Sawbones: A Marital Tour of Misguided Medicine - Sawbones: Monkey Escape

Episode Date: November 4, 2025

Sometimes we like to have fun on Sawbones, like diving into a recently reported story of a truck full research animals who escaped and were infectious to humans. But what actually happened, were these... monkeys infected, and what is the purpose of monkeys being infected in the name of science in the first place?Sawbones audience feedback survey: https://forms.gle/kLXiFU8iRzAazPyn9Music: "Medicines" by The Taxpayers https://taxpayers.bandcamp.com/Native American Aid: https://nativepartnership.org/naa/

Transcript
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Starting point is 00:00:00 Sawbones is a show about medical history, and nothing the hosts say should be taken as medical advice or opinion. It's for fun. Can't you just have fun for an hour and not try to diagnose your mystery boil? We think you've earned it. Just sit back, relax, and enjoy a moment of distraction from that weird growth. You're worth it. All right. Sorry is about some books.
Starting point is 00:00:30 One, two, one, two, three, four. Two, three, four. We came across a pharmacy with us windows blasted out. Pushed on through the broken glass and had ourselves a look around. The medicines, the medicines, the Estelle and McCormack. for the mouth Hello everybody and welcome to Sawbones Marital Tour of Misguided Medicine
Starting point is 00:01:08 I'm your co-host Justin McElroy And I'm Sid. The hardest thing about doing video stuff, Sid, is that I have to fight my compulsion to always be crisscross applesauce in a chair like a baby. That's the way I always sit and it's very hard to not sit
Starting point is 00:01:24 crisscross apples like a baby even though I know that it is bad for my posture and my health to sit that way. it's just the way I do it I understand because for the longest time at my office my clinic I have just been sitting on a stool specifically
Starting point is 00:01:40 our hairdresser uses the saddle stool and I was so impressed with this like saddle shaped stool I thought it was so cool that Justin got me one for my clinic and I just roll back and forth because it's a very small clinic from my desk to like my lab to into the exam room back I'm just always mobile like on wheels
Starting point is 00:01:58 and it's great except it's killing my back But I look so cool rolling around on my stool, I think. You look cool. Do I? No one has that. Well, even if you don't, you're gone so fast. You don't hear them make fun of you because you're on your stool. You're like, zoom, you're gone.
Starting point is 00:02:11 Now I don't know. Now I'm questioning. What would, can you imagine a conversation that someone would feel comfortable having with you where they're like, Sidney, we have to talk about the stool? I mean, you would though? Would I? Justin bought me a stool with a little like lumbar support, like back, tiny thing on the back for me to start using, ostensibly for my back pain.
Starting point is 00:02:33 However, is it because I didn't look cool? No, you look so cool, babe. So cool. Hey, speaking of cool stuff that's happened, you were telling me about a headline you were reading. And I said, wait, wait, wait, Sydney, you could keep telling me about this. And I'd love to hear it. But I'm going to deprive myself and say, let's record it. Let's record you telling me about this.
Starting point is 00:02:56 so we can really unpack this medical history as it happens. So, Justin, I thought we would have a little fun today. Okay. I know that while you're listening to this, it is after Halloween, but we are actually recording on Halloween. And anything, as Mr. Curry says, anything can happen on Halloween. Anything can. Now this...
Starting point is 00:03:17 I read a story on Facebook today that when he originally filmed that scene from Worst Witch, he and the woman who was the head played the headmaster of school was a friend of his and she had brought a bottle of slow gin that the two of them drank all night and he said it kept them very warm but apparently it wasn't great for their concentration because it was basically unintelligible and they had to make them reshoot the entire scene when they got back to London in the studio but the end of the story was Tim Curry said but hooray for gin yeah
Starting point is 00:03:49 hooray for gin and the lyrics to the song I don't know that it matters. No, it is a very sort of like ambling, ambling narrative. Is that why the line, has anyone seen my tambourine? He might have just been sloshed like, I know I had it around here a second ago. Justin, this story did not happen on Halloween, but it sounds like the beginning of kind of a fun, scary movie, I think.
Starting point is 00:04:19 One of those 28th. Yeah, one of those 28s. It could be the beginning of a zombie movie. So I heard this story initially, I was at work, and my very dear friend John told me this story, like, did you read about this in the news? And I, he is a brilliant doctor of psychology, and he did get some details wrong initially. Now, I do like his version of the story better. Okay. So thank you, John, because my, this is what made my imagination run wild.
