The Dr. Josh Axe Show - Big Pharma, Gut Health, and Longevity | Dr. Will Cole on Thriving in a Toxic World

Episode Date: October 31, 2024

Discover the secrets to reversing chronic disease and unlocking optimal health in this episode of the Dr. Josh Axe Show. Join us as we welcome Dr. Will Cole, a leading functional medicine expert and b...estselling author, to explore the cutting-edge intersection of gut health, longevity, and holistic healing. Dr. Cole, renowned for his innovative approach to treating autoimmune disorders and metabolic dysfunction, shares his wealth of knowledge on achieving vibrant health in today's toxic world. Prepare to be enlightened as we dive deep into: The shocking truth behind America's chronic disease epidemic and how to protect yourself Revolutionary insights on the gut-autoimmune connection you can't afford to ignore The hidden hormonal imbalances sabotaging your health goals (and how to fix them) Game-changing dietary strategies to boost longevity and enhance your healthspan The mind-body-spirit trifecta: Unlocking the ultimate healing potential within you Stress-busting techniques to reclaim your metabolic health and hormonal harmony The power of targeted supplementation in supporting your journey to optimal wellness Don't miss this transformative episode that could change the course of your health forever. Tune in to arm yourself with the knowledge and tools to take control of your well-being, prevent chronic disease, and unlock the vibrant, energetic life you deserve. Your path to lasting health and longevity starts here! Want more of The Dr. Josh Axe Show? Subscribe to the YouTube channel. Follow Dr. Josh Axe Instagram Twitter Facebook Tik-Tok Website Follow Dr. Will Cole Instagram Facebook Twitter YouTube ------  Links:  Check out Dr. Will Cole’s Podcast → The Art of Being Well Submit your questions via voice memo to be featured on the show → speakpipe.com/drjoshaxe  Ads Even if your bloodwork looks "normal," your symptoms could point to Cell Danger Response (CDR). Discover how to break free from CDR and unlock your full potential at beyondbloodwork.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript
Discussion (0)
Starting point is 00:00:00 It's unsustainable the way that we are living today. The statistics speak for themselves. So 50 million Americans having an autoimmune condition, infertility as of epidemic levels, about 93% of the United States has a massive metabolic problem. Somewhere on the insulin resistance spectrum, type 2 diabetes being the sort of the farther end of that, I could go on and on. Heart disease, cancer, it is unsustainable. These are existential issues.
Starting point is 00:00:27 It's even more polarizing and different when you go to Europe because if you're looking at the food in Italy and a label of food, the exact same product in the U.S. has so many more chemicals, so many more artificial ingredients, so much more sugar. Our soil microbiome, it's the things we're spraying on our foods. It's the additives that are added after it's grown. These are proverbial check engine lights to say, look, yeah, you're aging faster than you need to. Just because something's common doesn't necessarily make it normal.
Starting point is 00:00:54 Hey, everyone, welcome the Dr. Josh Axe show. I am your host, Dr. Axe, and each and every week on this show, show we dive deep into the science and principles behind how to grow in body, mind, spirit, and take your health and your life to the next level. Today, I'll be interviewing my friend Dr. Will Cole. Dr. Will is a doctor functional medicine. He was one of the first doctors to go online and start taking care of patients from all over the world virtually.
Starting point is 00:01:20 He's a New York Times bestselling author of books like gut feelings, ketotarian, and the inflammation spectrum, one of my favorites. And today we're going to talk about all things, longevity, women's and male, hormone health, gut health, and so much more. Dr. Will. Hi-five to you. Good to see again. Hey, I see you. This is the first time that we were recording in person.
Starting point is 00:01:40 I think after all these years, we're always remote. I'm glad this is the day's finally here. Yeah. We're always hanging out offline, but now it's just like we're in front of millions of people. So good. That's what we're doing with the podcast now. I wanted to do, I love this being able to connect with friends and be able to hang in person. And so it's so good.
Starting point is 00:01:57 But I was so jealous this week of you. I saw you in Milwaukee doing an event. And I know that this is something that people really, a lot of people feel struggling about you and I both do, is trying to get America healthy again. So many people today are suffering with chronic disease. And part of it is due to a lot of government regulations. I mean, I saw a friend of hers, Vonnihari, yesterday.
Starting point is 00:02:21 She was actually speaking at a Senate with RFK Jr. And they were going through. And one of the things she did is she held up a back. of fruit loops. Yeah, I saw that. From Canada and another from the US. And the difference was absolutely crazy. Yeah.
Starting point is 00:02:39 And so talk to me a little bit about sort of your involvement, sort of going between the, not taking political sides, just saying we've got to help these kids, we've got to help America get healthy again. Share with me a little bit about your passion, your thoughts about what's going on right now with that. Yeah, I mean, it's unsustainable,
Starting point is 00:02:54 the way that we are living today, the statistics speak for themselves. of 50 million Americans having an autoimmune condition, infertility of epidemic levels, about 93% of the United States has a massive metabolic problem, somewhere on the insulin resistance spectrum, type 2 diabetes being the sort of the farther end of that. I could go on and on, heart disease, cancer, it is unsustainable. These are existential issues. So this should be a completely nonpartisan issue.
Starting point is 00:03:24 The fact that it's been politicized or the fact that there's any pushback on this, says more about the people that are pushing back than us talking about the health of everybody, no matter who you are, as just a human being, I want you to live a long healthy life. And the statistics say, we're not. So what can we do about it? And we need to know what we're up against to do something about it. So there's just a coalition, I think, of different people from different backgrounds within health and wellness and science and nutrition that we're asking the questions.
Starting point is 00:03:57 And we're not only asking the questions, but people like you and I are seeing these things on the ground with people. And we look at the labs. And these are largely overcomable, healable, reversible things, but there's just not conversations. So, yeah, look, I'm in health. I'm staying in my lane. But this is, and I don't see this as a political issue other than it's really a human issue that is we're having conversations within the political sphere. Yeah. Yeah, I was watching this interview with RFK and he was talking about how the autism spectrum disorders. I mean, how the numbers have grown. I mean, it's absolutely
Starting point is 00:04:38 mom-boggling. It went from something like 1 in 1,500 to 1 in 32. I mean, the numbers are crazy. And he was just talking about how, I mean, you think about those kids. And, you know, I think there, there are multiple root causes. I think I'm not going to name all of them because maybe if I name one of them, this won't be able to be aired. But, but anyways, there's a lot of it. of things toxicity-wise, things that affect our immune systems, and some of it could be food, could be antibiotics, and other things that I think have a negative impact on the immune system. He was just talking about how a lot of this is preventable. That's the whole thing. A lot of it's preventable. And I know recently, Chelf's and I, we went on a trip to Europe this past summer.
