THE ED MYLETT SHOW - Start Aging In Reverse w/ Sergey Young

Episode Date: October 5, 2021

Is it possible to live for 150 HEALTHY years? How about 200 years? My guest on the show this week, SERGEY YOUNG believes you can! He backs it up with the keys and strategies to doing so. He gives a detailed look into brand new breakthroughs in science and technology that can help you do it now and gives you a vision of the emerging strategies coming the next 10 to 20 years! Sergey is easily one of the most UNIQUE guests I’ve ever had on my show. It’s impossible to not be CURIOUS about what he thinks and how he plans to reach those goals. Sergey is a longevity investor and visionary who founded the $100 MILLION LONGEVITY VISION FUND to accelerate life extension technological breakthroughs and to make longevity affordable and accessible to all. He looks for cutting edge investments that are exploring ways to make it possible to reverse aging and treat previously incurable diseases. He also recently published “THE SCIENCE AND TECHNOLOGY OF GROWING YOUNG” that explores a lot of the exciting breakthroughs taking place and how these may impact you sooner rather than later. Although we touch on the science of aging, Sergey and I spend a lot of time on PRACTICAL steps you can take NOW to LIVE LONGER. Do you want to know what MEDICAL SCREENINGS you should do to let you live longer? Do you want to know the right way to EAT to live longer? How about gaining a better understanding of the importance of SLEEP and why it should become your SUPERPOWER? I know a lot of you enjoy WINE and COFFEE. Would you like to know about how those two beverages affect your health? You don’t have to give them up, but there is an optimal amount for good health. Sergey also gets into an explanation of the science behind the aging process and how it’s possible to more effectively treat diseases than ever before. You need to hear what he has to say about GENETIC EDITING, CRISPR, HORMONE, and OXYGEN therapy. This is not a just discussion about living longer. It’s a discussion about IMPROVING THE QUALITY OF YOUR LIFE so you can live longer… A LOT LONGER!   👉 SUBSCRIBE TO ED'S YOUTUBE CHANNEL NOW 👈  → → → CONNECT WITH ED MYLETT ON SOCIAL MEDIA: ← ← ← ▶︎ INSTAGRAM ▶︎ FACEBOOK  ▶︎ LINKEDIN ▶︎ TWITTER ▶︎ WEBSITE  

This is the Ed Milage Show. Welcome back to the program, everybody. Okay, you ready? You want to live the 200 years old? Did you hear what I just said? Would you like to live the 200 years old? Would you settle for 150? Right?

Well, this man doesn't want to settle for 150. He doesn't settle for 120. And I'm fascinated with him because there's so many mutual friends. He's an author. He's got a book out called The Science and Technology of Growing Young by Sergei Young. It gives you an idea of what his name is because I just finished this book in two days. He's a longevity expert. He's the Benjamin button of Planet Earth right now. He's also founded the Long Jeopardy Vision Fund, which is a fun dedicated to technologies that can extend lives and the quality of lives.

So I'm so excited to have this man here today. There's gonna be a compelling note taking awesome vision stretching conversation. Sergei Young, welcome to the program. Hi everyone, I'm so excited to be here with you today. So my brother. All right, so let's, we're going to talk about things that exist now that can help people live longer. We'll talk about some things that are on that 10 year horizon like you like to do.

And then some stuff that maybe 20, 30 years out. But first off, why do you have this belief? Because average life expectancy now is around 78 years old, somewhere around there. What makes you believe that over the next couple of decades, people may live to 150 years old, maybe even 200 years old. What gives you hope and belief that that's possible? Yeah, so basically this exponential power of technologists,

which finally arrived to this world. Like the science, I mean, could have been exist 30, 50 years ago, but like, it's just a combination of technology and science, which brings us this hope and this desire and finally ability to live longer. Like, 30 years ago, like, US spent $3 billion of government money to sequence one human genome. Right. And 13 years. Right now, just a few hours, right, and a couple of hundred dollars. Again, 20 years ago, this CRISPR thing was available to literally,

handful of people who have really serious genetic disease. They were like really unlucky and genetic lottery. And today we all, you know, part of global experiment of gene therapy. You know, if you look at mRNA vaccines, which is the like Moderna, it's an outcome of gene therapy. So that's amazing. And full disclosure, like the first time that we will be able to check, like what's the maximum lifespan extension that we'll do. It's going to be really far away from here. So I'm 49.

So to check, if I can break the sound barrier of the maximum lifespan of 122 years that we have today and in the world, guys, we will need to stick together for another 73 years. It's going to be amazing 73 years. We don't know how the world will look like in 73 years. It's all about aspiration. It's all about getting the message across. And the message is, we're all going to be living longer or radically longer in this world.

So let's just be prepared for that. Longer and radically longer. And by the way, the book is so awesome because in the book, he kind of takes you through Imagine your life and it's sort of this scenario. And then when you're done, you go, oh, that's just, yeah, that's Star Wars stuff. That's outer space.

He goes, actually, a lot of this is going to be here over the next 10 to 20 years. And it's just, it's fascinating. And by the way, even if you read the book, you'll find that, you know, there may be a belief that it could live even longer than that when some of these, you know, I'm fascinated by epigenetics,

the genetic editing stuff that's taking place now, tissue and organ regeneration guys. I mean, you got your organs functioning, they can regenerate, you know, you have cellular health. This is not pie in the sky stuff. So what we're gonna do today is we're gonna go through the different, you know, parts of doing it now as well. So I want to talk about things that are, they may seem basic. I want to say one thing for me if you agree with this, Sergey, just the intention,

just having the intention of living longer, just making that an outcome of yours as a human being. I believe opens up a space that didn't exist in your life and in your world prior to thinking that thought, just the thought alone that I'm going to live a long time and picking a number, I think too, having a number. Do you agree with that or is that crazy? Yeah, look, I'm big fan of it. So I'm typical placebo man, actually. That's why I like supplements, right? I have plenty of supplements because, you know, the, like 30 or 40% of the outcome of the positive result you know from the supplements comes from placebo effect and I'm so I'm typical placebo man. So my motor every morning I wake up and my mantra is I'm going to be living to 200 healthy and happy years in the body of 25 years old man. So imagine, I started to do it a couple of years ago.

