The Dr. Hyman Show - The #1 Thing Stopping You From Losing Belly Fat - How To Lose It Effectively

Episode Date: May 10, 2024

View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal Carrying excess weight around your midsection can be frustrating, especi...ally if you maintain a healthy diet and exercise regularly. Yet, millions of people worldwide struggle with their weight,  It is crucial to understand that belly fat is more than just a layer under your clothes. It is an active endocrine organ that secretes pro-inflammatory cytokines throughout the body, contributing to our risk for chronic diseases. It's important to recognize that this is not a reflection of personal failure. Our modern-day lifestyles are overloaded with stress, environmental toxins, and convenience foods that actively work against us. In today’s episode, we will explore visceral fat (a.k.a. belly fat), the factors that contribute to it, and how to address it using the principles of Functional Medicine effectively. In this episode, I dive into: Understanding belly fat and obesity (2:51)  The role of diet and lifestyle in the accumulation of belly fat (10:48)  The impact of sleep, alcohol, and stress on weight gain (19:14)  What are obesogens, and how do they make us gain weight? (21:44) Health risks associated with visceral fat and belly fat (23:05)  Where does conventional medicine miss the mark? (24:14) Functional medicine's approach to assessing and addressing visceral fat (26:38)  Dietary and lifestyle changes to reduce visceral fat (30:52)  Rupa University is hosting FREE classes and bootcamps for healthcare providers who want to learn more about Functional Medicine testing. Sign up at RupaUniversity.com. Upgrade your cookware, appliances and more with Our Place. Head over to FromOurPlace.com and enter code HYMAN at checkout to receive 10% off site-wide.

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Starting point is 00:00:00 Coming up on this episode of The Doctor's Pharmacy, belly fat is one of the biggest drivers of having heart attacks. So the question then is, what's driving belly fat? Well, two things, excess sugar and refined carbs and ultra processed food and excess calorie consumption. So basically sugar, carbs and processed food and just too many calories.
Starting point is 00:00:19 It seems that every day more and more patients come into my office bringing ever increasing amounts of healthcare information with them. And I love it when this happens because it means people are taking ownership of their health, but it also means I have to stay on the top of my game. So as a healthcare practitioner, how do you make sure that when a patient walks into your office and says, hey, I really want a Dutch Complete or a GI map, that you have the right answers and tools? The answer is Rupert University. They're the number one educational institute for root cause medicine with over 20,000 practitioners a year learning about functional and specialty lab
Starting point is 00:00:48 testing. Not only do they have absolutely free live classes hosted every week, but they bring in industry experts to teach in-depth six-week boot camps on all the most popular functional tests. If you want to level up your knowledge of functional lab testing, make sure to visit RupertUniversity.com. I'm a firm believer that using your kitchen regularly is one of the most important things you can do to be healthy. And it gives you complete control over what food goes in your body. And that's why I cook most of my meals at home. But have you ever thought about whether your cookware itself was healthy? Well, the problem is that so much nonstick cookware contains PFAS. Those are those nasty little chemicals that can permanently damage our health and the environment. They're so bad that the EU, the European Union, is in the middle of banning them.
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Starting point is 00:01:57 Our Place's cookware, appliances, and more. Just go to fromourplace.com and enter my code HYMAN, H-Y-M-A-N, at checkout to receive 10% off sitewide. That's F-R-O-M-O-U-R-P-L-A-C-E.com and use the code HYMAN. Our Place offers a 100-day trial with free shipping and returns. Before we get into today's episode, I'd like to take a minute to remind you of some exciting news. My new cookbook, The Young Forever Cookbook, will be released on Tuesday, June 4th nationwide. In my new cookbook, The Cooking Companion to My Book, Young Forever, you'll find over a hundred mouth-watering anti-inflammatory recipes that are going to help you live a longer, healthier life. You can pre-order The Young Forever Cookbook at youngforevercookbook.com. Just click on the
Starting point is 00:02:39 pre-order button at the top right. I'm so excited to share these recipes with you and so much more. And again, the Young Forever Cookbook comes out on Tuesday, June 4th. Pre-order yours today. Welcome to Doctors Pharmacy. I'm Dr. Mark Hyman, and welcome to our special edition of Health Bites. Now, let me ask you something. Do you carry excess weight around your midsection, even though you feel like you eat healthy? Do you exercise rarely, but your waistline keeps growing? If that sounds like you, know that you're not alone. Millions of people around the world struggle with obesity and maintaining a healthy weight. And the truth is,
Starting point is 00:03:14 it's not your fault. Let me say that again. It's not your fault, despite what the food industry might have you think. Now, our modern day lif stack the odds against us and today's world doesn't really lend itself to a healthy and happy population either. We live in a toxic nutritional landscape. In fact, it's really the opposite. Many of us are sick, unhealthy, and depressed. First, you have to understand that belly fat isn't just there to keep up your pants.
Starting point is 00:03:41 And what we call a dad bod is so much more. Belly fat is an active endocrine organ that secretes hormones and creates whole body inflammation and all the carotid diseases that come with it. So whether or not you've heard of the term visceral adipose tissue or VAT or visceral fat or belly fat, I'm sure you heard of, we're going to discuss it today. And we're going to dive deep into what it is, what contributes to it, and how to get rid of it using the principles of functional medicine. All right, let's get right into it. What is visceral fat? Visceral fat or VAT as opposed to FAT or visceral adipose tissue is your intra-abdominal fat. It's the fat around all your organs, your liver, your pancreas, your intestines, and all the organs in the abdomen, and it's commonly referred to as belly fat, and it's the number one driver of aging. Why? Because
Starting point is 00:04:30 unlike subcutaneous fat, that fat located just underneath your skin that you can pinch with your fingers, visceral fat is not visible on the outside. However, subcutaneous fat sometimes is a good proxy for how much visceral fat you have, but not always. Visceral fat is not just a storage site for excess energy. It's a metabolically active organ that secretes molecules that impact your hormones and your brain chemistry and your immune system and so much more. Visceral fat has been strongly linked to insulin resistance or prediabetes. We've talked about that forever on the podcast. In other words, diabesity and very high levels of inflammation. Now, a lot of hormones are affected by or produced by visceral fat.
