The Dr. Hyman Show - The #1 Anti-Aging Tool You’re Ignoring (Hint: It’s Free and Happens at Night)

Episode Date: April 14, 2025

Sleep is not just a luxury—it’s a foundational pillar of health that influences nearly every aspect of our well-being. Sleep deprivation doesn’t just cause fatigue; it disrupts hormones, drives ...inflammation, damages metabolism, and accelerates aging. From the gut microbiome to stress hormones like cortisol, sleep is deeply intertwined with brain, immune, and metabolic health. Yet our modern world—filled with late-night screens, ultra-processed foods, and chronic stress—works against quality rest.  In this episode, I discuss, along with Dr. Matt Walker and Shawn Stevenson, why we need to address sleep as a core health priority to unlock healing, prevention of chronic disease, and renewed vitality. Matthew Walker earned his PhD in neuroscience from the Medical Research Council in the UK, and subsequently became a Professor of Psychiatry at Harvard Medical School. He is currently a Professor of Neuroscience and Psychology at the University of California, Berkeley, and director of the Center for Human Sleep Science. Matt’s research focuses on the effect of sleep on human health and disease, brain, and body. He has published more than 100 scientific research studies and has received numerous funding awards from the National Science Foundation and the National Institutes of Health. Matt has given a main-stage TED Talk that has been viewed over 13 million times, has also created several TED Miniseries on sleep, a MasterClass series on sleep, and is author of the New York Times bestseller, Why We Sleep. Matt is also the host of the 5-star-rated, The Matt Walker Podcast. Shawn Stevenson is the author of the USA Today National bestseller Eat Smarter, and the international bestselling book Sleep Smarter. He’s also the creator of The Model Health Show, featured as the number #1 health podcast in the U.S. with millions of listener downloads each month. A graduate of the University of Missouri–St. Louis, Shawn studied business, biology, and nutritional science and became the cofounder of Advanced Integrative Health Alliance. Shawn has been featured in Forbes, Fast Company, The New York Times, Muscle & Fitness, ABC News, ESPN, and many other major media outlets. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: How to Optimize Your Sleep with Dr. Matthew Walker How To Stay Asleep And Sleep More Deeply Hack Your Sleep

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Starting point is 00:00:00 Coming up on this episode of the Dr. Hyman show. And I often tell people that you can overeat your weight fat. You can under exercise your weight fat. You can under sleep your weight fat and you can also overstress your weight fat. Stanford university, they found that just one night of sleep deprivation has a traumatic effect on suppressing leptin.
Starting point is 00:00:16 Just one night of sleep deprivation, we're seeing about 14% reduction in glucose reach in your brain. What if I told you there's a mineral that acts like a spark plug for your body, powering your brain, heart, muscles, and even your mood, and most of us are running on empty? That mineral is magnesium and it's involved in over 600 biochemical reactions, from regulating stress to boosting energy, sleep, and digestion, but not all magnesium supplements are created equal.
Starting point is 00:00:42 That's why I recommend magnesium breakthrough by bioptimizers. It's the only full-spectrum magnesium supplement that includes all seven forms of magnesium your body needs to function at its best. Most magnesium supplements only give you one or two forms, but Magnesium Breakthrough ensures maximum absorption so you get real benefits, better sleep, improved mood, reduced stress, and enhanced recovery. I take it every night to wind down and support my body and I highly recommend it. Try magnesium breakthrough today and feel the difference. Go to bioptimizers.com slash Hymen
Starting point is 00:01:11 and use code HYMAN10 for 10% off your order. Now before we jump into today's episode, I'd like to note that while I wish I could help everyone by my personal practice, there's simply not enough time for me to do this at scale. And that's why I've been busy building several passion projects to help you better understand, well, you. If you're looking for data about your biology,
Starting point is 00:01:29 check out Function Health for real-time lab insights. And if you're in need of deepening your knowledge around your health journey, check out my membership community, the Hymen Hive. And if you're looking for curated and trusted supplements and health products for your health journey, visit my website at drhyman.com for my website store for a summary of my favorite and thoroughly tested products. Human beings are the only species that will
Starting point is 00:01:51 deliberately deprive themselves of sleep for no apparent good reason. Like doctors, you mean? And like doctors, exactly. But what does that tell us? That tells us is that mother nature has never had to face this challenge of sleep deprivation. So no wonder there are no safety nets in place.
Starting point is 00:02:07 So no wonder that we firstly go down very quickly, biologically, in terms of our health. But also, don't forget that that is such a rare circumstance, that when it happens, when the brain starts to sense, I'm not sleeping enough. Now, it doesn't know why, because we're watching Netflix. It just says, red alert, break glass in case of emergency. I'm not going to care about you, the people that I love.
Starting point is 00:02:35 I've got to go into essentially low battery status and take care of myself. So you lose your empathetic sensitivity. We looked at doctors, and there's great study from a team in Israel, too, and what they found was that they started to prescribe less, and it was necessary, less pain medication for their patients
Starting point is 00:02:53 the more sleep deprived they were. Why? Because they lost their empathy. They did not care. And so patients are suffering. They are more sort of ensconced in nociceptive, you know, drench of pain, because the doctors just don't see it. I mean, I remember, honestly, because I was in, you know,
Starting point is 00:03:15 residency and working hard, and I was living babies, working as a family doctor. I mean, I spent many, many, many nights not sleeping at all. So not even having two hours of sleep, just not sleeping, and working 36 hours straight. One shift was 60 hours. And I remember how I would feel. And I was like, you know, you force yourself.
Starting point is 00:03:37 At first, you're like, your body's just like shutting down. And then you learn how to caffeinate and override your body's sense of needing to sleep. And then you kind of will yourself through. And you know, the idea is, idea is, you're a doctor, you have to be ready to go at any time, you have to deal with crisis, and pick the right answer, and do the right thing,
Starting point is 00:03:52 and be able to function in the worst conditions, which is kind of like a Navy SEAL. Yeah, it's almost like a hazing that, well, we went through it, and you're gonna have to go through it. But it's horrible. My daughter's in medical now, and she called me one morning after one of her first shifts
Starting point is 00:04:06 where she had to do this. She was like, I don't wanna do this. This is horrible. And I think it's a, you know, the sleep deprivation crisis in America, it's sort of parallel to the lack of exercise, the crappy diet we have, it's degrading our health. And you combine all those things together
Starting point is 00:04:23 with all the chronic stress, it's no wonder we're the sickest and fattest nation in the world, pretty much. And if you look at the curve, the decline in sleep over the past really 70 years for which we have good data, and if you look, for example, at the rise in obesity over the same duration of time, those two things go in opposite directions. As sleeping is coming down, obesity is going up.
Starting point is 00:04:44 And we know that a lack of sleep changes your appetite hormones. Those two things go in opposite directions. As sleeping is coming down, obesity is going up. And we know that a lack of sleep changes your appetite hormones. It changes your ability to dispose of food and specifically regulate your blood sugar. So you are more obesogenic in terms of your profile of weight gain. Crave more carbs and sugar.
Starting point is 00:04:58 I remember that. I mean, when I was like, two in the morning, I'm working the ER, I'm exhausted, I'm like, give me the sugar. Yeah. Where's the sugar? That's all you want. And that's exactly, it's not just that you eat more,
Starting point is 00:05:09 which you do, it's what you eat, that's the problem. You go after the heavy hitting stodgy carbohydrates, simple sugars, and you shy away from the sort of, you know, the leafy greens, the nuts, and the good proteins, because you are just on a junk food binge. Well, you want to get energy. Yeah.