My life has changed. Because imagine every morning I wake up and three fourth of my life is the head of me. I have plenty of plans. I can even excuse myself for three years from this planet to go back and forth to Mars. And my family is not gonna be pissed off. I have four kids.

I'm an investor, so I call it. I'm the founder of diversified portfolio of four kids. Okay. The psychological aspect of aging is really important. I agree with you. So your target age, if you put it like 10, even 20 years below that you've calmed your age, will do amazing things with your body and your mind.

You're so right. Just experiencing you and your energy. I got to tell you, my audience is diverse. There's people 14 years old listening to this. There's people in their 70s. But one of the things when I hit my 40s and 50s, I started to say things that were insanely stupid. Like, I'm old. I'm old now. I'm old now. Just those statements. If people say you're not old and you don't look old either. By the way, physically you look 25 years old. I said, I'm old now, I'm old now, just those statements. If people say you're not old and you don't look old either, by the way, physically you look 25 years old. And I said, I feel it, but just the verbal part of it, and it's not part of the book,

we're gonna get into the details now. I just want everyone to have that intention of living that long in the body of a 25 year old. I love the way you describe that. Now, let's talk about stuff right now. There's six things that Sergey typically talks about that you can be doing right now. And we can go through most of them if you want. But one thing that I do is I, because I've had some heart issues, I do regular lab work,

regular checkups with my doctor. I'm talking quarterly for me. And for a while I was doing it every other month, most people will go years without seeing a doctor unless they get sick. So talk about some of your six things people could do right now to right now engage living longer and more healthy. Yes, beautiful. So for me, it's the most important part of the book. This is why I am in longevity. I mean, you know, all these exciting technologies,

which will be available to us in the next 10, 20 years. This is all great. But for me, change starts today or tomorrow morning, but that's like the only optionality that you have. So some people find it boring. That's why I created this Sergey Young guy. That's why I've developed this horizon to live 250 years.

And then the far-far horizon of longevity to live to 200 years in the form of internet of bodies, human brain, AI, integration, human avatars. But we don't need to wait for another 10 to 20 years. There's so many things that you can do today. Again, it's called boring stuff and to live to at least 100 healthy and happier. Unless you are really unlucky in genetic lottery. And this is like really rare. You need to have

like really rare genetic disease and this is a separate discussion. We work on that as well. There's so many things that we shoot and we can do today. So then one caveat before that, we humans, we like one silver bullet and people always ask me like, seriously, like what are like just one thing that I need to do to score out this kind of health stuff and I'm always saying if one answer to aging and a related disease would exist in this world then it's either mother nature in a process of evolution or scientists in a in a process of scientific research will find this answer. So human biology is the most complex and fascinating field I've ever discovered for myself.

So be prepared, it's always combination of things. And you need to follow through on many dimensions. Number one, and this is one I have 30 seconds on longevity. I talk about this is exactly the thing that you just mentioned, doing your medical screening. We just need to understand what living in a completely different world today. Like 20, 40 years ago, there was zero value of you knowing if you have cancer or not.

It was actually negative value because cancer was a kiss of death and you just kind of got the information that you're going to survive for another six or nine months on this planet and it's it. You've done. People would defer in the cancer screening days, because I mean, there was like zero useful information and an outcome from that. Right now, making sure you do early diagnosis of cancer

increase your recovery rates from 20%,30% to 90-100%. So your opportunity and ability to survive and actually to sustain the quality of your lifestyle and the quality of your health is enormous. And for majority of cancer types, early diagnostic of cancer, stage one, early stage cancer is 93 to 100% for major cancer types. This is amazing. Like some of the machines that we see in the hospital today, it's really space machines, like MRI machines, 3-TESL MRI, they have the artificial intelligence driven brain, right, network, algorithm updated every month. And last two years, so I'm doing my annual screening

every year in San Diego, California, in in human longevity centers that are by our very good friends. So the same place., so two, in the last two years, it was actually, after I've done full body MRI, it was artificial intelligence scanning and looking through my scans. And then it was discussion with doctors. So it's radiologists empowered with artificial intelligence, increase exponentially your chances to get

the analytics right, the diagnostic right, and survive. Just one figure and it's fascinating. So, you every trade theologist working under the time pressure, which is probably 100%, 150% of time, of they're working more. It's successful in diagnostic early stage breast cancer in 38% of cases. Crazy, that's awesome. If you empower the same men and women with a beautiful profession, empower him or her with artificial intelligence algorithm, the ability to detect growth to 98 to 99%. That's amazing. And we've been investing in so many companies diagnostic

comes to our home like you know, all this call of art or using our blood test to detect like the risk of colon cancer. Yes. It's just amazing. So, well, just make sure the most important day of your life every year is a day of your annual screening. If you want to do it quarterly, this is great. Every night is... Just to jump in, I just want to stay on this. First off, I want you to hear what he said there, because I didn't look at it that way. Early stage detection of disease, cure rates and survival rates on most diseases are incredibly

high, detected early. We die from these diseases because it's stage three when we find it. It's stage four when we find it. It's stage four when we find it. In my case, I don't have perfect genetics when it comes to plaque accumulation of my arteries. I detected it in my thirties. I'm still with you here because I was doing regular lab screenings. So, you don't go to the longevity center in San Diego. Get an executive physical once a year. Get your blood looked at. The way that they look at blood now, everybody, it's not HDL LDL. There's little particle, big particle.

There's your liver enzyme levels. There's all these things. There's your lipoprotein little A. There's these things. You don't even need to know what they are. Just know that they're tested for now. And if you haven't been there in a while, do it at least once a year. And I think this starts in our 20s. I really believe that. So I just want to second what he has said there

as if I'm anywhere near the expert he is. But we do have similar friends and we've been on a similar journey. So I just want to really stamp that one is so important. Yeah, this is, and this is much cheaper. Like prevention is 10 to 20 times cheaper than treating something when it when disease manifests itself because this is very old school like 30 50 years ago you need to wait until disease will manifest itself and this is why when

you see a dog right now you define when you need to see a dog and it should be like super regular. So that's one. One. I want one. I want to focus on a couple of them, sir. Just because we have so many of the future things I want to talk about you. Two is let the food be the medicine. I want you to read the book to get that one, guys. That's why you go get a book, right? What's the food? What's the medicine?

