The Dr. Hyman Show - House Call Highlight: Acne, Weight Gain, Facial Hair, Hair Loss, Infertility: Is PCOS The Cause? with Dr. Elizabeth Boham

Episode Date: May 17, 2021

House Call Highlight: House Call Highlight: Acne, Weight Gain, Facial Hair, Hair Loss, Infertility: Is PCOS The Cause? | This episode is sponsored by HigherDOSE and Rupa Health PCOS, or polycystic ova...rian syndrome, affects between 5 to 10 percent of all women. PCOS symptoms include irregular or heavy periods, acne, facial hair, scalp hair loss, increased belly fat, and increased levels of testosterone. It is also strongly correlated with infertility. While conventional medicine typically views PCOS as a gynecological issue, it is actually commonly driven by things such as diet, environmental toxins, genetics, and more. In this episode, Dr. Hyman sits down with Dr. Elizabeth Boham to discuss the Functional Medicine approach to treating patients with PCOS. They delve into topics including the relationship between PCOS and insulin resistance, gut health, and much more. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing, she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dr. Boham has contributed to many articles and wrote the latest chapter on Obesity for the Rankel Textbook of Family Medicine. She is part of the faculty of the Institute for Functional Medicine and has been featured on the Dr. Oz show and in a variety of publications and media including Huffington Post, The Chalkboard Magazine, and Experience Life. Her DVD Breast Wellness: Tools to Prevent and Heal from Breast Cancer explores the Functional Medicine approach to keeping your breasts and whole body well. This episode is sponsored by HigherDOSE and Rupa Health. The Infrared Sauna Blanket from HigherDOSE gives you all the benefits of infrared in an easy-to-use, portable blanket at a much lower cost than a stand-alone sauna. HigherDOSE is offering my community an exclusive discount of $75 off, with promo code FARMACY75 at higherdose.com.  Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com.  In this conversation, Dr. Hyman and Dr. Boham discuss: The continuum of symptoms that can occur with PCOS The role that insulin and insulin resistance plays in PCOS How conventional medicine treats PCOS Common drivers of PCOS, including diet, environmental toxins, genetics, and more The hormone/gut microbiome connection The Functional Medicine approach to treating and testing for PCOS How dairy affects hormones and can cause acne and digestion problems PCOS and infertility Additional Resources The Fertility Diet: Groundbreaking Research Reveals Natural Ways to Boost Ovulation and Improve Your Chances of Getting Pregnant https://www.amazon.com/Fertility-Diet-Groundbreaking-Research-Ovulation/dp/0071627103 A Simple Diet Experiment That May Solve Most Of Your Health Issues with Lisa Dreher https://drhyman.com/blog/2020/08/22/podcast-hc24/ Clara’s Case Study: Overcoming Infertility https://www.ultrawellnesscenter.com/2018/09/05/claras-case-study-overcoming-infertility/ Why Most Everything We Were Told About Dairy Is Wrong https://drhyman.com/blog/2020/08/19/podcast-ep131/

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Starting point is 00:00:00 Hi, I'm Kea Perot at one of the producers of The Doctor's Pharmacy. Millions of women worldwide are affected by PCOS or polycystic ovarian syndrome. So it's no surprise that this episode with Dr. Hyman recorded with Dr. Elizabeth Boham is one of our most listened to episodes of all time in our House Call series. We're re-airing this important conversation today to help bring awareness and education to this pervasive issue. We hope you will listen or re-listen and share this episode with your friends and family to help spread the word. Now, on to the episode. Hey everyone, it's Dr. Mark. You probably heard me talk about how much I love infrared saunas on the podcast. They've been linked to
Starting point is 00:00:40 many different benefits like better muscle recovery, calming of the nervous system, improved circulation, and even activation of the immune system to support protection and healing. Saunas also promote the release of feel-good endorphins that give you that blissed-out feeling and give your skin a healthy glow. I think it's fascinating that so many cultures around the world have some kind of history of sauna use, and I don't think it's a mistake. People have recognized for centuries that heat exposure and sweating has therapeutic effects and now it's easier than ever to take advantage of that ancient wisdom on a regular basis. I know not everyone has the room or the budget to have their own sauna at home so I was really excited to learn about infrared sauna blankets from Higher Dose. It gives you all the benefits of infrared and easy to use portable blanket at a much lower cost than a standalone sauna. The blanket is so cool. It has a layer of amethyst to deepen the
Starting point is 00:01:30 infrared benefits, a tourmaline layer to generate negative ions, and a layer of clay to balance heat and a charcoal layer to bind pollutants as you detox. If you don't have the budget or space for a full-size sauna, this is an amazing and less expensive option to up-level your wellness routine. Higher Dose is offering my community an exclusive discount of $75 off with the promo code PHARMACY75 at higherdose.com. That's higherdose.com with the code PHARMACY75. I know a lot of you out there are practitioners like me helping patients heal using real food and functional medicine as your framework for getting to the root cause. What's critical to understanding what each individual person and body needs is testing, which is why I'm excited to tell you about Rupa Health. Looking at hormones,
