Sawbones: A Marital Tour of Misguided Medicine - Sawbones: Diabetes

Episode Date: January 7, 2015

This week on Sawbones, Dr. Sydnee and Justin are gonna drink that sweet pee. Music: "Medicines" by The Taxpayers (http://thetaxpayers.net)

Saabones is a show about medical history, and nothing the hosts say should be taken as medical advice or opinion. It's for fun. Can't you just have fun for an hour and not try to diagnose your mystery boil? We think you've earned it. Just sit back, relax, and enjoy a moment of distraction from that weird growth. You're worth it. that weird growth. You're worth it. Alright, time is about to books! One, two, one, not a sense, the escalant macaque for the mouth. Wow! Hello everybody, welcome to Saul Bones, a metal tour of Missguided medicine. I'm your coach Justin McElroy and I'm Sydney McElroy

Sydney it's a new year and that means a new me a new you a new me that's exciting I'm gonna keep many of the classic features that people like yourself have come to know and love Like being being married to me. Will you keep that one? That one's there, but like I'm also gonna keep my demeanor, my sparkling personality, my- Your hair, will you be a hair? I love your hair. Yeah, the hair is definitely staying. Okay, good.

But I gotta get, I gotta tell you this year, I'm gonna get blasted, I wanna blast my core. Does that mean drunk? No. Is that like getting crunk? Is that what getting crunk is? No, that's not what getting crunk is. What I'm talking about is a full respect of my physical

visage. Basically blasting my core. I'm going to take my glutes. I'm going to take them out to the work shed. I'm going to shred them. I don't really think you know what glutes are. I'm going to shred my glutes. I'm going to take my pecs and my quads. I'm just going to put them in the muscle cannon and blast them.

Why do you want to get in the muscle blasting cannon? But there's this thing that you're saying. There's really Sydney, there's only one good reason to get healthy and get fit. Okay, there's only one. There's only one good reason to get healthy. I'd love to hear what it is. Tell me please. Babes. But.

For babes. Yeah, but like not to get babes. Okay, that's good. You're backing up from this. Okay, so why? To walk it back. So they are like, how are you doing? Just for your own self confidence,

for your own self confidence. Just for my own self confidence. You feel good about your glint. So when I walk past pecs and babes, they lower their sunglasses and are like, oh, you're a ujk. Do you do a lot of walking past babes when you're working out of the house every day?

Not now. Now I cross the street to avoid babes. I don't have my look right, but that is the one good reason I think to get shredded. I actually, I would have to argue that there probably are a lot of good reasons to get healthy. No, name one. Okay, one that I think is worthy of talking about would be,

so you don't get diabetes. Hmm. How do babes feel about diabetes right now? Well, I mean, I don't know that. I don't know that like babes as a as a like as a unit of babe like all of us feel a certain way about like I don't know if we are attracted or unattracted to diabetes. I don't know that that's a but you probably like that on your match.com profile like you have to put that like as a core you probably would prefer people didn't have diabetes. Well, I certainly would because I'm a doctor and I want everybody to be healthy.

Yes. Me too. We both have a history of diabetes in our family. Exactly. Which is why we should be worried about it and be healthier. But there aren't a lot of people in my family who are shredded and blasted. So correlation? I don't know.

Can I get the research lit out and maybe hit the books? I'm hit the gym. Why don't we talk about diabetes first? Okay, sounds good and then I'll go shred. Okay, then you can shred after this. I want to thank a couple people. Kate, Rachel, Paul have all suggested this topic. A lot of people have probably even before that.

And we just hadn't gotten around to talking about it yet. But it's an important one because a lot of people have diabetes. And as Justin mentioned, both of us could get it as we get older. So we definitely want to talk about it. Well, educate me. So first, do you know what diabetes is? I thought before I talked about the history. I have no earthly idea. Okay. I figured. I think a lot of people understand that it has something to do with sugar. Yes, right. Because a lot of people will tell me they have the sugar diabetes, which is not, I mean, that's not really a thing for say. That's not a different kind.

