The Dr. Hyman Show - My Experience With Mercury Toxicity

Starting point is 00:00:00 Coming up on this episode of The Doctor's Pharmacy. Traditional medicine completely ignores this. It's like a black hole. They don't test for it. They don't look at it. They don't know how to actually diagnose your body burden. They don't know how to help you detoxify or any of the important things you need to do

Starting point is 00:00:14 to actually resolve this problem. Hey everyone, it's Dr. Mark. Now, I know a lot of you out there are healthcare practitioners like me, helping patients heal using real food and functional medicine as the framework for getting the root cause of the issues. Now, in my practice, this often means looking at lots of internal variables to find the most effective path to optimize health and reverse disease.

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Starting point is 00:01:53 in the light. Right now, Juve is offering all my listeners an exclusive discount on their first order. Just go to juve, J-O-O-V-E dot com slash pharmacy, F-A-R-M-A-C-Y, and apply my code pharmacy for your qualifying order. Again, that's joobb.com forward slash pharmacy, F-A-R-M-A-C-Y, to get your discount. Now, there may be some exclusions, but I'd encourage you to check it out. And now let's get back to this week's episode of The Doctor's Pharmacy. Welcome to The Doctor's Pharmacy. I'm Dr. Mark Hyman. That's pharmacy with an F, a place for conversations that matter. And today I'm bringing you a health bite to improve your health because taking small steps every day can improve your health over the longterm. Now, today we're going

Starting point is 00:02:36 to talk about mercury, not the planet. We're going to talk about mercury toxicity in the environment and how it affects our health. And I'm telling you, I know a lot about this, not because I'm a good doctor, because I was deathly ill from mercury poisoning for many, many years and had to discover the science about it and how to treat it and cure myself, which actually was the way I began to understand the model of functional medicine. Because without that, I think I'd probably be in a nursing home or dead by now. Now, mercury really is probably the biggest source of environmental toxicity that I see in my practice every day. And I've tested tens of thousands of people, probably done 100,000 heavy metal tests in

Starting point is 00:03:19 my career. I've seen more of this than maybe most physicians on the planet. And I can tell you that it's real, that it has real impacts on our health, and that treating it creates real measurable results for people who are sick from it. Now, I've had this, and I don't wish it on my worst enemy, because mercury is one of those compounds that screws up every system in your body. We're going to talk about what the science is about it, what we know about it, and actually how to deal with it. Now, I actually got mercury from many sources. I grew up eating tuna fish sandwiches. I had a lot of dental fillings. I love sushi. And I also lived in China and Beijing during the winter,

Starting point is 00:03:52 which heats its 10 million people living there in their homes with raw coal. And that raw coal is a source of mercury lead and other contaminants. So I was breathing that in every day. I had an air filter, which I cleaned out stupidly and knocked it out the window and breathe in the concentrated soot, which was full of mercury. And when I developed the symptoms, it just hit me all of a sudden. I was basically fine. And then something tipped the scale. I think it was an intestinal infection. And because of my own personal genetics, which make it hard for me to detoxify, and because of my own personal genetics, which make it hard for me to detoxify, and because of this high load of mercury I had in my body, I all of a sudden went into severe collapse. I couldn't think. I was fatigued. I couldn't sleep. I had muscle pain, twitches, muscle damage. I had severe

Starting point is 00:04:40 digestive issues because mercury interrupts all the digestive enzymes and you had diarrhea for years. I developed food sensitivities, depression, anxiety. I mean, I really didn't know what the hell was going on with me for a number of years until I actually did some testing and I found I had huge levels of mercury. I've done, again, I said probably 100,000 of these tests and about 10,000 or more people. And I can tell you that I had probably maybe in the top 10 or 20 of all the highest tests I've ever seen. Now, I've seen this in so many of my patients who suffer from all sorts of things, from chronic fatigue and fibromyalgia to depression, anxiety, obesity, dementia, Parkinson's disease, cancer, heart failure, heart disease, so many different issues,