Starting point is 00:02:16 organic acids, nutrient levels, inflammatory factors, gut bacteria, and so many other internal variables can help us find the most effective path to optimize health and reverse disease. But up till now, that meant you were usually ordering tests for one patient from multiple labs. And I'm sure many of you can relate how time-consuming this process was, and then it could all feel like a lot of work to keep track of. Now there's Rupa Health, a place for functional medicine practitioners to access more than 2,000 specialty labs from over 20 labs like Dutch, Fibrin America, Genova, Great Plains, and more. Rupa Health helps provide a significantly better patient experience, and it's 90% faster, letting you simplify the
Starting point is 00:02:57 entire process of getting the functional medicine lab tests you need and giving you more time to focus on patients. This is really a much-ne in functional medicine space and I'm so excited about it. It means better service for you and your patients. You can check it out and look at a free live demo with a Q&A or create an account at rupahealth.com. That's r-u-p-a-health.com. Now let's get back to this week's episode of The Doctor's Pharmacy. Welcome to The Doctor's Pharmacy. I'm Dr. Mark Hyman. That's pharmacy with an F, F-A-R-M-A-C-Y, a place for conversations that matter. And today's conversation is going to matter a lot because it's a special house call episode with Dr. Elizabeth Oham talking about something called PCOS or polycystic ovarian syndrome, which is a super
Starting point is 00:03:45 common affliction that affects women that causes all sorts of misery from infertility to acne to facial hair to loss of hair on their head and weird periods. And it's just a miserable problem that affects millions and millions of women and traditional medicine just doesn't do a great job at this so we're gonna get into it today and talk about this problem so welcome welcome Liz thank you mark it's great to be with you all right well let's get into it because this is such a common problem how many people does it affect it's amazing five to ten percent of women are impacted by PCOS.
Starting point is 00:04:25 5% to 10% of women. That's a lot of women. I mean, listen, if half the population of America is 330 million, if that's the population, half of that's like 165 million. And 10% of that's like 16 million people. That's a lot of people. Yeah. And you know, it is PCOS or polycystic ovarian syndrome is a syndrome that, that is, um, involves irregular periods or not having any periods and
Starting point is 00:04:53 androgen excess or changes in your hormone balance, but it is a syndrome. So that means that there's a continuum where some people have all aspects of PCOS and some people just have some aspects of PCOS. And we can talk more about that. But so there may even be more than this, you know, that we're not even picking up. It's quite common. And it's definitely something we're thinking about all the time when somebody's coming in and complaining about irregular periods or not having had their period for a bunch of months, you know, a young woman that should be having regular, you know, periods.
Starting point is 00:05:30 And then you're really heavy periods, they can miss periods, they get life periods. What are the other symptoms that are pretty common? Yeah. So we see hertutism, which is the growth of hair. It sounds terrible. The growth of hair where women don't want to have it. So on their lip, on their chin, on their abdomen, like in their belly area. So the hair is growing where they don't want to have it.
Starting point is 00:05:54 And then they may have hair loss where they want to have hair. So they may have some male pattern hair loss. They get acne. And typically- So basically, they're losing hair where they don't want to lose it. And they're getting hair where they get acne and typically so basically they're losing hair where they don't want to lose it and they're getting hair where they don't want it and it's because of these high levels of male hormones yes like DHEA and testosterone then end up causing basically this male appearance
Starting point is 00:06:18 almost yeah they're there their hair their hair growth shifts because their hormone shift and so you see the bearded women in the circus that's what this is right yes well they might they some of them may have had some other things going on too to an extreme right but um but yes in general yeah this is you know you're you're starting to grow hair where you don't want it and and not having good hair where you on the top of your head where you want it and all because all because there's been a real shift in your hormone balance in your body and so when you check when we actually check we see high levels like you mentioned of that dhea in the blood we may see high testosterone
Starting point is 00:06:56 levels or high free testosterone levels and um so so those are some of the biomarkers that will show up when you look yeah and you also you also get acne, bad acne. Bad acne. Yeah. And a lot of times like in the lower jaw area, acne and sometimes cystic acne. So and then they'll often gain weight. Now, not everybody with PCOS is overweight. There's a lot of women, and we can even talk more about that today. There's a lot of women who don't have the obesity part of it, and they're
Starting point is 00:07:36 just dealing with irregular periods. But for a good portion of women with PCOS, they gain weight because of the high levels of insulin that are going on. So, you know, if they have high levels of insulin floating around, so when with PCOS, typically, there is high levels of insulin. And we've talked about insulin so many times on this podcast, and you've talked about it many times, you know, but that insulin is that hormone that helps us balance our blood sugar. So you eat a meal, the body makes insulin. That insulin tells your body to take your food and get it into your muscles so it can be used for energy.
