The Dr. Hyman Show - Environmental Toxins: The Health Crisis You Can't Ignore | Dr. Joseph Pizzorno

Episode Date: July 17, 2024

Everyday exposure to toxins are silently wreaking havoc on our well-being, causing a surge in chronic diseases and health complications. In this episode, I'm joined by Dr. Joseph Pizzorno to dive deep into the hidden dangers of environmental toxins. Learn about practical detoxification pathways, foods that support detox, and effective methods like sweating to eliminate fat-soluble toxins. Plus, discover how reducing your exposure to heavy metals and synthetic chemicals can dramatically improve your health. In this episode, we discuss: The startling link between lead exposure and cardiovascular disease Persistent organic pollutants found in everyday items The impact of heavy metals on prostate cancer, heart disease, and diabetes How increased fiber intake helps eliminate toxins by preventing reabsorption in the gut How regular sauna use can help eliminate toxins that are difficult to remove through other means View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by Rupa Health, Pendulum, Armra, and Purity Coffee. Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com. Pendulum is offering listeners 20% off their first month’s subscription of Akkermansia for gut health. Visit PendulumLife.com and use code HYMAN. Save 15% on your first order of ARMRA Colostrum and unlock the power of 400+ functional nutrients. Just visit TryARMRA.com/Mark or use code MARK. Visit PurityCoffee.com and use the code DOCTORSFARMACY at checkout to get 30% off your first order.

Coming up on this episode of The Doctor's Pharmacy. Our third area now that's a huge problem after the toxins is they damage our DNA. So when you look at the research on the correlation between a bile of a particular toxin and a particular disease we're looking at, if you do it according to age, you don't see very many correlations

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Pendulum is the only company in the U.S. that manufactures and sells live acromantia mesenophilia. If you want to try it for yourself, Pendulum is offering my listeners 20% off their first month of acromantia subscription with the code HYMAN. Just head over to PendulumLife.com to check it out. That's P-E-N-D-U-L-U-M-Life.com with the code Hyman for 20% off. Now, before we jump into today's episode, I'd like to note that while I wish I could help everyone by my personal practice, there's simply not enough time for me to do this at scale. And that's why I've been busy building several passion projects to help you better understand, well, you. If you're looking for data about your biology, check out Function Health for real-time

lab insights. And if you're in need of deepening your knowledge around your health journey, well, check out my membership community, Dr. Hyman Plus. And if you're looking for curated, trusted supplements and health products for your health journey, visit my website, drhyman.com, for my website store and a summary of my favorite and thoroughly tested products. Welcome to The Doctor's Pharmacy. I'm Dr. Mark Hyman. That's pharmacy with an F, a place for conversations that matter. And if you've wondered how environmental toxins play a role in our health and what you can do about them, I know you're going to love this podcast because it's with one of the experts on this topic, Dr. Joe Pizzorno. He's a mentor of mine. He's a transformational leader in medicine. He has been instrumental in the development of functional medicine and has worked over half a

century in this field, establishing the protocols and advancing the academic, scientific, and clinical path for natural, functional, integrative medicine and environmental medicine. He was the founding president of Bastia University, which is a naturopathic college in 1978. And he coined the term science-based natural medicine. He's just a legend. His textbook of natural medicine with over 100,000 copies in four languages across five editions is a game changer. I use that a lot to learn what I know.

He's co-authored or authored six textbooks for doctors and has also written a textbook called Clinical Environmental Medicine. He's the editor-in-chief of the PubMed indexed IMCJ, which is the most widely read peer-reviewed journal in the field. He's a founding member of the board of directors of the Institute for Functional Medicine, where he served as chair. And he's a licensed naturopathic physician, educator, researcher, and spokesperson, and the co-author of many books. So Dr. Joe Pizzorno and I have worked together for years and he's always been interested in the role of environmental toxins in our health. Since 1960 or so, when

Rachel Carson wrote her book, Silent Spring, we began to understand the role of these toxic chemicals in our health. But Dr. Pizzorno goes way deep on this and helps us understand the ubiquitous nature of these compounds, how they affect our health, both petrochemical compounds, heavy metal compounds, what they do to our bodies and how to start to think about addressing these and improving our body's ability to detoxify them and reducing our exposure. So if you're living in the 21st century and you're exposed to environmental toxins, which means all of us, definitely you need to listen to this podcast with Joe Pisorno.. So let's dive in. Welcome Joe to the Dr. Sormer podcast. You know, Joe, we've known each other for the better part of three decades. We've worked together at the

Institute of Functional Medicine on the board for decades now on the founding board. And you know, you've been someone I've learned so much from and relied on to actually learn functional medicine wow and uh your textbook of natural medicine was my go-to guide for learning about this as i kind of evolved in becoming a functional medicine doctor and i also you know um your encyclopedia for natural medicine was sort of a consumer version of that textbook that helps so many people navigate the world of natural medicine. For those who don't know Joe, you've heard the introduction, but he's an icon in the field of natural medicine, integrative and functional medicine. He's basically, I would say, infused the DNA of what functional medicine

is with naturopathic principles, which is sort of an early version, I would say, of what functional medicine was. And he started at uh he you know he's been just such a inspiration for me and i think without him i don't think this field would be where it is today and many of you haven't heard of him because he's not out there as much in the public eye but he's done so much hard work so much deep research so much deep science about about the things that are really plaguing us and you know what really is been impressive for me for the last few years in your work has been the focus on environmental toxins. Thanks.

And it's something that we talk about a lot in the space we're in. It's certainly not something we learned about at all in medical school, other than acute poisoning. And it wasn't really considered part of our toolkit to look at toxin exposure, the role of toxins in our health, the way of diagnosing toxic load, the way of treating toxicity, the whole idea of detoxification was considered quackery, but it's actually central to everything we do.

And I think this is not a new topic. I mean, Rachel Carson, 60 years ago, i mean rachel carson 60 years ago more i think more than six years ago wrote her book silent spring and she sounded a warning that we used to these man-made chemicals we now call them forever chemicals are destroying the biosphere are destroying ourselves and you know in 2024 we really haven't listened to her uh we have actually poisoned ourselves in ways that i don't think she even could imagine. And I think we see exponential growth of chemicals. I think the European Chemicals Agency said there's more than 144,000 manmade chemicals

in existence. The Department of Health in the US estimates that 2,000 new chemicals are being released every year and they're not really tested. Department of Health in the US estimates that 2,000 new chemicals are being released every year and they're not really tested. The WHO estimates that 12 million people die every year from diseases caused by air, water, soil pollution, chemical exposures, climate change and ultraviolet radiation, all of which result from human activity. It's just staggering to me when you think about that because the global burden of disease studies said that there were 11 million people dying from bad food. So 12 million people are dying from toxins. That's

maybe the biggest killer, right? And it's something that we don't really talk about. So how did you come to understand that toxins were so central to human health and disease? And how did you sort of understand that we need to look at the toxic load of every single patient we see with a chronic illness? So let me actually quote one of our teachers, Dr. Sid Baker. Yeah. He is a medical doctor who I consider one of the most brilliant physicians in medicine. And he said at one of our IFM conferences, and by the way, a lot of the intellectual foundation of functional medicine came from Dr. Sid Baker. We owe him a lot. He said something when I had a lecture that I thought was just perfect. He said, you know, all medicine is

really quite simple. Get into each person what they uniquely need and get out of each person what they uniquely do not need. And get rid of the bad stuff, put in the good stuff. Exactly. So I've been in medicine now for over half a century. I've been doing this for a long time. And so as I look back and see, well, what really helped people? And for the majority of my practice up until about 15 years ago, I mainly did nutritional medicine. And I helped a lot of people. Yeah.