Third is get moving. My audience is pretty good at that. Exercise, moving, those kind of things. Here's a biggie. Eat early and less often. What do you mean by that? Can you define that for us? So basically, well, there's a lot of disagreement what actually extends our life in academic circle, but it's one agreement. If you decrease the calorie can take, if you literally decrease the number of calories that you take every day by 15 to 25 percent,

of course you need to look at the balance between physical activity and the calorie intensity. But so it actually extends your life by two, three, five healthy and happy years. That's a big thing. Well it's easier to say, well Sergey you need to less 15 to 25% less in calories, but it's very difficult to do. So what are my life hacks on that? One, I do fasting So, you know, I fast 36 hours every week Wow, okay tonight and one day. It's actually Sunday. Yeah, I started on Sunday evening or on Monday evening And then I you know, it's just two nights and just one day during Monday I just drink you know some water curbolti and it's it so I and just one day during Monday. I just drink, you know,

some water, curbal tea and it's it. So I asked about that. Sergey, can I inquire about that? So, um, because the fasting, I've had intermittent fasting. We've talked about this but 36 hours, Phil Mikkelson, the professional golfer, started doing that about two years ago. He's been a guest on my show. He says he feels literally 20 years younger doing it. When you began doing that, because I've not done it, I've done some intermittent fasting, like 36 hour thing, okay, I wanna ask you about this. Did you just write off the bat, goes 36 hours, or did you build up, did you do 24 for a while,

or did you just go 36, and you're fasting for the 36 hours? Yes, so I started to do 24 hours fasting, but then it's, well, what is happening? Like, in the first 17, 18 hours so fast, and I'm speaking about the average man or woman, right? We are not average like this. Let's say it's actually a beauty of technology. It's gonna be much more personalized but like within the first you know 16 18 hours of fasting, but it just cleans itself, right? Your topology actually start after right? Your topology actually start after the spirit. Well, that's that's the beauty of that. When you're old cells, which your body doesn't need them. Yeah, you can actually clean it in the process of fasting. But as this whole thing starts after, you know, 17 of 18 hours of fasting,

that's why I didn't feel really, I haven't thought that it's logical just to do like 18 hours of fasting and then like the sweetest period, like the best period of fasting, I start to eat again. Well, so I've done 24 hours and then I thought, okay, well Sergei, I mean, you sleep in during the night anyway, don't you? And I'm like, okay, well, that's a treat, but what I can do. So, and I thought rather than starting to eat, so imagine I start Monday evening, run and starting to eat on Tuesday evening, I was like, can I just extend it to like Wednesday morning?

And obviously, it's difficult sometimes to go to bed if you're hungry. And do you get hungry anymore? Do you still get hungry? No, I'm not eating., what I do in the evening. I just like I take fiber Yeah, yeah, and it's yeah zero calories with the water with herbal tea It feels my stomach a little bit and then I go to bed. Oh, but like Literally, you just need to see me like on Monday evening at 9 p.m. what I'm going to bet after first 24 hours self-lipped. This is the best sleep I have during my week.

You feel so light, you feel so energetic. I mean, you literally feeling young and that was the beauty of that. Yeah. I'm going to start Sunday night. I'm going to start. Yeah, just give it a start. But make sure,, like, you know, pre-fasting day, post-fasting day, it can't really do it on vegetables. Don't do a lot of like heavy stuff like meat protein or fish protein, etc. But

otherwise, like the best diet is a balanced diet. Everybody that's listening to this, that's a bodybuilder, except out of the point, then if you're a body builder and you're training for huge muscles and you're not going to fast for 36 hours because you're taxing yourself and you may need some of those proteins, I think listening to what Sergei has said about 15 to 20% less caloric intake, you could still get away with doing that by just because of these body builders, these fitness people that listen to my show, that segment of the audience're incredibly food disciplined already right yeah just focusing on that because that is the consensus in aging less food processed through your body longer life by two to five years so that's this is why I had Sergei on you guys I do think it's important to put it in the context of

your physical routine as well so I mean you don't need to be binary about this whole thing. But like, if you take out this kind of fasting pressure from your everyday, you're following like 18 hours of fasting and like six hours of food intake, if you just put it in the context of the week, it might be actually much more useful and easier to implement. Okay, so guys, I wanna to go through his list with you. One, get regular checkups.

Two, let the food be the medicine. Three, get moving. Four, eat early and less often. And then the last two, I'll have you talk about these. Five, is constantly work on quitting bad habits. And six, is make sleep your superpower. What are those bad habits and what about sleep? Because that's changed my life, my

sleep situation. I'll let you go there. Yeah, so bad habits. Basically, like sometimes we do really stupid or risky choices in our life. And that's the problem. And people think it's something superficial. So tobacco smoking, it's minus 10 years from your lifespan. And this is so full. And I thought it's pretty rare because we don't see this people on this street because right now, from regulatory perspective, it's prohibited. But like, if you look at statistics, 25 to 30% of adults is still doing tobacco smoking, minus 10 years. Not always using your seed bales is minus two years from your life. Just riding motorcycle is 17 times more dangerous

than driving the car. 17 mortality rates from motorcycle accidents is like 17 times car and then alcohol. Yeah, alcohol and coffee like to my favorite questions. So I'll come back to that. Just one final example, which I wanted to mention. So I've been blessed with a lot of travel experience. A few years ago, I just went through the book of Team Ferris for four hours to work

with and I had my wish list. So I went to North Pole and South Pole. And actually, I mean, it sounds really risky. It's just beautiful places on earth, but it's not that risky. So then I've got an opportunity to join the group of guys who are climbing Mount Everest, the highest mountain on earth. And I look at statistics there,

and it was like six percent mortality rate. And I said, oh, look, I'm not sure I can afford that. And about here's the story. Two months ago, I see the email from my very good friend from California. She's an amazing woman in Turpaniore. And she's like, well, Sergei, I'm about to climb the most dangerous mountain on Earth.