Starting point is 00:05:16 And it's the same, you know, we were talking about this with Canada. But it's even more polarizing and different when you go to Europe. Because if you're looking at the food in Italy and a label of food, the exact same product in the U.S., has so many more chemicals, so many more artificial ingredients, so much more sugar compared to what you're going to get in Europe. And it's just, it's just radically different. It is. And hopefully we can do better. I see this with telehealth patients where they can go to Europe and they could get away with things eating-wise that they could never get away with here. That's right. And it's to your point of the things you're talking about. It's our soil microbiome. It's the things we're spraying on our foods. It's the
Starting point is 00:05:54 It's the additives that are added after it's grown. So it's a confluence of factors. But the reality is it's just these are questions that are not even looked at. People, no matter who you are, if you're not in health and wellness, if you're just like the average person out there, you're going to say, yeah, the statistics speak for themselves. But it's not enough to say, yeah, we see more and more people have chronic disease. We have a chronic disease epidemic. More and more kids are having food sensitivities and allergies and these autoimmune problems.
Starting point is 00:06:23 But why? And I think that we have to go to the extra level and say why, because there's a reason. There's a reason for it. And it's multifaceted like you touched on. But yeah, if we're not going to have this conversation, who is? Yeah. It's what we do. You know, when I first opened up my practice in Nashville when I saw patients in person,
Starting point is 00:06:42 I was so shocked by how many people were coming in with certain types of conditions. When I see people now, it's almost 20 years later, it's very different. I mean, there are certain conditions that are so much more prevalent today than there were 20 years ago. What are some of the most, as we talk about processed food, a lot of chemicals like glyphosate, all these things that we're exposed to now, what are some of the conditions over the last 10 years that you're saying, okay, I've seen this in my clinical practice. It's increased due to a lot of the toxins and some of the other things we're exposed to. Autoimmune conditions as a whole, and that's a broad umbrella of things. I mean, as I mentioned, it's estimated that 50 million Americans have an autoimmune
Starting point is 00:07:22 condition. Millions more are somewhere on this autoimmune inflammation spectrum. But the most common ones are Hashimoto's, autoimmune thaditis, lupus, ulcerative clitis crones, MS, chogrin's, rheumatoid arthritis. Those are the most common ones out there. I probably missed a few.
Starting point is 00:07:40 But I would say we've seen, and the statistics show, we're seeing an increase of this around the world, autoimmune conditions. But I would say, A specific type of autoimmune condition that I am seeing more since COVID, since 2020, the pandemic, is potts, posto-orthostatic tachycardia syndrome, people that have dysototidomia. The nervous systems is regulated. And now studies are substantiating that, that a broad swath of people after COVID don't recover, and it triggers, the virus triggers an autoimmune condition.
Starting point is 00:08:15 It can trigger other autoimmune conditions, but a bigger percentage of them, I have this sort of vertigo, nervous system dysregulation, heart palpitations, anxiety, brain fog, fatigue. And there's an inflammatory component. There's a histamine component to it. So I would say if you look at a very specific thing that I've seen growing over the past, not just 10 years, or the past five years, four years, it is pot specifically and dysodotidomium. You know, one of the things is I've studied a lot of Chinese medicine over the years, and I know this is something you've jumped into as well. is that when we look at what COVID did to people, for the most part, it caused the blood to congeal and get sticky. And this is why it's causing a myocarditis. It tends to be connected with heart issues, but also issues regarding the nervous system because when your blood gets sticky like that, it causes some of those issues.
Starting point is 00:09:03 That's why some of these supplements or herbs or foods that help with that, like a corsotin or a tumor or in nanokinase is another one that are really beneficial for people. You know, as you care for people with some of these issues, one of the things I know you're an expert on, you and I have a similar passion for this, it's gut health. You wrote a best-selling book called Gut Feelings. Is that one of the biggest things you're addressing?
Starting point is 00:09:28 And then how are you addressing people? Here's, I guess, the base of the question is, how are you addressing those issues today? Food, diet, lifestyle. What are some of the things, like if you have a patient come in with pots, or you have a patient come in with some of these different forms of autoimmune illness?
Starting point is 00:09:44 What are some of the ways that you are treating and getting good results right now? I will say this, that you, we kind of reference this, that cases are getting more complicated. They are not as easy as they once were. I mean, 90% of our patients, when they meet us online, they are eating way better than the average American. That's so true. They're not, like, occasionally, again, 10%, maybe, are kind of still eating standard American food, but it's few and far between. I mean, we are seeing people that are the really good. They've honed in their nutrition.
Starting point is 00:10:18 They're doing all the wellness stuff. They're doing all the biohacking stuff. They've read in books, educated themselves on the research or listening to podcasts. And they're better off than they would be if they weren't doing those things. So I'm not saying it's for naught and in vain, but they're like stuck at this plateau. And they're not where they need to be. And so that's a phenomenon that we're seeing more and more of these sort of resistance to interventions, positive therapeutic interventions.
Starting point is 00:10:46 We're used to beyond the basic cases, as I guess what I'm trying to say. And that's who God is bringing us at this point. And, you know, it's a sacred responsibility for us to be of service for them because we know that they're kind of spinning their wheels and they've, at the end of the rope, I've done it all like what's going on. So to answer your question pointedly, I would say we have to start with food, but we have to really dig deeper with the things that are otherwise innocuous, but are causing, they're stressing and already stressed out immune system.
Starting point is 00:11:19 So when you look at elimination diets, and there's many ways to do an elimination diet, but there's foods like vegetables and many plant foods that I, from a clinical nutrition standpoint, you and I would say, yeah, there's lots of benefits to these things. Yeah. But it's not the food's fault, but it's, a destroyed microbiome, a hypervigilant immune system and nervous system where you kind of have to meet the body where it's at and go really gentle. So resources like a GAPS protocol, which it's an acronym that stands for gut and physiology
Starting point is 00:11:52 or gut and psychology syndrome, which involves a lot of soups and stew and broths. And it really just easy to digest foods. Carnivore, carnivore-adjacent, carnivore-ish protocols can be another tool. And being specific about things, when we need to. go there, but lower histamine protocols could be helpful, which some of those protocols easily modifiable. And none of these foods are inherently bad. And that's why it's always balancing the science and art of it, because they don't want
Starting point is 00:12:21 to create this sort of orthorexic overcorrection of people fearing otherwise real foods. I don't think it's the food's fault. But it's the price for paying for the destruction of the human microbiome, which is intimately connected to that soil microbiome that we talked about earlier with the environment. So, yeah, that's the initial food approach is for me to take and assess how resilient is this person's system. And sometimes we really have to pare it down to give the body sort of a proverbial siesta, like a break, a Sabbath to just be like, I'm going to focus on repairing and not being stressed out about these otherwise not stressful things. supplementation we want to see what's causing the hyperreaction because remember for people out there inflammation is not inherently bad all these issues that we're talking about are inflammatory
Starting point is 00:13:15 we have to ask the question what's causing the inflammation so that's what I talked about within gut feelings is dealing with both the gut and the feelings the physiological symbolic of the gut and the feelings the mental emotional spiritual side of things so to look at what are the things that are causing that bucket to overflow. So it's looking at foods, then it's looking at environmental toxins, it's a massive thing. I think when we deal with environmental toxins
Starting point is 00:13:41 and then also the mental, emotional, spiritual toxins, if you will, will a lot of food sensitivities actually go away. So back to my early point is, I don't think it's the food that's the issue. It's like when you're not dealing, when you see someone's, you measure out of a urine test and blood tests,
Starting point is 00:13:58 the body's creating antibodies and glyphosate, herbicide, being secreted from the urine, that's a problem. That's going to irritate the immune system, spiking inflammation. It's going to really mess up the microbiome, which is where 75% of the immune system is. So to address the glyphosate piece, to address the microplastic piece, to address the forever chemical piece is a significant needle mover for us clinically. It's not linear.
