StarTalk Radio - SEASON PREMIERE: A Conversation with Tim Ferriss

Episode Date: January 6, 2020

For our Season 11 premiere, Neil deGrasse Tyson sits down for a one-on-one conversation with author, entrepreneur, and investor Tim Ferriss to explore the writing process, neuroscience and psychedelic...s, marine biology, science fiction, and more. NOTE: StarTalk+ Patrons and All-Access subscribers can watch or listen to this entire episode commercial-free here: https://www.startalkradio.net/show/season-premiere-a-conversation-with-tim-ferriss/ Thanks to this week’s Patrons for supporting us: Saul Flores, Augusta Golian, Alexis Collins, Eric Morales, Solomon Nadaf. Photo Credit: StarTalk. Subscribe to SiriusXM Podcasts+ on Apple Podcasts to listen to new episodes ad-free and a whole week early.

Transcript
Discussion (0)
Starting point is 00:00:00 Hey, StarTalk fans, Neil deGrasse Tyson here, your personal astrophysicist. And as we enter our 11th season, yeah, I said it, yeah, you heard it, 11th season of StarTalk, we've decided to move the posting time of our show from Friday nights at 7 p.m. to Monday afternoons at 3. As it turns out, many of you like to listen to StarTalk when you drive, walk, or take the train, or use any other mode of transportation throughout your universe. So we want to bring you StarTalk right when you need it. Thanks for listening to the StarTalk podcast, and remember to keep looking up.
Starting point is 00:00:39 Welcome to StarTalk, your place in the universe where science and pop culture collide. StarTalk begins right now. Welcome to StarTalk. I'm Neil deGrasse Tyson, your personal astrophysicist. On rare occasions, I sit down to interview someone whose presence is powerful, entertaining, and enlightening all at once. And the conversation that comes out of that encounter is so inspiring or enlivening that we must depart from our usual studio format in exchange for some one-on-one time. On one such occasion, I sat down with entrepreneur, author, and podcaster Tim Ferriss. That interaction led us all at StarTalk
Starting point is 00:01:25 to break format for this special episode. Instead of our usual panel of in-studio expert guests, comedians, and scientists, what follows is my uninterrupted conversation with Tim from start to finish. Tim is best known as an angel investor and advisor for startups. And the most notable startups he's either invested in or
Starting point is 00:01:45 advised are Uber, Twitter, Evernote, and TaskRabbit. He's also the author of several books, including The 4-Hour Workweek, The 4-Hour Chef, and Tools of Titans. For this first part of the conversation, we got to know about Tim and the life that prepared him to become such a prolific author. So let's go to that conversation now. So Tim. Yes, sir. Welcome to StarTalk. Thank you for having me.
Starting point is 00:02:14 So you got a podcast of your own. Wait, let me think. What would be a name for that podcast? You know, one of my friends suggested Tim Tim Talk Talk, which I vetoed, unfortunately for Kevin, but it's called The Tim Ferriss Show. The Tim Ferriss Show, a really popular podcast. And what I like about it most is just how you have, just as a general point of philosophy, you have kind of restructured how people think about how they make themselves what they are. Is that a fair characterization? It's fair. It's fair. I try to do it. It's very personal for me. You can't major in this in school. You cannot. You invented this. I borrowed bits and
Starting point is 00:02:57 pieces from a lot of people. You know, Ben Franklin did something somewhat similar. Oh, excuse me, your friend Ben Franklin. My friend. My good friend Ben. Your Ben go way back. I think the self-experimentation is really drawn from a lot of different influences. Well, let's go back. So when you grew up, were you, did you have any geek underbelly that your friends didn't know? Oh, well, my few friends that I had definitely knew. That meant you had some geek. Definitely knew. If you only had a few friends, that was a geek profile.
Starting point is 00:03:25 I was born premature out here on Long Island and was very, very small. So I was badly bullied as a kid up until about sixth grade. So you were bullied? Why? What were you doing to be bullied? I was bullied because I was the smallest kid in the class.
Starting point is 00:03:40 Smallest kid. That simple. That's it. And had a lot of physical issues, respiratory difficulties because I had lung problems when I was born premature. So you were a sickly kid? I was a weak kid. And that explains a lot of things, including affinity for Dungeons and Dragons, refuge in books. Things you can do alone. Things you can do alone. Things you can do alone. Yeah. Things you can do when other kids go out to recess, so you're not in the middle of the
Starting point is 00:04:07 war zone. Right. And the books largely ended up, because my family very early, my parents did something I thought was very smart, also a necessity, which was they said, we don't have much budget for new bikes or this or that, but we always have budget for books. And that meant that a trip to the bookstore, specifically to the remainder table, was really exciting for my younger brother and for me personally. And I gravitated to marine biology, specifically books on sharks, because out here
Starting point is 00:04:40 on the East End, I had learned very early that Clint, I think it's Clint, who's the crazy shark hunter in Jaws, was based on a guy named Frank Mundus, who lived in Montauk. And I went and met Frank at one point. My mom took me on a field trip to go meet him, and he was a real character. He was a shark hunter, later became a shark conservationist, but he wore an Australian outback hat, had a big hoop earring, painted his toenails, and he was an excellent storyteller. The guy wasn't a scientist, but he catalyzed an interest in marine biology. And so I bought books on sharks, fish, encyclopedias of all different types
Starting point is 00:05:21 when I had the opportunity. And so it's fair to say that I was definitely a nerd. Up until sixth grade. Then that summer I gained... Wait, all that happened before sixth grade? Yeah. Oh, yeah. I'm thinking you're in high school.
