked back. And he was studying what then was called hyperactive child syndrome, but we now call ADHD
Starting point is 00:07:27 and doing studies on medication, imitation learning, very behavioral kind of operant stuff. And I fell in love with it. I love the kids. I liked what he was trying to do. He was a very paternal figure in my life at a time and I really needed guidance. And just great.
Starting point is 00:07:45 So it was Don Ruth was his name. He was also editor of one of our more famous journals. But Don kind of steered me correctly and I never looked back. I started studying ADHD, did my honors thesis, master's thesis, dissertation all within the ADHD space and then went on to specialize in child neuropsychology with a research focus on ADHD
Starting point is 00:08:10 because it's clearly it's brain-based problems. Although back then it was only a suspicion. Now of course it's been confirmed. So long story short, it was the influence of one guy in my life at a very formative time who sort of bent the twig, forced the pathway in that way. And I've always been grateful to him for it. Now it turns out, of course, ADHD is in my family
Starting point is 00:08:36 and it really helped me to understand my, I have a fraternal twin brother who died from his ADHD risk-taking. When he was in his 50s, a car crash. I lost his son, my nephew to suicide over very impulsive behavior following an argument with a girlfriend. I have other extended relatives who have the condition.
Starting point is 00:09:00 So it really, the personal side of it for me is it helped me understand my family members and particularly my brother who I grew up with who was just incredibly impulsive and risk-taking and all of those things quit school at 16, became a rock and roll musician, burned through three marriages, three kids he had no custody of, in and out of difficulties, gifted musician,
Starting point is 00:09:24 just Eric Clapton level talent. But that said, couldn't manage a dollar or his life at all and eventually cost him his life. But so it's personal for me. It's not just professional, they both intertwine but I didn't go into it for that reason but having gotten into it, boy did it help me to understand my family.
Starting point is 00:09:45 Yeah, I bet, I mean, it's hard not to get emotional just hearing that because I feel like a lot of what we hear about ADHD are the work and the productivity and the grades and so much of, I know personally my relationship with my husband before his diagnosis, most of our struggles were ADHD related that he had no idea, I had no idea. It really impacts people so much.
Starting point is 00:10:13 So is ADHD just cute and scatterbrained like an adorable manic pixie dream character in an early aughts romcom? Do you need bangs and cardigans if you have ADHD? Is it just a quirk acquired as an excuse for why you're late to brunch again? Well, it can be cute and I say that as someone whose partner has a lightning fast ADHD brain
Starting point is 00:10:32 that runs on curiosity, but it's also serious. In Dr. Barkley's 2018 Journal of Attention Disorders paper, Hyperactive Child Syndrome and Estimated Life Expectancy at Young Adult Followup, alongside co-author Dr. Mary Ellen Fisher, they write, the persistence of ADHD to adulthood was linked to an almost 13 year reduction in estimated life expectancy, 13 years.
Starting point is 00:11:01 There's a really gutting mountain of research on this, papers with titles like Attention Deficit Hyperactivity Disorder and Mortality Risk in Taiwan, which found that patients with ADHD had significantly elevated early mortality risk for suicide, homicide, and unintentional injuries compared with a non ADHD group. And there was a nationwide cohort study out of Denmark
Starting point is 00:11:25 that found the mortality rate ratios were more than double for those with ADHD. With higher risks for people who weren't diagnosed until they were adults. So it's even more dangerous if you're not diagnosed early. And the paper reported that the higher mortality was mainly driven from deaths from unnatural causes, mainly accidents.
Starting point is 00:11:44 And interestingly, along the study's defined gender binary, they found a higher mortality rate ratio in girls and women with ADHD and in males and will dive into gender and hormones and ADHD later in the episode, of course. So people who have been told to snap out of ADHD or that you just need to work harder or you don't have it because you're not a fifth grade boy doing a Fortnite dance on their desk.
Starting point is 00:12:09 To you, I hear your frustrated whales and I join you in that chorus of vindication and concern. I'm wondering when did we start to recognize it from just a behavioral problem in quotes of kids to what it is recognized as today? Yeah, well, I mean, we can go back nearly 250 years. People don't realize it, but I'm sitting here with an actual copy of the book dated 1770 in Germany
Starting point is 00:12:36 in which this is the first medical textbook ever written in German. It has a chapter called Disorders of Attention, if you can believe that. And in it, the author, Melchior Weikert, describes what today we would think of as classic adult ADHD. And back then they didn't know it caused it.
Starting point is 00:12:53 They had a number of recommendations for curing it, one of which was horseback riding, sour milk on top of some quinine. And if that didn't work, lock you in a room. Oh my gosh. So none of which works, but very interesting, stuff nonetheless. But follow that forward.
Starting point is 00:13:09 Okay, nothing's written about 15 years later, his student Alexander Creighton writes a textbook. He also has a Disorder of Attention chapter, which he describes two attention disorders, one of which is ADHD. And then things kind of get buried for a while until the late 1800s. Fast forward up to 1900, George Still publishes
Starting point is 00:13:29 three papers of his lectures, in which he describes these children. Then we have the 1918 flu epidemic, in which we have a lot of kids developing ADHD who survived the flu. But we didn't really get into the, what I consider the modern age of science until the 1970s.
Starting point is 00:13:47 And I just happened to be coming into the field at the moment where the match was lit. I mean, the fuse was lit and things began to take off. We started seeing research papers, objective evaluation of these children using all kinds of measures, longitudinal studies were started. So yes, first described perhaps in the late 1790s
Starting point is 00:14:08 by Weichert in a chapter titled, Sickness of the Spirit as a Disorder of Attention, but treatment took a turn for the more informed in the 1960s and 70s. That to me is the modern age of research. And then by 1990, we had all the neuroimaging stuff was beginning to start by the year 2000, molecular genetics was kicking off
Starting point is 00:14:30 and everything just exploded after that. So we go from a couple hundred papers in 1960 to 400,000 as of a few years ago. I mean, it's just startling to go to Google Scholar, enter ADHD in its precursor terms and do the math. I mean, it's just enormous. I know I read all research every week on Fridays published in the world
Starting point is 00:14:56 and it's 35 to 40 articles a week. So do the math on that. It's 1500 to 2000 papers a year are now coming out on this disorder. So this is no myth. It's very, very well researched. It's got a tremendous amount of evidence for its validity and neurobiology
Starting point is 00:15:16 and genetics and life course and risks. So it's an incredibly well understood disorder, but we didn't really get into it, I would say until the late 1960s, early 1970s when people started to take it seriously. You mentioned something about the flu pandemic and survivors of, was there some reason why there was a correlation made there?
Starting point is 00:15:39 Well, yeah, we had children who if they survived, this was the Vonokonimos encephalitis that swept through following the First World War and it took over Europe and then spread here. It left people with a lot of secondary injuries to their brain if they survived because the virus attacked the brain and it left children with altered personalities,
Starting point is 00:16:03 altered abilities, reduced mental capacity. But one of the hallmark symptoms was hyperactive behavior, incorrigibility, lack of self-control. So you had children's personalities literally changing overnight, which the disorder actually back then was called postencephalitic behavior disorder.
Starting point is 00:16:23 Then they eventually realized you could get it from other brain injuries and it became brain injured child syndrome. And then people said, well, wait, there are other children with these behavioral problems, but we don't have evidence of brain injury. They then called it minimal brain damage. And then it became minimal brain dysfunction, MBD.
Starting point is 00:16:39 And only in the 1960s did people say, wait, wait, wait, stop talking about causation because we really can't peer into the brain to see if there's damage there for most of these kids. Let's just focus on their behavior. And that's when it became hyperactive child syndrome. So it was really in the 60s when the shift came moved away from etiology,
Starting point is 00:17:02 like it's gotta be a brain injury, which we still thought but couldn't prove to let's just focus on behavior. So hyperactive, inattentive, impulsive behavior became the holy trinity of ADHD and we stopped speculating about etiology for a while because we didn't really have a lot of hard evidence other than by inference.
Starting point is 00:17:22 Brain injuries caused this syndrome. Therefore, people who show the syndrome, ergo must have a brain injury of some kind. But it was just that kind of logic. But it took neuroimaging to come around in the 1990s, followed by molecular genetics and all the studies on inheritance. And now we link the two.
Starting point is 00:17:43 We study the effects of genes on brain networks now. And it's all just really come full circle. But that's when the behavior became the focus rather than the brain injury. Now, of course, we blend them all together. And first off, I'm so sorry about the way it's affected your family and having lost your brother.
Starting point is 00:18:04 Oh, well, thank you. You mentioned he was a fraternal twin. Yes. Can you talk at all about what causes it from a neurobiology from a genetic level? What we found? Yeah. Yeah, I'll try to oversimplify
Starting point is 00:18:21 because let me tell you, it is so complicated that I have trouble keeping up with it. I mean, you really have to specialize in each of these areas, whether it's brain microstructure or white matter or neuroimaging or functional connectivity. They're becoming almost specialties in themselves. Let me give you the grand picture from 30,000 feet. Just a fun side note, I was editing this part
Starting point is 00:18:44 at 30,000 feet in a plane. I was like, oh, weird. Anyway, causes of ADHD. Let's get into it. You really have two essential domains of causation here. One is genetics and the other is neurological injury producing maldevelopment. And so I'll just very quickly,
Starting point is 00:19:05 I'm gonna oversimplify, about two thirds to three quarters of all ADHD cases fall on the realm of genetics. They're either inherited or they come about through what we call new or de novo mutations. I'll come back and explain that in a moment because that's fascinating. But the second is that about 25 to 35% of the cases,
Starting point is 00:19:25 particularly in boys more than girls, are acquired. And most of the acquired injuries are occurring during pregnancy. So if we break down that 25 to 35%, at least two thirds to three quarters of them have had this problem due to something happening during pregnancy to the developing brain and the executive networks of the brain
Starting point is 00:19:46 that leave the individual with this disorder. Now, what could that be? Multiple infections that the mother has. Premature delivery that leads to being in a neonatal intensive care unit leads to brain hemorrhaging in these brain areas. We also have maternal obesity and type two diabetes that the mother may have.
