Stuff You Should Know - The Duality of Caffeine

Episode Date: January 14, 2016

Caffeine is a heck of a drug - at the same time it's both good and bad for you. Learn the good, bad and ugly about this everyday stimulant in today's episode. Learn more about your ad-choices at http...s://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

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Starting point is 00:00:00 On the podcast, Hey Dude, the 90s called, David Lasher and Christine Taylor, stars of the cult classic show, Hey Dude, bring you back to the days of slip dresses and choker necklaces. We're gonna use Hey Dude as our jumping off point, but we are going to unpack and dive back into the decade of the 90s.
Starting point is 00:00:17 We lived it, and now we're calling on all of our friends to come back and relive it. Listen to Hey Dude, the 90s called on the iHeart radio app, Apple Podcasts, or wherever you get your podcasts. Hey, I'm Lance Bass, host of the new iHeart podcast, Frosted Tips with Lance Bass. Do you ever think to yourself, what advice would Lance Bass
Starting point is 00:00:37 and my favorite boy bands give me in this situation? If you do, you've come to the right place because I'm here to help. And a different hot, sexy teen crush boy bander each week to guide you through life. Tell everybody, ya everybody, about my new podcast and make sure to listen so we'll never, ever have to say. Bye, bye, bye.
Starting point is 00:00:57 Listen to Frosted Tips with Lance Bass on the iHeart radio app, Apple Podcasts, or wherever you listen to podcasts. Attention everyone on earth, get in your nearest plane and fly to one of a few cities to see us for SYSK Live, the live show. Yes, an all new live show, by the way. Yeah, oh yeah.
Starting point is 00:01:17 We are sold out in San Diego, San Francisco, in Austin, Texas. That's right. But you can still get tickets in Dallas, Atlanta, Birmingham, and New Orleans. That's right. And also, I, this is Chuck, by the way. That's Chuck.
Starting point is 00:01:31 I will be appearing on noon, January 16th in San Francisco at the Eureka Theater as part of Sketch Fest on the amazing JV Club podcast. Yes. From the amazing Janet Varney. Yes, part of the Nerdist Network. Yeah, and I think I'm gonna be revealing like all kinds of childhood and teenage truths.
Starting point is 00:01:51 That's gonna be awesome. So if you wanna know more about what I was like as a teen, January 16th at noon at the Eureka Theater is where to do it, and you can get those. Just go to the SF Sketch Fest site. Yeah. And navigate to that date, and you can get tickets there.
Starting point is 00:02:04 Right on. But otherwise, we will see you on our warmer climbs winter tour. Yeah, and go check out sysklive.com for any ticket info, and all that is brought to you by Squarespace. Welcome to Stuff You Should Know, from house.works.com. Hey, and welcome to the podcast. I'm Josh Clark.
Starting point is 00:02:29 There's Charles W. Chuck Bryant. Jerry's over there, totally throwing us off with some new Pocus Pocus 2016 head stuff. What? Yeah, yeah, she's messing with it. So we, you guys don't know this, because through the power of the magic of editing. And publishing.
Starting point is 00:02:50 And publishing. You think we've just never been gone from the office? Yeah. But we've been gone. I have no idea what episodes we released. I've been so out of it. Yeah, I took six weeks of paternity leave. Woo, and I did by proxy.
Starting point is 00:03:04 And you did by proxy. Yeah. So we've been gone from the studio for a while, and just wanted to say it's glad to be back, buddy. Yeah, it is nice to be back. And it's good to see you again. It's been a long time. What's happened in the meantime?
Starting point is 00:03:19 I lost another tooth. Yeah. My stupid front. The tooth next to the one that came out broke off at a Falcons game. Oh, well, there you go. God was cursing you for being at the Falcons game. So I have another stupid flipper
Starting point is 00:03:35 and another eight months of. Eight months early. Yeah, until I get the permanent implant. So again, I'll be out on tour with no tooth. You can't even see it. Like you have to literally like, pull your gums back or your lips back to your gums. Or if I laugh a lot,
Starting point is 00:03:52 which I'm trying to just lead a more somber life. Well, I plan on making you laugh a lot on stage. So people might see it then. What else? You got a dog. Yeah, we got a puppy named Momo. You want to talk about Momo? Momo is very sweet.
Starting point is 00:04:03 She's a sweet little shizu poodle mixture. How's that going? She's a little fluff ball. Very good. House trained or? Yes, good. Right off the bat. We crate trained her.
Starting point is 00:04:14 And at first I was like crates are mean. You should have put a dog in crate. And then I started to read up on it. They love it. Yes, it's like her den. It's her little room, like her bedroom. In fact, when we took away the crate from our youngest dog, Charlie,
Starting point is 00:04:27 because of we needed a breakfast nook, she was kind of like, dude, you took my room away. Yeah, that was my room. We plan to keep her crate around like as long as she wants it, but just she won't be penned in it against her will at certain times. Until she's house broken,
Starting point is 00:04:44 which I mean, she's basically there. It's just, we're like, what are you doing? You're about to pee, you know? Right, right. She doesn't actually have accidents in the house. We're just, you know, staying on top of it. It's great.
Starting point is 00:04:56 What else happened? We had holidays. Yes. Good Christmas in the New Year's, I guess. Yumi's birthday. Oh yeah, of course. We had a birthday, yeah. And it was just a nice time off.
Starting point is 00:05:07 Like I had this big to-do list. Yeah. And none of it got done because it was raising a puppy replace that. Yeah. How's your kid? Ruby's great, man. And I did the same thing.
Starting point is 00:05:17 I had a big to-do list and found myself just kind of being like, oh, could you do this? Or I could just like play with my kid. Right, or watch Making a Murderer. Yeah, I did watch all that. She was staying here in like a day. We'll talk about that. We probably shouldn't talk about it.
Starting point is 00:05:31 People want us to do a podcast on that. I know. Like a follow-up. Maybe. It's not as bad as the requests to do a podcast on the case that Serial covered. Like, I think Serial got that one covered. No, I'm not gonna get no.
Starting point is 00:05:47 No, of course not. I could maybe do a follow-up on Making a Murderer. I think we should revisit exonerations in the Innocence Project again because when we did that one, we had no idea what was going on. And now it's really like, it's really coming through. True.