Starting point is 00:05:34 No, no, no. Starting college. No, this happened... You're meeting shark hunters. I'm thinking you're older than 12. This started very early. So I remember in third grade sitting on the stoop with this big hardcover book.
Starting point is 00:05:46 I think it was called Fishes of the World. And the substitute teacher at the time told my mom, he shouldn't bring that book to school. He'll destroy it. And she said, you don't know my son. He's not going to destroy that book. So the interest started really, really early. Wow. OK.
Starting point is 00:06:02 So you go from the bullied little kid in the class to someone who's on a mission. Yeah, yeah. But wait, so was the science element of this, that was not an active thought. It was just really cool. It was just really cool, but I ended up later, as I learned more about it, in an interest, a very narrow interest in apex predators like sharks or anything that was dangerous to man basically. So apex, does that mean nothing is a predator to it? Right. So a bear would be apex predator.
Starting point is 00:06:32 Bear would be it. Humans in a way are apex. Humans are the most dangerous apex predator. No one really hunts us except ourselves. That's right. Right. Or sharks. So although human fatalities from sharks are negligible but the the fact that there were
Starting point is 00:06:47 species that still demanded a certain respect from humans was very appealing to me and that then broadened so i went from just looking at sharks to more broadly fish and i want to be a marine biologist for about 15 15 years. That was a real... Just because it was cool. Just because it was cool and I read about Jacques Cousteau and these various people who were diving, gathering samples, running analyses of various types and I just found the entire implementation of what I found in the classroom to be very boring fascinating. It's in the classroom to be very boring, fascinating.
Starting point is 00:07:26 So in the sterile context of a lot of the school classes, it didn't grab my attention, but when it was able to be presented in a story of some type, which is why Frank was so interesting to me, not because he knew science, but because he was good at grabbing attention. Whatever it takes. Whatever it takes. We'll take it. If it gets you there, there we'll take it so that's how it started and uh it certainly i mean continued from there it ended up veering in a sense by the time i got to i mean we're skipping
Starting point is 00:07:56 some stuff but by the time i got to freshman year in college it was neuroscience i was more interested in neuroscience because that was my first major actually, because I have Alzheimer's and Parkinson's on both sides of my family. So I was able to watch the decline of cognition firsthand, and that terrified me. And I also wanted to try to help my parents potentially or their brothers and sisters in some way. Does that also motivate you to make every day count? They're brothers and sisters in some way. Does that also motivate you to make every day count? It does.
Starting point is 00:08:32 It does, and it also motivates me to not focus excessively on lifespan, but rather functional healthspan and looking at how different types of interventions can extend functional healthspan, which you can define across a whole bunch of different parameters, but certainly not forgetting the person's name you're sitting with five minutes into a conversation would be part of that so it certainly is a still is a huge motivator so okay so now it's coming into focus how this life path this arc has come together in the books you've written. You're trying to motivate other people to make the most and best of what they are
Starting point is 00:09:11 and their time and their investments in who and what they can be. I got the list of books here. I mean, one of these showed up in my office, actually. Did you send it to my office? I did not. It was the four-hour body. Four-hour body. Was that the one? not. It was the four-hour body. Four-hour body.
Starting point is 00:09:25 Was that the one? No, no, the four-hour chef. Four-hour chef. That would have been 2012. I got the dates here if you don't remember. 2012. Yeah, 2012. No, it's like these are big books.
Starting point is 00:09:34 They are big books. They are. They're choose-your-own-adventure books. They're buffets. So very nonlinear in that way. But yeah, they're big. They're big. Let's just spend a minute on each book here.
Starting point is 00:09:44 Sure. Okay, so the Four-Hour Workweek. Where were you trying to go with that? That book, that was an accidental book in the sense that I... Yeah, everyone writes books by accident. Well, it was accidental in the sense that after my senior thesis in college, I...
Starting point is 00:10:00 On? On native English speaker acquisition of Chinese and Japanese characters. So I was looking at the semantic and phonetic, both pathways and tools that a native English speaker could use to accelerate the acquisition of East Asian writing systems. And how many majors did you have? I had one. So I started in neuroscience. We can talk about why I made the shift,
Starting point is 00:10:26 but I was in psychology, technically, with a specialization in neuro, and then went to the East Asian Studies Department with a concentration in Japanese. Okay. The four-hour work week came about because starting in 2013, that's not right, that's when I stopped.
Starting point is 00:10:43 Starting in around 2003, I was invited back by an incredible professor I had named Professor Xiao, spelled Z-S-C-H-A-U. Amazing polymath of a guy. We could talk about him. How many polymaths anymore? That's like an old world thing. If you can find one in modern times, that's a fascinating fact. He was a competitive figure skater, a congressman, took a couple of companies public, and was a revered professor at Harvard Business School, among other places.
