The Dr. Hyman Show - Exclusive Dr. Hyman+ Ask a Doctor: Weight Loss, ADHD, Hormone Replacement Therapy and More

Episode Date: February 27, 2024

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Starting point is 00:00:00 Hey podcast community, Dr. Mark here. I'm so excited to offer you a seven-day free trial of my revolutionary new platform called Dr. Hyman Plus. For seven days you get special access to all the private content included in Dr. Hyman Plus entirely free. It's so easy to sign up. Just go to Apple Podcast on your phone and click try free button on the Doctors Pharmacy podcast. You'll get exclusive access to ad-free Doctors Pharmacy podcast episodes and functional medicine deep dives where a practitioner dives into topics like heart health, muscle health, insulin resistance, and more to help you understand the root cause of specific ailments and walk you through the steps to improve your health today. You'll also get access to all my Ask Mark Anything Q&As where
Starting point is 00:00:51 I answer the community's biggest health and wellness questions. Because I'm so sure you're going to love this platform, I am offering you free access to all of this content for seven days and a teaser of my brand new Ask Mark Anything episode. Head on over to the Doctors Pharmacy podcast on Apple podcast and sign up for your free trial. Okay, here we go. Hi everyone. Thank you so much for tuning in to today's episode. My name is Melanie Haraldson and I'm one of the producers of the Doctors Pharmacy Podcast. We are excited to have Dr. Elizabeth Bohm back to answer your questions this month. As many of you know, Dr. Bohm is the Medical Director of the Ultra Wellness Center in Lenox, Massachusetts, and has done several deep dives for our community as well as our AMA episodes.
Starting point is 00:01:41 So Dr. Bohm, we are so excited to have you back for this month's episode. Welcome. Thank you, Melanie. It's great to be with you and with all the listeners. So thanks for having me. Thanks. So we've collected our community's top questions and we are here to ask you anything. So let's get started with the first question. So this comes from a community member who went into premature ovarian failure at the age of 34 after going through a few extremely stressful and traumatic events. She's 42 years old now. She's been taking HRT for the past four and a half years and, um, estrogel, a low dose, one pump a day and progesterone. Is there any concern about her being on HRT versus BHRT? And I don't know if you want to kind of explain the difference between the two, but just if
Starting point is 00:02:29 there's any concern about her being on HRT versus BHRT. And then is there any concern about her being on HRT long-term since she's in her early 40s? Would it be safe to continue taking it for an extended period of time? And are there any long-term risks associated with it? Yeah. So HRT is short for hormone replacement therapy. And BHRT is short for bioidentical hormone replacement therapy. But there's a lot of hormone replacement therapy, even ones that a lot of hormone replacement therapy, even ones that you can get from a conventional pharmacy
Starting point is 00:03:08 that are officially bioidentical. So I'm not sure exactly what progesterone she's on, but her Estrogel is actually an estradiol, which means it is bioidentical. It's bioidentical to what your own body makes. And so as that's as opposed to some of the hormones that were popular a bunch of years ago, Premarin, Provera, that was not bioidentical to your own body's estrogen. It came from pregnant horse's urine and it was a different structure. So many of the hormones out there, whether they're patches or creams are considered bioidentical.
Starting point is 00:03:47 And, and, and as I said, you even, you can get them compounded at a compounding pharmacy, but also they're available at a lot of regular pharmacies, probably the estrogel she's on, she's getting from a regular pharmacy and it is, as I said, an estradiol. So it is bioidentical to what her own body makes. I hope that helps sort of clear that one up because it's a little confusing. But in this situation, because she went through premature ovarian failure at a young age, it does make sense for her to be on some hormone therapy until she reaches the average age that a woman goes through menopause. So the
Starting point is 00:04:25 average woman goes into menopause or stops having their period between the age of 45 and 55. So it's great for her to be on hormone therapy. And this is, you know, at least the estradiol is a bioidentical until sometime within that age range. And that's to prevent any of the risks from the deficiency of estrogen that can occur when you go into menopause at an early age. So and then and that's largely bone density, right? So so I don't have concerns, of course, with any therapy, including hormone therapy, you know, you're always weighing the risks and the benefits, right? But this seems like a pretty good treatment for her to be on at this period of time.
