The Dr. Hyman Show - Exclusive Dr. Hyman+ Ask Mark Anything: Kidney Issues, Benign Prostatic Hyperplasia, And More
Episode Date: April 25, 2023Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more ent...irely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at plus@drhyman.com with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.
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Hey podcast community, Dr. Mark here. I'm so excited to offer you a seven-day free trial
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Okay, here we go.
Hi, everyone. Welcome to another episode of Ask Mark Anything. My name is Harshal Perth,
and I'm the Dr. Hyman Plus community manager, and I'm joined by Darcy Gross. Hi, Darcy. Hi. Darcy is one of the producers of
Longevity Roadmap docuseries. And of course, we're here with our expert, Dr. Mark Hyman.
Hi, Dr. Hyman. Hi, everybody. Thanks for being here today. So let's go ahead and get started
and ask Mark anything. So our first question is, does hyperbaric
oxygen therapy have a place in functional medicine? And if so, would it have positive
effects on autoimmune disorders affecting the skin? Oh, that's a great question. Well,
there's sort of two questions. One is hyperbaric oxygen in general, and two is what conditions
does it treat? And I think this is a really powerful therapy. I really like therapies that are using kind of biological
influences to regulate our body systems. And, you know, medications often have side effects,
they have unintended consequences, they may help one thing, they may cause another problem, but treatments that are
kind of using biological substances like oxygen, for example, can be very effective. And basically,
for those of you who don't know, hyperbaric oxygen is oxygen under pressure. It was developed when
people were scuba diving. When they came up too fast, they'd get nitrogen in their blood,
and they had to kind of quickly put them back down under the water, essentially by putting them under two atmospheres or more pressure, which is like 66 feet under the water.
So that basically was used to treat what we call the bends. However, it's incredibly helpful for
many, many conditions in medicine, from wound healing, which it's approved for. If you have diabetic ulcers, if you're having poor wound healing, it can drive circulation, oxygen into
the tissues and really help. It's also being used in neurologic conditions. So people who have
a stroke, I've had many patients who had stroke who use it and helps bring back blood flow to
the brain. People with Alzheimer's, people with Parkinson's, kids with autism, cerebral palsy. It's really quite an interesting
therapy for helping to heal the brain. It also is incredibly helpful in infections. People,
for example, have Lyme disease, chronic fatigue syndrome, autoimmune diseases, for sure,
can be influenced by improving the body's oxygenation and in using
this as a stimulation to help repair and heal the body. Now it's a bit of a stress. It's what we
call a hormetic stress. I write about it in my book, you know, forever. It's a hormetic stress
means something that actually is sort of a stress. It doesn't kill you, but it makes you stronger.
And, you know, being under, you know,
66 feet of water is like a lot of pressure on your body, high oxygen concentration, our bodies
aren't used to, and it's kind of a stress, but it kicks into gear your body's own repair and
healing systems. So it increases stem cell production, it increases your antioxidant
systems, it reduces inflammation, it helps to actually increase the ability of the body to
sort of repair and heal and kills infections because bugs don't like high levels of oxygen,
sort of like Lyme disease, for example. And it also increases, you know, one study I wrote about
in the book, which is very impressive from Israel, it increases the telomere length. So it increases
telomeres more than anything else known, and there are a lot of things that actually increase
telomere length, lifestyle therapies, exercise, vitamins, so forth. But what this does is actually
increases telomere length more than anything else. It also kills zombie cells, which are
another part of the aging process where our cells turn into these zombie cells that don't die, that spew out inflammation everywhere. And that actually is reducing those that we call senescent
or zombie cells, which are very hard to kill. So there's a lot of things we're just still
learning about. I personally used it when I had, you know, mold toxicity as a really helped me
clear my brain and also helps with post-COVID syndrome. People have
brain fog and cognitive issues around COVID. It can be extremely helpful. So I think it plays a
really important role in medicine. Hyperbaric medicine is really important. It's not,
unfortunately, covered for most of the indications that I just mentioned. It is covered for things
like wound healing and certain other medical indications, but, but typically there are,
are in traditional medicine hospitals where they have these, they're not used for kind of
off label indications. And so you have to go to other hyperbaric centers and they're,
they're all around. It's not, it's not cheap. You know, it is kind of expensive, but
if you have something serious, it can be a really helpful, helpful therapy.
