Ologies with Alie Ward - Surgical Angiology (VEINS & ARTERIES) with Sheila Blumberg

Episode Date: November 27, 2024

Vaping and vein health! Covid and clots! Easy bruising! Movie blood! Spider veins! Free socks! The heroic vascular surgeon Dr. Sheila Blumberg of NYU Langone Health let me ask her one million question...s about how blood gets from point A to B all day. She explains the difference between arteries, veins, capillaries, and vessels and we cover everything from fainting to teenage movie tropes, how to tie a tourniquet, atherosclerosis, aneurysms, stents and why your leg is asleep right now. View Dr. Blumberg’s publications on ResearchGateA donation went to BreakingGround.orgMore episode sources and linksSmologies (short, classroom-safe) episodesOther episodes you may enjoy: Diabetology (BLOOD SUGAR), Field Trip: My Butt, Colonoscopy Ride Along, Functional Morphology (ANATOMY), Hematology (BLOOD), Surgical Oncology (BREAST CANCER), Biogerontology (AGING), Proptology (THEATER & FILM PROPS), Vampirology (VAMPIRES)Sponsors of OlogiesTranscripts and bleeped episodesBecome a patron of Ologies for as little as a buck a monthOlogiesMerch.com has hats, shirts, hoodies, totes!Follow Ologies on Instagram and BlueskyFollow Alie Ward on Instagram and TikTokEditing by Mercedes Maitland of Maitland Audio Productions and Jake ChaffeeManaging Director: Susan HaleScheduling Producer: Noel DilworthTranscripts by Aveline Malek Website by Kelly R. DwyerTheme song by Nick Thorburn

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Starting point is 00:00:00 Oh hey, it's that guy who watched your stuff at the library. So you could go to the bathroom, Allie Ward, and this is Ologies. And the lifeblood of the show is asking smart people, sometimes not smart questions. So let's take a trip through your vascular system for phlebology, which you will learn in a few moments is not a good name for the episode, because it does not totally encompass what thisologist does. So we had to figure some else out. And this guest is a vascular surgeon. And from what I understand, that is a very difficult job. And vascular surgeons have been called the surgeon surgeon. So if you're a surgeon who can impress surgeons,
Starting point is 00:00:33 I'm going to want to come to your workplace and ask you all about it. So this doctor is a clinical associate professor of vascular surgery at NYU Langone Hospital in Brooklyn, where she did her fellowship and residency after getting her MD from Boston University. And it said that what inspired her was having grown up in Kenya, where she saw access to high quality surgical care not readily accessible. So helping people has always been important to her, and she's very good at it.
Starting point is 00:00:57 So she's been on my list to help us learn about our circulation, and we're going to get there in a minute. But first, thank you to all the patrons who submitted great questions for this ahead of time and you can join that at patreon.com slash ologies it costs like a dollar thank you to everyone out there for wearing ologies merch from ologies merch calm and finding each other in the wild and of course thank you to everyone who leaves reviews which helped the show stay pretty cozy at the top of the science charts such as this one this was left by Fisker for who wrote ologies has quickly become my go-to podcast for every activity from baking
Starting point is 00:01:27 to drying to postponing a spiraling mental breakdown while I focus intently on centipede facts. And I gotta say Fisker4 that's a hell of a review to leave right as we splash down into an episode about blood tunnels. But I think everyone's gonna like it nonetheless. This is a great one. Also, reviewer save spiders, I see you and yes we have an arachnology episode in the works. Also if anyone's looking for kid-friendly episodes we have Smology's in its own feed which is linked in the show notes. It's great for car trips with the kids. Okay let's get into this episode. Get your knitting, fire up the lawnmower, put
Starting point is 00:01:58 your feet up for everything from vaping and vein health, why you can get a prescription for new socks, Scary airplane blood clots. Teenage movie tropes that are true. Using science for cinema. How to tie a tourniquet in a pinch. Spider veins. Arterial health. Atherosclerosis.
Starting point is 00:02:16 Stents. What is an aneurysm and how not to have one. COVID and clotting and why your leg is asleep right now. With NYU Langone. Vascular surgeon. phlebologist, as well as surgical angiologist and general medical hero, Dr. Sheila Blumberg. I used to. What's your go-to? When I had a good voice. I would try to do Aretha Franklin and tear the house down, but the less I sing, the better. The less I get good, so I can't destroy her songs anymore. I mean, you're still so good at it.
Starting point is 00:03:08 If you could do Aretha Franklin one time, I feel like you're gonna destroy it. Sheila Blumberg, she, her, hers. I've been wanting to talk to you for so long. This is very exciting. And would you say that phlebotaliology, is there an ology for this that you would suspect? Phlebology.
Starting point is 00:03:26 Phlebology. If that's specific for vein zoning, but then vascular also includes arteries, so that would, I guess, arteriology, but that's why we just say peripheral vascular. Okay, so vasculology has been used one time, but some countries refer to the study of blood vessels as angiology, meaning vessel in Greek. But angiology sometimes deals with the lymphatic system, which we don't get into, and angiologists are not always surgeons like Dr. Bloomberg. But since she is generously letting me ask her, a smart person, not smart questions,
Starting point is 00:03:57 and giving us a lesson in all things blood vessels, we're going to go with that. I mean the first question I'm sure a lot of people don't know including myself veins arteries capillaries What's going where? Okay, so those are all different sizes first of all okay decides whether it's a vein or a Capillary and then arteries are different pipes, so they're all pipes okay, so I'm a fancy plumber And so arteries are the main way blood
Starting point is 00:04:28 gets away from the heart. Okay. Those are the pipes that take blood away. Veins bring blood back to the heart. So arteries go away. A. Veins think V, valentine heart. And if the blood is leaving the heart going away via artery, it's ready for the journey with a full tank of gas. In this case, the gas is oxygen. Now veins are heading back to the valentine's heart on empty and they're returning home to the lungs for resupply of oxygen and then into the heart and out through, what are they going out through?
Starting point is 00:05:01 Arteries nice, sexy. Arteries carrying that oxygen rich blood are typically bigger than veins veins typically smaller smaller still though capillary bed is within the tissue and that's where veins and arteries meet and sort of form a web at a very microscopic levels who are talking microns and that's where the exchange of oxygen happens at the level of the tissue. And so the arteries come in to, let's say, your kidney and then go to the capillary bed, become smaller from arteries to arterioles and then capillaries and then the capillaries
Starting point is 00:05:38 exchange into venules on the other end and then the venules become veins. So the veins are the larger parts of things and that brings the blood back to the heart and so that's your circulatory system. So arteries, arterioles, capillaries, venules and veins they're all vessels or tubes that circulate blood. Now from biggest to smallest pipes we got small venules branched toward the full-size veins as they come closer to your heart. Veins have thinner walls. They're typically closer to the surface of the skin than arteries, and arteries are
Starting point is 00:06:11 located deeper in the muscles, and arteries have thicker walls. So oxygenated blood leaves the heart via the arteries. Artery literally means to keep air. It's kind of like a train system that leads to major stops in the organs and the tissues of your body. And then that goes down roads into smaller arterials, which go into teeny capillaries, which are like little trails to the tissues. And capillaries are around one tenth the width of a human hair. So tiny. And while you're minding your own business, you're eating kettle corn, you casually have 40 billion capillaries. You're magic. Can you believe that? 40 billion? You
Starting point is 00:06:51 have that. I hope you flirt using that fact. Are there capillaries that are so small, they're like single file in terms of blood cells? Yeah, they have to be because at that level, in order to exchange oxygen between the tissue, oxygen is just a molecule. It's have to be because at that level in order to exchange oxygen between the tissue oxygen is just a molecule It's got to be able to transfer itself across the bed of the cell layer to get to Whichever organ it's perfusing so there are almost less than a cell layer thick at that level Yeah, so extremely extremely small not visible to the human eye without a microscope. So it's been estimated that the human circulatory system would stretch out to be over 95,000 kilometers in order to pump more than 7,500 liters of your blood every day. By the way, that's 60,000 miles and 2,000 gallons, America.
Starting point is 00:07:41 To exchange it that quickly every second that we breathe and get blood through and the rate at which it's flowing it has to happen just like that so it's miraculous and in a way. Do our veins and arteries do they get less elastic or less robust or I guess hardening of the arteries is a situation? Yeah. What happens to us as we age? Do we start off with amazing veins and arteries and then they get kind of shittier? Well, yes, I think the aging process, unfortunately for arteries, they tend to become harder. And there's obviously lifestyle and environmental things
Starting point is 00:08:19 that we can do to make that worse or at least better. And so things like smoking and exposure to smoke and diabetes in general, those are the major factors in our environment and our lifestyle choices that end up hardening the arteries. And so you get plaque formation and then calcium deposits. And you can really see the calcium on imaging now, which they are doing more routinely
Starting point is 00:08:47 for coronary arteries in the heart to see what level of disease you have. You can scan it, you can literally see the whiteness of the calcium that's deposited there, so they get harder. That's not good because you want arteries and veins function well when they're softer and more compliant, right?
