The Dr. Hyman Show - How to Choose the Right Supplements (and Avoid the Wrong Ones)
Episode Date: May 14, 2025With so many supplements on the market, how do you know what’s actually worth taking—and what’s just a waste of money? In this episode of The Dr. Hyman Show, I sit down with Steve Martocci, a t...ech entrepreneur who’s applying smart tools and real data to help people finally make sense of their supplements. We talk about why most people still aren’t getting the nutrients they need—even if they’re taking vitamins—and how Steve’s new platform, SuppCo, is making it easier to figure out what to take, what to skip, and what to trust. You’ll learn: • Why 70% of people are still low in at least one important nutrient (and how that affects your energy, mood, sleep, and more) • The truth about getting everything you need from food (and why that’s harder than it sounds) • How to spot low-quality supplements and avoid harmful fillers and contaminants • Why your doctor may not know how supplements interact with your medications • How to SuppCo’s app can help you track all your supplements, avoid taking too much of certain nutrients, and personalize your health routine (BTW, when you download the SuppCo app, you can view my personal supplement Stack and Protocols). If you take supplements—or are thinking about it—this episode will help you do it smarter, safer, and more effectively. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive +++ SPONSOR COPY This episode is brought to you by Big Bold Health, Timeline, AirDoctor, and Sunlighten. Try HTB Immune Energy Chews for yourself, visit bigboldhealth.com and use code DRMARK 25 at checkout to get 25% off your purchase today. Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today. Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman. Visit sunlighten.com and save up to $1400 on your purchase with code HYMAN.
Transcript
Discussion (0)
Coming up on this episode of the Dr. Hyman show.
Why do you take a blue pill or a red pill or have titanium dioxide or have dyes and chemicals?
Yeah, these things that are not good.
They don't need to be in your supplements.
Steve Martosi is a serial entrepreneur and tech innovator.
Who turned his own health journey into a mission.
To revolutionize the supplement industry.
I wanted to live, but I was deeply unhealthy.
I got up to 300 pounds in college.
I found a functional medicine doctor.
We started doing lab work, right?
And we started experimenting and it worked. At that point, I probably lost 70 pounds. I got up to 300 pounds in college. I found a functional medicine doctor. We started doing lab work, right?
And we started experimenting and it worked.
At that point, I probably lost 70 pounds.
I was trained that vitamins make expensive urine,
don't waste your money.
If that logic was true, you shouldn't drink water
because you pee out.
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Welcome to Dr. Hyman's show.
I'm Dr. Mark Hyman.
This is a place for conversations that matter.
And today, if you are someone who's taking supplements, who's confused about supplements,
who thinks they create expensive urine or that they're essential are completely boggled by all the brands out there, all
the claims out there, all the people pushing it, you know, what to do for
yourself and how to stay healthy without harming yourself.
You're going to love this show because we have Steve Martosi who's co-founded
an incredible company called Supco.
And he is a brilliant guy.
I mean, he's a good friend of mine.
We've traveled the world together,
but I was sort of blown away when he took his intelligence
that helped launch GroupMe and Splice and Blade,
a lot of different companies.
And he's taken all of his business know-how,
his personal health story,
and has created something that
is missing in the marketplace, which is a trusted source of navigating what quality
is in supplements, what you need, and how to figure out what to do.
Because it's a mess out there, and I think you're going to love this conversation.
And we dive into why Supco is such a needed service in the marketplace to help you navigate
this incredibly messy landscape of supplements and quality and cost and all
the things we want to care about.
So I think you're gonna love this conversation.
Let's jump right in.
Well, Steve, it's so great to have you on the podcast.
You know, we've been friends for a while, traveled the world together,
done a lot of cool stuff.
We're both involved in two companies that I think are going to change
the landscape of health in America.
One is Function Health where I'm the co-founder and chief medical officer.
Another is SUPCO, which is something we're going to talk about today.
And it's something that's been desperately needed for decades.
Navigate the myriad of supplements out there on the market to find the quality that you
want, to know that you're not getting crap in it, to know that it's made in a way that actually meets
pharmaceutical grade standards,
to actually figure out what to do,
because it's a landscape out there that is fraught
with all sorts of problems that I've tried to solve,
but you've done a way better job.
See, you've kind of started and exited
many amazing companies like GroupMe and Blade and
Splice.
And I think there's this interesting personal story that you have about how you have sort
of understood your own health challenges and used your own way of navigating it.
And this is really coming out of your own struggles to figure shit out.
And now, you know, we have the opportunity to share this innovation
around how to think about supplementation
and whether you need them, why you should take them,
what the landscape is out there,
what the problems are with it, and how to solve that.
So you're sort of a multiple serial entrepreneur
and you've tackled this problem in a way
that I'm just so glad because for me as a practicing doctor,
it's so hard for my patients to actually figure out
what to take and that's why I spent decades
researching the market, visiting supplement manufacturers,
factories, going in there, doing quality control,
looking for third party testing,
making sure their ingredients were pure,
that they had no contaminants or chemicals or additives,
which often they do,
making sure that they're bioavailable,
that their forms of nutrients that work right,
and also that they're digestible.
When you eat them, they don't just poop out.
And that they're actually tested after
for both potency and purity.
So whatever it says on the label is what's on the label.
And I spent decades doing this,
and I've curated a small group of these supplements that I think work clinically
for my patients.
And we're gonna sort of go into how you solve the problem
at a much bigger scale.
Because you know, there's, I don't know how many products
are on the market.
We have tracked, we're tracking about 200,000.
200,000 products.
So it's kind of, I, you know, it's kind of insane
to think about how much is out there
and how much noise is out there and where's the signal
and what's good and what's bad.
So let's just sort of start by diving into your story
because you were a very overweight, unhealthy guy
when you were in your 20s.
I mean, 20s, I think my journey probably goes back
to my childhood.
I was always the fat kid.
I was a tall fat kid.
And I would make all the sports teams
because they'd be like, oh, he's six, five.
Like he's gonna, we can make him good, right?
He's gonna get better as time goes on.
But honestly, I had like nothing I would do
playing football.
You know, you do two a day practices and all nonstop
and I wouldn't lose weight.
And it was pretty wild.
My mom has hypothyroidism.
She took me to an endocrinologist.
This is like 1996, seven, something like that. And they did some labs and they just told me
I was on the low end of normal and they couldn't do anything.
Yeah.
And it was completely disheartening.
I thought that medicine like completely let me down.
And things got worse.
Like I got up to 300 pounds in college.
299.
I never saw 300 on a scale.
I refused to get on a scale once I was 299.
Like it just was not, it was not good.
And then, you know, I'm a software engineer. I just love refused to get on a scale once I was 299, like it just was not, it was not good.
And then, you know, I'm a software engineer,
I just love building, code is kind of my canvas,
it's just where I can lose days building
and it's so much fun for me.
Built a successful company called GroupMe,
it was a kind of pioneering group text messaging.
And when we sold that, we sold it quickly to Skype,
you know, I was 270 pounds, I had just made some money,
I wanted to live, but I was 270 pounds. I had just made some money. I wanted to live, but I was deeply unhealthy.
And I found a functional medicine doctor.
And this is 2010, so kind of ahead of the curve a bit.
So I've been doing this since 96, so that was like.
I had a social media curve at least.
I was 14 years later.
Yeah, yeah, yeah, fair.
Ahead of the curve of the biohacker trend
that I feel like is now.
We started doing lab work, right?
And we started experimenting, and started with some thyroid of the curve of the biohacker trend that I feel like is now. We started doing lab work, right? And we started experimenting,
and started with some thyroid medicine,
kind of dialed in some hormones,
and built a supplement stack, and it worked.
And I committed to diet and exercise again,
with these helping me this time, and it worked.
And people would ask me, they'd see my transformation,
and they'd ask what was I doing,
and no one wanted to hear diet and exercise.
And you lost almost 100 pounds. Yeah, I mean, at that point, I probably lost 70 pounds at that point. They're asking me what was I doing, and no one wanted to hear Diet and Exercise. And you lost almost 100 pounds.
Yeah, I mean at that point I probably lost 70 pounds.
You know, they're asking me what I'm doing,
and this is 10 years before I was Empic as a thing.
Yeah, yeah, pre-Empic.
This is not the easy answer.
So I would share them my stack,
which was the list of supplements and medications
I was taking, and it would be a ugly,
out of date Google spreadsheet.
Honestly, people didn't really know what to do with it,
but a couple people would be like,
cool, I talked to my doctor about this one thing.
And you know, then I went on with my life happy.
I started Blade and Splice and ran Splice for 10 years.
I was a little burned out, leading through COVID
and you know, getting ready to have a kid
and kind of wanted to step back and hire a CEO there.
You know, it was time to build again.
The software itch is just always in me
and I wanted to do something in health.
I mean, it had been a transformative experience for me
and it had become the zeitgeist.
You know, like your book was just coming out on longevity
and Peter Atiya's book.
