The Dylan Gemelli Podcast - Episode #21: Dylan Gemelli gives a short and sweet explanation of the well known peptide Ipamorelin

Episode Date: April 27, 2025

Do you want to learn the details of the Peptide Ipamorelin?? Peptide Expert Dylan Gemelli give a very short and sweet explanation on what it is, how it works, how to use it, what to expect, the possible side effects and more!   Follow Dylan on Instagram, Facebook, Twitter and Tiktok @dylangemelli Huge thank you to everyone for the support! Please make sure to subscribe, like and comment!!   Today's episode is sponsored by Apollo Neuro!   Get the Apollo Neuro for $90 OFF!! USE CODE GEMELLI to save https://apolloneuro.com/gemelli _______________________________________________________________________________ To PURCHASE MITOPURE visit Dylan's landing page and use code DYLAN to save 20% OFF!! https://shop.timeline.com/DYLAN     TONUM supplements for the MIND AND BODY!   USE CODE "DYLAN" to save!!  https://www.tonum.com/DYLAN     THE BREAKTHROUGH MIMIO HEALTH FASTING MIMETIC SUPPLEMENT!  20% OFF with code Gemelli  https://mimiohealth.sjv.io/c/6588260/3323599/30611     TRULY Increase Your NAD LEVELS with WONDERFEEL NMN: https://getwonderfeel.com/?utm_source=DylanGemelli&utm_medium=podcast     MESCREEN: The world's first and only at home mitochondrial efficiency test Save $100 with CODE   DYLAN   https://mescreen.com/cart/47561239626013:1?discount=&ref=DYLAN       HIRE DYLAN ON THE MINNECT APP HERE: expert.minnect.com/@DylanGemelli     Follow Dylan on Instagram, Facebook, Twitter and Tiktok @dylangemelli and PLEASE SUBSCRIBE and leave reviews!!   MAKE SURE TO GO TO DYLAN'S YOUTUBE CHANNEL for MORE video content!!    https://www.youtube.com/@DylanGemelliBiohacking Email Dylan for booking, collaborations and/or to apply for the Dylan Gemelli Podcast [e-mail] Visit Dylan's Homepage https://dylangemelli.com

Today's episode is sponsored by Apollo Neuro. Apollo is the leading doctor recommended wearable technology. Apollo's award-winning smart vibes AI works effortlessly behind the scenes, automatically integrating into your life to deliver gentle, personalized vibrations that activate your vagus nerve, helping you fall asleep faster, stay asleep longer, and wake up balanced, focused, and ready each day. Not only that, but the Apollo Neuro is the first and only wearable that improves your HRV. Apollo is effortless. Simply wear it throughout the day and night and let it do the work

for you. It's safe for anyone and everyone with no side effects and is the only wearable that can be worn anywhere on your body. Optimal health requires both the mind and body to be in line and Apollo is the key to establishing that connection. Check the description below to save $90 with my special discount. Take control over your health today with Apollo Neuro. to discuss ipomerellin. So I want to give you a quick breakdown and understanding of what it is, what it does, and how it works

all through research that's been conducted. So in short, ipamorellin is a selective growth hormone secretagog. You'll see it marked at GHS. That is a Grellin memetic. And it is known for its specificity in stimulating growth hormone release without significantly affecting other hormones.

I have studies that date back to 1998, titling it B-3. first growth hormone secretagog. So if you want to look that up, just type in first growth growth hormone secretagogue and you will find this study. Now, Ipamorellin is a pentapetide. So that means it consists of five amino acids and it is very, very popular for its efficacy as well as its safety profile. Now I want to quickly look and discuss at the mechanisms of action. So ipomorellin works by mimicking the action of ghrelin. Grelin is our hunger hormone. So how does that work? It binds to the grelin receptor in the pituitary gland. Now this interaction is going to specifically stimulate the

release of growth hormone from the somatrophes in the pituitary gland in a pulsatile manner, and that's going to be very similar to our body's natural growth hormone secretion rhythm. Now, unlike other growth hormone secretagogues, Ipermorella's action is a lot more targeted. So what does that mean? That means you're going to have fewer and see and observe through research, fewer side effects. It does not significantly increase cortisol, nor prolactin, nor acetycholine, nor aldosterone level. So it makes it generally speaking and regarded as one of the safer peptides for promoting growth hormone release. Now, I quickly want to go over some of the benefits that have been seen on research that's been conducted. Just a few.

One, enhanced growth hormone levels. There's been a show of increased lean muscle mass, improved recovery and repair, body fat reduction, as well as anti-aging benefits. Now, dosing-wise, and these are typical studies that have been conducted, a typical dose is going to range from 200 to 300 micrograms per injection. These are subcutaneous injections, and generally it's two to three times a day. I'm more on the side of two times a day, but some research has shown that three times a day can be optimal. 30 minutes to an hour fasted before meals is the best to optimize your growth hormone release. And the time and duration of use is generally shown to be quite efficient and safe at the 8 to 12 week mark. And you're going to then kind of take a break or go away from it for a while.

Synergistic-wise, Ipermorelion is combined with growth hormone releasing hormones like CJC-25. You'll often see them group and paired together. This is very common. The reason for this is that it's going to enhance your pulsatile growth hormone release. Now, in terms of side effects, it's ipomerellin is well known and regarded for its very, very, very favorable safety profile with low side effects. There are some potential side effects that have occurred through research. Injection site reactions, rare redness or discomfort around your injection site, possible headaches and nausea. These are all very, very rare.

And this normally, when it has been seen, it's been right on the onset of use. It's nothing prolonged or long term. So that is Ipa Morelian in a nutshell. It's very highly regarded. It's one of the most studied peptides, most known, and most researched out there. So Ipa Morelian, in short, enjoy.