Starting point is 00:09:03 So they can squeeze and open as the heart beats and relaxes. The hardness, let's say, of the arteries is diseased. So that's unfortunate. And a lot of that's not reversible once it happens. What is the calcium deposits? Where are those coming from? They're coming from the bloodstream, essentially, right? So most of it happens over time,
Starting point is 00:09:28 and the exposure to things like smoking per se makes that layer in between the inner layer and the outer layer thicker. And so it essentially deposits in there, and the effect is calcification, yeah. So I'm so sorry. I'm sorry, but smoking can swell those inner walls, choking the flow and making it easier to collect plaque,
Starting point is 00:09:51 which contains cholesterol, cellular waste, clotting stuff called fibrin, and calcium that can cause atherosclerosis, which is a thickening or the hardening of the arteries. But again, since this episode would have been easier to name phlebology, but phlebology is only about veins, let's get more into it.
Starting point is 00:10:10 What about veins and arteries? Do they have different properties in terms of their structure? Yeah, absolutely. So veins at any point in time, 75% of your blood is in your veins. Oh, okay. The 25% is your arteries.
Starting point is 00:10:23 So veins have to have a high capacitance. They have to be able to hold that much volume and in a amount of time. So they're much more compliant, they're much more relaxed, and in order to get the blood back from your foot, right, back up to your heart, the way they do that is in a couple of mechanisms. They have valves on the inside. Arteries do not have valves. Valves are kind of like gates. They open, they let the blood go up, and they're supposed to shut tight so it doesn't drop back down. And so as blood goes up the column, it doesn't return distally, distally meaning back to the foot. What else happens is when we breathe, that also changes
Starting point is 00:11:02 the pressure gradient in the veins, so that also moves the blood up. So veins have to be compliant because part of their activity is by breathing. So every time you breathe, you change the pressure in your chest that allows blood to come through and come up. However, arteries. So arteries are not based on that. They're based on your heart, right? Because that's where their blood's coming from. So they have to be strong enough to take that pressure. So like, for example, if you're exercising, right? And you're a fairly young, your pressure can go up
Starting point is 00:11:35 to 200 millimeters of mercury, right? That's normal when we're exerting ourselves. And so arteries have to be tough enough to take that amount of blood pressure. So they're much stronger vessels in general. So they're thicker, more muscular. And so every time the heart beats, pumps blood through so they don't need valves or anything like that.
Starting point is 00:11:54 And in fact, valves would be a problem in an artery because they just gotta get the blood down across to all of our organs, meeting a lot of resistance. So the arteries have to be strong enough to do that and the heart provides that pumping action forward. So very different. And that upper number of your blood pressure is the force that your heart is beating that blood out
Starting point is 00:12:17 or down to your organs. And the bottom number represents the pressure when things relax in between the beats. You don't faint at the sight of blood, I'm guessing? No. No? That's been from a young age, so I'm in the right business. When you were going through med school,
Starting point is 00:12:33 was there a really big divide in terms of like, who could deal with a lot of blood and who was like, you know what, I'm really gonna be more of an outside doctor. More of an radiologist or something? No, I think most people who go into medicine have a capacity to deal with injury and or blood. So I don't think that's very common. I've seen it in lay people
Starting point is 00:12:55 who are not in the medical field so far. But I think what sort of sorts people out is what kind of fluids they can tolerate. So it's not just blood. I think blood is pure. It's clean. It's sterile. It's red. It's pretty. I like red. But some people like phlegm, forget it. Stool, forget it. So, you know, there's some things that everyone can tolerate. So I wouldn't do colorectal surgery because that's not for me. So I prefer blood. And so I think that's what sorts people out, is what fluid you can tolerate,
Starting point is 00:13:27 not necessarily an aversion to blood so much. Do you have to deal with that in your patients? Let's say if someone needs a blood draw. I know for me, I have to look away. And I was getting a blood draw once, and I looked away, I just averted my eyes. And I realized I was staring right into a reflective surface, and so I accidentally was watching at the same time.
Starting point is 00:13:47 But I fainted just cutting my finger, and I don't know why it happens, because I think my brain is like, you're going to die. But do you see that in your patients at all, anyone just keeling over? Oh, especially the blood draws. So even now, we have to be very good
Starting point is 00:14:03 about making sure most people are seated just in case they do pass out. They're already in a reclining position and we can sort of keep them safe from themselves. But yeah, it does happen. That's not uncommon actually. So we chatted with Dr. Joy Ridenberg, who's a functional morphologist who does whale necropsies. And the first time she witnessed a veterinary surgery she was so excited but then she straight-up fainted in the room with all these surgeons and she explained that she had what's called a vasovagal reaction which is an autonomic discharge of your nervous system that no one can predict is going to happen and when that vagus nerve is stimulated it causes a sudden
Starting point is 00:14:42 drop in your heart rate and also maybe the dilation of blood vessels to your legs, which causes blood to pool there away from your brain, causing you to pass out. And it can happen from standing too long or heat exposure, stress, the sight of blood in an anesthetized animal. And in April of 2020, when the pandemic was very fresh and people were having things like hobbies I tried whittling and within the first few minutes of attempting to craft a spoon I cut my finger and I fainted into the kitchen sink so what about when you're watching movies and you see a pool of
Starting point is 00:15:20 blood are you ever like that's notated, that is too much for what they hit? My commentary about movie blood is none of it looks really good. Why is that? I don't know what they use and I heard they use paste of some sort. I can't think of which movie had really good, maybe like Kill Bill, like Quentin Tarantino has good blood, but
Starting point is 00:15:46 the rest of them, and so I always like look at the characteristics of it and so I'm like, that's so fake. Like, so you don't, I don't particularly get gory about those kinds of things because it doesn't look realistic. Is it the viscosity or the color? Both. Okay. Yeah. So the only thing that looks accurate most of the time is old, dried blood. Like if it's an old crime scene, that looks more realistic because it's congealed at that point, right? So I think the fresh blood of when they cut people and they were sort of like spurting them like, really? No, I don't.
Starting point is 00:16:18 She's not wrong. I researched this for way too long. And according to a 2022 slash film article titled Quentin Tarantino only wanted the best blood for Kill Bill special effects. It says it's really difficult to recreate blood digitally and Tarantino prefers practical real life goopy effects. He also told a Time magazine reporter that quote, I'm really particular about the blood. So we're using a mixture depending on the scenes. I don't want horror movie blood. All right. I want samurai blood, he says. You can't pour this raspberry pancake syrup on a sword and have it look good. You have to have the special kind of
Starting point is 00:16:55 blood that you only see in samurai movies. Quote. So that's his take on it. And in yet another article at 2015 Vulture piece, there will be lots of blood. One of his producers divulged that Tarantino films require a separate blood budget and blood of such a specific range of hues that no other filmmaker is allowed to use it. And this range of bloods, plural, are under the label Tarantino Reds by the special effects house that furnishes his custom supply. He has a custom blood supplier. I hope this is a lesson. People make art, make science, make stuff. We're only here for a little bit. Life is short. Make stuff. Also, I was having a discussion with my favorite cheese monger today that French horror
Starting point is 00:17:38 director Alexander Aja has superb blood and I trust them. But back to Tarantino. Another one of his producers has described the director's blood use as different and balletic in the way that it moves and squirts and gushes. Does that happen? Because I always feel like you hear if you hit an artery you're screwed, veins are less of a problem. Is that true or is that complete nonsense? Well, that's to do with the pressure in the system. So arteries are high pressure, right? So when you cut an artery, the pressure at which it's coming out at you is high. So you're gonna lose more blood quickly. Veins are low pressure systems.
