The Dr. Hyman Show - The Latest Science on Microplastics — And What They’re Doing to Your Body | Dr. Shanna Swan
Episode Date: May 20, 2026We’re surrounded by plastics and environmental chemicals every day, but only recently have scientists begun to understand how deeply they may be affecting human health. On this episode of The Dr. H...yman Show, I sit down with Dr. Shanna Swan to explore what the latest science reveals about plastics, fertility, hormone health, and the everyday habits that may be shaping our biology more than we realize. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We Examine: • Why scientists are increasingly concerned about declining sperm counts, fertility, and hormone health • What microplastics, phthalates, BPA, and PFAS actually do inside your body • Why heating food in plastic can dramatically increase exposure to endocrine-disrupting chemicals • The practical changes that may help you reduce exposure and support long-term health This conversation isn’t about fear, rather it’s about understanding how everyday exposures shape our health and where small, practical changes can make a meaningful difference. If this episode has left you thinking differently about everyday exposure and you want to learn more, here are a few great places to start: • Watch The Plastic Detox • Explore Dr. Swan’s work through the Action Science Initiative • Visit UnplasticYourLife.com for practical ways to reduce exposure at home View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Big Bold Health, Timeline, BON CHARGE, Sulighten and BIOptimizers. Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. Visit timeline.com/drhyman for 20% off a subscription on top of new starting price of $79. Head to boncharge.com/hyman and use code HYMAN for 15% off. Visit sunlighten.com and use code HYMAN to save up to $1600 today! (0:00) Microplastics in the human body and their sources (0:56) Introduction to Dr. Shanna Swan (3:34) The Plastic Detox documentary and endocrine disruptors (5:21) Dr. Swan's research journey and phthalates (6:29) Decline in sperm count and reproductive impacts (8:45) Early research and phthalate syndrome in humans (11:03) Sources and broader impact of endocrine-disrupting chemicals (19:38) Classes of hormone-altering chemicals and health impacts (22:51) Health impacts beyond reproduction (24:20) Personal and clinical experiences with microplastics (27:02) Measuring microplastics and routes of human exposure (29:29) Methods to reduce microplastic exposure (31:14) Biological and regulatory aspects of microplastics (35:02) Plastic Detox movie findings and intervention results (41:16) Chemicals in microplastics and their effects (47:21) Legislation and consumer protection against toxic chemicals (50:54) Diagnostic testing for toxic exposure: importance and costs (53:09) Practical steps to reduce chemical exposures (55:35) Avoiding plastic and toxic exposures in daily life (58:10) Skincare, fragrance, and chemical exposure (1:01:19) Rapid-fire questions on health and environmental practices (1:09:06) Resources for testing and exposure reduction
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Microplastics, which is something that's in the zeitgeist now is a problem that people are
worried about, freaked out about, don't know what to do about.
People have measured them in their blood. They've been measured in placenters. They've been measured in seminal
fluid, they've been measured in breast milk, they're breakdown products, very small breakdown products
of plastic and do harm in two ways. They carry the chemical. The chemical is piggybacked on the little
particle. And then they invade the cells. And that invasion, their presence in the human body,
in the cell, itself causes harm. It's not anything you have any control over, really, because
they're so prevalent in our water and in our air and in everything we eat and smell.
and drink. Where are they coming from?
And the answer is everywhere,
and that's kind of scary.
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Today I'm joined by Dr. Shana Swan
to discuss the invisible threat of microplastics.
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Dr. Swan, thank you so much for coming on the podcast.
I'm excited to talk to you about this topic of endocrine instructors and more specifically
microplastics, which is something that's in the zeitgeist now is a problem that people
are worried about, freaked out about, don't know what to do about.
And you recently were instrumental in a movie through your action science initiative called
the plastic detox, which is how to get plastic out of your lives. And I think we're going to get into
all of that, but I kind of want to just start out by thanking you for your work and thanking you for
highlighting the importance and the reality of these end-of-discrimin-chemicals and how they affect us.
And we're just ch-chatting a little bit before the podcast. And years ago, God, it must have been
close to 30 years ago. I read this book called Our Stolen Future by Theo Colburn. And it was kind of like
a silent spring book. It was this book that kind of really really,
kind of set the stage for how these environmental toxins,
we're not just causing cancer,
but we're having huge endocrine disrupting effects on fertility,
sperm count, hermaphroditism and animals, weird stuff.
What was going on that is so bizarre in affecting a reproductive health across all species,
including humans.
And I think that work is only compounded,
and you've been instrumental in unpacking some of that.
So before we get into the whole world of microplastics,
I'd love for you to share how,
kind of you got into this work, how you first came to understand that these compounds were ubiquitous,
how they were affecting human health, and particularly how they were affecting, you know, human
reproduction, and what kind of led you down that path? Yeah, so I was asked to join a committee of
the National Academy of Sciences who was, the committee was asked to look at the question,
do chemicals in the environment that are hormonally active affect human health? Should we be worried
about that. Kind of the same question we're asking today in some ways. And I joined that committee
as I believe they brought me on as a neutral. They have usually neutrals and people on
either side of the question. And at that point, I didn't even know what an endocrine-destructing
chemical was. So I was definitely neutral, although I had looked at environmental factors that
affected fertility for a long time. I hadn't looked at this question.
of endocrine disrupting chemicals.
So that's how I got into it.
I got into it.
I went to the committee.
The first thing they asked me to do was to look at a study out of Denmark
that claimed that Spurkpound had declined 50% in 50 years.
Yeah?
That was the Carlson paper.
And that paper, when I first looked at it, I thought,
uh, probably not.
Probably not going to hold up under scrutiny.
because it was kind of thin.
You've probably seen it.
It doesn't have a lot of...
Yeah, I remember that study.
So were you impressed?
Quiet?
I'm curious.
I mean, it certainly got my attention.
Also, the changing birth race between male and female offspring was also really fascinating
to me how that number was shifting.
And so that all kind of got my attention.
And this was really around 30 years ago when I...
In 1995 is when you joined the National Academy of Sciences.
And our stolen future came out in 1996.