And so the name of this mountain is K2. And you know what mortality rate for this is 25% So Russian rule there, right? It's just it's 17% yeah, it's a dangerous game. It's like 17% of dying. It's like really Yeah, putting your stories but like one out of four is not gonna come back. I'm like, oh no, I'm not in this business. So that's very important. And we think it's not with us, okay? It's about some other people. We never do this kind of stupid choices.

So the polite version of this called passive longevity. I do think it's extremely important. Okay. So that's one. And sleep, you know, I always, and probably I don't know if you have met you Walker on on your show. Amazing guy. It's a new book called I think it's called Why We Sleep. This is my book of year 2019. I changed completely my sleep routine because before that we all very active people, we want to do this, this and that,

and there's so many exciting things in the world. So I was just boring my hours from my sleep credit. I literally, my every sleeping time was somewhere on five hours. And I'm like, but after this book, like my rule is eight hours in the bed, seven hours of sleep. And I measure, I actually, I just started to test whoop.

I like whoop, sleep algorithm. I actually have 97% sleep efficiency this night. Where's my sleep? I use aura. Do you like aura? Yes, I'm actually, it's in my home. So I'm using aura as well. I actually find aura algorithm a little bit more forgiving.

So sometimes you have not a great kind of night and OR is stuck. It's good. It's good because I'm a positive person. Even if something is bad, if I name it positive, it's actually positive for me. But nevertheless, I don't think, I don't think it does matter like what particular wearable you use.

All of the algorithms that you can use, it's great for that. But I just wanna quote a very good friend of mine. His founder of longevity clinic in London. And so first I met him, same question. What is the one thing that you would suggest me to do? And he's like, Sergey, every evening, we can visit the most powerful clinic in the world. We go to that. I'm like, oh my goodness, what a beautiful way to put, yeah,

this whole thing and describing importance of sleep. It's like, we can't really underestimate there's no alternative activity to sleep in terms of sustaining your hormonal balance. This is extremely important. And like, and hormones, the things like, and I do think you discussed it with David Simpler, right? Like any extreme is bad. Like lack of hormones is not like excess of hormones

your aging is accelerating. But like, so your body has this beautiful mechanism that you can't really figure out for this, you know, medical signs or artificial intelligence, how to balance your hormones. It just works this way. So use that. You, you blow my mind because, um, and we're going to get to wine and coffee back in a second. And then by is we're going to go to future things, like some of them are the future. But I, uh, I wanted to ask you about hormones in a minute too. But I wanna say this one thing about the sleep

that he just referenced. In my first book, I kind of almost bragged about the fact that I went on less sleep than most people. And as I've done my show for a long time, done more reading, more research, it's one of the things that I am most focused on in my life is my sleep. And I just want everyone in the audience to know that. Research it, you know, the rep, I've had Sean Stevenson on

my show. I've had lots of people about sleep. I've got apps I used to help me sleep deeper. I've got Orr, the tracks that I've got the cool room. I've got a chili pad that David or that Tim Ferris talks about. I do anything I can. The room is dark. All these things they teach you to get into the best sleep state because people like Sergei have encouraged me through their writings and teachings to do it and it's made a huge, huge difference for me. Okay, we don't want to skip over wine and coffee. Does it hurt us and how much? That's just that. Okay, so this is a funny, this is a lifestyle perspective on that. Well, I'm a big fan of red wine, specifically American wines.

After I started to do a lot of business in the US, I'm in love with what you guys have there. So, and I started to dig into this station, and I'm also a big fan of coffee. Okay. So, I do believe you need to have your kind of cheat things, but it's a burger on Saturday or for me, it's one to express so they so my answer is like, if you look at the research on

bofian wine, it's the graph always looks like that. Okay. Tell everybody what you're describing for the audio people. What are you showing? So you can see that there's like, the graph is pretty flat, but there's like optimal point, which is one or two glasses of wine

for occasion or one or two espresso a day. Got it. So you have this in statistical terms. You have like relatively, so you can always say like, you know, one or two espresso days good for longevity. But the shape of this curve is in statistical terms, it's really insignificant.

So there's like, unless you really overdoin this with coffee, or you really overdoin this with alcohol, with coffee, or you really over doing this with alcohol with wine. It's just, I don't think it's influenced a lot your longevity, but Kevin said that alcohol and specifically says excessive consumption of alcohol is a really bad thing for your body, because from certain point of view, after one or probably two glasses, your liver changed the way it's processed the alcohol. Because before like, you know, one glass of and during the evening, it can absorb, you know, everything, it's going to be, you know, super friendly for your body.

After that, well, it's completely different mechanism. Okay, it's actually converted the whole axis of energy and alcohol into fat. So that's, that's a problem. So my rule is, I wanted to glass this per occasion, which is basically my definition of occasion, and it's either Friday or Saturday. Okay. Once a week, and this is fine, you can do it. But not more than two glasses of red wine, particularly red, I think white is particularly beautiful as well, but not every day, because after age of 40 or 45, you'll find yourself in a trouble with everyday conception. Even it's just one glass, it just changed your, you know, it's like, look at it, if you use

or ring or you use, like whatever, algorithm to trek and sleep you currently looking at. You can see that after couple of glasses of wine, your deep sleep period starts not around midnight, but somewhere around 4 or 5 am. Yes, that's right. This is bad. And the same thing with coffee. And there's two group of people, one is they're really receptive to coffee and coffee and like, so if I will drink a couple of espresso after 2 p.m., I will not be able to sleep well, okay? And for me, again, deep sleep actually, a period starts somewhere around 4 or 5 a.m. during the night, not around the midnight. This is bad.

I know a couple of friends, they can have like two espresso in the end of the dinner, and they were just like almost that in a bath in the next 30 minutes. So I think there is a power of the example that we just used. And the power is like 30, 40 years ago for you to do experiment and longevity,

is 15 years exercise. You take a group of old people and you wait until all of them die. This is your feedback cycle, 30 years ago, okay? And what you can do in this world with 15 years feedback cycle, right now, it's like that. It's every minute, right? With every variable you have.