Starting point is 00:04:45 The original story said is, did you hear about that truck somewhere that had like 50 monkeys in it? And they were all infected with COVID and herpes and hepatitis and it crashed and all the monkeys are loose. I mean, chilling, can I say? Chilling, yes. Chilling, but in the year of our Lord 20205, a mere Tuesday, I would say, honestly. Very impressive, but not out of the realm of possibilities, as I understand it currently. Yeah, no, it felt right. Yeah, it felt right.
Starting point is 00:05:16 And you have to know, when I heard this, I initially did not question all of the details. Because I thought, yeah, sure. Sounds good. Yep. That sounds right. Yeah, truck full of monkey, super sick crashes. Why wouldn't it? No.
Starting point is 00:05:30 The reason that John got some details wrong is actually not his fault. It was that the initial reporting of the story was a little inaccurate. There were some, I don't know. I'm going to unravel this. There was some confusion as to the nature of the monkeys in terms of their health status. It's important monkeys. Know your status. It was confusing as to how many monkeys there were initially and what the threat to humans was.
Starting point is 00:05:57 And so there were some initial details that were released that were wrong. And that was in the news. And then corrections were released. But there's still, I mean, there's a grain, I don't know, there's a grain of truth in this story. Media is often the first draft of history and it can take a couple passes to figure out exactly how many monkeys were on there, what kind of viruses and illnesses they had. if they're in funny costumes at all. That's a huge thing with monkeys sometimes is if you are going to be doing research,
Starting point is 00:06:26 are you putting them in funny outfits that look like people? Are you dressing like a ballerina or firefighter? Well, I don't know I will say, are you even doing a calendar with them? No one commented on whether or not the monkeys were in costume in any updated or previous versions. I'm just saying if they're going to do monkey research, there should be someone whose job it is to play with the monkeys
Starting point is 00:06:46 and make sure they're having a lot of fun and whimsical. time. Sure. No, that makes sense. Okay, good. Okay, so what actually happened? I don't know. There's a truck transporting research animals. So, Rhesus macaque monkeys. Research.
Starting point is 00:06:59 Rhesus monkeys. They're the monkeys. Oh, yeah, I know about the rhesus monkeys. What do you know about rhesus monkeys? They're really important in evolution. And they're important in DNA. And if you have seen movies where monkeys infect people. Ponnet Square.
Starting point is 00:07:16 It's usually a rhesus monkey. Like, I think that in common understanding of what is a rhesus monkey, people are like, well, that's the one that got everybody sick in outbreak or something. I mean, like, right, like, isn't that what we, if you have any sort of cultural understanding, you think about the, are these the monkeys that have things that you can catch? You can catch things. That's not really fair, the rhesus monkeys. That's really our fault. Yeah, but they're not max fund owners, so whatever. So they were transporting research animals from Tulane National Biomedical Research Center.
Starting point is 00:07:45 and the truck overturned on Interstate 59 in transit. It was just north of Heidelberg. Four lane, ironically. This is in Mississippi. There were 21 Rhesus monkeys on board, not 50. There were 21. I mean, if they're running at you all at once, that's still a lot of monkeys. I'm not thrilled whether it's 50 or 21.
Starting point is 00:08:09 Either way, I'm running the other direction. I feel like if I'm a truck driver and I have 20 monkeys, in here and I'm looking at the truck like guys I don't know I don't know I don't know and they come to you and they're like we gotta get another 50 monkeys in this bad boy there's no way there's absolutely no way you can't account for 50 different monkeys
Starting point is 00:08:29 all those personalities bathroom breaks all that is too much structurally they might write Hamlet eventually but you're gonna have to stop for the bathroom like constantly I don't think that the truck driver was worried about stopping for the monkeys to go to the bathroom okay he's gonna have a big cleanup but I guess It's his truck.
Starting point is 00:08:46 Now, what the, but the truck driver is where some of this information starts. So what was initially reported, so this truck carrying 21 monkeys did go off the interstate and flip. Okay. And the monkeys did escape. Yeah. Okay. Those are true elements.