Starting point is 00:05:11 Some of them are called adipocytokines. Cytokines are inflammatory messenger molecules that are made by adipocytes, otherwise known as your fat cells. Leptin, often called the satiety hormone because it helps regulate energy balance and inhibits hunger, right? It's the feel-full hormone that's affected. Leptin levels are often directly proportional to the amount of body fat we have. The more visceral fat we have, the more body produces leptin,
Starting point is 00:05:34 which seems like a good thing, right? Because then you're not going to feel hungry, but it's the opposite because you get leptin resistance. So leptin resistance occurs when your leptin levels are consistently high, just like an insulin resistance. So in leptin resistance. So leptin resistance occurs when your leptin levels are consistently high, just like an insulin resistance. So in leptin resistance, the brain doesn't respond to leptin signals effectively, and it leads to continued eating and fat accumulation, especially around the belly, despite adequate or even excess fat stores.
Starting point is 00:05:58 So it's like your body feels like it's starving in the midst of plenty. Another hormone that's important in regulating body fat is something called adiponectin. Now this is a good thing because it enhances the body's ability to break down glucose and has an anti-inflammatory and insulin sensitizing effect. But the bigger your belly fat, the lower your adiponectin levels. So it's kind of not there helping you when you've got extra belly fat. And adiponectin levels go down as your belly fat goes up. High adiponectin levels are also good
Starting point is 00:06:28 and they're associated with a lower risk of type 2 diabetes and heart disease. And lower levels of this important hormone adiponectin are associated with an increased amount of visceral fat and it makes insulin resistance worse, which is a hallmark of metabolic syndrome or prediabetes or diabesity or type 2 diabetes or whatever you want
Starting point is 00:06:45 to call it. It's all the same thing. The next set of hormones that are regulated in fact by your belly fat are probably surprising to you. It's your sex hormones. Yep, your sex hormones. You see, visceral fat, particularly in men, well in women too, but in men it's really acting badly. It contains an enzyme called aromatase and that converts testosterone or the androgens, the male hormones, into estrogens. And that converts testosterone or the androgens, the male hormones, into estrogens. And that results in high estrogen levels for men, which is not good. And it leads to low testosterone levels, which affects fertility. It affects energy, brain function, sexual function, and lots more. It can contribute to erectile dysfunction, loss of lean body mass and muscle, and increased risk for
Starting point is 00:07:23 heart disease. So it's not good. Now in women, and particularly in pre-penipausal women, high levels of belly fat or visceral fat cause the opposite. They cause a high level of androgens or testosterone, which then increases the risk for something called PCOS, which is a common cause of infertility and acne and weight gain and irregular or heavy menstrual bleeding in women. It's really common and it's really annoying and it affects a lot of women. And it's primarily related to this excess belly fat, not for all women, but for most. Now in peri and postmenopausal women,
Starting point is 00:07:51 high levels of visceral fat increase aromatase and estrogen levels. And that leads to the risk for estrogen-related cancers like breast, uterine, and ovarian cancer. So as your body fat goes up, your estrogen production goes up and the risk of estrogen-related cancers goes up. Now, the other thing that's produced by belly fat is something called cytokines. You might have heard the cytokine storm with COVID,
Starting point is 00:08:13 and these are things that are not bad or good. They're basically designed to regulate your immunity and fight infection, and they can be good. But when they're overactive all the time, they just drive this chronic sterile inflammation. And this belly fat that you have, or hopefully you don't have it, is driving an enormous amount of these inflammatory cytokines because the fat cells themselves become cytokine producing factories, particularly something called IL-6 and TNF-alpha. These are extremely triggering for chronic inflammation throughout the body. And essentially it's like a fire in the belly. Think of it that way. It's driving fire everywhere in your body. And this contributes to this sterile, chronic, low-grade inflammation. And that leads to all these other issues. And even things like high
Starting point is 00:08:53 leptin and low adiponectin. Inflammatory cytokines are really the problem. In fact, that's why so many people with obesity had a high risk of COVID, serious infections, and death because they were already pre-inflamed. So high leptin, low adiponectin, and these pro-inflammatory cytokines are a recipe for disaster. It contributes to systemic inflammation, to insulin resistance, which are really critical factors in developing type 2 diabetes and heart disease, even certain cancers, and even dementia. All of it's related to the same thing, which is this pre-diabetes, belly fat, inflammation, insulin resistance. It's all one problem. It also causes a lot of others, right? It causes abnormal cholesterol, really bad types of cholesterol, not the kind of just you get on your regular panel, but ones we check with a special test
Starting point is 00:09:33 looking at lipid particle number and size. And when you have atherogenic dyslipidemia, which is a big medical word for you have high triglycerides, low HDL, small particles, lots of particles, it's caused by the belly fat. Now, when you have high levels of belly fat or visceral fat, it causes high levels of something called free fatty acids. These are the basically fuels from fat in your blood, especially in the presence of insulin resistance. Now, normally insulin inhibits the breakdown of lipids or what we call lipolysis. So insulin, the higher it is, it breaks the ability of the body to burn fat. It basically stops your body from burning fat, which is not a good thing. And now when
