The Dylan Gemelli Podcast - Episode #138: 7 Things YOU NEED To Know about NAD+ !! The Dylan Gemelli NAD Optimization Protocol POWERED by Jinfiniti!
Episode Date: June 27, 2026Episode #138: 7 Things YOU NEED To Know about NAD+ !! The Dylan Gemelli NAD Optimization Protocol POWERED by Jinfiniti! I have spent the past 6 months in deep study about ALL aspects of NAD+ I...t came to my attention that it was one of the most misunderstood and widely misused molecules in the world! NAD (nicotinamide adenine dinucleotide) is a small but powerful molecule found in every cell in your body. It helps keep your muscles, brain and heart healthy. Without NAD, you wouldn’t be able to turn food into energy, move your muscles or stay alive. While NAD levels drop as you age, making healthy daily choices may help support it. Most people are misled into just taking straight NAD without an understanding that it is too large of a molecule to penetrate your cells and you need a precursor to increase NAD levels. I discuss the way to increase your levels, along with how to know if your levels are actually increasing. My goal in this discussion is help everyone overcome misguided and confusing information, as well as explaining the massive importance and role NAD plays in are longevity, health and wellness. This podcast guides you through circumstances of confusion and helps you to learn every way to get your NAD levels OPTIMIZED! I met Dr. Jin-Xiong She several months ago when I had him on my podcast. During our interview, Dr. She not only taught me every key aspect of NAD information, he provided me one of the very few options for TESTING my NAD levels. My results shocked me showing extremely low levels of NAD. Dr. Jin assured me that it was not of concern and he could have me OPTIMIZED in just 2 short months. My levels went from the low 20's into the 70's following his protocol. TOGETHER, we have created "The Dylan Gemelli NAD Optimization Protocol POWERED by Jinfiniti! I have listed the link below to get optimized today. I am making it my mission to provide everyone with the key areas of health that we are missing and seeking out the very best companies and Drs. to work together with to do my part in helping everyone achieve full health alignment!! DO NOT MISS THIS EPISODE!! ALSO, stay tuned for updates on a LIVE Fireside Chat that Dr. Jin and I will be featured at the The Ultimate Wellness in Miami event September 24-26th at the Faena Forum in South Beach! Today's episode is sponsored by JINFINITI! The Dylan Gemelli NAD optimization protocol powered by JINFINITI: Save 10% site wide with code DYLAN https://www.jinfiniti.com/dylan-gemelli-protocol/?_ef_transaction_id=&oid=4&affid=131 _______________________________________________________________________________ Get the Apollo Neuro for $99 OFF!! USE CODE GEMELLI to save https://apolloneuro.com/gemelli To PURCHASE MITOPURE visit Dylan's landing page and use code DYLAN to save 20% OFF!! https://shop.timeline.com/DYLAN Qualia Life Supplements: Save 50% off PLUS AND ADDITIONAL 15% off with my code DYLAN www.qualialife.com/dylan TRULY Increase Your NAD LEVELS with WONDERFEEL NMN: https://getwonderfeel.com/?utm_source=DylanGemelli&utm_medium=podcast MESCREEN: The world's first and only at home mitochondrial efficiency test Save $100 with CODE DYLAN https://mescreen.com/cart/47561239626013:1?discount=&ref=DYLAN HIRE DYLAN ON THE MINNECT APP HERE: expert.minnect.com/@DylanGemelli Follow Dylan on Instagram, Facebook, Twitter and Tiktok @dylangemelli and PLEASE SUBSCRIBE and leave reviews!! MAKE SURE TO GO TO DYLAN'S YOUTUBE CHANNEL for MORE video content!! https://www.youtube.com/@DylanGemelliBiohacking Email Dylan for booking, collaborations and/or to apply for the Dylan Gemelli Podcast DylanGemelli@gmail.com Visit Dylan's Homepage https://dylangemelli.com
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Today's episode is brought to you by my great friends at Ginfinity.
One thing that I've learned over the years is that the highest performers do not rely on assumptions.
They rely on data.
And that's especially true when it comes to NAD.
Everyone is talking about boosting NAD levels, but very few people actually know where their levels are to begin with,
whether their protocol is working, or how much they even need.
And that's what makes Ginfinity different, which is why I am thrilled to announce that I have teamed up with Jinfinity
to offer the new Dylan Jameli NAD optimization protocol powered by Ginfinity.
This protocol provides you the Ginfinity intracellular NAD test and supplies you with the most
complete and trusted NAD boosting supplement and protocol in existence, along with proper guidance
to ensure that you are optimizing your health, performance, and longevity.
So check out the link in the show notes and start taking control of your health today.