Starting point is 00:05:30 many gut issues. If we don't understand how to diagnose this, if we don't understand how to treat it, we're going to be leaving so many people in the lurch suffering needlessly. Now, traditional medicine completely ignores this. It's like a black hole. They don't test for it. They don't look at it. They don't care about it for some reason. Occasionally, they will do a blood test for mercury levels, and you'll see a whole blood mercury, and it may be high from fish. And they go, oh, stop eating so much tuna fish. But that's about the extent of it. They don't know how to actually diagnose your body burden. They don't know how to help you detoxify or any of the important things you need to do to actually resolve this problem. So I'm going to give you kind of a rundown on the state of mercury that we know now and a plan to actually help

Starting point is 00:06:05 reduce your exposure and also heal and get rid of mercury from your body. Now years ago I went to a conference, it was called the Impact of Mercury on Human Health and the Environment and it was held at Tulane University School of Public Health in Tropical Medicine in New Orleans. This was a conventional medical conference, okay. I want to sort of break down what was there, but it was an amazing group of scientists, policymakers, environmental scientists, toxicologists, biochemists, journalists, academic doctors, practicing doctors, dentists, everybody was there. And we tried to make sense of the environmental impact, toxicology, the basic science,

Starting point is 00:06:38 the public policy implications, the health implications of one of the least studied and probably the greatest potential threats to our long-term health, which is mercury. Now, mercury levels were not high in our environment until the Industrial Revolution, until we were able to dig coal out of the ground, until we were able to actually burn it, until we developed the fossil fuel industry. All that led to the rise in mercury in the atmosphere, which actually polluted our oceans and led to fish being contaminated with mercury. And the kind of rest of the story is pretty clear. Now, there were episodes of volcanic eruptions and things like that in the past. And you can actually see in different snow melts when they'll do like, for example, ice cores on glaciers, and they can say,

Starting point is 00:07:17 oh, there was a volcano in like, you know, the Philippines in 1805. And we can see that mark in the snow. But it's really been a 30-fold increase over the last 100 years in mercury in the environment. 70% of it's from human sources, and particularly in the last 40 years during the last period of great industrialization. And it comes from coal-burning and coal-fired industrial plants, cement plants, chloralkalite plants. They actually use this in the making of plastics, pesticides, PVCs, pipelines, and more. So basically, there was a reduction in industrial mercury emissions over the last 10 years, but I think it's a small amount compared to what we're really

Starting point is 00:08:06 dealing with in our environment. Now, what is sort of the deal when it comes to the risk of these problems? Well, it's kind of an increasing risk with increasing dose. Now, there is an exception for that. If you actually are dealing with immune effects, and we call this immunotoxicity. In other words, the role of environmental toxins in causing autoimmune disease. These are in fact called autogens. It's a well-described phenomenon in medicine now. And mercury doesn't have to be hugely high to actually cause an autoimmune response. So it's important. But there really is no safe level. Like what's the normal blood level of mercury? Well, on your lab test, it may just say zero to 15.

Starting point is 00:08:47 But what's the normal biological requirement for mercury? Zero. There is no normal level of mercury in the blood. It should be zero, okay? There's no need for mercury in the body. Now, there is a lot of data about the risks. Some of that comes from, for example, research in the Seychelles Islands where they looked at kids and how they basically were affected. And they had a lot of

Starting point is 00:09:16 fish in their diet and they had very mostly reef fish, which have low levels of mercury. On the other hand, the Faroe Islands where people were eating whale blubber, which is hugely high in mercury, were three parts per million. There, they found extremely high levels in the umbilical cord blood, and it correlated with reduced performance in neurologic testing in over 900 mother-infant pairs. So they looked at mothers and infants. They checked the level of mercury in the cord blood. They looked at neurological testing, and there was significant effect. And the dose, it sort of relates to the impact, right? So the severest symptoms, you know, occurred with higher doses. And you want to make sure that, you know, you have

Starting point is 00:09:54 really a look at what your levels are. When you see the effects, you know, there were developmental effects and walking, talking, decreased performance on neurologic tests. So it's really important. Now, the problem is testing. When we look at testing, doctors will look at blood levels, but it's what doctors typically check. But unless you've been eating fish with mercury in it over the last 90 days, it may not show your true body level. For example, most mercury is clear from the blood within 90 days. And some of it's excreted in the urine, processed by your liver, but most of it is actually sequestered or stored in your organs, in your muscle, in your brain, in your liver, in your kidneys. That's where it goes. And when you eat, for example, tuna, what are you eating?

