The Dr. Hyman Show - The Nutrient Blueprint for a Longer, Healthier Life

Episode Date: September 1, 2025

Nutrients are far more than supplements on a shelf—they are life-sustaining molecules that determine how well the body ages and resists disease. For years, their importance was overlooked because ma...ny studies were poorly designed, failing to consider existing nutrient levels or how vitamins and minerals work together. Strong evidence now shows multivitamins can slow brain aging, omega-3s can extend life expectancy, and shortages of vitamin D, magnesium, and B12 are widespread drivers of inflammation and chronic illness. Knowing and addressing individual deficiencies is critical, as these nutrients power billions of chemical reactions every second and are foundational to vitality and longevity. In this episode, I discuss, along with Dr. Rhonda Patrick and Steve Martocci, why nutrients are essential for a healthy body and how to choose the highest quality supplements. Dr. Rhonda Patrick is a scientist and health educator recognized for her leadership in aging and disease prevention. As the founder of FoundMyFitness, she provides evidence-based insights to a global audience through her website and podcast. On YouTube, she engages millions in in-depth discussions on evidence-based strategies for well-being. Dr. Patrick’s focus areas include genetic influences in dietary response, micronutrients, sleep, non-pharmacological approaches to mental well-being, and the surprising and paradoxical benefits of biological stressors such as exercise, heat, cold exposure, and plant phytochemicals. As an associate scientist and board member at the Fatty Acid Research Institute, she advances understanding of omega-3 fatty acids in aging and health. Her research has been published in high-impact journals like Nature Cell Biology, Experimental Gerontology, and FASEB. Steve Martocci is the co-founder and CEO of Suppco, a smart supplement tracking platform helping people take the right supplements with confidence. After years of struggling with his health and hitting 300 pounds, Steve turned to functional medicine and supplements to reclaim his well-being. That personal transformation—and the confusion he faced along the way—inspired him to build Suppco. Suppco helps users track what they’re taking, avoid unnecessary or low-quality products, and personalize their supplement routine with tools like brand TrustScores, protocol guides, and stack analysis. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here: The Nutrient Gaps That Could Be Aging You Faster My Favorite Supplements for Optimal Health & Longevity How to Choose the Right Supplements (and Avoid the Wrong Ones)

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Starting point is 00:00:00 Coming up on this episode of the Dr. Hyman Show, smokers and non-smokers and their omega-3 index. What Bill and his associates and colleagues found was that smokers with a high level of omega-3, so they had a high omega-3 index of 8%. They had the same mortality as non-smokers with a low omega-3 index. Magnesium doesn't get the spotlight like vitamin D or omega-3s, but it should. It helps regulate mood, hormones, energy, sleep, and even blood sugar, and yet most of us are either deficient or barely scraping by thanks to stress, caffeine, processed food, and even depleted soil. That's where magnesium breakthrough from bioptimizers
Starting point is 00:00:42 comes in. Unlike typical supplements that only use one form, this delivers seven forms of magnesium to support key systems in the body like your brain, muscles, digestion, heart, and stress response all in one capsule. You get support for sleep, mood, focus, and energy without the harsh laxative side effects that come from using the wrong form. Whether you're dealing with occasional tension, hormonal shifts, or just feel off, magnesium breakthrough helps fill in the gap fast. Go to buyoptimizers.com slash hymen to get 10% off today. Your body will feel the difference in just a few days. Before we jump into today's episode, I want to share a few ways you can go deeper on your health journey. While I wish I could work with everyone one-on-one, there just isn't enough time in the day,
Starting point is 00:01:24 so I've built several tools to help you take control of your health. If you're a little bit of your health, looking for guidance education and community check out my private membership the hymen hive for live q&As exclusive content and direct connection for real-time lab testing and personalized insights into your biology visit function health you can also explore my curated doctor trusted supplements and health products at dr hymen.com and if you prefer to listen without any breaks don't forget you can enjoy every episode of this podcast add free with hymen plus just open apple podcasts and tap try free to start your seven day free trial i think it's important to know What are the foundational things that are going to protect you long-term, you know, for pennies a day that could actually save your life?
Starting point is 00:02:04 Well, I want to start out with the multivitamins and vitamins don't do anything in their expensive urine, which you also mentioned earlier. Because this is a pet peeve of mine, I guess. I mean, no. And I'll tell you, I'll tell you. About Ray, it was funny that you, I just got introvers, like, sorry, I go to these medical conferences. And I'm like, I ask, okay. doctors, you know, how many of you recommend supplements to your patients? And, like, a few hands will go up, you know? How many of you personally take supplements? I'm like, almost everybody's
Starting point is 00:02:36 hand goes up. Oh, really? Yeah, it's very funny. It's a great question. Yeah. So there's no evidence, but I take it. But I take. Here's a big flaw with a lot of those studies that are cited by journals. Yeah. Great journals, like JAMA, for example. They're poorly designed. They're poorly designed. So, you know. Designed like drugs, I guess. Exactly. Exactly. Exactly. So the problem is when you have a drug trial, randomized control trials are the gold standard, right? You have a drug and then you have a placebo. But the thing is, is that with a drug, everybody has zero levels of that drug in the start of trial. That's right. So you don't have to measure
Starting point is 00:03:16 anything, right? Because there's nothing to measure until you take the drug. There's no, like pre-OZempic level, although actually the way of Ozempic is true, you have a GLP1. Yeah, bad example. But like stats. So, you know, but when you, when you're doing a... You don't have a normal blood level of lipitor, right? Right, exactly. When you're doing a study on vitamin D or omega-3 or fill-in-the-blank vitamin mineral, everybody has varying levels of these micronutrients in their body.
Starting point is 00:03:43 And so you have to measure things. You have to measure things at the start of the trial. You might have someone that's already got sufficient levels of vitamin D. They may have 50 nanograms per milliliter level vitamin D. And so you give them a vitamin D's. supplement, and it's not going to do anything because they're already sufficient, right? Or the converse is they're so deficient, and you give them a supplement that's 400 IUs or 800 IUs, which doesn't raise their blood levels hardly at all, that it doesn't really do anything.
Starting point is 00:04:11 And so you won't- Doses wrong. You don't measure who's sufficient. Like, yeah, I mean, like, if you don't have a headache and aspirin doesn't do anything, right? So it's like if you, if your levels are great of omega-3s and you add omega-3s, you won't see a change in your health, right? Exactly. So that's the fundamental flaw of clinical trials in nutrition, that right there, is that the MDs that are running these trials are running them like their drug trials. And they're not. You have to measure things. With that said, there have been some well done trials. And in fact, I just been trying to.
Starting point is 00:04:44 The other thing, the other flaw is that they will use a single dose of a nutrient that usually works as a team. like, and they can actually make things worse, like the beta-carotene trials and smokers show that it can cause cancer, but oxidative stress is managed by a whole team of nutrients. So like I would say, you could be, you know, you know, Michael Jordan, but if you're playing one against five on a basketball team, you're going to lose every time, right, even if he's the best player in the world. So you need a team of, of these nutrients, particularly in terms of the oxidative stress cascade, to actually modulate free radicals.