Starting point is 00:14:24 It's not, doesn't happen overnight. But to support detoxification in that deeper way is necessary for the body to know it's safe. and it's not being irritated by these otherwise real foods. And then the feeling side is very important too. So dealing with unresolved trauma, dealing with chronic stress to a lent, again, let the body know that it's safe. Let me ask you something in regards to that. Do you think it's a doctor's responsibility, whether it be an MD, a DC, a DO, you know, a primary care practitioner? Do you think they should have some level of being able to address the mind in the emotional and the spiritual component of helping somebody heal?
Starting point is 00:15:08 Absolutely. Yeah. I think that if nothing else, be a clinical quarterback and not gaslight your patient and refer them to someone who has a specialty. But I think we should have enough acumen to speak felt language, enough acumen to not be Googling. enough acumen to not be Googling right in front of them and saying, I think this is what, because this is so, I mean, the research is so clear, the mental, emotional, spiritual side. So I don't think every doctor, primary care physician, specialist needs to be an expert in all this fields, but we at least have to have some knowledge of it
Starting point is 00:15:44 to point them in the right direction. Well, I mean, I absolutely agree. I absolutely agree with you. And I think, again, we could go to the dictionary right now and it's going to say health is health of body, mind, and spirit. I mean, we're, it's, it's all of those areas. And so I do agree that not every physician also has to be a psychologist and pastor, but, but having, again, as you said, the acumen and the ability to, to refer out or give resources to help people mentally and spiritually, because anybody that has been in practice, like you and I've been in practice, when I see patients, just as much as his food is making
Starting point is 00:16:19 them sick. Yeah. relationship issues, lack of spiritual and divine wisdom or connection, those things together are making people sick just as much as food, or more. Yeah, without a doubt. And to look at both sides of that coin, one of the things I have telehealth patients fill out is it ACE score, adverse childhood events or experiences. And it looks at things like, I mean, heavy stuff, like sexual trauma growing up, physical
Starting point is 00:16:50 abuse growing up, neglect growing up, substance abuse growing up. I see so many people will gaslight themselves because they'll look at other people and say, well, it's not that bad. It's not that bad. It's not the event as much as the response to the event. And back to bio-individuality, a central part
Starting point is 00:17:08 of what we do in functional medicine. Some people have different genetic variants, HLA, methylation, detox, that their buckets already kind of smaller. You have like these sort of traumas over the cumulative over your life on top of the physiological stuff like we're talking about with environmental factors that something's got to give so yeah for some people the mental emotional spiritual side is a significant
Starting point is 00:17:31 piece of the puzzle for some people it's a smaller piece of the puzzle but to ignore it is doing your health a great disservice because i see the people that are consistent with that side of things the feelings side of gut feelings they move the needle so much more significant so true because you're you're supporting that parasympathetic because the vagal tone is so weak in so many of us, right? That resting digesting. So anything you can do to support vaguely tone.
Starting point is 00:17:59 You know, I don't think a lot of people realize as you're talking about vegal tone, this is this parasympathetic rest and digest response that it's almost impossible for your body to heal, even if you're eating the perfect foods, the perfect foods for you, if you're staying in that fight or flight mode, it's the opposite
Starting point is 00:18:15 of healing. Your body, if you're, when your body's an optimal healing state, it's resting, it's digesting, it's regenerating, versus if you're in a fight or flight state, it's just protecting, it's not regenerating, it's not healing, it's not, I mean, not even close to that parasympathetic state. And so that as physician seems like that is one of the number one things we should do. And I think that I see doctors all the time violate the Hippocratic Oath,
Starting point is 00:18:43 and I bring this up a lot, but I think I see them violate it constantly because the Hippocratic Oath is first do no harm. most doctors, the first thing they do is if a patient goes and sees them is they put them in a state of fear or hopelessness. And it should be the exact opposite. And so really they're putting them in a state to where it's going to interfere with their healing. Oh, absolutely. I mean, it's the mindset. I mean, you've written a book about this, which, by the way, I got up at 3.30 in the morning to be here with you today.
Starting point is 00:19:11 And I walked into the bookstore at the airport and I saw, I think this, not that at the airport. Nice. That's great. And I was going to sign it for you. but I didn't. Wow. Hey. Hey, I didn't do it.
Starting point is 00:19:22 Yeah, you're absolutely right. I mean, what we eat for breakfast, lunch, at dinner matters, but what are we serving our head and our heart on a daily basis? And those are the things that are more nebulous. They're more non-prescriptive, because it's more straightforward for us to say, like, okay, from a clinical nutrition standpoint,
Starting point is 00:19:39 talking about macros and micronutrients and superfoods and all the exciting science around botanicals and herbs. But it is a lot. more gray and non-linear to say talk about stress and trauma. Like you can't just say don't have that drama. Stop stressing. Then they stress about not stressing. So I think there's a, these are more complex conversations to have, but they're things and I would say our Western mind, especially a lot of, I think people that are interested in health and wellness historically. There are people that like the prescriptive stuff. Just tell me what to do. This isn't as easy to say,
Starting point is 00:20:17 we'll just do that because that's a big that's a lot of to unpack over time. Yeah. And our Western mind likes the black and the white and not the gray. This is a lot of gray for people and it could be hiding underneath the surface. That's we've trained our nervous system to be a certain way since childhood. And it takes work to retrain it. Yeah. I mean, there are like I know for myself probably the biggest thing I've struggled with is striving. Like feeling that if I'm not doing something all the time, you know, and some of this may go back to me feeling like I
Starting point is 00:20:47 need to prove myself or feeling like, you know, again, that's what gives me some worth is like accomplishing things. And so I think for some people, it could be that. It could also, again, trying to meet the approval of others, you know, people pleasing. And so there's a lot of these things that we literally have to go and do work. And it could be with the Bible, could be with a counselor. It could be a lot of its good habits, right, getting in these good habits on a regular basis. Do you have anything in particular that you've struggled with feelings, gut feelings, emotion-wise? And are there any practices that you have where you are, where there's a form of this sort of spiritual medicine that you're feeding yourself in order to optimize your spiritual
Starting point is 00:21:31 and mental health? Yeah, I mean, lots. I'm prone to anxiety. I definitely have to keep myself in check. So these are, I call them in the book and I talk to patients about having these metaphysical meals, like treating these mind-body things like you would a meal. And for us, like every day without fail for the past 15 years, like most of my telehealth team's remote, but there's a core of seven, eight of us at the like HQ. And I, every day for the past 15, 16 years at this point. We start our day off with devotion and prayer. And as a team, when we go over the schedule for the day and we pray for the people that are on the schedule. Wow. I love it. And so it's good, it's good for us, but it's also good for us to just be, our prayer in the morning is how can we be
Starting point is 00:22:24 channels for these people? How can we be channels for your healing God in these people's lives? Because we know they're going through heavy things. So that's something that's something that. helps my anxiety, something that I feel like I need to have it all figured out, or I need to have all the answers, that I need to, I'm in control of it all, but realizing and surrendering every morning to say, no, I'm not in control. I'm not the generator of productivity and success in somebody's life or in the clinic's life. But how can I just be a channel for healing in people's lives? It's so powerful. I know I've done a similar thing where When I've taken care of patients where it's like,
Starting point is 00:23:06 there's something so valuable in praying for somebody. You know, I think that I told my staff this recently, I said, most people that come into a clinical practice, brick and mortar, or that visit a virtual practice like you and I have, most of them have never been told for maybe a whole week, I love you or I'm proud of you or you can do this. Or I mean, so many people today are not being nourished. spiritually, emotionally like you're sharing.