Starting point is 00:08:11 And what happens when somebody has insulin resistance is their body's not listening to that insulin as well. And they've got high levels of insulin. And that high level of insulin will cause people to gain weight around the belly. And so we often see with PCOS that weight gain around the belly that belly weight yeah so this sounds like a miserable condition you get pimples you lose hair on your head you grow a beard you are infertile your periods are all over the place um this just sounds terrible. And traditional medicine has very kind of weird approach to it. Because the way I think about it is that it's called polycystic ovarian syndrome,
Starting point is 00:08:54 which makes people think it's a gynecological problem, but it's actually a dietary problem. Right. Right. It's often a dietary problem. And it's not always dietary, and you know it's not it's not always dietary which is so interesting right because we're you know we're learning about how um toxins from the environment like bpa and plastics and we were learning about the microbiome and how that can be a trigger um so there are other and there's so toxins and and and dysbiosis or imbalance in the microbiome are common things that we see.
Starting point is 00:09:28 But toxins can cause insulin resistance. Absolutely. And the microbiome imbalances can cause insulin resistance and prediabetes. So it's all connected. It's all connected. And you're right. And a huge portion of people, it's dietary as well. But I think it's important to remember it's dietary as well, you know, where they're, but I think it's important to remember,
Starting point is 00:09:46 it's not always that, right? But there's a huge portion of people where they're just eating too many carbohydrates, too many refined and processed carbohydrates for their body. So, you know, or for anybody's body, but those high levels of refined and processed carbohydrates really can be a trigger for this insulin resistance and weight gain. And then that insulin resistance shifts the hormone balance, and then you get this imbalance in hormones, and you get the high androgens or testosterone and DHEA, and then the periods get irregular. But interestingly, as a syndrome it can it can be it's important that we pay attention to that individual person because it's very different you know you may have 10 women in a room with pcos and you may have 10 really different reasons for why they have pcos that goes to really not all the
Starting point is 00:10:38 same yes it's really an interesting aspect for for functional medicine right i mean that just speaks to the whole approach of functional medicine, which is because you know the name of your disease, it doesn't mean it was wrong with you, right? Absolutely. It's just a description of the symptoms, but not the cause. And so functional medicine is about the cause. It's about why, not what. Not what disease you have PCOS, but why do you have that, right? And traditional medicine, the symptoms are treated symptomatically. So what are the traditional treatments that you see regular doctors giving for PCOS?
Starting point is 00:11:08 Yeah, so often women will be placed on birth control pills because if they're having irregular periods or they're skipping their period, many times the physician will put them on birth control pills because it will regulate their cycle. They'll put them maybe on metformin because metformin improves insulin sensitivity. It's a diabetes drug. Yeah. And then that can many times help with the weight gain. It sometimes helps with the
Starting point is 00:11:35 acne and the hair growth or hair loss. And they'll often put them on spironolactone, which is another medication that helps with balancing the hormones and can help with some of the symptoms. It's a diuretic and it just blocks the conversion of testosterone to the kind that really causes the hair loss called DHT. But it's really fascinating. But it really doesn't speak to addressing the root causes. So from a functional medicine perspective, what are the root causes for PCOS and how do we start to deal with these?
Starting point is 00:12:04 Yeah. So, you know, as you mentioned already, diet is huge. Diet has a huge impact when somebody's eating too many of the refined and processed carbs, too much sugar, too many of those coffee drinks with sugar in it, you know, juices, sodas, refined and processed oatmeal, you know, cereals, and, you know, pastas and breads and muffins and those foods that we've been grabbing too much of for some people with some genetics that can really throw off this whole system in their body. Another big common area are toxins. I see this a lot. I see a lot of what I think is toxin related. We know genetics plays a huge role here. We also know that when what women are exposed to
Starting point is 00:12:53 as a fetus, when what has happening to their mom is really when their mom's pregnant with them, that really impacts their hormone balance and their metabolism later in life. So what the mom's eating, she's at Dunkin' Donuts all day and- What's fascinating with- Eating the frappa mocha latte, what is, you know, all day long with more sugar than three cans of Coke. I mean, yeah, people don't realize that.