Starting point is 00:05:12 A follow-up question that she has is, if she wants to focus on losing fat, particularly in the midsection, is it better to work out strength training in a fasted state in the morning or after a small meal? Any other advice on losing belly fat? Yeah. So exercise and strength training is a great way to lose belly fat. Exercise and strength training improves your insulin sensitivity. And when you have insulin resistance, the body likes to put weight around the belly. So, so great job with getting the strength training in. And what I will say is there's been a lot of research to show that when you do your exercise first thing in the morning, you're more likely to
Starting point is 00:05:56 do it. So, um, if, if this is, if morning exercise time is a good time for her, then, you know, uh, we really just want to do it, right? Just do it. And, um, and, and I, and I, and one of the things I get concerned about is too many rules. So sometimes when there's a lot of rules in play about timing of food and exercise and all of that, sometimes that gets people confused and then they just don't exercise. So first of all, the most important thing is to get the exercise in. And if the morning is the best time for this person, morning is great. Not everybody feels comfortable eating in the morning. Some people get nauseous or they're just not hungry.
Starting point is 00:06:36 And so I think that exercising and doing strength training in the morning, either fasting or with a small meal beforehand, both are great. There is some research to suggest that that small meal before strength training in the morning may help us put on more lean muscle mass. And the reason is because you're less likely to break down your own lean muscle mass if you're in a fed state versus a fasted state. So people who have fasted all night long, of course, and then they start strength training first thing in the morning, there is a potential risk that in order to have the nutrition and the calories to exercise, they might be burning up some of their own lean muscle mass. So that's a potential concern. But so if somebody wants to have a small meal before exercise, a great thing to do is 200 to 300 calories with about 15 grams of protein. And so that may be like a banana and some nut butter or a small smoothie. And those are things that people might enjoy having first thing in the morning. But, you know, honestly, just exercising in the morning is great.
Starting point is 00:07:47 And you're doing a good thing for your body in terms of helping prevent the weight gain around the belly. Okay. Thank you so much for that. So the next question is, do you have any thoughts on a postmenopausal female struggling with ADHD symptoms? Focus, task completion, and horrendous anxiety. Are there any supplements that would be helpful? Any thoughts on taking both a stimulant, Vyvanse, and HRT? Are there any dangerous to be aware of? So I guess I have a few questions. So I would wonder when did these symptoms start? So did they start when this woman went into perimenopause or menopause or have they been lifelong symptoms, right? So is the attention issues and anxiety
Starting point is 00:08:33 worse now that this woman has gone through menopause? And how long has this woman, how long has it been since she had her last period? Those sorts of things help me determine what's going on and why there may be this increased issue with attention and anxiety. So definitely hormone shifts can be at play here. So we do think about hormones, especially if it seems like the timing went through menopause and then these things got a lot worse. But there's a lot of other things we can really work on. So I wonder about her protein intake.
Starting point is 00:09:11 Is she getting protein at every meal? So both animal and vegetable protein, beans, legumes, nuts, seeds, soy, eggs, fish, chicken, beef, protein at each meal to help balance blood sugar and help with the attention and focus. Also focus on making sure you're getting enough omega-3 fats, right? Those omega-3 fats really help brain health. So, you know, your fish oil, your fatty fish, your ground flaxseed, really wonderful for omega-3 fats, lowering inflammation and brain health. I'd make sure that she had some basic labs done. You know, what's her thyroid like?
Starting point is 00:09:50 What's her iron like? Her cortisol, you know, maybe even do a sleep study to rule out sleep apnea because we know that sleep apnea, where somebody has these apneic episodes at night and they stop breathing, that actually can be a major contributor to having problems with attention and even anxiety at night. So, um, you know, a sleep study can be a really helpful thing to look at if somebody is really feeling poorly in that area. Um, progesterone is a hormone and progesterone, when you take it orally can really help with anxiety and sleep. And so that may be a hormone that you consider, you know, in this situation, or maybe even a comprehensive bioidentical hormone replacement. In terms of supplements.
Starting point is 00:10:41 I think I was just going to say, so I, this, so this question is from the same individual as the previous one. I just kind of, um, yeah. So we just kind of broke it up to make, cause they're kind of separate questions. So I think the same thing applies here where she is taking, um, the S the estradiol or the, the estrogel along with the progesterone. Ah, okay. Okay. So I guess I'd be curious as to what type of progesterone they're using and if it's oral or transdermal and if it's transdermal, meaning through the skin, oral might be more helpful for the anxiety. And you could also make sure you got the progesterone compounded in a bioidentical progesterone. Sometimes that helps more than other forms of progesterone. Okay.