But it does have something to do with sugar or glucose. It's probably what I'm going to say a lot. So that's what I'm talking about sugar. Okay. So there are two types of diabetes. Type one and type two. Very good. Blu it up.

And students become the master. there are two types of diabetes. Type one and type two. Very good. Blu-blu-blu-up. And students become the master. The, in general, the idea is that your body is not using glucose the way that it's supposed to. The difference. Okay, before you get into this explanation, this is what is always confusing, right? Like, and as I'm speaking,

as a complete layman here, is sometimes people with diabetes have to avoid sugar, but then there's like that bit in steel magnolias where they have to get our orange juice or candy or something because she needs sugar. That's all from a young age. This has been very confusing to me. So, okay.

I'm in it, I'm sorry. No, no, that's okay, I'm gonna explain it. So your body doesn't use glucose the way it's supposed to. In type one diabetics, the reason is that you don't make insulin, which is the hormone in your body that helps you use glucose. So that's why we treat diabetics, especially type ones with insulin. We give it to them so that they can use that to use the sugar, right? If let's say that you took your insulin like you're supposed to, but then you didn't eat that day. Then what would happen?

Well, then your sugar would go too low, hence, jewelry or obverts, needing orange juice when she's in the beauty shop and still magna- yes. So if your glucose gets too low, that's what that really is really for. Diabetics don't naturally have low sugar. It's the treatments that give them low sugar. Okay. Well, that makes sense. Now, that says a post, so that's actually very,

the very small percentage of diabetics are type one. It's like 5% or type one. The majority of them are type two, which is the kind we worry about in our family because it has a high like genetic disposition. And this is, you make insulin. Your pancreas is still producing insulin, but it's not using it well.

It's kind of like, so insulin, think about it this way. Let's say you're trying to get into a hot club. Okay. The cells in your body are a hot club that you're trying to get into. Okay. Your glucose. I am. Okay. So in order to get into the hot club, you take insulin with you. She's like a really fly babe. A fly babe.

She's a fly babe. Okay. So if you're a... A babe. A fly babe. She's a fly babe. Okay. So if you're a... A lot of cool terminologies in this week's episode. If you're a type one diabetic, you don't have any fly babes to help you get into the cool club, right? This is just not there.

So you just circulate through the bloodstream, trying to get into cool clubs and they won't let you in. Because there's no fly babe. Is it, can I just say a fly girl like the backup dancers on in living color? Exactly, you don't... So trying to get in the club with a fly girl from in living color. And you don don't try to get in the club with a fly girl from in living color.

And you don't have J.Lo. Got it. If you're type two diabetic, you got J.Lo. Okay. So you're there. You've got the fly babe with you. You get to the cool club. They still won't let you in the door because the bouncer is.

I don't know. He's just maybe you know what it was more of a mad TV fan. Exactly. Okay. Or he's not into the ladies. Got it. And he's just maybe, you know what? He was more of a mad TV fan. Exactly. Okay. Or he's not into the ladies. Got it. And he's just, he's having none of it. Okay. So does that make sense?

Yes. So you've got the insulin. It's just not working the way it's supposed to. Okay. Okay. Which is why we treat that differently. We can give you insulin if you're a type two, but we can also give you medicines that will make your cells more receptive to the sugar and the insulin.

Got it. Got it now. And over time, over long term, it does a lot of damage to different body systems to your kidneys, to your eyes, to your nerves, your blood vessels, that kind of thing. So take me back to the beginning though. So diabetes is one of the first diseases ever described. If you go back to the ancient Egyptians, they wrote about some sort of wasting syndrome where somebody would pee a whole lot.

Okay. And that was probably diabetes. I actually probably describing type one diabetes at the time. Yeah, I would imagine that type two diabetes was not super common back then. Is that... It's probably not. And then the other part of that is that it would be

a lot harder to tell that it was one disease. Because if you think about it, the things that show up that are really easy to spot with type two diabetes are the complications that result from it. People go blind, people get sores on their feet and lose their toes or feet, that kind of thing. But with type one diabetes, it tends to present pretty dramatically.