Starting point is 00:18:17 So if you cut a vein and you bleed, it's gonna be sort of a slow kind of ooze and more controllable. And the second thing is because veins, like I told you, are very soft and compressible, you're more likely to be able to control it just with pressure alone. You can call pressure an arteries and get pretty decent control as well, but that becomes the other part of it. Depending on which part of the body it is, you may not be able to compress it properly and that's why it can be more life-threatening obviously if you if you injure an arterial injury versus a venous injury yeah. So that's not flim flam. That's not flim. Okay and remember arteries tend to be deeper in the muscle so harder to compress so imagine trying to stop the flow of a garden hose under a tarp which is like a venous injury
Starting point is 00:19:02 versus crimping a fire hose under a mattress arterial. Now this is an exaggeration, but you get it. What about your work? What is a lot of your practice looking at? What is the, what's your day like? My day is, and this is why I've asked surgery, it's very, I do a very large venous practice. So that's a lot of varicose veins and venous ulcers and those kinds of patients. And then the other side of it with arterial disease, which is more sort of limb threatening
Starting point is 00:19:33 problems, right? So you have peripheral arterial disease where they're not getting enough blood flow to their extremity, most commonly to the foot. And this is why diabetics suffer from a lot of this. And then obviously, like I I mentioned smokers as well and those patients who are at risk of limb loss, those are the ones who obviously I get involved in and try to revascularize them, try to improve the blood flow to that area. For the venous patients, it's definitely not a limb threatening problem but it's definitely
Starting point is 00:20:02 a lifestyle kind of issue, right? Because people's legs do not function well if they have a lot of venous insufficiency where the veins and the valves have become destroyed for whatever reason. We call them incompetent now and they aren't able to get the blood out of the leg fast enough. They can start off with things, there's a swelling to begin with and then progress to skin changes where they start darkening their
Starting point is 00:20:25 skin because the blood is just pooling at the ankles and then the worst-case scenario for a lot of those patients is getting skin ulcers at the ankle because their skin has been damaged over time. So there's a spectrum of disease that we see in the venous space and each person sort of treated a little bit differently with that so every day is a little bit. So every day is a little bit different. Every patient's a little bit different. Every patient needs something a little different from the last patient. And when it comes to surgery, if you're doing surgery, especially on an artery,
Starting point is 00:20:54 which is high pressure, that I just learned that, are you having to clamp them off at either end? How do you stop someone from just bleeding out if you cut into that thing? Right. So typically we have control. So vascular surgeons, we love getting control of things. So it's usually above and below where the hole is, regardless of where that is in the body. And once you have control of it,
Starting point is 00:21:16 you can actually take a beat and just repair what you need to. And there's various ways to do that, whether or not it's patching it with a piece of vein of the patient. You can use that. You can take the vein as a graft and use that to replace the hole in the artery and or repair it just with sutures alone, put some stitches in it, and that should be enough to control
Starting point is 00:21:38 it. So as long as you can get control above and below the injury, most things can be fixed. And then does blood find its way around other places? Is it like a detour on the highway? While you have it clamped down? Yeah. Yes, it can depending on where the injury is. So for example, in the leg, commonly people get shot in the leg in trauma situations and
Starting point is 00:22:00 it happens to be in an artery in the thigh, which is a femoral artery. You can repair that. There's another deep femoral artery that they can get blood supply around it, but you are having some time of ischemia. There is some time you're not getting any blood flow, which is why the repair has to be somewhat expeditious because after, you know, in the leg,
Starting point is 00:22:17 it can probably tolerate at least four or five hours, maybe, of ischemia before you start to get now death and muscle death and tissue death. So that has to be taken into consideration for sure. And ischemia is the term for not getting enough arterial blood because you've been shot in the leg in the femoral artery and thus not getting enough oxygen to those parts, which can lead to very unhappy tissues and muscles.
Starting point is 00:22:48 When you're doing surgery and they say, oh, we've got to get up to say a valve in the heart. We're just going to pop into the femoral artery in your crotch. I'm like, how do you get that far? There's got to be twists and turns, right? How do you do it? How? Well, thankfully, at least the first person who designed was the Selinger technique of
Starting point is 00:23:07 putting a needle and a wire and a catheter into a vessel. That principle has been taken to make larger and bigger sheets and catheters, just devices basically that can transfer catheters and balloons and even valves directly into the heart. So it's a straight shot because like I said, it's a pipe like any other pipe. And you can go through the pipe with any sort of tool as long as it's a decent size. And there's not a lot of clot or anything
Starting point is 00:23:38 that would be obstructing. That's medical advancement. It's been probably one of the most remarkable things that we've done in the last 60 years or so is being able to do a lot of things minimally invasively because there's a direct route. So that's great. The anatomy is pretty consistent and well described. So Swedish radiologist Sven Ivar Seldinger debuted this technique in 1953, which uses a hollow needle to get under the skin in which you can insert a thin wire as a guide through your blood plumbing, which then guides a catheter
Starting point is 00:24:11 to quote, previously unreachable vascular areas of the body. And then you withdraw the guide wire. What a revolution, right? But no, he wasn't carried on people's shoulders through the town square. No one threw confetti at him or gave him candy or named a day in his honor. It wasn't until 30 years later that the field of angiography, which is mapping the circulatory system, gave him the credit that he deserved. But still worth doing, even if it seems like people don't notice while you're alive. But whatever your hobby or your passion, it
Starting point is 00:24:41 doesn't have to involve vascular surgery, even though it's pretty tight. It's so bonkers that that can even happen. And when it comes to history and your history, how did of all of the winding, twisting roads one could take, how did you end up in this field? I chose vascular surgery, and it takes a while to become a vascular surgeon in terms of the route from medical school to surgery training at the time
Starting point is 00:25:06 So the thing is I'm getting older now. There wasn't a direct route from medical school direct to vascular surgery So I actually did general surgery first which is operating on every part of the body and Then I while I was doing that I had to make a decision about which specialty I was going to do within surgery So I think that part of my decision was based on the fact that asking for surgery is very delicate. We deal with very, also sick patients and the actual procedures themselves require sort of a very gentle hand, which I think I have and I enjoy that delicacy of operating.
Starting point is 00:25:43 And also we have a lot of variety as well. So like I said, one day I'll be doing veins, one day I'll be doing arteries, and then I operate on various parts of the body, in the neck, in the leg, in the chest, in the abdomen. So there's a lot of places where you have to be sort of facile with what's there and how to get to some areas,
Starting point is 00:26:02 because arteries and veins aren't just sitting waiting for you, you gotta find them. And so that's always been very interesting to me. And I just love that kind of surgery. So that's how I ended up picking this specific specialty of all the specialties. And like I mentioned before, blood is a very nice looking fluid. The other ones I don't have a lot of affinity for. so I was happy to pick vascular. Does blood look different when it's leaving the heart versus when it's on its return trip? Absolutely. Yeah, when it leaves the heart, now it's been freshly oxygenated, so it's nice and bright
Starting point is 00:26:36 red. So arterial blood looks really red, like scarlet. And then venous blood, when it's returning, it's much darker because now it's, quote unquote, deoxygenated. There's not a lot of oxygen in it anymore. And when it's returning, it's much darker because now it's, quote-unquote, deoxygenated. There's not a lot of oxygen in it anymore. And so it's darker, kind of violaceous, like a color that we can describe it. So arterial oxygen-rich blood is bright red.
Starting point is 00:26:56 And Venus blood is a little more purplish. Arterial is the color of bright ketchup. And Venus blood looks a little more like a plum sauce or the color of raspberry jam. I'm trying to make this appetizing. So you can tell if you puncture a vein or puncture an artery sort of immediately in a healthy person you can tell whether you're in an artery or vein just by the quality of the blood you're looking at. What about when we look at veins and they look blue from... They should. Yeah, they should look blue. Why are they looking blue?
Starting point is 00:27:28 Because the blood is dark now. So they should look blue in a healthy vein. That's its right color. Yeah, I remember hearing myths about that. Your blood is blue until it hits air. I think they're probably referring to the oxygenation situation and the arteries being more red blood because it is oxygenated blood. I mean I heard all kinds of stuff when I was a kid.
Starting point is 00:27:49 I mean I think we thought unicorns were real. What happens when you blush or when you're embarrassed or when you get hives? Is that blood just flooding capillaries? Yeah capillaries and very small arteries and veins in the face, really, and they just dilate. So it's a parasympathetic response and a sympathetic response, and you get huge vasodilation and then it bursts and then it goes away. So it's kind of like a big flash. It's mysterious really why it's so specific to certain areas that
Starting point is 00:28:25 we still don't understand. I did find a 2020 paper titled the unique contribution of blushing to the development of social anxiety disorder symptoms results from a longitudinal study. The methodology of which involved making kids perform a song in front of a parent and a stranger and then watching themselves back on video before a researcher aimed an infrared temperature gauge at their cheeks to determine if they would be prone to later developing what's known as SAD, social anxiety disorder. Why blushing happens?
Starting point is 00:28:56 I don't know, but what's valuable about this study is that it will be cited often in those kids' future therapy appointments. Someone's making money off that. Do you ever think about that stuff? Are you aware of your own blood day to day? No, thank God. I don't really think about it that much, quite frankly, at least on my own day to day.
