The Dr. Josh Axe Show - How Peptides and Bioregulators Heal the Brain, Liver, and Heart

Starting point is 00:00:00 Believe it or not, your organs can literally get younger, not with surgery or organ transplant, but actually reversing your organs age. And this was discovered some 40 years ago. And there's a whole science behind it using peptide therapy or a specific type of peptides called bioregulators that might actually be able to turn back the clock and make your brain younger, your heart younger, your skin younger, your hormone younger. I mean, can you imagine as a man having double and triple the levels of testosterone or as a woman, you are able to fly through menopause, having more balanced levels of progesterone and estrogen and thyroid hormones without taking hormone replacement therapy, drugs, and other sorts of conventional medicine? Well, today I'm going to be talking about these advanced form of peptides called bioregulators,

Starting point is 00:00:52 which are just now creeping into the United States, which I, believe are the future of healing. Welcome to the Dr. Joshak show. Now before I jump in, this is one of the most controversial topics that I will cover. And this tends to get buried when I share things that help people heal naturally and that are not necessarily fully legalized yet. This is a great area. And the platforms I speak on sometimes don't want you to see this video. Oftentimes these sort of topics around this exact podcast get shadow banned. So if you want to make sure you get cut edge episodes like this in the future, make sure you're subscribed. I know many of you are subscribed, but many of you aren't. So if you want to keep up with what's going on, the most

Starting point is 00:01:51 advanced scientific breakthroughs in the world today, whether they're fully legalized or not, make sure to subscribe here to the show. It helps you keep seeing the truth rather than being silenced. All right, let's dive in here. What are bioregulators? Well, bioregulators are very small, naturally occurring protein snippets or types of peptides. They're technically ultra-short chains of amino acids, also known as short peptides that are between two and four peptides in length, and they act as genetic switches turning on and off genes. Now, of course, we know this is important. If you're familiar with breast cancer genes or even things like MTHFR, we have these genes in our body that can be turned on or off, and peptides tend to turn the wrong genes off and turn the right genes on

Starting point is 00:02:44 if you have them in sufficient amounts. And recent medical evidence has shown that they may help restore heart function, brain health, liver function, your immune system, and so much more. In fact, the leading researchers of bi-regulators, Dr. Kavanaugh, along with other scientists, have demonstrated that these peptides can extend the lifespan of mice by up to four. 40% in some studies. Now, the origin of bioregulators came with this Dr. Kavanaugh, and his research began as a secret project for the Soviet Union's military and government, which wanted to reverse premature aging caused by radiation exposure. And after decades of research, Kavinson developed a range of peptide-based pharmaceuticals and dietary supplements that have been introduced into clinical practice. So this is something,

Starting point is 00:03:37 that has started to grow in areas like Russia and Asia, and now it's making its way into the United States. And as you age, your organs don't just get slower. They can become dysfunctional. And your brain loses speed. Your immune system starts to weaken. Your digestion can become off and your heart becomes less efficient. But you can actually turn back the biological clock by supplying your organs with these peptides, also known as bioregulators. And many of these peptides and bioregulators have started to be used by everything from the cosmonauts to Olympic athletes and professional athletes. But now it's making its way into anti-aging and functional medicine. And I myself have started using these with patients for improving sleep, hormone imbalances, supporting testosterone levels,

Starting point is 00:04:29 supporting patients with hypothyroidism, helping people overcome chronic pain issues, chronic fatigue syndrome, a number of benefits we see around peptide therapy. And these specific peptides are called bioregulators. And you can get some peptides and bioregulators in the injection form or even in capsules. And of course, also straight from real foods, especially Oregon meats, which I'll get into, is where you'll find many of these as well. Now, I do also want to mention why this happens to be a great area with peptide therapy because pharmaceutical companies are wanting to get their hands on things so they can make these

Starting point is 00:05:06 things for pennies and charge you a lot of money. And unfortunately, that's the reality. I mean, the crazy part is these bioregulators are found naturally occurring in organs and glands, okay? But what we're able to do is take those compounds and do them in higher doses to where if somebody has, for instance, a weakened immune system, we can do these thymus gland peptides in higher doses, and it does tremendous things for boosting the immune system. Well, of course, pharmaceutical companies are spending all of this money on. lawyers trying to create patents around certain peptides so you have to pay a large amount of money from. The other thing it does is they actually will have to go through some regulation.