Starting point is 00:10:08 insulin resistance is high, when your body's resistant to the effects of insulin, you keep making more and more insulin, you're actually not able to burn the fat. It's almost like the fat gets in the cells, but can't get out. It's like a one-way turnstile at the subway. And this leads to the mobilization and release of triglycerides, which are shuttled to the liver by the portal vein. And that creates, you know, more, more, more, more trouble. And that combined with inflammatory cytokines and other bad cholesterol particles, high triglycerides, small dense LDL, low levels of HDL, all this dramatically increases the risk of developing heart disease. In fact, belly fat is one of the biggest drivers of having heart attacks. So the question then is, what's driving belly fat? Well, two things, excess sugar and refined carbs and ultra-processed food and excess calorie consumption. So basically sugar, carbs, and processed food and
Starting point is 00:10:55 just too many calories. So what are the main sources of these excess calories in the American diet? Well, the main source of all calories and any calorie in the American diet is ultra-processed food. It's basically science projects made by the food industry from deconstructed ingredients that they get from a farm originally as soy, corn, and wheat, but turned into all kinds of molecularly deranged, chemically extruded, colorful food-like substances that don't even meet the definition of food if you look at the definition of food in the dictionary, which is something that supports growth and health
Starting point is 00:11:26 of a living organism, which it doesn't. And what is it? It's refined sugar, it's starch, processed fats. And when we looked at the data, and I'm just gonna share some studies, all the links are gonna be in the show notes. You can dig into it yourself. In a study called the PREDIMED study, a very big trial,
Starting point is 00:11:39 1,500 participants, randomized controlled trial, people 55 to 75 who are overweight or obese, for every 10% of their diet that was ultra-processed food, they had a significantly greater accumulation of belly fat. And even worse, in another study, the Global Bird Industries, 195 countries, they looked at their diet and they found that for every 10% of your diet that's ultra-processed food, your risk of death increases by 14%. And guess what, folks? Our American diet is 60 to 70% ultra-processed food. More than two-thirds of our diet is this junk, which isn't actually food. And it's driving this epidemic of chronic disease, which we're seeing all across
Starting point is 00:12:17 America and increasingly the globe. Here's the other kicker. It's way easier to overeat ultra-processed food. I mean, who binges on a bag of avocados? Bag of potato chips, bag of cookies, no problem, right? These are hedonic foods. They're high in sugar, salt, and fat. They're designed to make you overeat. They're designed to activate the addiction centers in your brain. And this is not an accident, my friends. If you want to read about this, read Salt, Sugar, and Fat by Michael Moss. He talks about the very pernicious way in which the food industry has actively created taste institutes where they hire craving experts to create, quote, the bliss point
Starting point is 00:12:50 of food to create heavy users. I'm not making these terms up. This is literally their own internal corporate terms. Craving experts, taste institutes, bliss point of food, heavy users like addicts. They understand the biology of this and they are after it. And what's even worse, I'm sorry, I'm just getting a little rant tangent here, but they are putting little kids as young as two years old in MRI scanners and showing them images to see which images will most activate their reward center in the brain. How do we addict little kids? This is criminal, my friends. What this does is when you eat ultra processed food, it doesn't actually make feel full, and it then makes you eat more. And the data is really clear. We'll share it in a minute. But when you eat more, obviously you're going to gain weight. There's a landmark trial by an NIH scientist called Kevin Hall and his colleagues published in the journal Cell
Starting point is 00:13:36 Metabolism. And they did a very elegant study. They took 20 healthy weight adults, and they randomly assigned them to eat either an ultra-processed diet or whole foods for two weeks. Now, the meals in each diets were identical in terms of calories, macronutrients, protein, fat, carbs, sugar, sodium, fiber. But on average, the people assigned to eat the ultra-processed food ate 500 calories more a day than the individuals assigned to eat the whole food diet. Think about that. When you are given food to eat, you're going to eat more if it's ultra-processed food. And most of the calorie surplus came from carbs and refined carbs and refined oils, not protein, because you can't overeat protein. I mean, who's going to eat a 20-ounce steak? It's really hard to do,
Starting point is 00:14:12 but you could easily eat a whole bowl of pasta or two or three or four. Now, carbs and fat are high in ultra-processed food, and carbs that we're eating are refined grains, flour, and sugar. I'm not talking about broccoli, which is a carb, or asparagus, which is a carb, or blueberries, which are carbs. Those are all fine. I'm talking about the industrial carbs that we consume. Also, the industrial oils, the refined oils we have, which are ubiquitous in our food supply and add extra calories and oxidative stress. And the other thing is ultra-processed foods are typically low in protein, and so protein makes you feel full. And if you have low protein in the food, it's going to make you want to keep eating until you can find the protein
Starting point is 00:14:45 because it's the only macronutrient we need in gram amounts. Think about that. There's no biological need for carbohydrates. Fatty acids, we have some essential fatty acids, but they're really needed in milligram amounts, right? Whereas protein you need in large, large amounts. It's the only macronutrient that you need. And if you don't get it, you're going to keep looking.