But as I started doing environmental medicine, I was realizing I was helping way more people. Because the body has tremendous ability to heal, we just give it a chance. But what we've done is we've poisoned our bodies with metals and chemicals so that the body can't function properly. Even if there's an amount of nutrients there, so being blocked by poisons in the environment, it's not going to get better. We now suffer the highest burden of chronic disease in every age group ever in human history. Why? Every age group? That's what's staggering. In the past, conventional medicine would say, well, yeah, people are

getting sicker because they're getting older. That's true. But they're getting older and getting sicker. We're seeing cancers now in such young age groups that we never saw before. Never. Never before. So, and then about 15 years ago, one of the wealthiest men in Canada sent his personal Learjet down to Seattle to pick me up and fly me to Calgary, Alberta.

And he said, I want to improve the health of my oil field workers. And I said, well, I'm happy to do that. But you know, while I'm a true believer in natural medicine, I'm also very objective and very scientific oriented. So I want to measure people's byload of toxins, measuring nutritional status, and measure physiological function, see what's going on, how much can I spend? He looked at me and said, blank check. If you can convince me this test is going to help improve my employees, I will pay for it. So 15 years ago, I did the equivalent of that time,

$1,500 of lab tests on 4,500 oil field workers. Wow, that's a lot of testing. So I tested nutrition, and I'll tell you nutrition, the 4,500 people, 400, and actually 4,450 of them had at least one nutritional deficiency. Yeah.

Only 50 of them did not have at least one. But right there, we have something to do. 90 plus percent. 99 percent. So then I looked at, how about environmental toxins?

I said, wait a minute, I was seeing a lot of toxins. So as they started interviewing with people, well, they were happy to get the nutrients. When we got the toxins out of the bodies, all of a sudden, dramatic improvements. Matter of fact, some are so dramatic, I actually wrote a case history on one of them that's getting so significant. So then I started looking into the research. I started realizing, studying things like, that most people don't realize, including doctors, one out of three people in North America have arsenic levels in their body

high enough to cause disease. Dr. Yeah. Dr. One out of three. Dr. Yeah. Dr. How's that correlate to? One out of four cancers is due to arsenic. One out of five cardiac deaths is due to arsenic. Diabetes, about 15%.

Strokes, about 15%. So just one toxin that's so prevalent, causing all these disease. What if instead of spending all this money on medical intervention after diseases started what we simply started decreasing people's body load of arsenic i think what happened if all those heart attacks and all that cancer didn't happen because they weren't full of arsenic yeah so i started looking at toxin after toxin lead do people realize that today one out of three dental heart checks is due to lead yeah that was shocking you know years ago I read it was in American Journal of Cardiology I think was this paper that

looked at lead levels and correlated them with cardiovascular disease and endpoints and it was it was shocking because the normal reference range for that it used to be like 40 then it was 20 and then now it's 10. and and levels over two were correlated with a higher risk for stroke heart attacks and death than cholesterol abnormalities yes and 39 of the population have levels over 2, which is just shocking. And it's not something you check when you go to your cardiologist. Yeah. I wrote an editorial, and I'm a journal, an integrated medicine and a clinician journal.

It's in PubMed. I wrote an editorial that we should be changing the standard screening. Instead of screening for cholesterol, why don't we screen for lead and arsenic? Because we'll have way better impact on people's health dealing with those than dealing with cholesterol. So let's kind of back up a little bit and talk about the toxins that are the most problem we should be concerned about. But I want to talk about like what do toxins do in the body that cause disease and how does it cross the spectrum from everything from mood disorders to autoimmune disease,

to dementia, to cardiovascular disease, to obesity, to autism? I mean, the list goes on and on. So at every level of illness from the birth to death, toxins seem to play a role. And it's not the cause of everybody who has diabetes or Alzheimer's or autism, but you know, in functional medicine, we think about the root causes and how one cause can create many diseases and one disease can have many causes. So just cause you know the name of the disease, you don't know what's wrong with you, right? You have to know what the cause is. But in the case of toxins, how did toxins actually interact with our biology to cause such problems?

Yeah, that's actually a really good question. I kind of break it into three categories. Category one is, while we pay attention to individual toxins and know a lot about the disease caused by individual toxins, number one priority is total byload of toxins. How much arsenic do you have? How much lead do you have? How much bisphenols do you have? How much salicyl arsenic you have, how much lead you have, how much bisphenols you have, how much salase you have, et cetera. Because what happens is all the toxins

cause oxidative stress and deplete glutathione from the body. Glutathione is the most important antioxidant in your body, but more importantly, it's a key way we protect our mitochondria. And the longest living people with the least disease

at the highest levels of glutathione. Yeah, that's right. If you put glutathione, your mitochondria die and you die sooner and have more disease. Yeah. Okay. So, you got decreased total load. Then we look at, okay, so now what do the toxins do individually? So, they can range from, this is where classically the main problem with toxins is, they displace nutrients from the body. So, for example, any enzyme that depends upon calcium in the body, they have high levels of lead, it displaces the calcium from the enzyme so they don't work properly.

So, they basically poison enzymes. Why is that important? Bodies are enzyme machines. What body enzymes are machines? Enzymes aren't working, our machines aren't working, and we get sick. That's number one. Direct poisoning of the enzymes by the toxic. Let's just emphasize that for a minute. Enzymes are such a huge part of our biology that one-third of our DNA codes for enzymes.

One-third of our entire genome is coding for enzymes that catalyze metabolic reactions of the body, and all those have to be functioning for us to be healthy. It's like the metabolic machinery that has to run everything. And toxins bind to those enzymes in a way that blocks their function, leading to faulty biology which leads to disease. Yes, exactly. Very well said, Mark. Exactly, that's what happens. And going on with what you said about DNA, in the second area, or third area now, that's

a huge problem after the toxins is they damage our DNA. So when you look at the research on the correlation between the biloy of a particular toxin and a particular disease we're looking at, if you do it according to age, you don't see very many correlations until about the age of 50. Because up until about the age of 50, our body is pretty able to adapt to the damage from the toxin and work around it. But when we hit about age 50, there's two big things that happen.

