The Dylan Gemelli Podcast - Episode #145: The WOLVERINE Stack Explained! The stack that started it all... BPC-157 and TB-500! The ORIGINAL Ultimate Healing Peptide Stack

Episode Date: July 18, 2026

Episode #145:  The WOLVERINE Stack Explained!  The stack that started it all... BPC-157 and TB-500!  The ORIGINAL Ultimate Healing Peptide Stack   As many of you know by now, I discovered peptides... in 2011, when there were less than 10 to choose from.  I have watched them grow into having thousands of options for every type of need and condition out there.  The stack that started the "peptide craze" quickly became known as the "Wolverine Stack" because of it's ability to provide rapid and REAL healing as opposed to simply offering temporary relief (band-aiding the wound)  It drew comparison to the well known Marvel character, Wolverine, who had the power or regenerating himself from ANY injury or wound.  While these two amazing peptides do not have the ability to heal bullet wounds, they have worked wonders to help rapidly increase recovery times, healing capabilities and have even shown to have other benefits, including gut health, which is one of the most prevalent problem areas in ALL of health we see today.  I cover the bases in this breakdown, explaining fact from fiction and why this stack holds massive importance for the future of injury treatment and recovery!     I ALWAYS tell you what you need to hear, not just what you want to hear... I am built on facts and credibility, without the exaggerative nature or an attempt for "click bait."   There are things that I convey which may go against the grain of "influencers" who parrot information without actual hands on knowledge or observance of thousands of people and/or fear mongering extremists who have something negative to say every day upon waking... My delivery is about truth, facts and hands on experience!!  ENJOY THE EPISODE!      Today's episode is sponsored by JINFINTI!    The Dylan Gemelli NAD optimization protocol powered by JINFINITI:     Save 15% site wide with code DYLAN   https://www.jinfiniti.com/dylan-gemelli-protocol/?_ef_transaction_id=&oid=4&affid=131         _____________________________________________________________________________   JUST THRIVE HEALTH Use my link below and receive 90 DAYS OF FREE Digestive Bitters when you sign up for 90 days of the Probiotic!!! https://justthrivehealth.com/DYLAN   ______________________________________________________________________________   To PURCHASE MITOPURE visit Dylan's landing page and use code DYLAN to save 20% OFF!!   https://shop.timeline.com/DYLAN   ________________________________________________________________________________________     The worlds FIRST EVER Topical Glutathione at AURO WELLNESS!  SAVE 15% with code "DYLAN" https://aurowellness.com/dylangemelli _______________________________________________________________________________________________     Get the Apollo Neuro for $99 OFF!! USE CODE GEMELLI to save https://apolloneuro.com/gemelli   _______________________________________________________________________________________________   Qualia Life Supplements:  Save 50% off PLUS AND ADDITIONAL 15% off with my code DYLAN   www.qualialife.com/dylan   ___________________________________________________________________________________________   TRULY Increase Your NAD LEVELS with WONDERFEEL NMN: https://getwonderfeel.com/?utm_source=DylanGemelli&utm_medium=podcast                       Follow Dylan on Instagram, Facebook, Twitter and Tiktok @dylangemelli and PLEASE SUBSCRIBE and leave reviews!!           MAKE SURE TO GO TO DYLAN'S YOUTUBE CHANNEL for MORE video content!!    https://www.youtube.com/@DylanGemelliBiohacking       Email Dylan for booking, collaborations and/or to apply for the Dylan Gemelli Podcast DylanGemelli@gmail.com     Visit Dylan's Homepage https://dylangemelli.com

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Starting point is 00:00:16 Today's episode is brought to you by my great friends at Ginfinity. One thing that I've learned over the years is that the highest performers do not rely on assumptions. They rely on data. And that's especially true when it comes to NAD. Everyone is talking about boosting NAD levels, but very few people actually know where their levels are to begin with, whether their protocol is working, or how much they even need.