So I was like, oh, wow, this is a thing.
This is happening, right?
So what I did was, as you probably know, I and my colleagues, I had two colleagues
that worked for about a half a year trying to make that Carlson trend go away.
You know, so we looked at things that might explain it like, are there changes in smoking,
changes in obesity rates, changes in how sperm count was measured and so on and so forth,
and put all these variables into a large model, 60.
one studies, we got, you know, all the data from, put it in a big model, ran the model.
And then the big surprise was that that didn't change anything, not to the first decimal place,
a slope.
And you're a statistician by training.
You got your PhD in statistics.
That's right.
So this is like, you know this stuff.
Yeah.
I could not make it go away.
That's what I was trying to do.
I was trying to make this trend to go away.
I could not do it.
And so I had to take it seriously.
And that's when I kind of dove in to this question of, is sperm count declining?
Why is it declining?
Where is it declining?
And that wasn't specifically focused on any particular chemicals.
But then the next big jump for me was when I was traveling with a chemist friend to Japan, John Brock, and he said, Shana, you should look at phthalates.
So that's kind of another big change in my life.
And I said, John, why should I look at phthalates?
Because I had never heard of them, okay?
Right, right, right.
What a naive question, right?
And so he told me two things.
First of all, he said they were in everyone in the United States,
as far as they could determine at CDC,
because they had the N. Haines study that sampled,
a representative sample of the U.S. population.
and you could see that it was positive.
It was detected in this sample, almost 100%.
And then he said, and this was kind of the thing that got me most interested,
he said that his colleagues in the National Toxicology Program
had shown that when a pregnant rodent rat or mouse was exposed to thallates,
that their male offspring developed atypically.
And what they did was they had a less male typical genital tract.
And we can talk about that some more, I'm sure we will,
but they gave this the name the Thallate Syndrome.
And this was very interesting.
I didn't realize this until much later,
but this is the only environmental chemical
that has a syndrome named after it.
Okay?
There's fetal alcohol, but that's not an environmental chemical.
So this was really kind of, you know, changed the whole field in a way.
Now we, yeah, we started having to look at like, what are these?
And are there others?
And to raise the possibility, you see, that a prenatal exposure to a man-made chemical could change.
the life passage, the lifelong development of an offspring.
Yeah.
Right?
And so...
It's kind of wild.
Yeah, kind of wild.
So that got me into, in a big way, into looking at this because what I then asked was,
is it happening in humans?
And that was kind of the big breakthrough for me.
When I found, we can talk about how I did that if you want,
but I did find the phallets syndrome in humans.
So before you go on, before you go on, what are phallites and where are they found and how are we exposed to them?
Because I think people have heard that term.
Yeah.
They might not know what it is.
Just like you didn't know what it was.
Right, right.
It's likely that people are like, what is that anyway?
Actually, in Europe, in Europe, they're banned.
They're like the little rubber duckies that, you know, babies were playing with the bathtub, chewing on.
They're actually being rubber duckeys here, too.
They are.
They are now they are, but they weren't.
That's right.
So what are they?
So these are chemicals that are added to plastic.
And by the way, they're derived from fossil fuels, which is interesting to keep your...
Petrochemicals.
They have a lot of interesting properties that they lend to the plastic.
So they're put in to give it properties, and the phthalates are put in into the plastic to make it soft and flexible.
and it's a large class of chemicals.
They're fairly diverse.
And they're measurable in the human body pretty easily,
which makes my work much easier because they're water soluble.
And being water soluble, they get into the urine,
and as metabolite, they're metabolized.
And so we measure metabolites of thallides in the urine fairly easily.
Everybody listening can do this.
They can get their body.
burden of thallies by peeing into a container and having it tested.
Yeah.
Yeah.
So that makes it very accessible.
The company that I use is called Million Marker, but there are other companies that do that,
I believe, and certainly the government does it.
So it's now measurable.
Once we know this, we know it's measurable, and we know something about what it does
because of those animal studies.
but let me just add that it does other things besides making plastic soft and flexible.
For example, it helps the absorption through skin barrier or other barriers of chemicals.
And so it's added to hand lotion, and it's also added to pesticides.
Well, this is so interesting because if you're going to increase absorption,
you would like that pesticide to go into the plant, right?
So it's added as so-called an inert ingredient, although it's not inert.
And another important thing it does, it helps retain scent and color.
So it's added to makeup.
So, you know, lipstick and products you put on your skin as well as fragrance.
It's actually in all fragrance products.
And that's a pretty big exposure.
Wow.
Yeah, because it helps.
And everything's sent.
Everything's sent.
Everything, right?
Your laundry detergent.
You name it.
So it's banned in rubber duckeys, but it's in everything else.
And it's still there.
Oh, yeah.
Yeah.
So I just wanted to say about the banning.
There was a lot of discussion about what should be banned or whether they should be banned after our studies and others came out.
And finally, they decided.
that they would ban it in children's toys.
That's the rubber ducky.
But I've always been upset about that
because a pregnant woman,
particularly if she has no kids in the house,
is not handling children's toys.
That's not how she's getting her.
She's put on makeup and lotion.
Right.
And she's eating food that's been stored
in phallic containing containers,
soft plastic containers and so on and so forth.
So she's not being protected by this legislation of 2008.
Consumer Protection Act of 2008 did not protect pregnant women.
And we still don't have good.
Or the rest of us.
Or the rest of us, right, right.
But for me, the pregnant woman is particularly critical, you know, because of the Thali
syndrome because the fetus is, you know, particularly vulnerable, especially in the first
trimester or the first part of the first trimester. And I'm sure we'll talk about that in more
detail. But that's when the pathway for the thallet syndrome is laid down at that time.
Yeah, I think that's important. And I think, you know, the doorway into understanding this for you
was understanding the role of thallates in animal reproductive health and then human health.
But this is just the tip of the iceberg.
Thalates are just one of thousands of petrochemically derived compounds that are in everything, everywhere, all at once.
And what's interesting to me is that, you know, in medicine, we're taught that the dose makes the poison, right?
This is Paracelsus's, you know, famous line.