Starting point is 00:09:03 Did they escape before the crash? No. That would be might think about this for a second. Not that I'm a way. Yeah, not that they would tell you, but I saw, I've seen all the kingdom of the planet of the apes movies, and I don't remember them, but I've seen them. on planes and stuff, and I feel like
Starting point is 00:09:17 maybe they started like, I feel like 21 monkeys heck, 15 monkeys working together could take the truck. If they, yes, if they were cooperating. 15 minimum. But I mean, they probably are, like, they're social creatures.
Starting point is 00:09:33 They probably were cooperating. Yeah, but how do you, like, get it going? It's a complex thought. Somebody has to be the leader. That's why they have to develop human speech. In the Plaint of the Apes movies, which I've seen but don't recall.
Starting point is 00:09:46 They do develop human speech. I believe that is an element of them. Well, and I will say that the reason that Rhesus monkeys are so often used in research is because we share about 93% of our DNA. So it's a good model if you're trying to figure out a disease or a treatment or a vaccine or whatever that would work in a human. Makes sense. I would also say up front, I am going to be interchangeably using monkey and apes. I'm 44 years old. I'm not doing it.
Starting point is 00:10:15 All right. You are going to get emails about this. You're going to get emails about this. I'm 44. I'm not doing this. I'm not doing crocodile and alligator. I'm not doing it. Okay?
Starting point is 00:10:25 I'm not. I'm sorry. I'm not going to get it right. And I'm not going to learn at this point. So monkeys and apes, crocodiles and alligators. Dinosaurs and dragons. It's all the same. What about frog and toad?
Starting point is 00:10:35 Yeah, frog and toad is a really good one. Actually, frog and toad, 100% same thing. Ribbit? Got it. Got it. The ribbit ones. Listen, Listen, just when you write. Keep it up, keep it up, man. Keep it up. Frogs, I'll put you in with lizards.
Starting point is 00:10:48 When you inevitably write the emails complaining about this, and I know some of you will, please just address them to Justin. Please make it clear that I did not admit this crime. I won't, you can't get to me. This is not on me. Okay, so the initial report from the Jasper County Sheriff's Department, this is the initial report from the sheriff. The driver of the truck, this is a quote, told local law enforcement that the monkeys were dangerous and posed a threat to humans. We took the appropriate actions after being given that information from the person transporting the monkeys. He also stated that you had to wear PPE, personal protective equipment, to handle the monkeys. We actually said PPE equipment, but we'll forgive that. And then went on to say the monkeys were infected with herpes, hepatitis C, and COVID-19, and therefore were endangered humans. And then even if they weren't infected with these diseases, they also are aggressive. So stay away.
Starting point is 00:11:45 So this was the information that was initially released. And it led to some great headlines. Monkeys with COVID and STIs escaped in Mississippi. There were lots of those. You can look them up. Now, that's not entirely accurate anymore. And hopefully all those sensationalized stories have been updated. What do you think?
Starting point is 00:12:03 Have they all been? I can't imagine that people are going back and taking the time. And we can hope. But yeah. Are we still talking about the driver or are you moving on for the driver? I was going to move on from the driver. Would you like to talk more about the driver? Yes, I would like to say that they're trying to hang this driver out to dry for this, for this information.
Starting point is 00:12:23 That's what, yeah, they're like, the driver told us. Okay, imagine I'm the driver, though, okay? And my job in science is truck driver of the science, right? I'm driving the science. You're driving the monkeys. And they're like, you flip the monkeys out of your truck, which is, I would say, the number one thing you should not do. Don't let the monkeys escape. If they come to me and they're like, are these monkeys dangerous?
Starting point is 00:12:48 Should we be careful? I would look at them and say, absolutely. Number one, don't ask me. I drive the truck. Absolutely. You should take every single care you can. How many monkeys are back there? I don't know.