Number one is our body load of persistent toxins has now become much, much higher. So these are toxins that take so long to get out of our body, we can't get rid of them. So PCBs, for example. If you go to a restaurant and eat farmed fish, some of the PCBs in farmed fish have a half-life ranging from 10 to 20 years. It takes four half-lives to get rid of the toxin. So you go eat that farmed fish,

and some of those toxins will bring your body for the rest of your life. So what happens... Unless I live to 200, thenives to get rid of a toxin. So you go eat that farmed fish, and some of those toxins will be in your body for the rest of your life. So what happens… Unless I live to 200, then I'll get rid of them. There you go, right. Yeah, you have to live past 100 to get rid of them. So then, what's happening is the body load is going up. But now that the body load is going up, we've cumulically damaged our DNA, so our ability to respond to them and adapt

to them has now become limited, and now all of a sudden all the disease correlations start showing up. So total load, damage to enzymes, and damage to DNA. But there's more effects, right? There's all the immunotoxicity, which is leading to all the inflammatory and autoimmune diseases, right? The mitochondrial injury, which leads to poisoning of our energy metabolism. So there's damage to our gut lining that happens because of toxins that damage our enzymes in our gut, make our gut not be able to work. Every level of our biology, there are endocrine disruptors. They disrupt our hormonal function.

So every level of our biology, these compounds are interfering with them. And, you know, I think you know the story but the reason i got into functional medicine was i was living in china and long story short i got poisoned with mercury from the pollution there cleaning on my air filter plus i'd eaten tuna fish for decades when i was a kid and i had lots of fillings and i had a level on a challenge test of 187 which is for those you don't know like if i see someone over 20 i get worried i rarely see anybody over 100 i don't remember the last time i was 100. i've had a couple people who had higher levels than me one was a dementia patient and but you know i i

literally had every system in my body break down my gut broke down my cognitive brain broke down my immune system broke down i felt allergies system broke down, I felt allergies, everything broke down. And I developed chronic tooth syndrome and no one could fix me. I went to the doctor for years until actually I went to the conference where I first met you in Hawaii, an IFM conference in 1997, I think. And I was on a plane with a guy who was a naturopath and I was telling him, I just learned about functional medicine. I was going to my first conference and I learned about this natural medicine. Well gee, maybe you should check your

heavy metals. I'm like what really? So I did a hair analysis. I had high levels and then I did a challenge test and that was the beginning of my exploration of functional medicine. So I learned it the hard way. I learned the hard way and I find this as well in my patients. So many patients are coming in with these diagnoses and underlying it is this toxic load everyday exposure to chemicals pollutants allergens and processed ingredients can disrupt your body's natural barriers in the skin lungs and gut leading to the root cause of modern health problems like inflammation but a powerful food backed by extensive research can help strengthen these barriers. Arm Rock Colostrum.

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coffee.com with the code DOCTORSPHARMarmacy. Let's talk about the kind of big categories of toxins. You mentioned a lot of them. I just want to say this. Yeah, yeah. Immune system. Okay. So the immune system is very, very successful to imbibe all toxins.

So I just gave a lecture on PFAS, the perfluorinated compounds. And so I looked at- The forever chemicals. Yeah, the forever chemicals. Where were they from? Where did you get them from? Worst place, fast food.

Fast food? Popcorn, fast food are the worst by far. Microwave popcorn. Microwave popcorn. Okay. Because if you said regular popcorn, I don't know how to see it. Regular popcorn is fine. Microwave popcorn is problematic. Okay. When I was looking at this, I was looking at COVID and PFASs. And I looked at people who had either no COVID or mild case, compared to people who had a severe version of COVID.

The ones who got severe version had 50 to 100% higher levels of PFASs in their body compared to those who did not get bad COVID. Wow. So just a simple thing like that. Enough damage to the immune system, couldn't get rid of the COVID virus fast enough, now you've got problems. Yeah. Immunotoxicity is a real deal.

I had a patient who would bring me up with Crohn's disease and got everything and turned out she had really, really high blood levels. She detoxed her from lead and she got better. I've seen this over and over in my career. You know, some of the chemicals other than metals, which we can test for, for blood tests, and we do that at Fletcher & Howe where people can get their own blood test, but also we do it through, you know, traditional sort of uh challenge testing which is where you take a chelator and it binds the metals and you can see what's going on and and it's the test that's

really not done in traditional medicine it's a test that i do anybody who's got a chronic illness because i have to rule it out and often i'm surprised i had a guy for example who had long cobin you just mentioned uh and uh I was kind of shocked. His mercury was like 93 on his challenges, really high. His blood level was 18 and he was struggling with long COVID and gut issues. And I'm like, well, this is what's going on, right? And so I think if you start looking, you start seeing it. And I think there's a whole swath of other compounds that are, I would call them in a petrochemical sphere, that are synthesized compounds that are problematic. So what are the top compounds

that are concerning to you that we're exposed to on a regular basis and where are they found and how do we avoid them? Yeah, again, another excellent question. So when I look at the toxins, the easy way to think about them is metals versus chemicals. So we're looking at metals, arsenic, lead, mercury, cadmium, the four big ones, substantial portion of the population, have elevated levels that cause a lot of disease. When we look at the chemicals, we have perfluoronates, the PFAS, the forever chemicals. We've got the bisphenols.

So people think, oh, BPA is bad, and we get plastic that's BPA-free. Well, guess what? They put other bisphenols in that are just as bad. Phthalates, a lot of the health and beauty aids have phthalates in them. Dr. So like sunblock or makeup. Dr. Yeah, sunblock, makeup, things like this. A lot of phthalates. Well, why is that problematic? Phthalates bind to insulin receptor sites and give people diabetes. Okay. So, there are so many chemicals. I've been kind of systematically working my way through, but so far, in terms of

chemicals, these are the three I'm paying the most attention to. Dr. BPA. Dr. BPA and phthalates. Because there's just so much research. I'm not saying there aren't other problematic chemicals, but these three by themselves cost so much. There's only 144,000 other chemicals. Well, there's 12,000 of these forever chemicals.