It just seemed like the dinner table conversation
and the stack sharing on social media,
like it was happening.
Like this wasn't just a biohacker.
Yeah, I'm taking this, I'm taking that.
Yeah, it's like this was.
What are you taking?
Exactly.
And so that was the core concept
was to bring back the stack sharing concept.
You know, I saw what you guys were doing with Function
and I was so inspired by it.
I'm a Function investor, I'm happy about that.
But I wanted to tackle this space,
which I found to be an incredibly gray area
of understanding what to do.
And so that's where it formed.
I remember the first day I had the idea in my head,
some friend of mine came over for dinner
and without me saying anything,
she said, I spent four hours today
going through all my supplements,
putting them in a spreadsheet,
figuring out how to save money and take less pills.
Yeah.
It's like, oh, this is like a pretty good idea then.
And then like, I had another friend in the first week
say that their friend, they knew someone
whose mom had taken so much vitamin D,
they didn't know, she had dementia,
early dementia-like symptoms,
and she was like totally misdosing vitamin D.
And so I started to really like get into-
Because it wasn't what it said on the bottle,
or because she used too many pills?
I think it was too many pills.
We're not understanding the IU dosing
versus milligram dosing.
And that was the story I was getting.
And so we're really here to help you
make sense of supplements.
Let's talk about the landscape of nutrition
because I think most doctors, and certainly I was trained,
that vitamins make expensive urine. don't waste your money.
And your body gets everything it needs from food,
you'll be fine, and don't worry about it.
You know, there's a big fallacy in that.
First of all, if that logic was true,
you shouldn't drink water because you pee out
what you don't need.
Your body takes what you need.
So if you drink an excess amount of water,
your body will just get rid of it.
And that's the way it is for most vitamins, not the fat soluble vitamins. You have
to be careful. But it's crazy because you have 37 billion chemical reactions in your body every
second. And every single one of those chemical reactions requires a cofactor or helper.
And those are facilitated by enzymes. Enzymes need adverse nutrients to activate that pathway
so that one molecule can become another molecule,
which is how your body works.
And those cofactors are vitamins and minerals.
Literally, the grease lubricates the wheels
of your metabolism, and when I say metabolism,
I mean from a medical perspective,
which is every chemical reaction in your body.
And on top of that, you know,
there's other compounds that are phytochemicals
that are also, we're learning are so powerful
and we've consumed, you know, 800 species of plants
and foods with all sorts of phytonutrients.
There's, you know, probably maybe 100,000 phytochemicals
out there that have effects on the body.
You've heard of some of them like sulfloraphane from broccoli
or resveratrol from grapes or curcumin from turmeric.
And so basically we've been consuming these things.
Now we probably eat three main species of plants,
basically corn, wheat and soy.
And then maybe another total of 12,
you had tomatoes, lettuce, celery, carrots.
Like it's like 12 foods and you were missing
all these important phytochemicals
that also help regulate our biology
and that we've co-evolved with.
I call it symbiotic phyto adaptation.
So whether it's an actual vitamin you know that's essential
or an omega-3 fat or essential fatty acid,
or it's a conditionally essential nutrient,
there's many of those that you need more of,
depending on your state of health
or what's going on, like CoQ10 if you're on a statin.
And then there's all the phytochemicals.
And so there's supplements out there
that contain all these things.
It's kind of a morass of a landscape
that's poorly regulated, that is not well controlled.
I mean, the Deschete legislation in the 90s
helped sort of set the stage for a supplement industry
that you could kind of go wild
and not make disease curing claims, which was good,
but it kind of created a Wild West
where the whole supplement industry grew.
The question is, do Americans need supplements?
Do people in general need nutritional supplements?
Because if you listen to most doctors, you don't.
I mean, I think that is the thing that is so hard
as a consumer in this space,
is just the wildly different opinions.
And like it's the doctor gap of people who say
expensive urine to the ones who are like,
this is exactly what to do for this.
And it's also like the explosion on social media.
There's this whole kind of N equals one world right now
where people are raving about,
this supplement is just changing my life.
It makes me see in 4K.
But then they also have their supplement store
right behind it.
So it's an extremely difficult space to navigate.
I mean, there's a lot of snake oil sales.
There's a lot of snake oil sales.
Or, and look, there might be people who are having
actual real great experiences,
but they're not aggregating that data in a way that
allows anyone to make sense of it.
It's just their individual story.
And I think we're going through such a big battle right now
in America around the individual and the institution, right?
And like who to trust in this.
And that trust is really eroded.
Institutional trust is continuing to go down.
And 51% of Americans say that they have bought
a health or wellness product from a social media influencer.
From something they sell on social media.
Well I've bought shorts and shoes.
On supplements.
Yeah, fair, fair.
All right, see, well, can I dive a little bit deeper
for us into what is Subco and how it works
and why is it so important?
We like to say that we're helping users
make sense of supplements.
Through our website and app, we're helping you make sense of supplements. Through our website and app,
we're helping you figure out what supplements
are right for your health,
what products and brands you can trust,
how you can save the most money and get results.
To do this, we've cataloged over 200,000 supplement products
that you can search in our app
or by scanning the barcode.
And we've built an in-depth trust score rating
from 29 different attributes that let you understand
the manufacturing standards and quality of your supplements.
For those looking to figure out what they wanna take,
we have 80 expert protocols that you can go in
to find guidance on different health topics
like brain fog or heart health and women's hormones.
To get started, it's pretty easy.
You enter a little bit of information,
start scanning your supplements to kind of catalog
what you're already taking.
We give you an analysis of your stack
so that you can kind of get a score that's easy
to understand how you can improve quality,
how you can improve trust,
and make changes to kind of improve that.
You also then can share your stack with your doctor,
your friends, kind of get feedback from different people,
create a conversation around it.
That helps you understand if you're taking too much
or too little of something,
which happens to a lot of people.
And then we have a smart scheduler
that lets you make sure you're taking your products correctly.
Are you taking them with food?
Are you taking them at the right time?
Which will then also start tracking
to see whether or not you're getting results.
We launched a beta in early October.
The response has been amazing.
We're getting nearly 1,000 users a day right now. It's October. The response has been amazing. We're gaining like
nearly a thousand users a day right now. It's October 24. October 24. Yeah. And we're getting
a thousand users a day without even having your protocols. We're excited to get your protocols
and stack on the platform soon. And you know, I think what's for us people to know right now,
everything on sup goes free. And we'll launch a premium membership later this year, which will
have some premium features and eventually help people save money
on their supplements as well.
We don't sell any of your data.
There's no advertisement on Suffco either.
And yeah, we want people to come in and be aligned with them
so that we're just as excited when they stop taking something
that doesn't work as when they start taking supplements.
So you're not selling something.
We're not selling supplements.
And if we do, we will never profit from them.
We want to be- You're guiding people on how to-
You're guiding people on how to take the best products
for them that are the cleanest,
that are actually matching their goals and needs,
and you're just providing this incredible service,
which I think has such an important gap in the marketplace
that you're filling.
So what is the problem of nutritional deficiencies
today in America?
What do we know about the level of insufficiency
or deficiency of nutrients?
Is it widespread, is it rare?
I mean, look, I think this is your world.
I think this is the one that you particularly
would talk best about.
I know my own individual struggles,
but honestly, you've got this data.
This is your world.
I mean, the data's so impressive. When you look at the, and I'll just sort of share
a little bit to kind of set the stage,
but NHANES is called the National Health
and Nutrition Examination Survey,
and it's conducted by the government.
And every year they drive around,
they get blinded a whole bunch of people,
they test their levels, and they see what's going on
of all sorts of things, and nutrient levels.
And what they found is 90 plus percent of Americans
are efficient in one or more nutrient
at the minimum level to prevent deficiency.
And this is really an important concept for nutrients
because if you look at, for example, vitamin D,
you need maybe 30 units so you don't get rickets.
But you might need 3,000 units
so you don't get osteoporosis or cancer or dementia
or heart disease or dementia,
or heart disease, or autoimmune diseases, or a whole bunch of things that we call long-latency
deficiency diseases.
There's a guy named Robert Heaney who was a professor and brilliant scientist who wrote
a paper called Long Latency Deficiency Diseases.
What he was essentially talking about was like, yeah, there's nobody walking around really in America
with rickets anymore or scurvy or berry berry
or pellagra or xerophthalma.
These are these severe deficiency diseases
that we actually found in the turn of the century
when we started refining our diet
and taking white flour and white rice.
That's actually how they found it was in prisoners,
they gave them white rice, they all became deficient,
had these horrible diseases that were cured in a second,
essentially with minuscule amounts of nutrients.
When you look at the amount of deficiencies,
whether it's 90 plus percent deficient omega-3,
80 plus insufficient deficient vitamin D,
and some people say even more,
magnesium is about 45%, zinc's about 40%,
iron, you know,
we have a lot of efficiencies.
And with Function, you know,
we now have 150,000 members of Function Health.