Like every morning, you can look at the quality of your sleep and have very important takeaways for your lifestyle changes. So that's how we, both you and I discovered that, both caffeine or alcohol in the form of wine or any other bad habits, actually, in negative way, influence our sleep. So that's the beauty off the feedback. Got it.

I like that we're allowed to drink wine a few days a week and have coffee because I want to be alive 150 years or 200 years, but I also want to live. You know, it's not just being alive, I want to live. And I, I, wine is part of how I feel. I'm living sometimes. So I feel good about that.

All right, let's talk about some future things and some just kind of stuff that I always wanted to ask you that how you good about that. All right, let's talk about some future things and some just kind of stuff that I've always wanted to ask you how you feel about it. Cellular health often is discussed, you know, is the key to having longevity. For many, many years, and we won't get real detail here, but for many, many years, people meant thought telomere length was lifelength.

The other thing that people thought was free radical damage was that's aging. In fact, I've had guests on recently that still are talking about free radicals in the body and needing to rid us of them and Now I want to know what you believe like as David St. Clair said look more and more research says maybe free radicals Don't contribute to the aging process. You say the similar thing in your book, you quote that in the book. So free radicals in general are detrimental to our health. I assume you believe that, but not necessarily detrimental to aging. Or do you think they're a non factor either way?

That's a $1 trillion question. So in a few words, number one, we don't have a unified theory of aging in the world, right? There's a lot of disagreement with actually cross aging. And like, and you know what, what I like in this case is, I'm always wondering, like, okay, this is all great, all this scientific disagreement, like, what are these stuff that you guys using? And this is the question I'm always asking to, like, the biggest professors in the field. And they all use in this nine or like, what are these stuff that you guys using? And this is the question I'm always asking to like the biggest professors in the field. And they all use in this nine or like, is it explaining the book ten full marks of aging? So that's basically explains all the roots, all the sources of aging in our body and in our mind and and give us a lot of powerful takeaways.

So one, there's no one thing, there's no silver bullet, right? What is free radicals? I have a lot of doubts around free radicals and or telomeres or your genetics to top. Well, actually, your genetic is responsible for 30 or 40% of your longevity. And you can take a different view on that. You can say, well, it's all genetically pretty fine.

Or you can say, this is great. 60 to 70% is under my control. So I'm going to change my life. And this is where we can talk about epigenetic, right? The way how our genes express themselves inside our body. It's still a meers. So I do believe, you know, all these different hypotheses, they're

not necessarily right or wrong. They work in combination. And we already know like all 3,000 genes in our DNA which are responsible for aging processes, fall on javelty. And they actually work pretty well in, if you do genetic analysis of DNA of people who live 100 years and above on this earlier, they call it since an errands. Like,

all these 3000 longevity genes are particularly working well on their DNA. So what I think we wrote 50 pages to chapters on different years of aging for the book. And in the end, you know what we did, we put it on a show, okay? And it's very, very, very, yeah. And it's a very short chapter. I think it's both chapter number three, different theories of aging and why they not necessarily matter in this world. So that's the whole thing. And but just understanding complexity of this and understanding some of this is genetic right you can and today it's beautiful we we can know where we are weak or we are strong in genetic terms and you can do a lot around this and some of the things in just in our lifestyle and and and using the food as medicine or

physical exercises or detecting the earliest signs of the very dangerous diseases. So I do think there's no right or wrong answer. We have only one framework, which is nine hallmarks of aging, which confirm it shows the complexity of the human biology. Do you think that let's sell the dream a little bit? By the way, I'm really grateful you answered that way because David answered it very similarly. Although I do feel like you guys lean in a direction, and I'm not speaking for you, that maybe some of this telemetry length and some of this free radical stuff is overcooked

to some extent, and there may be better markers to track going forward. But let's sell the dream a little bit. What does, so I think most of my honest does not know what genetic editing looks like, or they think it's some futuristic thing that's, you know, 40 years into the future. Can you talk a little bit about genetic editing, CRISPR, any of these technologies in general that are literally altering life spans now and altering potentially the DNA of a human being. And I think people need to know this is right, some of this is right here, correct me if I'm wrong soon or even currently.

And then some of this stuff is 30 years from now where we're going to be, you know, putting a chip in our body that measures all of our levels all day long and recalibrates all of it. But tell us a little bit about genetic editing in CRISPR in general. So as we discussed, depending on the sources, 30% of our health is defined by our genetics. So it's extremely important. And in some of the cases, if you have red genetic disease,

it's much more damaging. So your genes are working against you. So a few decades ago, there's nothing you can do about it. The whole thing started with our ability to sequence human genome, just to see the composition of our DNA and look at the different genes, how they express themselves, and basically do the mapping, like which particular gene responsible for this condition? Either better or good in your body, like the good genes, like longevity genes,

some of the bad genes, et cetera. And while it's called reagent diseases, they know that rare. There are 400 million people on earth suffering from that. So, let's look at evolution. What we have done in the last 30 years in this field. So again, 30 years ago, first human genome has been sequenced, $13 years, $3 billion.

Today, when COVID, when we discovered that this thing called COVID in this space, and obviously, virus genome is different from human, it was in a couple of days where genome of the virus of COVID has been sequenced in so many countries on earth, which gave us enormous power to develop vaccine. I was just reading in use, I think it was in your times like a month ago. And in the name of the title or article, Moderna vaccine has been developed in a course of two days.

Two days, this is amazing. Obviously they did a lot of work like decade, or even decades before that, like Bob Langer and a lot of these great people who created this. But in the end of the day, this is the speed of invention these days. So 30 years ago, CRISPR, which is basically genetic scissors, like what it does is the certain protein

charged in a way that it's fine, this similar sequence in your own DNA and cut it out. Or this version of this can replace the gene. So it's cut out certain genes and bring the other genes in your DNA. So that's how CRISPR work. And in the end of the day, one end of the question is, well, that's a pretty dangerous.

And it's extremely important surgery, okay? Because if you didn't manage this well, the person can die. And they say, this is the story from the book. This is what happened 20 years ago with one person. And then the whole, you know, field of genetic has been silent for like 10, 15 years. Again, so then, then, then is the genetic level. And it's the other level called epigenetic, right?