Starting point is 00:13:22 Yeah. So when they're pregnant with their baby, it's really important that they're paying attention to what they're eating because if they're gaining too much weight or eating too many refined carbs or not gaining enough weight, it's kind of interesting. So if they're not gaining enough weight or they're gaining way too much weight or they're eating too many refined and processed carbs and sugars, that really throws off the fetus, that baby's metabolism. And so, you know, sometimes, you know, we tell our patients, you can just blame it on
Starting point is 00:13:54 your mom. They call it epigenetics, which, you know, the genes get tagged and messages of, you know, Jeff Bland's called the book of life. And where the bookmarks are in the book of Life, you've got this whole genetic code, but not all of it gets read. But you can bookmark different aspects of it depending on what exposures you've had. And we know this from lots of research on epigenetics,
Starting point is 00:14:15 that what the mother does, what she eats, what she's exposed to, her thoughts, feelings, all those tag the baby's genes for what happens to them in the future, and whether they get diabetes, or heart disease, or cancer, or obesity. I mean, it's all programmed, but that doesn't mean it's not fixable. You can actually modify your gene expression. And that's what functional medicine is all about, is changing the environment, then the big picture of the environment, meaning your diet, lifestyle, toxins, et cetera, et cetera. How all of those inputs affect your gene expression is what
Starting point is 00:14:44 functional medicine is about. It's about modifying your lifestyle and your environment to influence your genes, to change your health in every aspect. Yeah. So for some people, it's harder for them than others. Like some people come in and they're like, it's just not fair. I have to be so much more careful than my friend Susie, right? And it's true, you know, because there are some people, yes because there are some people- Yes, there are some people that have to be so much more careful with their diet. I mean, we all should be eating a healthy diet,
Starting point is 00:15:11 but some people have to be more careful with the carbohydrates than others. Yeah, I would say, you know, there are a few people who are better adapted to higher carbohydrate diets and there are a a few i know a few of them and those are the ones who stay skinny eating anything but when you look at the fact that 88 percent of americans are metabolic and healthy almost nine out of ten of us have some degree of insulin resistance yeah you know that should get our attention it's it's it's probably the majority of
Starting point is 00:15:42 us who don't do well with a lot of starch and sugar yep and there's a continuum right some can do more some can do less some are look at a bagel and they gain weight literally because they're think about it and their insulin goes up and they put all the fat on their bodies i want to jump back to something you quickly talked about which is toxins and i want you to explain how environmental toxins and what toxins influence hormones and influence insulin resistance. Because both of those things are going on with PCOS. And I think it's something people don't understand.
Starting point is 00:16:14 Yeah. You know, this was impacting men more than women. But we realized it aged in orange, right? So when men were exposed, there may have been a few women. I don't really know how many women went to Vietnam, probably not very many, right? Not too many. Not too many. So when they were exposed to Agent Orange in Vietnam, they had a much higher rate, they have a much higher rate of getting diabetes with less weight gain, right? So that's when we
Starting point is 00:16:42 started to say, oh, this is interesting. There's a real interesting connection between toxins in the environment and our metabolism and our weight. And then we get diabetes. And they get diabetes. Agent Orange exposure had lots more diabetes. Lots more diabetes at less weight gain. So I'm just going to make this up here, make up some numbers, but just so people understand, they may have only had to gain 10 pounds or 20 pounds to get type two diabetes, where a typical American maybe was gaining 50 pounds before they got type two diabetes,
Starting point is 00:17:14 right, you know, just on it for an example. So they were getting type two diabetes at with less weight gain, meaning that there was more to it than just the weight gain, right? And that's when we realized that these toxins were damaging probably the mitochondria, right? So that powerhouse of your cells. We also know BPA, that plastic, that's been really well- Bistinol A. Yeah, really well studied to show there's a connection with insulin resistance. Yes. We've known for a long time
Starting point is 00:17:46 about the connection with breast cancer and BPA, but there's also this connection with insulin resistance and weight gain. So that hard plastic, they use BPA in the lining of cans or on receipts. Baby bottles. Baby, I know, right? Yeah, when you get your credit card receipt,
Starting point is 00:18:03 your gas station receipt, the people say join your system like no thanks okay because i i don't want to constantly expose myself gets absorbed through the skin yeah yeah so you know we realized that this toxin caused weight gain insulin resistance and and i'm sure there's a lot of other toxins that we haven't even you know figured out yet that are really influencing. Well, pretty much all the petrochemical toxins, all the plastics and all the fossil fuel derived
Starting point is 00:18:33 toxins are endocrine disruptors. And I read way back when we were at Canyon Ranch, I read a book called Our Stolen Future by Theo Colburn, which was about the ways in which these environmental toxins were disrupting reproductive health of animals and humans. And I was like, oh my God. And so what's going on is that these are not just one exposure. So you're not just exposed to BPA. You're exposed to literally hundreds of these in our daily life through our modern living.