Starting point is 00:05:21 and if you give a high dose of one nutrient, you're going to kind of screw up the whole chain. Yeah, that is possible, not to mention the fact that smokers, I mean, if you give beta-carotene to non-smokers, it doesn't cause cancer. But smokers are doing so much oxidative damage and they're getting DNA damage that a high dose of something like beta-carotene,
Starting point is 00:05:40 which can be an antioxidant, may then allow, you know, some of that. It's basically, it's allowing some of the cells that would otherwise die from the oxidative stress, you know, not to die, right? And so, yeah, it's a very complicated thing when you're doing things like that. But, you know, I think like it was about 10 years ago, there was a huge study in the annals of internal medicine. And it was called enough is enough. Vitamins and mineral supplements, not only don't do anything that may be harmful. Yeah. I think that was, you remember that study? Yeah. It was about 10 years ago.
Starting point is 00:06:09 Yeah. And, you know, I was, I just dug in and it was a meta-analysis and I went and looked at all those studies. And I found that all these flaws, again, coming down. You look at the actual studies that they made their conclusions from. So they do a review. and they go, we're going to look at all these studies and we're going to make a summary and that's called a meta-analysis. And then from that, you didn't just take their conclusions. You actually went and looked at the data itself
Starting point is 00:06:31 from the original studies. Exactly. Yeah. And I put out a video about it like years and years ago. And all these flaws that we just talked about were there. And here we are 10 years later and the Cosmos trials was just published, right? So this is another meta-analysis of a couple randomized controlled trials where older adults were given
Starting point is 00:06:49 a multivitamin. They had about 20 or so essential vitamins, essential minerals, omega-3 fatty acids, vitamin D, right, magnesium. This was all present in this multivitamin, and they were given it for two years. Yeah. What the study found, these are randomized controlled trials, placebo-controlled, right? The multivitamin actually did improve brain aging. So they were less, people taking the multivitamin mineral supplement,
Starting point is 00:07:17 were less likely to experience cognitive dysfunction, memory loss. And in fact, they experienced a improvement in their brain aging that was equivalent to reversing two years of brain aging. Wow. Wow. Yeah. Brand mice control trial. Here we are, 10 years later.
Starting point is 00:07:33 Yeah. And there's many, many other studies that show the value of nutrients in many, many different conditions, right? Exactly. Yeah. You know, I think that it comes down to, yes, you should try to get your micronutrients from diet. it. However, taking, you know, a multibitamin supplement, taking vitamin D, taking omega-3s,
Starting point is 00:07:51 like these are insurance, right? This is insurance to make sure you're getting your optimum levels. So you asked about deficiencies and what are some of the common ones. Well, omega-3, okay, so about 80% of the world's population and 90% of the U.S. population does not meet the requirements for omega-3 fatty acids. Yeah. That's a lot. Which is basically what your body's made of, you know, the cell membranes, your brain, You know, a nervous tissue runs regulatory inflammation. I mean, it's critical to everything. Exactly.
Starting point is 00:08:21 And there's been a lot of work by Dr. Bill Harris. So I'm an associate professor at the fatty acid research institute with Bill Harris. And so I'm involved in a lot of research on omega-3. And he's published just an array of studies that are quite convincing. So looking at the omega-3 index, so this is the omega-3 levels in red blood cells, which is sort of like a long-term marker for omega-3 because they take about whatever. What does the index actually measure? It measures the EPA and DHA levels along with a bunch of other fatty acids if you're interested in that.
Starting point is 00:08:55 But it's really the EPA and DHA level in the red blood cell membrane, which gives you the index and you want a certain number. Exactly. So he's published studies using like the Framingham cohort. So these are large cohort studies with a lot of people. and he's looked at the omega-3 index and correlated with all-cause mortality, so dying from a variety of different causes. And what he's found is that people that have what is defined as a high omega-3 index, so this would be 8% or more, have a five-year increased life expectancy
Starting point is 00:09:28 compared to people that have a 4% omega-3 index, which is low. And actually, the average omega-3 index of the U.S. population is about 5%, pretty close to that 4%. Yeah, yeah. Well, that's why we actually measure that. in the function health labs. Yeah. It's great to see when we see that. Five-year increased life expectancy.
Starting point is 00:09:45 If you think about Japan, Japan, they eat a lot of seafood in Japan, their omega-3 index on average is like 10%. So they're above the high, the 8%. Yeah, yeah. The mercury levels are probably also very high. What's funny, it's funny that you should say that, Mark, there's been studies like in pregnant women. Yeah.
Starting point is 00:10:03 You probably remember this, that decades ago, women were advised to stop eating fish because of the high mercury. And that actually had a detrimental sort of. effect because omega-3 fatty acids, as you mentioned, they're so important for the brain, very important for neurodevelopment. And there have now been a whole host of studies that have come out showing that omega-3 fatty acids actually protect from any potential mercury toxicity in the developing fetus. And in fact, there's been studies looking at children that were born to mothers that had a high level of omega-3 and high mercury. Those children had scored higher on intelligence tests,
Starting point is 00:10:39 So IQ scores, even if so high mercury was actually biomarking intelligence. It wasn't actually the mercury. It was high omega-3. That's crazy. But yes, you get the- Although in Japan they eat a lot of seaweed, which I seeweed is a key later for heavy metals. Oh, is it? So is green tea, by the way.
Starting point is 00:10:56 I think garlic. Garlic, the beta-mercaptains and garlic as well. But back to the omega-3 and this study I was talking about from Bill Harris is so interesting because he also, this is a huge cohort of people, the frame. There's people that have all sorts of lifestyles, including smoking. And so he did a sub-analysis looking at smokers and non-smokers and their omega-3 index. And what Bill and his associates and colleagues found was that smokers with a high level of omega-3, so they had a high omega-3 index of 8%.
Starting point is 00:11:29 They had the same mortality as non-smokers with a low omega-3 index. Okay, everybody, this does not mean you can smoke and take your official pills. I don't get any ideas. Or if you're not getting enough omega-3, it's like smoking, right? I mean, if you look at it's another one at it's got, right? If you look at the graph of this, I mean, it's incredible. The overlay is perfect. Yeah, perfect.