Starting point is 00:13:03 I didn't count. I drive the same way if there's 20 monkeys or 50 monkeys. You should act like there's 50. I don't know how many are running around. They could be sick as all guys. Get it out. Just be really, really careful. Well, but it's weird. Okay. I know what you're saying, and I do think that when it comes to escape monkeys, we should kind of take, like, when you're working with infectious materials,
Starting point is 00:13:25 when you're working in health care, you're often taught the sort of, the idea is anyone could be carrying a bloodborne pathogen. So you should always be protecting yourself and your patient, as if that is the truth, right? You don't need to know, does this patient have something I could catch. You should be operating in a way that assumes they could. Right? I mean, that's the safest way to always, you know, protect yourself. And so I do, I agree with that. However, however, specifically, where did COVID hepatitis and herpes come from? Covering his bases. He's just covered his bases. He didn't know. Why those three of all? He knew it was one of the bad ones and those are the ones he could remember off his head. Don't come to someone who's just made the biggest whoopsie
Starting point is 00:14:04 of their entire life and ask them if caution should be the washword. Obviously, they're going to say, Yes, take every precaution. They could have, I don't know, COVID, hepatitis, herpes. That's all the ones I can think about at the moment, but they could have any of it. Please be extremely careful. And then they're like, he said he had three different things. Trust us. Trust us, guys.
Starting point is 00:14:22 This guy, this guy is a straight shooter who knows what he's talking about. I mean, the sheriff's department. This guy just up into the truck full of monkeys. Do not ask him questions. The sheriff's department felt confident enough that they released this information. Now, this guy felt confident enough that he released the monkeys. We shouldn't be listening to him. Now, Tulane officials reached out to the sheriff's apartment and said,
Starting point is 00:14:42 whoa, whoa, whoa, whoa, whoa, hold on, hold on. First, they wanted to make it very clear that these were not their monkeys. They're not our monkeys. Yeah, they were not in charge of transporting them. They were not in charge of the company that was transporting them. We're not, honestly. No, I mean, they might have come from our facility, but these are not our, we are not, we will help you, but this is not us.
Starting point is 00:15:01 Tulane did not do this. He would say, don't blame. Not our monkeys, not our circus. Okay. They did. And they said, but we can assure you they are not infectious. And so later... Not our monkeys, but they're not infectious.
Starting point is 00:15:15 Okay. Later, Sheriff Randy Johnson came back out and said... Yes. The monkeys are not... They are not harboring disease. They are not dangerous in that way. Nevertheless, Johnson said the monkeys still need to be neutralized... This in quotes, because of their aggressive...
Starting point is 00:15:36 nature. And Tulane went on to say, you've been talk, you've talked so much after you said Randy Johnson. Okay, go ahead. Tulane did go on to say that the 21 monkeys had recently received checkups confirming that they were pathogen free. So they just got checkups at Tulane. They are, they are not carrying any illnesses. And it's not our problem. That's what Tulane said. And Randy Johnson said, I don't know, I was just repeating the truck driver. Randy Johnson also, is best known for annihilating a bird with a fast pitch. So I don't know if we want to be taking his word on anything animal. I'm assuming it's a different Randy Johnson.
Starting point is 00:16:15 Have you ever seen that video, though? I have seen that video. It's terrible, obviously. I'm sure Randy's still being himself up. And I doubt it's even the same Randy, really. If you think about it. I mean, statistically, it probably isn't. But let me say that obviously there was a lot of miscommunication,
Starting point is 00:16:32 misunderstanding, something happening in the early reports of this story. It could be. Maybe that's where the root of it was a Randy Johnson condition. They were already, like, the guy who threw the ball. But, like, no, but it is, I mean, it begs the question, one, why did they think these monkeys had these three diseases? And two, I mean, for me, it was a fun thought experiment. What is the danger to people? Like, what are we really talking here is the threat of these?
Starting point is 00:16:58 And also, by the way, all 21 monkeys did not escape. Only six escaped. I will say, as of yesterday's reporting. They didn't know. sorry three are still at large three monkeys are still at large how did they get it wrong whether or not all the monkeys were gone honey why did they think they had herpes i was trying to defend this guy but in terms of whether or not there's still monkeys in there that one should be easy i mean if you and and again three three monkeys are still at large at the time of this recording they may have
Starting point is 00:17:29 i don't know maybe they're caught now but three monkeys are still at large uh they still should be considered a threat because they could attack a human. So, like, don't approach them. If you're in this area, please don't, if you see one of these monkeys called the authorities, do not try to talk to the monkey or, you know, capture the monkey yourself. I would also build on that, say, and Sid and say, not just these monkeys. I would say if you see any monkeys in public, you should not try to apprehend them yourself. Yeah, don't, don't try to apprehend them. They are so strong. I don't know if you saw Chimp Crazy on HBO Max, but they're extremely strong.
