Stuff You Should Know - How Pollen Works

Episode Date: July 2, 2013

For about 375 million years, plants have been using pollen (aka plant sperm) to propagate their species. And the technique has stuck around because it works. Join Chuck and Josh for a cozy look at the... ins and outs of plant reproduction. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Transcript
Discussion (0)
Starting point is 00:00:01 They're breaking in! From M. Night Shyamalan. Your family must sacrifice one of the three of you to prevent the apocalypse. We're not sacrificing anyone. This February. The last three times. For every new you give us, billions will perish.
Starting point is 00:00:16 This is delusional! Save your family. I'm on my family side. Or save humanity. Make a choice. Now get the cabin. Only in theaters February 3rd. We're at our under 17 at a middle without parent.
Starting point is 00:00:30 This message is brought to you by Discover. Did you know you could reduce the number of unwanted calls and emails with online privacy protection, the latest innovation from Discover? Discover will help regularly remove your personal info, like your name and address, from 10 popular people search websites that could sell your data. And they'll do it for free. Activate it in the Discover app. See terms and learn more at discover.com slash online privacy protection.
Starting point is 00:00:56 Welcome to Stuff You Should Know from house.works.com Hey and welcome to the podcast. I'm Josh Clark and there's Charles W. Chuck Bryant. And that means it's time for Stuff You Should Know. The itchy, screezy, skeezy, scratchy edition. Not skeezy. No. That's not.
Starting point is 00:01:20 The itchy, scratchy, sneezey edition. That's what I meant. There you go. It's funny how you can mix words together and come up with other words you didn't mean to say. Jerry's eyes are itching. Yeah. Well, we should say we're just talking about the pollen count here in Atlanta. That's pretty much all we ever talk about ever.
Starting point is 00:01:37 Sure. When the camera's not on or the mics aren't recording. That and Coca-Cola. Oh, you know how everyone comes to Atlanta and they're like, oh, every street's named Peachtree. Oh, yeah. Let's go drink a Coke. Because those are the only two things we've ever had.
Starting point is 00:01:51 Exactly. All right. Sorry. So you want to talk about pollen some more? Yeah. It's low right now in Atlanta. 39. That's moderate.
Starting point is 00:02:00 Yeah. Well, low for us. Right. But according to the pollen scale, the scale that they used to count pollen and then designate it somewhere along the pollen spectrum, 39 is considered moderate. Not even low. Moderate. When it's really bad here in Georgia, it gets to about 9,000.
Starting point is 00:02:18 Yeah. In the few weeks that the streets run yellow when it rains with yellow water. Yeah. Looks like pee. Yeah. Your car's totally covered in it. You're covered in it. It's just everywhere.
Starting point is 00:02:31 Everywhere. Yeah. But now we're about to tell everybody. We're basically going to turn everybody into a palinologist. Yeah. To an extent. You should be a big fan after this. An amateur palinologist.
Starting point is 00:02:41 I think about a third of all the plants and vegetables and fruits and vegetables we eat are here, thanks to pollen. If you like eating food, it doesn't come in a box. Thank you, pollen. Is it just a third that pollinate or a third that are just angiosperms or gymnosperms? A third that pollinate. Wow. Yeah.
Starting point is 00:03:04 What's up with the other two thirds? I don't know. Well, you know, bananas. They're clones of one another. There you go. There's one. There's the one. I think 1,000 varieties of bananas, and thanks, by the way, to Damn Interesting for this information.
Starting point is 00:03:18 But there's like 1,000 varieties or species of bananas, but each one, like if you eat like a type of just one of those species of bananas, you're eating an exact clone of every other banana in that species because many thousands of years ago, humans just stumbled upon the banana, which is a hybrid of two basically inedible fruits that came together to form the delicious banana, but made them sterile. All banana plants are sterile, and the only way that they're allowed to propagate is by human hand. They're delicious.
Starting point is 00:03:49 I did a Don't Be Dumb about that. Oh, yeah? Yeah. Well, you just did it again. Yeah. You can check out Don't Be Dumbs on our website, StuffYouShouldKnow.com. Wow. All right.
Starting point is 00:03:59 Anyway, pollen. Yes. It's been around for a while. I know in our bee podcast, we talked about how bees and pollen kind of emerged side by side 100 million years ago. Some say it co-evolved. Right. But pollen actually goes further back than that.