Starting point is 00:29:18 What I do think about is venous health in a way, not necessarily the blood itself, but for example, like I wear compression stockings at work because I don't want to have swollen feet, et cetera, because it's more common in jobs where you're standing all the time. The second I knew about that in residency, I started wearing them like right away.
Starting point is 00:29:37 I was like, this is important. And I feel like more people should know that if they're in jobs where they stand all the time, or when you get pregnant, you should wear compression stockings as much as you can. Yeah. What about on airplanes? Absolutely. Yeah. What's going on with that? So the gravity, which is sitting down with your legs that way, and then the pressure changes in the air are more likely to make blood pool at the ankle and you get swollen, especially for long flights. It's a game changer.
Starting point is 00:30:05 So I tell everybody who listened to me to wear them on the plane all the time. No, but I think that's caught on. I feel like a lot of people are doing that. Now, you know, I have a friend who's a doctor who's also at NYU, Mike Natter, who got me a pair of compression socks and I should have packed it for my flight. But what about varicose veins? You said that you work on that. How do those happen? And are we treating them we, as if I helped, treating them with lasers more?
Starting point is 00:30:32 Do you have to go in there and pluck them out? So I think that's another part in which we've had a lot of advancements over the last 30 years. So varicose veins, and you'll hear a lot of terms used to describe it, like venous insufficiency, venous incompetence, varicose veins and you'll hear a lot of terms used to describe it like venous insufficiency, venous incompetence, varicose veins, but ultimately what it means is that one part of the venous system is not doing its job correctly. This is all in the lower extremity for the most part. So in the lower extremity you have two systems of veins, two main ones. You have the deep veins which live
Starting point is 00:31:04 in the muscle. That's why we call deep veins, which live in the muscle. That's why we call them deep, because they're in the muscle layer. And those are the most important veins. They do about 90 plus percent of the work of getting the blood from your foot back up to your heart. They also have a secondary system of veins, which is a superficial vein.
Starting point is 00:31:21 So, the reason they're called superficial is because they're above the muscular layer and they're just surrounded by our skin and fat. But it's connected to the deep system. We call the connections between them sort of perforators and together they're just supposed to transfer the blood from your foot back up to your heart. What happens to a lot of people over time,
Starting point is 00:31:42 about probably 20 million people in this country suffer from this, the superficial system becomes incompetent. And what that means is the valves in the inside of the superficial veins, they stop closing tight. So these are the gates that I described that open shut to let the blood go up. They become incompetent, become weak so they don't close as much as supposed to. And so blood takes longer to get out of that superficial vein. So what happens if there are venous blood traffic jams because the gates and the valves went wonky and they can't merge from the superficial veins to the deeper ones and then back to
Starting point is 00:32:17 the heart for more oxygen? What happens? Over time your body's way of dealing with sort of, we call it this venous hypertension in the leg is to make varicose veins. So you'll see these large sort of bulging little varicosities that come out of there. They're not supposed to be there. Your body made them to deal with the pressure in the system. And so that's a sign that you have quote unquote venous disease, right? And the treatment pretty much for thousands of years is you get rid of it somehow.
Starting point is 00:32:45 Olden times they used to have to strip it, right, which is basically make incisions in the groin and lower leg, and then remove the vein entirely. And that would be it. What's my other option? And then now, thankfully, we have lasers, which is what you were describing before, which essentially do the same thing, but they do it through a catheter, again, like I told you, needle wire catheter through there, and then seals the vein from the inside, which essentially shuts it down. So the technology is a lot better now,
Starting point is 00:33:13 and that's kind of like an outpatient in the office procedure. Takes half an hour, patient's too well. We check on them probably a week later, and they can return back to work the next day. So it's very ambulatory and their legs improve pretty remarkably quite quickly. So it's very rewarding. This is the part I was talking about.
Starting point is 00:33:34 In terms of lifestyle, they're able to walk further, do whatever they need to do, less likely to get wounds in the future. But their data about that is still soft because we don't really follow them for 40 years to see what they're going gonna look like, unfortunately, but that's something that I think intuitively makes sense. Are varicose veins just a cosmetic concern? Are those a concern in terms of your actual vein health that if you're making extra veins,
Starting point is 00:33:58 you've got some issues down there we should solve anyway? Yeah, so I think there's two camps about that. There's certain patients who will start off with just varicose veins and may just stay like that for the next 40 years, okay? They'll have probably some like swelling, some heaviness, fatigue, and they can tolerate that. There's some patients who will start off
Starting point is 00:34:17 with varicose veins and they'll end up, and I'll see them in their 60s and say, you know, they started when I was 30, and they told me it was just cosmetic, and now they have horrible wounds and all sorts of problems. And so question is, had we started to treat them in their 30s, would they have been this miserable in their 60s?
Starting point is 00:34:34 And I think that I fall into that second camp of trying to make sure that their veins are as healthy as they can be throughout their lifetime. So it's really a conversation with the person that you're treating about what it is that they're trying to accomplish, what their life goals are, what their functional status is, what they want to be able to do.
Starting point is 00:34:51 And that becomes more important to me than the other parts of it. Do compression socks help your veins with that too? So I think having compression is an assistive device, right? Because it creates a higher pressure at the ankle so that the blood doesn't pull there So even if you do have vein problems that will help at least boost some of the flow out of the leg So yes, I think that they're important. I wear them like I told you even though I don't have these Because I just want to make sure that they're as healthy as they can be. Yeah, what about crossing your legs?
Starting point is 00:35:23 just want to make sure that they're as healthy as they can be. What about crossing your legs? Not bad, actually. It's bad for your hips, and apparently I have to stop doing that. I do it all the time. I'm doing it right now. And the compressing blood flow, no. What that will do is mostly muscular and then nerve. It can pinch your nerve in your property or fossa,
Starting point is 00:35:40 and that can cause, you know, when you've crossed for too long, and you feel like your foot's numb and you can't feel it, that kind of thing. But not the blood flow will still be fine. So your footfall asleep is not usually a blood issue, but it's a neurological one, the nerve. And you mentioned deep veins, deep vein thrombosis. Yeah. I feel terrified of it.
Starting point is 00:36:00 I have a friend who went through it recently as well, and luckily she's on the men, but has to be on blood thinners. So when we hear about blood clots versus deep vein thrombosis, what's going on in there? Yeah, deep vein thrombosis is the part of venous disease that can be life threatening, because a not insignificant number of people, around 600,000 people die a year from a deep vein
Starting point is 00:36:21 thrombosis, and the reason they die isn't from the clot itself, it's from the clot traveling to their heart because, like I said, it's connected. And then once it goes into the heart and then into the lung arteries, it's called a pulmonary embolus. And that can kill you because if their heart has obstructed flow and it can't get blood out, you get a heart attack and then they die, and it's a cause of sudden death. And heads up, so DVT, or deep vein thrombosis, happens when a blood clot, or a delightfully named thrombus,
Starting point is 00:36:53 forms in the deeper veins, and usually a leg, like at the side of those valves or gates, and symptoms can include swelling, pain, fluid retention, some discoloration, and even fever. Now, if you have DVT, a doctor may put you on blood thinners to prevent that clot from detaching and just going on a walkabout to places you don't want it, like the lungs or the heart or your brain.
Starting point is 00:37:18 As for COVID and clotting, a 2023 study, risk of thrombosis during and after SARS-CoV-2 infection, pathogenesis diagnostic approach and management in the journal Hematology Reports says that coronavirus disease COVID-19 increases the risk of thromboembolitic events, especially in patients with severe infections requiring intensive care and cardiorespiratory support, and that COVID-19 patients with thromboembolitic complications have a higher risk of death. And if they survive, these complications are expected to negatively affect these patients' quality of life.
Starting point is 00:37:54 So COVID increases the risk of blood clots, and the worse your case of it, the more at risk you are for that. It also says that recent data show that the risk of thromboembolism remains high months after the infection. Now, why is this happening? And there was another study, a 2023 study, SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels in the journal Nature. And it presented data that established that SARS-CoV-2 infects coronary vessels, inducing plaque inflammation that could trigger acute cardiovascular complications
Starting point is 00:38:29 and increase the long-term cardiovascular risk. So COVID ups your chance of clots, and data show that it can infect coronary vessels. So how do you not get blood clots and thrombosis? It's never a bad idea to avoid getting COVID. Remember to get your boosters. Don't be afraid to mask up because a blood clot is scarier than a weird look from a stranger, in my opinion and experience. But other ways in
Starting point is 00:38:53 general to prevent blood clots and deep vein thrombosis are to keep it moving, move your body if you have the option. So I think it's important for people to know about it. And the ways to prevent it really are minimal. A lot of it can happen in a hospitalized setting where you're immobilized for a long time or you've had orthopedic surgery, et cetera. This is where compression becomes important.