Starting point is 00:11:10 Also taught computer science at Stanford before that. And I had been invited back to his class to guest lecture twice a year to talk about building bootstrap startups as opposed to venture-backed, outside-financed startups. And the notes from that class, as my life changed from, say, 2003, where I was on the verge of burnout because I was working on my own company,
Starting point is 00:11:38 to 2005, 2006, as my life changed, the content of the course or the lecture changed. And it turned... The lecture you delivered. That's right. So it started off... So these are windows into you. Absolutely.
Starting point is 00:11:51 Yeah, for sure. Every book that I've written has been a book I couldn't find for myself. And... I love that. There's 30 million books in the world, and there's one that hasn't been written yet, and I got to write it. Yeah, if I needed it, I could find it. That's kind of audacious, you know.
Starting point is 00:12:07 What was that? That's kind of audacious. It's audacious. It's not out there. I'm right there. It's audacious and selfish. It's self-interested. Bodacious.
Starting point is 00:12:16 Bodacious. There we go. Let's go with bodacious. That's better. And at least if you're writing a book that you yourself would have needed, you know you have a guaranteed readership of one. Plus your mom. Plus your mom. And so the four-hour workweek was really the collection of notes from those guest lectures assembled into a book, which was recommended by a few of the students in the class and then by a friend of mine who was an author. But after the senior thesis,
Starting point is 00:12:41 I had vowed not to write anything longer than an email after that because it crushed me. I had a very hard time with the thesis. A very, very difficult time to the extent that I took a year away from college actually. Can I give a personal reflection on that? Yeah. So I've written two theses, a master's and a PhD thesis, and I have some books. Each one of those was like giving birth. Not that I know what giving birth is like, but if I were to imagine it, it's like,
Starting point is 00:13:08 this is a piece of me coming out. There it is. Okay, I got to just go home now. I got to not do anything for like three years. I have to regenerate, regrow myself, my mind, body, soul. Then we can have another conversation. Definitely. And it's also like childbirth in the sense that
Starting point is 00:13:25 at least many of the women I know who have given birth, they're like, all right, not doing that again. And then a year and a half, two years later, here we are again. I think the forget chain has to show up, otherwise none of us are going to be here. First and last. The human species would have been gone long ago without that little forget. Yeah, so you've written a lot.
Starting point is 00:13:45 I mean, you've written, you've put together a lot of writing. You've been very prolific. And it takes... Yeah, but this is, it's more traditional. It's like I'm an expert on a subject. Yeah. And then there's some new stuff in the subject, so I write about it. You're creating an awareness that people didn't even know they didn't have.
Starting point is 00:14:03 Right. Is that a fair characterization? It's totally fair. And if you look at the 4-Hour Workweek, which is basically an entrepreneurial exploration of hidden assumptions, governing behavior, which was influenced also by a bunch of the professors
Starting point is 00:14:16 I had, like Bart Hobel, who studied, among other things, sugar addiction, published a lot of seminal papers that ended up creating almost a sub-specialization within psychology. It's really about hidden assumptions. So the four-hour body was the same. What are the hidden assumptions that are limiting the options? Four-hour body, so we just shifted books. Four-hour body, 2010. 2010. And just to explain the whole four-hour thing, because it's a blessing and a curse,
Starting point is 00:14:43 and it sounds like an infomercial product, I'll cover that. It so does. It does. Just let me be up up front with you there. It does. So I had a number of titles for the book, the first book, which was turned down by 26 publishers, by the way. Didn't it make a great folder? It does.
Starting point is 00:15:01 Yeah, it does. Some of them were so violent, unnecessarily aggressive. It's like John Grisham has a folder like that. All his early turn downs. They were fantastic. Didn't feel fantastic at the time, but in retrospect, good to look at. I had about half a dozen or a dozen titles and prospective subtitles. And the publisher and I disagreed on the preferred titles. And instead of having a really emotional debate, I said, give me a week, let me test it. I'm very good at testing.
Starting point is 00:15:36 And went on to Google AdWords and created, or I should say bought, domains for these various book titles, created advertisements that had the book titles as the headline, the subtitles as the ad text, and at least at the time, I haven't used Google AdWords in a long time, but it would mix and match and do the multivariate testing for you. And then I would look at the click-through rate,
Starting point is 00:16:02 and if people clicked, it just took them to an under-construction page because I was not testing the content of the page. I was testing the attention advantage of different combinations of titles and subtitles. And at the time, I was spending about two hours a week managing the business that I'd created, which was later sold. The two hours seemed too unrealistic to the publisher, and I was like, four hours?
Starting point is 00:16:26 And they're like, sure, four hours sounds great. So I tested that, and the combination of that and the subtitle performed many standard deviations better than above everything else. And that's how I ended up choosing the title and the subtitle. You know, that's disappointing, because we all wanted you to say, well, it was a spark of genius
Starting point is 00:16:45 that came to me one night over a beer. No, no, no. You actually applied scientific principles. Yeah, it was a few hundred bucks and what it did is it overrode all the sparks of stupidity
Starting point is 00:16:59 that had generated a lot of bad ideas. That's what it was. When in doubt, test it. That's right. That's what that comes down what it was. When in doubt, test it. That's right. That's what that comes down to. Yeah, when in doubt, test it. Absolutely.