You get it as a kid, you get really sick, you lose a whole bunch of weight, and you can go into something called diabetic ketoacidosis, which basically means like your blood sugar is super high and you're breaking down all of your fats, like ketosis, like you try to go into an acnes, you're breaking down all your fats to try to use something to keep your body going, you get really sick and you can die of that. So that was probably what they noticed as a syndrome because it was so dramatic. Right. Around the same era Indian physicians also were describing this probably the same thing, diabetes, only they called it honey urine. Honey urine, why is that? Because they noticed that the urine of a diabetic patient would attract ants just like honey did. If they're in ketosis, it also has a smell, a distinct smell. How do you know that, just because I was in ketosis when I was on

anacons and it was not pleasant. Yeah, I don't see. I have a problem with any diet that encourages you to go into ketosis, especially if you are a diabetic, I really don't like that. But anyway, so your urine would have sugar in it, so it would attract to ants like honey dead. And of course, both of these were associated with weight loss. The Greeks also noted diabetes. They came up with the name diabetes, which means to pass through because of all the urine that you're passing.

Oh. Because diabetics tend to pee a lot. You can think of high blood sugar as kind of dehydrating you from the inside out. It makes you just pee nonstop. So you're thirsty, you're hungry, and you pee like crazy. Okay. Those are the three things we ask people about with diabetes a lot.

We didn't add the follow up term diabetes malitis, if you've ever heard. That's the other part of the term. This is like formal name. If you don't know diabetes very well, that's called diabetes malitis. Exactly. And that was added in the 1600s, malitis meaning from honey. And it was to distinguish it from a different kind of diabetes called diabetes and sypitus. And we don't need to get into what that is because that's a whole other thing. Okay. But again,

it was just noting the fact that we didn't really know much about what was causing diabetes. We knew people lost weight, we knew they beat a lot, we knew their urine was sweet, and we knew that because by this time we were using water tasters, which were people who drank pee. Cool gig. To tell you if you had diabetes. Well, you know, if you have whatever. Cool gig. Reach for the stars, I guess. Stay in school. And maybe you too can be a water taster. Don't be fooled. It's not water. He's the best there is. If you want your urine, taste it by the best. You got to go to this one guy.

And this was probably incidentally how they figured out that there was another type of diabetes because people would have the syndrome they recognize as diabetes. When they were young and then they would taste their pee and it would be sweet and they'd go, oh, you've got that thing that at the time probably was going to kill you pretty soon. But then they also, because they tasted everybody's pee for every reason, tasted adults pee who were there for something completely different and they'd go, oh, now you're now your pee tastes like sugar too, but you didn't die when you were kid. I don't know what's going on with you. You maybe just have delicious pee.

It is just a genetic benefit of being you. And they didn't know what to do about any of this. Because they didn't have carbonation. What are you gonna, how are you gonna drink flat pee? That's no good. That's how Mountain Dew was invented. Did you guys know that?

That's true. Personally, I would believe that. I don't like Mountain Dew. That's just me. Speaking of diabetes. Yeah. Arateus of Capitoksia, which I really like that name. He first described diabetes as the melting down of flesh and limbs to urine. Cool, wow.

He was crazy. He was very graphic. Hapocrates largely ignored diabetes. He knew it existed, but he really didn't talk about it. And that was because there really wasn't a treatment. There definitely wasn't a cure. So, and that's kind of a, like I find that with Hepocrates, like that's his thing. If there's nothing to do about it, he usually doesn't talk about an illness.

Yeah, moves on. Like there's just no sense in it. Healthy approach though, living the now. Yeah. Focus on things you can't control. Yeah, I have no reason to talk about this because I have no idea what to do about it. And that was pretty much the attitude of most of the Greek physicians at the time. I don't know, exercise? Maybe it'll make you pee less? Maybe exercise? It was thought that horseback riding would make you pee less. I was just taking a

shot. Which I, I just think if you're out riding a horse for a long time, you probably can't stop and pee much. No, I would think once you get off the horse, it's like, yes. I've got a pee now. Time to pee. Maybe they just thought you'd be too respectful to pee on the horse. Probably, but not back then, because they got real. They got darting. Galen only ever commented on two cases, ever.