One of the beautiful things about what I do is that I'm
get to interact with people seven days a week. And I'm not even talking about hundreds and thousands
of people. I'm talking at this point in time, millions. It's a true blessing and it's an honor,
but with that comes a great responsibility. I have to be on my game. I have to study. I have to learn.
I have to know facts. And I have to be able to back them up. And I also have to be able to pivot
when I do something wrong and explain new sciences, methods and means that I may have had wrong.
I have to stay on top of everything because so many of you rely upon me for accurate, insightful,
and trustworthy information. Now, one of the things that I see is the most prevalent problem in all
of the world, but especially the health, supplement, physical, neuroside, it's confusion.
When I look at comments, the most common theme and problem that I see is people are simply confused.
and one of the areas that I have seen the highest amount of confusion over the past several years is when it relates to NAD.
The first thing that I want to convey is the importance of NAD.
I have spent quite a significant time now studying NAD, learning about it, trying to become a so-called NAD expert.
That does not come easy because there's a lot of bad information out there.
There's a lot of changing information and a lot of misunderstanding and a lot of misguided information.
that people tend to put out that are trying to sell something that is just not going to work.
Some people understand and know that and some people are just parroting information and trying to make a quick buck
and don't know what they're doing and actually hurting people or just taking money from people.
Now, I get to interview some of the most brilliant people from all over the world.
I was introduced to Doc Jin Zhang Xi.
He owns Gin Finity.
And I was told I was going to be meeting an NAD expert.
So I absolutely had excitement.
Well, once I got to meet him, that excitement went to me being as curious as can be learning so much that I decided, hey, I don't know a fraction of what I think I know. We're going to have to dig pretty deep on this. During our conversation, Dr. Jin explained to me about the importance of getting NAD testing. And I didn't even know there was really an accurate way to test your NAD levels. And I also, even though reading and understanding a lot about NAD, I did not understand the significance of the role that it played in our wellness and our
our longevity and how much it also played in giving us very strong, powerful mitochondria.
And so upon getting the test with Dr. Jin, I was taken aback at how low my levels were.
I felt like I was in very good health, a lot of great blood markers. Unfortunately, my NAD levels
did not reflect that. So what I did was entrusts to him to fix me, to guide me, to help me.
And he promised me that he could get me right in a very short amount of time.
And I believed in him and rightfully so because he had me fixed up in less than three months.
NAD levels in the low 20s all the way up into the 60s, thanks to Dr. Jen.
So what I have done now is worked with him and his company to make what I call the Dylan
Jameli NAD optimization protocol.
And so that's going to be available to everybody because given what I know,
and the power in my voice and messaging,
it's my duty and responsibility to help every one of you.
So what I'm going to do today is cover seven things that you need to know about NAD Plus.
I have spent a lot of time trying to figure out the things that people are struggling with
and the bad information,
and I'm going to give you every single answer that I know you're looking for and lacking today.
Why most of you get zero results and the data-driven reasons that the approach was wrong from the start.
So we're going to cover a lot of ground here, so I'm going to get right into it.
Now, I have been doing this 20 some odd years in the health and fitness and wellness industry,
and I have tried to study it all, learn it all, and cover every single base I can.
But there's always going to be areas where I'm lacking and need help.
And that's why I go to the expert of experts in any sort of angle and way that I can to learn every aspect.
and I interview people of different mindsets and beliefs on things
and try to extrapolate everything that I can.
What I have found is NAD Plus is one of the most important molecules
that I have ever encountered in all the years of my work.
The science is undeniable.
But here's what I've seen play out over and over.
Most people are using it just completely wrong.
And here's what I wish that more people knew
before spending any bit of money that they work so hard for.
most people are taking the wrong dose.
This is the single biggest reason
while people fail when they use NAD Plus.
And this sometimes doesn't even have to do anything
with the product quality.
You can have the best quality in the world
and misuse it and not get any sort of result
or a negative result.
So let's talk about that first.
One of the most common things that I'm running into
and that I hear is that I took NAD for several months
or I tried three different brands and I'm not getting any sort of results.
None of them did a thing for me.
Or the one that really gets me is spending months on a protocol
with absolutely zero ways to verify that it's actually working.
So one of the most common themes that I see is dosing blindly.
Look, NAD plus absorption is not a one-size-fits-all type of thing.
All right?
Two people can take the exact same supplement at the exact same dose
and get thoroughly different results.
I've seen this play out repeatedly in the research
and in my own experimentation.
Here's an example.
My wife, for instance,
I give her a normal kind of standard dose
in that 900 to 1,000 milligram range.
She feels terrible.
Doesn't feel right, feels off, headaches,
lower it to 500.
Not only did we see results in her blood work
and her testing, but she feels great on it.
Me, I take 1,000 and feel phenomenal.
So everybody's different
and things are trial and error.