Starting point is 00:06:03 So yes, let's do that. What else? Oh, I've been playing a lot of, I got a PS4. Oh yeah? I've been playing Fallout 4. With the dog? And their dog companion? Well, you can have a dog companion.
Starting point is 00:06:15 So of course I chose it. Okay. But it's really awful because the dog gets hurt a lot. And like struggles around withering and bleeding. Do you have to put it out of its misery ever? Well, no, you can heal the dog, but I went to message boards and everyone's like,
Starting point is 00:06:27 don't heal your dog. Like just trust me, it'll heal itself. Don't waste your medicine. Oh, okay, yeah. I'm sure you waste your medicine every time, don't you? Well, yeah, it's tough. Just hear the fake dog whimper. Yeah, and it's like, I'll be okay.
Starting point is 00:06:41 Yeah. Don't mind me. That's his name. So that was a big time off. Yes. We just covered. It was, and that's all that happened. Jerry, how about you?
Starting point is 00:06:53 That was great, Jerry. I'm glad you had a nice time as well. Jerry also had a nice break with her little baby Inez. She told us this through a series of blinks. She did. That we worked out over the years. Yep.
Starting point is 00:07:07 Nice job. All right, so sorry about the long intro, but I felt like we needed to catch everyone up even though you didn't know that you needed it. Right. And maybe have something to do with caffeine. Because we did such a good job when we recorded those ones that were released
Starting point is 00:07:20 over the break of predicting things we would be talking about at the time. True, yeah. Who could tell? Exactly. So I'm a little caffeinated right now, believe it or not. What a shock. I don't drink nearly as much coffee as I used to.
Starting point is 00:07:32 Yeah. It's because I really realized like, it really does have a detrimental effect on like my mood. Oh, really? My car. Car's a really good example of me and caffeine. You're a little ramped up in the car anyway, so that probably didn't help.
Starting point is 00:07:46 Right. Well, I'm working on that. Yeah. But part of working on that is just, you know, not drinking as much coffee. Yeah. I think a good title for this could be Mixed Messages because in studying caffeine, and we did one on coffee.
Starting point is 00:08:00 We dabbled in this a little bit, but all the research is, you know, caffeine can be really good for you and help a lot of things. And caffeine can be kind of bad for you. And it's kind of both or can be both. It sure seems like that unless we have like a completely misunderstood model of addiction
Starting point is 00:08:19 and the parasympathetic or sympathetic nervous system. Yeah. Unless we don't know those things, then yeah, coffee is both for sure. The weird thing is like everybody realizes that coffee, I'm sorry, caffeine. I think I'm probably gonna do that a lot this episode. Yeah.
Starting point is 00:08:36 Because they are virtually interchangeable. Sure. Not really. But caffeine, it has a lot of really bad effects on you and a lot of people know that just from having experienced it. You're right. It's the beneficial effects that are so surprising.
Starting point is 00:08:52 But they do seem to, like you say. Agreed. So Chuck, I drink, today I've had five cups of coffee and a diet mountain dew. And it is 1.40 in the afternoon. Right. What's up? Seven.
Starting point is 00:09:09 Seven, eight, nine, 10, 11, 12. Yes, I'm counting on my fingers. Got six and a half hours. I know, wow. You, six and a half hours, you've had five cups of coffee and a mountain dew. Right. And that's cutting back.
Starting point is 00:09:20 Yes. Oh man. Yeah, and it's cutting back because I, like this afternoon I won't keep going. Oh, so you stop. This will be my last probably. Really, for the day? Yeah.
Starting point is 00:09:32 Oh, okay. And I'm actually, I'm above average for the United States and I could have guessed that. Yeah. But the average for the United States is actually on the worst end of the spectrum as far as like caffeine consumption goes. Yeah.
Starting point is 00:09:47 The latest information I got is that the U.S. was 16th in the world in per capita consumption. Yeah, not even 10th or ninth or anywhere above 10th. No. No. 16th. Yeah.
Starting point is 00:10:01 If you want to know who leads the world, right now I think it's the Netherlands is what I found. I found Finland. Oh, really? Uh-huh. From 2013, that was the most recent I saw. Well, the most recent I saw said the Netherlands at 2.4 with Finland at 1.8.
Starting point is 00:10:17 Really, that is not what I saw. Really? Yeah. Where were the Netherlands on your list? I don't remember. I just saw that Finland was number one at like 2.4. Oh, wow. And like 9.6 kilograms of coffee beans
Starting point is 00:10:30 per person per year consumed. Well, I bet the top 10 is kind of interchangeable and fairly static though. Sure. As in the same-ish countries in different orders. Yeah, because I mean coffee consumption patterns, I guess they could change fairly rapidly, but they don't change in the blink of an eye.
Starting point is 00:10:49 Well, think about how much Starbucks changed coffee consumption in this country. Did ramp it up? Oh, yeah. Like think about how many people now swing by Starbucks at like 3 p.m. Whereas before they may not even have drank coffee. Yeah, don't you mean charbucks?
Starting point is 00:11:04 Yeah. Yeah. Like you have no skin in the game. I like Starbucks. Yeah, I don't really. Well, you know me. I don't drink caffeine that much. No, I know.
Starting point is 00:11:14 You're very mellow. Yeah, I don't know. I'm starting to think I should drink more coffee though. Why? Because of the health benefits. Oh, yeah. You know? We'll see, we'll get into all that.
Starting point is 00:11:24 But in the top 10, you have Netherlands, Finland, Sweden, Denmark, Germany. Scandinavia loves their coffee, apparently. Yes. Slovakia, Serbia, Czech Republic, Poland, Norway, then eventually the US. Cold countries. Not bad.
Starting point is 00:11:38 Although Brazil loves its coffee as well, I think. They're like number 10 or 11 or something like that. Good coffee. I didn't see they weren't even in my top 16, so. We had different lists made by two different caffeinated weirdos. So the US, the FDA and the AMA right now, I think they raised it to 400 milligrams a day from 300.
Starting point is 00:12:03 Just in the face of changing coffee consumption. Yeah, I think it's now up to 400 milligrams a day, as they said, should be like the upper limit of what you should drink and what is cool to drink for your health. Right. Not by being cool. You could drink 100 cups a day and you'd be super cool. Right.
Starting point is 00:12:20 That's why I drink coffee so much. Yeah, exactly. I want to be cool. And so what is that? 400 milligrams a day. That's about two eight ounce cups of coffee. 400 is? Yes, high octane.