Starting point is 00:05:26 And you want it quick. Yeah. Yeah, I remember that. So, you know, the question is, you know, is the sleep deprivation a big part of the cause? And because of the decline in sleep, it seems like it may, because I've read these studies, they take young college kids,
Starting point is 00:05:40 and they basically sleep deprive them, and they're healthy, but then the ones who get sleep deprived just eat more, and they're healthy, but then the ones who get sleep-deprived just eat more and eat more sugar and carbs. That's right, and you can see that same replication of failure across multiple organ systems. So for example, I take a young, healthy set of males, I limit them to let's say four or five hours
Starting point is 00:05:57 of sleep for five nights. They will have a level of testosterone, which is that of someone 10 years their senior. So I can age a healthy young of someone 10 years their senior. So I can age a healthy young man by 10 years by short sleeping them for a week. You can take people who have perfectly regulated blood sugar, no problems with their blood glucose
Starting point is 00:06:14 whatsoever, put them on that same regiment of four or five nights of short sleep, and at the end of it, someone like you would look at their blood work and you would say, you are bordering on being pre-diabetic right now. Again, that's within the space of days. Days, yeah. So you can, so I think it's again, a demonstration to us
Starting point is 00:06:37 that sleep, we don't have any real wiggle room. It's not negotiable. Yeah. So in terms of the reasons we're not sleeping, and it's clear we're not sleeping. Is it because we're too busy, too stressed, we have too many obligations, is it because we're watching too much Netflix,
Starting point is 00:06:54 is it because we're scrolling on our phones, is it some other factors? What are the main factors that are leading to the sleep deprivation crisis and are causing, I last I heard was like 70 million Americans having serious sleep issues. Yeah. Right?
Starting point is 00:07:07 What are the main causes? All of the above plus more. So there's not necessarily just one cause. Let's start at the hierarchical government level. There is no First World Nation that I know of that has had a major public health campaign regarding sleep. Why not?
Starting point is 00:07:22 We've had it for drunk driving. Productivity. We've had it for safe sex, we've had it for, you know, all of these different things, but there's nothing there for sleep. And yes, you could argue from a cynical perspective. It's because we want you, you know, from a capitalist society, we really want you to be doing two things. You're either, you know, producing things or you're buying things or you're consuming things, and if you're asleep,
Starting point is 00:07:45 you're not doing either of those two. So you could argue conspiracy. I don't think it's that. But, and we've actually, I've actually just recently started a public charity, a foundation specifically designed for global sleep education. Take it a step down.
Starting point is 00:07:58 There is the World Health Organization that I spoke to recently, there is no educational module for children translated into 37 different languages across different age ranges that educates them on the importance of sleep. So no wonder there is a parent-to-child transmission of sleep neglect.
Starting point is 00:08:15 We have to change that too. Some of it is about education. The second part is mental health. We have a rising tide of anxiety in society. People are so stressed and we get people coming into the center at UC Berkeley and they all say, I am so tired, I am just so tired, but I'm so wired that I can't fall asleep.
Starting point is 00:08:38 This tired but wired phenomenon. So the anxiety epidemic is causing sleep problems. We've also got... And that's adrenal too, right? That's the cortisol rise at night. It's cortisol rise at night. It's because of that, what we call the HPA axis, the sort of the cortisol descending chain. It's also because the nervous system
Starting point is 00:08:57 almost is forced into a locked position of the fight or flight branch, what we call the sympathetic nervous system, which is anything but sympathetic, it's very agitating. And we cannot sleep when we are wired into the fight or flight branch. We have to switch over to the quiescent branch, the parasympathetic.
Starting point is 00:09:16 So I think those two factors, the adrenal sort of nation, as it were, together with this fight or flight stance of the nervous system, is a royal roadblock to good sleep at night. I think it's one of the biggest factors. Um, we've then also got the combative forces of entertainment and social media, which are on the, of course, consuming best of every time. I'm trying to get my wife to stop scrolling on X
Starting point is 00:09:38 every night to figure out what's happening in the world. I'm like, why are you doing that before? And it's the worst time because on, in this modern era, we're constantly on reception. Very rarely do we do reflection. every night at Faragall is happening in the world. I'm like, why are you doing that before I'm dead? And it's the worst time because in this modern era, we're constantly on reception. Very rarely do we do reflection. And the only time we do reflection is when our head hits the pillow.
Starting point is 00:09:53 And that is the worst of times to do reflection. Because when you do that, you start to ruminate. When you ruminate, you catastrophize. And when you catastrophize, you're dead in the water for the next two years. Because, you know, everything seems twice as bad in the dark of night than it does in the light of day. And if we're doing that right before bed.
Starting point is 00:10:15 So I think there are issues there. Sleep disorders are on the rise. Insomnia, which I think is a consequence of the anxiety and the stress. You know, I often think that insomnia is the revenge of things that we've not processed during the day and got resolution to. We've got sleep apnea, snoring.
Starting point is 00:10:33 I think that's heavy snoring or can be an indicator of that. That's certainly comorbid with diabetes and also obesity. So I think you've got all of this collection of factors together with the stigma that we described earlier, which is, well, I'm not really that proud of sleeping more. Why should I be? Because society doesn't reward it. You know, it's the type A, the early bird catches the worm. Maybe that's true, but I would say based on the data,
Starting point is 00:11:02 the second mouse gets the cheese. And what's strange is that we... I heard the data, the second mouse gets the cheese. Yeah. And what's strange is that we... I heard that one. Second mouse gets the cheese. Ha ha ha. But I find it funny that we chastise people who wake up late as being lazy. But we never say, oh, you go to bed early,
Starting point is 00:11:18 you're lazy. Yeah. Well, that's night owl and that's morning lark, it's not your fault. So I think there are a whole collection of conspiring factors that together conflate to this enormous sleep challenge that we have in society right now. Yeah, there's a couple things I want to drill down into,
Starting point is 00:11:34 because I think that in your article, you talked about gut dysbiosis and gut dysfunction and the microbiome is playing a role in sleep, which is something that most people have never thought of. And it was a substantial part of your article. And we'll link to the article in the show notes, but it was interesting to me because I think that inflammation plays a big role in sleep disruption.
Starting point is 00:11:56 And the gut microbiome plays a role. And also environmental toxins may play a role. Nutritional deficiencies may play a role. And there are things, hormonal dysregulation plays a role. And these are things that are not really well investigated by conventional doctors and not well understood. But sometimes it's as simple as just giving someone magnesium because 45% of the population is low on magnesium
Starting point is 00:12:18 and you give them magnesium at night and they're sleeping like a baby. Right. Or their iron's low and they have iron deficiency and people don't realize that low ferritin is correlated with sleep. Yeah, restless leg syndrome. Restless leg syndrome and sleep deprivation and nobody checks that.
Starting point is 00:12:31 So can you kind of walk us through some of those unusual kind of things that may be contributing besides the social factors and the stress and the adrenal and the things that we just talked about? Yeah, I think all of those factors that you just described will all feed into gut dysbiosis. And there is, I think, a bidirectional, and this is what we spoke about in the article,
Starting point is 00:12:56 a bidirectional relationship between your gut health and your brain sleep health, meaning that when your gut is in balance with that sort of collection of the flora and the fauna in your gut microbiome, it can send a health-related signal through the nervous system by way of a major highway that connects your gut to the brain called the vagus nerve.