And now, by the way, there's no waiting list,
so you can just join, go to functionhealth.com slash mark,
you can get in and go ahead and check your levels.
But we found that in looking at all the data,
almost 70% of our members
have a deficiency in a nutrient that is at the minimum reference range of the
lab. So in other words, for iron, this is an example, your ferritin level,
which is your iron source, should be 45 or more to feel good, to not have fatigue,
to not have hair loss, to not have insomnia.
There's a whole bunch of things that come with low iron.
The reference range goes 16 or lower,
but it should be 45.
Sure.
Right? Or homocysteine is just like the levels 14,
which should be more six to eight, right?
Which detects vitamin deficiencies.
Or vitamin D should be probably 45 to 60, not 30 or 20,
which some lab reference changes are.
And at the minimum level, which is how much you need
to not get rickets or scurvy or any of these diseases,
this is what the RDA is.
It's not the amount you should be taking,
it's the minimum amount you need to be taking
so you don't get some of these horrible diseases.
We're seeing almost 70% of people are deficient
in these nutrients in a cohort of 150,000 people,
which is a massive amount of data that we've collected at Function Health and
we're learning about the kinds of things we're seeing in the population.
So it's a real issue where people are not getting the nutrients they need and
they don't know why they feel bad. They don't know why they have these low grade
symptoms. I had one patient, she came in, she was a radiation oncology resident at Mayo,
and she had the most severe migraines.
She was on narcotics, she was on, you know,
major anti-vomiting medication,
and she could barely function.
And she came in and she said,
oh, I have terrible migraines,
and I started taking her history.
I said, oh, do you have other symptoms like constipation,
or do you have muscle spasms, or do you have anxiety,
or irritability, or palpitations, or constipation?
And she was like, yeah, I got all those things.
I'm like, well, that's a magnesium deficiency.
And it was so easy, and I gave her,
she needed like a thousand or more milligrams of magnesium
to get her going and to clear everything out.
And that cured her migraines.
And you hear someone who was at Mayo Clinic,
saw the best migraine doctors, did everything she could,
they couldn't even diagnose a deficiency.
And by the way, magnesium deficiency,
we test magnesium with function
and we get your red cell magnesium,
which is a better indicator.
But to do a real magnesium loading test
where you give people IV magnesium
and you see what they keep and what they dump out
is the best way to actually really tell.
But even so, just by history I could tell,
and after doing functional medicine for 30 years,
I can tell you without a doubt,
and doing nutrition testing on tens of thousands of people
and deep analysis of minerals and vitamins
and antioxidant levels and oxidative stress and CoQ10,
all the things that people normally don't look at,
it's so widespread, like nutrient deficiency
is so widespread in America.
So that kind of then leads into the question of,
well, if that's true, then why is that true?
By the way, what's shocking about that is
75% of Americans take a dietary supplement,
55% are regular users,
yet 70% are still getting those lab results.
So like they're definitely taking the wrong things
or not enough of the right things.
So I think that just speaks to a lot of the stuff
we're trying to sort out.
SUPCO is giving people the ability to actually know
what they're putting in their body.
One of the big features of being able to enter everything
that you're currently taking is you'll actually see
your nutrient totals across all the different products.
Vitamin D is coming from six of the products I take.
And actually having a conversation with your doctor about what's actually going in your body.
Doesn't really happen.
I remember talking to a nutritionist in the beginning,
and they're like, she was like very good.
She said, yeah, I've spent four hours, you know,
actually going over the nutrients that people were getting
from the products they told me.
But most people don't ever do that.
I don't know who has a conversation with their doctor
who knows actually what they're putting in their body.
I think this is really important.
So Sepco is your company that you started
to help solve this problem of what to take, quality,
how can you trust what you're taking,
what's the total amount of nutrients you're taking.
So people might be taking 10 different supplements
and like I said, they all might have selenium in them.
And then you're getting toxic doses of selenium.
And you don't know that,
because you're not adding it all up,
you're not putting a spreadsheet,
you're not doing the math,
and you created a product that does this.
Now I believe in this so much,
because it's what I tried to solve
when I started my own sort of store for my patients,
which was essentially trying to curate
a small group of products
that I personally had investigated,
that I visited the factories,
that I did the analysis,
that I looked at the third party testing.
My God.
I mean, I curated basically three, 400 products
for functional medicine applications,
for basically helping people with cardiometabolic issues,
for hormonal issues, for gut issues, and so on, so forth.
So that was a lot of work.
And I've been confident that I can recommend these things
to my patients or people who follow me,
but I don't think it really solves a bigger problem
of how do you figure out everything altogether?
And I know personally that I don't have enough time
to do this for myself even.
I'm buying different things, I'm using things.
They're like, how do I know?
So that's really why I become an advisor to SUPCO
and I'm sort of helping you
because I think this is such an important gap
in the marketplace and it's such a need.
When you look at the landscape today,
tell us some of the problems in the supplement industry.
Why is this needed?
Because people are just buying stuff
and they don't know where it's coming from,
where they get it.
They can buy it on Amazon and often this stuff
is sitting on a pallet for a long time
or it's like it's some sort of ripoff product
that doesn't have the nutrients in it.
So tell us sort of unpack the real issues
with the supplement industry as it is today.
As I said, we've got about 200,000 products.
There's like 195 already done,
and then a big queue of ones that have been submitted to us
that we're going through.
And that's up from 4,000 products in 1994.
That's all there was, right?
So it's been a-
4,000 to 200,000?
In 1994, there's 4,000 supplement products on the market,
and now there's over 200.
That's insane.
And so we've kind of gone in
and taken each one of the supplements,
taken the supplement facts labels,
and kind of taken the data so that you can get
an aggregate view of what you're actually putting in your body.
So that helps you understand what you're taking.
But in addition to that,
we've gone out and scored the top,
there's 8,000 brands,
which is insane too,
if you think about it.
We've taken the top 500, which covers a big percentage
of it and kind of expanding down the long tail now.
And we've given them a trust score.
And so we basically have gone in and done
what you were doing kind of manually
and doing all these individual reviews.
Built a 29 point system that goes in
and checks what certifications,
what kind of testing they're doing,
and kind of breaks it down and gives them a score.
That alone, that feature alone,
you can scan any supplement for its barcode.
And then you just take the bottle,
you put your phone on it.
Yeah, yeah, yeah, we can do it here while we're talking too.
Yeah, it's a pretty cool thing.
You don't have to manually enter it.
You just scan your code and it knows it.
You scan it, it pops up right away,
and you get the trust score
and all the information about the product.
It's super fast, it's super easy,
and the hit rate is really high.
And if we don't have something,
you immediately can submit it,
you can AI scan the label and it'll put it in the system.
And the queue is insane.
Like the long tail here,
there are 20,000 products in the system
that only one person is taking.
There's a long tail here that is absolutely insane.
And that's-
And those unique products that are kind of
not commonly taken.
Yeah, like one person's taking it.
I don't know how they found it.
I don't know if that's a trusted brand.
And you've seen an explosion on Amazon
of these kind of brands that are just quickly
coming to market because there's no real thing
stopping you from bringing a supplement to market.
You know, there's a big difference in the FDA
around the federal code between pharmaceuticals
and supplements.
Supplements are covered under federal code 21CFR111, right?
And that's basically that like, you know,
for pharmaceuticals, there's a whole process
that they have to get pre-approved following
CGMP standards and all these different things.
That's good manufacturing standards.
Yeah, current good manufacturing process.
You know, with supplements,
it's not something that gets done upfront.
You can be held to this standard retroactively,
like if something comes up,
but it's kind of up to you to just say,
you're doing this. It's self-pleasing.
You can get retroactively,
someone can say they're having a negative experience
reported with the FDA, they can say they're having a negative experience reported
with the FDA, they can come after you
for not following the practice,
but no one's checking upfront.
I mean, the amount of attention that the FDA pays this
is very, very little unless there's some
serious adverse effect.
Correct.
Or somebody has this problem with it.
Right, and those latent things you're talking about,
the like ones that might be heavy metal exposure
that take a long time to ever show up
or you don't know the source of it,
there's no guideline there.
I mean, a friend of mine was a researcher
and he actually analyzed Ayurvedic supplements
and found extremely high levels of heavy metals in them.
Totally.
So you're taking some Ayurvedic herb,
which is some natural product
and it hasn't been tested properly
and when they actually tested it,
it was full of heavy metals.
And even if you follow CGMP,
you're supposed to occasionally test your lots, I think it's like once a year. And then even then, they don't provide the guidance on heavy metals. And if you, even if you follow CGMP, you're supposed to occasionally test your lots,
I think it's like once a year.
And then even then they don't provide
the guidance on heavy metals.
It's like kind of up to you to be like,
well for this type of product, what should the,
Prop 65 helps a little bit, you know,
in terms of making sure you don't have to put the label
on there if you exceed those numbers.
But it's a pretty wild west to be perfectly honest.
And there are systems now that can say,
come up with an idea and a brand
and get a supplement and market in weeks.