Starting point is 00:12:36 Right, coffee. But yeah, it's no more than maybe three. Well, and that's caffeine though. That's not coffee. So you might also be drinking sodas or eating chocolate or eating on a cocoa nib. That's packed with caffeine. Yeah.
Starting point is 00:12:54 Yeah, it does show up in all sorts of surprising places. Including, I looked this up, decaf coffee as well, we should say. Yeah, still got some caffeine in there, right? Yeah, so like a cup of coffee, eight ounces of coffee, can have anywhere from like 75 to 200-ish milligrams of caffeine in it. OK.
Starting point is 00:13:16 Decaf coffee still might have like 20 milligrams. Wow. And I mean, it doesn't sound like much. But if you're pounding decaf coffee because you love coffee, but you're trying to cut back on caffeine, stuff can add up. Interesting. I knew there was some caffeine, but maybe that's not. Is that negligible?
Starting point is 00:13:34 20, itself, just if you drank one decaffeinated cup of coffee a day, yes. OK. I think on the overall effects of your health, it would be negligible. But both ways, because again, the coffee giveth, and the coffee take it away. Yeah, sure does.
Starting point is 00:13:48 It's a double-edged drug. Yeah, and it is a drug. And it's also in tea, which we'll get to as well. But yeah, it's a drug. It naturally occurs, like many drugs. But it is a stimulant called trimethylxanthine. Nice job. Chemical formula C8H10N4O2, not 0-2.
Starting point is 00:14:14 I think there's a 10 in there. What did I say, 1-0? Yeah. Which I mean, if you're on a CB or something, they get the point. Oh, man. And this podcast thing is close to CB chatter as you can come.
Starting point is 00:14:30 I have a quick segue here. I used to love talking on the CB, because my dad had one on his Jeep. Oh, yeah. And remember, when CB culture was huge in the 70s, my buddy John Pendell now is a trucker. You met John. Where?
Starting point is 00:14:45 At our New York shows, Tall Johnny Pendell. He's a trucker now. OK. And I've got to hang out and get in his truck. And he does not use a CB. And he said that he might get one, but it's not like the standard thing anymore. What is now?
Starting point is 00:15:00 Texting? Cell phones. And he said, if you really want to be a part of that big trucker culture, you can do the CB still. Well, you can just be a lone wolf. He's a lone wolf. Gotcha. Right now, he is.
Starting point is 00:15:11 He needs one of those jackets, like Lenny and Squiggy used to wear. Yeah, it was fascinating, though. We need to do an episode on trucking, because when I saw him, all I did was ask questions, basically. Yeah. It's fascinating. Does he have his own rig?
Starting point is 00:15:25 No, he doesn't own it. It means truck. Yeah. OK. Anyway, well, hey to Johnny. And he listens to the podcast now, so. Hey, Johnny. Because you don't need a CB if you listen to stuff you should know.
Starting point is 00:15:36 No, we are your CB. We'll keep you company. All right, so anyway, caffeine. He does drink a lot of caffeine. I think that's where I was going with that. Yeah, but that really had nothing to do with it. I brought up CBs because he said H10. Why don't we take a break?
Starting point is 00:15:52 And get our C legs back. Yeah. Our P legs. We're a little rusty. And P is in podcast. Not urine. I thought you meant urine. Oh, man.
Starting point is 00:16:01 I thought you meant. Oh, hey, I'll tell you something about this break. I learned that there's something called mixturition, syncope. And mixturition is, a lot of people think it means 2P. No. Urination is 2P. Mixturition is the urge to pee.
Starting point is 00:16:21 Syncope is a fainting spell. So there is a condition out there called mixturition syncope where people faint after they pee. Wow. There's also one called defecation syncope where people faint after they poop. They have no idea why. I think Elvis had the most severe case of that.
Starting point is 00:16:39 All right, well, don't let that happen to you during this break. And we will be back right after this. Hey, dude, the 90s called David Lasher and Christine Taylor, stars of the cult classic show, Hey Dude, bring you back to the days of slip dresses and choker necklaces. We're going to use Hey Dude as our jumping off point, but we are going to unpack and dive back
Starting point is 00:17:11 into the decade of the 90s. We lived it, and now we're calling on all of our friends to come back and relive it. It's a podcast packed with interviews, co-stars, friends, and nonstop references to the best decade ever. Do you remember going to Blockbuster? Do you remember Nintendo 64? Do you remember getting Frosted Tips?
Starting point is 00:17:30 Was that a cereal? No, it was hair. Do you remember AOL Instant Messenger and the dial-up sound like poltergeist? So leave a code on your best friend's beeper, because you'll want to be there when the nostalgia starts flowing. Each episode will rival the feeling of taking out
Starting point is 00:17:43 the cartridge from your Game Boy, blowing on it and popping it back in as we take you back to the 90s. Listen to Hey Dude, the 90s, called on the iHeart radio app, Apple Podcasts, or wherever you get your podcasts. Hey, I'm Lance Bass, host of the new iHeart podcast, Frosted Tips with Lance Bass. The hardest thing can be knowing who to turn to when questions arise or times get tough,
Starting point is 00:18:04 or you're at the end of the road. Ah, OK, I see what you're doing. Do you ever think to yourself, what advice would Lance Bass and my favorite boy bands give me in this situation? If you do, you've come to the right place, because I'm here to help. This, I promise you.
Starting point is 00:18:18 Oh, god. Seriously, I swear. And you won't have to send an SOS, because I'll be there for you. Oh, man. And so will my husband, Michael. Um, hey, that's me. Yep, we know that, Michael.
Starting point is 00:18:29 And a different hot, sexy teen crush boy bander each week to guide you through life step by step. Oh, not another one. Kids, relationships, life in general can get messy. You may be thinking, this is the story of my life. Just stop now. If so, tell everybody, yeah, everybody, about my new podcast, and make sure to listen,
Starting point is 00:18:48 so we'll never, ever have to say bye, bye, bye. Listen to Frosted Tips with Lance Bass on the iHeart radio app, Apple Podcasts, or wherever you listen to podcasts. Have we got it together? That was like a half a second. Are we good? Yeah, I guess so. All right.