Starting point is 00:00:40 And that's what makes Ginfinity different, which is why I am thrilled to announce that I have teamed up with Ginfinity to offer the new Dylan Jameli NAD optimization protocol powered by Ginfinity. This protocol provides you the Ginfinity intracellular NAD test and supplies you with the most complete and trusted NAD boosting supplement and protocol in existence, along with proper guidance to ensure that you are optimizing your health, performance, and longevity. So check out the link in the show notes and start taking control of your health today. This holds up in bigger studies, this could be a game changer, a real life-changing moment. The goal here is very simple.
Starting point is 00:01:20 Help your body heal faster. These are probably falling under the category of miracle drugs in a sense. The most talked about peptide stack since ever? The most widely known, used, tested amongst everybody out there. I know we don't have the human studies, but we do have the human studies if we're looking at real world experience. You guys know me by now, you know that I will call out nonsense, things that are blown out of proportion. I'm going to tell you straight up. This stack, it lives up to the hype.
Starting point is 00:01:49 It absolutely does. The problem is like anything else, when something's great or does something extremely well, it's like people start telling tall tales about them. And then it becomes this big marketing fest and everybody parroting information and misinformation gets out there. People will start to tell you that it'll bring people back from the dead at this point. I'm just kidding. But in all seriousness, things do get crazy when something does amazing things. And I want to go through and explain exactly what the stack is, why it's even called the Wolverine stack, and if it may be something you might want to look at. So Wolverine, if you're not familiar, and I'm sure most of you are, if you watch Marvel Comics, Wolverine is the character that's able to regenerate. So anytime he gets
Starting point is 00:02:31 shot, beaten, stabbed, he just heals. So, you know, I'm not saying that that's going to happen, but these are probably falling under the category of miracle drugs in a sense because of their ability to enhance healing and recovery. And they work quite well. There are years and years and years of people reporting this. I've seen it. I've used them. I've coached it. Now, the studies are limited. They're going to be more on the rat study side of things, but there are years and years and years and years of proven benefit. Now, the argument when it comes to studies is the years that we need to see about potential side effects long and short term. Well, we have enough now to see short-term types of side effects and or lack thereof. And there are a few concerns there, but for the most part,
Starting point is 00:03:14 it's proven to be quite safe and effective to use both of these. But that's something I'm going to leave towards a different type of discussion altogether. I'm just going to break this stack down right now. I'll give you an explanation of what it is, how it works and what to expect from it. It's one of, if not the most, talked about peptide combos. Now we've evolved to the glow and the clothes stack, but these are the two backbones, the originators of that said stack. So the goal here is very simple. Help your body heal faster. People originally used it for sports injuries, post-surgery recovery, but now more people are asking whether that they could help with chronic pain, the kind of six rounds for months and years. And so I'm going to get into all of this and see
Starting point is 00:03:54 where we're going. As I mentioned, people use this combo in the hopes that it's going to speed up recovery. I'm talking about muscle tears, tendon injuries, sprains, surgeries. But some doctors, are looking at it now as to whether or not it's going to help with long-lasting pain, chronic conditions, bad knees, joints, inflammatory conditions. Now, BPC 157 stands for body protection compound 157. It's just a small protein that's made in a lab, but it's actually based on a natural protein that's found in your stomach. Once again, we're going to look at animal studies, but it's shown to help tendons and ligaments heal faster. It's showing to grow new blood vessels and hurt areas, calm down inflammation and protect the stomach lining. Unfortunately, the study aspect shows everything on rats and mice for the most part, but like I said, I have years and years of seeing this and seeing the real true effects that people have had. You can look all over online to see the reports. Doctors, now practitioners that run clinics, they use them and they prescribe them. I don't know about how legal or illegal. That's a different conversation as well. Point being, these have been used for so many years now. Now, what is TB 500? TB 500 is a last