Starting point is 00:05:48 So if the pharmaceutical companies have their way, you wouldn't even have access to these peptides for another 10 plus years. And that's why it's such a gray area right now in peptides, certain peptides aren't fully legalized, even though a lot of people, you can go to many functional medicine or cellular medicine clinics and you can get peptide therapy today, it is not fully legalized. Only reason being is pharmaceutical companies are trying to patent these drugs. Here's an example. Certain types of peptide therapy we know are more popular than ever like semi-glutide, GLP 1, like Ozympic and Manjaro.

Starting point is 00:06:26 And of course, those are mainstream. Why? Because pharmaceutical companies have their hands on them and are now making billions of dollars. off of these types of peptides. But the reality is, again, these are more like supplements than they are medications. Again, they're peptides. You know, I obviously started a company many years ago where we were the number one or two selling brand of collagen, collagen peptides, right?

Starting point is 00:06:51 Collagen's a peptide. Where is that coming from? It's coming from the ligaments and the tendons, not necessarily an organ per se. It really actually could be considered a type of organ if you consider your muscles and your connective tissue organs. but you're getting loads of peptides from that, right? So we consume peptides. Anytime you're drinking bone broth,

Starting point is 00:07:10 anytime you're taking a collagen peptide supplement, you are getting peptides. And those are type of peptides that are very good for your ligaments, joints, and your connective tissue. But there are other peptides that are great for your thyroid hormones, that are great for your immune system, that are great for your brain. And what peptides tend to do is they help improve communication.

Starting point is 00:07:33 within your body. Now, I am grateful we have Robert F. Kennedy, Jr., in office because he is aware of this, and he is fighting and trying to legalize peptides fully. And here is actually one of his only quotes where he is referencing peptides, and here's what he says on a post on X. He says, the FDA's war on public health is about to end. This includes its aggressive suppression of psychedelics, peptides, stem cells, Raw milk, hyperbaric therapies, chelated compounds, ivermectic, hydroxychloroquine, vitamins,

Starting point is 00:08:10 clean foods, sunshine, exercise, nutraceuticals, and anything else that advances human health and can't be patented by pharma or pharmaceutical companies. This was an exact quote by Robert F. Kennedy Jr. And what RFK Jr. is talking about is obviously not conspiracy theory. This is just pharmaceutical companies are saying, hey, we see this being the next billion dollar industry. we want our hands on it and we want to control who gets it and be able to mark it up to make a lot of money. We see Robert F. Kennedy Jr., as we talked about, he's been referencing peptide therapy and bioregulators. We see Joe Rogan.

Starting point is 00:08:47 He had a nagging elbow issue with tendinitis, and he said it vanished within two weeks of using BPC 157. So we see Robert F. Kennedy Jr. using these. We see Joe Rogan using these. I've got numerous friends like Ben Greenfield. and Will Cole and many others that are using them themselves. Neuroscientist Andrew Huberman claimed two injections resolved his L5 spinal pain, a condition that normally takes months to heal. We've seen numerous athletes using this.

Starting point is 00:09:17 One in particular had a major hamstring tear and recovered much, much faster than he should have because of using peptide therapy. So bioregulators and peptides, they don't replace hormones or directly provide your body with nutrients. instead they travel to specific organs, bind to the DNA in the nucleus, and turn on repair and regeneration genes. Okay. So for instance, you know, I myself experienced this when I had a life-threatening infection. I was bedridden for a year, couldn't walk, and had so much inflammation pain and tissue

Starting point is 00:09:55 damage because the infection around my L5 vertebra, in fact, the infection went from my disc into my full bone, the entire bone was infected, and an abscess around my spinal cord. And I had a lot of damage there. And I had a doctor tell me that I may be permanently disabled, I would likely be permanently disabled. I would likely be permanently disabled. I would have chronic pain every day because the damage would be so bad, and they would likely have to fuse my spine because the degeneration. Well, I got turned on to two things, stem cell therapy, and peptide therapy. And I started doing a fairly high dosage of BPC-157, TB-500, and GHK-C-U. This is a peptide blend.