Starting point is 00:04:13 Yeah. In this article, it says about 375 million years ago is when the plants started getting clever and spreading their seed literally using pollen. That's right. Different techniques. And I think that the gymnosperms were first. You think so? I believe so.
Starting point is 00:04:29 Yeah. And the author of the article here points out that the reason why it evolved was so plants didn't have to be dumb and rely on water to carry their junk to fertilize other junk. Right. You know? They're like, how about wind? Or how about that bat? Yeah.
Starting point is 00:04:47 Or how about that beetle? Yeah. Or how about that bird pooping it out? That's right. Yeah. And like I said, I think pollen grains or plants spread their seed literally. Plant pollen is what amounts to plant sperm. Yeah.
Starting point is 00:05:03 Like I always go to the kids science pages to research first off. Right. I mean, they're good. They're colorful. Yeah. If we wanted pollination very simply, you know, people reproduce, animals reproduce, they need male and female parts. Plants and flowers are no different.
Starting point is 00:05:18 They need male parts to connect with the female parts to make an egg. And in this case, pollination is how it's done. Right. It's basically how that sperm, the pollen, reaches that egg. Which is the ovule. Yeah. Right. And then another magic happens.
Starting point is 00:05:33 That's right. But let's talk about the way it looks, first of all. Yeah. There's like pretty cool. There's a lot of different looks to pollen depending on the plant. Yeah. And all of these variations, it can be like a cone, literally a pine cone. Yeah.
Starting point is 00:05:49 And look at, you know, just look at microscope pollen on Google images and you'll see all sorts of weird colorful shapes and sizes. Yeah. Some look like blowfish. Yeah. Others look like Sputnik. Really? Yeah.
Starting point is 00:06:02 And you can see the Sputnik. Some have ribbed edges for, and all of these adaptations are, or mutations, I guess they became adaptations, allow that pollen to kind of better ensure that it's going to be carried to where it needs to go. Yeah. It has a purpose. It's not just like, hey, this one would look neat if it looked like a starfish. Exactly.
Starting point is 00:06:24 It serves its purpose. Mix it up. In the end. It's kind of what amounts of basically wings because they're carried on the wind. Oh yeah? Yeah, like dandelion pollen that's carried on the wind. True. Well, dandelion is self-pollinate too.
Starting point is 00:06:38 We'll get to that though. Yeah. They're slippery little guys. Yeah, they are. They're also high in phytonutrients as well. Oh yeah? Dandelion greens are. Oh, the stems?
Starting point is 00:06:48 No, the leaves. Oh, the little leaves. Yeah. The yellow part. So here's the rule of thumb. Here's a New York Times article that came out very recently about phytonutrients and how we basically bred them out of our food. And the rule of thumb is the bitterer or more bitter, the plant, the higher it is in
Starting point is 00:07:12 phytonutrients. Phytonutrients have kind of a bitter astringent taste. And we tend to not really like that. So we stopped eating those things over time and replaced them with sweet things that aren't necessarily good for us, like potatoes and other starches. Yeah, well, bitter things can also kill you. That's probably the reason why. Maybe so.
Starting point is 00:07:30 That's a pretty good point. But bitter stuff that you know won't kill you. Yeah, sure. Dandelion leaves go out and eat some right now. Yeah. But back in the day, I bet people were like, that tastes bad and it killed tuk-tuk, so let's just not eat it. Right, exactly.
Starting point is 00:07:45 Yeah. All right. So should we talk about pollination? Talked a little bit about pollen. Yeah. Should we talk about how plants make little baby plants? Right. And it's pretty simple.
Starting point is 00:07:56 Like I said, the male part, and it really helps to follow along if you go to a handy-dandy little visual aid I found, because they really break down the male parts and the female parts. The female has the pistol, and that's P-I-S-T-I-L. And within that, you have the ovary, which sits down low in the plant, and the style, which is a long, thin appendage, I guess, that contains pollen tubes. Right. And then at the top, you have your stigma, which is going to catch the pollen. Yeah, and that's the female part, right?
Starting point is 00:08:33 That's the lady. Okay. Don't be confused because it is phallic in nature. Yeah, true. But it's still the female part. And the male has the filament, which is a long stem, and then the anther at the top, which holds all the pollen. Yeah.