Starting point is 00:19:12 We're going to give it another stab here. So caffeine, I think that's what we were talking about. It's a drug, and in its pure form, Chuck, is a bitter, bitter-tasting crystalline powder. That's right. It's actually very closely related, at least in its effects, to opioid antagonists like heroin, cocaine, caffeine. And we'll talk a little more about the effects on the brain.
Starting point is 00:19:40 But it does have these effects, and it uses the same mechanism as these drugs. And therefore, it can cause addictions, just like these drugs as well. Yeah, and like I said, it occurs naturally. It's in the coffee bean, and in chocolate, and tea. But it's also added artificially in things like soda. And I looked up the sodas to get the most recent amount.
Starting point is 00:20:07 And Pepsi one right now, I think, has the most caffeine. Man, do you remember jolt and vault? I used to drink a ton of vault. Sure you did. Well, I would drink one right before the podcast, remember? And I'd just be like talking 1,000 miles an hour? Yeah, it's a good old days. I've settled down quite a bit.
Starting point is 00:20:24 You have. I'm happier for it. Pepsi one at 57 milligrams. Tab is number two at 48. Diet Coke 46. You will work your way down to regular old Coca-Cola at 33 milligrams per 12 ounce can. And the FDA regulates how much caffeine
Starting point is 00:20:42 you can put in a soda. A soda. A soda. That's the key. That's right. If you're an energy drink, like Red Bull or any of those other gross tasting things, I don't like them personally, but people love them.
Starting point is 00:20:55 I just don't like the taste. But that's the workaround for the FDA because they're not considered sodas. They can put lots of caffeine and sugar to the tune of about 80 milligrams per 8.3 ounces. Which you're like OK. In the case of Red Bull. That's a lot of caffeine.
Starting point is 00:21:13 It does seem like a lot, but some people love to take it even further. And there's like those five hour energy shots. Oh yeah, I have had those before. Those are two. I have not tried it before. I don't know why. I think I was doing construction work
Starting point is 00:21:26 and I was really tired. And I was at the big box store and it was right there. Check out. I was like, let me try this thing. Yeah. And it ran me up. I felt like a speed head. So in that little two ounce shot,
Starting point is 00:21:39 there's 200 milligrams of caffeine. No wonder. Like a high end amount in a coffee in that little two ounce shot. OK. And I think those are the, like coffee has the most of any beverage. I think espresso ounce for ounce has the most.
Starting point is 00:21:56 Well, I mean from the coffee bean at least or espresso bean. Oh yeah. Not like an artificial drink is what I meant. Yeah. We got an espresso maker and it has some pronounced effects. It's crazy how different it is from coffee. Yeah, I like an espresso every now and then. Sure.
Starting point is 00:22:14 And I like my coffee every now and then. Yeah. But just every now and then. If you want the health benefits though and you're like, I don't drink that much coffee, you should just be injecting pure caffeine, Chuck. Can you do that? They do it to mice.
Starting point is 00:22:26 Yeah, that's a good point. As we'll see later on. True. I should probably, again, it's been several weeks since we've done this. I need to probably throw out a disclaimer there. That was a joke. Right, don't inject caffeine into your bloodstream.
Starting point is 00:22:41 If you can even get your hands on pure caffeine, do not inject it. You probably shouldn't inject anything, let alone the pure form of anything. Because even too much water can kill you. Always remember that, everybody. Even too much water can kill you. And I did look into caffeine overdoses
Starting point is 00:22:58 because I was curious. And it doesn't happen much because you'd have to drink so much of something that it makes it unlikely. But there have been overdoses blamed on caffeine pills. Like, OK, what's the milligram amount? What's the dosage amount that it got? I can't remember.
Starting point is 00:23:13 This one kid died in Connecticut, like a 19-year-old, that I think he had like a dozen or two dozen caffeine pills. Wow. And I think the deal with caffeine pills, it's concentrated and it hits y'all at once. Yeah. So taking a lot of it is just like overdosing on any kind of stimulant, I think.
Starting point is 00:23:32 Yeah, it's a stimulant. Yeah. That's some weird stuff to you. Including killing you. And like you said, Chuggers, we already talked about coffee in the coffee episode, right? Yes. But some of it bears repeating.
Starting point is 00:23:44 Like, the lighter the roast, the higher the caffeine content typically. Because the roasting process actually bakes out a lot of the caffeine. I thought you were going to make up a clever rhyme. Like, the lighter the roast, the darker the toast or something. No, that doesn't make any sense. The rhyme's got to at least make sense.
Starting point is 00:24:03 Or else it's just rhyming words. How about, the lighter the roast, more caffeine than most? What about that? That's great. That actually makes sense. And so if you want to extract the most caffeine out of your diet, I actually came across a website called Bulletproof Exec.
Starting point is 00:24:23 You know that bulletproof coffee thing? Or you put butter in your coffee? No. It's like a diet thing. I think it aids in pooping and. Butter in your coffee? Yeah, butter in your coffee. It's called Bulletproof.
Starting point is 00:24:34 It's actually not bad. If you like that, though, take it one step further and use coconut oil. Oh, OK. That's even better. Because it's got a little, it's like an Almond Joy creamer. Oh, wow. But like an oily version of it.
Starting point is 00:24:47 Anyway, this Bulletproof Exec, they had a post about maximizing your caffeine intake. So you can suck it to your underlings throughout the day or whatever, most efficiently, right? And one of the things that they said is that grapefruit, you should eat more grapefruit because grapefruit contains something called Narragin or Narragin. And it actually slows the removal of caffeine
Starting point is 00:25:13 from your brain. So you enjoy its effects longer. Nice. Yeah. So a morning breakfast in the 1950s of coffee and half a grapefruit is all you needed. Yeah. And then your noon cocaine bump just to keep you going.
Starting point is 00:25:28 Just for drinking Coca-Cola. Yeah, exactly. And if you also, if you want to maximize your caffeine intake from coffee, you should look at the beans you're drinking. So Arabica, which is, I think, the most prevalent coffee, has its 1.5% caffeine. But Robusta, 2.4%. That is Robusta.
Starting point is 00:25:47 As far as I know, that's the highest caffeine content naturally of any coffee bean. So a light roast Robusta is going to basically. With your grapefruit. Yeah. It'll be like getting kicked in the chest by a mule. Wow. And does it not sound appealing?