Starting point is 00:15:01 The ultra processed food group in this study also gained significantly more weight than the whole food group, which lost weight over the two-week intervention period. What else is causing us to gain weight and belly fat besides ultra-processed food? Well, all the added sugar. Well, it's coming out, obviously, partly from the ultra-processed food, but also sugar-sweetened beverages. In this country, the average American consumes about 22 teaspoons of added sugar, or about 152 pounds a year. Now, I'm not having that much, my friends, so some of you out there are eating a little bit more. The average kid consumes about 34 teaspoons a day. Think about that. That's a lot of sugar. I mean, you wouldn't put 34 teaspoons in your coffee, would you? But
Starting point is 00:15:37 we get that every day for our kids. So liquid calories and liquid sugar calories are the worst from sodas, fruit juices, sweetened nut milks, sweetened coffees, energy drinks, teas, sports drinks, all this stuff is just poison. Do not drink sugar-sweetened beverages, period. It will dramatically change your life. And sugar-sweetened beverages and sweetened coffees and teas basically contribute to about 40% of the intake of added sugar.
Starting point is 00:16:01 So if you just cut those out, you're going to be doing yourself a big favor. Now, why are liquid sugar calories so bad? Well, they're consumed in isolation from their food matrix, right? So they're fructose and glucose and who knows what else, sometimes there's other sugars. They're just pure sugar and they don't contain fiber, they don't contain protein, and they don't contain fat, which all slow down the absorption. So once they're quickly absorbed, it spikes your blood sugar and your insulin, and high insulin drives excess fuel into your fat cells. Now, what does insulin do?
Starting point is 00:16:27 It basically opens a gate and lets the fuel, sugar and fats, into your fat cells, making them grow and grow, especially belly fat. Insulin makes belly fat. Just remember that. Insulin makes belly fat. It's the fat storage hormone. High insulin leads to more cravings and an increase in hunger because you're getting high insulin, then you get a sugar dip, and then you're going to be in a life-threatening
Starting point is 00:16:46 situation. You think you're dying because you're not getting enough sugar, hyperglycemic. You have more sugar cravings, more carb cravings, and it's a huge problem. This is called the carbohydrate-insulin model of weight gain. There's other theories around weight like energy balance and obesogens and redox models. We've talked about those at length on the podcast, Doctors Pharmacy with Robert Lustig. It's complicated, but basically this is a big, I think probably the number one driver of weight issues, which is refined starches and sugars. And the other thing besides sugar is flour. We eat so much flour and refined
Starting point is 00:17:30 grains. According to the USDA consumption data, the average American consumes about 152 pounds of sugar and 133 pounds of flour per person per year. Now in a cross-sectional analysis, the participants from the Framingham Heart Study, one of the biggest studies ever done, when they had three more servings of whole grains per day they were 10 likely to have belly fat than those who consumed no whole grains now what are whole grains whole grain oats brown rice bulgur things like that wheat germ refined grains were what english muffins bagels muffins biscuits white rice pasta pancakes waffles crackers pizza you get it now the refined grains were positively associated with subcutaneous fat and fat or or visceral adipose tissue. So you both got subcutaneous fat, but also you got the dangerous
Starting point is 00:18:09 belly fat. And that's because refined grains just are high glycemic. In fact, they have a higher glycemic index than sugar. They spike insulin and they promote fat storage. Also, refined grains don't have any fiber, which slows the absorption of sugar. And the fiber, which is present in whole grains, promotes all kinds of good things like incretin hormones. You might've heard of those. Probably don't know what I'm talking about, but you do because it's a GLP-1 hormone or otherwise known as ozempic, which your body makes. And that delays gastric emptying and prevents overeating. So basically fiber is like a natural GLP-1 agonist. And I've had patients that was 40 pounds just taking extra fiber supplements before meals. I'm not safe with the taking ozepic. Also being sedentary, we're an incredibly sedentary society. In a cross-sectional study of the NHANES data,
Starting point is 00:18:48 this is a National Health and Nutrition Examination Survey, which is this big national government study that's going on for decades and decades. They looked at 10,000 adults who are 20 years or older who were inactive and sat more than eight hours a day. They had the highest total and trunk body fat, in other words, belly fat, compared to those who were more active and sitting less than four hours a day. So being physically active for at least 150 minutes a day helped offset the effects. What else causes belly fat?
Starting point is 00:19:13 Not sleeping, lack of quality sleep. Not getting enough sleep is linked to an increased calorie intake the next day. I can tell you that's true. So I don't sleep, I'm craving the carbs, I'm looking for the bagels, I'm looking for the sugar, I get it. And even though I know all this stuff, my brain is hijacked.