Starting point is 00:23:38 And so for being able to do that as practitioners is one of the first and foremost things that, you know, I think all physicians should really focus on doing is bring hope, bring healing, bring love in order to help people. You know, I know this is something, again, you've talked about in your books. I know this is something as you shared you're doing such a good job of. I want to switch gears a little bit and talk about metabolic health. This is something else. You've talked a lot about gut health.
Starting point is 00:23:58 Actually, I want to say one other thing. You know, I think that I read a study recently that went through sort of how, And this is different than maybe was previously thought, but there's anywhere from probably 50 to 100 trillion bacteria living or gut and digestive systems. Most people's microbiomes are not healthy. Are there any interesting statistics or anything that you've seen when it comes to? How many people today do you think are struggling with some sort of digestive health, leaky, got something to do with the digestive system? And when you look at, this is how I would probably answer that, because there's no studies to show, I think, specifically, I would love that study done, a specifically leaky gut syndrome, right, increased intestinal probability. If there is a study out there, let me know about it.
Starting point is 00:24:46 But what I would say is when you look at the study, when you look at 93% of the population having a metabolic problem, 50 million Americans having autoimmune disease, you look at the mental health epidemic, you look at the infertility epidemic, what do all those things have in common in the scientific literature? Leaky gut syndrome is a component to it. So it's at least a piece of the puzzle. Every single one of those. And some researchers would say it's causative. It's a precondition for a lot of those issues, meaning that you have to have these other issues. I would say probably something a little bit more moderate
Starting point is 00:25:20 and saying it's at least a component to it. And so I would, with that knowledge, it's virtually every human being is somewhere on that gut dysfunction spectrum. whether it's mild. And this isn't to scare people. Look, the flip side of that real quick is that, to repeat myself, all of these things are healable, overcomboable, supportable. So this isn't to be doomsday. But this is just to say, look, we have to, it's like Maya Angelou, that quote from Maya Angelou, when you know better, you do better. So I'm saying that just to say, oh, yeah,
Starting point is 00:25:56 oh, now I know this is why I feel the way that I do. Let's do something about it. Because the body's amazingly resilient. Yeah. So it's a massive amount of people, but we know more about it than ever because of the exciting science that's within the space of gut health. And at the end of the day, like you've talked about for so long, research is catching up with ancient medicine. Yeah.
Starting point is 00:26:20 Yeah. This is nothing new to traditional Chinese medicine, Ayuravetic medicine, indigenous medicines around the world. Yeah. You know, one of the things I've started recommending patients is very high-dose probiotics, up to like a trillion a day. And that's probably 20 times the dose that most people might take in a probiotic supplement. But I think the reality is, is that if you've got 100 trillion bacteria in your gut, taking one trillion, isn't that crazy? Especially if you've been put on an antibiotic drug.
Starting point is 00:26:47 I think most people today, that's one of the biggest issues. A lot of people are probiotic deficient. I think a lot of people today are not getting a lot of those soothing and nourishing herbs and foods in their diet that I know that we both recommend so often. And then, stress. We know that really is impactful and can be damaging on the gut microbiome. But there's a couple things, hormones I want you to talk about here. And one is cortisol and the other is insulin. When I think about the two hormones that tend to then impact estrogen, testosterone, thyroid hormones, all these other hormones in the body, it tends to be insulin and cortisol. Is that something you would agree with? And what are some strategies you have for patients to help them start getting both
Starting point is 00:27:24 cortisol and insulin under control? Yeah. So without a doubt, we have a, insulin, a rise of insulin resistance. That's really one of that hallmark issues with that 90% of people that I'm talking about is they have insulin resistance. So if you look at what I'm meaning there, we're made up of cells. On every cell of our body, we have insulin receptor site. Think of receptor sites for people out there. Receptor sites are, I think of them like baseball myths.
Starting point is 00:27:52 They're kind of signaling aspects of the cell that's supposed to catch that baseball or that hormone to turn on or turn off some sort of pathway. And insulin's job is to, in part, many other things, but to get glucose or blood sugar into the cell for energy, to create ATP. And many people have insulin resistance so that receptor site that baseball mitt isn't as optimal, maybe like a tattered baseball mitt.
Starting point is 00:28:20 It's not doing its job very well. So there's hyperinsulinemia. And you can measure this on the blood. You do serum insulin fasting, a lot of people, the majority of people, are going to have higher serum insulin than we want for optimal. And it doesn't mean that they're all egregiously high, but they're going to be higher. What are some of the side effects of that? If somebody has higher insulin than they should.
Starting point is 00:28:41 Well, it's a fat storing hormone. So it's definitely, it can make it more difficult to lose weight. You can look more puffy than you want to or could be significant weight loss resistance and obesity and all the things we're seeing around the world. The brain is rich with these receptor sites, so a lot of brain fog, fatigue. can be driven by insulin resistance. And because the body's interconnected, it is going to throw off a lot of other hormones
Starting point is 00:29:05 or a cascade of different issues. And we mentioned PCOS or polycystic ovarian syndrome. That is an insulin resistant issue. And all the confluence of different variables here will be contributing factors to the rise of infertility in the world. So, yeah, those are some of the main things that insulin resistance can drive.
Starting point is 00:29:29 And then cortisol's oftentimes directly proportional trying to attenuate this situation. Because cortisol is not inherently bad. I mean, God made insulin, God made cortisol. It's just subject to the Goldilocks principle, right? Not too high, not too low, but just right. It's homeostasis.