Starting point is 00:39:19 Moving is important. Also, if you have had a surgery or you have a family history of blood clots, then you may need to be on blood thinners to prevent that from happening. But it is something that is a serious problem, right, and can happen in an unrecognized fashion. It's still rare, we'll say that, like most people aren't going to have it. Like I said, 20 million people have superficial brain disease, but not a lot of people get DVTs in general. But that's something that should be recognized more, I think, in general and in public health, because the people who tend to do worse from it
Starting point is 00:39:56 tend to be minorities, underrepresented minorities specifically, especially after childbirth and women. That's something that we've seen. I think even Serena Williams had one and had a second one, I think, at her second pregnancy and that wasn't recognized, but she knew what was happening and she had to tell the doctors,
Starting point is 00:40:13 this happened to me last time. So that's how, when they recognized it and treated her appropriately. So it is something that should be announced widely and people should be concerned about. What do you look for? Dr. Bloomberg explains. Typically it will start with some swelling and pain in the leg and it's usually not both legs. It's usually just one leg that's asymmetrically for some reason feels swollen, it's more painful, they should get checked out. It's a very simple test to look for it. It's an
Starting point is 00:40:42 ultrasound that's cheap, effective, and highly diagnostic for that, if you get it. Do you find that, especially with people who are going through childbirth, or is it a fact of certain people just not being listened to, or more predisposed, or I imagine a combination of both? I think a combination of both. There are people who are hypercoagulable, right? That's what we call them. They're blood clots for some reason.
Starting point is 00:41:09 Pregnancy by itself is a hypercoagulable state. So women who are pregnant can form more clots because that's kind of the coagulation pathway of carrying a child. So there's a heightened risk and assessment in those patients, and OB-GYNs, I think, are very cognizant of that and do a good job of that.
Starting point is 00:41:28 I think in our medical community, there are people whose pain and or concerns aren't addressed as they should be. And I think that's hopefully changing, especially as the workforce that takes care of them changes, right? So if you're more aware that this happens to minorities and there are some minority doctors that helps
Starting point is 00:41:50 to move that forward. And so I think that's improving, but it has been an issue historically. When it comes to getting the word out about venous health too and arterial health, what are things that you wish people knew before something becomes a problem? Yeah, so I think we'll start with arterial disease first. I'll say simply smoking is bad.
Starting point is 00:42:15 It's always been bad. It's going to continue to be bad. And I don't think, and I know that now in New York state has ads about people losing their fingers and their toes, too, and there's quit smoking campaigns. And that's important because they've previously never addressed the fact that that's actually a risk factor of smoking is that. So I think that's the one thing. You can just not start smoking because it's extremely hard to quit. And we talk to patients about this all the time. Don't do that. The second thing is diabetes. That's still today now is the number one cause of amputations in this country after trauma.
Starting point is 00:42:51 So if you're not in an accident where you lose your leg, diabetes is the number one cause of you losing your limb in this country. And that's a big problem. So diabetes control, which also stems now from obesity. So we've mentioned this in previous episodes as recently as last week, but some people object to the word obesity to refer to certain body compositions that could potentially impact health negatively. But it is the current medical terminology that doctors use.
Starting point is 00:43:19 And while some doctors have overlooked actual causation of illnesses by wrongfully blaming body composition. Most like Dr. Bloomberg are relying on years of research to keep us all living longer and healthier with fewer complications. So it all starts there. So this is the thing. So health and wellness, I'm sort of an end stage doctor. By the time you get to me, a lot of things have happened along the way that hopefully could have been reversed. So I think weight control, obesity management, diabetes management, smoking, those are sort of the pillars of
Starting point is 00:43:53 arterial health and also venous health because we'll now switch to veins. Remember, veins return blood to your valentine heart. Function of veins is dependent on returning flow from a foot up toine heart. Function of veins is dependent on returning flow from a foot up to the heart. Weight plays a big role in that. If you're overweight, that's just a harder job for your veins to do. And that contributes to the development of the disease
Starting point is 00:44:17 and also the outcomes after you start treating the disease. It's not just lasering everything, right? And those are the things I wish people knew beforehand. And then also wearing compression socks, if you stand for too long at any job, because I see a lot of people, mostly women, who did factory jobs, machinists, nurses, doctors. And they're all like, yeah, my legs have been killing me for years. And I think we used to have a fair once a year at NYU, where we would just give out compression socks and you could sign scripts for people,
Starting point is 00:44:44 just so that the workforce could have it because we knew that this is the thing. So that's important, I think. You mentioned smoking too. And I have been in New York for just this past week and I'm from California and I have walked through absolute fogs of weed. And I feel like more people smoke not just cigarettes, but just in general, people who don't smoke cigarettes or maybe smoking more weed and vaping. Do those have any impact on your venous health? You ready for this? Yeah, I think the data on vaping is that it's pretty much as bad as tobacco.
Starting point is 00:45:18 And also the particulates in vaping may actually be worse, at least for lungs in general. But that's a different ballgame altogether. The marijuana smoke and the legalization of marijuana has actually opened up a huge can of worms, I think, for people regarding public health because you'll have conversations where people think it's natural. Me and Mother Nature. And therefore it's not going to harm them, but we don't have enough data on long-term use of marijuana
Starting point is 00:45:49 and how that affects the arterial system. I can say our suspicions from the early reports now are that it's quite damaging to your circulatory system. And unfortunately with the widespread use, I think we're gonna start seeing that in younger people who are consuming it at these high rates. And that's a big concern to me because I think this concept of it's a plant and if I smoke it, it's not tobacco.
Starting point is 00:46:21 So it's not gonna hurt me is a problem. There's other things that are natural that occur in a plant. Well, it's just heroin comes from a flower. It's not necessarily good for you. Now that it's legal, it can actually be studied, right? And the natural population, natural studies will start to come out. And I'm not optimistic that it's going to be good news. Stick to gummies, maybe. Yeah, if you need it, yeah. Okay, smoking weed, definitely not without its bodily consequences
Starting point is 00:46:49 from a vascular biology standpoint, sorry to say. And for more on this, you can see the 2019 paper, Harmful Effects of Smoking Cannabis, a Cerebrovascular and Neurological Perspective. And also news came out in 2022 that if you're an adult who has a bleeding stroke and you have enjoyed the ganja in the last month, you're twice as likely to die or have serious injury from that stroke. But it's really hard to determine what's caused by the smoking or the vaping factor, right?
Starting point is 00:47:17 So I did this deep dive on edibles and you don't want to hear this. Neither do I. But I have a responsibility to tell us that a 2019 Annals of Internal Medicine paper, acute illness associated with cannabis use by route of exposure did find that according to the Colorado Behavioral Risk Factor Surveillance System, about half of THC users just smoke and about 4% just do edibles and the rest are kind of a combo of both. But edible cannabis did account for more ER visits for acute psychiatric symptoms. So don't let your mom eat the whole brownie. And visits for cardiovascular symptoms.
Starting point is 00:47:55 So that's concerning. Does it have to do with all the snacks you like to eat when you're cooked? Jury's still very much out, and more research needs to be done, and doctors and scientists still need more questions answered as do you Can I ask you a couple questions from listeners? Do we is your heart out nine just checking? No, okay Okay, sweet. So let's lob your questions to her about bruises cold feet Why you should get an ottoman how to make a phlebotomist's day, barbers gossip about royal families and much more. But first let's toss the money down the pipes to a good cause and this week Dr.
Starting point is 00:48:29 Bloomberg selected breaking ground which enables people to forever escape the trauma of homelessness and their wraparound services include benefits assistance, primary medical care, mental health care, substance use referrals and skills building to help each person get and stay on the path to permanent security. And each year, Breaking Ground serves more than 10,000 vulnerable New Yorkers. And to find out more about Breaking Ground, head to breakingground.org.
Starting point is 00:48:55 And that donation in honor of Dr. Sheila Bloomberg was made possible by sponsors of the show. Okay, let's tap it. Let's let these queries flow. You can submit your question before we record at patreon.com slash ologies and it costs just a buck a month to join. This first topic was a curiosity of patrons Sheepin, Perry Wilson, who just got their first old lady bruise, the very clumsy Atticus Atlas, Etta Rose, first timer Madeline Ash, Keyline
Starting point is 00:49:19 Pie, Clark Bennett, Mouse Packs, Vanessa Adams, Mark Rubin, Anna Dillon, Olivia, Anna Thompson, Barb Miller, Greg Lewis, Audrey Hudak, and Valbie Liston. Yeah. A lot of them. Want to know, Audrey Hudak asked bruises. What are they exactly? Why do some people, in Sheepan's words, why do I bruise so badly? Is it because I'm vampirically pale?