Starting point is 00:19:26 And if I don't get enough sleep, I want to eat all the bad stuff. And when you do that, you get higher visceral fat. So if you don't sleep, you're going to get belly fat. A small trial of 12 healthy non-obese adults found that when people were restricted from sleep for 21 days, in other words, they weren't allowed to sleep a full eight hours, they consumed on average 300 more calories than the control group who were sleeping nine hours a night, which sounds like heaven. And the one who didn't sleep also gained significantly more weight. Now, according to the CAT scans, the excess calories consumed were converted into visceral fat. So when they looked at actually imaging studies in this group, they found that
Starting point is 00:20:04 they just converted all those extra calories into belly fat. What else causes belly fat? Alcohol. Now in a population-based study of nearly a thousand Japanese men, those who had higher weekly alcohol consumption, it was strongly associated and significantly associated with higher abdominal vat or visceral adipose tissue. They had a higher waist circumference, a higher waist to hip ratio. We're going to talk about what that is, which are both independent variables and are concerning to me as a doctor because that's what's linked to mortality. Another study showed that men who drank more than three drinks a day, which is a lot of people I think, were 80% more likely to have belly fat than those who didn't drink as much. You've heard of beer belly? Well, that's it. And that is what's going on here. The beer belly is driven by this extra
Starting point is 00:20:45 visceral fat, which then creates more estrogens and more fat. It's just a vicious cycle. But it's probably, you know, alcohol's calorie content, its impact on appetite, fat burning, hormone sleep, insulin sensitivity, a lot of things. And maybe some other factors too. But we definitely know that when you consume a lot of alcohol, it does increase estrogens in the body for sure. And that it makes you gain weight. And it's just a vicious cycle. Now, maybe there's other factors, maybe unhealthy user bias. Maybe those who drank were more likely to smoke or more likely to be sedentary, be unhealthy. So maybe that was part of it. But for sure, it's not just that. What else makes you gain belly fat? Stress. Literally, stress makes you fat. I wrote about this in one
Starting point is 00:21:21 of my first books, Ultra Metabolism. Higher levels of stress are linked to greater belly fat accumulation and also makes it harder to lose fat. In fact, it's really cool. Every single fat cell is innervated by a nerve from your vagus nerve, from your sympathetic nervous system. Your nervous system is literally wired into your fat cells. And when you're stressed, they're listening
Starting point is 00:21:39 and it's danger zone and you don't want to lose fat when you're in danger because you might need it. That's why stress makes you gain weight. It also makes higher cortisol levels, which basically makes you gain weight and have belly fat and diabetes and high blood pressure. And basically in human and animal studies, if you've been exposed to cortisol at a high amount over your lifetime, it definitely leads to more fat deposition and more belly fat. And then you get this vicious cycle because more belly fat leads to more cortisol, secretion, and then poor stress, stressful tasks. And it's just a vicious cycle.
Starting point is 00:22:06 That's a lot of things that cause belly fat. And there's more. Obesogens. What are obesogens? Obesogens are environmental toxins that make you gain weight. And I've written a lot about this in my book. Many of my books, actually, the environmental toxins by many mechanisms are driving obesity through a whole series of things that lead to insulin resistance, that lead to thyroid dysfunction, that affect your metabolism, poison your energy
Starting point is 00:22:28 production and the ability to burn calories. There's a whole series of reasons. But these endocrine disrupting chemicals promote obesity by increasing the number and size of the fat cells. They alter your basal metabolic rate. They affect your gut microbiome. They affect your hormones and your hunger hormones. And there's many of these things out there and they're everywhere. PFAS, which are the forever chemicals, which are like a Teflon and other things, BPA, lining cans, phthalates, plastic bottles, parabens, and skincare, pesticides, glyphosate, they're everywhere. Now, why is visceral fat so problematic? Visceral fat increases with age and it's related to reduced life expectancy and chronic disease. It's just bad news. The bigger
Starting point is 00:23:04 your belly, the shorter your life. The bigger your belly, the smaller your brain. We'll get to that. Now, one of the most predictive metrics that determines your risk of death is the size of your waist, your belly fat. Now, this fat leaks inflammatory cytokines, we talked about those, that drive inflammation throughout your body, and they make insulin resistance worse, and they negatively affect your heart, your brain, your liver, and your gut. And then what happens? Well, you get type 2 diabetes, you get heart disease, you get prediabetes, you get certain cancers like colon, breast, pancreatic, and prostate cancer, and you get fatty liver, which is affecting I think 90 million Americans now. It's so common. PCOS, which is a hormonal condition that affects
Starting point is 00:23:38 women. Autoimmune diseases. Depression is linked to poor metabolic health. In fact, many psychiatrists are now calling depression and mental health as a metabolic disorder of the brain. Even Alzheimer's is called type 3 diabetes. Bigger belly, smaller brain. So just remember that if you want to keep your mind as you get older, you got to shrink your belly. And research shows that people with larger stomachs in their early 40s
Starting point is 00:23:58 have nearly three times the risk of developing dementia than the Alzheimer's when they reach their 70s. And if you're a diabetic, your risk of Alzheimer's is four times the rate of someone who doesn't have Alzheimer's. So where does conventional medicine miss the mark? I mean, everywhere. It doesn't take a proactive approach. A yearly lab testing is kind of so superficial and your results often come back, quote, normal, despite serious underlying metabolic dysfunction. Basically, rely on your weight and your height, which is kind of not very helpful because your BMI, which is the metric we use that looks at your height and weight as a way of regulating your obesity metric, doesn't take
Starting point is 00:24:33 into account muscle mass, doesn't take into account muscle loss. So you often will misdiagnose obesity. Let's say someone who's a bodybuilder will have a BMI that's high and they can actually be not obese and not fat. And someone who's very thin, who's like a BMI that's high and they can actually be not obese and not fat. And someone who's very thin, who's like a 65 year old lady who's looks skinny, could be skinny fat because they look thin on the outside, but have high levels of visceral fat on the inside. It's estimated that much of a third of the population is skinny fat. The problem with BMI is it doesn't look at what's an important metric, which is the waist to hip ratio or your waist circumference. Because if you have a giant
Starting point is 00:25:05 belly, well, that's a bad thing, right? And that's really what we're looking at here. And also, the conventional approach just looks at calories. All calories are the same. It doesn't matter if it's soda. It doesn't matter if it's broccoli. As long as you're not eating more than you're burning, you're fine. And that's just not how it works because calories and food is information. And information regulates your biology in many ways. It affects your microbiome. It affects your immune system. It affects your hormones, your brain chemistry. So it's not just as simple as calories in, calories out. And the energy balance model, you know, has some merit, but it isn't the whole story. And we need to look much deeper than that.