Starting point is 00:08:46 And that's pretty much the long and short of the parts. And is that just angiosperms that you're describing, or is that all pollinating plants? I think these are just the angiosperms. Well, we should say quite explicitly that there's basically two ways that plants can pollinate. There's gymnospherms and angiosperms. And the big difference between the two is that gymnospherms, literally that means naked seed, which by the way, gymnasium means place to be naked.
Starting point is 00:09:14 Genosium in German. Did you know that? Yeah. So, gymnospherms, naked seed, there's nothing protecting the seed once it's produced. Yeah. And a seed is just a fertilized ovum, or ovule, right? Yeah. Angiosperms produce something to protect that seed, whether it's a shell, like a nut,
Starting point is 00:09:32 or fruit, like an apple, with the seeds inside. Right. Because an apple is just an enlarged ovule, ovary. And the seeds are the fertilized ovum. Yes. And they also pollinate, cross-pollinate or self-pollinate. Right. Those are the other two differences.
Starting point is 00:09:50 So, you were saying what, of dandelions, self-pollinate? Well, they can do both, but they do have a little, a cool little feature. They basically grow up, you know, this is when there's still the little yellow flower. Mm-hmm. They have these little florets that grow up. And if you look, well, you probably can't see. If you look really, really close, though, these little florets that grow up, and as it grows, it carries the pollen on its little stem, and then eventually gets to a point
Starting point is 00:10:17 where it doesn't start growing up anymore, and it splits, and then starts curling back on itself to, you know. No way. It picks up its own pollen from its own style. And it's self-pollination. It's not gross or like perverted. There's a lot of plants out there, though, that have mechanisms to pollinate. To prevent them from self-pollinating.
Starting point is 00:10:42 Yeah, it can be good or bad. That's what I couldn't figure out. Well, the plants somewhere along the way figured out, like, hey, the wider the gene pool, the better off we are, because the more room there is for adaptation, mutations, and then adaptations, right? Yeah, but in here, the author said, ideally, it cross-pollinates, but I don't think that's the case always. It's not ideal.
Starting point is 00:11:02 It's just some doing some don't, right? I mean, if you look at it like from just an animalistic or an organism viewpoint, right? Like with us. If you just get a bunch of Mennonites together and they just reproduce with one another, there's going to be defects that just are propagated throughout this little gene pool. But if the Mennonites spread out into the larger country as a whole, those defects are going to, I guess, be kind of watered down by the size of the gene pool. I think it's the same thing with self-pollinating and cross-pollinating.
Starting point is 00:11:37 Yeah, because it's interesting, because things like peanuts are self-pollinators, and that's why they thrive, but corn has a mechanism to not allow itself to self-pollinate. Like there, I think the sperm is ready at a different time than the ovule is ready to accept it. Correct. So it's a timing thing. The thing is, peanuts would probably be able to talk if they didn't self-pollinate. And they sound like Jimmy Carter.
Starting point is 00:12:06 So there's a lot of mechanisms that plants have to prevent themselves from self-pollinating. Some might have either just male plants and just female plants. Some may be where the male part of the plant has both male and female flowers, for example. The male flower might come out before the female flower on the same plant, so that they're not the timing's off a little bit. And then there's some that are just like, they'll signal a biochemical marker if pollen from the same plant gets near the ovule, it'll just basically turn barren, so it's incapable of fertilizing itself.
Starting point is 00:12:51 Or like corn where the timing's thrown off, so they rely on cross-pollination, which is pretty cool. For food lovers, there's no place on earth like Mississippi where sweet, spicy, and smoky flavors satisfy your spirits. Wherever you wander, plan today at visitmississippi.org slash dining, Mississippi, Wanderers, welcome. The war on drugs impacts everyone, whether or not you take drugs. America's public enemy number one is drug abuse. This podcast is going to show you the truth behind the war on drugs.
Starting point is 00:13:21 They told me that I would be charged for conspiracy to distribute 2,200 pounds of marijuana. Yeah, and they can do that without any drugs on the table. Without any drugs, of course, yes, they can do that, and I'm the prime example of that. The war on drugs is the excuse our government uses to get away with absolutely insane stuff. Stuff that'll piss y'all. The property is guilty. Exactly. And it starts as guilty.