Now, understand that absorption,
it depends on a couple things here,
your genetics, your gut microbiome health,
and most critically,
your current intracellular NAD plus level.
So without knowing where you're starting,
essentially you're flying blind.
So one of the things that I've struggled with for so many years,
and I just, sometimes I just want to facepalm,
is that people that don't get testing,
they don't get a baseline,
How can you ever know if something's working for you or not working for you or potentially
hurting you if you don't have a baseline?
So you have to start testing with a number.
Okay, you have to get a baseline number.
Without that, we really don't have any honest answer as to whether something's working or
not working and or hurting you.
So you have to test your intracellular NAD levels before you start.
Get a dose that's calibrated to your actual biology.
not the label average or standard, and retest at the month free time frame to confirm that it actually
worked or not, because at three months in, you should start to see some difference.
Now, let's talk about NAD plus versus NMN versus NR versus NICEN and what actually matters.
Because the supplement industry is just a marketing war.
And I've been in this trench for so long.
I'm going to give you the straightforward breakdown.
All of these precursors can raise your NAD plus levels,
but the variable that matters isn't which form.
It's whether the dose is right for your body.
Pick one, stay consistent, test before and after,
and that's the whole protocol.
So let's start from the top.
And this is where a lot of people have made big mistakes.
Pure NAD plus, it's too large of a molecule
to survive oral digestion intact.
It's not effective as a standalone, and a lot of labels will imply that it is, but it's not.
It's too large to get itself into your cell.
It does not penetrate, and far too many people don't understand that.
This is my favorite and the one that I believe is the very best, and that is NMN.
Nicotinamide mononucleotide.
It's fast-acting, it's well-researched, it's more expensive, but it's more effective for most people,
and it's got the best ability to penetrate into your cells.
Then there's NR nicotinamide riboside.
It's more affordable, but it's slightly slower to build.
And that actually has to convert to NMN to then work.
So why do we, why not you skip that step?
That's my view.
It's still effective if you're consistent,
but you've got to give it the time that it needs.
And then we've got niacin, which is vitamin B3.
That's the original precursor.
It's the most affordable.
But I have had a lot of people.
have bad, bad experiences with it.
Not to mention the skin flushing, which can be quite uncomfortable.
That signals absorption, but there's other concerns that I've seen there.
I've seen elevated liver problems, kidney problems, so you have to be aware of that.
You need to pick one form and stay consistent with it.
Test before, test after.
If your levels don't rise adequately, then you've got to adjust your dose.
Now, does it actually help you with energy and brain fog?
From a cellular health standpoint, sure, but not the way that stimulants work,
and you have to be able to distinguish the difference.
This is one of my favorite topics because the mechanism is exactly what you'd expect
when you understand cellular bioenergetics.
NAD plus does not mask fatigue.
It addresses one of your root causes of it at the mitochondrial level.
So let's look at it like this.
We've got caffeine and we've got stimulants.
So you can generally expect a spike and then a crash.
It blocks adenosine receptor, so it borrows energy from later.
NAD plus fuels mitochondrial ATP production directly,
so you're getting clean, sustained energy and you have no debt.
So here's the honest timeline that I have observed in the research and in my own experience.
Week one, I would have this expectation of minimal but noticeable change,
foundational cellular replenishment is happening.
So don't quit here.
This is where most people make their mistake.
Week two and three,
then you can start to see sleep quality improve.
The afternoon energy drop starts to fade, recovery between sessions accelerates,
and you've got subtle but measurable differences if you're tracking it.
And then week four and beyond,
you'll start to see consistent clean energy,
sharper mental clarity,
the kind of baseline shift that you notice
when it's gone, not when it arrives.
Other benefits that I've seen consistently,
faster workout recovery, improved mood regulation,
reduced joint stiffness, better skin, stronger nails.
These show up differently depending on where you were depleted to begin with.
That's another thing that you have to keep in mind.
Now let's get into the nitty-gritty here.
Pills versus injections versus IVs,
because this is one of the most common questions that I get.
more expensive does not necessarily mean more effective.
The data backs this up and I have looked at all of it.
And I spent a lot of time sitting with Dr. Jin going over this.
I've spent countless hours talking with him,
learning, going over data,
and then researching on my own from what he gave me.
Injections and IDs deliver NAD plus to your bloodstream,
but that's not the goal.
The goal is intracellular NAD plus.
Those are thoroughly different things.
I have data from over 100,000, yes, 100,000's intercellular tests,
and it shows well-dosed oral supplementation,
outperforms injectables for most longevity and performance goals.
So let's take a look at this.
I'm going to give you like a cost breakdown, the delivery, and my verdict on everything.
So first method oral supplements, I would expect between like a $70 to $150 cost there.
Delivery is intracellular, best for longevity and daily performance.
This is the best value, the best way.