Starting point is 00:13:19 And that can help. That's not like Las Vegas, that's V-A-G-U-S. That's for relaxation, that's the relaxation nerve. That's the relaxation nerve, but it's also a major informational highway, bi-directional communication path between your brain and your gut. That's how we think that the gut can influence the brain.
Starting point is 00:13:36 And that's how we think that if you get the gut right, it may be a new approach to a sleep aid, because then you can get the brain right. And it works in the opposite way, which is that when you are sleeping well, it can communicate a signal for improved gut health through the vagus down into the body. But when you are not sleeping well, and there's been some great studies, for example,
Starting point is 00:13:59 in the extreme with jet lag, my goodness, do you see that when the brain becomes deficient in its sleep through this communication pathway, in the extreme with jet lag, my goodness. Do you see that when the brain becomes deficient in its sleep through this communication pathway, you will get significant gut dysbiosis. And many people will tell you one of the things that happens when I'm jet lagged is that my tummy is just off.
Starting point is 00:14:17 Oh my goodness, things don't go well for me. And I don't quite understand why. I'm eating the same things, but it's probably because of this gut dysbiosis caused by a lack of sleep. Interesting. You know, I'm wondering, and this thought popped in my head,
Starting point is 00:14:30 because we know as we get older, our sleep degrades. That's right. And we also know that as we get older, our gut microbiome degrades and the diversity degrades. Yeah. I wonder if there is a link there,
Starting point is 00:14:40 because why do people who get older not sleep as well? It's an interesting question if it's been answered, but maybe it's correlated. So it's not been answered yet. I suspect that we have enough data to do the correlation study that you just described, which is,
Starting point is 00:14:53 are these two things related? For example, if you look across a longitudinal study, and if we, I mean, we haven't been assessing the gut microbiome for probably long enough to have good longitudinal data yet in the gut microbiome for probably long enough to have good longitudinal data yet in the gut microbiome, but we've got plenty of longitudinal data in sleep, meaning we've started off assessing people
Starting point is 00:15:13 in their 30s or their 40s, tracked them over 15, 20 years, and then asked, is the sleep that they've been having across their life predictive of their all-cause mortality, cardiovascular mortality, cancer mortality. And we've got that data. What we now need is to look at gut health
Starting point is 00:15:30 and ask, as that sleep is declining across the lifespan, longitudinally, what happens to the gut? Yeah. I just was listening to Lee Hood's talk for the Human Longevity Institute yesterday. You know, Lee Hood, amazing guy. Yeah, yeah, fantastic, yeah.
Starting point is 00:15:43 Assistant biologist. And he was talking about how pretty soon we'd be able to look at just a few metabolites in your blood to look at the diversity and health of your microbiome. So through a simple blood test, rather than collecting your poop, which isn't really fun for most people.
Starting point is 00:15:55 No, no. Yeah. Of a certain type to really enjoy that type of stuff. Exactly. So, I mean, there's ways we're going to like actually see these patterns and see the biomarkers. And also the gut dysbiosis drives inflammation and it drives activation of an irritable brain.
Starting point is 00:16:13 That's right. You know, I think we used to think that irritable bowel in medical school was what we called the super tentorial problem, which in English means it's all in your head. It's above the part of your brain called the centaurium, which is keep your brain on the top. And it's like, it was a pejorative view that we doctors had, which is if you have irritable bowel, it's because you're just a neurotic person, and it's sort of you're crazy, and that's
Starting point is 00:16:37 why your tummy's upset. And it turns out that the opposite is true, that it's the imbalances in the gut flora that are causing the brain to become irritable. And that that's really what you're talking about here is that if you've got imbalanced flora, that your sleep isn't good. That's right. And that's...
Starting point is 00:16:56 And to me, that's one of the exciting parts of it. Is that it's both treatable and it's a novel... You know, is it a novel sleep aid pathway? I don't know if it's powerful enough to come close to that, it may not be. But I had a patient in NF1, or maybe actually NF2 now, because both people have said this to me, there's probiotic companies making sleep probiotics.
Starting point is 00:17:17 Yeah, I've seen them too. And they said it dramatically increased their deep sleep. And I was like, wow, that's crazy. And I was like, how does that work? I mean, I love to see the data, you know? Yeah, yeah, yeah, yeah, but it's interesting. But even, I'm not trying to be too skeptical, because as scientists and doctors, you and I both know absence of evidence
Starting point is 00:17:35 is not evidence of absence, so don't judge too quick. But right now, I think the jury's out. Yeah, for sure. And I think inflammation also will drive dysfunction of the brain. And I think inflammation also will drive dysfunction of the brain. And most of the brain diseases, and you can argue that sleep is a brain disease, right?
Starting point is 00:17:51 Yeah. I mean, it's the brain not doing what it's supposed to do. Yeah, when you have sleep disruption, yeah. Depression, anxiety, bipolar, schizophrenia, autism, ADD, depression, Parkinson's, Alzheimer's, these are all inflammatory brain diseases. Yeah. So I'm- And Alzheimer's disease,
Starting point is 00:18:07 there's some really fascinating data regarding inflammation and Alzheimer's disease as a causal relationship now. Oh, for sure. For striking. For sure. Rudy Tanzi actually, you know Rudy Tanzi? Yeah.
Starting point is 00:18:20 He presents an amazing set of data which has to do with a certain population that they've studied that have a gene mutation that prevents inflammation. And on autopsy, at death, these people were cognitively perfectly normal. On autopsy, their brains were just filled with amyloid, like the worst end-case, terminal case of Alzheimer's,
Starting point is 00:18:42 but they were perfectly normal cognitively. Right. Which was so striking to me. And it was the inflammation that's really the trigger. Right. And so, and I think we don't yet know what's happening with tau, which is the other tau protein, which is the other sort of culprit there with inflammation. I suspect it may be the same story.
Starting point is 00:18:58 It may be even more powerfully explanatory of cognition. But you know, it all of this just once again teaches us, I think you and I, maybe people listening, that for so long in medicine and science, we took a siloed organ or system-specific approach. I was a cardiologist, I was a neurologist, I was an immunologist. We are an embodied species, brain and body combined.
Starting point is 00:19:26 I'm an everythingologist. Yeah, exactly. And that's what, if your doctor says that, you're with the right doctor. Yeah, yeah. I mean, this is how the body works. It's just common sense, right? We're one integrated ecosystem
Starting point is 00:19:36 and that's what Lee Red Hood has really pioneered, which is the idea of systems medicine and systems biology where we're a big network of networks and everything's talking to everything all the time. And so sleep disruption is sort of the thing that actually, I think, is influenced by so many different factors, like toxins. And I personally had this happen to me. I was the greatest sleeper in the world.