Starting point is 00:29:48 So cortisol, it's a stress hormone, but it's also an endogenous immunosuppressant. So it's a natural anti-inflammatory. So if cortisol is high, it's not happening randomly in a vacuum. So it's typically a hyper-inflammatory state that the body's saying, okay, yes, this is stressful. Yes, that's pump out this anti-inflammatory cortisol to get it down. So I don't see, like the way that we see the body, we don't see cortisol as inherently bad. But it's certainly going to create more problems because it's an unsustainable situation.
Starting point is 00:30:21 You're pumping your body full of stress hormones throughout the day, a dysregulation of that HPA axis, the neuroendocrine axis. It is just unsustainable. So it creates that autonomic nervous system issue of the sympathetic fight or flight, freeze, fawn response is overactive in that resting, digesting, that parasympathetic, that vagus nerve that we talked about earlier. That is one of the other reasons why we have such poor vaguely tone, poor gut health is because of these feedback loops communication line. So we have to deal with what's stressing out the body. What are some of your top prescriptions? Let's do these in a separate bucket for. Let's start with insulin and let's go to cortisol.
Starting point is 00:31:00 And I do want to mention for everyone listening, I mean, insulin resistance, even if it's mild, I mean, it's associated with so many conditions, right? I mean, we know PCHOS. We know Alzheimer's disease. I mean, there are a lot of medical conditions there that could benefit from this advice. So what are some of your top prescriptions? Could be food, supplements, lifestyle stuff for supporting insulin. Yeah, so supporting blood sugar balance, supporting insulin, you could start with food if you wanted to. I mean, looking at your macronutrients, looking at proteins, fats, and carbs, and looking not in an obsessive way, not in an orthorexic way, but just knowing how you're fueling your body.
Starting point is 00:31:39 So getting at least the very minimum, 100 grams of high quality whole food, all the essential amino acids, protein throughout the day. And you would know that by tracking in a food tracking app. Not for it ever and ever. I don't think most people, it's beneficial to be that granular about that stuff. But I want you to at least be educated and inform. Almost use the food tracking for a week or so as a mindfulness practice in education to learn, oh, yeah, this is what 100 grams of protein even looks like. And then be in the ballpark at the minimum of that every day.
Starting point is 00:32:14 Because why? that increase that impacts insulin and leptin and grelin signaling so your satiety signaling is going to be modulated in a way that's going to support you feeling full or longer it's going to be short you're going to have more stable blood sugar throughout the day and it's also the amino acids are raw materials for a lot of neurotransmitters and hormones and the building muscle i mean your muscles like lean muscle mass is like a blood sugar sponge and the more lean muscle you have the more where your body can take in so it's not circulating in the blood. So protein is paramount. Healthy fat to satiety is also an important part and your cell membranes need it. Your immune system needs it. Your brain needs it. So things like avocados, olives, white, hot fish, grass-fed beef and not fearing fat.
Starting point is 00:33:03 And then fiber-rich carbohydrates, you know, fruits, vegetables to digestive tolerance. As I kind of started off the differentiation with, you have to meet your gut where it's at. So some of me throwing out different foods, if you're having digestive issues with it, look, you have to kind of pare things down. But fiber does support bacterial diversity, which is good for the microbiome. Yeah. And it blocks any glucose or sugar from passing to bloodstream. So it stabilizes blood sugar when you increase fiber to digestive tolerance.
Starting point is 00:33:34 So from a nutrition food standpoint, that's where I would start. And then obviously there's so many like herbs, botanicals that we could talk about as well. Yeah, numerous. How about cortisol? What are you some of your top prescriptions there? Well, all that stuff, the more you can create blood sugar stability, the more you can support gut health, you're lowering inflammation levels. Yeah, cortisol is naturally going to come down.
Starting point is 00:33:55 So I think that largely that's going to be, you're going to see a cascade of good neuroendocrine or a nervous system hormonal communication line balance. You and I both have an infinity for adaptogens. So I think adaptogens are something to bring those in in, you know, teas or powders or capsules. These are foods. Well, what are some of your favorite adaptogens you prescribe and that you also take yourself? I love holy basil or Tulsi, which has been used in Ayurvedic medicine for a long time. I love ashriganda.
Starting point is 00:34:32 I love rodeola. I love functional mushrooms as well. Yeah. So like Chaga and Lions, Maine, Rashi. So I'm not saying everybody needs to get all of those things, but the great convenient blessing of the time that we live in is that a lot of these superfoods come and blends. That's right.
Starting point is 00:34:48 So you can get them in one scoop. You can get a good dosing of all of these things. Or get the single ingredients and cook with them or make a tea out of them as another option as well. Yeah, I love it. One of the things that has Rosen in popularity the last 10 years is a carnivore diet or a lion diet. You know, we've got people that I admire greatly like Michaela Peterson, Jordan Peterson, we know Paul's
Starting point is 00:35:09 Saladino, this is for a time. They're following a carnivore or even an all red meat diet. What are your thoughts on that diet? I utilize it clinically when we need to. I don't see it as a long-term lifestyle. I see it as a clinical nutrition intervention as an ultimate elimination diet. And I've talked to all of those people you mentioned over the years, even when Paul was like strict carnivore, that was my advice. I was like, that's how I use it. And he's loosened up over the years. Oh, he's added in fruit and honey and milk. Paul, you come to my side of things. But like, and that's okay. And he's doing great. Yeah. I mean, it's all, listen, my diet now is different than what it was 15 years ago. I mean, we're, yeah. And many people, like, someone like Paul,
Starting point is 00:35:57 who's a wonderful human being, it's like, it worked for him for a time. And he was talking about things because it was his experience of these foods, as they talked about at the top of the conversation, otherwise fine foods, but we're creating stress on an already stressed out system. So I think as he healed his body, he could do reintroduction. That's right. And long-term, lower carb, ketogenic, which you've talked about, I've talked about for a long time. Yes, these are interventions you should use for a season of your life as you need to as medicine. but there's going to come a time in your life with what served you in one season
Starting point is 00:36:32 you don't need to always do. So it's okay to pivot. It's okay to evolve. You're not a failure, not a fraud. Like I said, that quote from Maya Angelou when you know better, you do better. And it's okay to say, well, yes, this did serve me for a time,
Starting point is 00:36:46 but I don't necessarily always have to do it. And I think sometimes people within the wellness world, they have their one thing and they apply it to everybody. That's right. And it's like, if somebody has a hammer and everything's a nail, that's, yeah, that's all they do. And if someone looks at patience all day long and not just looking at academia or looking at your own self, but you're looking at all the people in the world.
Starting point is 00:37:10 That's very different. It's hard to be so dogmatic. That's true. Because you're just like, yeah, if I hung my house one thing, I'd be proven wrong all day long. That's so true. Yeah. It's so true. You know, is there anything that concerns you about or reason you'd be concerned about somebody doing carnivore long term?