The dose makes the poison.
You know, have one glass of wine, fine.
If you have two bottles of wine, probably not so fine.
However, in the realm of what we call these xenobiotics, which are foreign compounds that have biological effects, and particularly they have estrogenic effects, they seem to be causing harm at very low levels.
And from my understanding, they're not additive.
So one plus one isn't two.
One plus one might be a thousand.
And there's thousands of these that are in and on and around us and that are affecting us.
So can you kind of unpack how these are, where these all are found, what they are and
how they're synergistically affecting us and the kinds of things we're seeing in the science
over the last 30 years about how they really truly impact all aspects of human health,
not just reproductive health.
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Thalates are a class of several chemicals, which have similar structure and similar effect.
And by the way, the thallates are androgen lowering.
They're anti-androgens, okay?
So they're particularly important for things that affect the male side.
But the females are also, as you know, of course, the females need their testosterone also.
So, and by the way, just a little aside in one of our states,
We asked women about their sexual satisfaction and frequency, and women who had higher levels of thallates had lower satisfaction and lower frequency.
Interesting.
It's lower testosterone.
Yeah, that is through the testosterone.
There are other chemicals that affect other hormonal systems, and a really important one for me, studying environmental health, are the bisphenols.
So I think everyone knows about BPA, and that's one bisphenol, Bisfenal, Bisfenal A.
There are many others.
And they're in the market now at Bisfenil S and Bisfenil F, because there was concern about A.
So the manufacturers said, oh, okay, we'll just swap out A for these lookalike chemicals,
bisphil F and S, and then we can put on our models BPA-free.
but they didn't remove the risk.
Okay, so just a little aside, that's another class.
There's another very large class, which are the PIFAS chemicals, so-called the forever chemicals.
And these are affecting the immune system in important ways.
And this is kind of scary because they're, whoa, they're in so much that we use every day.
They're in any, you know, the Teflon pans.
They're barriers.
I think of them as barrier chemicals.
I lay down a barrier in your frying pan, in your pizza box, in your rain jacket, in your, if you play sports, and your sports clothes.
Your Lulu Lemon Outpice.
Well, I try not to, you know, mention brands.
But, but, um, I'm happy to.
Because what are they doing?
You're putting a barrier between the dirt, you know, and your skin or the rain and your skin.
Or, you know, so they're laying down a protective barrier.
sounds good, but in fact, they're conveying harm because they interfere with your antibody response
to vaccines, for example. You know, they're actually pretty powerful. And there are arguably 80
hormones in the body. I'm not sure. I'm not an endocrinologist, but there's a large number of hormones,
probably more being discovered all the time. But, and so when we talk about a hormone altering
chemical, we're talking about something that can affect very, very many things in the body.
And these are critical because the hormones are signaling agents that transport information
from one gland to another and keep your body running.
So if you're going to mess with those, you're going to mess with everything in the body.
That's pretty overwhelming.
Yeah, yeah.
So it's not just reproductive health.
It's pretty much everything, and they're linked to cancer, they're linked to heart disease,
they're linked to obesity.
They're called obesity.
They're called autogenes.
They cause autoimmune disease.
They're called Obesagens because they cause obesity.
So, you know, it looks like they're affecting cognitive health, things like Parkinson's
diseases, certainly linked to these environmental chemicals.
So depression, mood disorders.
I mean, you go through the spectrum of all chronic illnesses.
In some ways, all of them can be triggered by some levels of environmental toxins.
And what's happened in over the last, you know, 150 years, I mean, when you were born in 1936,
which is amazing, you're going to be 90, probably when this.
podcast comes out, so happy birthday. You know, when you were, when you were born, like,
everything was organic. There was no conventional sort of industrial agriculture. There,
there weren't these chemicals everywhere and everything all the time. And we've done this to
ourselves over the last, you know, 100 plus years. And, you know, now we're in this pickle where
we're finally discovering the science of how these things impact us. And the question is,
how do we go about addressing this? Clearly, it's having a,
fertility, sperm counts, sexual function,
and all these other things that are quite concerning.
But before we get into the set of what to do about it,
I really want to kind of go into this world of microplastics
because it's something that's currently in the zeit guys.
People are talking about, a concerned about it,
want to test for it.
I had my microplastic test, I don't know if it was a good lab or not,
but it was like off the chart.
And I'm like, God, I don't, I cook,
I have only glass containers.
I try not to drink out of plastic bottles.
I mean, I do my best.
And I know what I'm kind of aware.
where I filter my water. I'm like, but it's, it's frightening to see what was going on in my body
and how I might be affected by this. So, and it was sort of a seminal paper that came out in the
New England Journal of Medicine, which talked about microplastics in the atheromas or the plaques
and arteries and how that was linked to increased risk of cardiovascular events. And that was,
that was a pretty compelling bit of data. So can you talk about what are microplastics,
nanoplastics, where are they found? What's the difference between microplastics, plastics, and plasticizers?
and like what's a science about these things in human health?
First of all, when we started studying when John Brock said to be a study,
Thalides, he wasn't thinking about, didn't know about microplastics.
That was not a thing in that.
And that's a relatively new area of work.
But there's a lot of overlap.
And let me just say we didn't know about microplastics,
but we knew about particles harming us.
And you know, as a physician, you know that.
we have asbestos.
Asbestos were particles that went into the lungs and caused asbestosis,
and they also caused chemical harm.
So they're similar.
And, you know, silicon also, silicosis.
So it's not that the phenomena of particles, caring, chemicals, and themselves being harmful.
We know this, but we didn't know it about endocrine-destructing chemicals until recently.
So they're breakdown products of very small breakdown products of plastic,
and that do harm in two ways.
At least, whether we may find more, but they carry the chemical.
So the chemicals piggybacked on the little particle.
and then they invade the cells.
And that invasion, their presence in the human body, in the cell,
itself causes harm that is different than the chemical harm, right?
So that's, you know, microparticles 101 or something.
The other thing to know about them, I think, really importantly,
is that measuring them is extremely difficult and expensive.
And you were able to get measured, I don't know what tissue you measure, but blood.