Starting point is 00:19:55 And then I got mercury poisoning. And we know mercury toxicity, one of the symptoms, is insomnia. And I don't know how it works. I don't know how it causes it. But we were talking earlier before the podcast started about mitochondria and how many of the things that we are exposed to in the environment
Starting point is 00:20:10 are mitochondrial toxins. And that it's energy. And the body needs energy to run everything. And I imagine it's critical in sleep regulation as well. Fundamental. Yeah. And during sleep, we have a metabolic reduction. Part of the one of perhaps the restorative functions
Starting point is 00:20:26 of sleep is to have a metabolic downturn to a degree. But I think the other point is there is, you spoke about all of these different, I'm a multi-system doctor. And yes, what we find is that all of those different systems, each by themselves can all independently affect sleep. If you're in inflammation, if you have high blood pressure, if you have, you know, abnormal hormonal profiles,
Starting point is 00:20:53 if you have poor blood sugar, all of these will disrupt your sleep. So it's feed up to the brain, disrupt sleep, but it also is feed down. And I've often thought, and it works both ways for health and ill health, with good sleep versus bad sleep, but it also is feed down. And I've often thought, and it works both ways for health and ill health with good sleep versus bad sleep. If you've gone into one of those, um, fancy music
Starting point is 00:21:12 studios and there's that mixing deck with all of those little dials on it. That makes me so intimidated. And yeah, and I look at it, Oh my goodness. And you can move all of the different dials. They're all of the different systems, but you know that there's that one white dial all the way to the far left. That if you move that up, all of the different dials, they're all of the different systems, but you know that there's that one white dial all the way to the far left,
Starting point is 00:21:27 that if you move that up, all of the other dials go up with it. That to me is sleep. If you're struggling with stress, poor sleep, or low energy, you might be magnesium deficient, like 75% of people. That's why I recommend magnesium breakthrough by bioptimizers. Unlike most magnesium supplements, magnesium breakthrough gives you all seven essential
Starting point is 00:21:49 forms of magnesium for better absorption and real results, deeper sleep, less stress and more energy. I take it every night and I notice the difference. Try it for yourself at bioptimizers.com slash Hymen and use code HYMAN10 for 10% off your order. A lot of times people have restless sleep. they wake up at the middle of the night, they can't go back to sleep and it really affects the quality of their health, their life and everything else. So sleep is critical to our health, to longevity, to our mental health, to
Starting point is 00:22:16 basically every physiological function we have and it really is important to fix it. So let's talk about what you can do to stay asleep and to sleep more deeply. So we know that poor sleep makes us less productive and makes us tired, hard to focus. Basically, having sleep deprivation is basically the equivalent of being drunk. In terms of your performance, I read a study once where they were snipers who were excellent shots.
Starting point is 00:22:42 And if they had eight hours sleep, they were like 100% accurate. If they had seven hours sleep, they were like 100% accurate. If they had seven hours sleep they were like 95% accurate. If they had six hours sleep they were like 70% accurate. And if they were like less than six hours sleep they were basically like 50%. It's like almost a hit and miss. So not good. Even when you're an expert in something you can't function when you're tired.
Starting point is 00:23:02 So next to sort of nutrition exercise and maybe even before it's somewhat argued, sleep may be the fundamental foundation of health and disease prevention and even weight control. So why is it so important? How does sleep dysfunction lead to change as well? There's a very important hormone called cortisol, which is your stress hormone. And it helps when it's imbalanced to go up in the morning to get you energetic and focused and do the things you need to do for the day. And at night it's supposed to go down and you're supposed to calm down and relax. Now a lot of people have an inversion where their cortisol is all in the morning, they can't get out of bed and at night they're tired and wired.
Starting point is 00:23:40 Sound familiar? I bet you've some big experience that I certainly have at different moments in my life. When you get down in bed, you're exhausted, but you can't fall asleep because you're just wired. It's unfamiliar. I bet you've had some big experience that I certainly have at different moments in my life. When you get down in bed, you're exhausted, but you can't fall asleep because you're just wired. That's to do with your adrenal glands. And they're designed to keep things in balance to regulate your weight, to moderate your stress response, to control blood sugar, regulate inflammation, and regulate sleep and wake cycles. So when we're constantly in a state of stress, we're actually often struggling with sleep because of the way in which it affects our sleep. So when you're thinking about it, when your cortisol is high,
Starting point is 00:24:15 you're running from a tiger, you're in danger, you don't wanna be sleeping, you wanna be alert. And that's the problem. So if your cortisol levels are balanced and they're high in the morning and then low at night and your blood sugar stays even, we'll talk about why that's important because fluctuations in blood sugar often will cause midnight or middle of the night awakening but when your cortisol and your body stress response is balanced then your pineal gland produces something called melatonin
Starting point is 00:24:42 that pulses really strong in the afternoon and the evening which gets you ready for sleep and lets your cortisol drop off and then you can feel calm and go to sleep at night and feel sleepy. And if you're healthy and balanced in your circadian rhythms and your cortisol melatonin cycles you'll be fine but if your cortisol is high in the afternoon or high in the evening you might might feel tired and wired. You want to sleep but you can't or you might fall asleep because you're really tired and then you wake up in the middle of the night like between one and four and that happens when you sort of go go go go go do your email, you're working working working and busy and then you go
Starting point is 00:25:19 to bed and you fall asleep because you're exhausted but you end up waking up because your body is still in a stress state, there's still high levels of cortisol. So how does stress affect your sleep-wake cycles? Well, it works in a lot of different ways. Psychological stress can be a big factor, right? Worries about family, work, money, physical stresses, lack of exercise is a stress, believe it or not, too much screen time, junk food, toxic lifestyles, hormonal imbalances, you know, environmental toxins, all these drive increased
Starting point is 00:25:54 inflammation, increased brain inflammation, and also increased cortisol. Because by the way, do you know this, that when you eat sugar or starch, your body responds by jerking up the adrenaline and cortisol levels. So literally eating sugar is a stressful experience to your body, even if you're getting pleasure and you don't think it's stressful and you're meditating while you're eating sugar, you're still gonna have high cortisol and high adrenaline.
Starting point is 00:26:20 So what are the things that are the two most common things that are screwing up your sleep-wake cycles? It's probably blood sugar imbalances and spikes and crashes in blood sugar and chronic stress. So what should you do to optimize nutrition so you can regulate your stress hormones through food and lifestyle? And how do you deal with actually regulating sleep throughout the whole night and get high quality sleep? So first thing is our bodies, whether we like it or not, are biological organisms, and they run in circadian rhythms, and they need to be balanced.
Starting point is 00:26:56 So you have to live in rhythm. Now I experienced the dangers of not being in rhythm when I worked in the emergency room. I would sometimes work seven in the morning till five at night shift. Then I'd work at two in the afternoon till the two in the morning shift. Then I'd work at 11 o'clock at night to a seven in the morning shift. Then I'd work at eight in the morning to an eight in the morning shift, 24 hour shift. I was all over the place and my whole system became dysregulated.
Starting point is 00:27:19 And ultimately it led to chronic fatigue syndrome and a bunch of other stuff. My system just kind of collapsed because I was pushing through all these circadian rhythms which have to be in balance for you to be healthy. And whether we like it or not, we tend to do a lot better from our health perspective if we go to bed at the same time, if we wake at the same time, if we eat at the same time. Our bodies are designed like that. So you want to make sure that you actually don't eat before bed because that's the worst thing you can do but you need to make sure you're having meals
Starting point is 00:27:51 in a regular time space. So don't eat three hours before bed. Don't eat a heavy meal before bed because that guarantee you that'll screw up your sleep. Also carbohydrates, I think if you want to actually eat some starchy things like sweet potatoes or some more starchy foods and you can handle it metabolically, make sure you do it at night because the serotonin levels go up and it helps with sleep when you have your carbohydrates. But still don't eat white flour, sugar, processed, all that processed food. Also not eating enough is stressful.