So, oh, he was another one of those famous old Roman physicians that we talked about all the time. Got it. I mean, the eye remember of course a Persian physician Avicena described it as well, but and he did come up with a treatment for it. This is all around the same time period He Recommended that you take some different herbs fin e Greek lupine and seduary seed and that that would help and actually this is interesting and Zeduary seed and that that would help. And actually, this is interesting.

Fenugreek does lower your blood sugar somewhat. Well, there you go. Yeah. He mailed it. So that is still something that you'll see people, like Herbalists use today as an, or like a holistic treatment. Nice job for that. And you got it in one.

Plenty, of course, had something to say about this. You know, Plenty got away in. Plenty of the elder, one of our favorite, our favorite characters here on Salvones, said exercise as well. Also, rubbing. I don't know what that means. Rubbing. Rubbing, especially in front of a fire. Okay. I don't know what rubbing means. It's, I mean, it's got to love yourself. Just's got to put your hands all over. She's like, rub. Do some jumpy jacks and rub yourself.

Whatever. Ooh, careful. My diabetes is gone. It's my urine. Also bathed, but seldom. Okay. Don't bat too much, but do bath. And then you should drink small amounts of dry wine

that is either lukewarm if it's winter or cool if it's summer. Okay. But only enough until you're not thirsty. I'm suspicious of anybody in this point in history who has like five things you could do for a thing. Oh yeah, I've got that way, way down. Here's five different things that I know will work.

Yeah, also animus. Sure, well, of course. Yeah, no, why not? It goes without saying. It follows fails, animus. It's interesting if you go back to a Chinese physician, Wang Tao and 752 A.D., he advised the you eat pork pancreas to treat diabetes.

Oh, sure. I bet that's just delicious. Which is fascinating. Well, I'm no think about it. The pancreas, I mentioned that, makes insulin. Wow, so that was a good call. Yeah, I don't know how he would have, I have no,

and this is not me suggesting that he knew that, but it was a good guess if he didn't know something. Yeah, that's a done. But in general, you know, I mentioned some treatments. Unfortunately, at this time, it was kind of considered a death sentence, you know, when you recognize this syndrome in a kid or a young adult, you pretty much just knew they, they weren't going to last very long. And for adults who were actually having type 2 diabetes, which they only vaguely understood as an entity unto itself, they were probably going to die of some of the terrible complications. So my spirits are down now.

Pick me up. Tell me about some more crazy treatments. Well, I'm going to do that in just a second, but real quick, why don't we head on down to the billing department? Let's go. Okay, Sid, so other treatments, hit me. Okay, so like everything else we've ever talked about, bleeding was tried for diabetes. You gotta get it out.

Yeah, I mean, why not? We have, when, what is what is it when all you have a hammer everything looks like a nail. There you go. Yeah, so cut everybody. When all you have is a razor, you can cut people I guess. That's a good you should write that your back poor Richard. Come on to you. In the 1700s, it's interesting. They actually started to advise dietary changes. Specifically, a connection was made between that there is sugar in food. They figured out that the thing that made urine take sweet was sugar. And so maybe if they reduced, what's, OK,

let's not go overboard with the back padding on this one. I mean, the urine was sweet, then the sugar was sweet, and they made a connection. I-I don't get a medal for this one. Well, eventually we had to make up a test that actually said there was sugar in the urine, you know. Is it-we use it to sit-the sip of rue? The sip. We didn't know anything. We knew we have p-tasted sweet.

We didn't know there was sugar in it. We know that sugar tasted sweet. What other explanation can we have cooked up? We didn't have stamy, huh? We didn't have equal. That's not very scientific. Okay, fair enough. You'll get your turn in a second.