Starting point is 00:11:51 Fascinating. So having a low omega-3 index had the same mortality risk as smoking. Okay, so we're talking about 90% of the American population is in that category. Yes, yes. And, you know, there's also been a whole host of randomized control trials looking at at omega-3s being cardioprotective, right? So they're very important for cardiovascular health, triglycerides. Yeah, there's actually prescription omega-3s, which you can pay much, much more than you go get an basic omega-3 for lowering triglycerides as a therapies. Right, yeah. And you mentioned
Starting point is 00:12:25 inflammation, you know, so this is another thing. They do, they play a major role in lowering inflammation. And so that's a driver of aging in many ways, brain aging, you know, cardiovascular aging. So omega-3s are, I would say, one of the most profound lifestyle factors that can play a role in negating inflammation aside from exercise. Yeah, and they're just, they're so, like the word I use is pleomorphic, but it's a big medical word. But essentially it means a dozen million things, right? It's not just one thing. It's great for your skin, for your hair, for your nails, for your brain health, for preventing dementia, cardiovascular disease, cancer. I mean, it's, it regulates inflammation.
Starting point is 00:13:06 So these are nutrients that do so many things in the body, then they work differently than drugs. And they're essential, they're called essential because they are essential. Right. And, you know, one of the challenges is that we're looking for that, you know, quick fix and we're trying to diagnose a real disease that's directly connected to that particular problem. So I'm sure if you're familiar with Robert Heaney, who was a vitamin D researcher,
Starting point is 00:13:33 and he wrote this beautiful paper years ago called Long Latency to, deficiency diseases. And the basic thesis was that in the short term, if you're a nutrient deficient at a severe level, like we used to see, you know, in the 1900s, if your vitamin D is super low, you'll get rickets. Or if you don't have enough vitamin C and you're a sailor, you get scurvy, right? Or if you don't have enough, eat too much white rice and white flour, which they started you're doing it this turn of century, you get Barry, Berry, Berry, and Pallagra and all these horrible B vitamin deficiencies. The thesis you had essentially is that you can correct those vitamin deficiencies in the short term to fix those deficiency diseases like if you're low and folate
Starting point is 00:14:14 in the short term, it'll cause anemia, a form of anemia, which is big cells called megablastic anemia. But in the long run, it can cause cancer and heart disease and dementia. And same thing with vitamin D. You know, in the short run, you'll get rickets. In the long run, you'll get osteoporosis and cancer and die sooner. And so medicine hasn't really gotten that concept. It's like, yeah, if you're deficient, take a vitamin, but otherwise you don't need them, right? And that's also very much in line with Bruce's triage theory, right? So these micronutrients are running our metabolism, which runs everything from our heart pumping
Starting point is 00:14:49 blood to neurotransmitter function to repairing DNA. So there's a lot of, you know, you can look in the mirror and if your vitamin C deficient and your gums start falling apart, you can see, oh, I've got some. But like when you're magnesium deficient, like you're not going to see DNA damage happening. But you might feel muscle cramps and you might have anxiety. You might have constipation. You might have muscle twitching or headaches or a million other things that are symptoms of magnesium deficiencies. Right.
Starting point is 00:15:16 I mean, the loud noises. And so like as a functional medicine doctor, I take a deep history to look at microRNA deficiency symptoms that are not necessarily pure, true deficiency, but more like insufficiency. And I think people don't make that distinction. And I think when you treat people, it's often a miracle. When you get the pleat in the nutrients are deficient, so many things get better. I like it is insufficiency because most people are not deficient. We do have a lot of fortification even in our ultra-possus foods because of, you know, preventing neural tube defects, sex, preventing pellagra, like all these diseases that were
Starting point is 00:15:53 sort of cropping up, like you mentioned in the early. Fortified. But it's like junk fortified. It is. It is, but it seems to stop some of those deficiencies, right? But it's the insufficiency. And with vitamin D, it's a really big one because it is converted into a steroid hormone. So this is something that is going into the nucleus of our cell and binding and interacting
Starting point is 00:16:15 with DNA. It has a little sequence of DNA called a vitamin D response element. It's so important that it's encoded in our DNA, right? So to not have enough vitamin D, so 70% of the U.S. population is, doesn't meet the sufficient levels of vitamin D, which is about 30 nanograms per mil, 70%, 30, which would be. And if you added up to 45 or 50, it's probably like 80 plus 90%. Right, right.
Starting point is 00:16:42 Yeah. So, and so that would be, there have been studies looking at all cause mortality and vitamin D levels. Of course, this is again, observational, lots of meta-analyses out there, even dating back for like 30 years. And it seems as though having at least 40 nanograms per mil seems. to be a sweet spot. You know, 40 to 60 is a really good place to be where you're having a good level vitamin D. But again, it's a steroid hormone. It's not, it's regulating over 5% of the
Starting point is 00:17:11 protein encoding human genome. That's like thousands of genes. Yeah. You know, everything from immune function, it plays an important role in preventing autoimmunity. Brain function. It regulates genes that are important for converting triptophan into serotonin. Yeah. Serotonin is an important neurotransmitter that regulates mood, cognitive function, impulse control. You know, so vitamin D... Maybe I need more of that then. Well, and the problem is, is that, you know, vitamin D, typically you make it from UVB radiation exposure from the sun.
Starting point is 00:17:40 Yeah. But... We're all told the shielders house from the sun and sun's locked. And so we live indoors, work indoors, and yeah, it's a problem. I mean, we're all running our half-naked hunting and gathering, we got a lot of vitamin D. And we ate, and we're coastal areas, and we ate, you know, fish, small fish, like herring and when they say they're higher in vitamin D or if you're forging mushrooms, you're high in vitamin D.
Starting point is 00:17:59 So there's ways in which our historical population got it, the paleolithic ancestors, but we don't get that. Right. Exactly. We don't. And so, you know, I do think, so people will, the simple solution is a vitamin D supplement, right? And so about 4,000 I use a day will generally get someone from a deficient range, which is 20 nanograms per mill up to a sufficient range.
Starting point is 00:18:20 Okay. But you're just talking about 10 times what's normally in a multivitamin or what doctors will recommend. I am. I am. Because you, yeah, you really do. It's about 1,000 I use of vitamin D will raise blood levels between 5 to 10 nanograms per mill. But it all, we have genes. We have different variations of our genes that are able to do this. And this again comes down to these clinical studies showing that, you know, nothing happens. We're all different. We're all different. And so some people actually have to take a much higher dose, right? Because they have genes that aren't doing, converting vitamin D3 into 25 hydroxy vitamins.
Starting point is 00:18:54 D, which is the circulating form of vitamin D or the steroid hormone, 1.25 hydroxy vitamin D. You know, so... Well, let's put down this rabbit hole because I think, you know, there's a paper just reminded me out of the Bruce James Row that was published in, I think, the American Journal of Clinical Nutrition years ago, about how one-third of all of our DNA codes for enzymes. And an enzyme is a catalyst that converts one molecule to another molecule.