Starting point is 00:28:21 If your body's not getting enough food, it's also considered a stress. Now you can do time-restricted eating and you can sort of narrow the window in which you eat for longevity purposes and so on. But you also want to make sure you're getting enough food and not actually starving because that will increase cortisol and you'll wake in the middle of the night. Now if you want to lose weight, you can use what I think is probably the most effective treatment I've ever found, which is the 10-day detox diet. It helps people lose 120, 130, 200 pounds. It's like a gastric bypass without the pain of surgery, vomiting, and malnutrition.
Starting point is 00:28:58 Another thing you can do is get stuff out of your head. Write your worries down at night. So get a little piece of paper or journal or maybe in your phone. Write down all your worries, what you have to do, your days should be organized for the next day. Free up your mind so you can actually let go of things and go into a deep restful sleep. Next, you can try a number of supplements and things that I found very helpful.
Starting point is 00:29:21 Magnesium is super important. It's the relaxation mineral. It helps regulate the stress response, helps you regulate cortisol, helps relax your muscles. I recommend two to 400, even more, of magnesium glycinate before bed. Glycine also helps with sleep, so you can use glycine. And you can use that to help relax the nervous system
Starting point is 00:29:40 and your muscles. Next, try some melatonin. Mellow out with a little melatonin. You can use half, up to two to three milligrams of melatonin at night and that can often help you reset your circadian rhythms, particularly with travel. Also ashwagandha is an Ayurvedic herb that can be really powerful for resetting cortisol. I use a product called Cortisol Manager which helps at night to reduce the stress response and improve sleep quality. Also make sure as I said to get in rhythm you know. Well you can sleep at the same time. Try to go to sleep before 10. That's the best sleep you can have is
Starting point is 00:30:15 before midnight believe it or not. So get in bed by 10 try to be asleep shortly thereafter. 11 at the latest. Try to wake up at the same time every day. Also make your bedroom completely sleep supportive. For example, make sure you have eye shades or blackout shades on your windows or eye shades on your eyes. Earplugs if it's noisy. Make sure you really take care of creating
Starting point is 00:30:41 a carefully controlled environment. Next is caffeine. Some is tolerated okay and metabolized and others don't. So I encourage you to sort of maybe stop after breakfast coffee. Don't have coffee throughout the day. That's particularly important. If you're still struggling, I would probably just stop coffee and caffeine altogether. Alcohol definitely screws up sleep.
Starting point is 00:30:59 So if you want to sleep well and you're not sleeping well, quit alcohol. Just get off it. It can interrupt sleep and creates poor sleep quality. Also sunlight is basically great medicine. You know what I mean? Sunlight, I'm going to go to sleep. No, but 20 minutes of sunlight in the morning without sunglasses on, outdoors, not behind a window has a big effect on your circadian rhythm.
Starting point is 00:31:22 So we are photobiomodulating organisms. The light affects us. It regulates our biology. It's important to make sure you have a good 20 minutes of light exposure in the morning. Sleep is a very strange phenomenon. Like we don't even have a definition for what it really is. But with science, we can see, we know when we're sleeping because there's a change in your brain waves. So what's's deep sleep and light sleep and REM sleep and exactly so we go from this a normal waking state right now We're kind of in beta and get into some gamma as well And then we transition to alpha theta and a deep Delta sleep
Starting point is 00:31:57 And so all of those sleep cycles are correlated with different processes hormones release Neurotransmitters in the body, and our key, it's not necessarily how many hours of sleep you get, it's really the quality of those hours, because you can sleep for eight or nine hours and wake up feeling like trash, like a dumpster juice or whatever, and I don't know where that even came from,
Starting point is 00:32:18 but you can feel terrible, because you're not actually getting efficient sleep cycles, and so that's what I focus on is, how can we ensure that we're getting quality sleep? And for a lot of people, they can potentially sleep six hours and sleep better than folks that are getting nine. Yeah, and the truth is we've sleeping about two hours less than we did 100 years ago per night.
Starting point is 00:32:36 And that is interesting stat. And also the quality of sleep is terrible. And tens of millions of Americans have sleep problems. And it's something that we don't really deal with very well in medicine. We say, oh, take Ambien or take Ativan or take Xanax or whatever. And those have serious consequences
Starting point is 00:32:50 and they reduce the quality of your life, they increase mortality, they increase the likelihood of cognitive impairment and cognitive dysfunction, dementia. I mean, these are real issues where people are dependent on these pills. So how do we get from our sleep deprived and disrupted sleep culture,
Starting point is 00:33:05 what's causing it to fixing it? That's such a great question. You know, today more than ever, there's an epidemic for sure with sleep deprivation and we're seeing this show its face in so many different areas. I think the first step is actually understanding the value of sleep.
Starting point is 00:33:24 And so for example, you know, real talk, nobody's waking up in the morning like, you know what? I wanna look terrible today. You know, everybody wants to look good. And if we understood just how much our sleep quality affected our body composition, I think it would start to push that conversation forward. So there was a really cool study I was done.
Starting point is 00:33:44 It's a sleep and weight are connected. Oh my goodness. University of Chicago did a really fascinating study. So they took folks and they put them on a calorie restricted diet, which is what I was taught to do in university setting, which doesn't necessarily work by the way. Exactly.
Starting point is 00:33:58 But they put them on this calorie restricted diet and during one phase of the study, they allow them to get eight and a half hours of sleep. So sufficient sleep. Another study, another phase of the study, they allow them to get eight and a half hours of sleep. So sufficient sleep. Another study, another phase of the study, same people, same exact diet. They're not cutting any more calories. They're not exercising more or less.
Starting point is 00:34:12 And now they sleep deprived them. So then now they're getting five and a half hours of sleep. They take three hours away. At the end of the study, they compiled all the data. And they found that when folks were getting a sufficient amount of sleep, they lost 55% more body fat just from sleeping. And I didn't say weight, they lost actual fat mass.
Starting point is 00:34:30 Not muscle. Which is crazy. I'm not saying you're doing like eight days a week CrossFit, right? You're just sleeping better. And the question for me is immediately like, oh my goodness, how? How is that happening? And so it's during sleep that we release, this is crazy, melatonin, this super glorified sleep hormone,
Starting point is 00:34:52 which it really isn't that, it's kind of a regulator of your circadian rhythms, period. But it actually is a really profound fat burning hormone as well. So the Journal of Pineal Research found that melatonin is able to- That's that of Pineal Research found that melatonin is that gland in your head that releases melatonin it's like a pineal gland
Starting point is 00:35:09 correct which that's not the only place so we'll get back to that in a moment it's like your third eye gland basically. So the pineal gland and it responds to light and you know all the artificial light and the fact it suppresses it it has to have darkness. So. So the Journal of Polynesian Research found that melatonin increases your mobilization of something called brown adipose tissue or brown fat. And this is a type of fat that actually burns fat. That increases your metabolism.
Starting point is 00:35:37 Yes, and the reason it's brown versus the white adipose tissue is kind of the stuff we think about when we're trying to get rid of fat. Brown adipose tissue is brown because it's so dense in mitochondria, right? These kind of energy power plants. I know you've talked about many times on the show,
Starting point is 00:35:50 but it's such a metabolically active tissue. And so if you're not getting adequate sleep, you're not producing that hormone, nor you get your greatest secretion of human growth hormone during sleep. This is the most, it's also known as the youth hormone in a way. It's the repair hormone. Kids have so much HGH. This is why most, it's also known as the youth hormone in a way. It's the repair hormone.