Starting point is 00:26:03 That's what every Bulletproof Exec wants. Wow, shows you how to be a more efficient Robert Barron. So let's get down to this, man. How does caffeine actually affect your brain? Because it does affect your brain. The whole point behind taking coffee and stuff like that is, as the guy who wrote this article, oh, the three guys who wrote this article, including you.
Starting point is 00:26:25 Yeah, I did a little update on this. I forgot. Using caffeine, it's a form of self-medication. Of course. That's why most people drink it, I think, to get that boost in the morning. Sure. Or in the middle of the afternoon.
Starting point is 00:26:38 Yeah, and I'm sure people love the taste and stuff. It's not like they're holding their nose and forcing the strength down their throat. Well, that's what five hour energy is for. It doesn't taste very good. Do they not? I've never tasted one. I've always wondered.
Starting point is 00:26:50 But I've never wanted to experience this effect so badly that I tasted it. Yeah, I mean, it's like just that synthetic fruit taste. Does it taste like medicinal at all? Yeah, it's just not good. Huh. In my opinion. Well, it's just two ounces.
Starting point is 00:27:07 You get it over with real quick, right? Yeah, you just sock it down and you're done. Punch a wall. So how does it work on the brain? It tricks your brain, actually, by mimicking something called adenosine. And it's kind of remarkable, actually, because what it does is it mimics adenosine
Starting point is 00:27:28 and then does the opposite of what adenosine does, which is to try and help you sleep. It's pretty cool. Yeah. So you have a sleep-wake cycle, right? Part of the sleep cycle is adenosine latching on to the adenosine receptors on your neurons. And they're weepy.
Starting point is 00:27:44 Yeah, it does make you sleepy, because it slows the function of your neurons down. It's a big buzz kill, basically. It's a drag adenosine is. Well, it's great. It is, yeah, it helps make you sleepy. And what caffeine does is it gets in there to the same receptor.
Starting point is 00:28:02 It binds to the same receptor as adenosine, because your brain thinks it's adenosine. Yeah, it puts on its adenosine costume, basically. Pretty much, which consists of a sparkly one-piece jumpsuit. It's a onesie. And it not only doesn't slow your neurons down, it apparently speeds them up. Yes.
Starting point is 00:28:23 So your brain starts going, hey, wire, that's part one of what caffeine does to your brain. It not only doesn't slow your brain down, it prevents the thing that does slow your brain down from slowing your brain down, and it actually speeds your brain up. Yeah. And not only that, but adenosine usually,
Starting point is 00:28:42 or not usually, adenosine always causes your blood vessels to dilate, and caffeine causes them to constrict, which sounds bad, but one of the pluses, and we'll get into the benefits, but one of them is constricting, it can maybe help you avoid headaches and migraines, and that's why caffeine is in things like anisin, or my old reliable BC or goodies headache powders
Starting point is 00:29:08 that I use contain caffeine. Yeah. That's my secret hangover helper. BC powder. BC or goodies, it just acts fast. Bloody Marys, they work really well too. Both together. A little, yeah, I got to.
Starting point is 00:29:21 No. Yeah, so caffeine is a vasoconstrictor, right? That's right. It constricts your blood vessels, and like you said, that can actually help your headaches, because a lot of headaches, vascular headaches, I guess is what they're called, are when your blood vessels are too big,
Starting point is 00:29:37 and the change in pressure in your brain gives you this horrible headache. Right, so while this is happening, your body thinks these neurons are firing, your pituitary gland says you must be in trouble, because you're supposed to be going to sleep, buddy. Yeah, there's clearly a bear coming at you, and I don't know about something's wrong.
Starting point is 00:29:55 So let's send you some adrenaline. We've talked ad nauseam about fight or flight, and your body thinks that's what's going on when you drink caffeine, so it says here, you need this adrenaline, because like you said, you got a bear coming your way, and all the hallmarks of fight or flight kick in. Which, man, this used to be like our...
Starting point is 00:30:16 Go to. Yeah, and now it's just such an accepted part of everything. That's right. Do we even need to say the things anymore? Yeah, go ahead. Okay, so your pupils dilate, your breathing becomes more rapid, you get more breaths. If you're eating something, you stop digesting it,
Starting point is 00:30:34 because your stomach doesn't matter at that point. That's right. Superfluous, your blood pressure rises, your liver releases sugar in the bloodstream, so you can get some extra energy. You're ready to go, basically. It's like time for some action. Yeah, and that's why you drink that cup of coffee,
Starting point is 00:30:51 you might feel tense, like you in the car. Yes. Or agitated. Right. It's because your body thinks you're about to be in a big fight with the car next to you. Yeah. Which ends up, it's this weird reverse cycle.
Starting point is 00:31:05 It ends up causing that fight. Yeah. You know what I'm saying? You'll also find if you drink a lot of coffee, like me, the big knot develops in between your shoulder blades, just below your neck. Nice. It's just yet another result of your muscles tightening
Starting point is 00:31:20 and you being ready for action, thanks to the fight or flight syndrome. So your brain has been kept from getting drowsy. Yeah. It's been sent into basically like a Lucy-esque assembly line of chocolates. Yeah. The fight or flight syndrome is kicked in.
Starting point is 00:31:37 That describes like a significant amount of the effects of coffee, but there's a big one that's missing still, that we haven't touched on. And that is, it's pleasurable effects. It makes you feel good. Yeah, because it's a stimulant and it's a drug. And just like all the other illicit illegal drugs,
Starting point is 00:31:53 this one is just accepted, but it has the same effect. It's going to release dopamine and that's the pleasure center activation center. Right. And it makes you want more of it. And so that dopamine's flowing and your body's like, man, this is great.
Starting point is 00:32:07 Yeah. So it doesn't actually, it's like heroin and cocaine. It doesn't actually make you overproduce dopamine, but it keeps dopamine from being absorbed as quickly. So you get its effects longer and more than you would if you weren't under the influence of the drug. Just like heroin, just like cocaine, caffeine,
Starting point is 00:32:25 again, it uses the exact same mechanism. It's just to a weaker degree, which is why like, again, people aren't shooting caffeine. Right. And this is a bad idea. This, we should point out varies from person to person, the effects of caffeine on the body because it metabolizes differently in everyone.