Starting point is 00:19:19 The catalysts or the co-enzymes or the helpers are micronutrients. And so what he said in that paper was that there's a huge variation in the population's need for different nutrients. So some people might need 400 micrograms of folate. Some people might need 4,000 micrograms of folate. And so it's really about personalized nutrition. It's about testing, not guessing. It's about figuring out what your body needs, what your genetics are. And it gets really fascinating that you can actually start to customize your own diet and your own supplement management based on what your own particular genetics and your, your, your,
Starting point is 00:19:53 your levels are do you often feel tired tense or foggy magnesium might be the missing link most people are low and standard supplements don't cut it magnesium breakthrough gives you all seven essential forms and one powerful formula better sleep less muscle tension mental clarity all with no laxative side effects try magnesium breakthrough by bioptimizers at bioptimizers dot com slash hymen for 15 percent off. I think there's this, it was sort of like a wake-up call for me, like, holy cow, when you think of our DNA and everything it does, if one third of it is coding for enzymes and all those enzymes require vitamins and minerals, if we don't have enough of those nutrients,
Starting point is 00:20:37 it's like, it's like an assembly line in a factory. If you don't have one station, the thing can't get made, right? So you gum up the whole works of your metabolic machinery. if you don't have the right levels of nutrients to optimize the function of your body. And that's why we call it functional medicine because it's about how do we optimize function, right? It's true.
Starting point is 00:20:58 You know, these minerals and vitamins, so you're talking about magnesium, zinc, calcium, B vitamins. Like, these are co-factors for these enzymes to make these enzymes run properly. And if you have, if you don't have, you know, sufficient levels of those vitamins and minerals, what happens is those enzymes do not work optimally, right? So in the case that we talked about DNA repair enzymes,
Starting point is 00:21:23 they're not going to be repairing damage as well. Zinc is also involved in DNA repair as well. You know, so B vitamins are involved in serotonin production, magnesium's involved in vitamin D production, right? You were talking about, you know, nutrients working together. And it's very true. So I think a really great way to think about eating diet is what do I need?
Starting point is 00:21:47 to run my metabolism, right? And when you say metabolism, like, what do you mean by that? Because it's not like my weight, you're talking about metabolism as sort of a bigger concept in medicine. Yeah. Yeah, I guess when people hear the word metabolism, they think about weight loss. I got us on metabolism. Right, right.
Starting point is 00:22:05 What I'm talking about is much more a biochemist definition of metabolism, which is all these enzymes. You're talking about, you know, one third of the protein encoding genome. that are doing enzymatic reactions that are making proteins function. So they are producing energy. They are, you know, running neurotransmitter synthesis. They are causing, you know, your liver to function properly, your heart to function, the lungs, everything.
Starting point is 00:22:34 So every chemical reaction all the time. Exactly. I don't know if I heard, I read this somewhere, I can't find the original citation, but that there's 37 billion trillion chemical reactions in the body every second. It's just like an insane amount of activity is going on chemically and biochemically and converting one molecule another. And if you don't have enough of these nutrients, that whole 37 billion trillion chemical reactions may not work optimally. Exactly. So, you know, getting the micronutrients you need from food.
Starting point is 00:23:02 And nature sort of color-coded them in a way, right? I mentioned, you know, chlorophyll, that's magnesium. You have vitamin K, also the chloroids. What color is that? What color is vitamin K? I guess it's green, too. I would say green. Green, great, great.
Starting point is 00:23:18 Vitamin K one. And then the orange ones. The orange, right? And then you've got like the phytochemicals, right? So that would be the purples. But, you know, you really do need to get a lot of vegetables and fruits. And then you need your protein, right? And fiber.
Starting point is 00:23:35 When you're getting your micronutrients, you're also getting the fiber because a lot of the micronutrients are coming from plants. Yeah. Which are a great source of both fermentable and non-fermentable. fiber, right? So I think it's a really simple way. There's so many fad diets out there, right? Carnivore, keto, vegetarian, paleo. And although I do think paleo is the closest thing to what I'm talking about. But what I'm talking about is even simpler because what it really means is that you understand why you need food. What's the purpose of food, right? The purpose of food is to provide you with these essential vitamins and minerals and fatty acids like omega-3
Starting point is 00:24:13 and protein and fiber to improve gut health, that's the purpose of eating. And feel. Right. And so that means you don't need ultra-process foods. That means, you know, if you're eating something like just carnivore diet, you're going to be missing out on a lot of micronutrient. Now, I want to talk about the importance of supplementation and why we need to use nutritional supplements to address nutrient deficiencies that are widespread.
Starting point is 00:24:38 And as I mentioned before, 95% of Americans are deficient and at least one essential nutrient at the minimum level to prevent a deficiency disease. This is staggering. Not how much do you need for optimal health, but how much do you need just to prevent a deficiency disease like scurvy or rickets? And 2 billion people, as I mentioned, worldwide, have at least one nutrient deficient.
Starting point is 00:24:59 It plays a huge role in infant mortality and chronic illnesses around the world. Now, let's talk about the difference between macro and micronutrients. Now, macronutrients, you're familiar with carbs, proteins, fats. Now, it's very unusual in our modern society to have a deficiency in any of these nutrients. Protein is a common deficiency in the developing world,
Starting point is 00:25:18 and you see kids with severe protein malnutrition, but it's really important to get a protein. But although we might not have a deficiency, we still may not be optimal, and I've done podcasts on that, but that's another topic. Now, micronutrient deficiencies like vitamins and minerals are far more common. And I want to explain just for a minute
Starting point is 00:25:34 why nutrients are so important, just to understand the context here. When you look at your DNA, one-third of your entire DNA codes for enzymes. Now, what are enzymes? Enzymes are catalysts. They're basically a enzyme or a catalyst that converts one compound or one molecule to another molecule in your body. They're basically the facilitators of all your biochemical reactions.
Starting point is 00:25:59 And you've got 37 billion trillion chemical reactions happening every second in your body. Now, just that for a second, right? 37 billion trillion chemical reactions every second. And every single one of those reactions requires an enzyme. And those enzymes require a co-factor or co-enzyme. And guess what, folks? What are the co-factors and co-enzymes? They're vitamins and minerals.