Starting point is 00:37:27 From a nutrient, strict carnivore, yeah, there's a lot of problems with that because, and long term is so relative because people could definitely do it for years. It's true. Yeah. And they'll need to because what has taken years to get to where they're at, they're going to have to really rehab their immune system in their gut for a longer time. So if a lot of plant compounds, plant proteins, plant fibers, plant sugars are causing reactions in these people, you have to do rehab on that.
Starting point is 00:37:57 person's gut. But I would say for the average person that's really has a dysregulated system, we're talking about weeks, months more commonly, and then we work on reintroduction. The reintroduction is just as important. If we're improving resilience, the body shouldn't be stressed out about fruits and, you know, juices and, you know, vegetables. And the proper preparation of some of these foods matters. Like, are we cooking them down, making them more digestible, puraying them sometimes in soups and stews? So there's a lot of ways. It's not. just black or white. It's like, well, how are we preparing this food that makes it more digestible? Yeah. And I think for a lot of people, the way that they'd go about doing this, and if you're a person on
Starting point is 00:38:36 carnivore, and let me say this, I had a great conversation with Dr. James D. Nick Lentoneo. And he's great. And he started getting into, because he's done a lot of research on this, and he said his concern that he's seeing in the medical literature is, is that, and by the way, this is something that people talked about years ago, acidity versus alkalinity. And most of the time, it was probably blown up and not necessarily the biggest problem. But his point is that it does put the body in a state of acidity, where he believes he's seeing research where it's starting to pull minerals, alkaline minerals out of the bones and out of different areas of the body,
Starting point is 00:39:09 and that's going to harm the bones, possibly the kidneys and other organs over time. And so we're not even talking about after one year. It might be 10 years, but long term, very long term on these diets as an idea. So we want to start reintroducing some foods. And, you know, in Chinese medicine, And it would probably be something like, you're introducing baby food. I mean, that's what they'd have you do. You know, so it's like ultra-steamed green beans and carrots or probably even before that
Starting point is 00:39:35 would be something like pears, you know, baked pears. Yeah, I have make people, yeah, they do like make sort of a compost. They'll, like, cook down pears or berries and make sort of an inside of a pie without the pie part, without the crest part. Yeah. Yeah, so that's how meticulous some people have to be. Now, some people, when they've got to enough resilience, they can bring in fresh fruit and be fine. But we're talking about very sensitive, reactive systems.
Starting point is 00:40:02 And because of the environmental and the sort of chronic stress trauma piece, we're seeing this critical mass of something's got to give. And we have to be having the compote conversations because that's where the person's gut health is. because you're breaking down those plant proteins, the plant fibers and the plant sugars, making it more digestible. So, yeah, that's, so there's, another thing that I think of in addition to what you said about the alkalinity is the impact of these lower carb long-term protocols, which carnivore would be that, ketogenic diet would be that, is the impact on the thyroid hormones and female sex hormones. Those are another
Starting point is 00:40:47 reason why I see them dipping on labs and we're getting diminishing returns. Whereas like for a time that ketogenic or that carnivore, strict carnivore diet served them, they're getting way more good out of it than any potential drawback. But they're kind of, okay, then you see
Starting point is 00:41:03 the thyroid hormones are taking a dip. Their T3 conversion, T4 to T3 conversions taking a dip. So what can we do for reintroduction? Because what's good for the gut isn't necessarily great for the hormones long term. And you have to balance that out. And that's the science and the art of all this and making judgment calls when you're navigating it from a case standpoint. Or if the person's
Starting point is 00:41:25 doing it on their own, just consider these variables when you're looking at the food you're eating. I mean, you know, we're living in a world today where when we think of even nutrition or medicine, it's thought about as a science. But there's almost a sort of artistic sometimes like trying to really mold and, you know, work with somebody in that way. And that's why. I think when most people go into their doctor's office, it's like, you know, we've heard the analogy of like it's like hurting cattle. It's like you're in, they might look at the intake form
Starting point is 00:41:53 for five seconds, prescribe you a synthroid or an antibiotic or statin and say, antidepressin and say, I'll see you later. I mean, that's what the type of care most people are getting today. It's robotic. Versus the thing I think you and I both realize, and I think about with my mom with this,
Starting point is 00:42:06 my mom had cancer, my mom needed more than that. My mom needed more than just, we need to put you on chemo and then tamoxifen and then, you know, see and get mammograms. every little bit. But for my mom, what helped her heal and reverse and her cancer was it was an art.
Starting point is 00:42:23 It was love. It was me walking her through. Here's exactly what to eat. Hey, let's try. Does this work with you? Does this not work with you? It was much more relational. If you've been doing everything right,
Starting point is 00:42:35 eating clean, exercising, but somehow you're still not feeling your best, your energy's dragging, your memory is slipping, and it's frustrating because you know there's more to your potential? Well, what if the issue isn't just in your routine, but it's deep down inside your cells? You know, you're investing in the best supplements working out regularly and sticking to a clean diet, but if your cells are stuck in what's called cell danger response,
Starting point is 00:43:03 all the hard work might not be paying off as it should. Think of your cells like a house under renovation. You can bring in the highest quality materials like the best supplements in clean foods, but if the workers inside the house or are on lockdown because of a storm, nothing gets done. The material is just pile up unused. That's what happens when your cells are in CDR. They can't fully use the good stuff you're giving them. Getting out of CDR, the cell danger response, is the key to unlocking your body's full potential. When your cells are no longer in protective mode, they can finally use the nutrients, hormones, and energy you're working so hard to provide. That's when everything starts to click. Your energy improves. Your workouts become more
Starting point is 00:43:52 efficient and you start to feel like yourself again. Go to BeyondBloatwork.com to learn how to break free from cell danger response and make the effort pay off. Autism One conference? Yeah, with Jenny McCart. Yeah, that was such a great event. Like 2017. She's been such a great spokesperson for the autistic community, her son. Obviously, I was on the spectrum and she helped him so much with that. I remember years ago when her and Jim Carrey went on, I think it was the Larry King show.
Starting point is 00:44:27 Yes. And I remember watching it live in person. And then after I remember just the backlash and then everyone trying to act like they were crazy. But I think today most people would look at this and say, you know what? There are issues with the amount of shots people are getting. There are issues with antibiotics. There are issues with our food and all the chemicals we're giving to our kids today. So I think now people are way more open than they were before.
Starting point is 00:44:49 And similar thing, I think with RFK, I think there were so many doubters and people that are trying to discredit him over the years. But one thing I'll tell you, and I think you probably think the same way I do about him. I respect him so much. The number one reason is he just loves kids. Like he truly, he's not in this for the money. He truly wants to help make autism non-existent. He truly wants to help kids get healthy. So that's first and foremost something I've just respected about him so much.
Starting point is 00:45:20 Yeah. What are your feelings on RFK? I know you've met him a few times, got to speak with him. Yeah. Yeah. He's a great guy. As far as I know, being around him, the few times that I've been around him and talking with him, he seems like an authentic human being, way more than most people in D.C.