I'm down, sheesh. So anyway, they told people to eat less sugar, eat less carbs, which was actually probably a pretty good idea. What's funny though is that in the next century, the next hundred years, French physician flipped it on its ear and said, you know, people are still dying of this diabetes. Maybe, maybe we should eat lots of sugar. Excellent. Good job. Try that instead. Just eat a whole bunch of sugar. They never saw that one coming.

That really didn't work. In the 1900s, as we enter like the heroic era of medicine, you, of course, there were like a million different treatments for it, you know, because everybody was trying something. Right. Probably all based around cocaine. Yeah. Well, the definitely opium was a popular treatment. So why not? I'm sure cocaine was tried,

because I mean, I mean it's cocaine. Probably made you feel good. Yeah, it's good for what nails you. There were a lot of different dietary cure, so one was called the oat cure. So you mix eight ounces of oatmeal and eight ounces of butter and eat it every two hours. That's called the Wilford Brimley diet. You wonder why Wilford Brimley has the diabetes. That's why.

There was also the milk diet, which I presume was, you know, drinking. It's actually not great, because milk has a surprising amount of sugar. Yeah, milk, no, that's not a good diet. Also, there was the rice cure. I like that they went, they were like, everybody's, you know, oatmeal. Yeah, milk, no, that's not a good diet. Also, there was the rice cure. I like that they went, they were like, everybody's, you know, oatmeal, diet, milk, diet, let's call it the rice cure. No, still doesn't work. There's potato therapy, which I will say,

I like potato therapy when I'm like, down and it's a rainy day. I read a story about it in Cosmo. Potato therapy is the hottest thing. I need to match potatoes. There's a rainy day. I read a story about it in Cosmo. Potato therapy is the hottest thing. I need some mashed potatoes. There's some french fries. There was also overfeeding. So a lot of type one diabetics tend to lose weight as they're entering into the becoming a diabetic.

Losing a lot of weight, it can be pretty dramatic. And especially if they're untreated and suffering from diabetes. So they thought, well, I don't know, maybe we just feed them a whole lot. Maybe. Just eat as much as you can. By 1915, though, there's a Dr. Allen out of the Rockefeller Center who was the Rockefeller Institute, who was studying diabetes a lot, And he said, he thought, actually, that all these ideas about different foods to eat

and eating too much, that this was the opposite. And that what we really needed to do was starve people. Okay, well, that's an option we can certainly try. So he would admit people to the hospital, take, because this was an intensive therapy. So you have to start it off in the hospital. Clear your schedule. Admit them to the hospital and give them

black coffee with whiskey every two hours. All right. This is the best drink that we've ever had. Now, if you don't drink, you did have the option of drinking clear broth every two hours. That's how you know that a curi's legit if they have an option for T total or something. Oh, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, because it's just coffee and whiskey. Then you fix the diabetes. It usually took about five days.

And then at that point, he would put them on like a super strict diet that mainly involved just not eating much. The scary thing about this is that for type ones, especially who had been diagnosed and were still untreated in a little bit of time and past, they would probably have starved to death with this treatment. Not great. No, no. So not a good, not a good therapy, I'd say. No.

So around all this time, in the late 1800s and 1920s, we were making great strides into understanding, you know, what, what was diabetes and what could we do about it? And some really interesting things that happened were a couple doctors, Vaughn Mirin and Minkowski, were trying to figure out what is this organ the pancreas do. Now at this point, they didn't know it was related diabetes yet, but they didn't know what the pancreas did.

And so Justin, if you had an organ and you wanted to figure out what it did, what would you do? I would take it out and see how I felt. Okay, maybe not of yourself. Okay, take it out of something I hated. Okay, that's illegal. Okay, I'm out of ideas. Well, but you're close.

So they pretty much did that. They were debating, what is the pancreas doing? They said, hey, why don't we get some dogs? Take out their pancreas. Oh, sorry dogs. Yeah, sorry to all you dog lover. But hey, on the bright side, considering all of medical history, at least they didn't do it on developmentally delayed people. So that's good.

That's true, and they didn't do it on women. Hey, that's great. That's terrible. They didn't do it on homosexuals. So hey, I think it's a big win for everybody. Good job, medicine and sorry to Peter. So they took out some dogs, pancreases, and the dogs basically just started peeing everywhere.