Starting point is 00:17:09 And so, you all came out just recently. I haven't read that. So what's that about? Charmed Mentors is really a collection of profiles of 130 or so what I would consider
Starting point is 00:17:23 world-class performers. People who are at the top of their respective fields. That could be sports, it could be poker, it could be all of those things. Business, certainly. Singularly achieving people. Singularly achieving people. And what distinguishes them.
Starting point is 00:17:39 And the way that I was able to discern what distinguishes them is by asking them all the same 10 or so questions. And what I enjoyed about that book, aside from the fact that it was nice to actually have 130 people write the book for me, which I'm not going to do for every book, but the first three brutalized me. So I decided to take a little breather on that and to see if it would work, and it did.
Starting point is 00:18:09 What's nice about that is that you ask these people questions. What do you do when you feel overwhelmed or distracted? What have you become better at saying no to over the last five years? How do you say no? The no is really important. People don't realize how many no's are floating around out there. Yeah, it's really important. It's really important. And there are favorite failures, for instance. What is your favorite failure or a favorite failure, meaning a failure that
Starting point is 00:18:35 in some fashion set you up for a larger success later. And the profiles are organized in such a way that you can spot patterns because you'll see commonalities across some of those answers, which means, and this has certainly been my experience interviewing people on the podcast, that top performers in distinct fields often share more in common than they do with, say, the C players in their own field. There are a lot of shared characteristics So that's travel mentors. So that would be that would argue strongly for
Starting point is 00:19:10 Training people in school to have certain attributes without specific reference to a subject. Yes Then you set them loose on whatever subject interests them and then they they didn't know how to tackle it how to find it How to know ascend to the top. Totally. Agreed. Completely agreed. And the third book, The 4-Hour Chef, is confusingly not only about food. It's about a framework for learning. It's a series of steps that one can use to tackle different subjects or skills. It could be facts and figures, declarative knowledge.
Starting point is 00:19:47 It could also be procedural. It could be some type of physical skill. And I do think it's really important not to convince someone that their ability to learn is somehow siloed in a single domain. That's, I think, not just paralyzing in some respects, but it creates blind spots and is dangerous. So that's a reason also that one of my most influential teachers was someone I never met who is Richard Feynman.
Starting point is 00:20:14 So I'm not a scientist, I'm not a physicist, but going to Princeton also. As an undergraduate. As an undergraduate. The interest began with, surely you're joking, Mr. Feynman. As it did with the best-selling book of his. Incredible book. Not a big book either. No, it's not.
Starting point is 00:20:30 Thinner than your books, by the way. By far. Just let the record show. By far, yes. More quality than quality. For sure. Fat books, surely you're joking, Mr. Feynman, skinny books. And what appealed to me so much about Feynman,
Starting point is 00:20:46 and in the last couple of years, I don't do this kind of stuff ever, but I actually bought at auction a collection of his encyclopedias. That he owned? That he owned and bought when he was 40. So I'm 42 right now. And the fact that he bought these encyclopedias at 40 with his track record and accomplishments
Starting point is 00:21:01 up to that point was inspiring to me that he would he would still have not just these references but he would memorize large parts of the Encyclopedia Britannica in any case so Feynman a few have his encyclopedic set that's right from his that he does from his from his office okay and this just came up for auction it it came up very unusually for auction from a private collection almost none of his papers or belongings have ever gone up for auction and there are a few friends of mine who like me are obsessed with a handful of people including Feynman. One friend has actually given his his one of his sons the middle name Feynman just to give you an idea and he brought it to
Starting point is 00:21:53 my attention. He said just in case you haven't seen it this is coming up. I'm afraid to ask you if you have kids what you named them. Probably not. That's a little scary at this point in this conversation. I'll leave. I don't want I don't. right so no no fine men's yet but the fact that he took this this curiosity was more the curiosity than the accomplishments that appealed to me and applied it to safe cracking applied it to cryptography applied it to music the and this ties into your question about teaching people to learn, or I should say your comment rather, of giving people a toolkit and at the very least convincing them that there are certain principles that apply in a cross-disciplinary way, I think is super important. And so Feynman for me has always been a reminder to take the curiosity that I might be focusing in one place
Starting point is 00:22:46 and try to take whatever I learn and see if it applies elsewhere. And that's certainly the case with a lot of the books. It's taking something that seems to work in one place and trying to apply it in another and seeing what happens. We've got to wrap up this segment of StarTalk. Coming up, more of my one-on-one conversation with entrepreneur Tim Ferriss see you in a moment Welcome back to StarTalk. We've been following my one-on-one conversation
Starting point is 00:23:37 with entrepreneur Tim Ferriss. Let's get back to it. So, my crack team of researchers tell me that you've been into science fiction. So what prompted that? I've been interested and have loved science fiction for a really long time. Fantasy as well, but science fiction included. And it started with a recommendation from my mom, who said that I should read A Stranger in a Strange Land by Robert Heinlein. And that really
Starting point is 00:24:08 captured my imagination. And I felt like there was a lot you could learn from it. As I also feel about a lot of the science fiction I've read since. Dune, certainly. If you want to learn about leadership, I think Dune is a fantastic book. You don't have to read non-fiction necessarily. Worldbuilding, I mean that's a great example of world building. So did science fiction, not to put words in your mouth, but did science fiction enable you to think about possible worlds that don't currently exist, but with some energy and investment and some wisdom, you might be able to get there?