Starting point is 00:45:37 Yeah. So I think that we agree. that's the thing. You don't have to agree with someone across the board. I'm not even saying, I agree with him on his major issues of looking at the chronic disease epidemic. How could you disagree with that? Looking at the censorship and the surveillance industrial complex in this country, which is so connected to what our work is within health because our patients are medically gaslit and then they can't even share their experiences in social media without fear of they either will self-censor themselves knowing that they'll get, they'll get shut down or they get censored for just talking about their own experiences with autoimmunity and their health. Or sharing information they learned. Just free exchange of information. So that's important to him. And I mean, not health-wise, but talking about the Forever Wars.
Starting point is 00:46:27 These are all important things for America. And even if you talk about Forever Wars in the realm of health, the research around PTSD, I see a lot of that with research with patients. and intergenerational trauma. Like you think of what we're doing when we have these unnecessary wars, it's impacting generations to come around the world. So, yeah, the topics that are important to Bobby
Starting point is 00:46:53 are important to me. So there's definitely an overlap, but not just me, most of us within health and wellness. Oh, yeah. Of all different, it's this nonpartisan. I recently spoke at a chiropractic conference called Max Living, this group of, it's an amazing group of doctors.
Starting point is 00:47:06 These doctors are super passionate. Actually, I think I're, remember somebody told me like your dad you know intended a few times yeah yeah back in the day many many years ago and so I got to speak to this group and in every single one of this I mean I'm talking about hundreds of doctors there's probably 300 there and all of them are so excited about what Bobby Kennedy's doing in terms of trying to try to make America healthy again trying to take care of the kids and protect them and not allow these big organizations that are really driven by money alone with nothing else there. Big pharma, big agriculture, big, you know,
Starting point is 00:47:42 some of these big food companies. And so anyways, I'm out to you and I both know so many people that are chiropractors and osteopaths and functional medicine MDs. And across the board, 99% of them from what I've seen are really excited about some of the initiatives that he's focusing on. It's not a person. That's right. I've made a post about this other day. I'm like, whoever gets in in November, these truths will remain. That's right. It's a lot. It's a is a matter of are they going to pay attention to it or not are they going to move the needle in the pause direction or not um so yeah it's just about who actually is paying attention to what we're facing as a society yeah you know one of the things is i went through and and uh through this back
Starting point is 00:48:22 issue um i became so mindful of longevity i mean i i think as i was in bed for a year and was in so much pain and so grateful now to be on the other side of it of he and i look by the way you know You've learned from this too, but going through our own health challenges or having family members go through it, it's a greatest learning experience because it's one thing to be working with somebody else. It's another thing when you yourself are dealing with it. I mean, it's like you're spending thousands of hours learning and you're learning yourself. And I think once you learn it yourself can overcome it, there's a level of sort of mastery that can happen. And so for me, going through this, I realize that I want to do everything I can to be active in feeling good in my 80s and 90s, even more than. before. And longevity
Starting point is 00:49:08 has been something I've become so passionate about. I know you have started a new supplement company, longevity RX. I know this is something that you are really passionate about as well, is longevity. What inspired you to start that company? What has inspired you to want to help people
Starting point is 00:49:23 with longevity? Well, it's really so tied into my telehealth work because all those chronic diseases that we talked about, depending on the study that you site, it's about four to ten years off of our life. The United States spends more on health care than all industrialized nations, yet we have the shortest lifespan and the most chronic disease
Starting point is 00:49:49 of all industrialized nations. So we have to do something different to see something different. So my passion for longevity, i.e. longer, healthier, more vibrant life, like how can you live your best life is really borne out of my telehealth patients and seeing the potential of the human body. And I know, look, I could see patients 10 hours a day and I have seen patients for 10 hours a day for the best 15 years. I am scraping the surface of the amount of people that need our help and need this information. So I think when you're looking at things like people can bring in their own life and maybe don't have access to a functional medicine doctor, or maybe they don't even need a functional medicine doctor right now. What can they do on their own to bring in their life
Starting point is 00:50:36 to start to reclaim their health for the better? And there's so much exciting science around health span. So how can we support health span in an easy, effective way? So that's really where the project was born out of is seeing the plight of people with chronic health issues or people that just want to optimize. They're somewhere on that spectrum of inflammation and they know this brain fog, this fatigue. These are signs of accelerated aging. And they may not have a severe chronic disease, but they know they're not living their best life. These are proverbial check engine lights to say, look, yeah, you're aging faster than you need to. And so many people settle for it, right? Oh, yeah. Because they gaslate themselves or they go to their doctor and they're
Starting point is 00:51:21 told, you know, you're just getting older, just settle for it. That's right. It's your lot in life. No, just because something's common doesn't necessarily make it normal. That's right. Because something's your everyday doesn't mean you should settle for it. And so many people settle for feeling less than they have the capacity to feel. Have you ever done one of those, you know, a biological versus chronological age test, like a glycan age or telomere test or anything like that? Yeah, I have. Yeah, we run it on telehealth patients. It's exciting because every couple years, there's new labs coming out instead of aggregating the data and assessing, you know, what your, your cellular age is, basically.
Starting point is 00:51:59 Were you like 12 or 13 years old? Yeah, it was basically nine months, those nine months, just learning to walk. It's so great. It's so great. But these tests are great. I mean, it's amazing we have technology now to where we can test. And again, if you're, like, I'm 43, it can tell me if I'm got the body of a 33-year-old or a 53-year-old.
Starting point is 00:52:16 I mean, it's really amazing to be able to see that. And I think that's great for patients because then it gives you really, something to strive for. Yeah. Like, I want to get younger. And that's one of the best tests out there, you know. And I think Peter Attia's book, David Sinclair, covers a similar thing. And one of the arguments in some of those books is that almost all disease in a way
Starting point is 00:52:34 is aging. Yeah. You know, because, and there's this great study out of Stanford. I think last time I saw you, we might have just chatted about it for a few minutes. But they went through and basically they created blood markers to not only test your biological age of your whole body, but test. the biological age of different organ systems. So they had like four or five different systems. And so what's the biological age of your heart? Because so many people, and I know this is
Starting point is 00:52:58 something that just breaks my heart. I had my father-in-law pass this year from a heart attack. And it was one of those things where I think about, gosh, he was so healthy in so many areas. I mean, he was on zero medications. We thought he was absolutely fine. But he did. We didn't find this out until pretty much around that time he passed. But it was he had high blood pressure. And he just thought it was white coat syndrome. But I think it was. probably really high for a long time. And if we would have been able to kind of test and gauge, okay, what's your biological age of your heart
Starting point is 00:53:27 or your immune system or your gut or whatever it might be? I think there's just so much, so much value there. Yeah, you're right. And science recognizes around 12 hallmarks of aging, and a lot of them have to do with inflammation. A lot of them have to do. And that's why that sort of coined phrase of inflammation,
Starting point is 00:53:45 it's really an inflammatory component when you look at gut dysbiosis or looking at synonymous, Inescent cells. That are these things that accumulate that are these zombie cells that are, they're impervious to opoptosis. They don't want to die. They ignore cell death and they survive like zombies, releasing all these pro-inflammatory cytokines. So a lot of the longevity and health span research is centered around these inflammatory, these cytokine models of aging, these cytokines are pro-inflammatory cells.