So that's why you're seeing the explosion.
So we've gone in and we've taken 29 different points
and we've built a scoring system.
This is your trust score.
This is our trust score.
So basically you're taking 29 different attributes,
whether it's toxic.
Lot testing, CGMP.
The biggest one that makes a difference is whether or not you're getting a third party to certify your CGMP, if whether, the biggest one that makes a difference
is whether or not you're getting a third party
to certify your CGMP practices, right?
That's like kind of like the fundamental.
So instead of you just saying, yeah, I'm good,
I'm gonna self-certify that I'm following these practices,
there's NSF and UL, these two big firms that'll come in
and do what you are doing, go tour the facilities,
kind of do, make sure you're actually following,
give you a certification.
That's like a fundamental big one.
And there's a surprising number of brands
that don't follow it.
And that means that the manufacturing plan is clean.
Oh yeah.
The way they get the source ingredients.
They're testing each lot, you know, and like there's,
there's a lot, you know, to that, to figure it out.
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When I started in this field in functional medicine 30 years ago, there were a handful of professional brands
that were only marketed and sold through professionals,
doctors, nutritionists, and so forth, chiropractors,
and you couldn't get them otherwise.
You couldn't get like Medigenics or Thorne
or Pure Encapsulations, they only distributed
through professionals because they were higher level,
higher grade, a little more expensive,
but you get what you pay for.
So for example, Pure Encapsulations,
they actually test every single product, every lot,
and we do it before they make the stuff with the ingredients
and they do it after.
And if it says, you know,
I suppose they 400 milligrams of,
let's say magnesium on the label,
if it's 350, they throw it out.
Metagenics who you brought up is our 10 out of 10.
They're our highest scoring brand on the platform.
They do like one thing that is rare,
but we really, we give some points to it,
is they make every batch test COA publicly available.
So you can like look at your bottle,
look at the lot number, go online,
pull it up and see the results from the test.
That's like a gold standard for us.
Pure ranks very highly,
and there's, but then there's a big spectrum.
You know?
I mean, and the stuff that you get in the grocery store
or Walmart or the drug store is generally crap.
Like you sent me, they texted me a screenshot of Centrum.
Yeah, we just did not know about this.
Which is, you know, this massive advertising.
It's really a big product out there.
Everybody thinks Centrum is high quality.
It's good.
I mean, but why do you take a blue pill or a red pill
or have titanium dioxide or have dyes and chemicals?
That was a super interesting thing about that centrum pill
in particular is that the centrum brand ranking
is pretty high, but we just started exposing the excipients,
the inactive ingredients.
And it had titanium dioxide, red 40, red five,
like these things that, I'm sorry, yellow five,
these things that are not good.
I mean, titanium dioxide is not, it's banned in Europe.
You know, like it causes DNA damage
and they don't need to be in your supplements.
So that's another thing we just rolled out
was not just the manufacturing standards,
but now we're going down to the product level
and actually going in, we have like a,
forget how many, it's a couple thousand
of these excipients that get added,
and bringing them out by how cautious you should be about
the women in there.
Yeah, and there's a lot of stuff in them
that often are not known.
Like, there could be gluten or dairy,
like lactose or other things that are in these,
in addition to all the other kind of excipients,
fillers, additives, colors, chemicals,
things that make it look good or stick together.
And I mean, you don't want that crap.
You want the nutrients.
And I think it's gonna be interesting.
We're starting to send out different supplements
for our own independent testing to do what you were saying.
Just kind of verify that even if they're highly rated,
are they, is it actually in there what they say it is?
So the precision of the nutrients
that they're claiming are in there.
It's a complicated market.
And I think that what we've done though,
by just making a simple score, like making it out of 10 is like,
it makes it really easy for people to understand, right? The simple, like red,
yellow, green, like you can go deep and you can go look at each of the 29 points.
Your trust score is 1 to 10. Like this is a 9, this is a 2.
That has been helpful for people to just like simply take a glance.
Cause some, the user base we have, you know, one thing I like doing in general when designing
software is it's got to be easy enough for grandma to use, but powerful enough for, you
know, the most hardcore user in the space to go deep on.
Right?
I did that with Splice, making sure that 40% of top 40 music using it to create music,
they're like the hardcore guys and the brand new music creators.
Right?
So we're doing this in supplements, right?
There's a, there's a way to dive way deep into what those 29 points are
in each one of the excipients and all that,
or you can simply look at the score at the top
and be like, okay, that feels good.
Because some people just,
we gotta meet the consumers where they are.
Because nobody's really doing that.
There was a company called Consumer Labs
that I used to kind of use to reference stuff
where they would go and test products
and I would rely on their independent analysis.
But they weren't able to do the 200,000 products.
So you basically, just for the simple scan of barcode,
the technology behind it, the use of AI,
I mean it's quite amazing now.
You can literally see what is the problem
or how good a product is and whether or not it actually says what it is on the label.
Yeah, and I think the big thing too is we're not out here to,
we just wanna kinda arc the industry
in the right direction, right?
Like some of our trust scores, if we find a negative one,
we're not all doing the big gotcha story on it.
We're having conversations.
A lot of the brands have reached out to us.
First, the top end brands are like, thank you.
Right, thank you for simplifying and raising to the attention
how much work we are putting into testing this.
So like, super appreciative, you know,
sometimes they'll clarify a piece of data
that we might not have right,
cause we've collected it through our teams,
you know, reaching out to them
and they might provide something, which is great.
And then we've had brands also reaching out,
one, they want their trust work,
the consumers are starting to care about this.
And then how do we make it better?
Right?
And that's our big dream.
If we can just help the industry move in the right direction
on this, with the scores,
I think we've done something really great.
I think what you're saying is also important
because people are taking these things.
There's a, I don't know, $40, $50 billion industry.
Totally.
It's not well regulated.
And it, you know, nobody's sort of looking at quality or efficacy
or bioavailability or what form the nutrients are in.
I mean, there's so many levels.
If you take, for example, magnesium oxide,
a great example, I was in the hospital
for a back surgery recently,
and I was taking painkillers,
which can make you constipated so I wanted magnesium
and I said to the attending physician,
I said I wanna get this magnesium, he said sure.
And he wrote a prescription, what are you ordering?
He said well this is such a product.
I said that's magnesium oxide.
That's so poorly absorbed and it's also something
that doesn't work for constipation that well.
I said how about magnesium citrate?
He's like, oh, he looked it up.
He's like, oh, you're right.
I'm not kidding, you mark this as true story.
My fiance Kelly with her OB, her fetal mouse and doctor,
she was having Restless Leg Syndrome
and magnesium oxide was the only one the doctor recommended.
We were like, where are we?
And like, you know, like it just felt very out of date.
And he's like, best in his field and all that,
but for nutrition, we're not following his advice.
One, we don't, as doctors, we learn very little,
if anything, about nutrition.
Was it like 20 hours or less in a day?
Less, yeah.
And it's usually, for me, when I learned nutrition,
it was about all the deficiency diseases
that were happening in the developing world.
So it was interesting, like morasmus and Quashioracorin,
Xerophthalmia, which is a vitamin A deficiency,
has blindness and beriberi and pellagra.
So this is preventing the disease at the very low end.
I'm like, okay, great, I've never seen any of these diseases,
I probably never will.
I think I remember when I was a kid,
I did know people who had had rickets
and they had bald legs, so I had met them, but there were people,
the era before the vitamins were fortified
in milk and in food.
But these are things I didn't see,
and that was my nutrition.
My daughter is graduating now from medical school,
and I'm very proud of her.
She got into orthopedic residency
and got medicine, so I'm so proud of her about that.
But anyway, she's like, I ask her,
what are you learning about nutrition?
She's like, nothing really, like zero.
I mean, it's like amino acids, fatty acids,
sugar, whatever, like basic stuff that's not,
I think what do you have your patient eat for lunch?
And then supplements, almost nothing, right?
You don't really learn about them, what they do,
how they work, the assumption that the food is adequate,
we're getting it from our food, but our food's depleted.
I mean, we look at data back 40, 50 years, the quality of the soil, the organic matter is depleted
because of our farming practices,
the interaction between the microbes
and the organic matter and the plants
is actually how the minerals and nutrients are extracted
and from the soil and to get into the plant.
So we're seeing between five to 40% decrease
in a lot of key nutrients.
And on top of that, we're seeing people eating
more and more processed food,
and so not getting nutrients, and eating more and more.
Part of one of the things that happens
when you have a deficiency is you try to find
more nutrients somewhere.
Like animals do this.
I remember being in the Amazon,
there was this mineral deposit across the bank of the river,
and there were all these birds are flocking,
just eating the dirt.
You know, and I saw this also, yeah,
in the Amazon a couple of times,
and I was like, wow, this is fascinating.
You've got like thousands of birds of all species
coming to get the nutrients they need.
So animals know, and kids will eat dirt
if they're iron deficient,
because they want to get iron from the dirt.