Starting point is 00:13:43 It starts as guilty. The cops. Are they just like looting? Are they just like pillaging? They just have way better names for what they call like what we would call a jackmove or being robbed. They call it civil acid. Be sure to listen to the war on drugs on the iHeart Radio App, Apple Podcast, or wherever
Starting point is 00:14:04 you get your podcasts. So let's get explicit again here. Gymnospirms. Yes. Acid seed. How does this happen? Like we'll use the example of a pine, a loblolly pine, because it's fun to say, but that's a conifer.
Starting point is 00:14:26 Conifers are ancient. I believe they were the first pollinating plant. Oh, really? Yeah, I think so. Nice. So let's talk about it. Well, the pine cones, they're little male pine cones, little female pine cones. You might not realize that.
Starting point is 00:14:39 You've got quite a show going on in your backyard at certain times of the year. And basically, once you get the two together, you get a male pine cone and a female pine cone together. The male pine cone fertilizes, well, the pollen comes in contact with an ovule and the pollen starts to go to town. It absorbs a bunch of water. Yeah. Well, the female pine comes a little sticky, too, that helps, by the way.
Starting point is 00:15:02 It does. Helps collect the pollen. Right. So the female or the pollen, the male part of the pine cone, germinates and it starts growing what's called a pollen tube, which basically allows this pollen to directly fertilize the ovule. Once that happens, the ovule basically becomes a seed and the seed is released from the pine cone.
Starting point is 00:15:25 They go everywhere. And then they're eaten by birds and pooped out elsewhere or carried along in their trampled by rhinoceros. Sure. Who knows what just got loose from the zoo. But then that seed is carried along. But it's not protected by anything. It's just a seed.
Starting point is 00:15:41 Right. And hence a naked seed, hence gymnasperms. Right. So angiosperms, they have kind of like a similar process, whereas there's a pollen tube that's grown and the male pollen has come in contact with the female pollen and all that. Yeah. And we're talking about flowers in most cases here. With angiosperms, they're the only ones that flower and produce fruit.
Starting point is 00:16:02 Yeah. So when you think about your garden with the honeybee and all, that's angiosperm. Right. And that's a non-naked seed and that's where the fruit comes in or the shell comes in. There's angiosperms have developed a mechanism to protect the seed, to better ensure survival. And if you think about it, to entice the things that transport these seeds to go ahead and do their thing. Yeah.
Starting point is 00:16:30 There's like every flower has some sort of cool shape or scent or color or something that matches with some little insect or bird or bat that's going to be enticed, like the bumblebee in the fox club. They go hand in hand because it fits up there just perfect and it has a little colorful landing strip on the bottom petal to guide the bumblebee in. Yeah. And it's just like nature's, it's just like harmonious. Right.
Starting point is 00:16:57 There's that one orchid that I believe Darwin predicted the existence of a type of humming bird that had a very long curl beak that had co-evolved with it and he was absolutely correct. So cool. Memorized in that movie adaptation. Yeah. That's a great movie. And then...
Starting point is 00:17:15 You can learn a lot from that movie. Yeah. It's a great attention. Yeah. Anything that... What's his name? Charlie Kaufman writes? Yeah.
Starting point is 00:17:23 Well researched. Agreed. The fruit is another thing too. Animals love to eat fruit. Yeah. The fruit is basically once a fruit, piece of fruit drops to the ground, that means those seeds are ready to go, they're ready to become seedlings. But first they need a fox to eat the apple, carry it in its stomach over several meters
Starting point is 00:17:41 or miles or whatever and then poop it out and then you have seeds that are basically just planted. That's amazing. They take purchase and a new tree begins. Where his seed, her insides were a rocky place where his seed could find no purchase. So pollen grains are actually created, I guess we should step back a second and talk about meiosis. That's the cells are dividing and growing, eventually you get a little pollen.
Starting point is 00:18:11 It looks like a little dust spec to our eyeball but it contains the sperm, it's not actually the sperm. Right. It contains the sperm therein. And the pollen is in pollen sacs at the end of the stamen which we talked about and that little two-lobed antler and then eventually it'll find its way to the stigma and travel down to the ovary and in the case of angiosperms there are two sperm that are used, I don't think we said in the case of gymnosperms it's only one of the sperm is used, right?