Starting point is 00:24:42 And so in life, a possible world could just be a possible career path that was not otherwise visible. Definitely. That's absolutely true. And I think it gives you a lens through which to look at the present that allows you to see possibilities that may have been invisible to you before. And certainly, a lot of the, if you want to call them predictions, descriptions in science fiction have found a home. Whether that's a self-fulfilling prophecy or not is a separate question.
Starting point is 00:25:15 A fun question, too. It's a fun question, yeah. It's sort of the art imitates life, life imitates art conversation. But it allowed me to look at things differently. conversation, but it allowed me to look at things differently. And I enjoy finding prompts and tools that allow or force me to look at things differently. And that's taking the form of science fiction. You can do a lot of experiments with sensory substitution and all sorts of weird things that we could talk about that definitely force you to perceive the world differently. We're getting there.
Starting point is 00:25:46 Yeah. And the science fiction and love of science fiction has continued. So more recently, after the classics, Dune and so on, you have people like Ted Chiang, who has an amazing collection of short stories. I think it's called Stories of Your Life and Other Stories. But one of his short stories, Story of Your Life, was adapted and turned into a film, Arrival,
Starting point is 00:26:11 which is an incredible film that gets into language and all sorts of topics that I appreciate. And it's not every film where a linguist is the star. It's the star. And it's so... By the way, just to be clear, there's a version,
Starting point is 00:26:30 there's a movie with that title from the 1990s starring Charlie Sheen. Yes. And then there's one in the 2010s, Arrival.
Starting point is 00:26:40 Mm-hmm. Yeah. Which is an incredible story and an incredible film because it uses the allure and the sexiness of science fiction to delve into topics and questions that might
Starting point is 00:26:54 otherwise be very sterile. Like how does language affect your thinking? How does language if at all affect your perception of time? And this came about because of our attempt to communicate with aliens. With aliens. of our attempt to communicate with aliens. With aliens. That they were trying to communicate with us.
Starting point is 00:27:07 Who communicate with us through basically these Rorschach inkblot pictograms. And as someone who studied Japanese and Chinese and so on as an undergraduate, specifically the writing systems, I just loved that. And it's a Trojan horse for getting people interested in subjects that might otherwise be too sterile. So that's another aspect. Trojan horse in a good way. In a great way. In a great way, yeah. Okay. Most references to Trojan horses, especially with viruses, computer viruses, are negative.
Starting point is 00:27:39 This is a positive smuggling. Get in the door and then you explore the new city. You just... That's right. This is benevolent idea smuggling. Yes, yes. What's your fascination with psychedelics? Is this, you have a background interest in neuroscience. I do, yeah.
Starting point is 00:27:57 So is there a connection there? There is. There is a connection. And it's also very personal, and I can talk about that. But I'll talk about the neuroscience first. The interest in neuroscience, that was actually one of the contributing factors for also looking at psychology first. And when I was at Princeton, aside from Bart Hobel and some other professors who had an impact on me, I was attracted to the work of Professor Barry Jacobs. attracted to the work of Professor Barry Jacobs. And Barry Jacobs focused on, among other things,
Starting point is 00:28:33 monoamine neurotransmitters, such as serotonin. Looked a lot at serotonin in sleep. He also... Chemistry of the mind. Chemistry of the mind. And he had looked also quite closely at hallucinogens and their impact on various types of mental function. I'm betting he didn't teach a class in that. He did not. Okay, I'm just thinking. I don't know for sure. Just thinking.
Starting point is 00:28:52 He did not, but I wrote one of my junior papers on the physiological similarities, so I guess you could call it biological similarities, at least as we measured them at the time, between LSD or LSD-25 and REM sleep. It turns out there actually, there's a lot of common ground, which is really, really fascinating and could explain some of the later findings related to not just LSD, but a lot of these serotonin 2A agonists, which a lot of these psychedelics are, meaning that they activate or bind to these serotonin 2A receptors.
Starting point is 00:29:33 There are many other receptors that are impacted. But it's one thing to have an academic interest in hallucinogenics. Another thing, if you're sort of a life coach, that implies there's some practicality that you can bring to bear. Yeah, and I definitely view myself more as a human guinea pig who reports the findings more than a life coach. But the personal reason for looking so closely at psychedelics
Starting point is 00:30:02 and more recently taking almost all the energy and capital I was applying to startups and applying it to science is that my family, aside from having Alzheimer's and Parkinson's on both sides, also has severe depression on both sides, whether it's chronic treatment-resistant or bipolar. And that is something that I struggled with for many decades. And it's only really... Well, you're not that many decades old.
Starting point is 00:30:34 That's true. I mean, 42. But since I was... Since you're 42, many decades. Many decades. Handful of decades. I can talk about many decades. You can't. Handful of decades. Thank you. Several decades. One handful of decades. I can talk about many decades. You can't. Handful of decades.
Starting point is 00:30:45 Thank you. Several decades. One handful of decades. I've suffered a major depressive episode, I would say, at least every six months. And in the last five or six years, with many different interventions that we can talk about, not just pharmacological, have not experienced a single extended depressive episode. That's very atypical.