Starting point is 00:10:33 I was doing it subcutaneously daily. And after six weeks of doing it, I was blown away at my pain reduction. And the thing that was so amazing was it's not like I had pain, it went away, and then it came back. No, I had pain, it went away, and just kept getting better. I mean, that's what was so amazing in terms of just the improvement I saw in a short period of time. And the reason that worked was these different types of peptides went into different organs in my body. They started turning things on saying, we've got to take our healing and regeneration up a notch. Okay. And as you get older, your body isn't as good. It loses some of its

Starting point is 00:11:13 capabilities of repairing and regenerating. I mean, the amazing thing is, is our bodies are continually healing and regenerating. I mean, every seven years, almost 100% of your body is new. It's at least a 70%, sometimes it's much higher. But for many of you, when you're regenerating is you're not regenerating very well in creating fully new, healthy younger tissues. What peptides do is they improve the communication process and they turn on these genes so you can fully heal. And you might notice this, right?

Starting point is 00:11:41 If you're in your 40s, 50, 60s, you're like, man, when I was 18 years old, I would have an injury. And a week later, I was back playing sports and I felt fine. And I didn't have this long-term damage from it. Well, today you have something happen. It takes two weeks, four weeks. It's constant your tendonitis, whatever it is. And what peptides do is they actually can help you fully regenerate and heal some of those tissues and help optimize their function.

Starting point is 00:12:08 Now, they do many other things outside of just tissue regeneration. And I'm going to touch on a few of those things right now. But there are over 20 identified bioregulators. and each organ has its own, by the way. So the thymus clan has bioregulators, your thyroid, your testes, your ovaries. They have biore regulators. And they've been shown to restore circadian rhythms. In fact, one in particular epitalin is great at this.

Starting point is 00:12:34 A reverse aging of certain immune organs. Improved brain function and memory. Regenerate the liver in kidney tissues. Normalize blood pressure and cholesterol. Lengthen telomeres. strengthen mitochondrial function and so much more. Think of peptide bioregulators as your body's original software. They're coded to reboot cellular function at the level of your DNA,

Starting point is 00:13:02 helping you rebuild your body and promote healing. Now, again, I've referenced both of these things, peptides and then the shorter chain bioregulators. Peptides tend to be longer chains of amino acids that often act like hormones. They are signaling molecules that bind your receptors and trigger, specific effects like BPC 157 for the gut and in tissue repair. That's actually there's there's proof of this out of the international journal of molecular science. So several medical journals have already proven the benefits of BPC 157 for tissue regeneration. Another peptide CJC 1295 or

Starting point is 00:13:37 Ippamorlands another one. These have been shown to help increase more human growth hormone. And then there's thymus and alpha one. That comes from the thymus gland. That's been shown to boost immunity and tamp down autoimmune reactions and reduce inflammation. Again, what bioregulators are, they're much shorter, usually two to four amino acids long. By the way, you might be familiar with with shorter peptides like creatine. Did you know that's a tripeptide? It's actually three different peptide, three amino acids connected together. So creatine is a type of peptide. It's a tripeptide, so it's glutathione. And so these are things we know. know scientifically that have major, major benefits. I mean, think about all the benefits of

Starting point is 00:14:21 creatine and glutathion. Those are those shorter, three-stranded amino acids that are very similar to bioregulators. They turn genes on or off. They don't act like drugs. They restore normal function. By the way, here's what drugs do. They force your body to do something oftentimes it doesn't want to do. I'm going to force your blood pressure down. I'm going to force your cholesterol down, right? That's what drugs do. what bioregulators do and peptides and vitamins and minerals is they give your body what it needs in order to function at the highest level possible they might increase communication that might give you a building block it might optimize a detoxification pathway that's what peptides and vitamins and minerals do drugs force your body to do something and so bioregulators what they do in essence is restore normal function now standard peptides work

Starting point is 00:15:17 through cell surface receptors, whereas bioregulators cross the gut barrier, penetrate the blood brain barrier, and enter the cell nuclei directly. So that's the big difference. So you're not going to have peptides because they're longer. They're not going to go through the blood brain barrier and the gut barrier often cases. What bioregulators will do because they're so small is they will pass through and they actually enter into the cell in a lot of cases. The key difference is this. Peptides stimulate, bioregulators normalize. Are you interested in functional nutrition tips to burn fat, reduce inflammation, improve your brain and energy levels, and heal naturally?