Starting point is 00:18:04 So, yeah, don't approach them. Now, I will say, that was another thing. The reports of how big rhesus monkeys are varied wildly. Like the initial, one of the headlines, I think, like, from the New York Post was, like, 40-pound monkey with STDs on the loose or something like that. It's like headlines about King Kong, like murderous monkey rampages through city. There were later, like, accounts where they were like, well, average rhesus monkeys are about 21 pounds. So, you know. That's what makes these scientifically juiced rhesus monkeys all the scary, right?
Starting point is 00:18:31 How do they double their sun? So I want to talk about this thought experiment of what happens when monkeys escape if they are infected with some sort of agent. But before we do that, we do have to go to the billing department. Let's go. The medicines. The medicines that escal make macabre for the mouth. It seems wild that we get paid to do that what we're doing, Sidney, hypothesizes about monkey disaster, but. Let's not hypothesize about monkey disaster for a second, because if you could just speak on this real quickly, monkey disaster, this is not a, it is so close to, it is at the core of why you became a position.
Starting point is 00:19:14 Monkey, monkey disaster is sort of your heart and, is your heart and soul. I guess, I guess kind of, yes, in the sense that I, and I have said this, I think, I'm on the record saying this. She can't walk it back. I can't walk. I mean, it's the truth. And I, I don't know, as I get older, it seems sillier, but it is still the truth. I was inspired to go into medicine when I read the book The Hot Zone when I was 12 years old and I learned about hemorrhagic fevers and the idea of trying to find where did these where did these viruses cross from animals into humans when did that happen how did that happen and then using those sorts of that sort of research to then find effective treatments
Starting point is 00:19:52 vaccines cures whatever for viruses that was and yes a lot of that story involves monkeys So there you go That is very true Justin I will say This is not the first time That research monkeys have escaped This I mean
Starting point is 00:20:09 This happens more than you'd want to think about They're so smart They're so smart They've seen the inside of the lab Of course it happens a lot They're smart And I think that If you
Starting point is 00:20:20 You know you get used to working with them And I don't know All it takes is like You don't close one cage really You don't latch one door To talk about how easy it is to let monkeys escape because it is a problem. Well, last year, just last year, in November,
Starting point is 00:20:36 43 rhesus monkeys, so all 43, not six, 43 rhesus monkeys, escape from a biomedical facility called Alpha Genesis in Yamassi, South Carolina, because somebody, like, forgot to latch a gate. I mean, it was that simple. Somebody didn't lock something. Are we serious with this?
Starting point is 00:20:53 43 monkeys escaped into the surrounding area. Alpha genesis, have you not seen? in an episode of Black Mirror, for God's sake. Alpha Genesis? In the desert? And you let monkeys escape from it? No, no, no, no. We're in South Carolina, the desert is in South Carolina?
Starting point is 00:21:12 No, no. How did you turn South Carolina into a desert, you maniacs? What are you doing? It does feel, it felt to be like the beginning of a video game. Alpha Genesis, released 43 rhesus monkeys. They were young and they were healthy. and it took them, I will say it took them a total of two months to round up all of the monkeys. It was not until January of this year that they found the last of the monkeys and got them back to the facility.
Starting point is 00:21:39 And they have a cute picture in like the news stories where they followed it of one of the monkeys that they captured like back in the lab eating a peanut butter and jelly sandwich. Like, I'm home. What a wild day. Yeah. Well, I mean, I don't know. Two months. Two months they survived. Anyway.
Starting point is 00:21:56 So this is a thing that happens. I don't want to just blame this one truck driver, and certainly Tulane wants you to know it was not them. I would say if it could get out of Alpha Genesis, I'm not going to blame this truck driver at all. That's got to be the most vulnerable point for an escape, right? That's what they're planning on. Well, if you think about like in heist movies or in even movies like superhero movies where the villains being transported to Arkham or whatever, you know what I mean? That's when you break out. That's when you get loose.
Starting point is 00:22:26 Yeah, absolutely. That makes total sense. Yeah. So I want to talk about this thought experiment. What if they had been infected? First of all, the fact that I heard this, and I didn't immediately think, well, obviously, you wouldn't infect them with all three. Like, why would they be infected with all three?