Starting point is 00:20:05 That's kind of questionable, but that's there. Maternal consumption of alcohol, very well proven. If you're consuming alcohol at high rates, you're poisoning your child's frontal lobe. And we could go on it. We thought smoking might be in there, but it turned out that smoking was just an index that the mother had adult ADHD.
Starting point is 00:20:23 And when you controlled for the mother's ADHD, smoking went away. So that was kind of a marker, not a cause. You've got all of these, just about anything that can happen during a pregnancy that might impact that brain, and particularly the frontal area, which is one of the most sensitive areas to injury in humans, because it's so new
Starting point is 00:20:44 and evolution can cause that. So you've got all these acquired cases, about 10% of whom acquire it after birth, through what? Head trauma, lead poisoning, other exposure to toxins, heavy exposure to pesticides, probably. But the biggest ones are the toxins, such as lead, but especially closed head trauma.
Starting point is 00:21:08 And that can lead to this as well. So you've got the acquired cases, and then you've got the other two thirds to three quarters that came by it, honestly, so to speak, genetics. Most of those people inherit this behavior pattern in their families. It's there, as it was in my family, and it gets passed along.
Starting point is 00:21:27 However, we have now learned that about 10% of all cases of ADHD are due to new mutations occurring in the parent's sperm and eggs that are not present in the parent's blood. So if I did a blood sample, I would not see these mutations. But if I sample your sperm, or if I look at your child, I will find the mutations in that baby, and you and your spouse don't have them,
Starting point is 00:21:55 unless I look at eggs and sperm. Now, how is that happening? Because the longer you wait to have children, the more your gametes, as they're called, your eggs and sperm, are likely to suffer mutations from just surviving, from radiation, from chemicals, from external trauma, to male testes, and things like that, you are racking up mutations.
Starting point is 00:22:17 And if you wait a decade to have children from age 20 to age 30, then you now have eight times more mutations in your eggs and sperm, but particularly in your sperm, males are more likely to have this, and those get passed along to your child. Now, you say, well, so what? Well, it turns out that the genes most likely to mutate
Starting point is 00:22:38 under these circumstances are the genes for self-regulation, language, and sociability. So guess what goes up? Autism and ADHD. The longer men and women wait to have children, those disorders begin to rise in frequency. So some of the rise we've seen in both of those conditions over the last 20 years has been the shift
Starting point is 00:23:00 in delayed parenthood as a result of people wanting to have it all, have the job, have the career, have the house, and then we'll have our kids in our 30s. Just a side note, this isn't just a factor of wanting it all either, of course. This has been heavily influenced by the 1965 Supreme Court victory of Griswold versus Connecticut,
Starting point is 00:23:20 and that eliminated local and state laws that barred access to contraceptive pills. Plus, there was the 1973 Roe v. Wade case, and this sociologist, Dr. Constance Sheehan, writes a lot on this, and also explained in paper that the Civil Rights Act of 1968 included Title IX, which was the Fair Housing Act, and that prohibited discrimination selling homes
Starting point is 00:23:44 to people of any race, color, religion, national origin. In 1974, they were like, oh, I guess we should add gender too, huh? And then this acquisition of equal rights was then blamed for housing prices going up and everyone having to be dual income in order to purchase a home, making it nearly impossible to afford a place to live
Starting point is 00:24:04 and to afford children until you're like 50, but that is a whole separate episode. Anyway. So, you know, I understand that's complicated. I could really get into the weeds, believe me, this really is the 30,000 overview, but that's what's going on here. So notice, multiple causes all converging
Starting point is 00:24:24 on a single network in the brain that is the brain's executive system that gives us self-regulation, and for various reasons, it goes wrong. Can you go through perhaps a few of the most noteworthy impairments or symptoms? Because I know probably a lot of us feel like, oh, my focus is fractured,
Starting point is 00:24:45 or I can't put down my phone. It's difficult to parse out. Well, you know, I'm glad you asked that, because there's a lot more going on here than the surface features of inattention, distractibility, impulsiveness, and maybe some hyperactivity, though that's really an early childhood symptom
Starting point is 00:25:03 more than it is an adult symptom. But that said, to me, that's the superficial nature of ADHD that everybody sees. Now, let's look under the hood. What's going wrong under the hood in the mind that is leading to you to behave that way? And that's where we get into the executive functions. And there are seven major executive functions
Starting point is 00:25:25 that come from largely your frontal lobe, but also interactions elsewhere in the brain, and they give us our capacity for self-regulation. They take about 30 years to mature, and they're delayed in people with ADHD by several years, or what I estimate to be probably around 25, 30%. But, you know, the number doesn't matter. The fact is, these abilities
Starting point is 00:25:44 that everybody else is getting, you're not getting. What are they? Let's have it. Number one, inhibition, self-restraint. Number two, self-awareness, the ability to monitor and attend to your own behavior. Both of these start very early in life. Each takes at least 10 years to mature, if not more.
Starting point is 00:26:03 And then when those start to kick off, you get the next two, which has to do with working memory. And the first one is nonverbal working memory, but you know it as visual imagery, which is a capacity to imagine things. You recall images in your mind from your past, call it hindsight, and you use those to anticipate what could happen next, foresight.
Starting point is 00:26:25 The fourth thing you're gonna get is the mind's voice. You're gonna start to develop language to yourself. It's all out loud. Little children talk out loud to themselves. But by the time you're eight to 10, that should be in your head. You should be able to talk to yourself without people hearing you,
Starting point is 00:26:39 and without you moving your lips in your face. And so now you've got four executive abilities. You can self-restrain, you can monitor yourself, you can visualize to yourself, and you can talk to yourself. And that's a little Swiss Army knife of mind tools that allows you to control yourself. Then you get the next three. You use those four to manage your emotions.
Starting point is 00:27:02 So emotional self-regulation comes next. And with that, right along with it, is self-motivation. And then finally, you get the biggie, the last one, which is planning and problem solving. The ability to manipulate stuff in your head to come up with solutions to get around obstacles and help you get to your goals and solve your problems. And Dr. Barkley cites the work of Dr. Joel Nigg,
Starting point is 00:27:26 who argues that ADHD is more of a spectrum disorder with wide ranges in impairment. And an incredibly oversimplified 60,000-foot view is that the brain has two kinds of signaling. Bottom-up, where what we sense influences our attention and our emotion, we react to it. And then top-down, where we respond to that bottom-up signaling and toss a command back
Starting point is 00:27:52 from our prefrontal cortex to the interior and the back of the brain to say, hey, it's cool, we're good, we're good. Don't worry about it. So in an article in Attitude Magazine, Dr. Nigg writes that in a neurotypical brain, there's a good balance of top-down and bottom-up signals. But in the ADHD brain, the top-down signals
Starting point is 00:28:11 are relatively weak and possibly overpowered by the screaming bottom-up signals that are reacting to stimuli. So what is the result? Things like inattention, impulsivity, and emotional dysregulation, leading to a spectrum of those seven deficits. You know, the ones we mentioned a couple of minutes ago,
Starting point is 00:28:30 so pop quiz, what were they? Come on. Were you not listening? Can you not name the seven? Okay, just kidding, probably no one can. What were they? They were self-awareness, inhibition, nonverbal working memory, aka mental imagery,
Starting point is 00:28:46 verbal working memory or your inner monologue, emotional self-regulation, self-motivation, and then planning and problem solving was number seven. There will be no pop quizzes in this episode. That would be mean and not fun. Those are the seven deficits that people with ADHD have to varying degrees. How would you recognize that?
Starting point is 00:29:06 You would see that because, number one, they're very impulsive and show very poor self-control and self-regulation. Two, they're not as aware of their difficulties as are the people around them because they're not self-monitoring to the extent that you do. Three, they are horrible at time management
Starting point is 00:29:24 because the working memory system in part gives you your sense of time and timing and allows you to think about the future to deliberate what is coming next and then to use that to inform your own behavior. So time management, it becomes a major deficit that just gets worse and worse with age because life becomes more time sensitive with age.
Starting point is 00:29:45 Three-year-olds don't have to manage time. 30-year-olds are incredibly time sensitive. Most of your day is filled with deadlines, schedules, promises, commitments, bills, everything has a time tag on it. And so that's when I came up with the word, as you saw in my book, time blind. Adults with ADHD, kids are too, but especially adults,
Starting point is 00:30:06 struggle with this concept of time and how you cope with this and manage yourself relative to it. And then, of course, you're gonna see the emotional self-regulation problems and positive emotion, difficulties getting control over your emotions, whether people can do,
Starting point is 00:30:22 you're gonna have a lot of trouble with self-motivation, you're gonna procrastinate. Anything that doesn't have an immediate payoff is very hard for you to stay with and you'll keep being distracted by anything that offers you a promise of immediate gratification. And then when you're faced with problems, instead of sticking it out
Starting point is 00:30:39 and trying to problem solve people with ADHD tend to quit, they tend to simply shift over and go do something else. And so they have a life that's, you know, filled with half-completed projects and goals they could never reach and accomplishments everybody else is able to do and they can't do or they struggle to do. And so it really gets very demoralizing
Starting point is 00:30:59 by the time you're a teenager or an adult because all these problems are piling on year after year as other people get each of those executive abilities, you get another deficit. So by adulthood, you have at least seven or more problems with self-regulation that other people don't have. And it leads to a whole swath of downstream problems
Starting point is 00:31:25 in major life activities that people just don't realize. ADHD is one of the most impairing disorders we treat in an adult outpatient basis. And people think it's just some trivial little problem that a cup of Starbucks is gonna solve. Have you seen the way clinicians classify it? And I understand it's a deficit, it's a disorder.