Starting point is 00:18:45 Yeah, in a pollen sac there's two sperm but you just need one for the angiosperm you need two. One is actually fertilizing the egg and the other is developing into endosperm together alongside in what will eventually be the seed and if you think that sounds gross like the gymnosperm, I'm sorry the endosperm is like a protein basically to keep it all alive. Yeah, it keeps the seedling happy and healthy. So when you're eating corn you're actually eating the endosperm, each corn kernel is actually, you know, it's like that starchy endosperm.
Starting point is 00:19:19 Right. Which the seed loves to eat itself and that's true. So we talked about bees, we talked about birds, foxes, mentioned poop a couple of times. Fox gloves. Yeah, and you were saying that like basically every flowering plant especially has some sort of mechanism to attract at least one kind of bug or animal that's been proven to help pollinate, transport this pollen. And so I mean for the most part we enjoy them like you like the scent of, you know, a good
Starting point is 00:19:55 flower, right? Oh yeah. Sure. But you might not like the devil's tongue. Yeah. Which is a Sumatran plant that apparently reeks so badly, smells like a decomposing flesh basically. Yeah.
Starting point is 00:20:11 Did you see this thing? I've seen it before. Yeah. It's really remarkable. Yeah. It's like two feet tall. It basically flowers or blooms like once every like 10 years or 20 years or something like that, right?
Starting point is 00:20:24 I'm not sure. If it's the same one I'm thinking of, then yeah. But it's stinky. Right. And the reason why it's stinky is because it pollinates with the help of a type of carrion beetle that's attracted to decomposing flesh. Yeah. So the plant attracts this beetle that likes to eat decomposing flesh by putting out the
Starting point is 00:20:41 smell of decomposing flesh. That's so gross. Yeah. It's spectacular. It is. You know? Yeah. And the philodendron is something you might have in your house.
Starting point is 00:20:51 It actually does the same thing, but it doesn't stink always. There's actually a chemical reaction that takes place and heats it up to emit this odor that the beetle is attracted to. Right. Which sounds pretty gross too. Yeah. But it all works. And I would Google that the Sumatran devil's tongue.
Starting point is 00:21:07 It's pretty cool looking. Like the flower itself is two feet. It's not like, oh, what a long stem. Right. It's just this huge flower. It's amazing. It's something like, was it Fox Glove that provided a landing strip for bumblebees? Yeah.
Starting point is 00:21:21 So flowers in general typically have certain types of, like their color will be based on the kind of creature that helps pollinate it, whether it's diurnal, meaning it's awake during the day, or nocturnal, meaning it's awake at night, right? Right. I guess that's in case of bats and stuff like that. Yeah. And then our old friend Nectar is a big lure, and basically Nectar is around, right, just because it tastes delicious and is enticing.
Starting point is 00:21:50 From what I understand. To the pollinators. Yeah. It's basically like a little enticement. Like you said, for like a bee or something or a bird. Yeah. Come get it because it's placed by the stamen. That's right.
Starting point is 00:22:03 Or the way that the anthors are situated, just the way they're placed in the flower, if it gave it an advantage to bump up against that bee, then it's going to be successful in the long run. Yeah. And live out as a species. That is nice stuff. It is pretty good. So, Chuck, we've reached a point where, I mean, ever since we started selectively breeding
Starting point is 00:22:22 plants, domesticated crops. Like, hey, that's pretty. Right. Or, hey, I like this banana. Yeah. Or that's hearty, and it grows in my awful, hot area that I live in. Exactly. Many reasons to do so.
Starting point is 00:22:37 Right. You know, we wanted to keep plants, we wanted to keep the bad stuff out, keep the good ones we wanted in. Yeah. But it never became more crucial until we started genetically modifying crops. Yeah. And now all of a sudden, not only are the corporations saying like, hey, man, you can't cross-pollinate with our stuff or else that's patent infringement.
Starting point is 00:23:00 Yeah. And nearby farmer says, I'm not using your seeds. It's the bees. You can't blame me. Right. And the farmers who don't want GMO stuff in their crops say, hey, man, you need to keep your crops over there because I don't want your GMO crud in here. I have an organic farm.