Somehow the body knows,
but we're so eating such a shitty diet,
and it's so processed, and it's so devoid of nutrients,
although some of it's fortified,
it's only fortified because it's so impoverished
to begin with it, otherwise it wouldn't even be fortified,
and it's caused a lot of problems in the population
that we're seeing increasing nutrient deficiencies.
The problem is that people don't know how to diagnose it,
they don't know what their symptoms are related to it, they don't know how it makes them feel.
And so they think this is just how I'm supposed to feel.
You know, I feel like crap,
or I have this symptom or that symptom.
But often it's related to their diet
and their nutritional status.
And then there's the whole problem of like drugs,
and drug nutrient interactions.
And there's a whole host of those.
And so people are taking all these drugs,
like statins for example,
which is the number one prescribed drug.
You know, statins.
It interrupts the enzyme that makes cholesterol.
That same enzyme makes HMG-CoA reductase.
It makes CoQ10.
So you're blocking CoQ10.
What is CoQ10?
It's essential nutrient for making energy from food
and your mitochondrial function.
So people get muscle injury and muscle pain
and elevated what we call CPK,
which is damaged muscle enzymes because of this.
And doctors don't recommend, usually,
CoQ10 with statins.
Personal story on that.
So, you know, I got into this kind of longevity movement
young, 30, and I did a calcium score at age 30.
Which is like a heart scan.
Heart scan, see how much plaque I have.
Zero at age 30.
At age 35, I had eight, so that was something.
And I was off the charts.
And so I went on a statin at age 35.
It was not recommended to go on CoQ10 at the time.
No.
It ended up finding it myself, right?
Take my DoQ now.
You know, it's just one of those things that feels essential.
But it can be totally missed in the doctor's office.
And there's actually a book, a textbook,
medical textbook on drug nutrient interactions.
Because there's so many.
The next kind of one of the class of drugs,
I think it's the third after,
two or third of the most prescribed drugs on the planet
are acid blockers for reflux or heartburn. I think it's the third after, two or third of the most prescribed drugs on the planet are
acid blockers for reflux or heartburn,
which is because our diet's so crappy.
I mean, if I get stuck somewhere
and I have to eat something crappy,
because I'm starving, I'm at an airport or whatever,
and I try to do it, I will get immediate reflux or heartburn.
And I'm like, it's because of what I'm eating,
it's not because I have some defect
that caused me to have reflux.
And you take this drug for a long period of time,
it inhibits mineral absorption like zinc and calcium,
you get osteoporosis, it inhibits B12 absorption,
which is critical for so many functions,
it can cause depression, dementia, neurologic issues.
People don't know this, and we don't know
how these all are interacting,
and so we see another layer of problems
in terms of nutrient deficiencies
that's not being addressed.
Yeah, and that's one of the things I think together
as we keep navigating the space
and increasing the functionality on sub-code,
the interactions I think they're gonna be
really important to have on there, right?
And there's like the ones that you should be aware of,
like St. John's wort,
reducing effectiveness of birth control and antidepressants.
Vitamin K interacting with blood thinners.
Like there's a lot.
There's legit stuff. Yeah, and that's a layer that we want to get into
as we keep going.
We think that getting people's stacks on there now,
knowing what they're taking,
and then giving them the jumping off points
to improve things and find the warnings.
It's huge.
It's huge.
Like if you're on a diuretic,
which many people are for blood pressure,
it causes you to leach out minerals.
Like so you leach out magnesium and you pee them out.
And so we've seen these massive symptoms
of magnesium deficiency which are sort of,
doctors don't know how to diagnose and it's pretty easy
but there's this moment where I think we're,
what you're creating with Supco, this company,
there's gonna be a sort of a realization that one,
you know, with a partnership with Function,
which we're working together, which is testing.
So I say test, don't guess, you know?
We check your magnesium level,
we check your level of B vitamins,
like homocysteine and methamalonic acid,
which measure B12, folate, B6 effectiveness.
We measure omega-3s, we measure vitamin D,
we can measure zinc, we can measure zinc, we can measure copper,
we can measure iodine, we can measure
so many different nutrients, minerals,
that are commonly deficient in people.
And then people can actually then go figure out what to do.
Because we don't actually, with Function Health,
recommend any particular brands,
but we want some way to help people navigate
what's going on there in the landscape
and actually come up with a coherent strategy
of what to take and where to find the products
and how to trust them.
And that's kind of a future for us, right?
There's an evolution of where,
so we launched our beta in October.
It was kind of an early beta that to just,
I had to update my LinkedIn,
so I was working on something new,
so we launched in beta.
And it's going great.
But what exactly what you're talking about,
why we're working together,
why we have the function partnership is,
we really do want to incorporate more data.
And there's kind of a church and state mentality too,
around the product recommendations
and the nutrient supplement recommendations.
The product side feels like the things we were talking about,
the trust score that's based on manufacturing,
like quality, cost, and then some of the dietary preferences,
like, do you want vegan, you know, that kind of stuff.
But the nutrient recommendations,
you know, right now they're kind of generic.
We ask you basic questions, height and weight.
We have 80 protocols.
You can go in for different health goals
and kind of see the general recommendations there.
But we really need to up the game there, right?
And people want our number one most requested feature
is a personalized supplement plan.
And so that's what we're working on, right? It's a big thing to take in as much data as we can
and help people understand what they need to take. Once they understand that need, we the, the,
the how you get it in your body, you know, the, the cost, the which brands, all that, that can
become an independent thing that might even change over time, right? New products might come out,
lower cost options might come up higher trust scores may change, but we need to make sure you
have a really good nutrient plan and that eventually you're also going to need to track
whether or not you are hitting your goal. And so like one of the things we talk about a lot is
being aligned with the customer to be just as excited when they stop taking something that's
not working as we are when they try something new. And so, you know, it's a big part of our overall
kind of ethos is being your companion to navigate the space.
It's almost like Consumer Reports,
that magazine that tests products,
it sort of checks quality,
but it doesn't really exist for the supplement industry.
And it's not integrated into a flow, right?
Like there are some websites that you can go to
and look at some lab results and things like that,
but there's not like action to take, there's buy.
But like that's not really
the thing we're looking about.
We wanna make sure that you can have a conversation
with your doctor about what you're actually
putting in your body.
Look for alternatives, you know,
that might be cheaper cost than the thing
that you found through some influencer's website
and that you're tracking results.
Like alone, our scheduler, you know,
30 to 50% of supplements don't get finished,
the bottle that you buy.
People just stop.
They stop, they forget.
A lot of things, they forget is the one thing, right?
And then, I don't know, some people have just very much
the wrong expectations up front.
Like they think they're gonna feel something immediately.
They don't understand what the protocol is
to actually getting the results they want.
They don't know that they should be actually
checking their vitamin D levels in six months
or three months. And so.
You might notice the absence of something.
In other words, I talked to this woman the other day
who did her function test and she had a vitamin D level
of 20, which is extremely low.
And I said, gee, your vitamin D is low,
you could have more frequent infections,
you could have seasonal affective disorder,
you could have muscle pain and aching.
And she looked at me and she was like,
yeah, I have all those things.
So when you take something and you go,
well, I'm not noticing something, I'm noticing the absence of something. So when you take something and you go, I'm not noticing something,
I'm noticing the absence of something.
I'm not getting sick all the time.
I'm not having muscle.
I don't have muscle pains
while I'm taking high doses of statins.
So that's the thing.
We really wanna set people's expectations, right?
And also that they're dosing it,
they're taking it at the right time.
People don't follow,
it's very rare that people follow the with food,
without food.
Yeah, because you talk about that for a little bit in terms of different nutrients and how you need to take them with food without food. Yeah, because you talk about that for a little bit
in terms of different nutrients and how you need
to take them with or without food.
Yeah, I mean the fat soluble vitamins like AD, EK
should be taken with a meal to help improve absorption
and it can impact it by up to 50%.
With fatty foods.
Fatty foods particularly, let alone any food.
Right, so if you're taking your vitamin D
you have to have it with some fat.
Right.
As opposed to vitamin C which.
So we have a scheduler in the app too
that lets you, you know, takes all your different products
and then helps you build what time of day
you should be taking it at, set reminders for it,
and soon track whether or not you're experiencing
side effects or the results that you're looking for.
So we've got to kind of close that loop,
then feed that data back in,
help you optimize, make changes,
and kind of keep improving things,
and it'll be a journey.
And then you get feedback from people
about how they responded, so you get sort of data on.
That's gonna be the key, right?
To me, like right now we have the protocols,
and the products, you can see how many people
are taking them, but how many people
are actually hitting their results, right?
And I really struggle when I look at reviews,
like on Amazon reviews for supplements.
It's usually like one of three things.
This changed my life, this did nothing,
the package came damaged.
Like that's all that's happening on these Amazon reviews.
There's no one actually seeing
whether or not they're hitting results with it.
You know, we definitely aspire to do that.
We talk a lot about the creating that closed loop experience.
And I think that's when the N equals one data
starts to become really valuable.