Just one category is 12,000 chemicals. I think that's the thing that sometimes it's daunting for people because we're living in the sea of these chemicals. The newborn study that the Environmental Working group did show there were 287 chemicals in the umbilical cord of a brand new baby before it even took its first breath and 217 of those chemicals were neurotoxins everything from flame retardants pesticides dioxin pcbs uh you know dbt things that were banned have been banned before long before decades before these kids were born they're in their mothers, and they're in the environment, and they're

in these babies. So when you're born, pre-polluted. Now we're getting to the next set of toxins, and that is the herbicides and the pesticides. Agrochemicals. Yeah, industrial chemicals for agriculture. So let's look at just one category, organophosphate pesticides. If you measure the body load of pregnant women, measure the level of organophosphate pesticides, and you look at the IQ of children born to women with the top level organophosphate pesticides compared to women with the lowest level organophosphate pesticides,

and you iron out statistically all the differences in weight and ethnicity, things of this nature, just look at organic phosphate pesticide levels, highest levels, top 10% of women, seven point drop in the IQ of the children, and they never get it back. So in utero, the body is being saturated with neurotoxins. So is it any surprise the brain does not develop properly when exposed to neurotoxins, so it isn't any surprise the brain does not develop properly when exposed to neurotoxins. Dr. Yeah. Dr. So I said before that I'm focused on PFAS,

bistrinols, and phthalates. You've got to focus on the pesticides, particularly organophosphate pesticides are probably the worst of all of them, whether you've got chlorinated pesticides are problematic in many other categories. Dr. Yeah, it's true. I mean, I think I read a study that was based on farm workers, children, migrant farm workers, children, and they estimated that in the offspring of that cohort, there were 41 million lost IQ points in most children. And, you know, I think they're everywhere, right? We're sort of living in a sea of them. We can't really completely avoid them.

I'm on the board of the Environmental Working Group, and there's wonderful guides there on how to find products that are low or don't have these compounds. Skin Beef is their skincare database. They have what household products that you can buy for cleaning that are not going to pollute your environment. There's ways you can choose food based on lower pesticide counts and 30 dozen McLean 15. And there's guides to what animal protein and fish

you should eat and how to reduce your exposures. So there's a lot of ways to reduce your exposures. But, you know, part of the problem is we really can't avoid them entirely. We're all like polluted. And and I guess they were born polluted. So from your perspective as a practitioner, you can see this and you can see the data and it's kind of terrifying.

If toxins are causing all the diseases, what the heck can we do about it? Because other than trying to reduce your exposures and stop eating fish and don't eat paint chips and filter your water and have an air filter in your house and don't use these skincare products and stuff,'re still not going to be completely able to avoid them so so how do we actually start to think about this from a practical point of view of treating people with environmental toxicity and how do we

diagnose them properly so there's actually some really good news here because there are some very simple things we can do that have huge impact on our toxicity. The first thing we want to do is detox the garden. So I recommend that everybody get, have their doctor measure a laboratory test called GGTP. So GGTP is a liver enzyme that in the past was measured to determine the percentage of hepatitis. Because a person has inflammation in the liver, they start leaking liver enzymes into their blood, and you measure the enzyme in the blood and say, ah, hepatitis.

They stopped using GDT for hepatitis because other tests were found to be more reliable because GDT was reacting to other things. So it turns out within the quote normal range, 10 to 50, depending on the lab, GTT goes up in proportion to toxic load. And as you detoxify, GTT goes down. So I mentioned that Corporate Wellness Program I did. So I measured my GTT then, and it was 27. And I thought that was okay,

because I saw the research saying once it's 30, you have an eightfold increased risk of diabetes. Well, it's not concerning to go from 29 no risk to 30 more risk. I thought, well, 27 is too high. So I started getting more and more careful. So I get more careful, went down a couple of years later, down to 24. Then I measured a few years ago, it went down to 17. I just measured it two months ago, I was down to 16. So between a GTT between 15 and 20 means you've done a good job of getting rid of enough toxins that the body doesn't have to increase GTT. Why does the body increase GTT?

Because it recycles glutathione because glutathione protects us from toxins. Okay, you're down to 15 to 20, you've probably done a good job getting rid of the toxins. Now if you're below 15, it may not mean you have low toxic load, it may mean you have an inability to increase glutathione to protect you from environmental toxins. The people I've seen with the biggest problems

with environmental toxins have low GTTs. I call them the yellow canaries, they can't protect themselves. So right there, you have to monitor. Now what's the next easiest thing to do? I just want to say about that test, that test is a really inexpensive, common test. It's not part typically of your annual physical, it's not part of your typical hepatic liver function test. You have to ask for it specifically it's called gvt and i think it's something that i've been measuring on every single patient for because i can be high with alcohol like liver disease it can be high with fatty labor from diabetes

from a lot of other things but it's a it's a very important biomarker and as part of function help which is the company i co-founded it's part of the standard panel you get for, you know, under 500 bucks, 100 good by market. But it's really important because of that. Right. Yeah, right on. Very, very useful test. So that way you can monitor what's going on. So as my teacher, Dr.

Bastier would say, don't kid yourself. You know, you can think you're living healthfully, but you might have this little thing you do here and all this this food you really love you can't buy organic let me eat that anyway you can find how many your little exceptions how bad are they at enough okay the second thing to do is report the body's own natural detox system systems we spent millions of years evolving these things and we sabotage them how do do we sabotage them? A lot of the toxins are excreted from the liver into the gut, what we then expect to go out through the stools. But

we evolved that system when we're consuming 150, 100 to 150 grams of fiber a day. Now we consume 15 to 20 grams of fiber a day. Yeah. Eighty to ninety percent lower, which means that instead of going out through the stools, it just reabsorbs through intra-hepatic recirculation. So number one, eat more fiber. Eat more fiber and you'll get rid of things more effectively. Number two, only organicically grown foods. And number three, from your kitchen, remove all the plastics, remove all the nonstick things, only use glass and ceramics. It's the only safe things I'm aware of. Yeah. Filter your water. Yes. Okay. So what

we do is we have a carbon block filter right in the main coming to our house. So all the water, whether they're drinking it, whether they're taking a shower, is clean. And on our air conditioning and heating system in the house, we use what's called a Lennox filter. And it's rated at MERV 16. That's M-A-R-V-16. And that will get rid of 99.9% of the toxins in the air in your house. Yeah. Very effective. Yeah. Very important to just kind of keep your home environment clean. Keep your home environment, that's respond what you're talking about.