Starting point is 00:15:59 Then I want to encourage you to listen to my friend Dr. Dave Jocker's podcast, the Functional Nutrition Podcast. This podcast is designed to help you with easy, actual steps to improve your nutrition and lifestyle, understand your lab work, and address the root cause factors that may be driving up inflammation in your body. Now, I've been friends with Dr. David Jockers for 20 years, and he's truly a world expert in functional nutrition, cellular healing, and so much more. If you want to learn the best nutrition and natural healing tips, tune in to the Dr. Jockers' functional nutrition podcast on Apple, iTunes, Spotify, YouTube, and wherever you can listen to podcasts worldwide. Hephides, or specifically bioregulators, follow an ancient Chinese medicine principle, and it's called this, like, Heels Like.

Starting point is 00:16:46 organs and glands when you consume them help heal other organs and glands. Now, we also know this extends into Chinese medicine with certain foods. For instance, like supports like. When you look at a beet, you cut it open. It looks like it's bleeding. That has nitric oxide that supports the blood, right? Carrots look like your eyes. Salary looks like your bones.

Starting point is 00:17:07 Rishi mushrooms look like your adrenal glands and kidneys. And so they support those organs. Walnut looks like a hemisphere of your brain. It supports the brain. well, this is the principle bioregulators function in is it's like supports like. If you take a bioregulator for the thyroid, it is going to improve your thyroid function. If you're taking a bioregulator for your liver, it's going to support your liver function. That is what happens because what bioregulators are when Dr. Cavinson was doing research, he said,

Starting point is 00:17:40 okay, well, what are the peptides found in thymus gland or in the thyroid? Okay, I'm going to discover and look at those thyroid peptides. I'm going to study those peptides in the thyroid and create thyroid peptides that can be now taken as a supplement. And so I want to say this, if you want to get bioregulators and peptides in their most natural state, consume a lot more organs and glands. Like one of the supplements I take regularly is not just liver, which I do a lot of liver, but I do organ and gland supplements a lot. I mean, that is your greatest natural source of bioregulators.

Starting point is 00:18:16 As part of a natural cancer therapy or immunotherapy, when people had weakened immune systems, they would take thymus gland and also sometimes multiple other glands that support your immune system, like the spleen and other glanulars. When they were going to detox, of course, we know the original Gershon therapy had you juice a lot of vegetables and actually juice calf liver or eat raw beef liver. okay and so why because he was trying to support the liver and detoxification channels and like supports like so we had them eat a lot of liver but there are specific peptides and bioregulators in those organs and glands that you can benefit from but for many of you you need a higher dosage of what than what you're going to get in a food to experience the greatest level of healing and so you're just going to get a more

Starting point is 00:19:06 concentrated dose which is really what all supplements are right here's an example when you eat an orange, an orange might have 60 milligrams of vitamin C. Okay. If you're taking a thousand milligram dose, right, that's of course, that's like eating, you know, probably, you know, close to 15 oranges. That's a lot of oranges, right? To get up to that, that dosage. So my point is, is it works like a supplement in that way. It's just a higher dosage and you're going to notice, experience more of a difference. But on a day-to-day basis, I'm doing organs and glanulars. And then if I need some sort of a natural form of medicine, that's where I'm taking key bioregulators. And here are some of the most studied and promising organ-specific peptides and bioregulators you need to know about. First one here is called

Starting point is 00:19:50 thymulin. Okay, this comes from thymus gland. This regulates the immune system, slows aging, and reduces your risk of infections. It's used in cancer support and viral illnesses and recovery. And as I mentioned earlier, this thymulin was sort of the, it was the, it's the main. It's the main peptide or one of the two main peptides in thymus gland that's been used for a very long time for bolstering and strengthening the immune system of patients and so thymulin is one you want to know about especially if you have a weakened immune system of any sort. Maybe it's cancer, maybe it's multiple food sensitivities and allergies, maybe just get sick with a cold and flu more easily than you should. You want to consider taking thymus gland or thymulin as a bioregulator peptide. Also, even

Starting point is 00:20:39 autoimmune disease it's used for as well today. Epitallin. This comes from the pineal gland. This resets your circadian rhythms, boosts melatonin production, increases antioxidant enzyme activity, and lengthens your telomeres in studies epitallin increased telomere length by 33.3% compared to the control group. So again, this is the peptide that helps stimulate and regulate melatonin production so you can get into a deeper state of sleep. And I've actually talked to several people have said they have really been wild. I was talking to a nurse practitioner recently who works at a functional medicine clinic. I was getting a vitamin IV with a friend of mine, Dr. Darshan Shaw.