Starting point is 00:25:39 This whole cultural meme of eat less and exercise more is the answer to weight loss. I mean, how's that working out for you all there? Not so good, right? Not so good because it doesn't work because if you worry about what you eat, you don't have to worry about how much you eat because your hormonal signals will correct and you'll actually self-regulate your appetite and you won't be craving like we saw in the ultra processed food study. When you look at just energy balance, it doesn't really address the hormonal impact of food. And doctors really, on the other hand, also can't blame them because they know training and nutrition like zilch, nada, zip. I learned about like rare nutritional deficiency diseases that I've never seen, like rickets and scurvy. So like that was
Starting point is 00:26:13 my nutrition training. And they don't know how or they don't have the time to talk to their patients about nutrition. And sadly, less than 25% of medical schools receive the minimum amount of nutrition training. And we're not talking about what's in the training, just that they get on any training at all, right? And they often advise low-fat diets based on outdated ideas. And then you eat more carbs and you gain more weight and they blame the patient when it doesn't work. It's just kind of a vicious cycle. So conventional medicine doesn't get it right.
Starting point is 00:26:38 So what's a functional medicine approach to assessing and addressing visceral fat? Well, you got to check things. You got to test things. So you have to look at the body with some simple measurements. It's not that hard. You can probably do it at home, right? Right?
Starting point is 00:26:49 You need a tape measure. It's one of the most important medical diagnostic tools. Simply put it around your waist and your belly button at the widest part of your belly button and the widest part of your hips. So in the widest part of your belly button,
Starting point is 00:26:59 that's your waist circumference. It's highly correlated with visceral fat. If it's greater than 40 inches in men or 102 centimeters, you're in trouble. And if it's over 35 inches in women or 88 centimeters, you're in trouble. And when they looked at large study, men with a waist circumference of over 102 had a 225% higher risk of having a heart attack. And if your waist circumference was over 88, as a woman, you had a 275% higher risk of having a heart attack. Another study of European women aged 45 to 79 found that those with the biggest waist had more than double the risk of
Starting point is 00:27:32 developing heart disease after adjusting for all other risk factors. This is like a direct correlation. I would say causation, actually. Every additional waist size increase raised the risk for cardiovascular disease by 10%. Now, the other thing you need to know is your waist to hip ratio. If your waist is bigger than your hips, that's a sign of more belly fat. It should be greater than 0.9 in men. If that's higher than that, you're in trouble. And if it's over 0.8 in women, you're in trouble. And that means belly fat. Now, your body mass index says over 25 is overweight, over 30 is obese, and so forth. But again, it doesn't take into account where the fat is. So it's just one metric and not the most important indicator of those, for example, who are skinny fat. Like I said, you could have a 65 year old woman who's basically got sarcopenia,
Starting point is 00:28:13 lost most of her muscle, has got marble fat, and basically looks skinny, but is actually fat. We call that toe feet or thin on the outside, fat on the inside, or metabolically obese normal weight. On the other hand, a muscular physically fit bodybuilder type may look overweight on a BMI, but he just has large muscles. The next thing you want to do is do the proper lab testing. Visceral fat is located within the body's trunk, making it hard to see with the naked eye. So you kind of have to just look, right? And if you look in the mirror and you got belly fat, pretty good indicator you have high visceral fat below the surface. But if you want to look at those particularly lean on the outside and have high visceral fat or marbling
Starting point is 00:28:48 the skeletal muscle, you need some different kinds of tests. So we're going to get into what those are in a minute. Also, by the way, this is really common in kids. Studies suggest that 5 to 10% of children have fatty liver or NAFLD. Now, this is something we used to see in alcoholics, never in kids. I mean, I remember going to an obesity conference and I saw this hepatic surgeon there and it was a childhood obesity conference. I'm like, what are you doing here? Why is a liver surgeon at a childhood obesity conference? He says, well, Mark, the truth is we're now doing liver transplants in kids as young as 15 years old from liver failure from drinking soda and sugar and processed food. This is terrifying to me. It should be a national emergency. Also lab testing also can be really helpful. Now, in functional medicine, we do a lot of tests that look at your
Starting point is 00:29:28 metabolic health, your lipid health, your hormone health. And I co-founded a company called Function Health so that everyone can have affordable access to the right test to know what's going on in their bodies. Now, you can learn more. You can sign up and bypass the wait list, which is quite large, no pun intended, by going to functionhealth.com forward slash mark. And what should you get tested? Well, you should get your fasting insulin tested, your fasting glucose, your A1C, hemoglobin A1C, your leptin level, adiponectin, cortisol, C-reactive protein, which measures inflammation, a comprehensive lipid panel, not just a regular one you get at checkup with your doctor, but we call lipoprotein fractionation, which looks at the number of
Starting point is 00:30:04 particles. You have small, dense particles and the size of the particles. You also want to check your hormones, right? Testosterone, estrogen, sex hormone binding globulin, because it affects your sex hormones. And you might want to do additional testing like body composition. You can use an in-body scan, which is something many doctor's offices have, a DEXA scan. The most accurate is a CT or full body MRI, but not everybody's going to get that. It's kind of expensive. The DEXA and the other scans help you see the amount of organ fat and the amount of muscle and where it is. So it's really important to do. And I recommend all my patients get a DEXA scan.
Starting point is 00:30:35 Now, many gyms, fitness centers, health centers have an InBody, so you can start there. But you want to go check it out. And you can find out the nearest location near you by going to InBodyUSA.com. So what's the functional medicine approach to get rid of visceral fat? You got to get to the root cause of it. And you know what it is? It's diet, diet, diet. You cannot exercise your way out of visceral fat.