This is what you discuss with David Stimper. And this is how, you know, different proteins, which, you know, help our genes to express themselves in our body. Well, this is really easy to manage. You can do a lot of different things with that. So, but just looking at evolution of our ability to influence our genes, Again, 400 million people. So, 30 years ago, handful of people, they had nothing to lose in this world. They were about to die. That's why they were really happy to go in a trial and be a part of this CRISPR technology, this genetic sister experiment.

In the last 10 years, people were working on different, like, orphan disease, right? Rare diseases, like 400 million people on earth, very expensive procedures as well. These days, we all participate in a global experiment in gene therapy because Moderna and some other vaccines, mRNA vaccines, as the outcome of gene therapy. And look at the afford, the ability aspect of that. Look at the how quick we've been able to develop our response to COVID.

If COVID, time would happen, we have been happened 50 years ago, the death toll would be completely different. Yes, especially in people. I was just reading something that said that if that were that long ago, that the population in the world, 55 and older may have been 70 to 80 percent extinct based on different

mutations that may come. Had we not put it off at the past, at some extent, that's an unbelievable statistic. Yeah. So that's why I'm very excited. We're living in a unique moment of time where you know intersection of scientific discoveries and empowered by technological breakthroughs. Finally, give us an opportunity to create a completely different version of healthcare and the version of health, which is much more affordable, accessible, personalized, data-driven and technology-based. My dream

is for the healthcare and hopefully my mission, healthcare to become like a basic service that you receive from the government for free. And look at the technologies that we investing in through longevity vision fund, like cost of a con cancer diagnostic 10 times less. And this is the real numbers of the companies and products they bring into the market in a few years from now.

Cost of ultrasound device. 50 times less. 5.0. Crazy. This is amazing. Or this organ regeneration technologies that we invested in. It's a company called Genesis. They're based in Pittsburgh.

They just take human liver, donor liver, split it in 50 to 75 pieces. Use very simple operation to put it inside your lymph node. And then like a new liver grows inside your body and supports the function of your sick liver. This is just amazing. I want to just say this, I got to go back so people to catch everything. I've been reading about the Genesis because of you. And guys, I want you to understand what he just said to you. They can actually functionally regrow organ tissue, right? You understand this is now, this is happening now, and his fund invests in this. And they do it somehow. Don't they, you started to say it and I interrupt that you

start to apologize, but it's somehow through the lymph node somehow, right? Yeah. It's cellular therapy through the limpoids. It's actually here. This is like the best lymph node for you to regrow. But it just pointed to a lower abdomen area, you guys. Yeah. Yes. And again, like in this world, we have one-to-one donor to receive in relationship. There are 117,000 people on the waiting list for donors, organs in the US only. 17 people die every day because they couldn't survive for that long. Well, this is the opportunity for us to solve this problem. It's going to be just one donor helping 50 to 75 pieces.

And this is not the science fiction. So they've done testing on mice, dogs, primates, peaks. And this November, they start human trials. They just got FDA approval earlier. It's incredible. It is. And then forget about liver. And then they start to work with kidneys and they actually start to

work with thymus. I don't know if you know the story of thymus. It's like a special organ, which is responsible for our immune system inside our young body. It's actually, it's got maximum performance until the age of 18 to 20, until you just, in evolutionary term, you just come into your reproductive period, when you need to reproduce. And then after age of 20, it's gradually start to shrink.

That's why our immune system, wow, it's not disappearing, but like it's shrinks in size like really significantly. Our immune system is always going level down, It's not disappearing, but like it's it shrinks in size like really significantly our immune system is always going level down level down and every year after this age. And well one of the program number three in like Genesis of the kidneys is actually regeneration of thymus. Wow, wow, wow, wow. And if we will be able to support our immune system, like you know, forget about COVID, forget about cancer, forget about, you know,

a lot of other things. And if you think it's scary, think about people who are actually really needed in this world. So like, when I talk about human brain AI integration, like brain computer interface, which is, you know, people know Newerling from Elon Musk, people need to say it's scary. Well, I'm like, guys, what about people

who suffer from dementia? What if we can use human brain computer interface to help them to leave the last five years of their life? Fully integrated into society, this feeling. I hope people will do a little research on Neuralink Elon Musk company, because I don't think it's scary at all. I actually think it's absolutely fascinating.

And I think that legendist is, it's a world-changing proposition we're talking about here, guys. I just had Rod Caru, who is a very famous major league baseball player on my show, who had a heart transplant. And he was very fortunate that he actually had a relationship with the family. This young boy, he meant toward, ended up dying. And he got the heart of this young boy. And I thought how great flow is because this man was actually a meant toward me. But then I thought for a minute, not that many people are that fortunate, that they've got some relationship that they happen to get an organ donation like that. And just literally millions of lives we've lost that if legendicist's technology continues to evolve, guys, these things can go away at some point. And you start having organ health,

you start having longevity that's off the charts. And so, and lives saved, not just extended, but lives saved. And so, this is the stuff, this is why I wanted Sergei on. I think he's one of the most wonderful, fascinating men. And he's not just thinking these things, his longevity fund is investing in these technologies to make them real.

And it's he's a very valuable human being. He he he someday could go down as someone who's literally rewritten history for millions of lives. And so I don't take lightly that you're here, brother. And I don't know that you always get acknowledged. He's bowing. I don't know that you always get acknowledged for the unbelievable work that you're doing because I there's not that many. always get acknowledged for the unbelievable work that you're doing because I there's not that many. Really the longevity crowd, the longevity field. I know about everybody in it now, right? I mean, it's a very small group of brilliant, kind, generous souls who are just trying to change mankind. That's all they're trying to do, but it's not a very big group of people ironically. And there's all these millions and millions of dollars

that were spent on all this research on these diseases. And now they're coming at it from the other angle. And it's this other viewpoint that to extend life, not just solve a problem, that is actually solving the problems that we were unable to solve the last 30 years. And that's why this approach, this higher level bigger thinking approach

is actually solving these problems that have plagued human beings for so long and taken lives. So, having said that, a couple rapid fire stuff. How do you feel about NAD? You like it? You don't like it, does it extend life? It's right there, he's got a bottle of it right next to him. Yeah, yeah.