Starting point is 00:31:46 Is it looked at as a disability more so accommodations can be made or how is that language changing? Well, the clinicians call it a disorder because that's our term for anything that creates excessive, persistent, and severe symptoms that lead to harm to the individual. So there are two criteria.
Starting point is 00:32:08 First, you have to have serious and persistent symptoms that go well beyond your age and your sex, your gender. So second is it must be producing impairment, harm. You must be suffering. The environment must be kicking back. So that you're experiencing hardships. And when those two criteria are met, you have a disorder. So that's the clinical term.
Starting point is 00:32:32 Now, the government, however, invented the concept of disability. So the government comes in and says, how disordered are you? Are you disordered enough that we would consider you to be disabled in various major life activities like school or work or self-support or by self-support.
Starting point is 00:32:53 I mean that you can dress yourself and bathe yourself and support yourself and so on. So the term disability is really a government term for whether or not your disorder rises to the level that you deserve accommodation support, social security, disability, ADA accommodations, IDEA school accommodations and all these other things. So that's really the difference.
Starting point is 00:33:16 Clinicians use disorder, governments use disabilities and the two of them blend together. Just a quick follow-up on that. I asked the Allinges Twitter how neuro atypical people self-identify. And I found the sentiments essentially echoed. At Anna underscore George said that, quote, my experience is that disability trumps disorder
Starting point is 00:33:37 in terms of academic accommodations and that it seems like you need to have a, quote, disability in order to seek accommodations as well. And I have a friend, David Radcliffe, a TV writer who is the chair of the Disabled Writers Committee at the WGA West, which is a big deal. And he chimed in and said, yes, this is part of the push to de-stigmatize the word disabled
Starting point is 00:33:55 because recognizing someone is disabled, not special needs or differently abled, offers them legal protections, et cetera, under the Americans with Disabilities Act. And I thought this was interesting. Allingite, Quinn's quirks noted that they think it depends on the person and what that community thinks. And some communities prefer the term condition
Starting point is 00:34:14 in place of disorder, they say. The autistic community, they write, has been talking about reframing autism spectrum disorder to autism spectrum condition. But in general, accommodations and support are a good, equitable thing. Please, more of them. And when you are neurodivergent,
Starting point is 00:34:30 framing your own experience in a way that is comfortable to you is important. And Jared refers to his ADHD as his good, bad brain and we're constantly celebrating his brain for what it is and what it does, while also acknowledging that having ADHD is not always a fucking picnic. And now let's talk about, as my husband calls it,
Starting point is 00:34:50 his friend Dopey, dopamine is constantly wrangling with Dopey. What is the role of dopamine in ADHD? Well, we used to think it explained everything and now we know that things are a lot more complicated. But back in the day when I came in in the 70s and 80s, the guessing was that ADHD had to be due to dopamine deficiency because the drugs we've discovered to manage it all produced increases
Starting point is 00:35:20 in dopamine availability in the brain. And they did it through various mechanisms. They don't all do it the same. But at the end of the day, the net result is that there's more dopamine in the brain to do the job that it's not doing in people with ADHD. And it turned out that while that is true, we also began to discover that norepinephrine,
Starting point is 00:35:40 which is related to dopamine, also is implicated in the disorder. Hence, you have Eli Lilly coming out with Strattira, which is an norepinephrine drug that increases norepinephrine in the brain. Then you have the new Calvary that came out just this past April. And that's a new drug.
Starting point is 00:35:59 That's a norepinephrine drug. But then we also began to realize now, wait a second, there's other things going on in the brain here. We're discovering that these alpha two ports, as they're called in the frontal lobe, which are little, I'll call them sphincters. Sphincter says what? But portholes on neurons in the frontal lobe
Starting point is 00:36:19 that open and close to determine how much noise is in the nerve cell, that these alpha two ports, which are responsive to alpha two drugs, also are beneficial for ADHD because they fine tune the nerve signals in the executive brain. So we can get at ADHD now through at least three
Starting point is 00:36:40 and probably more neurotransmitters, dopamine being one, and that's what the stimulants are doing. Norepinephrine being the other, and that's what the non stimulants are doing. And then managing the alpha two ports and the noise in the frontal lobe. And that's what the antihypertensive drugs are doing, clonidine and guanfacine.
Starting point is 00:36:58 So we've got six different medications out there. And we've got many, many new delivery systems for those medications. But those are the three classes of medicines that we're using. So you can see that there's more than just dopamine. And now we realize that it goes beyond neurochemistry because the genes we're discovering for ADHD,
Starting point is 00:37:19 of which we've already found 12, we're guessing there's at least 45 to 50. There's actually a recent paper from last week that shows that it's probably closer to 500. But there are multiple genetic sites in the human genome that build and operate your brain. And ADHD results from having different pairs of these genes than other people have.
Starting point is 00:37:41 So you and I both might have the dopamine gene DAT1, but your version is different than my version. You might have seven, eight or nine copies of the DAT1 gene, whereas the average person has four or five. And those extra versions are wreaking havoc in building the brain. They're creating a very different brain than other people get.
Starting point is 00:38:07 And we see this very early in the development of the brain where nerve cells that are under the control of these genes are not migrating properly. They're not growing properly. They're not reaching the endpoints in the brain where they should be connecting properly. And it leads to problems with connectivity in different brain centers.
Starting point is 00:38:25 There was literally a paper yesterday published on 32,000 people with ADHD demonstrating, beyond a shadow of a doubt, these functional connection difficulties in children developing ADHD. So it was just staggering to see the number of different regions that are not connecting as well as they should.
Starting point is 00:38:48 And even when they connect, the connections are quite variable in how well they function, creating a lot of variability and behavior. So, just to say that we're linking behavior with brain, brain with genes, genes with functional connectedness in the brain, and you just have to sit back and go, wow, I had no idea at the level of complexity.
Starting point is 00:39:10 So it's beyond dopey. Yes, I will definitely tell him. And when it comes to creating the architecture of a treatment plan, whether it's medication or rather deciding medication, how does someone go about figuring out which of those three types of medication from stimulant to non-stimulant
Starting point is 00:39:31 to maybe even hypertension drugs? Do you recommend trial and error? So at this point, besides clinical trial and error, as well as clinician preference, let's understand some clinicians prefer, they're more comfortable with working with certain drugs and other drugs. We know in research that we can create literally
Starting point is 00:39:51 a checklist of different issues that one might want to contemplate in choosing a medication. One would be urgency. How fast do I got to get control over your problem because you are experiencing a lot of suffering? Well, the stimulants would be the choice because they work much, much faster
Starting point is 00:40:10 than the non-stimulants do. Okay, but on the other hand, you have an anxiety disorder. Well, yes, I think I do. Well, hold on a second. We know that in a subset of people, stimulants can make anxiety worse. That's arguable. It doesn't happen in everybody,
Starting point is 00:40:26 but it happens enough that clinicians get a little concerned about that. And that's where we might want to go with a non-stimulant, like a Strattira or a Calvary because that actually treats anxiety in the context of ADHD as well. Well, then we might also have somebody who's showing very high levels of hyperactive aggressive
Starting point is 00:40:44 and just sort of over aroused behavior. Well, I might prefer to use an antihypertensive drug or would recommend to my colleague because I don't prescribe being a psychologist, but that's where we would look and say, well, that drug actually does very well at managing hyperactive impulsive aggressive behavior. Maybe we'll go there.
Starting point is 00:41:05 I could go through all 15, I won't, but sophisticated clinicians will think that through and say, you know, given your portrait of your disorder as well as your other disorders, let's remember that 80% of people with ADHD or more have a second disorder. 50% have two more disorders. So we're really dealing with disorder combinations here
Starting point is 00:41:28 and very rarely are we dealing with ADHD alone. It's about one out of every seven cases is a pure ADHD case. So to me, the real clinical work here is in how many disorders do you have? How do they affect my treatment planning? What drug should I be using given your constellation of issues and urgency? Are you a college student living away from home?
Starting point is 00:41:52 Well, one in four of those kids diverts the medication. Maybe I'm not gonna send Adderall or Vivance into that environment just yet until we see how responsible you are with a schedule two stimulant. You know, it's just thinking it through and knowing where your prescription's going and who's using it and who's around you
Starting point is 00:42:11 and how responsible you can be, et cetera, et cetera. So there's a lot of complexity to walk through, but many clinicians simply go trial and error. I'll start with this one. That doesn't work. I'll go to the next one, then the next one. And eventually about 93% of the time we find a drug that works for you, but not always.
Starting point is 00:42:29 Fingers crossed. What are some of the reactions you've heard from people who have been either recently diagnosed or recently medicated in terms of how that changes the way that they live their life? Oh my God. I mean, let's understand about eight to 10%, we don't, the drugs don't help them at all
Starting point is 00:42:46 or they have adverse reactions that we have to stop. But for the remaining 90%, what we find is that, now get this, 55% are completely normalized on the medication. Wow. Normalized. I mean, they're no different from anybody else. And those are the people who say, you saved my life.
Starting point is 00:43:04 Oh my gosh. I can finish my college. I saved my marriage. I can manage my children. I literally can have an intelligent conversation without going all over the map and mind wandering and not being able to even remember what we were talking about.