Blood, blood, yeah, yeah.
So people have measured them in their blood.
They've been measured in placentas.
They've been measured in seminal fluid.
They've been measured in breast milk.
There have been pretty much any fluid that's gone through the body.
A body that's been contaminated by plastic will pick up these little particles.
But the measurement of these will also reflect the
particles in the surrounding environment in which they are measured. So if they're measured, if they're
to collect them in an autopsy, you collect them in a place where, you know, in a hospital where
women are giving birth, you're going to get lots and lots of micro articles from the environment.
And this makes it very difficult a challenge to measure these without contamination.
Because they're in the air is what you're saying.
They're in the instruments that are used to collect the sample from, you know, the whatever, placenta.
And so this is a big challenge to the field.
And it also makes it very expensive.
So just it's very easy, I told you, for you to get your urinary metabolites of chemicals measured by sending in your urine.
It is not easy to get your microplastics measured.
It's a much harder process.
Yeah.
and more expensive.
Where do we find these things?
Where are we getting the most exposures?
That's a great question.
Everybody wants, yeah, where are they coming from?
And the answer is everywhere, and that's kind of scary.
But I would say, you know, think about how can things get in the body, right?
You can take them in through your mouth as ingestion.
So food, drink, very important, perhaps the most important.
I can't be sure.
Then we get them through inhalation.
We breathe them in, so in our air.
And then we get them through our skin.
And that's the, through our absorption.
And there's another route which is not very common, not studied very much,
which is if you enter the skin, say, you get a shot or you get blood drawn,
that will introduce some as well.
Getting your blood drawn, just having a needle in your arm?
I haven't seen a study on that, but I've seen that
written up that that is possible. Yeah, because you're breaking the barrier. All of these are breaking
barriers in a way. You know, they're, yeah. So it's another, what you think about, how do things
get in the body? Those are all that people have mentioned that. Yeah. So, but the thing to remember is
it's not anything you have any control over, really, because they're so prevalent in our water and in our
air and in everything we eat and smell and drink. And, you know, that it's very hard to think
about how we could defend ourselves against them. I mean, I would suggest taking a lot of care
with your water because that is a very common source of exposure. In my house, we actually
distill our water, which sounds as complicated, but it's not hard.
It's not expensive.
It's free, actually.
Once you buy the machine,
make sure you buy the thing plastic-free.
Okay.
And then there's filtering,
and you have to worry about plastic in the filters
and changing the filters and so on.
And there's reverse osmosis, R.O., which is, you know,
all of these things are technical.
They take machines.
They take, you know, effort and allow for possible
additional contamination, I would say.
You have to be careful.
that. But water is really important. And bottle water is not great. Just not great. Not great. So filtering your
water or distill water if you can, right? And does reverse osmosis filter actually work for removing
microplastics? Well, I can't say about my, it works for keeping out exposure. Whether it keeps out all
microplastics, I can't say. I don't know. Well, before we get into kind of like the ways of sort of reducing
exposure. So I think there are ways, and I think it's important to think about those as best you can.
I want to go back to the sort of biological impacts of these things. And what do we know now in
26 about what these microplastics are doing to human health? But I have to say, I'm not
distinguishing the harms from the plasticizers and from the microplastics. Okay. There are,
there are, you see them as a continuum of harm. Not so much a continuum.
is inseparable in a way because if you're going to be getting the plastic pieces in your body,
you're going to have the hitchhikers there too, right?
The chemicals that are riding along with them, you can't keep them out.
You can't have the microplastic without the hitchhikers.
And so, I mean, I've done lots of studies on phallets,
and I've been studying the thallite urinary metabolites.
But undoubtedly, all of those people that we studied also had microplastics,
which we did not study.
So it's very hard to separate them.
They're kind of a, yeah, you can have to take them together.
So in that whole category, like, what are the human harms?
Like, what are the things that people should know that they might be causing
or that the data suggests that they could be causing?
The outcomes or the explosion?
Yeah, like, yeah, like, what do they do?
I mean, we talked about reproductive health.
Okay.
Pirm count, fertility, you know, changing in genitals, all kinds of weird stuff.
But, you know, what else is it doing to human health?
Well, first of all, I have to say I'm a reproductive epidemiologist where I live, if you will, is in the reproductive system.
And so that's what I know best.
I also read a lot, so as you do and other people do.
So I'm not sure that my expertise is, I'm not the right person to talk about obesity.
You should talk to the author of Obesagens or, you know, I haven't studied those specifically.
You know, the relationship to cancer.
A lot has been written on that Parkinson's.
You know, there are experts in each of these areas, and I would be reluctant.
I would prefer to talk about reproduction because that's what I know.
Okay, okay.
But also saying that, yes, the harms are widespread and probably in every system in the body.
Yeah, I agree.
And I think from my perspective, looking at this more as a doctor from the high level,
like looking at all the different things that it can affect,
it's clear that the underlying drivers is inflammation, oxidative stress,
immune dysregulation, endocrine disruption.
And it kind of also like this Trojan horse, as you mentioned,
for all the other chemicals that come into our bodies.
Cardiovascular health, obesity, diabetes, autoimmune diseases.
So we're seeing a rise of all these things.
And I think it's not the only reason,
but it's clearly a major reason that hasn't been looked at.
And I think that from my perspective, like,
people are thinking, okay, well, what do I do?
Like, how do I find out if I have them?
How do I test for it?
What can I do to protect myself?
Am I just going to be at the mercy of this?
And what needs to happen also in a regulatory level?
So maybe you can kind of talk about what the diagnostic sort of framework is around this.
Is it worth trying to find out what your levels are and then follow on a protocol and then retest?
Or is it just sort of should we just be focusing on reducing our exposures?
Help us kind of think through this.
Because people are listening and are probably like freaking out.
And I'm like, yeah, what do I do?
You know?
One thing I would say is watch the plastic detox, the most of the most of the most of the most of,
movie because there's a it's on Netflix right it's on Netflix movie now it came out in March and
it's very widely watched scene shown and um that's just a kind of an introduction and I think it's
it will give people hope because what happens in can I just say briefly what happens in the
yes please okay I'll just tell you what
This is when we conducted an intervention where we changed things in people's lives in order to change their health.