Starting point is 00:05:01 made version of part of a natural protein that's called fymusin beta 4. Now what it does is it helps your body repair damaged tissue. Once again, animal research is shown to help healing cells actually move to injured areas faster. So that's supporting new blood vessel growth and reducing scar tissue. Here's one of the differences. TB 500 is shown to work throughout your whole body, not just one spot. So some research out there also suggest that it might help protect nerves which could matter for certain types of chronic pain. So with BPC 157, we're looking at enhancing tendon and ligament healing, stimulating angiogenesis, like I said, new blood vessel growth, modulating nitric oxide levels, improve joint mobility, and accelerated tissue regeneration. TB 500, that's going to accelerate muscle
Starting point is 00:05:50 repair, promote cell migration, reduce scarring, enhance your overall recovery rate, and reduce inflammation. We run them together for very specific reasons. BPC generally works more at a local level right where the injury is. TB is moving throughout your entire body. So people that use this, rightfully so, believe that using them together covers far more ground than either one of them alone. Now let's talk about surgery recovery. So the most common theme that I've seen on why people use these is for recovery from surgery. They want to bounce back faster and rightfully so. Now, animal studies again, but a lot of human, we'll call it research that I've seen. BPC has helped repair tendons, get them stronger, and TB 500 has then reduced the scar tissue
Starting point is 00:06:35 because that can limit your movement after an operation. People that have rotator cuffs, ACL reconstructions, joint replacements, obviously those are long-term injuries. So people are certainly intrigued by the chance to rapidly recover. Not everybody heals the same. Some injuries are worse than others, but I've seen it all. And I have witnessed it. I've talked to plenty of people that have implemented these on their patients. Now, let's talk about chronic pain because this is a little bit different.
Starting point is 00:07:03 Chronic pain is not the same as sharp pain you feel right after an injury. Chronic pain lingers for months, sometimes years. And that's generally because of ongoing inflammation, nerve changes, tissues that never actually heal. Millions of people deal with it. Anybody that's trained a lot, we have those kind of problems, whether really, really minor or actually quite massive and then they just compound we run on them we lift on them we push them and they just get worse and worse and worse we take things to mask them we get cortisone shots we never actually heal now research is still pretty early on this but there's some small human studies out there that are
Starting point is 00:07:41 showing that bpc 157 might actually help with certain chronic conditions let's talk about a few chronic knee pain was one of the ones that i found there was one small study out there it was like 1516 patients with ongoing knee pain that got BPC 157 injections right near their knee joint. And they did a six month and a 12 month checkup. I believe it was 14 out of 16 or 14 out of 15. So that's roughly, what, 85, 90% said that their pain was much, much better. Now look, study was small, no comparison group, but the fact remained that the relief lasted many, many, many months ongoing.
Starting point is 00:08:18 This is not masking of the wound or anything like that. We're talking about real healing, and that's what I care about. Bladder pain, surprisingly, was another one that I was able to uncover. This was in 2024. It was actually quite recent. Twelve women with bladder pain, they had already tried to FDA-approved drugs. Did not work. Shock.
Starting point is 00:08:36 You know what I'm saying. After one BPC-157 injection into the bladder, 10 of the 12 said their symptoms went away completely. The other two said about 80, 85 percent improved no side effects, and some patients felt better within two weeks. I am definitely opposed to opioids, painkillers, anything that blocks pain and doesn't actually heal. BPC and TB 500 are a totally different approach,
Starting point is 00:09:02 and this is one of the reasons why I love them so much. These are actually healing people. They're not just bandating a wound. So we're trying to repair damaged tissue. We're trying to fix inflammation. These are the things that caused the pain in the first place. So if this holds up in bigger studies, man, this could be a game changer, a real life-changing moment that we could be on the brink of.