Starting point is 00:21:23 And he was saying, yeah, I've used epitallin and noticed a tremendous difference in my sleep by taking that bioregulator peptide. In fact, there was a recent case study that reported a remarkable reduction in a patient, biological age from 76 years old to 68 years old after one year of treatment that combined epitalin, CMAX, and TPE with mesenchymal stem cell exosomes. And so again, think about this, you're getting eight years younger biologically, how much better you'd feel, how much healthier your body is. And epitallin was that key bioregulator used in that study. Now, a few others that you want to note. One is called cortexin. Of course, cortexin, part of the cortex of the cortex of the

Starting point is 00:22:08 brain. This supports memory, cognition, and neuroplasticity. It's used post-stroke and used for neurodegenerative disorder. So this is great post-stroke for supporting blood flow to the brain and helping the brain. Another one is called Ventfort. This is for the vascular system. It improves blood flow, oxygen delivery, and cardiovascular repair, and helps normalize blood pressure. So if you don't want to one with high blood pressure, heart disease, or general inflammation of the cardiovascular system, ventforth is an amazing peptide. Here's another one. It's called lividgen. It is the main peptide or a group of peptides that support liver health. This is a bioregulator supports detoxification, bioflow, and liver regeneration in hepatitis or fatty liver patients.

Starting point is 00:22:57 Now, this is good even if you don't have fatty liver or hepatitis, but if you have those conditions, you absolutely should find it and take it. But in addition, it's just great for liver detoxification. And then glandicor. This is adrenal glands. This helps balance cortisol, improve stress resilience, and support energy metabolism, and great for mitochondrial health. And then vladoxin, this is for the spleen. This is a spleen bioregulator, helps with autoimmunity, lymphocyte production, and supporting red blood cell formation. And I want to go just through a few others, and you'll just see this, is that for every organ, for the most part, there is a bioregulator, a short chain peptide that makes sure that that organ functions well.

Starting point is 00:23:40 So for the adrenal gland, you have adrenalogen, okay? For the bones intended, you have collagen peptides. Of course, you're already familiar with those. For the brain, there are many peptides in bioregulators like peneolin, CMAX, sealing, and cerebracillin. Okay, so there are many for the brain. Colostrum, by the way, as a food, deer antler. There's a lot of foods, by the way.

Starting point is 00:24:02 If you want to know foods that are high, organs are the highest. But along with organs, colostrum has peptides, deriantler has peptides, eggshells have peptides, spryelina has peptides. Back to the organs here, for your heart, you can take a peptide called cardiolipin. That is great for heart health. Kidneys, there's kidneyogen, liver, lividgen, as we talked about, there's also glutathione peptides, ovary's ovaries ovarigen. Also for your pineal gland, there's epitalin and penyalin. These are really great, as I mentioned, for circadian rhythms, anti-aging sleep enhancement. And of course, the stomach and duodenum, you're familiar with this one already,

Starting point is 00:24:41 body protective compound, which is what BPC stands for, for BPC 157. And then there's also bioregulators like testotulin for the testes. We talked about thymusin alpha-1, thymulin for the thymusclin. Your bone marrow and thymus gland, there's actually a bioregulator that sort of combines multiple peptides together called stemogen, and then your thyroid gland, thyroid, thyroid, glyphyrgyn, okay? So there's thyroid-specific peptides that support those organs and functionally properly. And so if you are struggling with any condition that is specific to an organ, know that

Starting point is 00:25:18 even if they're not, even if you don't have access now in the very near future, you're going to start having access to these bioregulators that are going to support organ function. And listen, here, here's what I'm working on currently behind the scenes. I am working on some compounds in things that are going to combine that are going to have bioregulators and peptides in a highly absorbable form. So this is something I'm incredibly excited about. And I think for most people, you know, most people don't want to run out and take a medication. And even though it's not quite a medication, it's still not natural, you know, a lot of these,