So what does N equal one mean?
N equals one is like one of one, it is my data.
I am an individual in this.
It is not the clinical result.
It is not the aggregate.
It is just my personal, you know, data.
So you're testing your own biology against your own body.
It's just your own story, right?
It could be subjective, but it's the N equals one
is the sample size is me.
And that is the, you know, as we talk a little bit about the battle of the institution and the individuals,
you know, there's so many people on Twitter,
if you get caught up in your algorithm
on kind of the supplement health Twitter,
you just see people making some pretty outlandish claims
about the impact of supplements,
certain supplements on their life.
And we need to start feeding that back into a system
that can aggregate whether other people are having those experiences or just the loud voices on
on Twitter having those experiences on X because you know those people stand out and people make decisions as I said before like 51%
of people buying a health or wellness product because they saw it on social media. That's real. Even though the trust with them is not necessarily high, they are making these decisions. And so we can really find out whether or not
these are working, because some of these things
are in complete contrast to what the medical world thinks.
We need to build better data sets.
And you're also helping solve the problem of quality
in the sense that there's so many products in the market
that have stuff in them that should be in them,
whether it's performance enhancing,
kind of male enhancing drugs for sexual function, to have stuff in them that should be in them, whether it's performance enhancing,
kind of male enhancing drugs for sexual function,
might have Viagra in it, or you could have.
That came out recently.
That was FDA went after a brand
for having a bunch of these natural supplements,
having Viagra in them and all that.
And there was a scandal even in the kind of
Amazon basics world where they had tested
some of their products and they weren't
hitting the numbers that they said. There was a Ginkgo bil kind of Amazon basics world where they had tested some of their products and they weren't hitting the numbers that they said.
There was a Ginkgo biloba test that the FDA I think did
where there was zero of the product.
There was zero Ginkgo in the actual product.
So you buy a product that's a Ginkgo,
but there's like nothing in there.
There's nothing active in it.
And so you were kind of in a wild west out there
and you're trying to help people solve it
for many levels, like helping understand
what they're taking, whether the dosing is right
and you're taking too much or too little of something,
whether the quality is there, whether there's contaminants,
these are things that are so important.
And what's really interesting to me, Steve,
is when I talk to doctors,
you would kind of ask a group of doctors,
how many people recommend supplements to their patients
and very few hands go up.
Or though more, it's more and more now.
If you ask that same group,
how many of you are taking supplements?
Like 70 or 80% hands go up.
And when I got to Cleveland Clinic over 10 years ago,
we did a survey of the physicians there,
of 3,000 physicians.
And it was so fascinating
because we wanted to know whether they were interested in having a source
of trusted brands that were verified and certified
in sort of a similar way that you've done,
and what their uses, recommendations are.
So it's like, how many are you actually recommending?
It was very few.
How many would like to actually have a source
where you could trust, and it was like almost universal yes,
70% of the doctors were actually recommending stuff already.
And you would know the cardiologists
were recommending fish oil or COPU-10.
The gastroenterologists were recommending probiotics.
The OBGYNs were recommending prenatal vitamins.
And the endocrinologists were recommending vitamin D
for osteoporosis.
And so, but they didn't know what brand.
Totally didn't know what to take.
And, you know, for example, vitamin D is a great example, because when I learned medical
school, there was a prescription vitamin D, which is vitamin D2, which isn't really the
optimal vitamin to take.
You want to take vitamin D3 and doesn't work as well for many reasons.
And so, but that's what we learned in medical school, that this is what you do in your residency.
And so it was really interesting to see
the number of physicians at Cleveland Clinic,
which is one of the top institutions in the world,
who were taking them, recommending them,
wanted to have a quality source,
and there was just nothing.
And so I think, despite doctors being
a little bit negative on it,
it's partly because it's so unregulated.
It's partly because people don't know what they're getting.
It's probably because they don't have a sense
of quality control or how to actually recommend stuff
they know is gonna be safe and effective
and not problematic, unless it's a prescription vitamin.
And there are a lot of prescription vitamins.
A lot of prescription vitamins.
You know?
I mean, this is what I'm so excited about,
about us working together.
I remember when I showed you the platform initially
and it was like, whoa, I've wanted this for 30 years,
but like, I'm a tech guy, right?
Like I love to build, the initial version of this
is built out of the product that I really wish I had
and for stack sharing and creating all that.
And then my co-founder, Nick,
came up with the Trust Score Rating.
And the other thing we have is this Sub Score Rating,
which is take everything that's in your stack,
grade it against the brand qualities, price,
does it hit your demographics,
are you aligned with your health goals,
and kind of give people an easy score to iterate on, right?
So these are some of the core functionality we have,
but getting into the mind of the people
in the clinical world and what they need
and how to kind of interface with them,
where this really focused more
on the self-directed health journey.
But it seems like there's just so much with your guidance
that we're able to kind of tap into the mentality
of the doctors and how patients can kind of interact
and show them their actual supplement list right now.
Like you can actually share it with your doctor,
which you go to those intake forms and it's just like.
Oh my God, I don't.
I take supplements. How do you even fill them out? Yeah, I know, they get so mad at me when I try go to those intake forms and it's just like. Oh my God, I don't feel, I take supplements.
How do you even fill them out?
Yeah, I know, they get so mad at me
when I try to not fill them out, you know?
I mean, here's a spreadsheet.
Yeah, exactly, right?
And so now it can be a link to us
and you can actually analyze it
and we'll see what doctors really wanna take the time
to kind of take action on it, but we're gonna navigate.
It's a pretty exciting moment
with this sort of innovation in the industry
that's been a gap for so long.
It's been an area that's just been self-directed,
blindfolded, trying to find what's good,
hoping the company that you buy the product from
has got integrity, hoping that it's gonna work.
I think it's a lot of money people spend on this stuff.
How do you actually find the quality?
And I think the money side, though, is a big one, right?
So one of the things that we really wanna do over time
is drive down the cost of supplements.
There's a big problem in the industry
is that they're really not designed.
Like in my mind, when you think about taking a supplement,
especially some of these like core ones,
you should be thinking about your customer's lifetime value
in years or decades.
But so many, because of that, 30 to 50% of people
not finishing the supplement, not reordering,
the way the margin structures are
and how much they're costing to acquire customers
keeps the price really high for people
who are on stuff for a long time.
I remember I was on year five of taking Elysium
and I was like, guys, I sent customer support an email.
I was like, you've made all your money back on me.
I wanna take this for my whole life.
Can I get like a discounted rate on this? And they said no. And I was like, you've made all your money back on me. I wanna take this for my whole life. Can I get like a discounted rate on this?
And they said no.
And I was like, cool, I'm out.
Like, I'm just, you know, that was just-
Why do they say no?
Their customers, they said they don't have that yet.
And I was like, cool.
Like there's not a real reward for the people
who are in this for the long haul,
who are taking, there's not a system designed
for people who are in it for the long haul with their health.
I mean, we should be measuring their LTV in decades,
not months.
And lifetime value.
Lifetime value, yeah, of the customers.
So we're trying to find the right intersection
between capitalism and health
and help drive that down for people.
Like, you'll see that from us later.
And what's kind of cool about CEPCO also
is you can put in what you wanna be taking,
let's say function, health recommends not products, but ingredients or nutrients you need.
You could put that into the system,
and then it'll come up with a ranking
of which products are the optimal ones,
the best price, the best quality.
How do you take the rest of the amount of pills?
Like that'll be a big focus.
The least amount of pills.
So you solve so many problems with this.
I think one of the challenges
that the regulatory
environment has got to change.
So I don't know if it will or not.
I mean, I'm curious.
You're so, you've done so well on the policy front
and I think a lot of change for things that you've been
carrying out for a long time are starting to come
into taking action.
What do you think of the regulatory side of the space?
And I think the Desichet regulation was a necessary
set of regulations at the time,
because it was kind of the Wild West,
and there was nothing guiding what people could say,
because you could literally say,
you know, take this pill,
it'll make your penis grow six inches longer,
or it'll cure heart disease, or it'll,
and people were just, so it kind of came up with some
kind of limits on what you could market it as,
which I think was good,
because it can create structure function,
and that's why you say it supports healthy blood sugar,
supports a healthy immune system,
but you can't say it treats diabetes, right?
Even though it might help like bitter melon,
or certain compounds actually can help
with blood sugar regulation, right?
Or like berberine and so forth.
You can't say that it actually, but they do.
It works, berberine's a good one.
Yeah.
I think there's a lot of messiness
that got left over from that regulation,
which was in the 90s,
which helps sort of set a level of standards.
The FDA can't police at all,
and right now, your kind of,
SUPCO is kind of like the police,
sort of the FDA of supplements in my mind,
because you're basically doing a lot of the work
that they should be doing.
You've actually done the homework,
kind of look at all the products,
look at what's in them, kind of find the sources.
How do you actually find, when you look at a product,
whether there's contaminants or fillers or excipients
or things that shouldn't be there?