Starting point is 00:10:41 You're eating the muscle of the fish and that's where it's stored. So unless you actually do a challenge test where you take a chelator, which binds to the mercury in your body, pulls it out and collect your urine for six hours, you're really not getting a valid look at what your body burden is. And unfortunately, this is not tested by conventional doctors. They might do a 24-hour urine mercury test. That's helpful if you had acute exposure in a, for example, industrial plant or something, but it's not going to tell you what your long-term body accumulation is. So, you know, mercury basically accumulates in muscle and accumulates in fat. And so basically blood levels aren't the best test for your body burden. There's another form of mercury called the inorganic mercury. Now, methylmercury is the

Starting point is 00:11:24 most predominant form that comes from fish, but inorganic mercury is primarily from fillings. We call these silver fillings. They're not silver. They're mostly mercury. And it's cleared from your blood and stored in your tissues. And it can be converted to methylmercury in the body. And it can actually end up leading to all kinds of neurologic issues, everything from dementia to ADD to autism. And so you really need a proper diagnostic test to look at it. So the question is, how do we get mercury in our bodies? Well, it's a lot of different sources. It can be from mercury vapor in the air if you live near a cement plant or a coal burning plant. It can be from water, from contaminated water, from fish, as I mentioned, from your dental fillings.

Starting point is 00:12:06 There's ethyl mercury in vaccines, thimerosal. Most of it's been taken out, but there's still a few vaccines like the flu vaccine that has it. It can be occupational exposures. It can be from home exposure. You break a fluorescent light bulb. You have a thermostat, you have batteries,

Starting point is 00:12:20 red tattoo dye if you got tattoos. Splint lightning creams can cause it uh there used to be more and over the counter products less so now but it used to be in contact lens fluid and neosynephrine which you use for cold sinuses so you know 80 of it is is basically um uh you know coming from the source of fish is primarily what's going on. It's basically coming through your gut. You do inhale it if you're exposed, but it's not as much of a big issue. Now, once it gets to your body, it goes to the kidney, it goes to your brain, it can be transferred to the baby through the placenta. So a lot of kids are born pre-polluted. The only way out of your body is

Starting point is 00:13:06 through urine, your feces, your breath, and breast milk. So the problem that mercury causes in your body is it binds to enzymes. It binds to what we call the sulfur groups of enzymes. And this is kind of on most enzymes. And it's in the mitochondria and other chemical binding sites. And it basically jams up your biochemical machinery, which is why it caused such widespread effects. Now, we know, you know, with big exposures, we've documented the consequences like the Minamata Bay exposure where there was, you know, effluent from factories going into this

Starting point is 00:13:42 bay and then the people in the town ate the fish and the kids ate the fish. They had terrible birth defects. They had pink disease or acridinia. Also, teething powder back in the day in the 30s, 40s had mercury in it. It was called calomel. It was something used in medicine way back in the 1800s. I think it's what the Lewis and Clark expedition used to treat everything from syphilis to chronic infections.

Starting point is 00:14:08 We've heard of a Mad Hatter syndrome. The Mad Hatter from Alice in Wonderland, the Hatters used felt to actually make the hats and the felt was made stiff with mercury. And so, you know, it's also in fungicides and has been, you know, from grain exposures to contaminated pesticides uh, uh, pesticides, uh, grains.

Starting point is 00:14:27 Um, so it's, it's really a problem. Now it mimics so many different problems. So you think, you know, you have depression, you're obese, you have diabetes, you have, you know, dementia, you have autism, you have ADD, you have whatever, an autoimmune disease and you think, oh, that's all what they are. But actually they may be caused by mercury. We know that the symptoms of mercury poisoning in babies is very, very similar to the symptoms of autism. This is very well described. It's called erythrism and it's an issue and it leads to shyness, mood swings, insomnia, memory issues.