Starting point is 00:18:59 And there are ways to reduce it. And I think the Environmental Working Group is a great resource for finding out what household products, skincare products, cleaning products, you know, are food products that you can eat that are not gonna be full of these chemicals. And you just go to ewg.org. So that's important.
Starting point is 00:19:16 So let's talk now about the gut because most people don't really think that your hormones are connected to your gut microbiome, but it's incredibly connected. Fascinating. It's so fascinating, but they've been, they've shown that there's certain types of molecules from the gram negative bacteria in our gut. So if the microbiome, if all of those trillions of bacteria are out of balance. And there's an overgrowth of some unhealthy bacteria in our gut that they have, these gram-negative bacteria have something on them called LPS or lipopolysaccharides, that these things can then, these components can get into
Starting point is 00:19:57 the body. And they've shown that this can trigger this insulin resistance in our body so that people, when they have higher levels of these abnormal bacteria, will have more insulin resistance. That's absolutely right. So there's a name for this. We call it metabolic endotoxemia, which is a fancy way of saying that the poison crap in your gut leaks into your bloodstream and your immune system goes, ah, and starts creating an inflammatory response, which then affects your insulin sensitivity.
Starting point is 00:20:29 So anything that causes inflammation, right? Anything, stress, bad food, toxins, infections, microbiome nastiness, all that can drive inflammation that can cause insulin resistance yes so you don't even be eating sugar right but if your gut's a mess for various reasons then you have to fix the gut and also um there's a lot of effect on on insulin resistance but there's also other effects in the gut around the kind of bacteria that are there and how they affect your metabolic processing of estrogens and other hormones.
Starting point is 00:21:05 So it's really important to eat the right kinds of fiber and the right kinds of foods and to feed your microbiome and your inner garden. So we've talked about a lot of things. We've talked about diet, we've talked about stress, we've talked about environmental toxins, we've talked about the gut microbiome. All these things play a role.
Starting point is 00:21:21 And so the job of a functional medicine doctor is to dig down and figure these things out. So how do we begin to assess these? And I want you to share a little bit about some cases, but how do we assess? Because it seems like a lot of stuff that you go to the endocrinologist or the gynecologist, they're not like looking at your poop.
Starting point is 00:21:37 They're not measuring your toxin levels. They're not looking necessarily at insulin resistance very well. What do we look at that's so different here at the Altria Wellness Center and through the lens of functional medicine? I mean, I think that's what's critical about functional medicine. And what we do is we get a really good detailed history. And that gives us a lot of information. So when we take the time to get to know our patient and get all of the history of their life, their timeline of their life, what things have happened
Starting point is 00:22:06 to them, what illnesses they've had, what disruptions they've had, what exposures they've had, what other things are going on in their body. That really impacts where we go and what we choose to look for. So you get a really good history first and foremost, and then that informs you what you want to test. You could test everything, but this ends up being a lot of tests. So what's important is to get a really good history so you know where to really focus. So for one person, it may be, I really got to look at their gut microbiome. I've got to figure, they've got this sort of history. I think that might be an area that we really have to focus on. I want to look at what
Starting point is 00:22:45 those, the balance of the good and bad bacteria are. I want to see if they have maybe some of these lipopolysaccharide components that may be triggering inflammation and insulin resistance. Or maybe somebody else, you know, you've got a sense based on their history and some of their other symptoms that it's more toxin related. Or somebody else, it may be more lifestyle related. And you've got to just really focus more on breaking that cycle of craving those carbohydrates. Because what happens for a lot of people is it becomes a vicious cycle, right?
Starting point is 00:23:21 They eat the carbohydrates, the real refined processed carbohydrates, their insulin goes up, but then they they end up they gain some weight then they crave more and more of them and it becomes this vicious cycle that gets out of hand and i think that's that's important yeah it's so important and we we really you know don't just look at the hormone levels which typical endocrinologists or gymo we look at those too but because they're very helpful and informative to look at the testosterone levels dht and look at DHEAS and all kinds of things that we look at. But we also do looking at toxin load or looking at the microbiome or looking at nutrient levels
Starting point is 00:23:53 or looking at insulin resistance in ways that may not be looked at. So tell us about the first patient you had who was 20 and she had these really irregular periods and acne and bad digestive issues. How did that all get started for her? Right. So she was 20 when she came to see me and she was frustrated with her acne. She was frustrated with her digestion. And her periods were kind of all over the place. She had a lot of ear infections as a child. So she was put on antibiotics and then ended up getting a lot of recurrent ear infections and more antibiotics and more antibiotics. And so I think that really just
Starting point is 00:24:33 set the stage for her microbiome to be out of balance. And then when she started having her period when she was 14, it never was regular. So from day one, she had an irregular cycle. So always, you know, one month it'd be six weeks and then two or three weeks and then she'd skip a month and then, you know, she'd be eight weeks between periods. So always irregular. And then as, you know, I'm not really that surprised just having done this for so long, but she also then in puberty developed a lot of acne. So, you know, probably because of some of the shifts in the microbiome in her young, young years, and then just all of these things going on-
Starting point is 00:25:12 And you see that a lot. You see kids, a lot of ear infections, maybe she's eating dairy, which commonly can cause a lot of congestion. They throw the antibiotics at the kids and then they get a little older, then they start getting gut issues and they start getting acne and other things. So it's all connected. Yeah. So what we did is, you know, because of her digestive issues and her acne and her irregular periods, I said, you know, I'm really curious about her digestive system. I really wonder what's going on in there. And, you know, could this be the driver of her insulin resistance?