So, I look and I do think it's something behind that. And just speaking to like David Sinclair, Eric Verden, the head of Buck Institute of Aging Research in California, Peter Diamantes, like everyone who started to take NMN or you can, you know, the other version of NAD booster, something like Elysium Basis or Trunage and from Chromodax. There's something behind that, the level of energy and specifically a physical performance is increasing. So I'm using NMN and it's,

the call, the one you put on the tongue, sublingual version of it. Yeah, be too. So I'm gonna, but remember I'm placebo man, okay? I know, so am I. What about the 40% yeah? About so we got, get regular checkups, let the food be the mess and get moving, eat early

unless often, constantly work on quitting bad habits, make your sleep your superpower. We know about these other technologies. We've talked about 36 hour fast, potentially, or 24 hour fast. We got an endorsement of NAD We talked a little bit here surge earlier about hormones and I did talk about that was Sinclair Yeah, are you to me visual aging?

So I have friends that I've been candid about this I take testosterone therapy. I had very low testosterone I take it and I get my levels to what would be a normal, what they call a normal measurable level. I don't want to be too high at my case. I also didn't want to be at 150 as a male either. So I'm open with what I do. I take NAD also, but I do take testosterone. To me, visual aging, like when I see somebody that, I'll give an example. I don't think this is a secret, but my dad and, because he's just, well, I shouldn't say it.

There's an actor that's very well known, that's made a lot of movies who's kind of known to have taken testosterone for a long time. Who's a friend of mine? And he's about the same age of my dad who passed away, my dad passed of cancer. And by the way, did smoke and had some of those other events, but also exercise and eight great, but did smoke prior quit.

But I think the damage may have been done when he was younger. Visually, my dad looked considered, very much more handsome guy than this dude, my dad was, but my dad visually looked older. So from a visual standpoint, the person who sustained a normal functioning hormone level in his 50, 60s and 70s, at least aesthetically looked much younger than my father did who did not do any hormone therapy. So I'm just curious, does it have a stamp of approval? I'm not sure. Don't do it. What would you say? I think one is there's an easier way to fix the like a moderate level of problems with hormone disbalanced, which is sleep, and we discussed that today.

So that's important takeaway from our conversation. Second, I do think this, the key word here is a balance. That's why we always talk about hormonal balance. So with human interaction, it's just very difficult to find the balance. OK? So that's why I'm a great believer of unless it's just a matter of your death and life.

Don't touch this. But I don't have a lot of evidence behind it. So I'm pretty sure there's a number of people on the planet, which would really need this. But for the rest of us, there's so many options available to us. And I'm looking at you. You are not on any hormone replacement therapy, correct? And you look younger than me.

I'm really afraid. Yeah, to like, because I've been diagnosed for three times with excess of healthy living, okay? Because like every time I'm really ready to commence, every time I try to do something, I'm like, I'm just go to the extreme. And I'm like, well, Sergei, your body starts to work against you.

Yep. And that's it. I want to be clear too for my eyes. I'm certainly not ever recommending that. I'm not a medical doctor. I don't know what's right for everybody. I know putting any exogenous anything in your body has some deleterious negative effect. I also even know in my own case, I'll just say to everybody that there's some evidence that testosterone can suppress HDL and I already have low HDL. So there's all these

ramifications once you start putting things in your body. And then once you've done it for a long time, you're sort of stuck doing it forever because your body stops producing it So yeah, yeah, certainly not recommending it But I just wanted your take as a longevity expert just visually what I've seen How about oxygen and oxygen therapy for cellular health? How do you feel about that? You're smiling. So I'm doing this every year and it's 10 sessions 45 minutes each When I come to Moscow to visit my mom during the summer, so I just go to like space center

when they, like the whole tool they use for astronauts. So there's clear evidence of oxygen therapy, positive effect on your brain health, okay? Or there's evidence of this supporting your recovery after any kind of shocks related to your brain health system. So that's one thing. Second thing, there was a very interesting study, I think it's in Israel, for 60 days,

they put people who were, they were like 55 plus years old in Oxygen Chamber for one hour, but it was like in the course of 60 days. And obviously they get their age reversed. I do believe there is something behind that. And it's specifically like, if you need to work on recovery of your brain functionality after your health shop is an important opportunity and an important intervention,

I do think there's a natural limitations to like really scale up this technology because like producing the oxygen, oxygen it's like it's very inflammatory so if you're in a chamber you can use anything you know it's it should be like 100% column where so like I just like I know it sounds a little bit idealistic but my mission is to change one billion lives so I'm not really interested in something which would make me younger, but like what about other people? So it's a rare, exotic,

useful intervention. Can we use it to solve and bring affordable, accessible version of healthcare? I'm not sure. Okay, good. I love that. That's why I'm asking, because it's become more and more a protocol

for healing after surgeries. So I've thought, you know, is there some tissue benefits to the oxygen that other people on the show, even recently who are big believers in oxygen therapy? And that you know. But you know, what can I just say something provocative?

Like every moderate shock to your body will produce a result, okay? Well, that's why, you know, always different diets, they produce the outcome. Your body is like, oh my goodness, what is happening? You know, but I'm coming, you know, I need to then, you know, cold shower, like, starvation, fasting, oxygen, hydrogen.

So, it's, this is the way it works. Again, this is, don't take it that face-villain, but it's just a little bit of provocative thoughts for our audience, like just challenge your body to the extent that you can and don't go to extreme, but your body will respond to that. Very good. So reason I'm asking a couple of things that aren't in the book

because I also want people to get the book, which by the way, is a science and technology of growing young, by Sergei Young. I read it in two days. I probably could have read it an entire day but my flight ended. But it's fascinating. It's like you just keep wanting to turn the pages

because like we said, there are applicable things that you can do that are practical right now to extend your life. And then there are things that are here, he does these horizons that are amazing. Like here's 10 year horizon, here's 20, here's, what could be in 30 years. One more question on that's not in the book.