Starting point is 00:31:11 And that's the personal driver behind looking at some of these compounds that in the literature and certainly anecdotally, whether it's at a therapeutic dose or a large dose or a microdose, seem to impart lasting anti-anxiety, so anxiolytic and antidepressive properties. And this has been looked at at places like Johns Hopkins and others. What makes it so compelling to me is that you have many what would be considered intractable, often intractable psychiatric conditions,
Starting point is 00:31:47 eating disorders like anorexia, highest mortality rate of any psychiatric disorder, addiction of various types, nicotine, opiates, obsessive compulsive disorder, depression, chronic anxiety, which may actually all be variations of the same thing when you look at functional MRIs and so on. It's specifically something called the default mode network. So personally it was the depression.
Starting point is 00:32:09 So functional MRIs, you actively monitor the brain activity while you know what the person is thinking. That's right. So you can track it. That's exactly right. Or after you've administered them a given drug. administered them a given drug. And the psychedelic scientific exploration was suspended effectively late 60s, early 70s onward
Starting point is 00:32:35 when the Nixon administration placed many of the classic psychedelics in Schedule I for political and not scientific reasons. Schedule I meaning high potential for abuse, no known medical application. Heroin. Heroin, exactly, with corresponding penalties. So that's...
Starting point is 00:32:54 Jail. Jail. Yeah, the legal side effects. Corresponding penalties. Jail. Yeah, the legal side effects are very, very stiff. So that's the personal... So you think that tabled what could have been
Starting point is 00:33:05 more exploratory research that could have helped people? Is that what you're suggesting? Oh, absolutely. 100%. Not just for therapeutic applications, because you find that in some instances, let's take nicotine addiction as an example. Matt Johnson, Dr. Matthew Johnson at Hopkins has looked very closely at nicotine addiction. And with, I want to say, two or three administrations of psilocybin, which is thought to be the most active molecule from a psychedelic perspective in magic mushrooms, so-called magic mushrooms, psilocybin mushrooms. You can synthesize psilocybin, administer it two or three times with psychotherapy. This is not a daily drug. And six months later, I want to say six months later in this study, which people can look up, there was around an 80% abstinence rate, six-month post.
Starting point is 00:34:00 Compare that to the current best intervention or drug available, which is going to be taken constantly, and that might be high 20s or low 30s. So it's some. Yeah, it's some. It gives people some hope, but not statistically strong hope. Yeah, you're looking at a huge improvement. And with the antidepressive effects in many subjects can also last on the order of months.
Starting point is 00:34:26 That's from one or two administrations. This is not a daily drug. So my interest in this is in part hopefully funding science that helps with therapeutic applications with what people consider unsolvable psychiatric issues. Because we've had all these breakthroughs in cardiology, immunology, and so on. Well, brain's a tough nut to crack. It is is and psychiatry literally and yeah so there's really been very little aside from SSRIs and more recently ketamine that could be considered breakthroughs of sorts and and they don't necessarily in the case of SSRIs work for everyone and not for necessarily a long period of time. And a more fundamental exploration of consciousness.
Starting point is 00:35:10 So there's the therapeutic application and then there's the exploration of consciousness itself, which I find equally, certainly equally interesting. We've got to close out this part of our show now, but stick around for our final segment when we wrap up my conversation with entrepreneur tim ferris we'll be right back We'd like to give a Patreon shout-out to the following Patreon patrons, Eric Morales and Solomon Nadav. Thanks, guys, for helping us as we make our way across the cosmos.
Starting point is 00:35:54 And if you would like to get your own Patreon shout-out, make sure that you go to patreon.com slash startalkrad Radio and support us. Welcome back to StarTalk. We've been following my conversation with Tim Ferriss. Let's get back to that conversation now. Tell me more about life hacking. Just, what does that mean? Life hacking... My life is fine. Why do I want to hack it?
Starting point is 00:36:34 Yeah, you may not have to. You may not have to. Life hacking... Okay, who is ripe to get to be life hacked? What kind of profile? What's the profile? If someone who feels that they are not optimizing efficiency in one or more areas of their life. So if there are symptoms of overwhelm, a... Why is efficiency the measure of what is good?
Starting point is 00:37:00 It's not. It's not. But that's a symptom that can then lead to applying certain toolkit i don't use the word life hack much but it's a term that is broadly used to represent any type of tool or shortcut that allows you to achieve a result or automate certain things also achieving a result much like computer hackers okay okay so all, so it's not that I live a perfectly efficient life. It's that there's certain tasks that I could have gotten done a little faster, better, simpler, and the life hack helps that, and that gives me time to do other things. Is that a fair characterization? That's totally fine.
Starting point is 00:37:36 Yeah, I think that's fair. And hack is really a versatile word, and I'll give you an example. It's a versatile word, and I'll give you an example. First, just to set the context, like you said, efficiency, you can do a lot of stupid things quickly as well. That's right. That does not make... That doesn't make you wise. It doesn't make you wise, and it doesn't make those things important.