Starting point is 00:26:31 Now, drugs, they affect a single pathway to create a single outcome. For example, if you have a blood pressure pill, it's a calcium channel blocker. It does that one thing. However, vitamins and minerals, they might have the effect on hundreds and hundreds of different enzymes. So magnesium or folate or other other nutrients may have the ability to affect the function of literally hundreds and hundreds of different chemical reactions. That's why they create such widespread problem. So just to understand that this is a super important thing and based on these genetic differences we have, you know, I said one-third of our DNA codes for enzymes, based on
Starting point is 00:27:10 these genetic variations, different people may need different amounts of nutrients and may need different forms of nutrients. For example, if you have a gene that is called MTHFR, it means you can't convert the folate from your food very well into the folate that's active in your body five methylfolate. So you need to take the preformed version as a supplement, for example. Or let's say you are somebody who has vitamin D receptor issues and can't absorb vitamin D well, you might need not a thousand units of vitamin D-Date, you might need 10,000. And so there are a lot of variations in the population. That's why it's important to test, not guess. And again, that's why I created with my colleagues and friends and co-founders, Functionhealth.com, to allow you to get all these nutrients
Starting point is 00:27:55 we're talking about today tested and many more. You go to Functionhealth.com forward slash mark and you can find out what's actually going on. Okay, so let's get started. What are the most common micronutrient deficiencies. Well, iron. Iron is the most common nutrient globally, affecting about 25% of the global population. Now, the consequences include short-term problems like anemia, particularly in preschoolers, where nearly 50% are deficient if they're not getting iron fortified foods, right? So the at-risk groups, particularly are vegans, almost all the vegans I know and test are iron-deficient. Vegetarians still, menstruating and pregnant women because they use up a lot of blood in either menstruating or, you know,
Starting point is 00:28:36 creating extra blood for the baby. Vitamin D deficiency also extremely common. And it may have, depending on how you look and define it, insufficiency or deficiency may affect between 80 to 95% of the population. And we're going to put all the references in here. I'm not making this stuff up. You just have to look at the show notes to get the scientific papers that are reflecting what I'm talking about here. Now, while frank deficiency symptoms like Ricketts are not common today, although they are sometimes in the developing world. Suboptimal levels have significant health impacts. As I mentioned, suppressed immune system, muscle weakness, fibromyalgia, fatigue, depression, immune dysfunction, and even cardiovascular risk, cancer risk. I mean,
Starting point is 00:29:17 all these things are related to low levels or insufficient levels of vitamin D. The next big one is magnesium deficiency. Now, this affects about 20% of the population based on the minimum amount to prevent a deficiency disease. That's 20% who have overt magnesium deficiency. That's quite serious. Subclinical deficiency could affect up to 80% of the population, which is very important because why? Magnesium is crucial for over 600 enzyme reactions affecting every single biological system, affecting overall health and risk of chronic disease. Literally everything from your mental health to your immune health to metabolic health, diabetes control, muscle function, Everything, pretty much everything.
Starting point is 00:30:01 Vitamin B12 deficiency is also really common. About 80 to 90% of vegans and vegetarians may be deficient in vitamin B12 because there's not any vegetable food, basically. That's how it is. Just back to life. Now, over 20% of adults may be deficient in not the vegans, because it's only about 2% of the population of the population. But basically, even the rest of the population, it can be deficient in vitamin B12.
Starting point is 00:30:23 Part of it has to do with, you know, our drugs we're taking like acid blockers. part of it has to do with our digestive function and lack of absorption in some cases, or just lack of intake, right? Because we aren't eating B12 foods. Now, what about calcium deficiency? Not that common because the body regulates calcium pretty well from the bones. But what happens is basically, if you don't have calcium, because your blood levels have to be controlled really tightly, it just sucks it all out of your bones and you get osteoporosis. But a survey in the United States found that about 50% of teenage girls and about 10% of women over 50 and about less than 22% of teenage boys and men over 50 meet the recommended calcium intake.
Starting point is 00:31:03 So a lot of people don't meet it. And it depends on your age and your sex and so forth. But we need to make sure we have adequate calcium. But ideally you want to get it from food. Calcium-rich foods are really common. Greens, often seeds. Sesame seeds are great. Chia seeds are great. So there's a lot of ways to get calcium. You can get it from bones from can of sardines which I like, but anyway, you probably don't like that. I like to eat that. can of salmon with the bones in. Again, that's how people lived on islands used to get calcium. Anyway, you can take a little calcium,
Starting point is 00:31:32 but I don't think you want to overdue on a calcium because of problems with calcium affecting the heart and creating other issues. So I'd be careful about that. Anyway, omega-3 fats, the next one. This is a big one. We don't eat the foods we used to eat as hunter-gatherers, which are wild foods or a lot of sea-based foods for coastal people.
Starting point is 00:31:52 Those are very rich in omega-3s. but our modern industrial diet and our lack of intake of wild fish has really dropped. And so 90% of Americans are not meeting the recommendations for omega-3 intake, which is one serving of fatty fish at least two times a week. I think that's a bare minimum, right? And I'm talking about like sardines, herring, mackerel, maybe some wild salmon, anchovies, you know, small fatty fish. Now, there's a lot of other deficiencies.
Starting point is 00:32:18 And this is from a large national study is called the N. Haynes, or National Health and Nutrition Examination Survey. It's a big mumbo-jum, but it's a government, ongoing government study that's been going on for a long, long time that tracks people over decades, tracks their blood work, their health issues, and basically they found that 45% of the population is deficient in vitamin A, 46% in vitamin C, 84% in vitamin E. Why? Because it comes from whole grains and nobody eats those. 15% are deficient in zinc. And why this matters is that these subclinical deficiencies or just frank deficiencies, can lead to really serious health consequences, and they may not
Starting point is 00:32:55 have initially obvious symptoms, but they will ultimately. So what's the truth about supplements? Well, getting in a vitamins and minerals is not just about preventing deficiency diseases. Well, that's part of it. They're also essential nutrients to power every aspect of our biology, as I said, right? Vitamins and minerals and amino acids play key roles in a whole set of biochemical reactions in the body. As I mentioned, they act as cofactors. I'm just saying this again because it's so important. you understand they literally are the grease that lubricates the wheels of our massive metabolic and biochemical machinery like the power metabolism our detox systems our energy production our antioxidant systems which all are important for overall health i mean your antioxidants
Starting point is 00:33:36 need nutrients to work for example you need zinc and copper to activate in manganese one of the most important intracellular antioxidants called superoxide dismutase so nutrients are key for everything right For example, you can't make ATP for energy for yourselves without magnesium. If you want to turn tryptophan from your turkey into serotonin, which is good for your mood, you need B6 for that chemical reaction. And you need magnesium and you need folate. So if you have low in those and they're really common to be low in, of course you're going to be depressed. You want to make thyroid hormones, right?