Starting point is 00:36:05 Kids have so much HGH. This is why they have so much energy. It's muscle sparing and also it's a big component of you healing and recovering. And so you're missing out on that. And cortisol, that's another one. So if you're sleep deprived, one of the very first things we see is an increase in your cortisol levels. That's the stress hormone. Exactly, exactly. And cortisol has this interesting ability to literally break down the muscle that you're working so hard to build. It's terrible. Gluconeogenesis, a process called gluconeogenesis,
Starting point is 00:36:33 break down your valuable muscle tissue and turn it into fuel because it's a stressed, hyper alert, cautious, dangerous state your body thinks you're in because you're sleep deprived. And I can go on and on, I'll share one more. I always say stress is bad because when you have a high cortisol, it does everything you don't want, right?
Starting point is 00:36:52 It shrinks your memory center, your brain, causes Alzheimer's, it causes you to lose muscle and gain fat, it causes your sex hormones to get screwy, it has so many horrible effects, and it's not worth getting stressed about stuff. Yeah, oh my goodness. It has so many horrible effects and it's not worth getting stressed about stuff. It doesn't matter. You know like stuff, there's stuff that does matter that you have to worry about but the truth is most of things we react to and stress about are just our beliefs or thoughts. They're not really real.
Starting point is 00:37:17 Yeah that's a and I even focused on that as well because a lot of folks have what we call clinically just a lot of inner chatter. The brain is a very vocal and kind of noisy organ. You know, and so the great thing is a lot of our needs are met, especially if people are listening to this right now. It's like the crazy ant that lives in your head, you know? Right, right. But we have so many things covered in our lives
Starting point is 00:37:44 that our ancestors didn't have to worry about. But the human mind is so expansive so we can manufacture things to worry about. And that worry can push us. And I often tell people, people coming into my clinic that you can overeat your weight fat, you can under exercise your weight fat
Starting point is 00:37:58 or under move your weight fat, you can under sleep your weight fat and you can also overstress your weight fat for sure. It has a huge component for our overall health and our body composition too. But I was gonna share Stanford University. They found that just one night of sleep deprivation has a dramatic effect on suppressing leptin.
Starting point is 00:38:19 And that's that kind of glorified hunger hormone. I mean, I'm sorry, satiety, satiation hormone and ghrelin on the other side has this uptick and that's that hunger hormone. Yeah. Right. So just one night and I'll And it makes you crave a ton of carbs. I wanna ask you this, I was gonna say,
Starting point is 00:38:36 I know you've been up late before. Oh yeah. But I don't know if it's me or if anybody else listening, have you ever been up at like two o'clock in the evening, maybe at a party, maybe just kicking back watching TV, and you're like, you know what, I really want a salad right now. Nope.
Starting point is 00:38:49 No, if that's ever happened, please inform me. I don't get a craving for broccoli. I want salty, sweet, crunchy, like I want. Carbs. Yes, yes, because your brain is literally starving for glucose, just one night of sleep deprivation, we're seeing about a 14% reduction in glucose reaching your brain.
Starting point is 00:39:06 Yeah, I know it's true. I remember working many nights in the emergency room, delivering babies, being up all night, and the next day all you wanna do is eat carbs and sugar. You know, I'd go to McDonald's and get the Apple Turnovers and the French fries in the middle of the night. Oh, the Apple Turnovers. That was the only thing that was open in the hospital.
Starting point is 00:39:20 So between, it was only closed between two in the morning and six in the morning, otherwise it was open 20 hours a day. It was the only thing open in the hospital. Can you believe it? And I would go, you know, be sleep deprived and stay up all night. And I totally craved carbs.
Starting point is 00:39:33 Wow. And you did that work on that food. And now what you're made of now and the work that you're doing is just like exponential. Like you see that. I thought about this the other day. We're putting folks in space on Vending machine consciousness, right astronaut just imagine if we can get people on really healthy real food
Starting point is 00:39:52 Yeah, and what we can create is humanity. It's exciting So it's exciting about your book about sleep is that you you break it down you talk about 21 strategies that are very specific To actually fix your sleep. Yeah. Because I'm sure many people listening, maybe even half or more have sleep issues, whether it's not enough sleep, whether it's disruptive sleep, whether it's poor quality sleep, or the more serious things like sleep apnea,
Starting point is 00:40:14 people often don't know they have it. So can you walk us through some of the key strategies and what really matters? Sure. So I've been really working to press this into public awareness for about five years now. And this was because seeing people in my office coming in and they're struggling with their blood sugar, for example,
Starting point is 00:40:35 and we had about right around 75% success rate with getting folks off the center prills and metformins and all this and working along with their doctors. But. Those are blood sugar and blood pressure pills. Yeah, and here's the thing, that 25% of folks who weren't getting those results, ironically, that would really bother me.
Starting point is 00:40:53 I know you've probably felt the same thing. Oh yeah, yeah. Ironically, kinda keep me up at night. Is that 20%, what are you missing? And so it took about five years in practice, maybe a little longer, before I had the audacity to ask, how was your sleep? And what people would tell me blew my mind.
Starting point is 00:41:08 I couldn't believe they're even sitting there. And so, and this is another thing that we know, is that folks don't really wanna change too much to get the result they want, and I knew that. And so I just dug into the research and I wanted to find clinically proven strategies that people don't have to turn their world upside down. And once I implemented those with the patients
Starting point is 00:41:27 I was working with, it's like the floodgates would come off. The weight would finally come off. Their blood pressure would finally come down. Their symptoms of depression would start to dissolve. And I was just like, this is really something special. I need to tell more people about this. And so eventually it's compiled into these 21 strategies. And for me, again, some of these things
Starting point is 00:41:46 are gonna be a reminder for folks today, but I wanna talk about something that a lot of folks still don't have a big awareness of. And this is the fact that your gut and the health of your microbiome has a huge impact on your sleep quality. So your poop and sleep are connected? What a concept.
Starting point is 00:42:03 In a way. Okay, let's dig into that one. Don't do the two together. No, that's not a good thing. You know, that's called accident city. That's gonna blow people's mind, and even my mind. Tell us how the microbiome in your gut affects your sleep and what you can do about it.
Starting point is 00:42:15 Absolutely. So let's start with the basic component. And I know again, these are gonna be things people have heard about before probably on your show. But let's start with serotonin. Okay. So it's pretty well known. And by the way, there's more serotonin in your gut
Starting point is 00:42:26 than there is in your brain. Exactly, upwards of 80 to 90% of your body's serotonin is actually located in your gut, produced by your enterochromophin cells, by the way. All right, so. Those are special cells in your intestinal lining. Yes. I'm just translating all the big words, see?
Starting point is 00:42:42 I like that, we're like flipping places, because I would do this for you. So here's what's so interesting is that serotonin, we talked about melatonin being important for our sleep and our circadian rhythm. Serotonin is a precursor or a seed to make melatonin. So already right off the bat, your gut environment, these cells in your gut are helping to make this compound
Starting point is 00:43:05 that's related to your sleep quality. And with melatonin, it's what I wanna liken it to, it's like that manual gear shifter for you to go through your sleep cycles properly and to actually get recovered. You need melatonin to be produced. And we'll come back to that. So that's number one, serotonin.