Starting point is 00:25:45 And so we did a test that looks at antibodies against different components in the digestive system. And one of the things it looks at are these lipopolysaccharides, which are on these gram negative bacteria, which as we talked about, has been shown to trigger- These are bacterial toxins, essentially. The insulin resistance. And when we did that test on her, she had really high levels, which means that her levels were high enough to get into the body to trigger these antibody levels to occur.
Starting point is 00:26:20 So we also did a stool test. In the stool test, it showed that she had an imbalance. She didn't have enough of the good bacteria. She had an overgrowth of some unwanted bacteria. So she had this dysbiosis. And so I said, you know what, this is where we've got to start. This is where we got to focus to help both your skin, well, actually all your skin, your digestive system and your cycles, your periods. We did see when we did hormone testing that she had signs of PCOS. She had some high level of DHEA and her testosterone was a little bit high.
Starting point is 00:26:57 And her LH, FSH ratio was off. So we did see some signs on hormone testing that she had some PCOS going on. So Liz, when you treated her, you also took her off dairy. Yes. And I want you to talk a little bit about why dairy is bad, both for hormones and insulin resistance and acne, because she had all these problems. Yeah. So, you know, as you can imagine, dairy products, both milk and cheese and dairy products coming from a cow are full of hormones. You know, that cow to make cow's milk has a lot of hormones floating around. Those hormones get into the milk, even if it's
Starting point is 00:27:46 organic. Yeah. Yeah. And so. And there's more in ones that aren't organic. Yes. There's like 60 different hormones in milk. Yeah. And so, and some people are very sensitive to those hormones and they will cause acne production. They will, they will cause more acne, more... And then of course, a lot of people are sensitive to dairy. So it can cause a lot of digestive unrest and digestive issues. And what's also interesting to me is that when you look at people who consume dairy, dairy will spike insulin pretty high. A 300% increase in insulin consuming dairy, which I was sort of surprised at when I looked at the literature. Especially the lower fat dairy, right?
Starting point is 00:28:27 Because that, you know, and so for so long, we were going to the lower fat and then we were going maybe to the lower fat chocolate milk in school, right? You know, all those things that were spiking insulin. And I would say for women with hormonal issues, I think dairy's got to go for most of them to start at least to see how it affects them. Because- Absolutely. You know, whether it's irregular cycles or whether it's PCOS or whether it's acne, whatever is going on, I think it's an incredibly hormonally disruptive food for so many people.
Starting point is 00:28:56 And a lot of people can tolerate it fine. But if you've got problems, you've got to start thinking about what you've got to cut out. And I think what is really helpful a lot of times at the beginning when you're dealing with when you have a lot of things going on and you're not sure how food's impacting you, sometimes to do a full elimination of a food or a group of foods is really helpful because it gives you a lot of feedback. So sometimes if you just sort of cut down, you don't really go, I'm not really eating much dairy.
Starting point is 00:29:22 And I get that all the time. I don't really... I just have cheese after dinner. go, I'm not really eating much dairy. And I get that all the time. I just have cheese after dinner. No, I agree. It's like, it's hard for people to understand that, you know, a little bit can do a lot of damage. And the way I explain it to people is, think about like a peanut allergy. Sometimes if you're like just exposed to peanut dust, you can get an anaphylactic reaction,
Starting point is 00:29:43 right? That's how powerful your immune system, it responds to microscopic doses, right? So I think that's important to remember. So what happened with this young woman? You treated her? Yeah. So because we found this dysbiosis or imbalance in good and bad bacteria, we needed to get rid of the dysbiosis. So we used an herbal combination to treat that. We also gave her a lot of good probiotics and prebiotics, the things that feed the good probiotics. And we took her off of dairy. We also, we also, we did more of a comprehensive elimination diet at the beginning. So we took
Starting point is 00:30:17 her off of dairy, but we also removed gluten and a lot of other inflammatory foods and really focused on a phytonutrient rich diet. And I think sometimes we don't think about how powerful that can be, right? Those phytonutrients, those components from our plant foods that have amazing qualities in our health from lowering inflammation to helping detoxification to helping the process of elimination of our hormones that we want to eliminate. So they really are powerful. And so when you help people get those eight to 12 servings
Starting point is 00:30:50 of phytonutrients, which come from your vegetables, some fruits, some- Nuts and seeds. Yes, spices, teas, really that can be really powerful for the body. Yeah, so it's not just about what you eliminate, it's what you add. That's very true. teas, really that can be really powerful for the body. Yeah. So it's not just about what you eliminate, it's what you add. That's very true.