Starting point is 00:49:39 Perry Wilson said I just got my first old lady bruise with broken capillaries. What is happening with bruising? So bruising is at the very superficial level of the skin where the, I guess we can say capillaries slash veins burst just from injury, right? So it's very localized. You're obviously going to see it more if you're pale. Some people are more prone to bruising because they have either some platelet dysfunction where they don't clot fast enough. Because if they're able to clot fast enough, it shouldn't bruise as much or shouldn't have as much spread of blood in that area. And so people who are prone to easy bruising, they should just have a
Starting point is 00:50:17 simple blood test just to make sure they don't have an issue with clotting disorder or bleeding disorder. Other factors that can cause easy bruising are taking medications like ibuprofen or Advil, naproxen like Aleve, blood thinners, antidepressants, and antibiotics. Now another cause of easy bruising is not having died yet. And as we continue to age, our skin gets thinner and has less cushion for that blood tube in we've got. And I asked the Mayo Clinic how not to have purple legs and it offered the following solutions. Use good lighting in your
Starting point is 00:50:51 home. Have your vision tested. Arrange furniture and electrical cords so that they're not in your way when you walk. Avoid clutter. So doctors say lovingly either check your meds or get your shit together. I was getting a ton of bruises and then I realized it was because I was eating too many baby aspirin. I'd get a headache and be like, ooh, baby aspirin's delicious. And then I was like, you're chilling. I'll have one more. Yeah.
Starting point is 00:51:13 And then I thought I had leukemia. It turned out I was just eating too many. What about circulation? So many people wanted to know why are my hands and feet so cold? Diana Burgess-Roslyn has been at Renderb Bosch, Anastasia Press, Mary Anne, Sienna, Rick T., Kyla Fret, Jackie G. Is it poor circulation or is that just a myth, Dr. Casey S.? So the cold hands, cold feet.
Starting point is 00:51:33 There's some people who have perfect circulation and have cold hands and cold feet and they'll come in and there's not much we can do for them because there's no blockages, right? There are some people who have a phenomenon called renoids where essentially they spasm. They're very, very tiny arteries in their hands and especially gets worse in the winter time. What we recommend is just warming for those kinds of people because it's usually related to underlying
Starting point is 00:52:00 rheumatologic problems that they may also have. So with renoids, your blood vessels may kind of slam shut. And my friend Mackenzie has this. And a few of her fingers can just suddenly turn white. I think it looks cool. But as an equestrian who's outside a lot, she's got to keep those fingers warm. But if you start to notice that you're just developing
Starting point is 00:52:18 cold hands or feet and you haven't just moved to Canada, it could indicate a new issue, like peripheral artery disease, which is when plaques form in the arteries of your limbs, or something like an autoimmune disease like lupus or rheumatoid arthritis or maybe a thyroid issue. And yes, we do have an episode on thyroid coming up. Also in terms of chickening out on something, the origin of the phrase cold feet is hotly debated. But in 2005, Slate published the article, When Did We Get Cold Feet? The Germans Had Them First, which is accusatory, Slate published the article, When did we get cold feet? The Germans had them first, which is accusatory, but it traces the popularization back to German
Starting point is 00:52:50 soldiers apprehensions in getting killed in World War I. They were like, I can't get out of this trench. My feet are too cold. But centuries earlier, an Italian proverb involved being cold in the feet to mean being shoeless, to mean being broke, which then meant that a gambler was too belly up. So they backed out of a bet, which if you're broke, backing out sounds like a great idea, like 10 out of 10 would bail ASAP. But if your actual feet and hands and nose are cold and it's been like this for a while,
Starting point is 00:53:20 that's kind of your brand. Docs say that it's healthy for your body to say, hey, I'm cold, I'm just gonna hoard more blood in our organs, if that's cool. Because you can't put a beanie on your liver, babies. It's very, very rarely a limb threatening or a digit threatening problem. But there are some people who just have peripherally cold hands and cold feet, and my daughter is one of them.
Starting point is 00:53:42 There's nothing to do about it. So it's- She's not's nothing to do about it. So it's. She's not like, mom, fix it. Yeah, yeah. It was like freezing hands since the day she was born. And there's nothing to do about it. So pockets. Yeah.
Starting point is 00:53:55 A few people, Bjorn Fredberg, Miranda Panda, Sadie Vipond, wanted to ask about hemophilia. What is it, what is it in Bjorn's words that hinders the blood from clotting or lack thereof? Yeah, that's taking me back to sort of med school. That's more in the hematologic sort of realm as opposed to circulation. And it's genetically inherited. At least the most famous one is from mothers to sons because it's on the X chromosome.
Starting point is 00:54:23 So it tends to be more profound in boys because at least girls have two Xs, whereas boy has one X and one Y. So if they tend to present in boys because they're the ones who'll manifest it, whereas the girls will have protection from the second X. And those are the ones who can't make that factor and then they bleed.
Starting point is 00:54:43 And I think one of the czar's sons had it, Nicholas, back in the Russian Revolution. And he was basically contained in a bubble as long as he can until the revolution. And they killed his whole family and his well. But yeah, and that was passed from, I think the Tsarina's line of families. But yeah, so it's a coagulation pathway problem where one of the
Starting point is 00:55:06 factors is missing. And those are still quite rare in hemophiliacs. Okay, so this side quest of info dumping kind of warrants its own three-part episode. So I'm just going to give you some broad strokes, if you will, and move on. So there was this mysterious blood and bleeding disease among European royal families, and it all traced back to a blood disorder transmitted to various European royals by Queen Victoria, who also went by the title Her Majesty Victoria by the grace of God of the United Kingdom of Great Britain and Ireland, Queen Defender of the Faith, Empress of India.
Starting point is 00:55:38 And yes, one of her descendants among royals was Alexei, the great-grandson of Queen Victoria, and he was a chunk of a baby, 11 pounds of butterball baby, but he had this royal disease. It was found out when his umbilical cord bled for hours and hours. His royal family was freaked out, but they didn't disclose his health problems to the public. Now, over the course of his childhood, he nearly bled out, externally or internally, from events as slight as a bump to the leg or a nosebleed. And there was this peasant monk who came along named Rasputin, and he was said to have the powers to cure Alexei by just pushing aside doctors' care and healing him through hypnosis and spells and just Riz in general. But medical historians are now like, it may have just helped that he told the doctors to stop giving him aspirin because the aspirin thinned his blood. Also, placebos, they don't not work. Science knows that. But sadly, Alexei's
Starting point is 00:56:33 fate was sealed by execution in a cellar at age 13 during the February Revolution in 1917. Now, the family's remains were discovered 90 years later, and finally in 2009, the paper Genotype Analysis Identifies the Cause of the Royal Disease revealed that the royal disease was hemophilia B, a blood clotting disorder which can be carried by females but can manifest in male descendants, or it can just arise spontaneously in a family line, especially by mutations resulting from older dads spermies. But speaking of history and shady medical treatments, I do want to let you know that yes, bloodletting was a thing up until like the 1700s. And back in the day, barbers,
Starting point is 00:57:17 they were the only ones with sharp tools in town. So they were tasked with all kinds of things like opening veins up and extracting teeth, applying leeches and setting bone fractures. They were the original med spas. Barbershop surgeons also cut hair and stuff. And that striped barber pole that you see outside modern day establishments. So legend has it that it descended from the shape of a basin of leeches at the top and the stick that patients would
Starting point is 00:57:47 grip to encourage little suckers to do their business faster. Now, others say that the red stripes are reminiscent of stained bloody strips of gauze. They would hang outside to dry. Either way, next time you have any medical procedure done, be glad that you're not surrounded by stray beard hairs and a weirdo with a leech and that you have a nice person in a clean lab
Starting point is 00:58:10 coat in front of you. When it comes to drawing blood, yeah, people asked, Bulky Kipple says, when I'm getting blood drawn I'm always told I have good veins. What does that actually mean? Bart Miller asked, why do phlebotomists always have a hard time finding my veins? When it comes to bloodletting, why some people don't do as well as others? Well, we're hopefully we're not bloodletting anybody anymore. Drawing blood, if you have good veins, it basically means that you've made everyone's job easier because you're plump veins and hydrate. And there's some, when you put the tourniquet up in order to see the veins, when they're drawing blood, some people become more prominent than others. Depends on the state of hydration. Sometimes
Starting point is 00:58:54 they dehydrate, et cetera, and their veins are not visible or you can't touch them. You can't feel them when you touch them. That makes it more challenging. So people who have more prominent veins, who may have, you know, probably thinner arms, etc., may be easier for us to get blood from. There's some people who for whatever reason, and this is usually most difficult in hospitalised patients who've had multiple blood draws or who need blood repeatedly, at some point the veins been touched and injured too many times that it can't be accessed we call them quote-unquote tough sticks like you can't find a good vein in there, right and Most of those people you want to try to find places where the skin is kind of the thinnest
Starting point is 00:59:37 so that's why a lot of people end up getting blood drawn in the Not armpit, but here in the elbow pit the not armpit but here in the elbow pit, the antecubital fossa is what we call it, because it's probably the thinnest place where the veins come up to the skin at a level which most people can access. So you could make a phlebotomist stay by hydrating a little. Yeah, if you're able to, because sometimes they make you either fast for a blood test or something like that, depending on what it is, but ideally chug a bunch of water beforehand. If you know you're a tough stick, I will help. I just love the idea behind the scenes someone's saying, oh yeah, room 14 is tough stick, man.