Starting point is 00:43:20 You can't just take melatonin? I'll answer that in a moment. Okay, okay. That's tricky. Okay. So,in? I'll answer that in a moment. Okay, okay. That's tricky. Okay. So, well, I'll just tell you. So I looked around because some of our colleagues would feel that, and this was just a theory,
Starting point is 00:43:33 that if you take supplemental melatonin, it's going to reduce your body's ability to produce it itself. And that's actually, I couldn't find that anywhere. There was no evidence of that. That's not true. What I did find was taking supplemental melatonin, taking too much or too frequently
Starting point is 00:43:48 can down-regulate receptor sites for melatonin. So your body can still produce it, but the receptor sites that actually do something with the melatonin can get down-regulated. So the key is there, but the lock isn't. So we do need to be mindful of that and we can come back and talk about that. But here's the biggest probably aha moment,
Starting point is 00:44:07 hopefully of this episode, is that it's not just serotonin that's producing the gut. And so check this out. And I just came across this. I'm gonna share this with you today. This was in the World Journal of Gastroenterology. Listen to this. They found that there's upwards of 400 times more
Starting point is 00:44:26 melatonin in your gut than in your brain. Because you talked earlier about the pineal gland. That's what I was taught in school. It's produced by pineal gland in the story. This study found that you can actually have a pinealectomy, which is a removal of your pineal gland, which I don't recommend by the way, don't do that. But-
Starting point is 00:44:42 It's like a frontal lobotomy, go there. And you don't actually lose those levels of melatonin that's located in your gut, right? So you have a gut brain and a brain brain. Exactly. And that's something really important to understand too. Your gut is really, it's often referred to as a second brain.
Starting point is 00:44:58 You know, we can call it the enteric nervous system. There's like 30 neurotransmitters just like your brain. It's like a mass of nerve tissue. 60% of your immune system. There's like 30 neurotransmitters just like your brain. It's like a mass of nerve tissue. 60% of your immune system and most of the genes in your body. Vagus nerve as well. That vagus nerve. So UCLA researchers found that the vagus nerve, which we thought was just kind of like the brain communicating more telling the gut what to do. 90% of the communication from those nerve fibers from the vagus nerve to the brain is your belly, your gut telling your brain what to do
Starting point is 00:45:28 in many ways, totally nuts. And the other thing people should know is that when you're stressed, not only is your cortisol high and you lead to more fat accumulation, stores belly fat, but it actually blocks your cell's ability to burn calories. Because the nerves, the vagus nerve help you
Starting point is 00:45:45 metabolize your food which is a relaxation nerve it also has the effect of decreasing absorption of nutrients so not only are you not absorbing but your your metabolism just slows down which is amazing it's just because of the nervous connection between your stress nerves and your and your relaxation nerves and all your gut function. So profound. But this is just getting out of that isolation thinking. This is what I was taught in school as well.
Starting point is 00:46:13 It's like, you've got- Well, that's functional medicine. The body's a system. Yes, everything is interconnected and it's just a beautiful symphony if everything's working well. So Caltech researchers to kind of get to how does this all connect, they discovered that, and this this was just I mean, it's been around for years, but this is more of a recent like okay meta analysis
Starting point is 00:46:31 Now we know that certain bacteria in the gut communicate with cells that produce these sleep-related hormones and neurotransmitters so your gut cascade your microbiome has a huge impact on your sleep quality. And so now the question is, what do we do about it? How do we protect or support our microbiome? And that's one of the things that's gonna help to improve your sleep quality. So let's just go through a couple. The biggest thing, in my opinion,
Starting point is 00:46:57 is avoiding things that mess it up. So one of those would be eating processed foods. So that crazy amount of sugar has a tendency to feed pathogenic opportunistic bacteria. So that's one thing, avoiding haphazard use of antibiotics. They have a place, but we shouldn't be using antibiotics every time you get the sniffles. And that's literally what, when I was a kid,
Starting point is 00:47:21 just give them some antibiotics. We would even, like if my mom had some antibiotics, just totally negligent. Yeah, give them whatever's in the cupboard. Also, pesticides, herbicides, rodenticides. Pretty metals. Yeah, these things, side literally means to kill by the way.
Starting point is 00:47:39 But these have a pretty, because they're meant to kill small things, guess what your microbiome is made of? You know, and so. And how many millions and millions of people are taking acid blockers, which also terribly disrupts your gut microbiome. Yeah, we're looking at that the wrong way as well.
Starting point is 00:47:56 And so just avoiding those things, but also what I want people to do is support their microbiome by, you know, and this should be just Captain Obvious at this point. And me working at a university for so long as a strength and conditioning coach, before I did my clinical work, I work with people from all over the world. And I would ask them about their fermented foods and every culture had something. Yeah. Right.
Starting point is 00:48:16 So whether it was like some kind of kefir or like pickled, whatever. Right. And so making sure that we're getting a, at least, you know, every couple of days, get a serving in of some fermented food or beverage. Got to eat the kimchi. Yeah, I love kimchi. I got a jar in my fridge. I love kimchi. And my mother-in-law makes it for me.
Starting point is 00:48:33 And she's from Kenya. So they had like fermented, a fermented, like kind of similar to kombucha. Like she knew about this like 20 years ago. And I'm like, what is this weird stuff she's growing? In the kitchen, it's freaking me out. She had grass, like first time I came to visit and they were growing grass, you know,
Starting point is 00:48:52 like it was wheatgrass. But I was like, hey, watch your mom got grass in here. She like, did she get it? I didn't know. So anyways. Different kind of grass. I didn't know. But that is a big component here is like shifting gears
Starting point is 00:49:08 and having a more targeted perspective about supporting that gut microbiome. But also, and this is a really cool takeaway for everybody today is making sure we're getting in servings of what I call good sleep nutrients every day. Yeah, what is that? Cause eating for sleep, nobody really talks about that. So what does that look like?
Starting point is 00:49:24 So the first one I'd share, and this one is from the Public Library of Science, and so they found that vitamin C, which we know about vitamin C, we tend to associate it with the immune system, right? It's powerful antioxidant. But they found that folks in this particular study that were deficient in vitamin C
Starting point is 00:49:40 had a tendency towards waking up more frequently. And getting vitamin C levels elevated reversed their symptoms. So that's just one example. Iron is the other one. If you have a little fairer. Iron is another one. Yeah, that's, oh my goodness, that's huge.
Starting point is 00:49:54 And especially more so for women, it tends to be. And another one, this was published in the journal Sleep. All right, this is the big journal. And what they found was calcium. So this goes back to that story that I was told about calcium. It is important for sure, but folks who were deficient in calcium
Starting point is 00:50:15 had more interrupted sleep patterns as well. And so by getting those calcium levels up, but how do we go about that? I'll just pass it over to you rather than drinking like homogenized, glowing and dark, from a mutant cow. What other sources of calcium do we have? Oh my God, when you look at the data on calcium,
Starting point is 00:50:35 it actually isn't as great as we thought for bones. But the best absorability and use is actually from greens, like arugula and greens that we can have, dark green leafy vegetables. Also, there's some great sources like tahini, which is basically ground sesame seeds. Also different things people might like. I like, which is sardines with the bones in them and salmon with the bones in them, like canned salmon. Those are really great to eat because they have a lot of great absorbable calcium.