Starting point is 00:30:57 You just can't because food is what's driving most of it. And you have to handle your diet. So the first thing is avoid all the things that make you gain visceral fat, right? Ultra processed food, refined flour, sugars. We talked about all that. Trans fats, added sugar, liquid sugar, all the sugar, sweetened beverages, juices, not your friend. Snacking, we should not be snacking, right? They just contribute to calorie surplus. If you're going to snack, make it high in protein or fiber. I like macadamia nuts. If you're going to eat food, which you're going to have to do, eat the right food. If you eat whole foods that are low in starch and sugar, low glycemic, it definitely helps you lose that belly fat. Now, I don't recommend this for everybody, but ketogenic diets are more effective
Starting point is 00:31:32 than low-fat diets for losing visceral fat when you do them properly. There was one study that took overweight participants with or without insulin resistance and put them on a low-carb, high-fat diet, about 5% carbs, 30% protein, 65% fat, or a low-fat, high-carb diet, about 63% carbs, 13% to 23% protein, and 20% to 25% fat, which isn't actually even that low-fat. They did it for 15 weeks.
Starting point is 00:31:57 The low-fat group restricted calories, right? Because basically, when you eat low-fat diets, you're hungry all the time, and you have to restrict calories, but the high-fat group did not restrict calories. Think about that. The low-carb eat low-fat diets, you're hungry all the time and you have to restrict calories. But the high-fat group did not restrict calories. Think about that. The low-carb, high-fat group, even though they didn't restrict calories, lost twice as much body fat.
Starting point is 00:32:13 They also lost significantly more visceral fat than the low-fat group, about 18% versus 5%. So basically, eating a lower-carb, higher-fat diet worked for weight loss and belly fat loss. Now, the insulin-resistant individuals in the low-carb, high-fat group, people who are basically eating a lower carb higher fat diet worked for weight loss and belly fat loss now the insulin resistant individuals in the low carb high fat group people who are already like pre-diabetic lost significantly more visceral fat than the insulin resistant individuals who were in the low fat group so if you have low fat and you're insulin resistant it's not a good idea
Starting point is 00:32:38 low carb diets promote belly fat loss they do and a controlled feeding trial of 69 healthy overweight men and women they were randomly assigned to a low or high glycemic, low calorie diet for eight weeks after, you know, washout period. And they were provided with all these different foods in both phases. Basically, they were given their food. They knew what they were eating. The low glycemic group, the ones who had the low starch sugar, had 11% less intra-abdominal fat than the high glycemic group at the end of the trial, despite losing the same amount of weight. Now think about that. When you eat low starch and sugar, you lose the belly fat.
Starting point is 00:33:11 Even if you're losing weight everywhere, you're losing it more from your belly. The low glycemic group lost more abdominal and body fat, and the high glycemic group lost more lean muscle mass, which is not what you want to have happen. So the people who had more starch and sugar lost more muscle, which is critical for your metabolism. Also, what else do you want to do? You want to eat protein in every meal
Starting point is 00:33:30 because it makes you feel full, about 30 grams. And people who have higher protein tend to have less visceral fat. It makes you feel full. It increases all the fullness hormones. We call the satiety hormones. You might've heard of one of them, GLP-1, otherwise known as Ozempic, PYY, and CCK,
Starting point is 00:33:44 all of which helps you reduce cravings and hunger. So you want to eat about 0.7 to 1 gram of protein per pound of ideal body weight. I'm about 175 pounds, so about 150 to 170 or so grams of protein for me. Focus on quality, right? Wild-caught small fish, grass-fed, organic, regeneratively raised meats if possible. I love Force of Nature, which is a great source of meats. Pasture-raised chicken and eggs. Eat lots of fiber. Fiber slows the absorption of starch and sugar and also makes you feel full. And eat lots of phytochemicals because they have all kinds of beneficial things that help regulate blood sugar and insulin. So make yourself a plate of about 75% of your plate being veggies. Non-starchy, colorful veggies. All colors. And also eat a lot of green
Starting point is 00:34:23 veggies like chard, spinach, broccoli, kale, cauliflower, dandelion. Well, cauliflower is not green, but anyway, it's part of the broccoli family. Dandelion greens, Brussels sprouts, asparagus, cabbage, bok choy, broccoli rabe. I'm having that tonight. Have it in my fridge. Collard greens and so forth. You can have those in unlimited amounts. Eat some fruit, but eat the lower glycemic fruit like blueberries, cherries, blackberries, raspberries, cranberries. Had some of that in my smoothie this morning. Some stone fruit, apples, pears, all that's fine. Watch out for the tropical fruit. It has a big effect on blood sugar and also fat. Fat is your friend. Fat, you want high quality fat. Avocados, olive oil, nuts, seeds like almonds, walnuts, chia seeds, flax seeds. I wrote a whole book on this called Eat Fat, Get Thin. It works. One guy wrote me back
Starting point is 00:35:04 after doing it. He lost 200 pounds. You can eat grass-fed meats that are fatty, wild caught seafood like sardines, herring, mackerel, anchovies. Maybe you don't like those, but I do. They're fatty and good. What about your lifestyle choices? Well, don't eat out at fast food restaurants and chains. You don't know what you're getting. You don't know what's in the food. There's missed your oils, added sugar. Just not great. Sleep. You want to prioritize sleep. Seven, eight hours a night so you don't get those carb cravings. You also want to deal with stress. Active relaxation, really important. So meditation, yoga, journaling, walking in nature, exercise, you know, really important. Also don't eat when you're stressed. If you take five deep breaths before you sit down to eat, you're going
Starting point is 00:35:41 to change your metabolism. Literally. Say a prayer, maybe grace, take a moment to relax your nervous system, just breathe. It's really important. Exercise obviously is a really important way to reduce visceral fat, but you can't exercise your way out of a bad diet. But you do want to exercise. So at least about 150 minutes a week can help mitigate the effects of being sedentary. So aerobic exercise like walking, jogging, swimming, cycling, do moderate intensity exercise as well like so you can do it over several days basically modern intensity means being able to talk but not sing during the activity about zone two training strength training critical building muscle is key that's your metabolism is body weight exercises resistance bands free weights machines whatever whatever
Starting point is 00:36:19 works for you at least two to three days a week focus on major muscle groups sprint training we call hit training also increases your metabolism it may be the most effective way to reduce visceral fat according to the research, maybe one to three times a week, where basically you go to 89% of your maximum heart rate followed by rest or low intensity training. Time-restricted eating can also be helpful. So try to eat most of your meals within a window where you're giving yourself a 12-hour break overnight or 14-hour break. So you're eating within a 10-hour window or 12-hour window is better than eating all the time and eating when you go to bed and eating when you 12-hour break overnight or 14-hour break so you're eating within a 10-hour window or 12-hour window is better than eating all the time and eating when you go to bed and eating when you wake up.