Starting point is 01:00:13 Tough stick. What about rolling veins? A ton of people asked about, Gabriel Heiss asked, which said fantastic about the topic, excited about the topic. Why are some veins rollier? fantastic about the topic, excited about the topic. Why are some veins rollier? I've never heard the term rolly veins. Also on the minds of Kay Lucas, Gabrielle Heiss, Deth Nell Kieran, Nehemiah Miles, Miranda Panda, and first time question asker Bethany Scholes, who has rolly veins, and after seeing them
Starting point is 01:00:39 via a nurse using a laser vein finder, asked, why hasn't the goth clothing industry capitalized on vein pattern arm sleep? Asking as a goth scientist, Bethany says. Bethany, you're living in the future, but you still have rolly veins. What's up with that? I think that's more common in a way in very thin people
Starting point is 01:00:58 because if you have less fat surrounding the vein, when you try to come after it, it just moves along the skin and you'll see it and it's like, oh gosh. So you have to kind of stabilize it a little bit as you're trying to access it. You got to chase them kind of going side to side. You have to kind of anticipate where it's going to go next and find it there. That's how I do it when the veins are rolling. Sean Thomas Kane and
Starting point is 01:01:25 RP Bergman wanted to know in Sean's words, is there a scientifically proven best practice for stopping nosebleeds? Is that a vein? Is that an artery? I mean everything at some point is in her artery but if you're having a nose bleed periodically, I mean it's now head down and compress it, even with like a tampon actually in the nose and just let it hold pressure and it'll stop. But don't do this, don't put the head back. You don't want to swallow the blood into your mouth.
Starting point is 01:01:54 So head down. So head down. And put some tampons in it, in one nostril. Or if not, a cotton ball, something that you can actually pull out easily. You don't want to get anything stuck there either. Head down. That's new information to me.
Starting point is 01:02:07 Non-menstruating people, keep a tampon in the glove box. You never know who, you never know what hole might need it. Now this one was on the minds and in the bodies of Patron Storm, Addie Capello, First Timer, Jasmine Tsai, and Marine Flood, which is a great name for a blood episode. Collapsed veins. People have asked when they've donated blood, a vein collapsed.
Starting point is 01:02:28 Is that, does that have to do with the musculature? I think when they tell you your vein has collapsed, it basically, for whatever reason, at the point at which they've drawn blood, it's just kind of spasmed. Okay? So that's usually temporary. So don't freak out if your vein collapses. No. It's still there. If someone tells me a vein collapsed, that's terrifying. You're like, I need that usually temporary. So don't freak out if your vein collapses. No, it's still there.
Starting point is 01:02:45 If someone tells me a vein collapse, that's terrifying. You're like, I need that. Yeah, it's still there. It'll be back. It just needs a break. It's had enough. Just give me a minute. Carlos de la Rosa and the Severinos asked about chemotherapy and vascular health. Is there a way to recover or heal the veins from the back of your hands or anything during chemotherapy that
Starting point is 01:03:05 you would recommend? So chemotherapy is tough because it really does destroy the cells within the lining of the veins just because of the nature of the drugs that are going through, which is why they prefer to put it sort of directly through a port as opposed to peripherally, although sometimes now they are using the veins in the arms directly for chemotherapy. Unfortunately, we don't have good reversal for that once that happens to it or protection for that. Where does the port go?
Starting point is 01:03:35 It goes in the, depending on where the, either the subclavian vein, which is up here by the clavicle or in the neck IJ, the internal jugular vein, and then the port sits at the chest level here because it's a clean area less likely to get infected and they can then access it repeatedly, especially if you need multiple rounds. It's supposed to try and access the vein multiple times in the hand. Like we said, it can collapse, it can spasm, and then just tolerating the toxic chemicals, it's kind of easier because here's a direct shot into the heart. So they get the medication sort of straight centrally and then that gets distributed throughout the body.
Starting point is 01:04:14 And you mentioned the jugular vein, which is the scariest sounding vein in the body, just because it's like going for the jugular. Yeah. Why is that jugular so important? I think the jugular vein has sort of been mythologized as like the one that will murder you if somebody cuts you. But I think what people forget is what was causing death wasn't the jugular vein, it was the carotid artery that was next to it. So when, for example, in Quentin Tarantino, when they cut somebody's neck and all that blood and everyone's like, oh, it's the jugularular vein that's the carotid artery that's been injured. So the
Starting point is 01:04:47 jugular vein is famous but it's not really earned its place in our mythology but I think it's mostly carotid injuries are the ones that are the life-threatening scary things as opposed to the jugular vein. So we've been lied to and in case if it ever comes up over dinner, maybe with extended family, someone mentions a stent, no one else knows what that is, you now are about to know that stents are these little mesh tubes that vascular surgeons might use to open up a blocked or collapsed vein. And they can be made out of metal or biodegradable materials, they can have
Starting point is 01:05:23 medication embedded in them, although the metal stents can become overgrown with scar tissue, which is why there are some newer options. So I hope that answers some stent questions, Brooke Dombroski, Amber McIntyre, and Mark Hewlett. Now, patron Rebecca Fitchett issued a command, a polite command, please talk about aneurysms. And that was echoed by Kelly Shaver and Stephanie McKetchney. And the quick FYI is that an aneurysm, it means dilation in Greek, and it's when a blood vessel, like a vein or an artery, weakens or bulges outward,
Starting point is 01:05:55 like a little balloon. And that can cause symptoms, especially neurological ones, if it presses on structures in the brain, and can even lead to strokes or insufficient blood supply to parts of the body. So managing high blood pressure can prevent aneurysms because then the pressure inside the veins is lower and it pushes outward less. And Stephanie, I hope your dad's okay. And everyone else, I hope this helps you understand episodes of Grey's Anatomy. Now most of my familiarity with the term
Starting point is 01:06:23 aneurysm is from movies like in the 90s where someone has a house party and they're like well my mom sees this carpet she's gonna have an aneurysm or something and I thought that's kind of insensitive but it turns out that yes a sudden burst of anger or physical strain or untreated high blood pressure or just ongoing stress can cause an aneurysm or an existing one to rupture. So please chill for your own survival. And now other patrons Jackie G, first-timer Sean Kavanaugh, Hayley Kirby and EDM asked about vascular surgery in general. Like what when you're going in there as a
Starting point is 01:07:00 surgeon and you're working on veins and arteries, how are you sewing them up? Is it the tiniest thread you've ever seen or are there glues? What's happening? It's sutures. They're pretty small. We grade them on most sutures in level of zero to like 14 and the 14 being very tiny, tiny, almost less than even a hair quite frankly. But we use microscopes.
Starting point is 01:07:23 So we have loops to magnify what we're doing, but it does need to be a fine suture, which is why I was telling you about the delicacy of it, which is why I like it. Do you do crafts as well? I used to knit a lot when I was younger, and now I don't do anything fun like that. Like enough embroidery at work, I'm sure.
Starting point is 01:07:40 Knitting and crochet were my go-tos when I was younger. Can you not drink coffee before a surgery like that? No, I drink coffee. And your hands don't shake? Yeah. Okay. I'm good. Some people had to stop.
Starting point is 01:07:53 Apparently when I get older, I might have to stop, but for now, it's so good. Steady hands. You mentioned tourniquets earlier. My husband is a big safety nerd and has a tourniquet on him in his fanny pack at all times. Oh my God. He took like a stop the bleed course just in case. Good for him. Go figure.
Starting point is 01:08:09 Yeah. I guess CPR is next. We should both probably know CPR. Yeah. But when tying a tourniquet, what's the protocol? So the tourniquets that are available now have their own. Each can be a little bit different. OK.