For us, it's about bringing the awareness
to what we have found, right?
So the manufacturing process,
do they have the COAs that show this?
Are they doing their lot testing?
So there's like, are they following the guidelines
that they should be?
And then the excipients list that we have in there
is helpful too, so that you can see
the inactive ingredients.
But then we're gonna try to do a bunch
of our own independent testing as well
to verify these things.
Personally, I like the edge of medicine
where we have a lot of agency over what we're doing.
We don't necessarily need prescriptions for things.
We can make our own decisions,
but there does need to be something
that's giving consumers guidance,
and that's kind of what we're trying to be.
So in the absence of new policy,
we're gonna keep trying to up the standards
and push the industry in the right direction.
It's so important, because as a practicing physician
who's been doing functional medicine,
using food as medicine, using nutrients, using herbs,
it's a challenge, because how do you actually
find the right product for your patient that's gonna work?
And it's sort of the, when I first started out,
I would call the sort of elders in the field,
I'd say, well, which probiotics should I recommend or which magnesium product or which this herbal product is good
I mean I did there was no way to know and I began to see what was working clinically
What wasn't working clinically and when you start to apply these clinically you see changes in people's biology
You see change on their biomarkers your changes in their health and their well and their wellbeing. And this is kind of what's been missing is a way
to sort of have a independent verification system
that analyzes everything, that integrates
with your products easily, and that you can use your phone
and your camera to basically track everything
in two seconds, you have to add everything
into a spreadsheet.
Right, and we wanna be customer aligned, right?
We wanna find that intersection
between capitalism and health
that really looks out for the consumer.
A big thing is we don't ever want to profit
from supplement sales, right?
We need to be just as aligned when you stop taking something
as you are when you try something new.
From the stories that we're hearing too,
supplements for doctors,
the doctors who are prescribing them
and getting involved in the products,
it's becoming like a bit of a revenue stream for them.
And you know, I had a friend who said their doctor came up to them in the products, it's becoming like a bit of a revenue stream for them. And I had a friend who said their doctor came up to them
in the grocery store, didn't ask anything about
how they were doing or whatever, and said,
why'd you stop buying your supplements for me?
And that just doesn't feel right.
That left a really bad taste in their mouth.
So we're gonna keep evolving in the direction
that we think is gonna best look out for customers and be their advocate.
It's okay, and what's also good about it
is you're layering a lot of the science that's hard to get.
What are the interactions between different nutrients?
What are the interactions with drugs?
What are the, you know, there's drug-nutrient interactions
and nutrient-drug interactions.
Sometimes a nutrient will affect the drug function, right?
Like you mentioned, St. John's War,
which can affect medications.
So you have to kind of be aware of all that.
And even if you're a smart doctor,
it's really hard to kind of figure this out.
It was a big Nutrient Supplement database
where it did a lot of this,
but it was, I had to pay $3,000 a year for the prescription,
subscription to this platform.
I had to actually be able to go in and search
and read monographs that were like 30 pages long
on each nutrient and talk about the issues.
I mean, it was really dense and it's hard.
What's crazy is you're getting that, right?
But like the consumers are so much making
their own decisions about the supplements.
So they're never even touching a doctor that knows that.
So there's just so much risk out there with them not,
having that information at their fingertips
in a self-directed way.
And it's one of the things we aspire to get
on the platform.
You're gonna help us with that.
You've already sent me some resources.
And you know, we think it's a big opportunity
to help consumers not make a mistake
when they're doing things on their own.
Yeah, I think that's important.
And you also created something called stacks.
We just touched on it briefly, but I think-
I wanna talk about our stacks.
Yeah.
What do stacks mean?
Look, so stacks is like, to me a stack is like the,
when you're taking a bunch of things together
that have a, for either an individual effect,
like this is my muscle growth stack,
or this is my daily stack,
this is the stuff that I'm taking every day.
And this stuff that's meant to be taken together.
And so, one of the, as I said in the beginning,
the kind of core offering here
was the ability to share your stack
and see other stacks that people are taking.
My stack is on there in public,
your stack is gonna be on there in public.
And I think you can learn a lot from people like you
or people facing the same challenges.
One of the things I love that I came across
a year or two ago was the effects of taurine on longevity.
Two grams of taurine a day,
it's kind of much more than people had thought about before,
but in primate studies showing like really long extensions
to 20% extension, I think, in primates to life,
and a bunch of cardiovascular effects too.
No doctor has recommended me to take tori.
I've had to find that on my own.
You know?
It's amino acid that's really important for many functions
and it's very good for regulating a lot of neurologic issues
and kind of calming, it's a very calming neurotransmitter.
It helps with preventing anxiety.
And I actually use a product,
it's a metagenetic product called TranQor
for a lot of our patients,
which has Toreen, magnesium, B6.
A lot of things are very helpful
in calming the nervous system,
which a lot of people have a lot of anxiety.
And often, part of the problem is we deplete our nutrients
under stress.
We deplete our nutrients because we need more of them
because we're overloaded with toxins.
We need more of them because we eat shitty food
that needs nutrients to be metabolized.
In other words, when you eat food,
it has to be broken down, absorbed, digested,
and actually turned into various pathways
that are important for your body.
And often, if you're not taking the right nutrients,
you're gonna not have the right functions in your body
on a cellular level.
So whether it's CoQ10 or taurine,
these are not considered essential vitamins or nutrients,
but I call these conditionally essential
because of the increased load of stress, of toxins.
It's interesting, when you just stress alone
will deplete magnesium.
So if you're stressed, you're gonna pee out more magnesium.
And guess what, everybody's stressed.
Everyone's stressed.
But this whole concept of sharing and learning
from each other, I remember I was over at your house
for dinner one day and I saw you were taking Timeline,
the Urolithinin A, right?
And you were like, I fucking love this thing.
And I started taking it.
So like learning from each other,
I think is such a big piece of it
for people who are facing similar things
or have similar goals to you.
So the stacks are basically guiding you
if you wanna have a longevity stack
or you have PMS or you have gut issues
or you have, it's like a protocol.
Our protocols are very much designed
for like the crossover between the nutrients
and the-
Health condition.
In the health conditions, right?
So you're gonna be on there with a longevity one,
a brain health one.
That's really exciting to have those protocols on there.
And the stacks to us are what you're taking daily.
And then you can see how they relate to the health goals,
the nutrient totals across all of them.
It's really fascinating to go look at other people's stacks and see how they relate to the health goals, the nutrient totals across all of them.
It's really fascinating to go look at other people's stacks
and see what they're taking.
And you're also gathering information from the users
about their own health issues, their health goals,
their needs, their age, their demographics, and so forth.
Yeah, when you come in, you give us some basic information,
which is gonna be expanded more soon,
and then you go and you scan your existing products
so you can kinda get them in the system, and then we go and you scan, you know, your existing products so you can kind of get them
in the system and then we give you a score, right?
And that score tells you how well your supplements
are aligning with your health goals,
the quality of your supplements,
the cost of your supplements,
and people just seem to do really well with this.
They want a simple, easy to understand number
that they can go move.
Well, I talked to all of my friends who would come in,
they're like, I got a 75, I want it to be an 80.
And so they go and do something,
and the average person is right now making two to three
changes to their product stack based on the sub score.
Which is amazing, these are potential decisions
that could impact them their whole life.
So it's really a way to personalize what you're taking.
Correct.
It's really more of a data driven approach, right?
I think that's what it really fundamentally is.
Like the structured data finally being available
and the ability for us to soon provide recommendations
that span, you know, give you the info
on whether it's an AI-based recommendation,
whether it's coming from Mark's protocol,
whether it's been tailored based on, you know,
some of the data that you provided us
and actually give you like a pretty comprehensive way
at looking at
Why you are making this decision why you are gonna take this and then the end game which we are we are working on is
then to self report back in whether or not it worked and
Once that loop is closed, you know, we think we've completed the journey end to end on supplements and we can just keep improving
So it's almost like you're creating a research infrastructure. I think so. I think it's a huge benefit, I think,
in the world of kind of, you know,
of an AI-driven world too.
There's this kind of blocked-on human concept
I talk about where, like, at some point,
the AI only has enough information
it now needs to get from you,
whether or not you are getting results from this,
whether or not you're taking your pills successfully,
that it doesn't have this information.
And if you can kind of sit at the intersection of that,
I think you found a very, very valuable seam
as the collective intelligence grows
and the individual intelligence gets fed back in.
It's powerful.
I mean, I think, where can people learn about
what we've discussed?
Yeah, so sup.co is the site.
You can go on there.
SUPP.co.
SUPP.co, and if you go to SUPP.CO slash mark,
you'll be able to find a link to the protocols
and Mark's stack on there, which is pretty exciting.
My goodies.
Your goodies.
My recommendations.
And you'll get to see when that gets updated
and when things change, which is very cool.
And look, I think together we're gonna build something,
something better, something better for this industry
and something that I know you've wanted to see exist
for a long time.
And so this is just the beginning.