Yeah, that's so helpful.
Thank you for all that information on that.
Darcy, over to you for the next one.
All right.
So our next question is, what is benign prostatic hyperplasia or VPH and how to treat it?
Great question.
So, you know, most people understand that people get prostate issues when they get older.
If they're guys, obviously women don't have prostates.
So it's an enlargement of the prostate gland and can be an overall enlargement of the whole
gland or just an enlargement of the kind of area in the middle that goes around the urethra,
the tube that empties your bladder.
And when that happens, it sort of squeezes
the exit from your bladder and you can get into trouble where you can't pee. And so the symptoms
typically are getting up frequently at night, urgency, like I got to go now, trouble getting
started peeing. So you might not be able to get going. You feel like you got to pee, but you can't
actually start to pee. You might get a split stream of your urine so it looks kind of funny all those are signs that
there may be enlargement of your prostate now there are treatments for it medications
plomax there's herbs for it saw palmetto can be very effective which i've used
it also uh and there are many other compounds that can be used. One of the products is prostate.
I think it's 5LX, which you can get on our online store.
And it has a combination of herbs and other compounds that can be effective.
It also can be treated with surgical techniques, with laser, with more sort of advanced radio frequency techniques.
So there's ways to treat it to help men who get, you know, problems. But it's one of those things for guys where it's like, oh boy, you know,
this is really impairing my lifestyle. I can't drive in a car without, you know, I can't sit
in a plane. I can't like, it's just, it's hard when you have to go that much. So the question
is what's causing it? And as a functional medicine doctor, I'm always like asking why,
why do people get BPH? Why do people have enlarged prostates?
And this is a phenomenon that doesn't necessarily affect everybody.
So a lot of it has to do with lifestyle.
So highly sort of Americanized diet that's full of starch and sugar driving insulin resistance
is probably, you know, the biggest cause.
Alcohol can be a factor.
A lot of food atoms can irritate and make you kind of go
more often, but it's a really common condition for guys as they get older and most have to sort
of manage it a little bit. I'm sort of lucky I'm 63. I'm still, I'm okay. I remember my dad used to,
it's a funny story where we were in a train station or I think we're on a train and he'd
like had to go and it was like a big line and literally like could not handle.
I mean, he ran and peed in the sink because it was like, it was so uncomfortable.
So it's a kind of a nice memory.
I have my dad in Barcelona.
I think so, but it's not a fun thing when you have it.
Yeah.
And we have a follow-up question, which is, is there a connection between high estrogen and BPH?
Not necessarily. There is, you know, a hormone that's made, it's called dihydrotestosterone,
which is a very stimulating version of testosterone that can cause an enlarged prostate. So we can
measure dihydrotestosterone in men. We can see that this may go up. And there are ways to modulate it. One
of the ways is using a 5-alpha-reductase inhibitor, which is the natural version of
salpalmetto. Or you can use some of the drugs like finasteride or, I forget the name of it.
It's a, that's the name of the, the, the brand, the generic name.
I don't remember the brand name of the drug. Propecia is used for hair loss. It's the same
mechanism. So it blocks testosterone conversion from testosterone to dihydrotestosterone, which
reduces the sort of stimulation of the prostate. All right. That's super helpful. Thank you.
And over to Herschel for our next question.
So our next question is about a supplement. And of course, there's so many supplements out there.
Just trying to get a handle on which ones everybody needs. So this one is about berberine.
What is berberine used for and who can benefit from using berberine? Are there any pros and
cons to it? And does it have any effect or beneficial role on gut health? Yeah. So, you know,
Burberry and I've used for years and years in my practice. It's a, it's from a plant from various
kinds of plants, like including golden seal, Oregon grape, but, and in various other compounds,
and it's kind of, it's kind of a yellowy substance and it's, it's incredibly helpful for people with
cardiometabolic issues with,
it's an antimicrobial. So I've used it sort of to treat, you know, overgrowth of bacteria,
the gut and dysbiosis is incredibly helpful for people with diabetes, high cholesterol,
high blood pressure, and liver issues. So I think, I think I, I find it a really important
compound when you're treating people with cardiometabolic disease to help, you know, you know,
and really kind of improve their overall metabolic health.