Filled with no toxic materials. But I think one of the things I want to bring up is this whole idea of detoxification. And it was really from a perspective of a traditional doctor and training I had, it was quackery. Our bodies detox, whatever, but there's no reason to think about improving detoxification. And yet, when we deeply look at the science of the biology of detoxification, which includes your breath, your skin, your hair, your stool, your liver, your kidneys. It's a whole system. And it requires the right building blocks to actually function. It requires the right materials and the pathways have to work. And it's a really well worked out model. And yet, we learn nothing about how to fix it, except when you're in the ER and I was an ER doctor for many

years someone comes in with a Tylenol overdose we give them this drug called drug called Nucramist which smells horrible it's not like rotten eggs you make them drink it which is like punishment for taking the Tylenol overdose and uh and then you give them a bunch of charcoal. And essentially what this compound does is boost glutathione. It's N-acetylcysteine, which is essentially a supplement, right? And I was, like, shocked when I learned that later. But it literally will rescue the liver from failure after a big insult like a Tylenol overdose, which works quite depleting glutathione. So, you know we we kind

of use it in traditional medicine we just don't realize what we're doing but i think i think what let me talk about is sort of break down how do we optimize each of the types of detoxification systems we have because it's really about building in to your life the automatic ways to upregulate the biology of detoxification in your system. And I do that every single day now because I've just built it into my life because I know I'm not a great detoxifier. I've checked my glutathione snips and I have methylation snips. I have genetics that makes me more likely to accumulate toxins. So I have to upregulate those pathways. What's your approach to sort of giving people guidance all the way from diet

to lifestyle to supplements that actually help their biology do the things it's supposed to do? Yeah, very well said. So number one and number two and number three are avoidance, avoidance, avoidance. Don't let this stuff into your body and everyday choices we make so for example do you pump your own gasoline the answer probably yes you smell the gasoline we smell that gasoline that's benzene going into your body you're smelling something that doesn't smell right get away from it so we need an N95 filter yeah right N95 filter on your nose so anyway anyway avoidance, avoidance, avoidance.

I hold my breath, it's great. I hold my breath for the entire time the gas thing is filling here. Yes it's challenging to do. So I think I'll say some specific things to do but it's every time you have a choice look at what the less toxic environment environment less the lower environmental toxin load choices that you can make so stand up when when you're pumping the gas like uh when you're having to go out to eat in a restaurant well talk to people at the restaurant and just one of your favorite restaurants i'm getting a little far field here um cook as much your own food as you can okay i just read a study on the way over here where it showed that for every meal a person eats out they didn't differentiate between fast food and and regular

restaurants fast foods are worse every time a person eats a meal out versus cooking food at home, they increase their blood levels of the phrasal chemicals by 1%. 1% per meal. Okay, so choosing where you eat your food is a way to start. Make it sure that food is organically grown. If you are going to go out, if you have a favorite place to go out, meet with the owner, meet with the owner, meet with the cooks and say, can you cook, prepare your food in ways that are less toxic?

If you are going to buy food that is from a grocery that's been prepared, coming to you in plastic or coming to you in lined paper containers, immediately put it into glass. So you might say, well, it's been sitting there since it was made and sitting there in the grocery store. So my lecture today I showed it's time dependent. Even though it's been going up as long as it's been in the grocery store, if you're leaving that container, it's still going to keep going up. So at least you can stop it there.

So put everything into glass containers. I said before, increase your consumption of fiber. But it's also simple things like you take a multivitamin in mineral. The majority of the population is deficient in multiple nutrients. I mean, US population, 99% of people are deficient in one or more nutrients. Yeah. Half are deficient in five or more. So just right there, what are those nutrients needed for? Detox systems. So use a good multivitamin mineral does not have to be

super high dosages but it has to be a little bit of everything mark i could keep talking about this again i want to just kind of cut in there because i think you know um as you're talking i i'm seeing literally like all the biological pathways in my head and which nutrient does which thing for example like you're mentioning a multivitamin, but you break that down, you're like, well, what does zinc do? Well, zinc actually increases an enzyme inside the cell called metallothionine. It's designed to get rid of heavy metals from the cell.

Or you take selenium, which you can get from food too, but that upregulates glutathione peroxidase, which is an enzyme that helps recycle and make more glutathione. We need, for example, B vitamins, folate, B12, B6, because it's important, and we'll call it methylation, which is a critical pathway that is involved in detoxification, but also actually is needed for recycling glutathione. So I think about all the basic building blocks of things that we need, and so I'm always

thinking with food. Like, what are the top foods that I can eat up-rated these pathways? So always food first. So one of the biggest categories is the whole broccoli family or cruciferous vegetables. So first off, before we get to there, because I may have a different opinion than you on something. Oh, okay. Great.

Let me go back to case history. So right where we just talked about. So I have a patient, by the way, I don't see patients. Okay. But I have family and friends by the way, I don't see patients, okay? But I have family and friends who come to me for help. So it's really good because I continue to apply my body of knowledge. You did see patients for years, didn't you? Oh, I've seen plenty of patients.

In corporate wellness, I've seen tens of thousands of patients in corporate wellness. Here's a guy who came to see me. Now listen to this. Personal history of prostate disease and heart disease and diabetes. Now, I don't know if you've heard me talk about arsenic. One third of prostate cancer is due to arsenic. About 15% of heart disease is due to arsenic. About 50% of diabetes is due to arsenic. So he comes to see me and

says, I want you to improve my health. Okay, well, here's my measures. So first thing I did, I measured his heavy metals, arsenic. His arsenic was 83. Remember I told you 10 micrograms per liter, the threshold? Was this in the blood or in the urine challenge test? No, not a challenge test. His baseline... Coming from where? Aha, good question. Okay, now going further, I did a blood test on him.

His homocysteine was 19, and he had macrocytic anemia. What does that mean? Yeah, macrocytic anemia means he can't produce enough blood cells. Now, the basis is two kinds of anemia. Microcytic anemia, which is due to deficiency of iron. You see that in women a lot, menstruating women a lot. And macrocytic anemia, which is due to deficiency of typically folic acid or B12.

Now when a person has high homocysteine levels, what are they deficient in? Homocysteine and B12. I mean B12 or folic acid. Hold on a and B12. B12 or folic acid. B12, folic acid, or B6. B2 sometimes, but yeah. Mainly folic acid and B12. How does the body get rid of arsenic?

Through methylation. How do we know if a person's having trouble with methylation? They have high homocysteine levels. Here we have high exposure to arsenic. The blood test that you can get that most doctors don't check that you should get. But again, it's on the folks in panel. Yeah.

Why did his primary care doctor not notice his homocysteine and his macrocystic anemia, his primary care MD? Anyway, here we have high arsenic exposure and inability to detoxify it because it can produce methyl groups. And guess what? Prostate cancer, heart disease, and diabetes right there. So what was the cause of his high arsenic? I just diagnosed this last week.

But now we have to find where's the arsenic coming from. So it turns out I'm from Washington State. There are a lot of high arsenic areas that are in Washington state particularly what are called the San Juan Islands, a group of islands off the west coast of Washington state. He lives on one of those islands. Is it in the water naturally? Is it coming in water naturally? So I bet you his well has high arctic levels and nobody's tested it. And that's why you need to filter your well the water it's in the groundwater, but it can come from any chicken

because they put it on the feed to prevent mold on the feed for chickens. It can come from wine that's grown in certain wineries where they use pressure treated lumber. If you have a deck, pressure treated lumber. So it's out there in our environment. And I think people don't realize how prevalent it is. How prevalent it is.

Again, one out of three people in the United States and in Canada have arsenic levels high enough to induce disease. Yes. This is not rare. So then what would you do with this person? Like talk about treatment. So how do you begin to start treating? Remember, arsenic half-life is only two to four days.