So there's a website which is sup.co,
there's also an app.
Yeah, the app.
You can get it in the app store,
just search sup.co, you'll see it in there.
And you can go to the site and sign up
and we'll send you the links to it.
You can go to sup.co slash mark.
And then you can share it,
like you can share that data with the community.
You can share it with the community,
you can share it with a bunch of social sharing features too.
You can build customized kind of lists and stacks
that you think work for you and share them to the community,
which is kind of a fun new thing that's on there as well.
So, you know, we have a mix of AI driven data,
clinical data, expert data, like from yourself,
and then users sharing their N equals one stories too.
So it kind of wraps it all up in an easy way
for you to make decisions about your health.
The bottom up data is really interesting
because it's often dismissed.
It's so dismissed.
There's a battle going on between them.
It's like, oh, I took magnesium or I took zinc
or I took, here's what happened to me.
That data is really valuable and an aggregate.
An aggregate.
When you look at all the people putting the data in about how things are affecting them
and what works and what doesn't work, we're going to learn a lot.
We're going to learn a lot.
I think for me, I've learned a lot doing this clinically with tens of thousands of patients
over three decades and doing lots of diagnostics to see what levels of nutrients people have,
what their risk factors are,
and it's so important.
I mean, one of the things where I test for is glutathione,
which is a really important compound
that's involved in detoxification,
that's involved in regulating immune function,
inflammation, it's sort of the most powerful antioxidant
in your system, and there's genetics involved
in what your needs are and how much you need,
and there's a lot of toxic load out there.
And so the body uses it up very quickly,
and it's kind of the final common step
to remove stuff from your body,
like heavy metals or environmental toxins.
If you're urinating the fires or house burned down,
which is tragic,
then you're exposed to all sorts of things.
So how do you up-regulate your body's detox system,
for example?
And acetylcysteine
is a compound that boosts glutathione.
There's also other things like lipoic acid,
and you wouldn't know this unless you test.
Or if you are someone in LA,
I would say here's some things you should take.
Someone has shared an LA fire recovery stack.
Someone has shared that in our community.
That's amazing because I think
there's a lot of value in that.
And also, even for basic things that you know, we think are
Kind of standard in medicine like prenatal vitamins
Most of the ones that are prescription are just full of all kinds of crap
Yeah, and are including nutrients that are not the most bioavailable and not in the right forms don't work as well
And and so women are just unfortunately getting stuff
that is kind of second rate or third rate.
That's a topic that's kind of near and dear to,
while I was building the first,
Sepco, Kelly was pregnant and going through it.
Yeah, and it was hard to get the right information.
We had one saying, only take magnesium oxide.
We had another saying, buy my supplements.
Like it was a wide spectrum.
So we think those issues, menopause issues,
things like that, that we really wanna have
somebody yourself coming on the platform,
another round of experts are coming on
to tackle individual topics that they're the best at.
So you'll be able to see a nice mix of
what the individuals are doing,
what the experts say, and what is the kind of clinical.
And I think one of the things that people
probably have ringing around in their head is,
gee, all these big studies on supplements
show they don't work.
Omega-3, vitamin D, B vitamins, beta-carotene,
this and that.
And so the doctors see these big studies,
they show there's no benefit,
and so they basically dismiss it all.
And so people have a kind of in their heads
this sort of background talk around,
well, my doctor said that there's been big
studies and shows that vitamins don't work.
And there's so many problems with those studies.
One, they don't often measure the baseline level
of nutrients.
So if your vitamin D is fine and you take vitamin D,
you won't notice any change.
But if you don't measure vitamin D in the beginning
or omega-3 fats, if you don't measure if someone's
deficient and you give everybody
a thousand people omega-3 fats,
some might be fine because they eat a lot of fish,
but some might not be.
And so the effect size washes out.
And also when you look at individual problems,
there's a lot of data.
For example, fertility is a big issue,
not just prenatal vitamin,
but fertility is a huge issue, especially for mennatal, but fertility is a huge issue,
especially for men.
Men don't realize that their sperm count,
their sperm quality, their sperm motility,
their ability to be protent is dependent on certain
nutrients like zinc and other things that are really key
for men that they need to be taking in order to optimize
their sperm production if they want to have a healthy baby.
But these are things that people don't know,
and it's all in the scientific literature.
Right, so we've packaged those up, some of those topics, particularly fertility, prenatals, if they wanna have a healthy baby. But these are things that people don't know. And it's all in the scientific literature. Right.
So we've packaged those up, some of those topics,
particularly fertility, prenatals,
they're on the platform with the protocols.
And every one of the recommendations
has an explanation of why.
So you have an ability to really understand why,
and you can pick and choose whether or not
you wanna follow it to exact or adapt it to the fact
that you might know
that you don't need to supplement your vitamin D,
you are okay.
So that's, I think, giving people the ability
to either click the button and go for it
or tailor it to what they know they need
is a unique feature that we have.
To me it's so exciting because it's been a problem
that needs solving for a long time
and no one's really figured it out.
And there were attempts like consumer labs
or some of these natural medicines database,
which is thousands of dollars,
usually only really accessible for physicians
to look at things in detail.
Or some sort of textbook that nobody looks at.
It's like, how do you actually solve the problem
in the marketplace?
And I think Subco is an incredible job.
And I think partnering with Function to do diagnostic tests,
see what's going on, is really helpful.
Because we're gonna be measuring a lot,
we do already measure a lot,
we're gonna be expanding our testing
to do more and more nutrient testing.
Because it's so widespread.
And when people tell me,
oh, you don't need any nutrients because it's not an issue,
I go, well, here's our data.
I mean, I have my data from my own practice
and the other five doctors in my practice,
but we've got 150,000 people now
who've tested their nutrient levels.
And the amount of just frank deficiency,
not insufficiency, but frank deficiency is shocking to me.
And a population I think is probably more health forward.
If they're using function,
they're probably like a little more leaning into their health.
They wanna be healthier, they're probably eating better,
they're probably taking vitamins.
And it was like-
The average CEPCO user takes six products.
If they're correlating the same to your data,
they're taking the wrong thing.
And so you solve that problem.
So I think it's really exciting.
I think we're in this moment where we can really
give people the support they need
to make the right decisions, to understand
that they're not overdosing on certain things,
to understand the quality issues
and where to find the right products.
So you have-
Engaging conversation,
be able to talk to your doctor about it,
be able to talk to your friends about it,
share the things that are working for you,
aggregate N equals one data.
There's a lot of like submissions
and making sense of supplements with SUPCO.
So everybody just go check it out.
It's SUP.CO,
S-U-P-P.CO if you wanna find out what I'm taking, go to SU out. It's SUPP.CO, S-U-P-P.CO.
If you wanna find out what I'm taking,
go to SUPPCO.CO.
SUPPCO.CO.
SUPPCO.CO.
SUPPCO.CO.
SUPPCO.CO.CO.
SUPPCO.CO.CO.
SUPPCO.CO.CO.CO.
SUPPCO.CO.CO.CO.
SUPPCO.CO.CO.CO.
SUPPCO.CO.CO.CO.
SUPPCO.CO.CO.CO.CO.
SUPPCO.CO.CO.CO.
SUPPCO.CO.CO.CO.CO.
SUPPCO.CO.CO.CO.CO.
SUPPCO.CO.CO.CO.CO.
SUPPCO.CO.CO.CO.CO.CO.
SUPPCO.CO.CO.CO.CO.CO.CO.
SUPPCO.CO.CO.CO.CO.CO.CO.CO. SUPPCO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO.CO. You're attacking on the supplement end.
I'm doing it on the biomarker testing, lab testing end.
We're combining forces.
And to me, it's really an exciting moment
where people can start to own their own health.
They can be the CEO of their own health.
They don't have to abdicate or wait
till their doctor learns about nutrition,
which might be 10 or 20 decades from now.
For sure.
I mean, hopefully not.
But actually, Texas, where I live in Austin,
where we are now,
I testified in front of the Senate Health Committee.
And this Health and Human Services Committee
basically introduced a bill called SB 25,
where they said, which passed,
which mandates that Texas doctors
have to learn about nutrition.
Which is amazing.
You're great at the policy stuff, it's amazing.
So, it's like, finally people are talking about it
and I think it's exciting.
I think so all the force are moving towards
people being empowered, people being agents
of their own agency over their own health
and what I like to say is being the CEO of your own health.
So if you wanna do that, you need the data,
the information, you know what you're doing
and actually the truth is I have been taking
a bunch of stuff
and I haven't run it through SAP Co. yet.
And I want to go right now to my medicine cabinet
and everybody's something cabinet
and actually scan everything and see what I'm doing
because it's so fascinating and see where we are.
Cause I think, you know, we all try to figure it out.
Even I try to figure it out
and it's not as easy as you think.
So thanks for what you're doing, Steve.
Thanks for starting this company,
and I look forward to how we kind of unfold this
to the future and empower people, so good job.
Thanks for having me.
It was great.
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