Starting point is 00:09:23 What I'd like to do now is just take a quick look at the dosing protocols. These are pretty general across the board. There's always people that are an exception to the rule, but pretty much these are pretty standard dosing. General profiles of both of these that are well tolerated, I have rarely seen any sort of side effects whatsoever. Sometimes depending on if you have a bad product, bad injection, not being sanitary, you might see some injection site reactions,
Starting point is 00:09:46 some pain, some redness. And with BPC 157, I have read a few reports of mild GI discomfort, very, very rare. And, you know, I have read a few of lightheadedness and flushing with TB 500, but I kind of relate that more so to people that probably just have a fear of needles that get that way because it's very, very rarely reported. So with TB 500, that's generally just 2 to 5 milligrams per week, and that is split into two injections. With BPC 157, it's 250 to 500 micrograms per day, or with oral capsules, it's a twice daily dosage.
Starting point is 00:10:23 Now, then that poses the question, what if you're buying a blend? I'm not the biggest fan of a blend. I never have been in anything. When I discussed a lot of things on anabolic steroids, I was never a fan of blends. I'm not a big fan of blends on peptides either. I think that it's always better to just take them one by one. If you have a blend, it would depend on the number and ratio,
Starting point is 00:10:43 of what's in there for any sort of real recommendation on that. I kind of like to leave that alone because it's not something I generally recommend. I believe that you should just take them one at a time. There's very few human studies. So when we're looking at safety, that it's something that you just tread lightly. I always tell people don't try to go overdoing things. A little bit goes a long way. Less is more.
Starting point is 00:11:04 So more things that I've seen are what if questions. For instance, one of the what if questions, peptides that help cells grow and build new blood vessels. In theory, these could feed hidden cancers. That hasn't been shown or with anybody using these, but it's also potential. And if you have a history of cancer, autoimmune disease, pregnant or breastfeeding, I would probably stay away from them, just precautionary. But these are kind of more what-if questions.
Starting point is 00:11:32 I don't see really any sort of other side effects. There's just like I said, site reactions that people, you know, could have with anything. So just be aware and never try to do too much. Okay. As you can see, synergistically, these are amazing to work together. You're trying to speed up healing from injuries. You're trying to speed up surgery healing, chronic pain, joints, inflammatory conditions. I am a big, huge advocate of both of these. I love KPV. You've watched my videos. You know KPV is my number one and all B. So when you talk about the stacking and we get into that Clow stack, which I'm going to discuss later. That's BPC 157, TB 500, KPV, and GHKCU, Copper
Starting point is 00:12:16 Peptide. That is, to me, the ultimate, ultimate stack for healing and multitudes of other benefits in there that we'll get into at a later time. We're just talking about these two. If you want to keep it very small and you just want to run two and not go too far, then these two are just phenomenal. I want to tell you one more quick difference between these and opioids. Opioids just block pain signals. That's it. So just keep that in mind. BPC 157 and TB 500 aim to repair damaged tissue and reduce inflammation at the source.
Starting point is 00:12:51 A lot different than blocking a signal. You can't take opioids forever and they're only going to block signals. And then what happens? You're actually working on an injury and making it worse because you don't feel the pain. Kind of like with a cortisone shot. I did that a few times myself and I've always advised other people to not do it. And then I went ahead and did it, just made my injury worse, and didn't take my own advice. So just be wise and look for real healing.
Starting point is 00:13:16 You know, opioids too, they can obviously cause addiction. They can cause a lot of people to suffer in multitudes of ways. Oh, and lastly, when it comes to running these cycles, I generally go around eight weeks on a BPC TB 500 cycle. I've gone up to 12, but I always am a fan of rest, taking time away from compounds, not overdoing it, letting your body get a chance then to just kind of go back to homeostasis and not have too many things going on at once. So remember, less is more. This is a marathon, not a sprint. Don't go crazy. Don't go overdoing it. Use these things with respect and caution. And that goes for anything that you do. So I hope that everybody finds this helpful, enlightening, and also know, you know me. I keep it as real as you
Starting point is 00:14:01 can. And this one certainly gets an A plus grade for me. So that being said, stay too for plenty of to come Dylan Jameli, signing off.

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