I'm just curious if you've done any research on it, which is red light therapy. I've been hearing more and more about it. I do it now. I actually have a red light bed. I do it more as a recovery mechanism for my working out. When I go, I have to say Sergei, when I go speak to these college teams,

these pro sports teams, see a lot more red light beds there. And that's an athletic performance thing potentially. But I'm just worried, I'm curious if there's been anything you've thought about or read about in terms of life extension as it relates to red light therapy. Yeah, I haven't seen a lot of evidence behind that. So like when I visit my, you know, and I'm pretty sure I would friend Dave Espray haven't seen a lot of evidence behind it. So like when I visit my, you know,

and I'm pretty sure our good friend, Dave Espring, in Upgrade Lab in Santa Monica, I'm kind of trying this, but this is more exotic. Well, like the one thing which can be helpful here is this potential effect of red light therapy on your vitamin D level. Okay. Because if this relationship exists,

that is actually transform this from recovery, from athletic kind of intervention to much more useful. Because we are all deficient of vitamin D. We always sound to the roof, right? In a car, in the office, you know, in a gym or at home, and that's why taking vitamin D is in supplements. This can be a very good substitution or supplementation to that. Okay, but not a major game changer in your mind. Okay, he's nodding no. This is why, guys, everybody, this is why I have someone like him on the show because I want

the most up-to-date research on these things. I also want obviously a cross-section of opinions on this stuff. Okay, so we've covered so much today. Tell us a little bit about what X-Prize is because I think it's something that there are also people listening and watching this today that have great ideas, that have, you know, innovations they thought of or created, and maybe they don't even know where to go or what to do with it. So tell them a little bit about what X-Prize is and how you're involved with that. Yeah, some innovation board member of X-Prize Foundation,

the based in Calvary City in California. And the whole notion of X-Prize, and this is like real example, you go to Elon Musk or someone like him and say, Elon, would you give like $15 million to the team who would solve one of the world biggest problems? Like helping kids in Africa, learning so a helium in English, or people in prison do the

same to become literate. And you pay for results. So you create a competition. You say like the winner we're going to get is $15 million from Elon Musk. And it's actually called Global Learning Express Competition. We finished this back in 2019, I guess. And two, three, four hundred teams all around the world from 50 plus countries. It's starting to develop this solution and it can be to solve this world biggest problem.

Actually, the second express that we've done with Elon, we started earlier this year, it's called Carbon Removal Exprice and it's $100 million to the team or teams who would develop the technology to take out CO2 from the atmosphere and put it in a minimal viable product. So the ex-price competition that I'm working on is H-versal ex-price. So what we're gonna do, and we have amazing advisors

for design of this X Prize, like David Sinclair, George Church, near Barcelona, Steve Ford, the man who invented the first biological clocks. So what we're gonna do is just measure the biological H of the people in question within the 12-month period. And like the winning team should demonstrate the maximum age reversal. Got it.

It's 12-month. It's obviously it should be approved intervention. We expecting at least three, four hundred teams to compete for this X-Price. We currently in discussion with different sponsors for them to donate anywhere between 50 or 100 million dollars, but we're gonna pay, and, or this person gonna pay only to the team or teams who actually develop the technology or intervention,

or will bring scientific discovery breakthrough to do H-versal. And this is for us to wait, way to fight a traversal, sorry, age-related diseases like cancer or heart disease diabetes. And it's just a lot of fun. It's it's amazing the work that you're doing. I feel like we're on the precipice of an acceleration right now, but I don't just say that to be ra ra. I feel like we're at a time in our history, we're on the precipice of very much Accelerating the things that you have in your book really that that 78 number feel like there's a really great chance over the next decade or so

That number significantly higher with with all the things the tissue regeneration the the epigenetic stuff that we're talking about these the research You're fund and just people doing the practical things that we talked talking about, the research, your fund, and just people doing the practical things that we talked about today to just live better and live longer. I'm so optimistic about it. And by the way, I have a million other things that I wanna cover with you. People that know my show know what room is he in right now?

I had a pipe burst in my house. And so there was no way two weeks in a row, I was not gonna have this man on my show because I wanted to share his brilliance with you and I wanted you to have this information. At the same time, there's no plug in here. So we've gone an hour and I've got 4% juice on my laptop. So we're a very sophisticated show around here.

We get millions of audio downloads. I know that it's, and I'm on a laptop in my bedroom, which I think is that should give everybody hope out there with a dream that you can accomplish whatever you want because you're listening to two guys right now. Sergey, 20 years ago, if you look into his background, you would not think he would be one of the cutting-edge people on planet earth, on altering life duration, but he finds himself doing that. And you certainly, if you knew me better, would not think I'd have one of the most far-reaching shows in the world that reaches millions of people because I prove it every week on my

laptop that I still don't know what I'm doing. So I just hope it gives everybody hope with a dream. Sergey, you're awesome. Today was incredible. This will be shared to millions of people. I can feel it just simply because the information is it's not found anywhere else. And it's also more of it, by the way,

is found in his incredible book, guys. And I'm not a big book seller. You guys know that. This is a real book you should read because you all want to live longer. When I asked you in the beginning of the show, do you want to live the 200? We've talked about some very practical things today,

and some things that aren't that far away that could very much make that a reality. So, Sir, gay, any final thoughts you want to share with the audience before we wrap things up? Guys, don't wait for 10 or 20 years for this beautiful technologist to arrive. The time to take back responsibility and control over your health is today. So stay healthy and happy. Stay on longevity breach, please. I love it. You're amazing, brother. We're going to do this again.

I want to do one with me, you and Sinclair in one room. We'll do that in the next 12 months. We're going to do a lot of fun. Let's do that. Because the updates will be even greater by that time. Hey, everybody, God bless you. Let's live longer. Let's live healthier. Let's help more people.

Let's make a difference in the world together. All of us collectively in the max out universe. God bless you. Let's live longer, let's live healthier, let's help more people, let's make a difference in the world together. All of us collectively in the max out universe. God bless you all. Share this with people you love and care about. This is The End My Let's Show. [♪ OUTRO MUSIC PLAYING [♪ you