Starting point is 00:23:17 Exactly. And your junk is blowing by the wind. It's a touchy subject. We should do that as a whole. Oh, yeah. GMOs. I agree. The idea of like patenting genes in general and let alone like crops is, it's really interesting.
Starting point is 00:23:31 But there's been some pretty clever, simple ways of getting around this problem that's posed by pollination of GMO crops with non-GMO crops. Yeah. Well, distance is obviously one thing. Yeah. It's pretty simple. Don't put my farm near your farm. Yeah.
Starting point is 00:23:48 But they have to do all kinds of studies to see how the wind reacts and how, like, how far does that bee fly? Yeah. And they found in certain parts of Africa, bees will go about four miles, three kilometers. Yeah. And that's their range for food. That's, you know, that's a lot. Yeah.
Starting point is 00:24:04 But I mean, just using that kind of thinking thought process though, like, okay, well, this, you know, there's this guy's growing this over here, so I can't grow this here. Right. That will prevent that kind of pollination, though. Yeah. Another thing they can do is sort of like with the corn, they can time their crop rotation to time out. So where they're flowering at different times and not interfering with one another.
Starting point is 00:24:25 Right. And it's a touchy subject, like, from what I understand, there's a lot, a lot more going on than, you know, is preferred by, like, the organic farmers of the world. Sure. And in the GMOs, they can then say that you're infringing just because they cross pollinated to their crop. Right. Even though you didn't buy their seeds or even want their seeds, if a bee carries their
Starting point is 00:24:54 seeds, their crops pollen over to your crops and then you start to develop plants that have the GMO characteristics that's patented according to the corporations you're infringing on their patent. It's very tricky ground there, isn't it? I don't think it's tricky ground. If you ask me, you should not be allowed to have a patent on any living organism. Oh, well, yeah. You know what I mean, though.
Starting point is 00:25:16 That's my opinion. It gets tricky in courts and in studies and in corporations. The courts, though, tend to side on the corporation's side, typically. Yeah. Let's do that one, though, soon. GMOs. Yeah. All right.
Starting point is 00:25:32 So, that's it for pollen. If you're interested in how pollen causes allergies, then you should listen to our How Allergies Work episode. That was pretty good. Yeah, I was going to recommend that. Nice work. Thanks, man. So, if you want to learn more about pollen, in the meantime, you can type that word in
Starting point is 00:25:46 the search bar at HowStuffWorks.com. And since I said search bar, it's time, of course, for a message break. The war on drugs impacts everyone. Whether or not you take drugs. America's public enemy, number one, is drug abuse. This podcast is going to show you the truth behind the war on drugs. They told me that I would be charged for conspiracy to distribute 2,200 pounds tomorrow one hour.
Starting point is 00:26:12 Yeah, and they can do that without any drugs on the table. Without any drugs. Of course, yes, they can do that, and now I'm the prime example of a tax. The war on drugs is the excuse our government uses to get away with absolutely insane stuff. Stuff that'll piss you off. The property is guilty. Exactly. And it starts as guilty.
Starting point is 00:26:28 It starts as guilty. The cops. Are they just, like, looting? Are they just, like, pillaging? They just have way better names for what they call, like, what we would call a jack move or being robbed. They call civil acid for it. Be sure to listen to the war on drugs on the iHeart Radio App, Apple Podcasts, or wherever
Starting point is 00:26:50 you get your podcasts. How's that New Year's resolution coming along? You know the one you made about paying off your pesky credit card debt and finally starting to save your retirement? Well, you're not alone if you haven't made progress yet. Roughly four in five New Year's resolutions fail within the first month or two. But that doesn't have to be the case for you and your goals. Our podcast, How to Money, can help.
Starting point is 00:27:15 That's right. We're two best buds who've been at it for more than five years now, and we want to see you achieve your money goals. And it's our goal to provide the information and encouragement you need to do it. We keep the show fresh by answering list of questions, interviewing experts, and focusing on the relevant financial news that you need to know about. Our show is chock full of the personal finance knowledge that you need with guidance three times a week, and we talk about debt payoff.
Starting point is 00:27:37 If, let's say you've had a particularly spend-thrift holiday season, we also talk about building up your savings, intelligent investing, and growing your income. No matter where you are on your financial journey, How to Money has got your back. Millions of listeners have trusted us to help them achieve their financial goals. Ensure that your resolution turns into ongoing progress. Listen to How to Money on the iHeart Radio app, Apple Podcasts, or wherever you get your podcasts. And now, how about some listener mail?