Starting point is 00:31:12 Yeah. I like to, I want to change the name called the addition diet. Yeah. I like that. So, so that was very powerful for her. We also added in some inositol, a combination product that has some myo-inositol and d-chiro-inositol, a combination product that has some myoinositol and d-chiroinositol, which actually helps improve insulin sensitivity. So we did this for a while as well. It can help improve the cell signaling in the body and improve how the insulin works. We also really repleted some deficiencies she had. She was low in D, vitamin D, which we know is important for insulin sensitivity. And she was low in vitamin A, which is important for skin. She was low in omega-3 fats, which is really anti-inflammatory. So we replaced a lot of the deficiencies that we found as well. That's amazing. And then what happened?
Starting point is 00:32:01 You know, what was great because her digestion improved. That was the first thing that got better. And then her skin, it got better. And then after a few months, her periods just started to really get regular for her. Yeah. I mean, it's just so, I get, honestly, Liz, I get so angry because I've been doing functional medicine for so many years. People suffer so needlessly from problems that do have solutions. And it's not rocket science. It's not like we need to know some great new discovery in medicine. We understand biology enough now using the lens of functional medicine and systems biology, which is now gaining more traction and people are becoming more aware of it.
Starting point is 00:32:38 But it's just so disheartening to me that it takes so long for people to get access. And I think I want to just sort of end with a case, a short case study that you had of a woman who had infertility. Because this is a problem that affects one in seven women. We've covered it before on the podcast, but I think I want to dig into this particular cause because it is one of the most common causes and also easily remedied. And I can't tell you how many women that I've treated personally, I know sure you have, who have this problem and you fix it and then they get pregnant. Yes, we see it all the time. It's phenomenal. So this woman was 34 and she came to see me because
Starting point is 00:33:14 she was trying to get pregnant and she had been trying for three, four, four plus years, I think, and had not gotten pregnant yet. And her periods were really irregular. And she was 34, so she was getting closer to that age where she was getting really concerned about the fact that she hadn't gotten pregnant yet. And she also noted that over the last few years, she had gained some weight. She was about 20 pounds overweight. Most of that weight gain was around her belly, which was making her frustrated, you know, and she didn't really feel like she was doing much different anymore. She also had to get some laser therapy done. So to remove the hair on her chin and on her belly. So she had had some laser therapy done and she was also struggling with acne.
Starting point is 00:34:05 She was on birth control pills from the age of 17 to 29 to really regulate her period. But when- I hate that. I hate that. When I hear that sentence, oh, my doctor put me on the pill to regulate my period. I'm like, well, why is it irregular? And let's figure that out instead of just slapping you on the birth control pill, which is not side effect free. Right. No, it's not.
Starting point is 00:34:28 No. And so, but when she went off of the birth control pills, her periods were irregular since then. And she developed a bunch of acne. So, you know, she really came in to really for us to help her with her fertility. And so we did testing and we found that her testosterone level was high. Her DHEA was high. Her LHFSH ratio was off, and her insulin, her fasting insulin was really high. okay, that this was an area that, you know, she's got insulin resistance, she's got PCOS, and that's really what's driving all of these things that she's
Starting point is 00:35:10 dealing with. And so when I got her diet history, which she filled out when she came to see me, you know, she said, you know, she was trying to eat healthy. She was having oatmeal for breakfast. You know, she was having that refined oatmeal that so many people are eating, thinking it's healthy, right? Sandwich for lunch. And at dinner, she'd have some pasta with some chicken or vegetables on it.