Starting point is 00:15:08 A lot of neurologic symptoms are caused by mercury, including Parkinson's, been linked to a tremor, loss of balance, loss of hearing, tunnel vision, slurred speech, headaches, sexual dysfunction. Really, really important. It can affect the gut like it did for me, causing diarrhea, vomiting, nausea. It can cause skin issues. So it's really quite a problem.

Starting point is 00:15:29 We want to make sure we get rid of the mercury. So one of the controversies is about mercury fillings. I think it's less so. I think Canada is mostly banned. I think finally the FDA said it shouldn't be used for pregnant women and children. I wonder why it's okay for the rest of us i don't really think it is but basically it's clear that the the fillings will through chewing and through the ph of your mouth depending on the microbiome of your mouth can vaporize and release large

Starting point is 00:15:55 amounts of mercury over time uh from brushing grinding um and so you know that that can be a factor now there was a large study um where they at, that was published in JAMA, found really no correlation between mercury fillings and behavioral issues in kids. However, there were a lot of problems with that study. First, it was a short study. And two, they didn't look at the genetic differences in these kids. And there was really differences in the kids who had impaired detoxification pathways. So if you redid the analysis of the study and you said, okay, who are the kids who are poor detoxifiers versus good detoxifiers? The good detoxifiers seem okay.

Starting point is 00:16:41 The ones who were bad detoxifiers had a seven-year developmental delay. So if they were like 18, it was like they were 11, right? So that's a real, real problem. Now, it can take a long time to get rid of mercury from your body, up to 18 years to clear half the dose of mercury. And it comes up very, very slowly once it gets in. So you've got to learn how to actually reduce the exposures. And I think when you look at people with fillings, the data is really clear. They have higher blood mercury. They have three to five times more mercury in their urine.

Starting point is 00:17:15 They have two to 12 times more mercury in their tissues than those people without amalgam fillings. There was one study I saw in sheep and monkeys where they basically put in fillings and then they actually didn't see terribly high levels in their blood because it's inorganic mercury, but their tissue levels were high. And when they did brain biopsies, they found a lot of this in the brain. They've even done corpse studies, autopsy studies on people with Alzheimer's.

Starting point is 00:17:38 And the ones who had the most filling surface area had the higher risk of Alzheimer's. So it's really quite an important thing. Now, urine levels is how often doctors check. But again, it just looks at what's really your current exposure. So you really got to kind of do the proper testing. There are now tests, Quicksilver Scientific has a test called the QS Tri-Test, where it looks at mercury from inorganic sources or methylmercury from fish, so you can get a sense of where it's coming from. But I've seen, for example, patients who have fillings for decades who have high levels. So you know, I've had it for 30 years.

Starting point is 00:18:16 I've had the fillings. It's probably not a problem. Not true. They still vaporize. Now, I see more and more changes in many countries like germany and canada and europe where they basically have banned these fillings they can't get them anymore uh you still can do in the united states but it's most dentists actually don't do them anymore they just kind of quietly have switched over um i don't know why by the way uh you should ask your dentist this you know when

Starting point is 00:18:40 according to the epa environmental protection agency if if you take fillings out of somebody's mouth, you can't throw it in the garbage. You have to dispose of it in a specific way as if it were a toxic waste. So ask your dentist if he says they're fine. Say, why is it okay to put in my mouth, but it's not okay to throw in the garbage? I think you should think about that. So I think the data on this is pretty clear. Again, many, many scientists are on board with this and many governments are now finally,

Starting point is 00:19:12 you know, are very clear that this is a problem. So I think kind of we need to really get serious about getting these feelings out of people's mouth safely. And that's a whole nother conversation about how to safely remove them. Because you can't just go in there and drill. You've got to put a neutral dam in. You've got a high-speed suction.