The things we changed was exposures to these chemicals we've been talking about.
And what we hoped to change in their lives was their reproductive health.
So to do that, we enrolled, and this is very small, is a very small pilot, okay?
We enrolled six couples, one of whom dropped out for personal reasons.
So very small.
We enrolled them at the beginning of a three-month intervention.
And then we got information about that.
We got a lot of information.
We got a Seaman sample using a at-home collection kit by fellow.
Meat Fellow is the company.
Worked very well.
We also got their urine using Millian Marker.
And then we asked them lots and lots of questions.
And Millie Marker has a team that's trained to ask people about their exposures and to inform them about what the risks of these exposures are.
So it's an educational component, too, the educational component and the testing component.
In their serum, sorry, in their urine, we got the levels of the metabolize.
So we knew what their exposure was when they started.
And we repeated that halfway through, which was six weeks, and then we repeated it after 12 weeks.
which was the end of the intervention.
So the picture is pretty clear.
You start out, you know what's in their body,
you tell them how to reduce it.
They try, they reduce it,
and then we get their levels at the end.
As far as their health goes,
we get their sperm, motility, morphometry, count, concentration,
all these good things at the beginning,
at the middle, at the end,
and then we see who gets pregnant.
Now, who were these people?
These were people who had been trying for more than a year to get pregnant, and they had no obvious causes of their infertility.
So, idiopathic infertility, and they had to be willing to do this and be willing to be filmed, which is a pretty big bar, and wanting to do this.
But if you're listening, you don't need this intervention, you can do your own intervention, which is really interesting.
And several people I've talked to, you know, hosts of shows and reporters are doing this now.
You could do it if you want.
You know, it's very easy to get a kit, send your urine in, have a tested, try to lower your exposure following the tips in the film.
Deplastic Your Life.com will give you a lot of tips.
I'll give you tips.
And then try that for three months.
And why three months?
Well, it's because it takes 70 days to make a sperm.
So we are approximately, you know, giving a little window there.
And, of course, the exposure to both the man and the woman matters.
So, you know, and then you see what happens.
You see have your levels gone down, has your sperm count gone up?
And then if you add, which we hope to do, serum testing, home serum testing is more difficult than home urine testing.
Yeah, but we are adding that and hoping to get hormone levels as well.
So that's kind of the, it's not rocket science.
It's pretty simple.
And what did you find?
Did you see after three months of doing kind of a plastic detox that people's numbers improved?
Absolutely, absolutely.
And their sperm function improved.
Several to nondetect from of quite high levels.
And that's shown in the film.
And we also published a paper containing a scientific paper in a pure review journal with these data.
And so their levels went down.
And the main health impacts related to the sperm function, motility, morphology, did that change?
Yes. Yes. There are semen parameters.
That's really hopeful.
Yes. I'm excited. I'm thrilled, actually, to have this, for the small sample, having this stronger result.
And then we have several pregnancies as well. And three of the five.
And were these in couples that were struggling to get pregnant?
These were absolutely couples that had tried for more than a year, some as much as 10 years to get pregnant.
And yeah, it's quite encouraging, actually, because it was not hard.
Now, this was a particularly intense intervention in the sense that they talked to Millian Marker once a week.
I went to their homes twice, even though they were spread around the whole country because I wanted to see their homes and meet them.
talk to them one-on-one. And, you know, it was so gratifying to get to know them and see,
see them go through this journey. It was thrilling to them, and for me, actually, to know that we
can do this. Everybody can do this. These were not like special, we chosen people. You know,
they raised up their hand. They said, we'll do this. We're infertile and we'll try. And they did.
That's amazing. And a million markers, a consumer environment,
Exposure Testing Company that looks at endocrine disrupting chemicals.
And it uses urine.
It can take plastics and personal care products.
And they're looking at things like bisphenols, like BPA, BPS, BPS, BPF.
These are, you know, BPA may be reduced in certain products, but they replace it with
alternatives that are just as bad or maybe worse, who knows.
And it looks at Thallate, metabolized parabins, which are in a lot of skin care creams,
sunblock oxybenzone, which is actually a lot of sunblocks.
So people are using all these things that things.
they help to help themselves, but they're actually potentially harming themselves.
And so can you talk a little bit about some of these, these chemicals like bisphenol A, Bisfenial A, BPS, BPF,
and some of these compounds that are part of this whole microplastic family?
Well, we've talked a little bit about phthalates and the other sort of big elephant in the room,
if you will, for me is because of my focus on reproduction, is the bisphenols.
And the bisphenols, so I think of bisphenols and phthalates is kind of evil twins.
One of them, the phthalates, makes plastic soft and flexible, and it lowers testosterone.
And the other one makes plastic hard, firm, hard, and raises estrogen.
So they kind of, no.
And so we're, I talk quite a bit about the phthalates, but the bifinals are very, very, very,
prevalent. And every time you go to the store and get a receipt, you know, would you like a receipt?
I say, no thanks, and you shouldn't be touching that either. Because I make a pest of myself,
because it's, I just say, send it electronically. Why would you test it? Because when you touch that,
we've done a study with shows they've touched that, particularly if you have hand cream on,
you're getting a lot of bisphenols into your body. And every cashier gets.
a lot. So all those credit card receipts, you don't touch the receipts. The ATM receipts, the
gas station receipts, right? Right. I mean, half them sent electronically. So, and then
bisphenol lines a lot of things. And I think what everyone here listening would do well to pay
attention to is that it lines tin cans. It lines all your tin cans. Unless there's a specific effort by the
company to say they are not using bisphenol in their linings, and you can look for that,
usually on the package, read that. Because it's a, you know, they have to make that effort
and pay for that, you know, do this in a different way. And that's, you know, something to call attention
to. So choose, try to choose chin cans, which are not lined with bisphenol of any kind, A, B, F, whatever,
alphabet, soup. You know, you put in there anything that starts with bisphenol, B, G.