Starting point is 00:28:03 Yeah. We have a correction. It's been blowing up lately. Oh man, I'm sorry. You know it's crazy, that's the second time I've done that in a podcast. On that same thing? I don't remember what the other podcast was, but I've mentioned it before and we've gotten tons of corrections about it.
Starting point is 00:28:20 And I didn't learn my lesson. Well this guy was really nice about it, so I'm going to read his. And it's an important correction, because anytime you're talking about drugs. So to recap in the PTSD podcast, we've got the two drugs, Beta Blocker, called Propaninol, which helps with PTSD, confused with Propofol, which is what killed Michael Jackson. And so this is from Chris. He's a big fan. He's listened to every episode on his commute in Southern California, which we know stinks.
Starting point is 00:28:52 So he said what we just said about getting the drugs confused. He said, I can see how you guys can mix it up, because the names are very similar, but they're significantly different, obviously. Propaninol is relatively mild and commonly prescribed and very little potential for overdose while Propofol is a very powerful drug with extremely high potential for overdose and rarely administrated outside of strictly monitored medical settings. It is actually a hypnotic agent that must be administered intravenously, as we talked about Michael Jackson's drip, and is often used in conjunction with general anesthetics
Starting point is 00:29:26 like most general anesthetics. This steep dose response curve significantly increases the risk of overdose, where the effective dose is only slightly below a lethal dose. That's kind of scary. Yeah, it really is. I mean, when you're on that, you're right along the border. Yeah. Well, he says Michael Jackson's case is extremely rare, so he was essentially exposing himself
Starting point is 00:29:47 to risks similar to those associated with general anesthetics used during surgery with a high potential for overdose and death on a daily basis for relatively trivial purposes, which were, in this case, insomnia. Yeah, but from what I understand, he had years-long insomnia. This guy was not sleeping at all. They would give him everything first, and then they'd try that last resort. Sometimes it still wouldn't work. Really?
Starting point is 00:30:18 Yeah, he was really in bad shape at the end. Well, he probably had a resistance to certain things like that. So, Chris goes on to say, I'm not certain about the exact amount of risk posed by a propofol administration, but I believe the risk of death is something on the order of tenths of a percent, meaning he would have died according to the statistical model within a couple of years of daily use, like pretty much guaranteed. Right. Frankly, he would have been better off using heroin that whole time in spite of his ironically
Starting point is 00:30:46 strict yet poorly informed anti-drug stance. So, that's from Chris. Thanks, Chris. That was a genuinely awesome email. Yeah, it was good. And I'm sorry, everybody, for getting so wrong. Well, I mean, the names are just confusing. Yeah, but I mean, one's like a blood pressure medicine, the other one's like pretty much
Starting point is 00:31:02 a general anesthetic. I know, but what gets me is that half of the emails were like, well, yeah, they just sound alike, so you goofed it, and half of them were like, those drugs couldn't be any more different. Right. Like, you really thought that, you know, it's just, it's like a verbal typo. Right. Thank you, Chuck.
Starting point is 00:31:19 Thank you for letting me off. So anyway, if you have a correction for us, we really do like to get those. We like to know what we're talking about. Sometimes we get things wrong. Sometimes I get things wrong, but we do want to be corrected in the nicest way possible, because that's usually who gets their letter read, right? Exactly. Yeah.
Starting point is 00:31:40 You can tweet to us at S-Y-S-K podcast. You can join us on facebook.com. Stuff you should know. You can send us an email to stuffpodcast at discovery.com. And you can join us at our home on the web, the greatest website in the history of humanity. And if you should know, all one word.com. With over a hundred thousand titles to choose from, Audible.com is a leading provider of downloadable digital audiobooks and spoken word entertainment, go to audiblepodcast.com
Starting point is 00:32:25 slash no stuff, K-N-O-W-S-T-U-F-F to get a free audiobook download of your choice when you sign up today. Be sure to listen to the war on drugs on the iHeart radio app, Apple podcasts, or wherever you listen to podcasts.

There aren't comments yet for this episode. Click on any sentence in the transcript to leave a comment.