Starting point is 00:22:42 I don't know why that didn't give me more pause. And I, as a scientist, feel bad about that. Because I don't know what science you're doing if you're infecting this one monkey with herpes, hepatitis C and COVID-19 just to see what happens. That's not... It's like TikTok science. Yeah, that's not a... So already, I cannot imagine a research scenario where you were just giving a bunch of monkeys all three of these things and then like, now let's put them in a truck and see what happens. That's not, why would you be doing that? So already this doesn't make sense. But let's talk
Starting point is 00:23:19 about it one thing at a time. First of all, the question has to be, if they're going to spread disease can you catch that disease from the monkey um yeah that's first for question one can you get COVID from a monkey can you get COVID from a monkey now it is true that many if not all non-human primates can carry COVID-19 we have seen this recess monkeys were used in some of the early as we were trying to understand in those early days of COVID can you get it more than once there were early studies on recess monkeys giving them COVID and then trying to reinfect them with COVID to see if they could. Oh, man, wasn't that a bummer? Wasn't it? You remember what a bummer that was, everybody? Remember when we figured out you could get COVID more than once? Man, we were really
Starting point is 00:24:01 hoping that wasn't the case. Hachimachi. Oh, boy, that was a bummer. Now, I will say what's interesting is that when it comes to, is this a zoonotic disease, meaning, or is this something we catch from animals? The research on COVID has not indicated that, absolutely, while there are many animals that can catch COVID, we know that that's true. that in terms of a huge reservoir of disease that is spreading to humans on a regular basis, animals don't really play a big role in that. I found a study that conclusively proved that a hamster gave somebody COVID. Or at least it looked like it did.
Starting point is 00:24:38 They felt pretty confident that the person got COVID from a hamster. I could not find, even though people kept referencing that there had been cases of primate to human COVID transmission, I couldn't actually find that study. It is theoretically possible, but it is thought that the risk of you catching COVID from a monkey with COVID, even if the rhesus monkey does indeed have COVID, the risk of you catching COVID from that monkey is pretty low. It's pretty unlikely.
Starting point is 00:25:06 Now, reverse zoonosis, meaning can we humans infect animals with COVID? That is a much bigger threat. We are much more likely to give a monkey COVID than a monkey is to give us COVID. And you're brave to say it. No, it's true. I know. I know. And that's why it's so brave, Sydney.
Starting point is 00:25:28 We are much more of a risk to monkeys. You hear that monkeys? We see it. I didn't mean it as a threat. I don't mean it like a threat. We're owning it. I'm owning that like, yeah, we are the most dangerous primate. We're the most dangerous game.
Starting point is 00:25:44 So, okay, hypothetically possible that if you release dozens of monkeys with COVID into a community, could somebody get COVID? I mean, scientifically, it is possible. It's very low risk, very low risk that you're going to catch COVID for a monkey. Hepatitis C, that's our next one. So very specifically, and I don't know if initially it came from the truck driver, if the truck driver heard it from somebody else, somebody loading the monkeys in, I don't know. But hepatitis C virus was also indicated as one of the things that the monkeys have. no you can't catch hepatitis C from a rhesus monkey but there is a caveat to this i think this is very interesting so i was reading about what can get hepatitis C so humans of course which there is a
Starting point is 00:26:28 treatment that that is a cure now for hepatitis C so i always feel like as a public service i should always mention that yeah we didn't used to now we have them and it can be an eight or 12 week treatment course and we can cure it and that is a breakthrough and talk to your health care providers. Anyway, this is tricky because the only natural reservoirs for hepatitis C virus are humans and chimpanzees, not racist monkeys. Right. Okay. However, it's not like, it is, for a variety of reasons, we don't tend to do research on chimpanzees.
Starting point is 00:27:02 It's not as easy, okay? But we do a lot of research on racist monkeys. So there has been an effort to try and give hepatitis C to rhesus monkeys. Sorry, sorry monkeys. So that we could study it better. And specifically in 2015, there was a study called Hepatitis C virus infects Rhesus macaatoc hepatocytes liver cells in simeonized mice. And basically what researchers were trying to do is put monkey liver cells into mice. Come on.
Starting point is 00:27:34 and infect those liver cells with hepatitis C virus. And they were able to, what they found is that Rhesus monkeys have specific, like their immune system specifically defends them against hepatitis C virus. That's why they don't get it. And they were finding ways to skirt it. Like, they were finding ways around it so that they could in fact. No, that's a bad idea, science.