Now his, because of his methylation problem, is probably four to six days, maybe eight days. But doesn't it get stored in the tissues though? No, not particularly. Not arsenic. But lead does. Lead does, really bad. Arsenic's not good.

And mercury does. Lead, mercury, cadmium, huge storage in tissues, arsenic's not so much. Think about it, as we evolved as a species, we often encountered arsenic. So those of us who survived, we're going to get rid of arsenic. So we're really going to get rid of arsenic. So we're going to get rid of arsenic.

We didn't get too much lead in Mercury. This was a volcanic eruption. We didn't get much mercury or lead. Unless you were Andrew Jackson and you were taking calano, which is a remedy for everything in the 1800s. Or George Washington. You were doing duels and getting lead shot. I remember they tested Andrew Jackson's hair. They found the $20 bill and they found it was full of mercury and full of lead, which is why he was so crazy. Yes, that's a huge problem. So what I'm going to do for him, we're testing his water. I'll bet you his water supply is full of arsenic.

And that led to all of his disease. One thing. Well, actually, not one thing. The one exposure plus the susceptibility because of the nutrient deficiencies. Let's get back to the counter treatment approach and what we treat people with in terms of food. How do you upregulate the major

detoxification pathways using food? Yes, so as you mentioned, cabbage family foods are a great way to increase phase two detoxification in the liver. But notice folks, this is genetically determined. So some people like me, I don't upregulate my detox when I consume cabbage family food. Oh, I'm sorry.

So cabbage family foods are actually toxic for me. So why do we have all these- Wait, are they poisonous? If you can- So why do we have all these detox enzymes? Because there's constituents in food that the plants produce to protect them from predation from insects. So we developed enzymes when we come in contact with that food, those of us who were able

to upregulate our enzymes, okay, can now eat that food safely. But people like me, they talk about cabbage family foods being great for you. For me, I can't detoxify those cabbage compounds. So cabbage foods may not be good for me, but for the vast majority of the population, they're good for us.

But yeah, so, and I think the data's really interesting. I remember seeing a study in China where they looked at urine metabolites of the Brassica family vegetables, like broccoli, collards, cabbage, and all that. And they found that those were the highest levels of the metabolites, meaning people who were eating a lot of these vegetables had very low rates of cancer compared to the general world population. It's hugely beneficial. So what happens is, which we think about the hormones we produce, estrogen for women, testosterone for men. So you think about what they do in our bodies, and they're great.

I like being a man. I'm sure women like being women. But you think about what the hormone is doing. Well, once it's done its job, then what happens to it? The body's got detoxified. And it can do it through two pathways, many pathways, but it's two major pathways. And particularly estrogen, one pathway promotes cancer. One pathway prevents cancer. Now, how do you determine which pathway it goes? Eat cabbage family foods, prevents cancer. If you smoke and eat charbroiled foods,

it outbreaks the enzymes that produce cancer, cancer versions of estrogen. So our choices in the foods and what we do to the foods has a huge impact on what we upregulate. So one reason why women who eat cabbage-fabric foods have less breast cancer, because you're upregulating the right enzymes. Yeah, it's so prevalent, Joe. I just remember I once worked with a lab because I've done, you know, tens of thousands of heavy metal challenge tests. And I went with a lab that I did the test with.

I said, you know, could you actually calculate all these patients that I've sent you labs and what percent had elevated levels and give me the ranges and the distribution of the abnormalities? And I gathered the data, and it was shocking to me. And, of course, people who come to see us at the Ultra Wellness Center, where we specialize in functional medicine, tend to be sicker. So it's a sick, we call it selection bias in medicine. But 40% had very significantly elevated levels of heavy metals. And this was from a wide spectrum of diseases. It's not like just one condition. So it's out there. So, you know, we use foods like the Brassica family. We can use garlic

and onions to help boost glutathione. We can use a lot of the polyphenol compounds that are rosemary and curcumin and other compounds. So we can really just increase our polyphenol content. We need to make sure we have the right nutrients, right? So like I personally know that for me, I'm not great at glutathione production. So I take N-acetylcysteine every day. I take glycolic acid every day.

I make sure I take my multivitamin, because selenium and zinc, make sure I actually are, I'm really boosting those pathways up because I know I struggled and it has kept me feeling good by doing that over many years. And I find with my patients, I do the same thing.

And so it's really a very systematic process of mobilizing your toxin, reducing the exposures, making sure you're increasing circulation. So I make sure they're exercising, do saunas and sweating, that is a great way to reduce toxins. I think also I recommend a basic multivitamin and the right things to boost glutathione and the right cofactors for all the pathways, methylation support. It's amazing how what people do. Dr. So I'd like to add a little bit to that.

Our bodies have tremendous ability to heal. We just give them a chance. And a lot of people say, well, I want to go down detoxifying. I think the stupidest thing for a person to do is to start detoxifying before their body is ready. Yeah. Okay. So I wrote a book called The Toxin Solution. Yeah, everybody should get that book.

It's a really good book. Oh, thank you, Mark. Okay. So for the first two weeks, I teach people how to avoid toxins. Now, I'll tell you now, if you carefully avoid non-persistent toxins, within two weeks, they'll be gone. Osteic will be gone. Phthalates will be gone. Fistulas will be gone. And you immediately feel better within two weeks. Okay. Then I say now that you're stopping to expose yourself to toxins, let's open up what you call the, what the nictropaths call the munturies, the organs of elimination. Let's get your gut working properly and detoxified.

Let's get your liver functioning better so detoxifies. Let's get your kidneys functioning better so they can detoxify. Now, once your organs and the nation are working properly, two weeks each, enough time to do it, now let's start doing the saunas. Now, let's start releasing the toxins, because now your body can get rid of it. But don't release toxins until your body can get rid of them, you make yourself sicker. I think that's really an important point, Joe. I think it's really the order in which you do things. And I think you're right. I didn't know about this concept in naturopathic medicine, but that's basically

what I do. I basically fix everything else and detoxification is the last thing I do with people. Make sure all their enzymes are working. Make sure all their metabolic pathways are working. Make sure their guts work and make sure they're actually optimized in terms of their amino acid levels and their mineral levels so they can handle the detoxification process because all those things can be challenged when you do detoxification. So it's such an important concept and I think you can actually make people a lot sicker if you do it in the wrong order. And I think it's challenging and you have to kind of go slow with some people too.

We talked a little about saunas. I want to kind of back up on that because saunas kind of are hot these days and reasoning for longevity and biohacking and so forth. Can you talk about the data on saunas and particularly around detoxification and the release of environmental chemicals and how to use them for that? So I'll going to get home late Saturday night. And on Sunday, I'm taking the sauna. Okay. So if you're really interested in looking at the research on saunas, I recommend you look at the work of Stephen Genuis.