Starting point is 00:43:20 By the way, just as an aside, if you have not Googled Danny Donovan, Google her, she's an illustrator who's created some hysterical cartoons and illustrations about what it's like to have adult ADHD. Danny Donovan's website is ADHDDD.com and that'll be linked on my site. And for more great ADHD comics, also see ADHD underscore alien on Twitter
Starting point is 00:43:43 and that's by Pina Vernell. And so, you know, have a look at Danny and you can also go over to the website, how to ADHD. Jessica's got a great website over there as well. And stay tuned for Jessica McCabe of How to ADHD in a special part two next week, along with Renee Brooks of Black Girl Lost Keys,
Starting point is 00:44:02 who also runs an online support group for black people of marginalized genders and that's called the Unicorn Squad. So we'll be chatting with both of them and also Jaila Osborne of Black and Neuro, who is an ADHD researcher. So I'm telling you, this is why this episode took so long. It was too exciting.
Starting point is 00:44:17 I kept adding more and more things. So these are just resources that get it. And when you see them, you say, oh my God, that is me in spades. You know, like Danny has an illustration where she said it's either now or not now and she's got a light switch. That's it, you know, that's her concept of time
Starting point is 00:44:36 is now or not now. And if it's not now, I don't care. And if it's now, I'm all over it. So I can hyper focus on it. So she has a diagram of what it's like to have a conversation with her. And the diagram for the typical person is I started A and I want to explain this and I get to B
Starting point is 00:44:55 and it's a straight line. Hers looks like a maze of all over the place, getting distracted, talking about irrelevant things, can't remember what we were describing, have to ask you what we were talking about, you know? And so she's just everywhere. And that is so typical of ADHD. So all of that is to say that people who get diagnosed,
Starting point is 00:45:18 first of all, the diagnosis alone is therapeutic because it takes you out of the realm of moral judgment and puts it in the realm of neuroscience. You know, up until then you thought you were a bad person. You were at lay about near do well. You were lazy, unmotivated. Your mother was right, you know, you just failed to launch. You know, we just can't get you out of here.
Starting point is 00:45:40 And you know, and you buy that, you become so demoralized about yourself because everybody else is succeeding and here you are stuck, you know, in quicksand and you can't seem to get from A to B. And so you start blaming yourself and you literally buy into the societal stigma that there's something wrong with you
Starting point is 00:46:02 in terms of your personality and your morality and your self-discipline. You just have no willpower. When you get the diagnosis, it's now in the realm of neuroscience and you get it. You are experiencing a neurodevelopmental disorder or disability and that alone to me, that mindset becomes very therapeutic
Starting point is 00:46:21 because you didn't cause this. You're not choosing to be this way. You can't get up and smell the coffee tomorrow and become a different person. You are struggling as our people with autism spectrum or bipolar disorder with something you didn't ask for but that you've been blessed because of your genes or other factors
Starting point is 00:46:39 that you now have to cope with. So on the one hand, I'm taking you off the hook. You didn't cause this and neither did your parents in terms of how they raised you. On the other hand, I'm gonna put you back on the hook because you're the person that has to do something about this. And there's nothing wrong with that.
Starting point is 00:46:55 That's the neurodiversity movement in spades. You're just a neurodiverse person but you gotta stop denying and blaming and shifting the source of the problem to your spouse or partner or boss or mother or friend because you're the common denominator here. I took my twin brother 37 years to wake up and realize that his life was the result
Starting point is 00:47:19 of his decision making and not all the other people he wanted to blame for that. And I see that all the time. So I really love that idea about, you gotta own it before I can help you. So Dr. Berkeley notes that maroon five singer, Adam Levine, I think he's also on the show where you push the button with the chair.
Starting point is 00:47:38 He is a person with ADHD and he participated in this pharma campaign a few years back called Own Your ADHD to destigmatize neurodivergence but also empower people with adult ADHD to be active stewards of their treatment. And given that approximately 10 million adults in the United States are estimated to have ADHD,
Starting point is 00:47:59 that's an important thing. But who's not feeling overwhelmed and distracted and forgetful sometimes and maybe a little emotional, particularly these days. So how do you know if you actually have ADHD? What if you relate to every TikTok but you feel like everyone relates to every TikTok? Can I just pee on something
Starting point is 00:48:16 and wait for a line to materialize yes or no like the ghost of executive function past? And you mentioned that process toward diagnosis. I've heard it from everything as if I give you Ritalin and it works, you have ADHD. If it doesn't work, you don't have ADHD. I've heard that. That's not true.
Starting point is 00:48:35 Not true. And to my cousin who in her 30s finally realized that she had ADHD through a long diagnostic process that involved interviewing her loved ones to ask about her background. And it was a huge relief. So when it comes to diagnosis, I feel like that in itself,
Starting point is 00:48:50 I think if you have ADHD, there's a lot that can already about life be really intimidating and overwhelming. Yes, yeah, there can. I know that my husband just the struggle to get his Adderall refilled every month involves going to six pharmacies and getting paperwork mailed and he's like, this is the one thing I'm already bad at.
Starting point is 00:49:10 Yeah, I know. And it's a schedule two drug, unfortunately. The other drugs are not, but the stimulants are scheduled to, which means they have the potential to be abused. And that's why they clamp down on them and all the paperwork. And then you're gonna run into the occasional pharmacist
Starting point is 00:49:24 who believes in Tom Cruise in Scientology and may lecture you about the evils and the wickedness of the prescription you're trying to fill. Let me tell you, I've had families call us and saying, you're not gonna believe it. This pharmacist is telling people. Oh my God.
Starting point is 00:49:38 You know, and it's like, well, then switch pharmacies. You know, we're not gonna deal with, you know, Tom and his disciples here. No, that's right. So, you know, there are other people who think this is just a myth and you're using this as a crutch and it really doesn't exist.
Starting point is 00:49:50 And all of which is so naive, it goes without saying. I mean, every time I hear somebody say, you know, this is a myth or it's just so trivial, it reflects to me a stunning ignorance of the real science of the hundreds of thousands of research papers. And it really tells me more about you than about the disorder. So that said, so can I walk through
Starting point is 00:50:13 just what I think are the five things you really gotta do to deal with this disorder? And I'll make them very quick because I know we have other things to chat about. But number one is get a proper diagnosis and identify the various disorders that may be there because there's often more than one and we have to treat them all.
Starting point is 00:50:33 So I call it, you know, evaluation, that's step one. Oh, okay, great. Step two, education. Read, read widely. David Lindsay, the novelist, had a great phrase in one of his novels, truth is an assembled thing. You don't get it from one guru, one website, one book.
Starting point is 00:50:51 I want you to read widely, but read credible sources, the foundations, the charities, the NIH, the chat organization, and Canada, the cadre organization, theadd.org here, the World Federation for ADHD. There are at least 10 websites with lots of information, including my website, which has a lot of free fact sheets on it.
Starting point is 00:51:13 Just read widely, read the books, go to YouTube, look at my videos, acquire the information because you're going to assemble, you know, out of that, the truth keeps popping its head up and the nonsense will fall by the wayside because it won't be replicated across these websites. And you'll begin to get a really core understanding of yourself and your disorder.
Starting point is 00:51:35 Number three, medication. Of all the treatment components, that's the most effective we have. And it doesn't matter whether you like that, whether you agree with it, medication's not a religion that you believe in, the facts are the facts. It's three times better than anything else out there.
Starting point is 00:51:52 And while it doesn't help everybody, it helps most people to an incredible degree and as I've said, it can actually normalize over half of the people who take it once we find the right medicine. Just to note on the word normalization, that's a clinical term that means the use of medication to bring mental functioning or performance
Starting point is 00:52:12 in line with a prevailing cultural norm as opposed to trying to achieve performance enhancement. So the norm is the typical. Normalization could be easily called typicalization. So medication. And I look at ADHD as the diabetes of psychiatry. You would never turn away insulin if I told you you were a diabetic.
Starting point is 00:52:33 And yet you have as much a biological problem as the diabetic has. Why are you turning this down? It's because you think the medicines are covering something up, that they're a bandaid and they're not. The medicines are exactly like insulin. They literally are correcting the neurogenetic basis
Starting point is 00:52:50 in the brain that is giving rise to your symptoms. So part of owning it is realizing if this is neurobiological, there is nothing wrong with a biological agent being part of the treatment package. It's not the sole thing we do, but it's an effective component, one of the most. I'll link all that and the other sources he mentioned on my website at alleyword.com slash ologies slash ADHD,
Starting point is 00:53:15 which is linked in the show notes. Also, once a pharmacist told me that I didn't need the antidepressant. I was prescribed to deal with mood swings from my ovarian failure. I just needed Jesus. And this was a pharmacist in LA, so Russell's not kidding. Anyway.
Starting point is 00:53:32 Okay, so we've got evaluation, education, medication, next, modification. What can I do to modify my behavior in order to cope better with the demands of this disorder? That's where cognitive behavior therapy for executive function deficits come in. That's where adult ADHD coaching comes in. That's where learning mindfulness meditative approaches
Starting point is 00:53:55 like in John Mitchell and Lydia Zilaska's new book that just came out on mindfulness-based practices for adult ADHD. These are the things we want you to participate in. And if you're on medication, you're more likely to benefit from them than if you're off your medication because they're just what the medication does
Starting point is 00:54:13 to help you with organizing yourself and persisting and motivating yourself. So number four is modification to the extent that you can. Remembering it's neurobiological, but there's some latitude there that some give and take and how you deal with yourself. Number five, accommodations. Accommodation refers to how can I physically change
Starting point is 00:54:33 my environment so that while my disorder is still there, I'm not impaired by it. And that means looking at your workspace, looking at your computer and saying, okay, all games go on the computer over in my den and only the computer in my office has work apps on it. Even then, I'm gonna download apps that deal with time management and self-regulation
Starting point is 00:54:56 that block out distracting websites, but no gaming on this computer. That's an accommodation. It's like a ramp coming into a building for somebody physically disabled. You didn't get rid of the physical disability, but you allowed them to participate effectively in the things that the rest of us can do.