Injections, you're looking at a minimum of maybe 200 a month, but more like 500.
Delivery is bloodstream only, and it's really niche use cases on what I've seen.
ID drips, you're looking at 400 to probably about 1,000 a month, which is, again, bloodstream only,
and it's extremely hard to justify on the data that we've been given.
Then I want to look at is NAD plus safe for the long term?
From a research standpoint, yes it is.
Here's what the science actually shows.
I only recommend things that I've vetted in the literature and tested on myself.
And NAD plus precursors have one of the stronger long-term safety profiles in the supplement space that I've ever seen.
You're not introducing a foreign compound.
You're restoring a molecule that your body naturally produces and that it depends on.
Decades of pre-clinical and clinical research support.
favorable safety outcomes. So no serious adverse effects of typical supplementation doses,
which I have found to be 500 to 1,000 milligrams. Some people need a little more,
depending on the severity of the condition. Why you may have felt nothing. I'll tell you,
four errors that I see show up here. So let's say someone spends, I don't know, 60 days on a protocol,
fills nothing, then they stop. They think it's not working. Dosing blindly is number one. Label,
dose is a manufacturer starting point, not a dose that's actually calibrated to your needs and
necessities in your biology. So without a baseline test, like I said, you have no idea if you needed
supplementation to even start with and then how much. Number two, people pick the wrong form for
their biology. Different precursors are metabolized differently. And that depends on gut microbiome
composition. Without testing, you cannot know which form your body converts efficiently. You're making
a pretty significant investment on guesswork. I don't advise it. People quit way too early.
NAD plus replenishment is cellular. It's not symptomatic. The shift is quiet. Sleep improves. The 3 p.m.
crash fades. Recovery accelerates. Quitting at week two is stopping a protocol right before it even
starts delivering. And number four, they had no way to verify that it was working. Without before an
after testing, you have no idea. Feeling better is not data. Feeling nothing doesn't mean it failed.
The only way to know is to measure, which is the entire premise of what biohacking and health even is.
So here comes the fun part, the Dylan Jameli special, what most companies don't want you to know.
And I've talked about things like this at length in the past. And like I said, I'm not going to
ever name drop anybody, but I am going to tell you things that I see and observe so that you
know things to look for and then you can draw your own conclusions on who may or may not be doing
this i've written about supplement industry practices for years and this is the one that really
really bothers me the most the research on nad plus is real the decline with age real the cellular
energy connection real but the leap from nad plus is important to our specific supplement at the
specific dose will raise your levels is where most companies quietly stop providing evidence.
So I want to take a look at some problems here and fill you in on what I see.
The incentive problem.
Well, testing creates accountability.
If a company built testing into their protocol, you'd know whether their product raised your
levels or not.
If you didn't, you'd stop buying.
So instead, they cite research that's very general.
not conducted on their specific product and count on you, not noticing the difference.
Here's what an evidence-based NAD Plus protocol actually looks like.
You test your baseline first.
Intracellular NAD, not a symptom checklist.
You get clinical grade formulations, verified purity, not off-the-shelf bulk ingredients,
retest at the start of month three, objective data shows what actually changed,
and four, iterate until it works.
Adjust your dose or your formulation based on results,
not marketing promises.
And this is the standard that I apply to everything
that I recommend to my community.
Ginfinity is the only NAD plus company
that I found that actually operates this way,
building testing and accountability into the core product.
That, my friends, is why I teamed up with them
and why I specifically went to them and said,
I want my own protocol.
I want you to back me on this.
I have a mission.
I'm very, very, very mission driven and oriented.
And this particular mission is to write the wrongs.
It's to address every single issue out there,
whether it's people wronging you,
companies wronging you,
or your own misunderstanding and confusion
on how to actually go about this.
I want people to see exactly how to do this properly
to be able to see real life,
data and to be able to find an answer to said problem, which is low NAD levels and misguided
information and being taken advantage of. I'm going to fix every aspect of this that I possibly can.
My voice has weight and it has power, but it goes unheard if it's not delivered properly
and if it's not delivered with credibility, accountability, and love for everyone.
That's also one of the reasons why I teamed with Infinity
because Dr. Jen shares the same mission that I do.
Make a massive difference.
Give everybody we can the opportunity to do this.
And so, my friends, the Dylan Jameli NAD optimization protocol,
here's what your testing is going to look like.
I'm going to leave a link for you to sign up for this.
I have specials.
Dr. Jin and I have tried to make this as affordable
and as extensive as we can to really, really, really change your health and your life.
So take everything that I said to heart because all of these things have been happening.
I've done the research and I have done everything in my power to make sure that you get the best
in all you do with health and wellness and also financially.
So that being said, stay tuned for plenty more to come.
Dylan Jameli powered by Ginfinity.
off.