So Stephen's an MD in Edmonton, Alberta. He's done a lot of incredibly good research. Guys, if you ever get a chance to listen to him lecture, do that. It's fascinating. I had a chance to meet with him personally all about 10 years ago. We went to a vegan organic restaurant in Edmonton Alberta we sat down to eat and next time I looked up was two hours later it's so much fun to talk with so what Steven does is he takes people puts them in a sauna takes their sweat looks at what's in the sweat but said what's in the

blood measure what's in the urine, looks at what's in the blood, measures what's in the urine, and compares them. He finds toxins in the sweat that are not in the blood or in the urine. These things are so bad and the body has so much trouble getting rid of them, it just sequesters them to try to keep them out of circulation as much as possible. There's storage of the... Limit the damage. Most of these toxic chemicals are... Stuffed in the fat, stuffed in the bone, et cetera. Yeah.

So when sweating, it's a different pathway for detoxification and it turns out the body is able to get rid of a lot of toxins through sweating and have trouble getting rid of it in other ways. I've often think to myself, we evolved on the equator where it was hot and we sweated a lot. And I think we had this detoxification mechanism through the sweat that now when we move to Northern Plains, we will go for six months out of the year without sweating and we basically

undermine one of our detox mechanisms. Does it work if you just sweat from exercise? Does that count? Yeah, that's the first question I asked Stephen. So when he presented the data at a conference, so 15 years ago, I was the first person to raise his hand and I said, Well, how about other things like sweating? He said, it doesn't matter. As long as you're sweating, you're getting rid of toxins. And doesn't

matter how you sweat. What what you're saying basically, is that the fat soluble toxins from petrochemicals and plastics and valets and BP and all the things we talked about, don't get released, not very easily. And so you can get them out of your blood but they may still have effects even if they're stored in your fat fish yes yes and and and that it's tough to get rid of them uh and you very few ways to actually get rid of them but saunas may be a way to do it yeah so i have a little uh slight variation i do on sauna so just basically you

want to sweat for at least 20 minutes vigorously. You want to make sure you're drinking plenty of fluids. My one little tweak is I recommend you put some alkalizing minerals in your sauna, in your juice. Electrolytes? Electrolytes, yeah. So some magnesium and potassium. You can use carbonate.

I prefer citrate. And what that does is it slightly alkalinizes the body, makes it easier for the cells to get rid of the toxins. And it makes it easier for them, when you urinate afterwards, makes it easier for the kidneys to get rid of the toxins as well. One of the things I heard is sort of a hack, and I don't know if it's any data on this, but a number of my patients have been juicing cilantro rather than taking chelators and have had their metal levels drop significantly. Interesting. Is there any data about this? I looked at the research on cilantro and chlorella

and things like that. There's surprisingly little actual hard human research. Yeah. So I think they should be useful. I wish I could find some stuff. I mean, I found studies here and there, but you know, I studied from Russia with, you know, 20 people, it's hard to be confident in that data. Yeah. So, so the, the other piece around this is sort of metal detoxification, which is a, it's kind of a, a sort of a rabbit hole that I think is important to go down because like, honestly, as a doctor doctor i learned nothing about this and still today three decades after i had mercury poisoning and talking about it forever it's still not on the

radar of traditional medicine and and the testing that we use is pretty much dismissed which essentially is taking a key later a biological agent biolytic lesion that binds to metals. I think chelator is from a Greek word that means claw. And we use it to then detect how much urines, how much the metals spill out in the urine and track that over time as a way of tracking therapy and treatment. And I've done tens of thousands of these tests

and it's just amazing what we find and how we treat people. For example, I found that there was a whole bunch of special forces guys we were treating at Cleveland Clinic who had chronic fatigue syndrome and all these big symptoms and the army and the military was so dismissive of them. They're like, look, these guys are not whiners.

These are Navy SEALs. These are Green Berets. These are Army Rangers. These are not guys who are kind of, you know, weak or just kind of complainers. And something's going on. And so I started asking questions. And what do you do?

Well, I'm a blast instructor. I mean, what does that mean? Well, I blow stuff up inside. I teach other guys how to blow stuff up. Like, oh, you're blowing stuff up. So that's like lead and mercury all this up in the in the blast materials and i checked them and their levels were off the chart yes and so we started to to sort of uh treat these people and there was one of them

that was reported in the new york times who has seen one of the top experts in lead in the country i think at mount sinai or or albert einstein's, one of those hospitals. And they use a bone-absorbed geometry to measure the lead in the body. And he saw the patient before and then after I treated him with chelation, with DMSA. And he was shocked because he said he'd never seen levels go down, ever. Fantastic. This is like the top lead expert in the world and they don't even know how to treat it. So, you know, I don't know why there's so much resistance to actually looking at this. It's something that should be pretty easy to validate. It's something easy to validate. You

can just, you know, measure it and track it. It's like an easy thing to do. But I think, you know, the whole process of heavy metal treatment is a thing. And I think you mentioned arsenic, you know, voiding is great. But lead and mercury and these other tabby, these don't come out on their own. And as functional medicine practitioners, it's one of the things we not just for me personally, but as a treating physician with dementia, with autism, with autoimmune diseases, with colitis, with chronic fatigue syndrome. These diseases, which really have no treatment, often get better when we do this. So can you talk about what is the safest way to do this? How do people think about learning about it and being guided to do it right?

I want to follow up on what you just said. So again, I probably, I deal with, I treat a half dozen patients a year. Okay. I'm not in primary care and I spend most of my time looking at research, but research doesn't count unless you use it in real people. And over the years, my approach to patients has changed dramatically. I pretty much don't care what disease they come with. Of course, pay attention to it. Every patient, I test their body load of toxins, I test their nutritional status, and I do the genetic analysis to see where the weaknesses are. I deal with those things. And what about the gut? Of course. Okay. But actually, I don't test the gut because I know what to do anyway. You know what to do anyway, yeah.

So anyway, I find if you get the toxin low down, nutrition up, improve the gut, so many diseases start going away. So I just, I just, we need to change how we deal with people. So going back to what you're talking about metals, huge portion of population high in metals. So for example, my wife, on my advice and the patients that I have, I have them take 250 milligrams of NAC every third night. NAC-16, it helps with the thyroid, yeah. 250 milligrams, not a lot. Remember, a lot of this I developed in Corporate Wellness

where I'd free a person, I wouldn't see them again for six months. Well, you can't use high dosages. So 250 milligrams every third night, along with 10 extra grams of fiber. I use PGX because I have a commercial relationship with them. And I just have them do that regularly, kind of forever, because it chelates out the lead, it chelates out the mercury, and it helps to rid the arsenic a little bit, not great. And now, having said that, you have to also give them a little bit of molybdenum, maybe 100 micrograms,

because the enzymes that metabolize sulfur compounds depend upon molybdenum. I personally cannot take DMSA every third night because I cannot detoxify sulfur compounds adequately. Sulfur makes me sick, okay? So just what I'm going to tell you, anybody you do this protocol on, they start complaining about GERD, about allergies, about gastritis or colitis, check them for sulfur toxicity.