Starting point is 00:54:18 So so much of what we do is modulating inflammation in a way where you're not in this hyperinflammatory state because that's what's aging people. So there's 12 different differentiated aspects of it that we can understand today. But a lot of the commonality is inflammation. Yeah. What are some of your top foods, maybe supplements as well? I know, again, as we talked about, you've created this new supplement company, longevity RX, where you're creating some of the most premier supplements when it comes to longevity, really specializes. By the way, this is something so many more people are interested. There are a lot of people, like they're millennials, people in their 30s, they're saying,
Starting point is 00:54:55 I want to start aging slow now. Like my wife is one of those people. My wife's skincare routine, my wife's supplements. I mean, she takes a lot of supplements to slow the aging process and to not only, you know, one other thing. Sometimes I'll have people say this. They will say, I did this post on Instagram with my top 12 foods for longevity or to live to 100 or 120. And quite a few people commented, I don't want to live to be 100. Oh, yeah. I get
Starting point is 00:55:23 that comment. And so it's not only, listen, here's the thing I just want to say. It's not just about adding years to your life. It's about adding life to your years, which is actually the tagline you have for longevity RX, which I think is so, so great. But my point there is is that a lot of people say that, but here's the thing. If you felt really good and you could still be active running around at 100, No, you would want to live to be 100. Likely, if you felt great, you had a purpose. Again, if the things were lining up with your life. No, you're absolutely right.
Starting point is 00:55:51 For years when I would write about the longevity research, like the most of the science shows this, that most of us can live over 100 disease-free, healthy years. We're not talking about just chronological age. We're talking about health span, not just lifespan. We're looking at both, enhancing health span and enhancing lifespan. So whatever lifespan you have, you're going to have abundant, vibrant life. So, yeah, I'm excited about the science about it.
Starting point is 00:56:22 And you don't need necessarily all the fancy tests to get access to this. And that's why I'm so excited about this line, that people, no matter who you are, can have access to science-backed, effective tools to support cellular health, to support health span. Yeah, what are just a handful of the superfoods or herbs or something, some things you like for supporting longevity? I'm fascinated around a postbiotic that you can, a body can make from pomegranate extract. Wow. So it, postbiotics are basically the, the products of probiotics. So we have prebiotics, probiotics, probiotics, too.
Starting point is 00:57:06 And I think that one specifically is called urolithin A. It supports something called mitophagy, which is mitochondrial atophagy. So if you break that word down, autophagy atophagy, it's self-eating. It's all the healthy cells gobbling up all the dead dysfunctional cells. So it's one of those ways that we can mitigate the 12 hallmarks of aging is supporting mitophagy or mitochondrial health, which is our cellular energy factories. And this postbiotic urolithin A can do that, and we get it from pomegranate extract. So that's one that I'm excited about.
Starting point is 00:57:43 I think supporting NAD levels is also really important because as we age, NAD can drop. So it is needed for cellular energy. And there's so many superfoods and adaptogens that I love that people may not see as supporting longevity, but because they're modulating that stress response, they're lowering that inflammatory state, they're lowering that fight or flight state back to what you'd say. with your father-in-law, I had a similar story with my dad, is when somebody is, when the human body is stuck in that stress state, we may not, we may not even know it. Yeah.
Starting point is 00:58:22 Because on the outside, everything's fine. Yeah. But because we live in this messed up world in many ways, that we need to be supportive of that parasympathetic. So back to some of those earlier things that I mentioned about the adaptogens, I think they can be really congruent to health span as well. Yeah. Yeah.
Starting point is 00:58:39 this compound, I know, as I read up on it, this compound in pomegranates, sometimes it's found in certain raspberries to allegeic acid that then can, if it's fermented, turn into urolithin A. And most people have heard of some people have heard of urerlythine A, but there's also Yorilithin B, C, D, there's all these other urelethins that you, you know, there's a supplement brand out there I know that has just sells a uralithin A product, and that's beneficial. But it's so unique about, I know what you've done with your product is it not only produces uralithin A in the body, it's urelythin B, it's a, you know, it's aulithin B, C, D, and it's probably a way more absorbable form of your Lothanae.
Starting point is 00:59:13 And so I think it's so, so cool. So for everybody out there, and some of my top longevity foods, as Dr. Will talked about, it's foods like pomegranates, it's figs. So it's foods that tend to be that dark black, blue purple color blueberries, blackberries, getting more of those in your diet. As Dr. Will talked about the adaptogenic herbs. He talked about earlier like Oshuaganda, Holy Basel, some of the medicinal mushrooms like cortiseps and rishi.
Starting point is 00:59:35 These are foods that promote longevity, green tea. I mean, we could go. we could do a whole show, and maybe we will here in the future, just do one solo on longevity. But again, it's not just about adding years to your life. It's adding life to your years. And that's something that I know Dr. Will and I feel both very passionate about is helping people live their best life possible, helping people reverse chronic disease, helping people regenerate their organs and tissues and heal at a cellular level and regain their health. Dr. Well, this is fun. I know we're going to get, we're not going to true food kitchen after this.
Starting point is 01:00:04 I'm bringing you to urban market. Yeah. Yeah. One of our... To me, it's the best thing. In Nashville, it's the best restaurant. It's so good. If you're in Nashville, it's in Franklin, Tennessee,
Starting point is 01:00:15 but you might see Dr. Will and I there. We love it. And this has been so good. Thanks. Thank you so much, my friend. We're going to the farm today. We actually got a farm here south of here that we're going to go and pet some water buffalo. Yeah.
Starting point is 01:00:28 And go to our greenhouses. We do regenerative agriculture. We grow actually some of our own superfoods. And I know some of the things that you put in some of your... amazing products. You do are a regenerative agriculture base. So something that we're both excited about. So anyways again, hey, thanks so much for my friend here. Dr. Will Cole, one of the leading functional medicine experts, literally in the entire world, longevity expert as well. And also, by the way, check out his podcast, check out his social
Starting point is 01:00:54 channels at Dr. Will Cole. He has so much great content out there. I want to encourage you guys to check out. I want to say, hey, thanks so much for tuning in here to the Dr. Josh Shack Show where each and every week we're diving deep into the science and principles behind how to grow in body, mind, spirit, and take your health and your life to the next level. Hey, by the way, don't forget to subscribe, share, and like. And if you're watching on YouTube, please comment. We'd love to know what is your biggest takeaway from this conversation with Dr. Will Cole today. And by the way, there are so many people suffering. Thank you for all of you that are on mission with us who are sharing this podcast. We believe that this is going to bring hope and healing
Starting point is 01:01:32 and health to make America healthy again. Thanks so much for watching. I'll see you on the next episode.

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