Starting point is 00:36:48 Definitely will help your metabolism work better. Also, hormesis is great. Hormesis is essentially where you do stuff that doesn't kill you that makes you stronger. And you can actually increase the burning of visceral fat through hormesis and the browning of visceral fat, which is a really cool idea. So the browning of your belly fat means you turn white fat into brown fat. Now, why should we care? Because brown fat is also known to be very metabolically active. It's full of mitochondria, which is what makes it more metabolically active. It has higher metabolic rate and it burns more calories. So how do you activate your brown fat and how do you even turn your white fat into brown fat? Well, cold therapy really works.
Starting point is 00:37:28 Jumping in a cold plunge, cold bath. I was recently in Iceland and I did three minutes in a 35 degree ice bath every day. And holy cow, that was cold. There was even ice cubes in it one day. Of course, I was in a sauna beforehand. But still, very important to do cold therapy. It can be very helpful for you. You don't have to do long.
Starting point is 00:37:42 Just a minute, three minutes. Sauna, very helpful also. Maybe 15, 20 minutes, about 170 degrees. Activates a lot of metabolic pathways that are great for you. Phytochemicals, which are another kind of stress because they're the plant's defense mechanism, can be really helpful in metabolic health.
Starting point is 00:37:58 Green tea is great. Resveratrols and blueberries, cranberries, grapes. Capsaicin and hot peppers. Genestine and diazine, which are non-GMO sources of soy like tofu, tempeh. Lots of spices are great like turmeric, cinnamon, berberine. Also you want to avoid environmental toxins as best you can, like pesticides.
Starting point is 00:38:15 Buy organic when you can. I use the Clean 15 and Dirty Dozen Guide from the Environmental Working Group. Just go to ewg.org. Don't drink from plastic bottles. Get rid of BPA and plastics if you can from your life. Drink from stainless steel or glass containers. Don't heat food in plastic containers. Watch out for your skincare stuff full of phthalates. So you can use the Skin Deep database
Starting point is 00:38:34 from Environmental Working Group to check your products and find ones that aren't full of these nasty compounds. PFAS also is everywhere. It's these forever chemicals. Just make sure you get a high quality water filter for your house. So that brings us to the end of our conversation around visceral fat, which is far more than unwanted weight around your midsection. It's an active endocrine organ. It's secreting cytokines and hormones and neurotransmitters that have a horrible impact on our health that makes us age faster, increase risk for all chronic diseases.
Starting point is 00:39:03 But it's something that you can do something about. It's totally fixable. It's within our control, but it is the single biggest crisis of our time. So I hope this episode helped shine a light on the dangers of visceral fat. And I know that there's many things that you can do that are within your control that you can do to help reduce it. So get on it. Thanks for listening today. If you love this podcast, please share it with your friends and family. Leave a comment on your own best practices on how you upgrade your health and subscribe wherever you get your podcasts. And follow me on all social media channels at Dr. Mark Hyman. And we'll see you next time on The Doctor's Pharmacy. I'm always getting questions about my favorite books, podcasts, gadgets, supplements, recipes, and lots more. And now
Starting point is 00:39:42 you can have access to all of this information by signing up for my free MarksPix newsletter at drhyman.com forward slash MarksPix. I promise I'll only email you once a week on Fridays and I'll never share your email address or send you anything else besides my recommendations. These are the things that have helped me on my health journey and I hope they'll help you too. Again, that's drhyman.com forward slash MarksPix. Thank you again and we'll see you next time on The Doctor's Pharmacy. This podcast is separate from my clinical practice at the Ultra Wellness Center and my work at Cleveland Clinic and Function Health, where I'm the chief medical officer. This podcast represents my opinions and my guests' opinions, and neither myself nor the podcast endorses the views or statements of my guests. This podcast
Starting point is 00:40:21 is for educational purposes only. This podcast is not a substitute for professional care by a doctor or other qualified medical professional. This podcast is provided on the understanding that it does not constitute medical or other professional advice or services. If you're looking for your help in your journey, seek out a qualified medical practitioner. You can come see us at the Ultra Wellness Center
Starting point is 00:40:40 in Lenox, Massachusetts. Just go to ultrawellnesscenter.com. If you're looking for a functional medicine practitioner near you, you can visit ifm.org and search, find a practitioner database. It's important that you have someone in your corner who is trained, who's a licensed healthcare practitioner and can help you make changes, especially when it comes to your health. Keeping this podcast free is part of my mission to bring practical ways of improving health to the general public. In keeping with that theme, I'd like to express gratitude to the sponsors that made today's podcast possible.

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