Starting point is 00:32:44 So some people might be like, I don't get jittery at all or I can go right to sleep after coffee, other people. I'd like to see those people in an espresso shot of Robusta. Yeah. Yeah, I'll bet they wouldn't be singing the same song. Other folks, I used to wait tables
Starting point is 00:32:59 and I would have people come in at like lunch and say like, no, no, no, I can't, like their friend would get a cup of coffee after. They'd be like, no, no, no, I'll be up all night. Yeah. I'd be like, are you serious? Yeah. What?
Starting point is 00:33:12 Did you say that too? No, I would just always, yeah, I always think it was a little weird, but like I said, it may keep them up all night. Yeah. That's their own jam. People know their bodies. So don't, don't just go with the decaf in that case.
Starting point is 00:33:25 So we, there are plenty of negative effects like keeping you up all night, as well as positive effects with caffeine. And we're going to talk about those right after this. On the podcast, hey dude, the 90s called David Lasher and Christine Taylor, stars of the cult classic show, Hey Dude, bring you back to the days of slip dresses
Starting point is 00:33:56 and choker necklaces. We're going to use Hey Dude as our jumping off point, but we are going to unpack and dive back into the decade of the 90s. We lived it. And now we're calling on all of our friends to come back and relive it. It's a podcast packed with interviews,
Starting point is 00:34:11 co-stars, friends, and non-stop references to the best decade ever. Do you remember going to Blockbuster? Do you remember Nintendo 64? Do you remember getting Frosted Tips? Was that a cereal? No, it was hair. Do you remember AOL Instant Messenger
Starting point is 00:34:25 and the dial-up sound like poltergeist? So leave a code on your best friend's beeper, because you'll want to be there when the nostalgia starts flowing. Each episode will rival the feeling of taking out the cartridge from your Game Boy, blowing on it and popping it back in as we take you back to the 90s.
Starting point is 00:34:40 Listen to Hey Dude, the 90s called on the iHeart Radio app, Apple Podcasts, or wherever you get your podcasts. Hey, I'm Lance Bass, host of the new iHeart podcast, Frosted Tips with Lance Bass. The hardest thing can be knowing who to turn to when questions arise or times get tough, or you're at the end of the road.
Starting point is 00:34:58 Ah, okay, I see what you're doing. Do you ever think to yourself, what advice would Lance Bass and my favorite boy bands give me in this situation? If you do, you've come to the right place because I'm here to help. This, I promise you. Oh, God.
Starting point is 00:35:10 Seriously, I swear. And you won't have to send an SOS because I'll be there for you. Oh, man. And so will my husband, Michael. Um, hey, that's me. Yep, we know that, Michael. And a different hot, sexy teen crush boy bander
Starting point is 00:35:23 each week to guide you through life, step by step. Oh, not another one. Kids, relationships, life in general can get messy. You may be thinking, this is the story of my life. Just stop now. If so, tell everybody, yeah, everybody, about my new podcast and make sure to listen so we'll never, ever have to say bye, bye, bye.
Starting point is 00:35:43 Listen to Frosted Tips with Lance Bass on the iHeart radio app, Apple Podcasts, or wherever you listen to podcasts. All right, so you've got the one, two, three punch. Your body is enjoying the caffeine. It's blocking that adenosine. You're gonna feel alert and awake. Right.
Starting point is 00:36:10 It's got that adrenaline going and it's rewarding you with the dopamine. So it's gonna make you wanna drink coffee, but I mentioned the vicious cycle. It is a bit because after coffee comes the inevitable crash, like any stimulant drug and you want more of it to get back up again.
Starting point is 00:36:28 So you're gonna have that fatigue and maybe even slightly depressed feeling and then you have a little bit more of that caffeine and it's gonna get you going again and that's sort of the cycle that you find yourself in which will eventually, even though you might not think it is, it's gonna affect your sleep patterns.
Starting point is 00:36:45 Yeah, that cycle kind of continues on into the next day, right? Yeah. So coffee has a half life of six hours. Caffeine. Caffeine, yes, I told you, I predicted this. That's all right. Caffeine is a half life of six hours
Starting point is 00:36:59 where if you drink a cup of coffee that has 200 milligrams of caffeine at noon, at 6 p.m. you will still have 100 milligrams of caffeine in your system. That's right. It's like at six you drank a red bowl and a quarter right then, right? Not exactly what you want.
Starting point is 00:37:21 And then at midnight you would have 50 milligrams left which is like more than a Coke. It's like a Mountain Dews worth of caffeine in you. Again, not really what you want. So as the authors of this article, including you point out, you may fall asleep but that caffeine stimulation is probably gonna keep you from getting deep sleep.
Starting point is 00:37:42 And deep sleep is what you really genuinely need. And I think after researching this, reading that sentence, I went, because I think like I basically like that, that is how I live my life is I don't sleep deeply. Even though I sleep deeply, I don't think I get actual deep sleep. You know what I mean?
Starting point is 00:38:02 Right, so then you wake up craving the caffeine again. Exactly, and that's where that cycle goes on and on where you just, it's really tough to quit it. It's very interesting. If you are pregnant, there are some studies that suggest, and we should say there have been a lot of caffeine studies. Yeah, this article says like 19,000 since the 60s. I'm sure there's 20,000 by now.
Starting point is 00:38:29 Easily. And they are somewhat conflicting. So we always are gonna say like this study suggests because they aren't hard and fast rules. But if you're pregnant, some studies suggest that 300 milligrams or more per day could lead to low birth weight in your little baby. Kids, I read one article, like five experts
Starting point is 00:38:50 talk about caffeine in children, and they all said, that's not great for kids. No, kids drink coffee these days, do they? Yes, but in the form of like those like coffee drinks that are super sweet and creamy and everything. But they drink, like if you walk around them all, you'll see like eight year olds with like a coffee drink just walking around like it's nothing.
Starting point is 00:39:09 I went to the mall the other day for the first time in probably five years. Yeah, how was it? It was awful. Was it? And I hated every minute of it, and I'm not going back. The mall's another place that, it's another thing that puts that like knot in my back.
Starting point is 00:39:20 Just too many people in one place. Yeah, it's no good. And with the baby strollers, it's just like I wanted to put a spoon in my ear. Which mall? I went to Perimeter. Okay. I mean, there was a, we got new pillows,
Starting point is 00:39:35 so I was like, I had to go to the mall to get pillows. You know? Yeah. Because you got to put your head on it, even through the plastic case. Oh yeah, no, I know. I've been pillow shopping. You know what I mean?