Starting point is 00:55:11 So things like time management and using a day planner and a week at a glance calendar and outlook and making yourself accountable to your colleague, your boss, your supervisor, your spouse for the things that you commit and checking in with your adult ADHD coach several times a week on your goals and your strategies and what you were trying to do.
Starting point is 00:55:32 These are all ways of rearranging your environment so that you get to do the things your disorder otherwise would preclude you from doing, but you're still ADHD. You still have to own it, but oh my God, there's hundreds of things in my book that we talk about of ways of altering environments to lessen the impact of the disorder.
Starting point is 00:55:52 A few tips, Bluetooth noise canceling headphones, maybe prayers to the universe that your employer doesn't think a bunch of open tables all in one giant room fosters corporate community because it doesn't study show that people get about a third of the work done and have higher rates of anxiety, illness, and turnover in a bullpen type of office environment.
Starting point is 00:56:15 So cubicles with opaque walls or an office with a door, if possible, getting those things from an employer might require advocacy on your own behalf, but it can be worth it. But you won't do those if you don't own that disorder. So again, to reiterate, evaluation, education, medication, modification, accommodation. Do all five of those and you will be doing a great job.
Starting point is 00:56:41 What about that evaluation? Any tips on how in depth that evaluation needs to be? I don't think the diagnosis can be accurately or reliably made in less than two to three hours. Now, that may mean that I'm gonna see you three times for 45 minutes to an hour because of the way physicians and psychiatrists schedule their time.
Starting point is 00:57:03 Psychologists, on the other hand, are used to blocking out three to five hours to do their evaluations all at once. So just to understand it, it may not be done all at once, but it usually takes that long because I've gotta go back through your history. I've gotta survey all of these symptoms. I have to look across all these disorders.
Starting point is 00:57:21 I have to have you complete these rating scales and score them up and then I have to interpret those. I may need to do some psychological testing with regard to your intelligence and your achievement because two of the rule outs for having problems in work and education are, do you have adequate intelligence for the environment that you're in
Starting point is 00:57:41 and do you have any learning disabilities? Because 50% of people with ADHD also have a learning disability that's not their ADHD. And if I don't realize that, then I've missed part of the explanation for why you're struggling in school or college or in the workplace. There are other tests like the QB test or TOVA,
Starting point is 00:58:02 which may track an infrared ball attached to your forehead as you undergo some computer quizzes, but Dr. Barkley says nah. Well, he actually says nah and sense. That's nonsense. Nonsense. First of all, those things are not sufficiently accurate to diagnose ADHD,
Starting point is 00:58:18 even though their test developers will tell you they are, they're not. And secondly, they're misleading because half of adults with ADHD can pass those tests and still be legitimately ADHD. So I just tell people, forget the test scores because a lot of the time they're wrong and the history tells the story.
Starting point is 00:58:37 Plus, as you pointed out, we need to interview people who know you well. That's part of our diagnostic criteria. We need to corroborate what you're telling us through other sources. Hopefully that's gonna be your parents or siblings or good friends or a spouse or a partner. But in some cases, all I have are the archival records,
Starting point is 00:58:55 your school report cards, your driving record, your work record, your criminal record. All of those are things I may need to take a look at in order to look for evidence that this has been a longstanding problem for you. So yeah, it takes time. But as I said, no less than two to three hours. And you have a whole section in the book,
Starting point is 00:59:13 which I think is great about finding a clinician too, which is so helpful. Do you ever have to recommend to people who either have a diagnosis or don't? Like if they're going to digest literature on this, is there a preferred way to do it? Like as you take notes, audio, like what's the best way? Well, I tell you what we heard from people
Starting point is 00:59:33 when I was writing the book. And we actually field tested that book. If you look at that book compared to all my other books, it's organized vastly differently than my other books. And the reason is we field tested the manuscript on adults with ADHD. And that's why you see that it's all broken up. There's little sidebars and there's glitzy little microscopes
Starting point is 00:59:54 and there's call outs and bold emphasis. And it's enough to drive a typical person crazy when they look at this thing. How do you pay attention to this? Because they're used to reading like continuous prose and narrative. And this is so far from that, as you know. So that was field tested.
Starting point is 01:00:11 We found that at least if you're going to read, that captured your attention better than typical narrative does. Well done. The second thing that we do, of course, is a lot of adults tell me that the e-book is better for them than that. I also get five to 10 emails a day of people saying,
Starting point is 01:00:26 I discovered you through your YouTube lectures. And that's the first time I was actually able to sit through and listen to this stuff. So maybe now I'll go and get the e-book or look at some of your podcasts that you've done with other people like you and start to pick it up that way. And then eventually they wind up back at the book. But we understand that reading is very hard for adults
Starting point is 01:00:47 with ADHD because of their working memory problems. They can't retain what they read the way other people can. And they find themselves mind wandering while they're reading. And then they got to go back to the top of the page seven times. So I understand, I get it, that text isn't always the best way for adults with ADHD to learn stuff. I was looking through the e-book and I was so excited to see like, oh, there's a post-it note in a sidebar.
Starting point is 01:01:12 And it really does kind of engage it. And I've even heard you say, leave post-it notes for yourself, have them be different colors. Something that engages you and is novel will help. And obviously we got to go back and we got a lot of questions from listeners ahead of time. Literally the most questions ever. So to avoid overloading you with names of patrons,
Starting point is 01:01:33 I'm just going to read the names of first-time question askers for some of these. But before we do, let's support some causes that are supporting people with ADHD. So donations for this and next week's episodes are going to a few places. Namely, for this episode, Chad, children and adults with attention deficit hyperactivity disorder, which
Starting point is 01:01:50 has local support groups in every state in the United States and offers assistance for parents, children, young adults, and adults via advocacy and support and networking and information. More information about them is available at chad.org, 2Ds and Chad. We're going to be donating to a few more places next week as well.
Starting point is 01:02:10 All of that was made possible by sponsors of the show, who you may hear about now. OK, without further delay or distraction, your questions. So as a person with anxiety, I found it soothing that so many of you asked about anxiety and ADHD or other comorbidities. So I'm looking at you. First-time question askers, Becky Niesel, Aurelia,
Starting point is 01:02:31 Heather E. Stewart, Allison Bardsley, Xenia Holm, E.J. Warner, Britt Klein, Annabelle Marks, Dan R. Wynne, Keelan Jackman, Sarah Albrecht, Maya Rupnerin, Aaron Simino-Ozowski, and Adelaide Mezunov, not Ms. Innaueve, like I said last time. They all had a common question. One thing that I thought was really interesting, we got a lot of, was like Becky Niesel says,
Starting point is 01:02:56 I'd like to know some differences between general anxiety disorder and having ADHD. They have a lot of the same symptoms. Skella, Stephanie, a bunch of people asked about this. How do you parse that out during diagnosis? Right. Well, I think superficially people would assume that because there are attention problems that
Starting point is 01:03:13 go with anxiety and depression. And so people automatically think that all attention deficits are ADHD, and that is way over simplifying. We now know that there are at least two, and eventually there'll be five. But at least there are two kinds of inattentiveness. The one that goes with ADHD is being externally distracted. So I'm skipping from one thing to another.
Starting point is 01:03:34 And all of the irrelevant events going on around me are pulling me in various directions. So I am overly coupled to my environment and not coupled enough to my mental information about my goals, my plans, my due list, the things I said I was going to do today. I'm not governed by mental information the way other people are.
Starting point is 01:03:57 I'm overly governed by context and the now. And so that's ADHD. Now let's look at anxiety and depression. What we see with them is the opposite. They are overly coupled to mental information, rumination, obsession, fear, anticipation, worry. Sounds like fun. So they're inattentive,
Starting point is 01:04:19 but they're going to be inattentive in a staring, daydreaming, mind wandering kind of way. Like an absent-minded professor, they're not hyperactive. They're not distracted. They're just in their head way too much. And ADHD people are not in their head that much. And if they are,
Starting point is 01:04:37 it's because their ideas are skipping all over the place. So the two disorders are not that hard. I mean, ADHD does not lead to fear, worry, anxiety initially. Now, after about 10 to 20 years of not being treated, anxiety disorders begin to become a coexisting disorder with ADHD such that by the time you're in your 30s, 35 to 50% of adults with ADHD have developed an anxiety disorder.
Starting point is 01:05:05 But that's because of the chronic failure that ADHD is leading to. So you don't have to fail in social situations or at work too many times before you get really anxious in those environments. But that's a different kind of anxiety that comes from overexposure to negative consequences and even traumatic consequences
Starting point is 01:05:28 that other people don't experience. On the other hand, if you have a legitimate anxiety disorder, yours is much more forward-looking. You are over anticipating punishment, negative consequences, what people think about you, that you're gonna die when you get in the car, that your parents aren't coming home
Starting point is 01:05:45 and they leave the house, those are anticipatory anxieties. And that's not what we see in adult ADHD. Adult ADHD, it's more learned anxiety. So one is driven by the past. That is, I frequently fail in this situation or it's driven by the working memory deficit. There was a photographer in Atlanta who put it beautifully.
Starting point is 01:06:05 He said, I'm out on a photo shoot and I can't remember whether I agreed to pick up our five-year-old a daycare today or my wife. And it's four o'clock. So the kid's been out of school an hour. If he's sitting at a curb with his teacher, because I'm not there, and he freaks out, okay? So you see what I mean?