They checked the urine of the dog and they found glucose. I don't think they were tasting it at this point. We had to test. Let's hope they were drinking dog pee. Let's hope we were past that point. And so they were like, hey, we gave these dogs diabetes. Clearly, there's something in the pancreas that keeps you from getting diabetes. But they had to figure out which part of the pancreas that was because initially they tried to treat it. They didn't, but years later, people who followed up on this research

tried to treat it by just taking like pancreas and grinding it up and injecting it into dogs that had had their pancreas removed, you know, to try to replace it. And you're also giving them all kinds of other things that the pancreas does that well aren't very helpful when injected in this manner. Right. So there were a lot of bad side effects to that treatment. Throughout these years, and a lot of scientific research that you probably wouldn't find very interesting to be honest. We figured out- A little juggie, but that's fine.

Well, I'm just, you know, do you want me to go into how we isolated the islands of Langerhands? No, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no, no You were dead on the first time. Anyway, we figured out that there was a part of the pancreas specifically, the eyelets of Langerhands, that produced insulin.

And the insulin was the thing that did most of the work, so that if you could take insulin out and inject it back into the dogs, they'd get better. There were lots of people who were working on this research, lots of people who did different parts of it, but the two main guys who get a lot of credit are Frederick Banting and Charles Best. From this research, they actually developed insulin therapy. They figured out that, there was this molecule, we could isolate, they mainly did this in pigs, also cows, and you could inject it into humans and it would lower glucose. When you read the stories of the first patients that they treated this way, it's pretty amazing.

These were largely kids, teenagers, 14-year-olds who were hospitalized, dying from type 1 diabetes. Nobody knew what to do. They were starving these kids to death. They came in, gave them insulin, and gave them, I mean, just totally turned their lives around, and gave them many, many more years. It wasn't a perfect therapy at the time, of course. There was a lot more to do, but you know, they saved lives. Can I ask a dumb question, kind of a stupid question about insulin? So we figured out that insulin is the thing

that makes your diabetes, that was like the treatment, right? That it was an insulin issue, right? Yes. So how do we get, this again, I feel so stupid. How do we get more insulin? Like especially in these times,

like, was it synthesized? Is it like insulin? Now it is. Now it is. Now it it synthesized? Is it like, it's in now it is. Now it is. Now it's synthesized. Then they were, like I said, they were getting it from pigs and cows. Okay. But now they have, you know, biosynthetic insulin that they use.

And this worked really well. Now for type two diabetics, this would not have been as good. I mean, it does work. I mean, of course, we use insulin for type two diabetics, but like I said, it's the sensitivity. It's how well your body uses the insulin. For type one diabetics, this was definitely revolutionary. The really cool thing about this is that they developed the therapy and they made it freely available for companies to produce and use. They didn't trademark it. Patent it, no.

No, they didn't. Yeah, no, they didn't. They didn't want to control commercial production. They wanted it to spread as quickly as possible. And as a result, they probably saved a heck of a lot more lives because then, you know, of course it was cheap. Good on you all. Yeah, yeah.

Now, of course, we have many different insolents than a lot of them are brand names. And that largely has to do with not the insulin molecule itself, but how it's Yes, how is flavored which if you've strawberries insulin? Why are they always weakening it? That seems like so counterproductive No, it's it has to do with how long acting it is how quickly it's released in your system that kind of thing right on After that, you know after the insulin therapy, which was really the big breakthrough long acting it is, how quickly it's released in your system, that kind of thing. After the insulin therapy, which was really the big breakthrough, then we began to develop other medications that worked on different parts of the glucose process.

So there came medications that called sulfonyurea, that stimulated the pancreas. They were later metformin, which is like the mainstay of type 2 diabetes therapy now. Right, I've heard of that one. It's funny, because we're developing all these diabetes medicines. We're understanding diabetes so much more as we move through the 1900s. But in the 1950s, we were still advising diabetics not to get married to each other.