Starting point is 00:39:47 Your pillows are great though. Oh yeah, if you get a good one. Yeah. I've been on a bad run lately with pillows where I've gotten, well that's two. I got one, wasn't very happy with it, got a second one to replace it. Not, it's better, but I'm still not quite happy with it.
Starting point is 00:40:02 Do you just use one pillow? Uh huh. Really? I use one pillow. Wow. Yeah. Anything else I'm like, oh my neck. I got to have one under my head.
Starting point is 00:40:11 I got to have one behind my head, between my head and the headboard. And then one tied to your face. No, and then a clutch, you know, to hold on to. Okay. Like to wrap up with. Wow. It's the best.
Starting point is 00:40:22 Yeah? Yeah. That's three pillows. Yeah. You sleep with three pillows. Well, Emily, and yeah, six total. Jerry, tell us in blinks how many pillows you sleep with. Three?
Starting point is 00:40:35 Three as well. I think you're under pillowed. I guess so. I sleep with one third the pillows you do. Here's a pillow tip though. If you're buying, just wait for a Macy's one day sale. Oh yeah. Because pillows are expensive, good ones.
Starting point is 00:40:48 Yes they are. And 50% off. But worth it. Because a lot, yeah, very much. Get your hands on a good pillow. Yeah, and Macy's does it twice a year, I think. Maybe Memorial Day and Labor Day are their pillow sale days.
Starting point is 00:40:59 Well, they had one going on after New Year's. I am wrong. There you have it. All right, so we were talking about sleep and the shopping mall, where kids were drinking coffee. It all comes together. It does. But all five of the experts said your kids shouldn't really
Starting point is 00:41:14 be having too much or any caffeine. And they didn't say because of the health effects, basically it was just like sugar. You don't want your kids, you know, heart rate increased a lot and their blood pressure increased. And it's just not going to do yourself any favors as a parent to have a caffeinated child. But I genuinely believe that you can go through experiences
Starting point is 00:41:42 like that as a younger kid. And it'll make you a keyed up adult, a higher strung adult. Oh, you think? I do. I have come to believe that. That experiences in childhood very prominently shape who you are as an adult. Very much so, I've come to believe that.
Starting point is 00:41:58 Yeah, I guess if you're 13 and drink a lot of coffee and you get anxious, you probably be an anxious adult. I believe that. Probably keep drinking coffee. Probably to stave off the anxiety. When did you start drinking coffee? Or did you always drink a lot of soda, too? No, I guess it was more of a grown up for both.
Starting point is 00:42:20 Oh, really? Yeah, I drink a lot of Kool-Aid as a kid. And the straight up tons of sugar in the Kool-Aid. And I drank some, we called it pop, like Fego and Pepsi and stuff up in Toledo. But I mean, I think it was like as an older person, 20s, 30s, that I started drinking coffee in earnest and coke. That's how it should be, I think.
Starting point is 00:42:47 Sure. I definitely didn't drink coffee as a kid. No. That was gross. Yeah. I did, too. The taste of it was just really foul, I thought. But I really learned to love the taste of coffee.
Starting point is 00:42:59 And I enjoy a nice hot cup of coffee on a camping trip or a cold day. I just never took up the regular habit. And not for any reason other than I just, I don't know, just never grabbed me that night. Never took it up? Yeah. It wasn't like a stand, though.
Starting point is 00:43:15 I'm not going to start drinking caffeine. Yeah. And everybody who drinks coffee can rot. No. Because my brother-in-law and my mother-in-law drink more coffee than any human's alive. More than me? They're both wonderful.
Starting point is 00:43:27 Yeah, they're like, let's brew a pot of coffee, not a cup of coffee. Yeah. And let's just drink it until it's gone, then brew another pot, you know? Yeah, I know. But they get a lot done. They're very accomplished people.
Starting point is 00:43:41 They sleep several inches above the bed. One of them's a general in the Marine Corps that shows you where he is. Yeah. Or actually, that's my mother-in-law. All right, how about some health benefits? All right. There are a lot, believe it or not.
Starting point is 00:43:56 They've done a lot of studies, and they found everything from helping out to not develop Parkinson's disease to dropping your risk of various cancers, cirrhosis. How about this? Two cups a day supposedly will cause an 80% drop in the odds of developing cirrhosis. That's amazing.
Starting point is 00:44:19 Yeah. I drink a little bit. So maybe I should drink coffee. I wonder if that has to do with stimulating the fight or flight syndrome, where your liver releases more sugar to give you more energy or something like that. Maybe. But what's weird then is so that would be more sugar
Starting point is 00:44:39 in the bloodstream, right? Yeah. Too much sugar in the bloodstream can lead to diabetes, right? Right. Well, coffee actually is shown to reduce your risk of diabetes. Yeah.
Starting point is 00:44:49 There's this Harvard study that involved 126,000 people over 18 years. They followed their coffee intake. That is a good study. It's a great study, unless they fudged the results. But saying they didn't, what they found was that people who drink one to three cups of coffee a day are 9% less likely to contract diabetes, right?
Starting point is 00:45:09 Yeah. You think it ends there? No. It does not. So people who drink six or more cups of coffee per day, if you were a man, your chances of contracting diabetes were reduced by 54%. That's substantial.
Starting point is 00:45:22 And for women who drank six or more cups a day, their chances of contracting diabetes were 30% of developing diabetes, 30% reduction. I got another one. Four cups a day, 50% less chance of mouth and throat cancer. And I don't know if it was this Harvard study or another one said it could reduce suicide risk in adults even. Kind of makes sense, I guess, in one way.
Starting point is 00:45:50 But which way? I don't know. I was thinking, I don't know. I take that back. Well, maybe you run from self-harm even. Maybe. Like you flee or fight. Or if it just, maybe it could battle your depressive systems
Starting point is 00:46:03 by picking you up or something. I don't know. Yeah, that's a much better explanation of mine. Mine was stupid. There's evidence that it prevents cavities, actually. Oh, really? Yeah, which is kind of surprising because that is if you just, if you're doing a study on coffee,
Starting point is 00:46:21 that's if you don't put anything in your coffee. Yeah. Put cream and sugar in. Yeah, you're going to get your cavities on, right? You kind of do both, right? Just depending on your mood. I typically go toward black. Right, but every now and then you
Starting point is 00:46:33 throw a little vanilla creamer in there. Every once in a while, yeah. Yeah, if I want to treat. Oh, yeah, special treat. Right. But caffeine can hurt your teeth in that it causes teeth clenching, too. Well, which is one reason I'm losing teeth
Starting point is 00:46:49 is I grind my teeth at night. Yeah. So maybe I shouldn't drink more coffee. It could be, yeah. But like you said, at Givethin, it takes away. Do I want teeth or do I want my liver to hang in there? And no diabetes. Right, yeah.