Starting point is 00:34:08 To make thyroid hormone T4, you need iodine. And then to make T3, you need selenium and zinc and vitamin A and vitamin D to make the thyroid hormones. hormone work at the cellular level. So without optimal levels of these essential nutrients, our biochemistry just can't function properly. And that leads to these low level functional imbalances. And they manifest as just feeling crappy right now. I can call it feel like crap syndrome or FLC. Or worse, they can lead to these long latency deficient diseases, accelerated aging, heart disease, cancer, osteoprosis, depression, and worse. And also they lead to immune dysfunction. That's why they elderly often having a higher risk of illness, infection, because
Starting point is 00:34:50 they tend to, you know, have poor diets. They tend to have trouble absorbing nutrients in their stomach as they get older, and so they tend to have more deficiencies. Now, a new study published in the European Journal of Nutrition studied blood levels of magnesium, really important, my favorite mineral, and homocysteine, which is a measure of B12 folate and B6 function in the body. And they looked these levels in about 172 healthy middle-aged people from Australia. And they found that low levels of magnesium and high homocysteine were linked to an increase in DNA damage. Now, what is the minimum RDA for magnesium? It's about 400 milligrams, which is fine. That's a pretty good amount. But here's the deal. In order to get that much magnesium, you'd have to eat 115 almonds, seven avocados,
Starting point is 00:35:35 and 12.5 bananas to meet that amount of magnesium. And that's why supplementing is so much. important in today's modern world. The question is, do Americans need supplements? Do people, in general, need nutritional supplements? Because if you listen to most doctors, you don't. I mean, I think that is the thing that is so hard as a consumer in the space is just the wildly different opinions. And like, it's the doctor gap of people who say expensive urine to the ones who are like,
Starting point is 00:36:07 this is exactly what to do for this. And it's also like the explosion on social media, you know, there's a, this whole kind of n-equals-one world right now where people are raving about, you know, this supplement is just changing my life. It makes me seen 4K. But, you know, then they also have their supplement store right behind it. So it's an extremely difficult space to navigate. I mean, there's a lot of snake oil sales, but a lot of snake oil sales. Yeah. Or, and look, there might be people who are having actual real great experiences, but they're not aggregating that data in a way that, you know, allows anyone to make sense of it. It's just their individual
Starting point is 00:36:37 story. And I think we're going through such a big, you know, battle right now in America. around the individual and the institution, right? And, like, who to trust in this? And that trust is really a road. Institutional trust is, you know, continuing to go down. And, you know, 51% of Americans say that they have bought a health or wellness product from a social media influencer. Yeah.
Starting point is 00:36:57 From something I saw on social media. Well, I bought shorts and shoes. Yeah, yeah, fair, fair. I see, well, kind of dive a little bit deeper for us into what is subcoe and how it works and why is so important? You know, we like to say that we're helping users make sense of supplements. Through our website and app, we're helping you figure out what supplements are right for your health, what products and brands you can trust, how you can save the most money and get results. To do this, we've cataloged over 200,000 supplement products that you can search in our app or by their scanning the barcode.
Starting point is 00:37:27 And we've built an in-depth trust score rating from 29 different attributes that lets you understand the manufacturing standards and quality of your supplements. For those looking to figure out what they want to take, we have 80 expert protocols that you can go in to. to find guidance on different health topics like brain fog or heart health and women's hormones. To get starting, it's pretty easy. You enter a little bit of information. Start scanning your supplements to kind of catalog what you're already taking.
Starting point is 00:37:54 We give you an analysis of your stack so that you can kind of get a score that's easy to understand how you can improve quality, how you can improve trust, and make changes to kind of improve that. You also then can share your stack with your doctor, your friends, kind of get feedback from different people, create a conversation around it.
Starting point is 00:38:11 That helps you understand if you're taking too much or too little of something, which, you know, happens to a lot of people. And then we have a smart scheduler that lets you make sure you're taking your products correctly. Are you taking them with food? Are you taking them at the right time? Which, you know, will then also start tracking to see whether or not you're getting results. We launched a beta in early October. The response has been amazing.
Starting point is 00:38:32 We're getting like nearly 1,000 users a day right now. October 24. October 24, yeah. And we're getting a thousand users a day without even having your protocols or excited to get your protocols and stack on the platform soon. And I think what's for us people to know, right now, everything on SUPCO is free. And we'll launch a premium membership later this year, which will have some premium features and eventually help people save money on their supplements as well. We don't sell any of your data. There's no advertisement on SUFCO either. And yeah,
Starting point is 00:39:01 we want people to come in and be aligned with them so that we're just as excited when they stop taking something that doesn't work as when they start taking something. So you're not selling We're not selling supplements, and if we do, we will never profit from them. You're guiding people on how to take the best products for them that are the cleanest that are actually matching their goals and needs, and you're just providing this incredible service, which I think is such an important gap in the marketplace that you're filling. So what is the problem of nutritional deficiencies today in America? What do we know about the level of insufficiency or deficiency of nutrients?
Starting point is 00:39:39 Is it widespread? Is it rare? I mean, look, I think this is your world. I think this is the one that you particularly would talk best about. I know my own individual struggles, but honestly, like, you've got this data. This is your world. I mean, the data is so impressive. You know, when you look at the, and I'll just sort of share a little bit to kind of set the stage. But, you know, N. Haynes is called the National Health and Nutrition Examination Survey,
Starting point is 00:40:00 and it's conducted by the government. And every year they drive around, they get blood on a whole bunch of people. They chest their levels and they see what's going on of all sorts of things. And nutrient levels. And what they found is, you know, 90 plus percent of Americans are efficient in one or more nutrient at the minimum level to prevent deficiency. And this is really an important concept for nutrients because if you look at, for example, vitamin D, you need maybe 30 units so you don't get rickets.
Starting point is 00:40:27 Right. But you might need 3,000 units so you don't get osteoporosis or cancer or dementia or heart disease or autoimmune diseases or a whole bunch of things that we call long latency deficiency diseases. There's a guy named Robert Heaney, was a professor and brilliant scientist who wrote a paper called Long Latency Deficiency Diseases. What essentially was talking about was like, yeah, there's nobody walking around really in America with rickets anymore or scurvy or Berry Berry or Pallagra or Xerophthalma. These are these severe deficiency diseases that we actually found in the turn of century when we started refining our diet and taking
Starting point is 00:41:06 white flour and white rice. That's actually how they found it. It was in prisoners. They gave them white rice. They all became deficient and had these horrible diseases that were cured in a second, essentially with minuscule amounts of nutrients. When you look at the amount of deficiencies, whether it's, you know, 90 plus percent deficient omega-3, 80 plus insufficient deficient vitamin D. And some people say even more. Magnesium is about 45 percent. Zinx about 40 percent. Iron. You know, we have a lot of efficiencies. And with function, You know, we now have 150,000 members at Function Health. And now, by the way, there's no waiting list,
Starting point is 00:41:42 so you can just join, go to FunctionHealth.com slash mark. You can get in and go ahead and check your levels. But we found that in looking at all the data, almost 70% of our members have a deficiency in a nutrient that is at the minimum reference range of the lab. So in other words, for iron, this is an example, your ferreton level, which is your iron source, should be 45 or more to feel good, to not have fatigue,
Starting point is 00:42:09 then not have hair loss, to not have insomnia. There's a whole bunch of things that come with low iron. The reference range goes 16 or lower, but it should be 45, right? Or homocysteine, it's just like the levels 14, which should be more six to eight, which detects be vitamin deficiencies. Or vitamin D should be probably 45 to 60,
Starting point is 00:42:30 not 30 or 20, which some lab reference changes are. And at the minimum level, which is how much you need to not get rickets or scurvy or any of these diseases, this is what the RDA is. It's not the amount you should be taking. It's the minimum amount you need to be taking so you don't get some of these horrible diseases. We're seeing almost 70% of people are deficient in these nutrients in a cohort of 150,000 people, which is a massive amount of data that we've collected at Function Health.