Starting point is 01:06:23 He's questioning his memory, his forgetfulness because it's happened before, you know? These are the people who get out of the car and leave the car seat on top of the car and walk into work and it's like, wait a second, right? Your kid's on top of the car, right? Because they're just so distracted by everything going on around them
Starting point is 01:06:45 that, you know, as I say, the now pulls them along by the nose. And so that's a lot different than somebody with a legitimate anxiety disorder. But understand that by the time you're in midlife, the two disorders go together more than we like to think. Now, who out there questioned the role of gender and assigned sex at birth in diagnosis
Starting point is 01:07:07 or hormonal influences? So many first-time question askers, Brittany Twenter, who said, I would love to hear more about how women and girls often go undiagnosed. Alyssa Williams Pierce Marisol, Brynne Roman Robin, Dakota P. Alley Vessels, Rosalyn Hesby, Rebecca Hatherly, Kira Elizabeth Trailer, Kieran Robinson, Kaitlyn Heidi Wismith, Layla Green Touche,
Starting point is 01:07:27 and Tara Allen, who wrote, it would have been awesome to know sooner. Elle Ann Eva Hayozova, who just, who wrote, OMG, OMG, OMG, this is exciting. Do you ever see that there is a gender bias in terms of diagnosis where maybe girls would be diagnosed with anxiety or boys ADHD? Yes, it's getting better.
Starting point is 01:07:48 But I have to tell you that girls were the silent majority for many years. Back in the day when I came in, it was six to seven boys referred for every girl. That's now falling down to about three to one, which is about the legitimate sex ratio. The disorder is more common in little boys than little girls. But having said that, right,
Starting point is 01:08:05 girls were not getting referred even when they had legitimate disorder. There are various sociological reasons for that that we don't need to go into because people might find them, although they're factual, they're offensive. People worry more about their sons and their daughters because the bottom line is you can always
Starting point is 01:08:23 mirror your daughter off, but your son has got to become independent. Now, life has changed. I'm speaking back in the 60s and 70s when that was clearly the case. Just a heads up, this is a little fun fact. So until the Equal Credit Opportunity Act, a bank could refuse a credit card to an unmarried woman,
Starting point is 01:08:42 but if she was married, it was okay. Her husband just had to give permission and cosign. This was in 1974, years after we launched human people in rockets to the moon. Ladies could finally get their own bank accounts. Feel free to break something, but don't actually, because of emotional dysregulation,
Starting point is 01:09:01 but you know what I'm saying. So there were various reasons why girls just didn't get referred. The other thing is that girls are less hyperactive and aggressive, and nothing will get you referred faster to a mental health clinic than being a pain in the ass, and the boys are just a pain in the butt. And so they got referred,
Starting point is 01:09:17 whereas the girls are simply chatty cathies. They're the social butterflies not doing any work, flitting around drama queens, but none of that gets you referred because you're not punching anybody. You're not talking back to your teacher, you're not so defiant. So the girls kind of got overlooked
Starting point is 01:09:34 because they tend to have less of the hyperactivity, a little bit more of the inattention than the boys do. But that is changing. We now get it. I mean, virtually every week, I'm seeing three to four articles in my news feed on girls and women with ADHD. So hurrah, you know,
Starting point is 01:09:48 the information's getting out there. Another reason for the girls being overlooked is, as I said, the disorder occurs three times more often in boys and girls. And so it's hard to spot it in a girl, and a girl has to be more severe to get referred and treated. But there was another reason for that.
Starting point is 01:10:07 We now know that girls have kind of a two-phase onset. There are some girls whose onset is in childhood like the boys, right? And they tend to be pretty bad cases. But there's a second wave of onset at the onset of puberty and menstruation. And we're now realizing that female hormones and their balance play a role in exacerbating ADHD symptoms
Starting point is 01:10:28 in women. And so we have a second wave of onset of girls who were kind of marginally ADHD in childhood who hit their menses and now are full-fledged women with ADHD. And each month, as their cycle comes back around, are gonna have three to five days of exacerbated symptoms that clinicians have to deal with,
Starting point is 01:10:48 particularly with regard to emotional dysregulation and their forgetfulness. But the emotional ones, you know, tend to be really exacerbated by these changes. And now let's fast forward, you're 55. Now you're going through perimenopause. And we now have women coming in who are marginally ADHD who are just fallen apart in their mid to late career
Starting point is 01:11:12 because of perimenopause and the changes. So there are some great articles coming out now on the impact of the imbalance of estrogen and progesterone on women with ADHD. So like I said, we're catching up, more girls are being referred, more girls are being treated, more girls are being put on medication than ever before.
Starting point is 01:11:32 And that's all good news to me, but it's also to say, you know, we still get a ways to go. There are some differences. The disorder is the same between men and women, but the comorbidities are not. Girls tend to have more anxiety depression, boys tend to have more conduct problems, anti-social behavior, defiance, risk-taking and drug use.
Starting point is 01:11:53 And although the girls can show those things too, for the girls, it tends to be more of the anxiety depression. And of course, we know there are many genders, gender can be on a spectrum too, but this is speaking broadly about people assigned female at birth. And those with ADHD who are raised as girls also tend to show higher rates of self-harm,
Starting point is 01:12:14 including disorder to eating, which can be completely missed. Now, speaking of things we have to do every day, the take foresight and planning and task initiation, food. What should you be eating? How do you eat if you have ADHD? So in Dr. Berkeley's book, Attention Deficit Hyperactivity Disorder, a handbook for diagnosis and treatment,
Starting point is 01:12:35 he wrote, essential fatty acid supplementation may make a difference in ADHD symptoms, but more research is needed. And he also notes that two pilot studies suggest that low iron levels can exacerbate ADHD and supplementation can help. So if you listened to the microbiology episode, you might be wondering,
Starting point is 01:12:56 how do my simmering waste-filled guts feel about all this? Or rather, how do they make me feel? Well, patron Gwen Kelly inquired, is there any research connecting microbiome and ADHD? And in fact, I dug in, I got in the muck and I found a study published just last month in the journal Nutrients. And it was titled Current Evidence on the Role
Starting point is 01:13:19 of the Gut Microbiome and ADHD Pathophysiology and Therapeutic Implications. But it warned, evidence of the role played by the microbiome gut brain axis in ADHD is still scanty and heterogeneous. So it's all the fuck over the place. And it went on to say, in children and adolescents with ADHD,
Starting point is 01:13:41 that microbiome gut brain axis is involved in the pathophysiological mechanisms of neuro-inflammation. Thus, the gut microbiome could represent a potential therapeutic target in children and adolescents with ADHD. But sadly, very womp-womp trombone, it noted that inconsistencies were found among the three supplementation clinical trials
Starting point is 01:14:05 on children with ADHD. So they haven't quite cracked the code yet. There's this diet though called the Fine Gold Program that just kind of wipes your plate of any artificial colors and flavors, sweeteners or preservatives. But not all research on it can be replicated. Many experts are like, on the fence.
Starting point is 01:14:25 But research has shown that about five to 8% of folks with ADHD may have sensitivities to those things, but it can be a heavy burden to have a diet so strict. Patron Adam Weaver asked, why does red dye number 40 really set things off for my ADHD? How about additives? We got questions about like red dye. Does that have an impact on brain chemistry?
Starting point is 01:14:47 Scientifically, there's a minuscule amount of evidence to show that among preschool children, about 3% to 5% of them are exacerbated if they're exposed to a food coloring. It's not additives, it's not preservatives, it's not flavorings, it turned out to be food coloring. So I don't wanna just throw the baby out with the bath here. There's a little bit of information out there
Starting point is 01:15:09 that does show a reliable exacerbation, but primarily in preschoolers. So there's a little bit there, but that doesn't mean you should go around consuming this stuff, but we have found nothing in the diet that is causal of ADHD that can turn a typical person into an ADHD person through sugar or additives or plastics or any of those kinds of things.
Starting point is 01:15:31 So Dr. Sandy Newman is one ADHD practitioner who advocates for balancing your diet and recommends sussing out food sensitivities to see if it has any effect on your noggin. And he's written a bunch of articles and in one writes, quote, try this technique I use with my patients. Eliminate a whole set of foods,
Starting point is 01:15:48 dairy, wheat, corn, soy, eggs, or common culprits for three weeks. And if improvement is detected, start adding the foods back one by one for a couple of days. I usually recommend starting with gluten first, he writes, and give it three to four days and see if there are any developing behaviors associated with each food.
Starting point is 01:16:07 The process should take six weeks and all. You can do it. Now, if no improvement is detected, then food sensitivities are likely not an issue. So if you've been meaning to do like a whole 30 or something, maybe this is your cue. I say to myself, pointing at my own face, ask me if I watched people making paleo pad Thai
Starting point is 01:16:30 at a spaghetti squash on TikTok at 2 a.m. last night. I did. Now, speaking of that, a bunch of patrons asked about screens grabbing our attention. And I'm looking right at you, Bailey Ricketts, Heather Wills, Daphne McKee, and Coral Taylor. Does Dr. Barkley have any thoughts? Of course.
Starting point is 01:16:47 And it's not screen time, by the way. The idea that the more time you spend with screens and computers, the worst that makes this, people think there's an acquired ADHD because of technology. There is no evidence underlying that particular mythology. It's the other way around. People with ADHD gravitate toward engaging technology and are more engaged by it
Starting point is 01:17:09 because of its highly reinforcing property. So they're on social media. They're internet gaming. They show internet addiction that other people are able to pull away from and lead a more healthier, better regulated life. So the chicken and egg has been pretty much sorted out. And ADHD leads to abuse of screens and technology,
Starting point is 01:17:30 not the other way around. So if you do have a problem with too much screen time, maybe you could do it safely on a treadmill, like the old indoor scroll and stroll. Laura Stacey wants to know, they were diagnosed later in life and have found certain things especially helpful, a big one being movement and exercise.