Yikes, really? Yeah. Because we didn't want them to give diabetes to their kids. Right. Which also, it took us a while to understand that it's really type two that has such a high genetic component, which seems weird I know because type one is the kind of kids get automatically.

Throughout these decades, a lot of natural treatments have been tried. I already mentioned the finia greek, which does have some effect on blood glucose. But cayenne pepper, turmeric, ginseng, fish, dark chocolate, coconut oil, blueberries, red grapes, green tea. Any of these things, some of them have been studied, some of them haven't. A lot of the time, it's like a small study

that if it was done, there was a small study done, it didn't have a lot of people in it, it wasn't very well funded. And I think I've said this before, something like, you know, I don't know, buckwheat or ginseng or turmeric, we're never really going to have the kind of high powered study that you would for a brand name, you know, pharmaceutical. Because there's no money in it. Right.

Because there's no money in it. Get your buckwheat. Right. Unless you're the owner of the little rascals franchise, in which case I assume you have trademarked the character of public. Right, but he does not treat diabetes that- I know, but again, the money's not gonna be there for that. That I know, nobody's gonna do that.

So who knows, some of these things have shown effects and small studies, others have said, nah, this stuff doesn't work, like sentiments, a big thing like that. Like, who knows? Certainly doesn't hurt to eat some almonds or blueberries. Now, diabetes is a big issue in this country. 26 million Americans have diabetes. 79 million more are prediabetic, which means that they will develop diabetes within the next 10 years. If they don't do exactly what you were gonna do honey. Get shredded.

Well, to get healthy. So, you know, take care of yourself. So listen, y'all. Oh, and I didn't mention they're also insulin pumps now. These are really cool. So that it, like, it's like an external pancreas. Like, it's a little pumpy wear and it gives you insulin all the time and then extra doses of insulin, you eat it's really cool. And then we're working on things like pancreatic transplants. I used to wear fashion insulin pump. It's not functional, just sort of accents on my outfits. So listen, it's kind of like you used to want to wear glasses. Yeah, exactly,

but this is different. So listen, so boners, it's me, Justin McRoy here. Let's say this opportunity, you and me and all of us who are in that pre-diabetic camp to take this moment and say, hey, I'm gonna get healthy this year. You know, jokes about gang shredded aside, it's really about getting fit and sticking around for as long as you possibly can. And remember, again, and I have to keep reminding myself

of this all the time. If you're waiting for a weight loss miracle or the exact right diet or nothing, the only way to lose weight is to make a dozen really hard decisions choices every single day. And that's the really grueling work of it. Anybody can stop eating carbs for a couple of months. It's deciding every day that you're gonna do your best for yourself

But start today right now and also a lot of diabetics don't know their diabetic Free diabetics don't know they are so it's a good thing to talk to your doctor about whether or not you need to be screened for it because You may not know Thank you to max fun for having us as part of their family We we really appreciate it. There's a ton of other great shows for you to check out We've got a new one called the Adventure Zone that my brothers and I do with our dad, where we play D&D and we record it and people seem to enjoy it against all odds. There's destination DIY. There's maybe geniuses. There's a great pop culture show called Bullseye that you'll want to check out. There's a ton of great stuff on there on the Maximum Fund that was my brother, my brother,

my brother, my brother, my brother. Whoa, we my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, my brother, brother, my brother, my brother, my brother, my brother, my brother. We have a new one almost every Tuesday, practically every Tuesday. Thanks to people tweeting about the show, helping us spread the word like Joe Leonard, Nick Bristo, Vanessa Val, Alstein, Vanessa Van Alstein, excuse me. That gentleman's name is just a mathematical formula. I'm not going to try to pronounce that. Josh Marks, Michael Bosset, Prachika, why so many others.

Thank you so much for tweeting about a show. We're at Sub-Ontos Twitter, so you can check us out there. And that's gonna do it for us until next Tuesday. I'm Justin MacRoy. I'm Sydney MacRoy. As always, don't drill a hole in your head. Alright! Maximumfund.org Comedy and Culture.

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