Starting point is 00:42:56 And we're learning about the kinds of things we're seeing in the population. So it's a real issue where people are not getting the nutrients they need. and they don't know why they feel bad. They don't know why they have these low-grade symptoms. You know, I had one patient, she came in. She was a radiation oncology resident at Mayo. And she had the most severe migraines. She was on narcotics.
Starting point is 00:43:18 She was on, you know, major anti-vomomiting medication. And she could barely function. And she came in and she said, oh, I have terrible migraines. And I started taking her history. I said, oh, you have other symptoms like constipation or do you have muscle spasms or do you have anxiety or irritability or palpitations or constipation
Starting point is 00:43:41 and she's like, yeah, I got all those things. I'm like, well, that's a magnesium deficiency. And it was so easy. And she needed like a thousand or more milligrams of magnesium to get her going and to clear everything out. And then cured her migraines. And you hear someone who was at Mayo Clinic,
Starting point is 00:43:55 saw their best migraine doctors, did everything she could. They couldn't even diagnosis. And by the way, magnesium deficiency, we test magnesium with, and we get your red cell magnesium, which is a better indicator. Sure. But to do a real magnesium loading test where you give people IV magnesium
Starting point is 00:44:09 and you see what they keep and what they dump out is the best way to actually really tell. But even so, just by history, I could tell. And after doing functional medicine for 30 years, I can tell you without a doubt and doing nutrition testing on tens of thousands of people and deep analysis of minerals and vitamins and the oxen levels and oxidative stress and Tokutin,
Starting point is 00:44:27 all the things that people normally don't look at. It's so widespread. Like nutrient deficiency is so widespread. in America. So, you know, that kind of then leads into the question of, well, if that's true, then, you know, why is that true? By the way, what's shocking about that is, 75% of Americans take a dietary supplement, 55% of regular users, yet 70% are still getting those lab results from it. So, like, they're definitely taking the wrong things or not enough of the right things, you know? Like, so I think that just speaks to a lot of the, you know,
Starting point is 00:44:55 stuff we're trying to sort out, Subco is giving people the ability to actually know what they're putting in their body. One of the big features of being able to kind of enter everything, that you're currently taking is you'll actually see your nutrient totals across all the different products. Vitamin D is coming from six of the products I take, you know, and like actually having a conversation with a doctor about what's actually going in your body. Right. Doesn't really happen.
Starting point is 00:45:16 I remember talking to a nutritionist in the beginning. They're like, she was like very good. She said, yeah, I would spend four hours, you know, actually going over the nutrients that people were getting from the products they told me. But most people don't ever do that. I don't know who has a conversation with their doctor, who knows actually what they're putting in their body. No, I think this is really important.
Starting point is 00:45:31 So SEPCO is your company that you started to help solve this problem of what to take, quality. Quality, yeah. How can you trust what you're taking? You know, what's the total amount of nutrients you're taking? So people might be taking 10 different supplements and they, like I said, they all might have selenium in them. Correct. And then you're getting toxic dose of selenium. 100%.
Starting point is 00:45:49 And you don't know that because you're not adding it all up. You're not putting a spreadsheet. You're not doing the math. And you create a product that does this. Now, I believe in this so much because it's what I tried to solve when I started my own sort of store for my patients, which was essentially trying to curate a small group of products that I personally had investigated, that I visited the factories, that I did the analysis, that I looked at the third body testing.
Starting point is 00:46:09 My God. I mean, I curated basically three, 400 products for functional medicine applications for basically helping people with, you know, cardiometabolic issues, for hormonal issues, for gut issues, and so on, so forth. So that was a lot of work. And, and I've been confident that I can recommend these things to my patients or, you know, people who follow me, but I don't think it really solves a bigger problem of, like, how do you figure out everything altogether? And I know personally that I don't have enough time to do this
Starting point is 00:46:39 for myself even. Totally. I'm buying different things. Are using things. Right. They're like, how do I, how do I know? So that's really why I become an advisor to SUPCO and I'm sort of helping you because I think this is such an important gap in the marketplace and it's such a need. When you look at the landscape today, tell us some of the problems in the supplement industry. Why why is this needed? Because people are just buying stuff and they don't know where it's coming from, where they get it. They can buy it on Amazon. And often this stuff is sitting on a palette for a long time or it's like it's some sort of rip-off product that doesn't have the nutrients in it. So tell us sort of unpack the real issues with the supplement industry
Starting point is 00:47:15 as it is today. As I said, we've got about 200,000 products. There's like 195 already done and then a big queue of ones that have been submitted to us that we're going through. And that's up from 4,000 products in 1994. That's all there was. Right. So it's been a, 4,000 to 200,000. In 1994, there's 4,000 supplement products on the market. And now there's over 200. That's insane. And so, you know, we've kind of gone in and taken each one of the supplements, taken the supplement facts labels and kind of taken the data so that you can get an aggregate view of, you know, what you're actually put in your body. So that helps you understand what you're taking. But addition to that, we've gone out and scored the top,
Starting point is 00:47:50 there's 8,000 brands, which is insane too, if you think about it. We've taken the top 500, which covers, you know, a big percentage of it and kind of expanding down the long tail now. And we've given them a trust score. And so we basically have gone in and done what you were doing kind of manually and doing all these individual reviews. About the 29-point system that goes in
Starting point is 00:48:09 and, you know, checks what certifications, what kind of testing they're doing and kind of breaks it down and gives them a score. That alone, that feature alone, you can scan any, you know, supplement for its barcode. You just take the bottle, you put your phone on it. You can do it here while we're talking to. Yeah, it's pretty, it's pretty.
Starting point is 00:48:24 It's a pretty cool thing. You don't have to, like, manually enter it. You just scan your code and it. You scan it, it pops up right away, and, you know, you get the trust score and all the information about the product. It's super fast. It's super easy. And the hit rate is really high.
Starting point is 00:48:37 And if we don't have something, you immediately can submit it. You can AI scan the label and it'll put it in the system. And the queue is insane. Like the long tail here, there are 20,000 products in the system that only one person is taking. There's a long tail here that is, you know, absolutely insane. And that's, there's unique products that are kind of not commonly taking that. Yeah, they're like one person's taking.
Starting point is 00:49:00 I don't know how they found it. I don't know if that's a trusted brand. And you've seen an explosion on Amazon of these kind of brands that are just quickly coming to market because there's no real thing stopping you from bringing a supplement to market. You know, there's a big difference in the FDA around the federal code between pharmaceuticals and supplements. Supplements are governed under federal code 21 CFR-11, right?