Starting point is 00:35:33 And so that's really where we focused. We really worked to lower that carbohydrate intake for her. We pulled away those extra refined and processed carbs. Oatmeal, you think it's healthy, she's having it at breakfast, but it was also healthy for someone like that. No, and especially a lot of the oatmeals out there, you know, and the way that we eat them. Like if we're eating a bowl of oatmeal with not a lot of other stuff in it,
Starting point is 00:35:55 there's none of the, you know, good healthy fats and protein to balance that blood sugar, right? So, you know, you can have some, you can have some steel, a small amount of steel cut oats with a lot of, you know you can have some you can have some steel a small amount of steel cut oats with a lot of you know nuts and um maybe some coconut milk and um and and and that can you you know for some people that can be a healthy breakfast but for her that's not how she was eating her oatmeal
Starting point is 00:36:18 and it was it was spiking her blood sugar and it wasn't helping with her with her weight it wasn't feel making her feel satiated and satisfied and it was yeah so so what did you do so we really you know food first with her we we put her on the pegan diet right you know we pulled away the um the extra refined carbs we said we when you're getting your carbohydrates we want them to come from vegetables you know that's where you're going to be getting most of your carbohydrates from, from the greens and the broccoli is a carbohydrate. Yeah, exactly. It's a wonderful, healthy carbohydrate, you know, and, and really rich in all those phytonutrients. We work to balance her blood sugar. So she had a good protein source and fat source at every meal.
Starting point is 00:37:00 And, and we got her exercising, you know, she had really kind of just, she was really focusing more on the fertility and working and had kind of like, let that go. So we got her on a good exercise program, both that included some, some high intensity interval training, and some good cardiovascular exercise and strength training. She was, she was a healthy woman. So we just had to get her moving again, more intensely. And, and within, you know, within a healthy woman, so we just had to get her moving again more intensely. And within a few months, three months or so, she lost that extra 20 pounds. Her periods regulated, and she got pregnant. That's unbelievable.
Starting point is 00:37:39 So basically, these are people who go to fertility doctors, spend tens of thousands of dollars. And what you're saying is all you do is take a good history and get all the starch and crap out of her diet and sugar, got her moving a little bit. She lost 20 pounds, her cycles regulated, and she got pregnant. I wish it was this easy for most people. Some people it's a little more complicated, but you'd be surprised at how many people just following this simple approach can make a huge difference. There was a book by one of the top Harvard scientists of all time, Dr. Walter Willett, called The Fertility Diet, that really focuses in on this whole idea
Starting point is 00:38:09 of why we have so much infertility and why it's such a problem. So this is an area where I get nuts because from a functional medicine perspective, it's relatively straightforward to sort through this using a very detailed history, the right kinds of diagnostic tests that you wouldn't get at your regular doctor, using a food-first lifestyle approach, fixing the basic things you need to get fixed, whether it's diet, toxins, you know,
Starting point is 00:38:35 allergens, low-grade gut issues that all can drive problems. And we just see amazing results. And it's so satisfying. And, you know and I think your work is just so incredible, Liz, and I'm just so happy we're all here at the Ultra Wellness Center because we get to see miracles every day, and they're really not miracles. They're just application of good science, but they seem like miracles, and I'm just so happy to be able to do this and provide this in the world, and I just want to thank you for your amazing work teaching functional medicine all around the world, virtually now, of course, but you really have been a leader in the field. And we have, you know, probably over 60 years of collective experience here at the Ultra Wellness Center
Starting point is 00:39:12 in functional medicine. So if you're suffering from any of these issues, we'd love to see you here at the Ultra Wellness Center in Lenox. We can do all virtual visits now. People can't make it here in person. And we'd love to see you. So if you love this podcast, please share with your friends and family. Share on social media. Leave a comment. And maybe you struggle with fertility or PCOS. And how have you solved your problems? And what have you found?
Starting point is 00:39:34 And subscribe wherever you get your podcasts. And we'll see you next time on The Doctor's Pharmacy. Thank you, Mark. Hey, everybody. It's Dr. Hyman. Thanks for tuning into The Doctor's Pharmacy. I hope you're loving this podcast. It's one of my favorite things to do and introducing you all the experts that I know and I love and that I've learned so much from. And I want to tell you about something else I'm doing, which is called Mark's Picks. It's my weekly newsletter. And in it, I share my favorite stuff from foods to supplements, to gadgets, to tools,
Starting point is 00:40:07 to enhance your health. It's all the cool stuff that I use and that my team uses to optimize and enhance our health. And I'd love you to sign up for the weekly newsletter. I'll only send it to you once a week on Fridays, nothing else, I promise. And all you do is go to drhyman.com forward slash PICS to sign up. That's drhyman.com forward slash PICS, P-I-C-K-S, and sign up for the newsletter and I'll share with you my favorite stuff that I use to enhance my health and get healthier and better and live younger longer. Hi, everyone. I hope you enjoyed this week's episode.
Starting point is 00:40:41 Just a reminder that this podcast is for educational purposes only. This podcast is not a substitute for professional care by a doctor or other qualified medical professional. This podcast is provided on the understanding that it does not constitute medical or other professional advice or services. If you're looking for help in your journey, seek out a qualified medical practitioner. If you're looking for a functional medicine practitioner, you can visit ifm.org and search their find a practitioner database. It's important that you have someone in your corner who's trained, who's a licensed healthcare practitioner, and can help you make changes, especially when it comes to your health.

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