So it's part of my toolkit for people with elevated cholesterol,
blood sugar, high blood pressure.
PCOS can be very effective for that as well.
Women have PCOS people with high triglycerides also.
So I find it a really useful herb. I use one called CM core by orthomolecular sciences,
but there's a lot of them out there. And I think it's not like a panacea, but I think it's a good
tool in the toolkit. All right. Super helpful for that. Thank you. Darcy, over to you for the next
one. All right. I'm just going to read it word for word here. What could be the possible causes
of having a urine test that came back positive for having red blood cells in it?
Yeah. So, you know, red cells in your urine are not uncommon. They can come from a bladder
infection. It can be caused by something going on in your prostate, like a prostatitis.
If you're a female, it can be from a urinary tract infection, but it can also be from something more
serious like autoimmune disease in your kidney or a tumor in your bladder or your kidney or
maybe even a stone. So we basically, you know, take it very
seriously. We want to see what's causing the blood. Also for women, if they're having their
period, you can kind of get a contaminated specimen. But basically it's a warning sign
that something's wrong and they need to go digging. And then you can do various further
testing such as, you know, a cystoscopy, which puts a scope up your urethra
into your bladder. You can do, you know, imaging of ultrasounds, MRIs, you know, intravenous
polygram, which is a way of looking at the whole bladder, kidneys, urethra, ureter combination.
So I think it's a serious thing. So you want to check it out.
Yeah. And I have a follow-up question to that, which is, can you speak to the best way to support
kidney health?
Let's just say that's kind of what's causing our issue is kidney issues.
I mean, listen, I mean, you know, it's important to, well, first of all, it's like, it's just
trying to stay hydrated because your kidneys are basically flushing out toxins.
So you want to stay hydrated as a way to keep your kidneys healthy,
but there are a lot of things that cause kidney damage.
And, and I sort of break them down into things like
sort of metabolic issues,
which would be related to insulin resistance, pre-diabetes, diabetes,
high blood pressure, and all that drives damage
to the kidneys. So the biggest cause of kidney failure is basically insulin resistance, which we
talked about over and over and over on the podcast. And, you know, I've written about for years,
it is the central thing driving aging and almost everything. So sugar and starch, I know you're
tired of hearing me say this, but flour and sugar are the thing that turns the sugar in your body quickly is driving high insulin levels, which
creates a cascade that leads to inflammation, leads to insulin resistance, it leads to high
blood pressure and all these things and ultimately diabetes, which ultimately damage your kidneys.
So that's probably the biggest thing. Other things that can be factors are kidney stones. So you want to make sure you stay well hydrated because you want to prevent kidney
stones. Oxalates can be a problem for people if they're, you know, so genetically predisposed to
kidney stones. So they may not want to eat too much spinach or beets or beet greens particularly.
And then there are also ways that, you know, you sort of can think about autoimmune kidney disease.
You know, I've had many, you know, many common autoimmune kidney disease like IgE nephropathy
can be caused by leaky gut. And so keeping your gut healthy is really important.
Gluten, I've had patients who really had serious gluten issues, celiac disease,
but it manifested as a kidney failure. So you have to kind of keep an eye on
this. Also, one of the things people don't realize is that if you take a lot of Advil or Aleve or any
of those non-steroidal anti-inflammatory drugs, they do tend to kind of be hard on the kidneys
and can cause kidney failure. Alonzo Mourning was a basketball player who had a lot of injuries and
this and that. He was always taking tons of Advil and ended up having kidney failure, like, in his 30s. So it's not,
it's not, you know, a huge risk. But if you're taking this stuff on a regular basis, you have
to be careful. I have a patient right now who's, you know, been on anti-inflammatories for a long
time, and his kidneys are not doing great. So I think we just have to be smart about our lifestyle
and diet and all
the things we just talked about. Well, I hope you enjoyed that teaser of exclusive content that you
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Hyman Plus, then head on over to the doctor's pharmacy on Apple podcast and sign up for your
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