Starting point is 01:08:22 But depending on where you're putting it, you're gonna go above the injury, right? So if it's in the calf, you want to go in the thigh. If it's in the lower leg, then you want to go upper in the thigh. And when you place it, you have to try to turn the tourniquet so that it's tight enough that it's occlusive. And the point is, once you see that the bleeding has stopped,
Starting point is 01:08:44 right, that's the perfect point at once you see that the bleeding has stopped, that's the perfect point at which you can stop turning the tourniquet. Because that's usually just a life-saving measure that should be limited time. Because any time the tourniquet's up, you have to start counting down the extremity that you're treating, whether it's the arm or the leg,
Starting point is 01:09:03 is not getting any blood flow. So once it's up, you start the clock on the tourniquet. I think that's the important part people forget, because once you stop the bleeding, it will stop blood flow. And then depending on the situation, I don't want to lay people getting too crazy about it, but you can also elevate the leg
Starting point is 01:09:19 as you're putting the tourniquet on, just to decompress the venous system, and then put it on. Just put it on, turn it till the bleeding stops and then someone's already calling for help. Please call an ambulance. Call an ambulance. Don't just rely on someone with a fanny pack tourniquet, but it's good to have. Yeah, I'm surprised.
Starting point is 01:09:39 I know now that civilians have a lot of things which are pretty amazing. I mean, I suppose he likes to be prepared. Disaster preparedness, yeah. You figure. Okay, on to some more chill stuff. Alex Vangelatos said, I've always wondered if there was a difference between what would be clinically considered varicose veins
Starting point is 01:09:56 and just having very prominent veins, especially in lower legs and feet and hands that really show off, AKA bulge and pulse after exercising Alex says and Alex I found you the article lifting made my veins stick out but here's why I love them anyway in which a fellow vascular biologist and surgical angiologist dr. Jonathan Levison explains that strength training causes the muscles to engorge and swell with plasma, which pushes the veins closer to the surface, making them be like,
Starting point is 01:10:27 hey, especially if you happen to have thinner skin. And whether or not you got a pump today, just kick back a little. Putting your legs up at the end of the day when your feet hurt, good idea? Yes. Good for the veins? Yes.
Starting point is 01:10:39 Yoga, upside down, inversions. Yes, good for you. Take some time, go upside down. Get the blood out of your feet. Yeah, just be in a different position, elevation. I tell a lot of patients who have vein problems, elevate the legs as much as you can. The worst positions you can be in are sitting for too long
Starting point is 01:10:56 and standing for too long. Moving, exercising is great, and then upside down if you can, as much as you can. Or just elevate to whatever degree, you know, if you're as much as you can or just elevate to whatever degree you know if you're older and it's harder I'm not saying to go a standing inversion. Acroyoga? Yeah. The last two questions I always ask what is the hardest part about surgery for you what's the hardest part about your job the most challenging part? The most challenging part is when I can potentially
Starting point is 01:11:28 fix the acute problem, but I know that the patient's not going to make it. For example, this past week had a patient who clawed it. It's like, I can fix that, but if his heart is so damaged, me doing that's not going to change his ultimate outcome. And I think that for me is still the most challenging part. Like, I can do the best thing that I can, but you're still not going to survive
Starting point is 01:11:51 for whatever other reason. So that's still a challenge, and that will always be a challenge with this job. Well, you know, you mentioned that you sometimes see people when they're more advanced in a pathology. Any other advice that you want people to know to take care of that vascular health? Find a vascular specialist.
Starting point is 01:12:13 There's not a lot of us. We're lucky in New York City, there's a lot of everybody. But just speaking around the country, there may not be a lot of people, especially if you're in rural areas, et cetera, who are specialists in this. And this is where telemedicine can be helpful because you can always connect with someone who's not necessarily regionally close but can at least give you advice on how to get
Starting point is 01:12:33 to the help that you need. A lot of patients don't have good access. So please find somebody who's a specialist in vascular care because it's a very subspecialized specialty and when done well can be very helpful. So that's something I wish people knew more of. We're kind of like an underdog specialty. Do we need more of you? We do. We're going to have a shortage in the next probably 10 years of us. But yes, we need more of pretty much most doctors, but yes, definitely we do need more of us. So folks in med school have a rotation in the vascular area.
Starting point is 01:13:12 Amazing. Favorite part about your job, favorite part about surgery? Favorite part about it is always the aftermath. So I think a lot of people who do surgeries, because we do like sort of immediate gratification. And it's very gratifying when you see your patients and they'll come back literally within a week and be like, I feel amazing. Right? And then you're like, okay, great.
Starting point is 01:13:34 Like I did something good and I helped somebody and now they're gonna do great. And if you can help somebody, that's always great. The mood in the OR, because you're doing such delicate work, is it like classical music and hush or do you need energy? Depends on the case, but for the most part, I don't have music anymore. I used to have music in the OR, but then I found that my voice isn't loud enough for
Starting point is 01:13:55 anybody to hear me when I need something. So I stopped with the music and we only get music if I have everything that we need and then we can get music if I have everything that we need and then we can have music. Because the team around me who's not focused, they like the music. And so I try to sort of meet them halfway because I want them to be happy, if they can help me.
Starting point is 01:14:15 And then depending, if it's an emergency, no music. Yeah, focus time. Focus everyone, because everyone's running around and trying to get stuff and we have to just stay focused So emergency is absolutely not regular cases if everything's good. So they whatever they pick. I actually don't pick the music I say whatever they want. Yeah, it's fine with me. Are you the Franklin? Maybe you don't just belt out Aretha Franklin Well, I can't start singing because then I've loose focus I'm trying to hit my notes
Starting point is 01:14:43 It was news to me that they even played music because obviously anytime I've been in an OR, I'm not super present. Right, right. It's like, what, really? We actually take requests from patients sometimes because they want to set the mood for themselves when they come in. Yeah, they should offer you your choice. Spotify playlist.
Starting point is 01:15:00 Yeah. Thank you so much for doing this. This has been such a joy. Again, you've been on my list for so long because there's not a lot of vascular surgeons and you're just at the top of the game. So great. So great. Thank you so much. It was fun. So ask cool surgeons weird questions because now you know about fake blood, karaoke and how to die less. Thank you so, so much to Dr. Sheila Blumberg for letting me meet up with her and thank you to the NYU team for connecting us.
Starting point is 01:15:27 Links to Breaking Ground are in the show notes as well as a link to our website where we have so much info, links to the studies we mentioned, etc. all for you. We are at Ologies on Blue Sky and Instagram. I'm at Allie Ward on both. We also have an Ologist starter pack on Blue Sky, so find us there for sure. Smology's are shorter, kid-friendly episodes you can find anywhere. You get podcasts, and those are linked in the show notes along with merch and a link to support Ologies on Patreon
Starting point is 01:15:55 and submit your questions that I may read on the show. Thank you to Erin Talbert, who admins the Ologies podcast Facebook group. Aveline Malik makes the professional transcripts. Kelly R. Dwyer makes the website. Noelle Dilworth is our scheduling producer. Managing director is Susan Hale, who makes sure everything flows on time. And the heartbeats putting it all together are editors Jake Chafee and lead editor Mercedes Maitland of Maitland Audio. Nick Thorburn wrote the music. And if
Starting point is 01:16:17 you stick around, I'll tell you a secret. And this week it's that we have oak trees in the yard and I harvested a bunch of acorns a few weeks ago and I've had them in this cloudy jar in the fridge trying to cold bleach the bitter tannins out of them and then I got impatient so I tried to do one batch with boiling water and then dry them in the oven but they looked burnt to shit and my almost former spouse, your mother, Jarrett, said that they were not palatable and this broke my heart and I happened to meet up with my lovely friend and foraging ecology guest, everyone loves Alexis Nelson, aka Black Forager on TikTok and Instagram. And she was in town last week and she agreed to sample my acorns and I was nervous. Here's
Starting point is 01:16:57 what happened. I have one here. You can be completely honest. Okay, well it hasn't hit me yet. Oh, no, you should try this. It's more nutty. Like the bitterness of the end is so much better. You can be completely honest. Okay, well it hasn't hit me yet. Oh, no, you should try this. It's more nutty. Like the bitterness of the end is reminiscent of like a fresh walnut.
Starting point is 01:17:12 This is edible. You could dry that and make them and put it in a baked good. Verdict, edible. Jarrett then tried another. He said, oh, it was good. And that maybe he just got a weird one. So he remains my spouse.
Starting point is 01:17:27 Now I'm going to attempt to grind these into flour and make acorn cookies and I'm going to report back. But having a beloved and professional forager say, hey, you're not going to die from ingesting this and I found it pleasant is really enough of the goal for me. I'll let you know how it goes. All right. Be safe out there. Get those socks.
Starting point is 01:17:44 Bye bye. The pipes, the pipes are going.

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