Starting point is 00:27:56 Why? They can't get it. And so you mix monkeys and mice to see if you can give them hepatitis? It's for a research model. It's a research model. It's maniacal. Listen. Stop doing science.
Starting point is 00:28:10 Listen. That's enough science. I just told you that we have an effective cure for hepatitis C virus now in humans. How do you think we got there, Justin? I don't know, man. I know. I know. What I'm saying is you shouldn't be able to catch hepatitis C from a rhesus monkey that escaped from a lab.
Starting point is 00:28:29 But scientists are trying to fix that. Fantastic. we're any day now we should be getting hepatitis from monkeys thank you science you can from a chimpanzee they're the same thing oh jostin so so i mean generally i would say no like you would not expect a rhesus monkey is infected with hepatitis c because at this point that is only something they are attempting to do in labs and hang in there keep it keep up the good fight y'all no we're a and hey when it all goes terribly sizable sideways and they all turn into zombies.
Starting point is 00:29:06 Don't say we didn't tell you so. Well, it's not like they're going to escape from the truck. We transport them in, Justin. They did. Okay. 28 years later. That's the movie about the zombie monkeys that have mice powers. Now, good.
Starting point is 00:29:20 They could transform into mice with thought. Neat. Now, when I read this... And they can get hepatitis. What's interesting is as I was sitting here debating this with my colleagues when we first heard about this story, and I thought, what could you actually catch from a monkey? I would have thought COVID, yes. I was kind of surprised that it's not a bigger threat.
Starting point is 00:29:38 I would have thought like, well, heapsi. I don't know if monkeys can catch hepsey, but if they can, I figure if they bite you. Like, that seemed reasonable to me. In my mind, before I did any research, herpes seem like the least likely candidate. Because when you think about herpes, and all they said was herpes. And this is difficult to begin with because there's lots of herpes. A lot of herpes. There's a lot of herpes viruses.
Starting point is 00:30:00 So when they say the monkeys have herpes, well, what do you mean by that? so probably when you think of herpes Justin and I do you think of two things yeah what two things do herpes cause um genital sores and mouth sores there you go that's I mean right
Starting point is 00:30:17 that's what most people think of right and what you're what you're referencing is herpes simplex virus one and herpes simplex virus two HSV one and two is easy so those two specific herpes viruses are the ones that most of us think about Herpes virus one, generally speaking, causes the mouth sores.
Starting point is 00:30:35 Herpes virus two can cause the genital sores. There can be some crossover. But generally speaking, this is what you're thinking. Okay. Okay. That is not really what monkeys tend to get, though. And so if you're going to say like the monkeys have herpes, I'm going to wonder what is the most common herpes that a monkey can have. I'm not going to be thinking about herpes virus one and two and a monkey.
Starting point is 00:30:57 And there is a very common. And if you're not thinking about it, then nobody. is. Nobody's thinking about it. So I would suspect if we're playing with this, if we're playing in this space, herpes virus B, herpes B, or just B virus is what it's often called, is a herpes virus and monkeys that is similar to HSV-1, the one that causes cold source, it's similar to what humans get. And so that's the most likely thing that these recess monkeys would have. If they had a herpes virus, that is the most likely thing. And while it does also cause mouth source, it can cause the little ulcers just like HSV-1. It also can cause more serious infections, which is also
Starting point is 00:31:37 true for HSV-1. It can cause things like encephalitis, which is inflammation of the brain. It can do that in monkeys. And herpes B virus can and has done that in humans. There have been multiple cases specifically in research settings, so like scientists in a lab, people who work with rhesus monkeys on a regular basis, veterinary settings, zoo setting, places where you would come in contact with a lot of rhesus monkeys. There have been cases where people have either been bitten by one of these monkeys or in one case, I think some like fluid was splashed into a scientist's eye. And they caught hepatitis B virus from the monkey. And I mean, this don't laugh because it can be a fatal infection. So it's a very serious infection. The idea that I would laugh
Starting point is 00:32:27 to that privately to myself and you would docks me like that is truly untenable. I thought we had a partnership, truly, truly unfathom. We're on camera. I know but there's edits. There's edits. I don't even know if we're going to use this video. We will use this audio where you just absolutely
Starting point is 00:32:43 annihilated me though. I'm sorry. I was just... Well, I was trying to... It's just imagine... I was trying to stop you before you went down a joke path. You should wear glasses. I mean, in the lab. We should wear goggles. Anyway, the point is, I had initially... I actually thought herpes was the least likely, but if we're talking herpes B virus,
Starting point is 00:33:04 that is probably the biggest threat of everything we've discussed in terms of monkey to human transmission because it has indeed happened. I don't want to say frequently. It's not frequently, but it is definitely a danger when you were doing laboratory science with these animals. You could catch herpes from them. Okay. So that's the one that I think is the most realistic.