Yeah. So yeah, I think I've developed very robust protocol using a whole host of compounds and food that regulate detoxification lots of fibers you said saunas also um the right supplements then for methylation you know cysteine the right minerals we talked about but also use i also use uh high fiber from binder but but i think dmsa is a very powerful chelator it It's FDA approved for lead chelation in children. And it's not really used in medicine very much at all, even in kids.

But I find it one of the most effective ways to gently remove these heavy metals and help with these chronic inflammatory or toxic conditions. Yes. I have a huge amount of data. That protocol I just described, in a year and a half, it'll drop mercury and lead over 50% without any adverse events. Amazing.

Before we close, I want to dive into a topic that I think is a broader view of the framework of toxins. So I think we can all accept that we're living in a sea of petrochemical toxins, heavy metal toxins, that we need to pay attention to it, that we need to understand how our biology works to operate with our detox systems. And I've written a lot about this. Your book is amazing, The Toxin Solution, you share a lot about this.

But it's this whole field of EMFs, right? Electromagnetic frequencies. You know, Wi-Fi, 5G, cell service. Now, I just came back from Ecuador and Patagonia where I was completely away from all of that. And I noticed that my heart rate variability doubled, that my deep sleep changed, and that I felt better and I slept better. And of course, I was on vacation, but I'm on vacation in other places and I don't have

those results. So I think there's a lot of controversy about this. It's very political, obviously, because our whole life depends on cell service and Wi-Fi, and everybody uses it all the time. What is the strength of the data that EMFs are an issue? And if it is an issue, what do we do about it? Mark, extremely good question, and I have to be honest,

I have not studied the research, I can't give a good response. What I can tell you is I've seen patients who are EMF sensitive. Well, how common that is, I don't know. So I'm sorry I don't have a good answer. Okay, okay, fair enough. I thought you, I mean, I think,

he's written literally the encyclopedia and textbook of everything, I thought he have a good answer. Okay, fair enough. I thought you, I mean, I think, he's written literally the encyclopedia and textbook of everything. I thought he might know, but. I just haven't gone through it yet. I do think it's an increasing issue. You know, I actually was living in New York for a while and I had this EMF detector. And you know, if you're in an apartment building in New York,

there's like so many wifi's, right? And so it was like, said five, high alert, get out immediately. And then I bought this Faraday cage. Essentially, it's like a net that goes over your bed. I would go in there. We couldn't make a cell call. We couldn't get Wi-Fi. And it was just basically zero. And it just makes me wonder about what this is doing to us because we are electromagnetic beings. And, you know, energetic beings. So, um... By the way, this is too early to talk about, but I'm in conversation with a doctor

who has been experimenting with metal detoxification. He finds if it flies on one of these high magnetic field things, his heavy metal excretion increases dramatically. So that tells me these fields are doing something in the body. Yeah, interesting. Okay, one last question. This is a bit controversial, but I'm going to jump in anyway. It has to do with the increasing rates of infertility. And it has to do with

increasing rates of, particularly this tract bloating in but you know sort of hermaphroditism and and um sort of ambiguous sexual genitalia in animals uh theo culber wrote a book about this called our stolen future which really impacted me it talks about this it was like a silent spring kind of book and uh and also i've been reading about different birth rates in in humans uh men and women now that they're just sort of becoming discordant from what we used to see, which is a fairly even birth rate. Now, I think there's more males or more females, I can't forget. Probably females. gender identity issues and transgender awareness that I'm wondering, it's so much now and I'm not thinking it's a bad thing if people want to change their gender. I'm just wondering if there's any

role of these environmental chemicals and their endocrine disruption in affecting the brain and affecting hormonal development and affecting fertility. Can you talk about that a little bit? Yes. So I have a 90-minute lecture just on environmental toxins and infertility. There's no question it plays a huge role. And we talked before about bisphenol A being removed. So let's talk about bisphenol A. If you look at the bisphenol A levels in a man's semen,

and you then look at their sperm count. It goes from normal sperm to low sperm, to abnormal sperm, to no sperm. In the men with the top 10% of bisphenol A in their male fluids, you might say, they have no sperm whatsoever. Wow. Now, that's bisphenol A. And guess what we just replaced bisphenol A with? Bisphenol S. Bisphenol S, near-sect tail, is about five times as bad as bisphenol A for male fertility. So we go after toxin after toxin. There's no question these toxins are destroying our fertility,

which means they're also damaging the development of the fetuses that do manage to get through the infertility problem. So gender dysphoria, it's got to be environmental toxins have to be playing a role. It's so very clear. Yeah, it's concerning. And the animal research is very clear on that. Yeah, clearly this is a big issue. But I think the perspective that you brought over the last decades of teaching us all about environmental toxins, your work is so important. I think everybody needs to check out Joe's book, The Toxin Solutions, and I'll have all your books.

Check out the textbook of natural medicine, the encyclopedia of natural medicine, so many. If you're a doctor, I have a textbook called clinical environmental medicine, and a lot of this research is in there. Yeah. So Joe, thank you so much for being on the podcast. Thank you for your work in this field. Thank you for being my teacher for so many years. Mark, thank you.

I mean, look at what you're doing to educate people. You know, I have my books inside, but they're just for doctors, man. Like you're, you're educating the whole. I just stole everything you ever wrote and redid it in my own way. Thanks for listening today. If you love this podcast, please share it with your friends and family. Leave a comment on your own best practices on how you upgrade your health and subscribe

wherever you get your podcasts and follow me on all social media channels at DrMarkHyman. And we'll see you next time on The Doctor's Pharmacy. I'm always getting questions about my favorite books, podcasts, gadgets, supplements, recipes, and lots more. Now you can have access to all of this information by signing up for my free Mark's Picks newsletter at DrHyman.com forward slash Mark's Picks. I promise I'll only email you once a week on Fridays and I'll never share your email address or send you anything else besides my recommendations. These are the things that helped me on my health journey and I hope they'll help you too. Again, that's drhyman.com. Thank you again and we'll see you next time on The Doctor's Pharmacy.

This podcast is separate from my clinical practice at the Ultra Wellness Center and my work at Cleveland Clinic and Function Health where I'm the Chief Medical Officer. This podcast is separate from my clinical practice at the Ultra Wellness Center and my work at Cleveland Clinic and Function Health, where I'm the chief medical officer. This podcast represents my opinions and my guests' opinions, and neither myself nor the podcast endorses the views or statements of my guests. This podcast is for educational purposes only. This podcast is not a substitute for professional care by a doctor or other qualified medical professional. This podcast is provided on the understanding that it does not constitute medical

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