Starting point is 01:17:48 Is there any research on the effects of exercise on ADHD? Yes, there is. Over the last decade, it started out to be a sort of a clinical observation. A lot of us began to realize that our kids were better on the days they played sports. They're better after recess. And so people started exploring this.
Starting point is 01:18:04 And then we realized that both what I call macro movement, you go for a run, you go out and climb three flights of stairs before you go into a business meeting, you play sports, that's great. That research shows that that is very helpful for managing and containing your disorder. It doesn't buy you cure,
Starting point is 01:18:23 but it can reduce your symptoms for 45 minutes to an hour and a half by engaging in vigorous activity. Now what we're realizing is even micro movement is helpful. So for instance, if I go into a business meeting or I have to listen to somebody who, I have an educational video, for instance, as an example, you are better off squeezing a tennis ball with one of your hands or taking notes
Starting point is 01:18:46 or standing and pacing while you do that. So stay in motion while learning and you will be able to pay attention longer than if you have to sit like a cadaver with your hands in your lap and your head forward and now you're a dead person. I'm dead. And we now have a number of schools that are adopting this
Starting point is 01:19:04 where kids are allowed to sit on balance balls and they've got little swings under their desk, they can put their feet on and they're allowed to have a stress ball on their left hand and they can stand and sit on their knees and walk around their desk while they're working and all of which leads to better productivity by these people.
Starting point is 01:19:21 So the answer to that question is yes, exercise helps and we're learning that increasingly now. And your pod mom, Jared says exercise definitely helps him, the kinds that work the best for him also engage his brain like martial arts or weightlifting with actual good technique as opposed to how I weight lift, which is just poorly looking like someone scrambling up a hill with luggage.
Starting point is 01:19:50 But do you have pet peeves with exercise? Jared says team sports, like being stationed in the outfield, having to stand there with a mitt and just wait for something to fly your head while a collection of screaming people are like, we're relying on you, don't mess it up. Those are his least favorites. There's also running and listening to podcasts.
Starting point is 01:20:12 Hey, what about the sport of hidden the sack? So patrons, nano naturalist, Lungox, Janelle Shaw, Carter Hildebrand and first time askers, Feuderich and Stacy Simmons all had sleepy bedtime questions as well as Celia LeBont want to know they were diagnosed at 26, but they want to hear about sleep procrastinating in the intersection of sleep and ADHD
Starting point is 01:20:34 and how ADHD can fuck up sleep patterns, but in just procrastination in general. Well, I'll view those as separate because sleep procrastination is also insomnia. So let me deal with the sleep issue first. 40% of kids and adults with ADHD have serious sleep disruption. So that goes with the genetics of this disorder
Starting point is 01:20:55 and it can be difficulties with falling asleep. It can be frequent night waking. It can be restless like syndrome or just restless sleep. It can be early rising, all of which leads to at the end of the night very inefficient sleep leaving you tired the next day which feeds back to worsening your already terrible attention span
Starting point is 01:21:15 because now you've got sleep interacting with ADHD in attention leading to problems. On top of that research, particularly in Holland by Sandra Kui and others has shown that people with ADHD get a different version of the clock gene which is the gene that determines your sort of mental tempo and your peak hours of alertness and arousal. So adults with ADHD tend to have a peak time of arousal
Starting point is 01:21:40 three to four hours later than typical people. Typical people, it's mid to late morning. Adults with ADHD, it's mid to late afternoon. And so sometimes what we teach you to do is to play around with that. Can you get a flexible work schedule? Are you better off going into say self-employment where you can alter your schedule
Starting point is 01:21:58 or working from home and having a flex schedule with your boss but understand that the disorder has created in you a delayed diurnal rhythm so that your peak times of concentration are not the same as other people. And trying to manage that with caffeine is not good because it doesn't help all that well and trying to cope with it by simply saying,
Starting point is 01:22:18 well, I just need to learn better ways to fall asleep. Well, I'm sorry, biologically you're not programmed to fall asleep when other people do. For more on this, you can see the double somnology episodes on sleep or the chronobiology episode on circadian rhythms and why you should make sleep your number one priority, always and forever, sleep your number one crush,
Starting point is 01:22:40 oh my God, the best, sleep is king or queen or full, even twin or couch, sleep is couch, whatever is good is good for you. So that's all by way of saying that, you know, a lot of times we have to address that sleep problem through other means, whether it's through another medication, whether it's through switching away from a stimulant because stimulants cause insomnia
Starting point is 01:23:04 whereas the non stimulants don't. Maybe we have to send you to a sleep lab for a 24 hour, you know, polysomnogram where we look at your rhythm day and night but particularly during sleep to see if it's inefficient. We know that about, you know, 10% of the people with sleep problems, it's due to obstructed airways of tonsillectomies are indicated
Starting point is 01:23:25 and result in significant improvement in children and possibly adults but it's more of the researchers on kids. So if you're snoring a lot, if you have sleep apnea then we want to look at how do we expand that airway surgically or otherwise and you can find that that improves sleep and then the kids are better the next day.
Starting point is 01:23:44 So there's a lot going on around the sleep thing that I don't wanna oversimplify and it isn't just procrastination, there really is a diurnal rhythm problem here with alertness. Now that said, procrastination is probably the number one problem that adults with ADHD report as part of their attention deficits.
Starting point is 01:24:03 So, okay, side, we did touch on this in the evolutionary psychology episode and Dr. Joseph Ferrari leading expert in the world on procrastination said this. I hesitate to say this because sometimes people get very annoyed with my comment but there's only been one study that looked at procrastination and ADHD and I did it
Starting point is 01:24:23 and I found practically no relationship. Really? And it's true that the procrastination or volitional psychology community hasn't done a ton of studies on this and the one that Dr. Ferrari mentioned was the paper procrastination rates among adults with and without ADHD, a pilot study
Starting point is 01:24:40 and it was published in counseling and clinical psychology in 2006 but the study involved 29 people most of whom were married with children, well-educated, white collar professionals living around the same Midwestern urban area. All white too. Median age, 49 years old
Starting point is 01:25:01 and all active in a support group for adults with ADHD which I personally have been meaning to attend for years and haven't gotten around to it. But even then, this small really limited study found that adults diagnosed with ADHD reported significantly higher decisional procrastination and avoiding procrastination. So this was his study, I don't know.
Starting point is 01:25:25 I count that as a relationship and thankfully more people want answers because a 2021 Frontiers in Psychology article acknowledged that few other studies exist but found that yes, chronic procrastination occurred more frequently in ADHD patients than those without ADHD, regardless of gender. And I found an article by another procrastination expert,
Starting point is 01:25:46 Dr. Timothy Pitchell who noted that fear of mistakes and fear of boredom can contribute to procrastination in folks with ADHD. And that a good reminder when it comes to a task you're avoiding and you just do not have the motivation to start that it doesn't have to be perfect. Leaving yourself time to come back later and revise can really take the stakes down.
Starting point is 01:26:09 And next week we have some really, really great tips about that but what does Dr. Barkley say works for procrastination? A lot of life and a lot of work we're asked to do is scut work that isn't very reinforcing to engage in. But if you don't get it done, there's gonna be hell to pay. So the consequences for not doing it are longer term whereas the thrill of doing it is absent.
Starting point is 01:26:33 And hence, as I said, the adult with ADHD is pulled along by things that are immediately gratifying more than things that involve delay of gratification. And that's why work is very hard for them and why they procrastinate so much is that there are plenty of things around us that offer engagement, excitement, reinforcement, interest, stimulation.
Starting point is 01:26:54 And yet a lot of what we have to do in life is to turn away from those seductions and pursue that longer term goal even though it's not very fun to do. And so how do we deal with that? Well, one is medication, medications correct that. What the stimulants do is they enhance the reward value of this information so that now you engage it
Starting point is 01:27:16 where you didn't previously. The second thing is, as I've said, to make sure that you've managed your workspace and reorganized it. So a lot of the more compelling distractions are not there. They're not available to you. The third thing is we know making ourselves socially accountable to somebody else
Starting point is 01:27:33 what we agree to do heightens the likelihood we're going to do it. That's true of typical people, it's true of ADHD people. So if I tell somebody I'm gonna get this done in the next half hour, just making that commitment to another person enhances the consequences for me, makes it more likely that I'm going to get it done.
Starting point is 01:27:53 Dr. Ferrari's advice was post your goal on Facebook or Twitter or tell a friend because just that a whiff of potential future public shame can really get the job done. Go on your crush's Facebook and just be like, hi, I'm going to vacuum my car today. I bet you'll get it done. You're now accountable to someone else
Starting point is 01:28:15 for what you agreed to do, whether it's your coach, whether it's a spouse, partner, colleague. That's why public accountability is a great strategy for adults with ADHD, because it ramps up the consequences for not getting it done. Whereas if you just promise yourself you're going to do it, you're going to cheat yourself.
Starting point is 01:28:31 We all do it, you know. If nobody knows I'm cheating, then I'm going to cheat, right? And I'm not going to do it. So it really is learning to know thyself and where the demons are and get them behind you, so to speak, get them out of the way and use other people to manage yourself.
Starting point is 01:28:52 And you'll be doing, and then go on medication. There's a lot of strategies in my book that we could go through, but that can help. Oh, and hey, some patrons like Mackenzie Foss and Michelle Krebs, Kelly Salmon, Heather Moore, team Morris and first time askers, Aaron Spencer and Dave, don't worry. I did not reject her questions.