Starting point is 00:19:32 You've got to make sure you don't swallow it. You don't breathe in the vapor. The dentist should be wearing a mask, you know, a gas mask, basically. So you have to find a special dentist. And there's a website, iaomt.org. We'll put all this to the show notes where you can get a

Starting point is 00:19:46 dentist who's been trained how to safely remove mercury. So I think this is important. Now, let's talk about genetics here because I think not everybody's affected, right? I've seen people with a mouthful of fillings. Some guy was 70 years old. I'm like, this guy's going to be in trouble, but it turned out he was okay because he was able to really detoxify. Unlike me, I'm not great at detoxifying. So I tend to have increased absorption of mercury, decreased ability to eliminate mercury. I have glutathione genes that are problematic. Glutathione is the body's main way of getting rid of mercury. It's a sulfur-based molecule in the body. It's from three amino acids, cysteine, glutamine, and glycine. And it's ubiquitous.

Starting point is 00:20:28 It's critical for longevity, for health, and for detoxification. It's an antioxidant, anti-inflammatory. And you need it to get rid of mercury. Now, people who have high mercury tend to have depleted glutathione because their body's working overtime to get rid of it. So you need to do things to boost glutathione. But I have genes that make it hard for me to make glutathione and I end up having more load of mercury given there's a problem.

Starting point is 00:20:52 There's also interesting data on ApoE genes. These are genes that are Alzheimer's risk genes or cardiovascular risk genes. And if you have ApoE4, you tend to not be able to eliminate mercury because it doesn't have a cysteine or sulfabary amino acid on the apolipoprotein 4 genotype. And so that basically means that if you have this, you're at high risk for not only Alzheimer's, but many other cardiovascular risk diseases, and you end up being unable to excrete it. In one study, I think it was in Australia, they gave people a chelator, DMPS, who had ApoE4. And compared to non-ApoE4 patients, they had much higher body burdens of mercury. So this all sounds pretty depressing. But the good news is that we can reduce, one,

Starting point is 00:21:40 our exposures, and two, increase our ability to eliminate it. And so when I see someone coming into my office, you know, I check their blood pressure, I check their heart rate, I get their weight, I get all these important things, get their cholesterol, right? I check mercury on and heavy metals on every single patient who comes in with any health problem because it can be a great mimicker of all sorts of diseases. And I want to make sure that if they have it, that I treat it. And if they don't, that I have eliminated from my diagnostic possibilities of what's causing the problem. Now, the main ways we expose again is contaminated fish in our fillings. So you want to make sure that you get rid of the large fish in your diet,

Starting point is 00:22:22 like tuna, swordfish, shark, tailfish tailfish halibut orange roughy i mean the list goes on and on there's some great resources the nrdc has a wallet card which is low medium and high mercury fish environmental working group has a has a great resource for how to reduce your contamination from fish that's ewg.org there's the monterey bay health watch which so there's a lot of great sources and there's actually great companies that now doing regenerative aquaculture which are raising great fish with low toxin levels uh the company i like is called seatopia.fish um put that in the show notes that's c-e-a-t-o-p-i-a.fish and they have great delicious delicious-tasting fish. So really important. Now, you can check your blood level, but again, remember, that'll only detect your recent exposures. You can check your hair.

Starting point is 00:23:13 Again, that gives you a partial picture because it doesn't check any mercury from filling, it's just from fish. And again, as I've said, once your hair grows out, if you haven't been exposed, let's say you ate tuna fish for 10 years then you stop for two years it would probably be none in your hair or none in your blood but you could have a ton in your body so the only way to really detect it is using a chelating drug called dmsa or dmps which is not so available in the u.s and it binds the mercury like fly paper it's got sulfur in it. It should only be done by doctor. It involves taking one dose of medication followed by a six-hour urine collection. And then

Starting point is 00:23:51 you see how much comes out. And it's the most reliable way to see what your body burden is. Again, this is not a conventional test that most doctors do. It's not really well-recognized. People say it's problematic, but they go, oh, well, well yeah of course you're taking a chelator but no if there's no mercury and i i had patients with no fillings who are vegan who i do the test on who never ate fish who don't have any fillings who don't live near a cement or coal plant and they have zero heavy metals in their body for mercury it's quite amazing so it's something i've seen over and over again i think there needs to be more research, but again, there's nobody funding this data. Now, if you are sick and you have a high level of methylmercury or ethylmercury from the blood test, you can see it's probably a good idea to see a dentist and get your feelings out safely. There's a lot of ways for food you can actually improve your body's detoxification capacity. You