Starting point is 00:25:52 hormone replacement therapy, you know, if you could avoid it, you want to, right? And listen, I do think there's a time and a place for HR. T, okay? But it shouldn't be the first thing you do. If you are having hormonal issues, low testosterone for men as an example or perimenopausal, menopausal symptoms and women, the first thing you should do is go and change your diet, use herbs and use peptides in order to support that organ functioning. And then if you do everything you can there and lifestyle changes and your hormones are still off, hey, then there's a time to get on a lower dose of something like HRT, but it really should not be the first thing you do.

Starting point is 00:26:29 Because exogenously, when you take it from the outside like that, a hormone, it's different with food and peptides. But when you take a hormone exogenously, your body stops producing it on its own. So you're not maxing out your body's own ability to make it, which is why, like, if a male has low testosterone, what I do is I have them work on deeper sleep, have them do a lot of foods that support testosterone production like Brazil nuts and walnuts and a lot of red meat. I have them take organs and glanulars. I get them on the right levels of zinc and vitamin D.

Starting point is 00:26:59 I'll have them take herbs like panics, ginseng, and maybe deer antler, and then get on the right peptides and bioregulators. And I found, and then lift weights. And I found with most men, because listen, here's the thing, if you're trying to find the shortcut, you're saying yourself, I'm not going to work out. I'm not going to change my diet. Okay, you can go and take the hormone replacement therapy, but the reality is you still have disease brewing in your body.

Starting point is 00:27:25 And you think it's going to promote longevity by taking this hormone replacement therapy. There are other things that are at play that are causing you to be ill and other errors of your body. So my point is when you change your lifestyle, not only is your hormone is going to come back into balance, your entire body is going to get healthier as a result of it. And when you do it the more natural way, you'll feel better, you'll actually be stronger. And I've worked with so many men on getting testosterone levels, those normal levels. And they've seen amazing results without taking testosterone. Not to say that they might not do a lower dose when they get later on in their years and need to.

Starting point is 00:27:58 but honestly, it's sort of like the icing on the cake because they've already done all these other things and they're aging so well. And that's the philosophy and the mindset all of us should have. Now, back to these bioregulators, you know, these regenerative compounds can help you turn back your biological clock. They can help heal your organs. And these are compounds your body recognizes because they're found in your own organs and glands. And if you eat the organs and glands of animals. But today, they are being heavily regulated and even banned. some of them. And if you want to continue to learn more about peptides and bioregulators,

Starting point is 00:28:33 leave a comment and let me know your thoughts on that and send this to a friend who needs to hear it. And also remember, again, this episode will probably get Shadow Band and others where I'm going to hit on these things more in the future. And if you're not subscribed, it will not pop up in your feed. And so, hey, make sure to subscribe. By the way, it's also the number one thing you're going to do to support the show. It allows me to bring on more and more high profile guests here. like we are continuing to do here in the future. And this is how I was able to bring on everyone from like Carrie Underwood to Tim Tebow to or really well-known medical physicians, Marty Makery.

Starting point is 00:29:08 I mean, he has been on the show. He's the head of the, you know, the head of the FDA there as well. So, so, and I'm hoping next year I'm believing we're going to have, we're going to have Gary Breck on again, Dr. Mark Hyman, Robert F. Kennedy, Jr. So we've got some really killer guests coming up. I'm excited for you to hear it first here on the show, the Dr. Josh Jack's show. I want to say, hey, thanks so much for diving deep with me today. Remember, each week we explore how to grow in body, mind, and spirit and take your health

Starting point is 00:29:35 and your life to the next level. Make sure to subscribe, like, and share this podcast again. You know how many people don't know or have never even heard of bioregulators or peptides? There's so many people. And it could be a form of medicine that could completely transform our functional medicine and natural medicine landscape and help save a lot of lives and help a lot of people age well. and live without drugs and surgery. So really excited about that.

Starting point is 00:30:01 Thanks so much for watching, and I'll see you on the next episode.

The Dr. Josh Axe Show - How Peptides and Bioregulators Heal the Brain, Liver, and Heart

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