Starting point is 00:47:02 Good point. Alzheimer's, the Bird Alzheimer's Institute in Tampa did some experimenting on lab mice, injecting them with caffeine, like you said earlier. And not only did it protect them against developing Alzheimer's, but it helped reduce symptoms. If they already had it, they haven't tried it on humans yet. But as it goes with mice, many times it goes with humans.
Starting point is 00:47:23 Yeah, hopefully. Yeah. We could all be injecting caffeine at some point. That, to me, is also counterintuitive, too, because Alzheimer's disease is potentially a buildup of plaques in your brain that's the result of not getting enough deep sleep. Because when you sleep, your glial channels expand,
Starting point is 00:47:41 and your brain is bathed, then cerebrospinal fluid cleans out those plaques. But it only happens when you're sleeping very deeply. But if you're not getting very deep sleep with coffee or caffeine, then I would think there'd be a higher risk of Alzheimer's. It's befuddling. It is. And I've also found conflicting studies on memory.
Starting point is 00:48:02 Johns Hopkins says that it's a memory enhancer, but I've seen other studies that say it's memory de-hancer. Yeah, so again, it's like it's tough to get down to the brass tacks when you have conflicting studies. If you exercise, coffee is your best friend, caffeine is. Yeah, I've heard of Olympic athletes that will shoot espresso right before a race. Yeah, well, not only does it give you
Starting point is 00:48:31 a jolt of energy and everything, but apparently it has ergogenic properties, which means that it delays fatigue. And it helps your muscles use glycogen in their energy stores more efficiently, too. So it can help you run better. Interesting. As far as cognitive abilities, the one study I found from Johns Hopkins Medical School
Starting point is 00:48:56 said that while you think it is increasing your cognitive abilities, what it's really doing is just taking you back to normal for a short period. That is chilling. Yeah, and then when it wears off, you're actually below. Man. Yeah, I don't know. I hate to think that.
Starting point is 00:49:12 I don't want to quit coffee, though. That sucks. Quit smoking. Yeah. You lost weight. Yeah. Keep your coffee. That's another thing, though, I did during this break,
Starting point is 00:49:23 is put some of that back on. We'll drink coffee and go exercise. All right. If you want to know more about caffeine, you can type that word into the search bar. How stuff works, and don't forget, in this case, the E goes before the I. Since I said search bar, it's time for Listener Mail.
Starting point is 00:49:44 This is from Maddie in Virginia. Hey, guys, I'm a 22-year-old college student in Virginia. I want to start out by saying thank you for the wonderful podcast. Oh, I'd like to see you else again. You see this one? Let me explain, guys, how you've helped me. I'm a sufferer of extreme anxiety and depression.
Starting point is 00:50:01 I've had these issues to a varying degree since middle school. However, events occurred in my life throughout the past few years that have made them much worse. Got to the point last semester where I was not able to go to class, do homework, or play on my sports team. Thankfully, my family, friends, and my school, with their help, I was able to work everything out in a much better place.
Starting point is 00:50:22 Very curious person and loved learning and acquiring knowledge. This is where you guys come in. Though I had trouble going to class, I still had that thirst to learn. So whenever I was in a bad place mentally, I would throw in my earbuds, play stuff you should know, podcast, and zone out. During these bad days, at times, when
Starting point is 00:50:38 I would listen to you guys, there were some of the only instances where I would smile or laugh. I really want to thank you for putting in all the hard work, making a great show. I know that you guys help people not only gain valuable knowledge, but you also improve lives and put smiles on many faces. I don't think you'll read this on the air. Psych.
Starting point is 00:50:56 And I don't even know if you all will even receive this email. Yeah. Double psych. But if you do, and it's right on the podcast, I just want everyone listening to know if you're going through a tough time and are struggling, things will get better.
Starting point is 00:51:07 There are always people who care about you and who will help you. Nice. That warms our cockles. Yep. My friend. And hang in there. What a wonderful message.
Starting point is 00:51:17 It does sound like trite things to say, you know, like. Yeah, unless you're going through some. Time heals wounds. And it's darkest before the dawn. But they're trite and true for a reason. Because they aren't, what? Trite and true, I think you just. Trite and true.
Starting point is 00:51:30 Yeah, but I think you just improved the phrase, did I? Yeah, but they're not trite. They're true things. Hang in there, people. That's one message. If you want to get in touch with us, you can send us an email to stuffpodcast.howstuffworks.com. You can tweet to us at S-Y-S-K podcast.
Starting point is 00:51:50 You can join us on facebook.com. And as always, join us at our home on the web, the luxurious stuffyoushouldknow.com. For more on this and thousands of other topics, visit howstuffworks.com. On the podcast, Hey Dude, the 90s called David Lasher and Christine Taylor, stars of the cult classic show, Hey Dude, bring you back to the days of slip dresses
Starting point is 00:52:23 and choker necklaces. We're going to use Hey Dude as our jumping off point, but we are going to unpack and dive back into the decade of the 90s. We lived it, and now we're calling on all of our friends to come back and relive it. Listen to Hey Dude, the 90s called on the iHeart radio app, Apple Podcasts, or wherever you get your podcasts.
Starting point is 00:52:44 Hey, I'm Lance Bass, host of the new iHeart podcast, Frosted Tips with Lance Bass. Do you ever think to yourself, what advice would Lance Bass and my favorite boy bands give me in this situation? If you do, you've come to the right place, because I'm here to help. And a different hot, sexy teen crush boy bander each week to guide you through life.
Starting point is 00:53:02 Tell everybody, ya everybody, about my new podcast and make sure to listen so we'll never, ever have to say. Bye, bye, bye. Listen to Frosted Tips with Lance Bass on the iHeart radio app, Apple Podcasts, or wherever you listen to podcasts.

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