But does that mean you can't have things in cans?
You can, but you need to look for companies that package their food in cans that are not lined with bisphenol.
There are alternatives, but again, I don't mention brands, but you can look at for that on the package.
You can go to Environmental Working Group, for example, and look at how they rate these things.
There are other companies like Clearia and so on that you can go to check out.
about Cleario is an app.
You can use it to scan a bar, you know,
on the thing you're buying, you scan that barcode
and you can see what's in it.
And including in the pack.
And it's called Clear?
Clear, yeah.
C-L-E-A-R-Y-A.
Yeah, it's an app.
That's helpful.
Put that in the show notes.
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You know, there was, there was interesting,
there was legislation introduced by Dan Feinstein in 2009 called the Ban Poisonous
Adavs Acts, which meant to really limit and phase out BPA and food containers,
beverage containers, can linings and other FDA kind of regulated food contact materials,
but it was defeated because of the industry's massive investment in fighting it and lobbying against
it.
Where are we now with legislation around this?
Where are we in terms of having consumer protection against these toxic chemicals?
Not very far in this country.
I want to mention two things.
One is we know how to regulate products because the FDA does it and they do it well.
They've done it for a long time.
And they did it in response.
I'm sure you know, but your listeners won't know, a response to two very dangerous chemicals in drugs.
One of them was thalidomide that caused children.
children to be born without arms and legs. And one was D.E.S. diethylstylvestrol, which caused cancer in the
children born to women who took it during pregnancy. These are historic. They're old, but they're
really impactful because they changed the process of the FDA. FDA responded immediately to the
DES information and took DES off the market within six months of the publication of
Herb's paper showing that causes the cancer.
So that was responsive.
It was quick.
And they kept on.
And so we know that government can respond quickly.
It can regulate well.
But in this case, it's not doing it largely due to the pressure of the industries that
are involved.
And ultimately...
And it's not just one drug.
It's like, it's the entire chemical industry.
It's not just like one molecule that we're trying to ban.
It's a whole class of things that are used in everything that we consume and use every day.
It's quite huge.
And I think, you know, is there kind of any kind of current legislation on the books in Congress
or in state legislatures that are trying to address this?
Yes.
Let me just say first, I would say that are the best, you know, most successful has been the EU.
with REACH is a program that was put in place by the EU.
The REACH legislation.
Yeah, REACH legislation.
And it has the really important caveat,
which is if you want to bring in a new product and put it in commerce,
you can't do that until it's tested for safety first.
We don't have that.
We don't have that.
We have that for drugs, but we don't have it for other products in our daily lives.
So that's really one of the major things that has to change.
And there is a TOSCA is under revision now, and that will, depending how that goes, that could help.
But it's a very difficult uphill battle, and there are wonderful groups working on this without very much funding, of course, and, you know, fighting very big, big giants of industry.
it's a very slow and difficult process.
I mean, yeah, we all in America bought the line,
Better Living Through Chemistry.
And, you know, I remember being,
you might remember this,
but I was in New York City,
lived in Queens in 1965 during the World's Fair.
And, you know, there was such a big celebration of chemicals.
DuPont had a whole little, you know, dance of routine
and song and dance, literally song and dance
about better living through chemistry.
And we were all so naive in that point.
And I think Rachel Carson
had sort of brought up some of these issues around pesticides and herbicides. But in terms of the
rest of us, it wasn't a thing. You know, it really needs to be, I think, legislation or even litigation
that helps to sort of move its industry out of this because it's only getting worse. And I'm seeing
it in my practice as a doctor, the effect of these. And I actually measure these things. I look at urine.
I look at blood. I look at like body burdens of toxins. Look at cell membrane levels of these things.
Great. And it's quite staggering how much of a problem is when you start to look.
Let's talk about, you know, the testing.
Is it worth people doing the testing?
Is it something they should think about doing and then reducing their exposures and then retesting?
Is that a worthwhile endeavor for people who want to, like, find out where they're at?
It costs money, you know, several hundred dollars.
I don't remember the cost right now to do the whole program.
And that's one thing I should point out that this is a problem that affects people of lower SES more than higher SES.
because they can afford to be tested,
they can afford cleaner products,
which are always more expensive.
They can afford to shop in organic stores.
We haven't talked about pesticides,
but those are also endocrine disrupting.
And they can't afford the time
if they have, you know, working two jobs, three kids.
I mean, who's going to take the time to check out the labels
and, you know, worry about what they're putting on there?
It takes time.
It takes energy, takes time.
money. So, you know, there's this, this is not an equal opportunity hazard for everybody, right?
But yes, I think if you can afford it, and if this will help you change your behavior,
if you're going to go into it and say, well, I just want to know, but I don't want to do anything
about it, then don't waste your time. I mean, why do that? If you want to learn what's in your
body and then commit to go on and make changes in your life. You can. You can, but you have to make
the effort and you have to put in, you know, you have to do it and you have to want to do it. And then
you can do it. So let's talk about, let's say, you know, with or without diagnostic testing,
which I think is an interesting thing, but we can all assume we're basically poison, so we should
just reduce our exposures. You mentioned a few things, like, you know, distilling water, filtering your water,
you talked about the exposures in air,
should have air filters.
I have air filters in my house,
in my bedroom,
and in the place I spend most of my time.
I try not to buy things in plastic,
but it's almost impossible.
You know, like,
how do people go about really reducing their exposures in their home,
in their skincare products,
in the environment that they're in,
and their food?
And how do we think about creating a systematic approach
to reducing exposures?
Because I think that's all,
we can really do at this point. And then, you know, the second following question that we can talk
about in a minute is, is there a way to get rid of this stuff? Like, besides just reduce your exposure,
can you detoxify from it? So why don't we start out with like, how do we reduce our exposures?
So I would say, watch the plastic detox. You get a good idea.
Watch the plastic detox. Okay, that's on my watch list. Okay.
Make a commitment to do this. Actually, what you're doing, each little thing is not going to be that
important, but having a commitment to reduce your exposure in your life and in your family's life
matters, because it takes an effort. You're going to have to take an effort to do this, make an
effort to do this. And I would say I would start with your food. I think food and drink is probably
the easiest and the most important, perhaps, target. And so that starts in the store.