Starting point is 00:33:23 All of this being said, what is the risk from a population? of infected monkeys that spill out of a truck to the surrounding humans. Unbelievable high. No, pretty low. The chances that they have hepatitis C are pretty much zero unless some weird new science has been done in a lab. And who would be doing that, alpha genesis? Then they're not going to give you hep C because they almost certainly don't have it.
Starting point is 00:33:48 If they did, if we did find a way to give rhesus monkeys hep C, then I guess they could pass it to you if they bet you or if they shared bodily fluids with you. it would be highly unlikely for you to catch COVID from one. I guess if we imagine a scenario where a ton of rhesus monkeys, I mean like dozens of rhesus monkeys at the peak of COVID infection, at their most infectious moment, are surrounding you right in your face and just expelling respiratory droplets at you for,
Starting point is 00:34:18 I mean, we're going to say at least 45 minutes to an hour, right? Yeah. Right at close range, perhaps. But generally speaking, you're probably not going to catch you. COVID from a monkey. And then when it comes to the B virus, it's possible, but you still would need direct contact. You're sure going to have to get pretty close to these monkeys. So I was trying to come up with a number, like how many monkeys could have spilled out of that truck infected with hepatitis C, COVID, and herpes that I would actually be concerned. And I feel like there
Starting point is 00:34:46 is no evidence-based, I mean, it could be infinite. Like there's no- You're saying if you had infinite monkeys and you infected some of them with it if they had infinite amount of time eventually everybody would have herpes i mean if they're biting people yeah i guess the if if we surmise that what that truck driver or what randy johnson or what whoever gave these gentlemen information meant was b virus i would be concerned about enough density of monkeys that they would start attacking people and then yeah that would be my only concern thank you so much for listening to Sawbones, a marital tour of misguided medicine. I was trying to give you one less thing to worry about, right? And you just made a whole
Starting point is 00:35:27 long list of things to add in their place. I cannot emphasize enough, three monkeys are still at large. Do not approach them. Do not approach them. Do not attempt to apprehend the monkeys. You fool. Or chimps, if you can tell the difference. Good on you. Thanks so much for the taxpayers for use their song of Medicines is the intro and outro of our program. And hey, we do lots of different kinds of episodes of sawbones, and we're curious sort of what you guys think, the folks out there in the listening world. If you'd like to weigh in, we'd love to hear from you. There's a link in the description of this episode.
Starting point is 00:36:02 So if you would go check that link, there's a survey there. If you would click it and take that survey, gosh, I'd sure appreciate it. Thank you so much. And, oh, Candle Nights, it's coming up on December 6th. And if you would like to come see the show, you can do that. and I think that you should do that because it's going to be really, really good.
Starting point is 00:36:21 We're going to have skits. We're going to have excitement. We're going to have music. We're going to have a lot more fun. You can get tickets in person if you go to bit.orgive forward slash McElroy Tours is the address. You can get in-person tickets,
Starting point is 00:36:39 but there's also a streaming option. That's going to be out December 19th at 9 p.m. We will be watching that live in the chat if you want to do that. Or you can take a lot of version, 7 p.m. 6th of December at the Keith Albee performing art center. It's going to be huge. It's a beautiful theater, too. The Keith Alby is an old theater here in Huntington.
Starting point is 00:36:57 Yeah, they just refurbished it. It's gorgeous. And come visit Huntington. There's so much great stuff to do here. All the proceeds for this event are going to go to benefit Harmony House, which seeks to end homelessness in our area and support people experiencing homelessness. And it's a wonderful organization. And we're very happy to be supporting. Absolutely.
Starting point is 00:37:15 That's going to do it for us for this week. Until next time, my name is Justin McRoy. I'm Sidney McRoy. And as always, don't drill a hole in your head. supported directly by you.

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