Starting point is 00:51:00 Exactly. Calcium is kind of like an end product from this like biological transmutation. So bones have a great source of it, but people say, well, you don't, you need, you need milk. I'm like, well, where do you think a cow gets their calcium from and has strong bones? There's a cow bone. They eat grass. It should eat grass anyway. It's this really fascinating process. It's kind of like, like a biological transmutation of sorts where certain things
Starting point is 00:51:24 come together to create bone, right? So like you need silica, you need- Boron. Boron, right? Vitamin K2, yeah. All of these things come together to make this magic happen. So by the way, I wanna give some sources with vitamin C. Obviously we know about citrus, fruits like strawberries,
Starting point is 00:51:41 sweet peppers, but there are these quote super foods as well, like camu camu berry. This might be the highest botanical source of vitamin C, super tart, tangy fruit. It's like an Amazonian thing. Amla berry, acerola cherry, those are super, super high sources of vitamin C. Another one, and this was,
Starting point is 00:52:01 this is the last one I'll share. There's a whole list in Sleeps Smart. So this was a study conducted by University of Oxford found that omega-3s can help folks to get deeper, more restful sleep. So it helps with those, modulating those rhythms, which it makes sense because it has to do with your brain. Your brain has these gates,
Starting point is 00:52:20 you have the blood-brain barrier, but the gate allows in certain VIPs. And it's only like 30 things, right? And one of those is a mega-virus. Although you can have a leaky brain and then you get more trouble. Oh my goodness. You know about the leaky brain issue?
Starting point is 00:52:31 This is like, you're already, you're getting into some territory here. This is super fascinating stuff, right? Leaky gut, leaky brain, who knew? Who knew? It's so exciting. And also there's some research that just came across the brain kind of has its own immune system in a way.
Starting point is 00:52:49 Yeah, it does. It has its own lymphatic system, which is like to clean the brain every night and guess how you do that? Sleeping. Yep. It's 10 times more active. Yeah, I mean we know if you don't sleep
Starting point is 00:52:59 you're at much higher risk of Alzheimer's because you can't clear out the garbage and your brain gets toxic. It's fascinating. That's run by the glymphatic system. So that's because you can't clear out the garbage and your brain gets toxic. It's fascinating. That's run by the glymphatic system. So that's like little shout out to the glial cells that help to run it. The body is just incredible.
Starting point is 00:53:11 So eat plenty of good sleep nutrients every day. Magnesium though? Oh, that was the last one actually. Okay, I was like, that's the one. First one I go to with my patients. This is the big one. I was saving the best for last. I first learned about the benefits of magnesium,
Starting point is 00:53:27 probably from you. And this was again, you've been talking about this for like 15 years. And I was like, holy crap, because it's responsible for so many biochemical processes. I got 300 enzymes and yeah. And so what that means for people, it's just like, so magnesium is responsible for these,
Starting point is 00:53:44 well, now we know like over 325 processes. What that means for people it's just like so magnesium is responsible for these well now we know like over 325 processes what that means is there are 325 things your body can't do or can't do properly when you're deficient on it Yeah, and and it by the way magnesium deficiency affects forty eight percent of Americans and it's caused by stress Yeah chronic magnesium deficiency. It's caused by stress it's caused by coffee, alcohol, and not having enough in our diet, which comes from mostly plant foods, beans and greens, nuts and seeds.
Starting point is 00:54:13 Absolutely, and this is one of the things that we can do something about, but like you said, it's kind of like an anti-stress mineral. And so just the amount of stress that we're exposed, even our environment is stressful. It's different You know, we're in indoors a lot more processed air and we're not getting access to sunlight Like just our reality is more stressful, but then put on top of that our work demands relationship demands You know, how would you know if your magnesium deficient?
Starting point is 00:54:39 You can get a test done, you know, but I really always most the tests are not very inaccurate red cell magnesium is better Yeah, but it's mostly symptomatic and actually the way we really have to diagnose it is called a magnesium load magnesium load test Where you give people a high dose of ivy magnesium and then you collect the urine for 24 hours And if nothing comes out, it means their body sucked it all up and if it all comes out it means they have enough Right, so I think you know magnesium testing is is tricky, so you gotta go by the symptoms. Yeah, exactly, exactly. That's the thing. And what I was gonna say is I always err on the side of
Starting point is 00:55:10 how do you look, feel, and perform, you know? And in my practice, there were only a couple supplements I would recommend. Magnesium was generally, and maybe for 80% of the people that came in, because there's such a tendency for people to be deficient in it. And so, but here's the issue.
Starting point is 00:55:25 So food first, obviously. Anything green is gonna be a good source of magnesium. So just keep that in mind. Kale, collard, mustard greens. But outside of that, supplementation can be tricky because we have this bowel tolerance. Right?
Starting point is 00:55:42 So even if you take a little bit more than your gut can handle at that moment And you might need to really get your magnesium levels up. You're gonna Activate what we call clinically disaster pants, which means the poop potentially pooping in your sleep Yeah, like the whole thing we this goes full accident of milk and magnesium, right? Magnesium citrate is what they give people before they go. They have colonoscopies to clean out their bowels, right? It works so and there's different forms, and some are gonna be better for different people,
Starting point is 00:56:08 but what I, I don't know if you've done this or looked into this, but like topical magnesium. Yeah, you can use topical magnesium. Yeah. That's what I do. Even brought some with me when I travel, you know, keep it in my back, and I love it. I think it's fantastic.
Starting point is 00:56:22 It's important, and people can overlook symptoms that are all caused by magnesium deficiency right? Sleeplessness, insomnia, anxiety, palpitations, muscle cramps, menstrual cramps, seizures, you know, arrhythmias, palpitations, all those things are caused by magnesium deficiency. It's interesting in medicine we don't really think about it but it's used as a quote drug in the worst cases because drugs don't work. For example preterm labor, someone comes in having a baby too early you give them intravenous magnesium. Someone comes in and they're having high blood pressure and seizures and pregnancy they give them intravenous magnesium. People have heart cardiac arrhythmias where their heart is
Starting point is 00:56:59 beating crazy beats in the emergency room and none of the drugs work you give them magnesium. It's pretty interesting and it's something we use all the time in medicine. We don't think about it in this way, but it is probably one of the most powerful things for sleep for people. I wanted to share something exciting with you. My team and I just launched the Hymen Hive, a powerful new wellness community designed to help you put personalized health into action with the tools, support and accountability to make it last. Inside the hive, you'll get monthly live sessions with me, office hours with our resident functional make it last. Inside the Hive, you'll get monthly live sessions with me, office hours with our resident functional nutritionist,
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Starting point is 00:58:02 it. You can find me on all social media channels at dr Mark Hyman, please reach out. I'd love to hear your comments and questions Don't forget to rate review and subscribe to the dr Hyman show wherever you get your podcasts and don't forget to check out my youtube channel at dr Mark Hyman for video versions of this podcast and more. Thank you so much again for tuning in We'll see you next time on the dr Hyman show this podcast is separate from my clinical practice at the Ultra Wellness Center, my
Starting point is 00:58:26 work at Cleveland Clinic, and Function Health where I am Chief Medical Officer. This podcast represents my opinions and my guests' opinions. Neither myself nor the podcast endorses the views or statements of my guests. This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. This podcast is provided with the understanding that it does not constitute medical or other professional advice or services. If you're looking for help in your journey, please seek out a qualified medical practitioner.
Starting point is 00:58:54 And if you're looking for a functional medicine practitioner, visit my clinic, the Ultra Wellness Center at UltraWellnessCenter.com and request to become a patient. It's important to have someone in your corner who is a trained licensed healthcare practitioner and can help you make changes, especially when it comes to your health. This podcast is free as part of my mission to bring practical ways of improving health to the public. So I'd like to express gratitude to sponsors
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