Starting point is 00:49:23 What is that? And that's basically that, like, you know, for pharmaceuticals, there's a whole process that they have to get pre-approved following CGMP standards and all these different things. That's good manufacturing standards. Yeah. Current good manufacturing process. You know, with supplements, it's not something that gets done up front. You can be held to this standard retroactively, like if something comes up, but it's kind
Starting point is 00:49:46 up to you to just say you're doing this. You can get retroactively. Someone can say they're having a negative experience reported with the FDA. can come after you for not following the practice, but no one's checking up front. I mean, the amount of attention that the FD PACE this is very, very little unless there's some serious adverse effect or somebody has this problem with it. Right. And those latent things you're talking about, the like ones that might be heavy metal exposure
Starting point is 00:50:07 that take a long time to ever show up or you don't know the source of it. There's no guideline. I mean, a friend of mine was a researcher and he actually analyzed Aruvadic supplements and found extremely high levels of heavy metals in it. Totally. So you're like, you're taking some Arubatic earth. which is some natural product, and it hasn't been tested properly. And when they actually tested it, it was full of heavy metals.
Starting point is 00:50:27 And even if you follow CGMP, you're supposed to occasionally test your lots. I think it's like once a year. And then even then, they don't provide the guidance on heavy metals. It's like kind of up to you to be like, well, for this type of product, what should the... Prop 65 helps a little bit, you know, in terms of making sure you don't have to put the label on there if you exceed those numbers. But it's a pretty wild west, to be perfectly honest. And there is. There are systems now that can say come up with an idea and a brand, and you can you,
Starting point is 00:50:53 and get a supplement market in weeks. So that's why you're seeing the explosion. Yeah. So we've gone in and we've taken 29 different points and we've built the scoring system. This is your trust score. This is our trust score. So basically you're taking 29 different attributes, you know, whether it's toxic. Lot testing, CGMP.
Starting point is 00:51:09 If whether the biggest one that makes a difference is whether or not you're getting a third party to certify your CGMP practices, right? That's like kind of like the fundamental. So instead of you just saying, yeah, I'm good, you know, I'm a self-certify that I'm following these practices. is there's NSF and UL, these two big firms that'll come in and do what you are doing, you know, go toward the facilities, kind of do, make sure you're actually following, give you a certification.
Starting point is 00:51:32 That's like a fundamental big one, and there's a surprising number of brands that don't follow. And that means the manufacturing plan is clean. Oh, yeah. The way they get sourced the ingredients. They're testing each lot, you know, and like there's a lot, you know, to that to figure it out. That's true. When I started in this field in functional medicine 30 years ago, there were a handful of professional brands that were only marketed and sold through professionals, doctors,
Starting point is 00:51:58 nutritionists, and so forth, chiropractors. And you couldn't get them otherwise. Interesting. You couldn't get like metagenics or Thorne or Pure Encapsulations. They only distributed them through doctors. They only distributed them through professionals because they were higher level, higher grade, a little more expensive, but you get what you pay for. So, for example, peer encapsulations, they may actually test every single product, every lot,
Starting point is 00:52:20 and what we do it before they make this stuff with the ingredients and they do it after. And if it says, you know, it's supposed to say 400 milligrams of, let's say, magnesium on the label, if it's 350, they throw it out. Metagenics, who you brought up is our 10 out of 10. They're our highest scoring brand on the platform. Yeah. They do like one thing that is rare, but we really, we give some points to it is they make every batch test COA publicly available. So you can look at your bottle, look at the lot number.
Starting point is 00:52:50 go online, pull it up, and see the results from the test. That's like a gold standard for us. Pure ranks very highly, but then there's a big spectrum, you know? I mean, and the stuff that you get in the grocery store or Walmart or the drugstore is generally crap. Like, you sent me, they texted me a screenshot of Centrum. Yeah, we just did not have on this. This massive advertising, it's really a big product out there.
Starting point is 00:53:16 Everything's Centrum. It's high quality. I mean, but they've got, why do you take it? a blue pill or a red pill or have titanium dioxide or have dyes and chemical. Yeah, that was a super interesting thing about that centrum pill in particular is that like the centrum brand ranking is pretty high, but we just started exposing the excipients, the inactive ingredients. Yeah.
Starting point is 00:53:35 And it had titanium dioxide, red 40, red five, like these things that, I'm sorry, yellow five, these things that are that are not good. I mean, titanium dioxide is not, it's banned in Europe, you know, like it causes DNA damage. and they don't need to be in your supplements. So that's another thing we just rolled out was not just the manufacturing standards, but now we're going down to the product level and actually going in, we have like,
Starting point is 00:53:59 forget how many, it's a couple thousand of these excipients that get added and branging them out by, you know, how cautious you should be about. Yeah, and there's a lot of stuff in them that we often are not known. Like there could be gluten or dairy like lactose or other things that are in these,
Starting point is 00:54:13 in addition to all the other kind of excipients, fillers, additives, colors. chemicals, things that make it look good or stick together. And I mean, you don't want that crap. You want the nutrient. And I think it's going to be interesting. We're starting to send out, you know, different supplements for our own independent testing to do what you were saying.
Starting point is 00:54:31 Just kind of like verify that even if they're highly rated, are they, is it actually in there what they say it is, right? So the precision of the nutrients that they're claiming are in there. It's a complicated market. And I think that what we've done, though, by just making a simple score, like making it out of 10 is like it makes it really easy for people understand. Right? The simple like red, yellow, green, like you can go deep and you can go look at each of the 29 points. Your trust score is one to 10. Like this is a nine, this is a two. That has been helpful for people to just like simply take a glance.
Starting point is 00:55:00 Because some, the user base we have, you know, one thing I like doing in general when designing software is it's got to be easy enough for, for grandma to use, but powerful enough for, you know, the most hardcore user in the space to go deep on, right? I did that with, with Splice, making sure that 40% of top 40 music using it to create music. They're like the hardcore guys and the brand new music creators, right? So we're doing this in supplements, right? There's a, there's a way to dive way deep into what those 29 points are and each one of the exhibits and all that. Or you can simply look at the score at the top and be like, okay, that feels good. Because Some people just, we got to meet the consumers where they are. Because nobody's really doing that. There was a company called Consumer Labs that I used to kind of use to reference stuff where they would go and test products and I would rely on their independent analysis. But, you know, they weren't able to do the 200,000 products. So you basically, just for the simple scan of the barcode, the technology behind it, the use of AI. I mean, it's quite amazing now.
Starting point is 00:55:56 You can literally see what is the problem or how. good a product is and whether or not it's actually says what it is in the label. Yeah. And like I think the big thing too is like we're not out here to we just want to kind of arc the industry in the right direction. Right. Like some of our trust scores if we find a negative one, we're not all doing the big gotcha, you know, story on it. We're having conversations. A lot of the brands have reached out to us. First, the top end brands are like, thank you. Right. Thank you for simplifying and raising to the attention how much work we are putting into testing this. So like super appreciative, you know, sometimes they'll clarify a piece of data that we might not have right
Starting point is 00:56:33 because we've collected it through our teams, you know, reaching out to them, and they might provide something, which is great. And then we've had brands also reaching out, one, they want their trust work, because the consumers are starting to care about this. And then how do we make it better, right? And that's our big dream. If we can just help the industry move in the right direction on this, with the scores, I think we've done something really great.
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