Starting point is 00:11:37 Yeah. In terms of, thank you, that's helpful. In terms of supplements, there are amino acid supplements that we often use for focus. So they are combinations of amino acids that help with making neurotransmitters that help with focus. So they will have tyrosine in it, tryptophan, taurine, and they can be very helpful if somebody's not on like an antidepressant or if they're not taking Vyvanse. So if they're if they're looking more for a supplement treatment, those can be really helpful. I also use a lot of magnesium, magnesium glycinate or magnesium threonate to help with calming and anxiety. And maca can be also really helpful as well. But I guess I'm curious as to the timing of
Starting point is 00:12:28 the attention issues and if they're really related to menopause, or it makes me think that something else may be going on if these issues weren't lifelong. That makes sense. And then is there any dangers to be aware of if they're taking, like say both Vyvanse and HRT or that's not necessarily together. Um, not necessarily together, you know. All right. Awesome. Thank you. Uh, so kind of following along that same line of, um, menopause. So this question comes from a community member who had surgical menopause in 2021. She's currently 56 years old.
Starting point is 00:13:08 She's currently experiencing the following symptoms. No energy, no sex drive, mood swings and hot flashes. What is your advice for addressing her symptoms? Should she look into taking BHRT? Right. So, you know, 56 or when you've recently gone into menopause is actually the time you want to think about hormone therapy. So you don't want to wait too long after after going into menopause. The research shows that hormone therapy is the most helpful when somebody is perimenopause. So when their periods are irregular and they're starting to go into the change of hormones, as well as an early menopause. So typically if we're going to
Starting point is 00:13:52 start hormone therapy, the general recommendations are to start before the age of 60. So this is a great time to think about it. And hormone therapy definitely can help with hot flashes, especially. That's kind of like they can definitely help for that as well. And so this is a time to look at the risks and benefits of hormone therapy. But the other thing that I think is really important is that we step back and we look at this person as a whole. And that's really what we do in functional medicine. We get a really detailed history of what their timeline is, what their life experience is, what are their personalized lifestyle factors like.
Starting point is 00:14:37 You want to really focus on the bottom of the matrix we talk about in functional medicine all the time, because when you support those personalized lifestyle factors, that really helps support all the hormones in the body. So, you know, that is making sure somebody is getting adequate sleep, making sure they're doing daily and regular exercise, making sure they're making, getting the right food choices, balancing their blood sugar, getting enough nutrition, getting the right nutrients, avoiding too much alcohol, right? All those things we know that can change how we're feeling significantly. Doing some stress reduction techniques every day and having good relationships and networks. All of these things really support all of the hormones in the body. They also support your adrenal glands. And remember, we have these two
Starting point is 00:15:32 adrenal glands. They sit up on top of our kidneys and the adrenal glands are these glands that help us with all sorts of things in the body. So the adrenal glands secrete cortisol and they help us with managing stress. And when you have good working adrenal glands, that process of going into menopause is often smoother. And so focusing on those adrenal glands and supporting the adrenal glands and what is called the HPA access, right? That of supporting that part of the body will help this process. And so really good research to show that 15 minutes of breathing exercises twice a day
Starting point is 00:16:12 helps with all these symptoms. They can cut hot flashes in half, both the amount of hot flashes and the severity. They can, those breathing exercises can help with sleep and they can help with mood and irritability. And the other thing I find really helpful for a lot of women in this time frame is acupuncture. Acupuncture is a great modality that can help support hormones during this transition. And then we sometimes use supplements that support the adrenal glands. They'll include things like adaptogens, which include rhodiola and ashwagandha, B vitamins that have some methylated folate in it,
Starting point is 00:16:51 and maca. All of those things can be really supportive as well as hormone therapy, or instead of, depending on where that person's coming from and their individual risks and benefits and what their goals are. Well, I hope you enjoyed that teaser of exclusive content that you get every single month with Dr. Hyman Plus. If you want to listen to the full episode and get access to ad-free podcast episodes, plus Ask Mark Anything episodes, plus monthly functional deep dive episodes. I guess that's why we call it Dr. Iman Plus. Then head on over to The Doctor's Pharmacy on Apple Podcasts and sign up for your seven-day free trial. This podcast is separate from my clinical practice at the Ultra Wellness Center,
Starting point is 00:17:40 my work at Cleveland Clinic and Function Health, where I'm the Chief Medical Officer. This podcast represents my opinions and my guests' opinions. Neither myself nor the podcast endorses the views or statements of my guests. This podcast is for educational purposes only. It's not a substitute for professional care by a doctor or other qualified medical professional. This podcast is provided on the understanding that it does not constitute medical or other professional advice or services. If you're looking for help in your journey, seek out a qualified medical practitioner now. If you're looking for a functional medicine practitioner, you can visit ifm.org and search their Find a Practitioner database.
Starting point is 00:18:13 It's important that you have someone in your corner who is trained, who's a licensed healthcare practitioner, and can help you make changes, especially when it comes to your health.

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