Starting point is 01:29:10 They were good ones and they were super important to me, as well as to post-officer 69. Can I ask you one more question from a listener? Post-officer 69, first time question asked her, says, could you have Dr. Barkley discuss rejection sensitivity in relation to ADHD? I'm trying to learn as much as I can to better support my fiance.
Starting point is 01:29:28 That's great. Number one, there is no such disorder in clinical practice that is officially recognized. So this was invented by a particular clinician to explain the heightened emotion that people experience in their social relationships with others, particularly when those social relationships can be frustrating.
Starting point is 01:29:51 And so you get this, what he calls rejection sensitivity. But there is just no this, there's no disorder, no clinician will diagnose you with that because there's no DSM disorder there. So sensitivity to rejection and criticism is a thing that very, very, very much exists and folks with ADHD may be much more vulnerable or reactive in that regard.
Starting point is 01:30:14 So is RSD, rejection sensitivity dysphoria a specific disorder that you have? No, just because it's not recognized by the greater psychological and neuroscience community in a book. So there's not a consensus on it yet, there's not a label that actually exists. Who knows what might change though,
Starting point is 01:30:34 but the feelings are real and this is just my opinion, your internet dad with unbrushed hair and a lot of been there feelings. If rejection sensitivity helps you to put your own emotions in perspective or calms you when you need some objectivity or helps explain to a partner why you are so clinically but hurt, use it.
Starting point is 01:30:57 Knowing how to soothe each other and see vulnerability and hurt is probably one of the greatest tools that your relationship can ever acquire and maintain. I call it a win and Dr. Barkley concedes that yes, those feelings are valid. On the other hand, do people with ADHD show a heightened emotional reaction in these situations? The answer is yes, but we know where that comes from.
Starting point is 01:31:20 One of the executive functions is emotional self-regulation and we know that ADHD individuals can't do that as well as other people. And therefore when they are faced with environmental situations that are frustrating, impatient, non-rewarding or even aggressive toward them or where they sense rejection from another person, they're going to react emotionally
Starting point is 01:31:44 much more than other people do, but it's not just two social relationships. It is across the board. They're gonna be more emotional even when they're alone and encounter frustration. I mean, I had a weight lifter tell me that he tore the door off of his car because when he parked it went into the parking lot,
Starting point is 01:32:01 he left the keys in and he locked the door. Now this is back old school days where these days are very hard to do that because cars are programmed to do that. But this guy literally spent 30 minutes by the side of the road in a parking lot tearing the door off a car. That's how angry he got.
Starting point is 01:32:16 Road rage is characteristic of 40 to 55% of adults with ADHD. All it takes is another driver to cut you off aggressively and you engage. And so the emotionality of ADHD permeates almost everything. It explains why there's a lot more intimate partner aggressiveness and frustration in intimate partner relationships because they can be some of the most challenging
Starting point is 01:32:39 and frustrating and emotional situations that we have. Does your partner have ADHD? Or do you, the book, The ADHD Effect on Marriage by Melissa Orlov is a book you may want to get yesterday. Even if you're not married, Jarrett and I wouldn't be married if we hadn't both listened to that book in 2017, I think it changed our relationship. So fundamentally, we would not still be together
Starting point is 01:33:03 if we hadn't both listened to it at our own pace on audiobook. We listened to it about the course of a week or so. It helped us a bunch. So The ADHD Effect on Marriage, I'll link it to my website. So it goes beyond just rejection by another to incorporate any emotionally provocative situation,
Starting point is 01:33:23 including relationships, but beyond relationships. So we can account for this rejection sensitivity without adding in and inventing whole cloths, a new disorder for which there is very little evidence. So Dr. Barkley is a world-renowned expert on this and his work and lectures have changed and saved lives. And next week, we'll give the bright sides and the tips and the perspective on ADHD.
Starting point is 01:33:50 In this episode, we learned to take it seriously. What sucks about his job? Worst thing about my job right now is I'm 72 and I see the end of my career ahead of me. And, you know, it's been a great ride. I just can't tell you how rewarding it has been to work in this field. It's why I wrote the four books during the pandemic.
Starting point is 01:34:13 I, the one for parents, the 12 principles book, I basically sat down and said, if you could reduce over a half million research studies, papers, conferences to crucial ideas that we've learned that everybody needs to know, it would be those 12. And the adult taking charge has the same information. I just didn't phrase it that way. So, you know, the bad thing for me is I can see this coming
Starting point is 01:34:36 and I'm stepping back and I'm moving into semi-retirement and enjoying my grandchildren, but I'm gonna miss the ride. It's been extremely rewarding to be this helpful to so many people through the act of scientific discovery. And more importantly, as Carl Sagan and others have shown, is to disseminate it, leave the lab. I keep teaching this to students and young faculty. You do nothing when you publish a paper.
Starting point is 01:35:04 You do a great deal for humanity when you go out and meet with the people who have this problem and share the science, disseminate it, and you change lives that way. And yet, my colleagues don't value that. They value the publication, you know, the scholarship, whereas if you write a trade book, if you give a lecture, like my lecture on YouTube, is over a half million people,
Starting point is 01:35:32 you know, so disseminate the science. The upside for me has been just the excitement of the discoveries. Every time I think I'm getting bored, a paper appears like the one yesterday on, you know, the delay in functional connectivity in the brain and the areas of the brain and what that means for their symptoms
Starting point is 01:35:53 and explaining the disorder and what it might mean for new treatments for us. You know, to me, that's just, it's so incredibly exciting to an inquisitive person like myself to keep seeing these discoveries coming along. Thank you so much for the way that you do disseminate it. Your books are incredible.
Starting point is 01:36:13 They are the Bible when it comes to ADHD. Well, I gotta thank Chris Benton, my co-author. Chris, you know, she's my, she's my writer. She makes it sing. You know, I just, I bring the science. She brings the way to deliver it. So ask experts some amateur questions because as you heard, they wanna share it.
Starting point is 01:36:33 And besides, we're all gonna die one day. You might as well just ask questions. I hope this episode is a springboard into greater understanding for you. So next week, more experts, more folks with ADHD and people who study ADHD, just you wait. You do have to wait though, about one week, okay. Now, if you need more info now though,
Starting point is 01:36:52 you can get yourself to a bookstore and obtain taking charge of adult ADHD second edition. So that's by Dr. Russell Barkley. Just came out with a brand new updated edition in November. There's so many links to his books and studies we mentioned and other resources, including his videos. That'll all be up at alleyward.com slash ology slash ADHD.
Starting point is 01:37:12 Russell's website is russellbarkley.org. And from what I can tell, there's a weird imposter Twitter account. That's not really him, but we're at ologies on Twitter and Instagram. I'm at alleyward with one L on both. Come say hi. Thank you to the ologies podcast subreddit.
Starting point is 01:37:29 Thank you to Aaron Talbert for admitting the ologies podcast Facebook group and Bonnie Dutch and Shannon Peltis at the podcast. Do you wear that for helping out to you? Noel Dilworth helps so much behind the scenes with scheduling, so many meetings I would miss without her. Susan Hale does merch and helps
Starting point is 01:37:45 with those really cool Instagram quizzes. Emily White of the Rotary makes professional transcripts. Caleb Patton bleeps them. Transcripts and bleeped episodes are up for free at alleyward.com slash ologies dash extras. And for truly kids safe episodes, check out Smologies. Those are in your feed every few weeks and they are scrubbed of my filth.
Starting point is 01:38:05 Thank you, Zeke Rodriguez-Thomas of Mind Jam Media for heading those up and Stephen Ray Morris for helping them out. Major thanks, huge thanks to lead editor, right hand in the most glimmering, shiny, beautiful, big brain I know, Jared Sleeper. Also of Mind Jam Media for editing it all together and making it work every week with me.
Starting point is 01:38:25 Nick Thorburn wrote and performed the theme music. And also if you're a patron or you're thinking about joining, I'm gonna be doing a live stream on Patreon, March 6th, Sunday at noon, California time, just to chat about the making of this episode and some brain stuff I personally have been going through in the last few months. Oh, and you can check out the Women in STEM panel
Starting point is 01:38:47 on March 3rd. It's through the California Academy of Arts and Science. I'll be moderating a live chat in person for the first time since March, 2020. And you can see that online. That's March 3rd at the California Academy of Arts and Science. Also special thanks to Matt Schep, who's on TikTok.
Starting point is 01:39:02 He was also my server over the weekend as I was posted up at a restaurant and I sipped one latte for four hours working on this episode. And he asked if he would get a thanks and a credit and I was like, yes, you will actually. So thank you, Matt Schep. If you stick around to the end of the episode,
Starting point is 01:39:16 I tell you a secret. And that secret is there's been this street light outside my window for maybe a year and it was gradually turning blue-ish and then a deep, beautiful violet. It was such a weird color. And I was like, what's going on with the street light? And I looked it up and I guess street lights
Starting point is 01:39:35 all over the country are just doing that randomly because of a coating over it that shifts the color temperature warmer, but that coating has been degrading, turning these lights super, super blue. But number one, a bunch of people think it's actually a black light conspiracy that's I think spying on you.
Starting point is 01:39:54 But number two, I mentioned it to my friend Mackenzie, this purple street light and we both confided that we love the messy purple ones. And this week I went to water the wildflowers in the garden we just planted and I looked up and I noticed that they fixed the purple light but I missed the purple light. I thought it was so cool.
Starting point is 01:40:12 Okay, next week, productivity hacks, relationships and neurodiversity, life, work balance and boundaries on your energy and accepting yourself. I can't wait. Okay, bye-bye. Don't but me now.

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