Starting point is 00:37:56 Right. So I do think that what you do is more important than how you do anything. You need to choose your targets first and then apply a good process. anything. You need to choose your targets first and then apply a good process. But a life hack or a hack could be applied to language learning. Anything that has a lot of assumptions and baggage and decades and decades of the same teaching or the same approach to learning is generally ripe for some type of assumption testing and that's where you find approaches that may be much much more effective interesting but why not admit that maybe because it's been done this way forever that is the best way someone already
Starting point is 00:38:35 hacked it a hundred times and then no more hacks left for you that might be true but that's and that is a hypothesis worth disproving right it's like if Karl Popper like science is falsification, all right, great, let's try to falsify. Because the worst case scenario is we figure out, okay, guess what? This painful rote approach that we have is the best of the best of breed.
Starting point is 00:38:56 Sorry, pal. There's no fast shortcut through this. So that relates to meta-learning? It does relate to meta-learning. In what way? Well, meta-learning is a systematic way of approaching learning a new skill or subject. Does it assume you don't know anything about it at first? It does.
Starting point is 00:39:19 There's a colleague of mine. He said he was never good at swimming. And I said, well, how do you know? Well, the first time I tried, I flailed in the water, and everyone passed me in the race, so I just gave up. So that was his measure that he would never be good in swimming. But I was not convinced of that. Oh, sure.
Starting point is 00:39:36 Well, that's not much of a data set, is it? But it's not a data set. It's like a really crappy data set. We're assuming that your first time out, if you don't shine, then you'll never be great later on. And I think that a lot of people who could continue to ascend if their interest and ambition directs them.
Starting point is 00:39:54 So you have ways of making this happen. I do. And I'll give you a very concrete example because you mentioned swimming. So I couldn't swim, meaning from to one end of the pool and back, let's just define it that way, until I was in my early 30s.
Starting point is 00:40:10 I grew up by the ocean, and I had a huge fear of drowning. Of sharks. Of sharks. Not so much of sharks, but of drowning. I had a very acute fear of drowning. And anxiety. And anxiety about it. And I did not have confidence in my ability to swim.
Starting point is 00:40:27 And it looks bad if you're 30 years old and you've got those little... Yeah, the floaties on your arm. The floaties on your arm. You're not going to be... You're not getting a date that night. It's not happening. Ladies, it's not the best approach.
Starting point is 00:40:39 And what changed that is a friend introduced me to a method of swimming that was very counterintuitive called total immersion. And what total immersion did is what I also do in other fields. So there was a kinship. And that is they test assumptions. Again, tactics apply to more than one field. That's right.
Starting point is 00:40:58 And one of the approaches that you would take, and this is a little out of order, but one of the pieces of meta-learning, if you are a novice or if you're an intermediate trying to get to advanced, or advanced trying to get to super advanced, is to ask what the failure points might be. What are the factors that could cause me to quit, specifically? And in my case, what were the things I disliked
Starting point is 00:41:20 about the lessons I had taken? Because I had tried lessons, not just once, but many times. Because I had a friend hold me accountable we assigned each other new year's resolutions and mine was to do a one kilometer race swimming swimming and I couldn't do one one pool length full length and uh total immersion does this with swimming so what are some of the failure points kicking so I had been taught when I took lessons, here's a kickboard, kick your way, we're going to warm up. And I would flame out before I, I would flame out and be completely exhausted within five minutes of starting. And that was the end of the lesson. I couldn't even
Starting point is 00:41:53 continue with the technical training, right? So they put conditioning slash warmup before technique. Number two, fear of drowning. How do you remove fear of drowning? Don't practice in deep water, practice in a shallow end of a pool. All right, what else? Breathing. How many people do you know, I know tons, who can kind of swim around, but they have no semblance of rhythm with any kind of breathing? Almost everyone. Breathing. Let's take breathing out. All right, now if you remove those things, how might you practice? You could practice by kicking off a wall in shallow water and practicing gliding so that you develop the proper fuselage position right and left and begin to understand what? Hydrodynamics. Because when most people swim, they keep their heads up
Starting point is 00:42:35 and 90% of their energy is going into keeping their heads up and less than 10% is actually propelling them forward. So this would be an example of how you can... Okay, but that means every next thing requires that, a kind of analysis unique to that subject. No, it doesn't. Well, it sounds like it, because I want to learn how to play the piano.
Starting point is 00:42:56 Okay. I had lessons when I was 13, and then I stopped. Yeah. But I got a piano at home, and I stare it down every day. It's like, I tiptoe past it. The undone homework. Yeah, the undone homework.
Starting point is 00:43:11 And jumping into that is not about aquadynamics. It's not, but let me back up and zoom out and just give you the framework, because I think it'll be helpful. So the framework for meta-learning that I use, it's not the only way, but it does apply to a lot, is DIS as an acronym, D-S-S-S, all right? So D and three S's.