When I was doing the movie, I went around with Cecilia, who was a 12-year-old daughter of one of the
couples. And I was really fun doing this with her, pointing out where the plastic was. And then
looking at how we could avoid it in the store. You know, so looking, you can, you know, get bulk instead
of wrapped production of flour and spices and so on and so forth. And then even, you know, in their
vegetables, some places have vegetables laid out, not wrapped. You can pick a, like several near
me because I live in San Francisco, but you can pick out a head of lettuce and pick out
whatever you're buying. And what I did with Cecilia, I said, let's see what this costs.
So we looked at the cost of the unwrapped and the wrapped, and guess what? The wrapped costs more.
We did it with fish. We did it with other things. So I would say right there, when you're buying the
product, try to buy it not wrapped in plastic. And if you're doing jars, do a glass,
jar rather than a plastic jar and so on and so forth.
So have your eyes open in the store when you're shopping.
Okay.
Then when you bring it home, don't put it in plastic containers because you're just undoing
that good work you just did.
Okay.
And yeah, so put it in a glass container.
You can put it in ceramic.
I save all my glass jars and reuse them and, you know, why not?
And then worry about it when you're cooking.
You know, you don't, we haven't talked about Phaust very much, but I think everyone
knows that Teflon is something to be avoided and black plastic and so on. So think about
what your food is touching on the way from your shopping bag to your stomach. You know, try to keep
plastic out of the picture as much. So like cast iron, same and steel pots. Yeah.
Cast iron is great. It's cheap. And it's a little heavy. I would say the drawback. But yes,
we have many. Good for strength training. I use it for strength training.
double double benefit right and and let me just say here it's kind of trite by now but do not microwave food in plastic
never never never because that's you know what happens is that the the plasticizers which are added
to the plastic are not tightly bound to that matrix and so you heat it the particles get active
they hop out of the plastic, they help into your food, they get into your body.
So don't do that.
Yeah.
Avoid that if you can.
That's a no-no.
Don't microwave and plastic.
Don't store your food in plastic.
I mean, that's a problem with take out a delivery, right?
Because it's all in plastic, really bad plastic containers.
I don't know how, I don't know how to get at that because a lot of the restaurants that are sending stuff out can't afford, you know, high touch,
containers, so you know, they're going to do what's cheap and quick, and then we get that
exposure that way. And the food is put into the containers when it's warm, so it's going to
absorb more of the, yeah. So that is a problem. And taking out from restaurants is also.
Yeah, same problem. Warm food, bad containers. Yeah. No, no. Okay, so we've got, you know,
filter your water, maybe air filters in your house.
When you shop, don't buy stuff brought in plastic, buying glass if you can.
Don't cook with cookware that's got coatings on it that is nonstick.
That could be Teflon.
I don't know if all nonstick is bad.
It's ceramic, maybe probably not bad.
And that's more of nonstick.
There are options, but be smart about it.
And don't definitely cook anything in the microwave and plastic.
Watch out for your skin care products, right?
I think this is really important.
That's the next level.
Yeah, the Environmental Working Group has a great website,
at uh,
eWG.org and they have a,
an app called Skin Deep.
I'm on the board of the environmental working group.
And they,
and they have a really good resources.
You can actually see what's in it.
So, you know, you might not know,
oxybenzone is actually a toxic plastic
that's in almost sunscreens or parabenas in most
skin care products.
So it's, you know,
unfortunately often are more expensive and they're more
challenging to get.
But, but, but I think
if you're doing something every day to your body,
like it's putting stuff on it,
your skin, basically,
What I say to people is if you wouldn't eat it, you shouldn't put it on your skin.
Because it goes through your skin.
It goes through your skin.
You're absorbing it.
I mean, we know in medicine, we deliver all kinds of medicines through the skin.
We have estrogen patches.
We have nitroglycerin, cream, and paste.
We put on people that come in the emergency room with a heart attack because it works so fast.
It gets absorbed right in the skin.
We know this is possible.
So I think those are really important, simple things you can do.
And what else would you suggest that people might think about besides,
those things that we just talked about.
Fragrance.
I would ask people to think about fragrance.
Again, in our studies, we asked women what they used.
These were pregnant women that we were interviewing.
We asked them what they used in the last 24 hours,
and then we asked, was it fragranced?
And when women reported use of fragrance products,
their levels of several chemicals were higher,
particularly the thallites in their bodies.
And so this is not just perfume.
It's also your laundry detergent is fragranced.
Candles are fragranced.
You know, plug-ins in the wall, things you hang in your car, there's a little pine cone.
Yeah, don't do that.
If you can smell it, and maybe even if you like it, you like the smell of it, don't use it.
And that's one of the things that was hardest for participants in the film, by the way.
But there are some natural.
fragrances, right? There's essential oils that people use. So there are things that are okay
in terms of fragrance. Beeswax is great. If you like the smell of beeswax, that's a really nice smell.
Yeah. And there are, there are brands like that I wonder what you think of these that are like
quote organic or more natural brands that like, for example, laundry detergent. There's a bunch of
them. There's Ekover. There's seventh generation. Are those okay if they're fragrance or are those
also problematic? I don't know. I don't know specifically that. But,
But I mean, you know what would be great.
If you weren't sure, if you had the time to ask them, manufacturers,
if they got a lot of questions from people saying,
what is the fragrance in here and is it safe?
And, you know, that kind of question would really, I think,
make a difference pile up if enough people did that.
So if you don't know, I would ask.
All right.
Well, this has been such a fascinating conversation.
I'd like to ask you a set of rapid-fire questions.
Are you up for that?
Sure.
Okay, this one's obvious. You're turning 90 this month. Like, what's your longevity tips? You're sharp, you're smart, you look beautiful. Like, I don't get it. What are you doing? And how do I subscribe? Thank you. I would say be interested in what you do and exercise. Watch what you put in your body and have friends. Friends. I have a wonderful husband. I have wonderful family.
So that's great. I'm really lucky.