Starting point is 00:24:41 can take cruciferous vegetables, the broccoli family, and that boosts glutathione. Garlic and onions also do the same thing. They have sulfur in them. You can use various things like cilantro, which I've seen people juice cilantro, can help their bodies eliminate them. You want to make sure you're taking plenty of fiber and having regular bowel movements to bind and excrete the metals. You want to make sure you're drinking plenty of water. You want to do saunas, which help to eliminate the heavy metals and toxins through your sweat. But you also may need to take a chelating drug or do other things as well. There's some great supplements that can help that boost glutathione like N-acetylcysteine, lipoic acid. Things like selenium and zinc are

Starting point is 00:25:20 also important for activating your body's metal detox pathways. You need the right methylating vitamins, B6, B12, folate. So I've written a lot about this. We're going to link to articles that I've written about how to identify source of mercury, how to optimize your body's own detoxification systems. But it's really, really important if you have any type of chronic illness and you have any type of exposure that you get this properly checked, that you work with a functional medicine doctor to get this properly treated, and you will see profound benefits. I went from basically being barely able to function to being severely ill and having

Starting point is 00:25:57 all sorts of immune issues, cognitive issues, digestive issues. I had severe muscle damage with elevated muscle enzymes. I was a mess. And it took many years for me to learn about this, to detoxify myself. But now I've learned how to do it a lot faster. And I would say it's one of the most satisfying things I do is treat people with these problems. And I've seen people reverse obesity, depression, autism, ADD, Alzheimer's even, poor metabolic health, autoimmune diseases, Crohn's disease. I mean, the list goes on and on and on. I remember one guy had ulcerative colitis. I tried everything I knew how to do. Finally, I did his heavy metal test. He had super high levels. We chelated him and supported him with IVs and other things like glutathione, and he completely reversed his

Starting point is 00:26:45 ulcerative colitis. So I see these stories every day in my practice, and I encourage you to not give up. You need to go find somebody who can work with you. I would check ifm.org for a doctor in your area, but recognize that this is a big problem. It leads to many conditions that are often misdiagnosed as something else and in order to properly deal with this you need to work with a trained functional medicine doctor to help you identify the source identify your body burden and create a roadmap for applying the right therapies in the right way at the right time to help your body detoxify so i hope you've enjoyed this health bite uh it's a lot of information but i think it's important. And I think you can limit

Starting point is 00:27:25 your exposures. You can get mercury out of your body and it'll help you live a long, vibrant, healthy life. And that's it for today's health bite. I hope you liked it. If you loved it, please share with your friends and family on social media. Tell us how you've dealt with your heavy metal toxicity. What can we learn from you? Maybe you've discovered a way to help get rid of it. And also subscribe wherever you get your podcasts and we'll see you next time on The Doctor's Pharmacy. Hey everybody, it's Dr. Hyman. Thanks for tuning into The Doctor's Pharmacy. I hope you're loving this podcast. It's one of my favorite things to do and introducing you all the experts that I know

Starting point is 00:28:01 and I love and that I've learned so much from. And I want to tell you about something else I'm doing, which is called Mark's Picks. It's my weekly newsletter. And in it, I share my favorite stuff from foods to supplements to gadgets to tools to enhance your health. It's all the cool stuff that I use and that my team uses to optimize and enhance our health. And I'd love you to sign up for the weekly newsletter. I'll only send it to you once a week on Fridays, nothing else, I promise. And all you do is go to drhyman.com forward slash pics to sign up. That's drhyman.com forward slash pics, P-I-C-K-S, and sign up for the newsletter. And I'll share with you my favorite stuff that I use to enhance my health and get healthier and better and live younger, longer. Hi, everyone. I hope you enjoyed this week's episode. Just a reminder that this podcast

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The Dr. Hyman Show - My Experience With Mercury Toxicity

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