Starting point is 00:43:32 The first step, and I can apply this to, you can easily apply this to music, I've seen it applied to music or to language, for instance. Deconstruction is taking this thing, learn the piano, right? Or learn Japanese and breaking it into constituent parts. What are the pieces, right? Body posture, scales. In the case of language, you could have vocabulary, grammar, oral fluency, writing. You can start to piece it out. Deconstruction. Then the next step is selection, which is when you do an 80 20 analysis of the
Starting point is 00:44:06 material they've broken out looking for the the 20 of say exercises or practices that will produce 80 of what your desired outcome is this is very easy to do in i would imagine music and certainly in language because you can look at word frequency lists. So it's not 400 words in the English language. I love word frequency lists. It's not 400,000 words. It's like 1,500 words. Most communication is just a few hundred words. And then you have, this is the part that we were just talking about,
Starting point is 00:44:38 is sequencing, putting things in a logical progression. That is the secret sauce, I think, that gets ignored by a lot of people who are even very good at what they do, is the sequencing. And the last one, and this might help with the undone homework and the piano, is stakes.
Starting point is 00:44:56 So setting up consequences so that you have a reward and or a punishment that are more rewarding or more uncomfortable than sitting down and practicing at the piano. That's the lab rat factor. Or, or, yeah. If I put a little cookie on the side. Yeah, it could be a cookie.
Starting point is 00:45:13 It could be a cookie. I'll give you a great example. The one way you could set up stakes is by putting together, let's just say it's for weight loss. You could put together a betting pool where you have five friends and say, all right, we're just going to put in a hundred bucks and by the end of the quarter we're going to do before and afters we're gonna measure our body fat percentage whoever drops percentage wise the most
Starting point is 00:45:35 gets the pot in that case you have a reward and you have the loss aversion which is very very powerful as a motivator and well if you're competitive yeah if you're competitive so yeah. If you're competitive. So that is why the stakes is something that you customize. And there are tools out there, like Stick is a nice one, S-T-I-C-K-K.com. We can talk about that, where you pick an anti-charity that your money goes to if you don't hit your goal.
Starting point is 00:46:00 A charity you dislike. It never occurred to me that surely there are opposite charities out there. That's pretty scary. Yeah, for sure. Do you think a charity, oh, that's the right thing that we all agreed to do. You've got another one that's trying to not make that happen. Yeah, totally. And there are different ways to approach this question of motivation and behavioral change,
Starting point is 00:46:20 which is what I've done kind of from day one. But the point being that I recall hearing a story of this kind of stage, let's call it life coach, who said he could cure any kind of phobia. And he had this woman come up. She said, I've never been able to get past climbing ladders or stairs. And he said, all right, here's a ladder. And he did some whiz-bang voodoo. And she climbed the ladder and came down. And he's like, and you see, ladies and gentlemen, da-da-da.
Starting point is 00:46:51 And he started giving himself all this credit. And she said, yeah, you know, I'm really happy because my husband told me if I climbed the ladder, he'd give me $100. Well, maybe it's not the stage magician. Maybe it's the incentive. So that's the framework. And it does work for a lot. I noticed that one of the friends of StarTalk you had
Starting point is 00:47:13 in your interview book, Jan Eleven. Yeah. And so, would she or might she have been your token astrophysicist in that book? We all need a token astrophysicist. Specifically, she's a cosmologist. Everyone should have a cosmology friend. Everybody should have a cosmology friend.
Starting point is 00:47:33 She is a great, not just thinker, but communicator. And I really feel... She thinks about how she communicates. She does. Right, so it comes out, it's like, wow, I've just been taught by someone who's really thought this through. Yeah, and we met through Maria Popova, who runs a site called Brain Pickings. And she is also someone who thinks about thinking and thinks about communicating important concepts and does a great job of it. thinks about thinking and thinks about communicating important concepts and does a great job of it.
Starting point is 00:48:11 And I think that part of the reason I admire both of them so much is they recognize that knowledge held is one thing, knowledge shared, and then knowledge shared, which is actionable in some way, are three different things. And they do a really great job, I think, of explaining potentially complex subjects very simply. You know what frustrates me? People who read a lot, but then don't share anything that they learned. Yeah. Like, people read four books a day, and they just sit there. Can you share something? Yeah, yeah, share.
Starting point is 00:48:41 Did you learn something? Is there some wisdom? Is there some? Not just like reading. And so I think, I don't know, do I Did you learn something? Is there some wisdom? Is there some? Not just like reading. Yeah. And so I think, I don't know, do I get to say
Starting point is 00:48:47 that that's selfish of them? I think it's maybe selfish and also delusional in the sense that if you can't teach something, I don't think you understand it. Ooh. Yeah, that's a good one.
Starting point is 00:48:59 Yeah. People have said that. So if you want to test your retention and understanding of that book you just read, let's see you try to explain it to somebody. Right, right.
Starting point is 00:49:08 Then we'll know. Then we'll know. Then we'll know. Yeah, absolutely. It's time to wrap up this episode of StarTalk. I hope you enjoyed listening to this conversation with the one and only Tim Ferriss. If any of his contagious energy, passion, and curiosity emanated through this podcast, the world will be better off for it.
Starting point is 00:49:29 I think there's not enough people like Tim Ferriss in the world. And you know that because he's so popular. And yet his message, on some level, is so simple. It's how to make the most of who and what you are. How to derive happiness from it, how to bring fulfillment to your life, your work, your home. Imagine if we all just thought that way and felt that way, how different this world would be.
Starting point is 00:49:59 You've been listening to StarTalk Radio. I've been your host, Neil deGrasse Tyson, your personal astrophysicist. And as always, I bid you to keep looking up.

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