I don't know. And jeans. I couldn't control my jeans, but I'm sure they matter.
Well, I think those are all really important. Simple but obvious tips that actually make a difference.
So it's not any secret sauce. It's just the foundations.
Okay, what's the number one thing in terms of all these exposures that people can do?
Like, if you had to pick one thing, what would it be?
Food.
Food. So watch your exposures in food. Okay.
And then you kind of see these cans and say BPA-free,
and it gives us aura of being safe.
Is it safe?
Are they safe?
No, not necessarily.
Probably not.
Probably if they took the trouble to put BBA-free on the label,
they've already put in an alternative like BPA-F and BPS.
That's the problem.
It's like they add other stuff that sounds better, but it's not.
What's the biggest myth about plastics that people believe?
I think that it's recyclable.
That it's recyclable.
Okay, see more.
Well.
We all put our plastic in the recycle box.
Me too.
Me too.
But very small percent of that is actually recycled.
And it's dumped in faraway places that we don't have to worry about and does harm there to the landscape and to the people who are going through it and handling it.
Don't just don't assume that once you start away, you don't have to care about it anymore.
You do have to care about it.
it's not going to disappear.
I think that's important.
A friend of mine started a company called Hero Technology
is developing mushrooms,
different strains of mycelium that actually can digest
and break down mushrooms in landfills,
and they're starting with diapers,
but it's kind of a cool idea.
So what's, you mentioned food,
but what's that one other thing in your home
that people could immediately remove
that would make a difference?
I would say after food, it would be your water,
cleaning up your water,
because there's so much exposures for water.
And then third would be air.
filtering, you know, using a HEPA filter would be good.
So there are things you can do.
Water, air, food, I think those are important.
What's the first?
Heating in plastic or storing in plastic?
Oh, heating in plastic.
No question.
Heating and plastic.
That was clearly the answer.
What's the biggest mistake people make in their kitchen?
I think the biggest mistake is probably storing in plastic because so much is stored in
plastic.
It's so hard.
I have plastic in my kitchen.
I have true confessions.
I don't, I'm not.
my kitchen is not plastic-free completely.
And so that's, it's just really hard.
And it's nonstop, you know, it's coming in when you do takeout.
And it's coming in when you shop and it comes in.
You know, so, you know, it's just hard to think of getting ahead of it.
What do most people do every day they're not aware of that increases their exposures?
Well, we didn't mention clothing.
But, yeah, that's something that, you know, we're just coming to,
belatedly, I would say, awareness of the chemicals, and there are many, many plastics in fibers
and dyes and in our clothing. And it's everywhere, you know, it's on our beds, it's on our
sofas, it's, you know, on our bodies. And it's particularly concerning if you use
clothing that has barriers like attendance, flight attendants, firefighters,
sportswear, children's school uniforms.
PIFAS is the class of chemical I'm talking about.
That's added to all of these.
And it's invisible to us.
So stick with natural fibers, natural fibers, wool, cotton, silk, linen, right?
Right, when you can, yes.
What's worse?
A plastic straw or plastic fork?
Oh, boy.
I don't know. I think you'd probably use that plastic fork more.
And I don't know how they compare in terms of exposure. I don't know.
If you were the environmental czar for America and the world, what would be the policy you would put in place to make things different?
I would solve two million dollar questions.
Moonshot questions. One is how do we make plastics out of safer products rather than fossil.
fields. So we know that there are plastics made of plants. There's potato-based plastics. Right now,
they're kind of niche items. They're expensive. But I think money should be put into that.
We should then solve the problem of how to get rid of the plastics once we made them.
And on the policy front, it's actually investing in those things.
One more, just to add to that, we need to be clear about what it means for something to be safe.
Because we need to say, say for home, at what age, for what systems, and so on.
Testing for safety is very difficult because it's easy to say.
It should be tested for safety before it's put out there.
But think of all the tests you have to do.
You know, you test all these systems in the body and so on.
So that's very difficult.
It's all a hard problem.
And by the way, it shouldn't be consumers' problems.
It should be governance problem.
No.
And manufacturers, manufacturers.
I agree.
And we didn't really kind of dive into this, but you kind of hinted at it.
In Europe, they follow something called the precautionary principle, which is something's
guilty until proven innocent.
In America, it's innocent until proven guilty.
So we introduce all these toxic chemicals.
We don't make the manufacturers prove they're safe.
We let them be in the marketplace.
We let people be exposed.
We let people get sick.
And then maybe 10, 20, 40, 50, 100 years later, we go, oh, wait, we have a problem.
And, you know, and I think that's not a good framework.
for policy. It should be prove it, not you're given a hall pass and like, let's see what happens.
And I think that's really important. A last question is, what's the most surprising thing you've learned in
your long and varied career? Wow. I know. That's a hard one, right?
I would say, because I am an optimist, I learned that we can make a difference by our actions,
that we can clean up our act and that really people want to.
And so I want to help make that happen.
Thank you. That's amazing. Okay. People can find out more about you by going your website,
which is...
Go to shana swan.com.
You've got unplasticyourlife.com, right? Unplasticurelife.com.
That's not mine. That's the film. Or additional help, I would suggest you,
if you want to test your sperm, you go to meet fellow if you want.
to test your urine, you go to a million marker. And there are other companies coming out all the
time. So this isn't going to be the only ones. But I think the question is, do you want to know?
Do you want to know what's in your body? Do you want to, men don't ever know their sperm cow, my way.
They just don't. So if you want to know about what's going on in your body and in your home,
didn't dive in. Don't be afraid. And, you know, do it.
We actually did a podcast on, you know, sperm as a biomarker for health. You know, I think that's
important.
People don't understand that.
So this is amazing.
Thank you for your work.
I hope you get to go for another 90 years.
And I look forward to your next chapter and what you're going to help us understand about this very frightening world.
But hopefully with some optimism and how we can protect ourselves and how we can push our governments to do the right thing.
So thanks so much for your work and for being such a light in this whole dark space.
Thanks for having me so much.
I really enjoyed talking to you.
and, you know, together we can make a change.
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