The Highwire with Del Bigtree - NEW SCIENCE SHOWS MRNA JABS WEAKEN THE IMMUNE SYSTEM

Episode Date: September 27, 2024

Research is piling up to reveal that the mRNA vaccines increasingly weaken the immune system with each booster. Jefferey dives deeper into what “HighWire” guests Bret Weinstein, PhD and William Makis, MD both detail – multiple vaccinations causing a class switch in antibody production to an overproduction of IgG4, the antibody responsible for dampening immune response, and underproduction of IgG1 and IgG3, the antibodies responsible for cancer surveillance.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.

Last week we had a podcaster, Dark Horse, co-host Brett Weinstein, Professor Brett Weinstein on the show. Extremely informative interview with both you and him. And during the interview, he said something that had a lot of our viewers pause right in and say, wait a minute, I can't believe what he just said. And so we want to play this here because that's going to bring us into the next section. Take a listen. All right.

This IGG4, if there's a weakness, as you're saying that an enemy could utilize it, but they all took the vaccine too. Clearly, if that's a vulnerability, any enemy is going to say they can't, like, create a weapon to attack the vulnerability because they're vulnerable too. I don't think so. In fact, I believe it is correct to say the Chinese did not inoculate their population with anything MRI-based or spike-based. So this would be the separation between populations that weapons makers are seen. seeking just in a direction that is extremely unfortunate for the West. So what are we talking about? We're talking about the MRNA vaccine, the COVID vaccine, and we want to go a little

bit deeper into this because we're talking about the after effects of this, something, obviously we're reporting on it for years, but these layers upon layers that keep coming out of the possibility of something, a detriment this vaccine has had on people. And so when Professor Weinstein was in our studio, he walked down the road just a little bit and he sat down with Joe Rogan and spoke about the immune effects of the COVID vaccine, specifically the mRNA vaccine, to an audience of millions of people. And it's interesting now because the idea that the COVID vaccine may actually harm the immune systems of certain people is now becoming mainstreamed. And it sounds like this. Take a look. Why is it we are dealing with a simultaneous

panic over Eastern equine encephalitis and West Nile virus? Well, that is a very odd coincidence. One thing that's true is the last panic was over COVID, and the response to COVID was massive vaccination with the MRI shots, as you know. The MRI shots, for anybody who got two or more, triggered the production of something called IGG4, which I don't know

if we've talked about it before, but IGG4 is the immune system's own message to itself to turn itself down. Okay? Why two or more? That's just empirical. I don't know whether anybody expected this result, but when it was pursued, that was just the number at which we could detect the

presence of ITG4. So not with one? Not with one. I'm not saying there wasn't any with one, but we don't detect it with one shot. And then two produces some effect and the more shots you get, the bigger the effect. Does that explain why disease itself appears to have changed in the last year or two? Now, I want to go deeper into this, something we do on this show quite a bit, but we want to go into the science here.

It's one thing to just kind of say this in a sentence or two and say, I want to say, hmm, I wonder what's the science showing? Is this possibility? It actually is showing quite a bit of this throughout the literature. It's not just a basic hypothesis of one researcher somewhere, some conspiracy theorists. So what are you talking about? IgG4, these are immunoglobulins, and these are just antibodies. They're the most basic, abundant, and common form our immune system comes in. They're in the blood, the lymphatic system, cerebral spinal fluid, and there are classes of these, IGG 1 through 4, and they're the workhorses of our immune system. They're the ones that do the job. And so we look at the paper as early as 2022, we started seeing papers like this. They're calling

this a class switch towards non-inflammatory IgG isotopes after repeated SARS-CoV-2MRNA vaccination. Now it says in here, shortly after the first or second MRNA vaccine dose, the IGG response mainly consists of the pro-inflammatory isotopes, IG1 and IGG3. This is good and is driven by T-helper TH-T-H1 cells. Here, we report that several months after the second vaccination, SARS-CoB2-specific antibodies were increasingly composed of non-inflammatory IGG-2, and particularly IGG-4, which were further boosted by a third MRNA vaccination and our SARS-CoV2 variant breakthrough infections.

You know, those infections you're not supposed to get because you got the vaccine. That's the breakthrough. So we don't want IGG4 switch, that class switch. You do not want that. The IgG4, the immunoglobin, do not have a big potential for immune activation. They only make up about 5% of all of that class of antibodies. They're very subset class. They usually deal with like allergic responses and things like that.

So you don't want that out of whack. You don't want that to supercharge. And why is that a problem? Well, we had Dr. William Macchus on our show talking about... Do we know what percent? And as you say in the body that we want, I mean, is IGG4 always there? I mean, when we say it's just a small part of it, do they have a number on that? Yeah, and healthy people, it's about 5%.

A 5% of your advisor IGG4, the rest are IGG1 and IG3. Yeah, one is one of the most common, one and two. Three makes up a smaller subsection, and then five is the smallest. So that's the one you really want to keep at bay, if you will. That's the balance. and it's kind of like the gut biome, you want these imbalance. So Dr. William Macchus went on the show. He spoke to you and he said this.

Take a listen. Okay. The problem with rolling out this technology, this lipid nanoparticle, MRNA technology with these COVID vaccines, was that there were no modifications to the lipid nanoparticles, and they told us that it would stay in the arm, and this goes systemic. And I think that really is where all the injuries,

vaccine injuries that we're seeing stem from, including the cancers, is that this goes systemic, and then you've got tremendous effects on the immune system. You know, another mechanism, possible mechanism of cancer arising is this what we call antibody shift, this IGG4 antibody shift. And that, again, is a feature of our immune system where if you're getting repeatedly exposed to the same antigen, then your body starts to produce a different kind of antibody called IGG4. That actually gives you tolerance to that antigen. So it kind of gives up on killing it. It's just like I just want to live and let live.

I'm just going to let it hang out in the body now and not fight anymore. Exactly. So another discovery a few months ago, there was a discovery that if you've had two COVID vaccines, you start to produce a little bit of this new antibody, this IGG4. But if you've had three vaccines, if you had the booster shot,

your IGG4 levels go up 500 fold. Wow. And then suddenly it goes from 0.04% to 20% of the antibodies you're producing. And that shifts your immune system completely. You're not producing IGG 1 and 3 anymore. And these are the antibodies that actually handle the viral infections, but they also handle cancer surveillance.

So you're more likely now to get infected, not just with COVID-19. So you see people who've had their booster shot, three vaccines, four vaccines, five vaccines, they keep getting reinfected with COVID-19 over and over. Or they get sick very often with influenza. But you're also reducing cancer surveillance as well because you don't have those IGG 1 and 3 anymore. So you're impairing cancer surveillance.

That could be another mechanism by which all these turbo cancers are arising in people who've had three or more shots. So it's downregulating the whole immune system. So not just downregulating for seeing COVID, but as Brett seems to be hypothesizing, it's why we're seeing all these crazy West Nile outbreaks and things because people just things because people just have weakened immune system that's just making them vulnerable. We're seeing the turbo cancers like crazy. It's wild just to think, Jeffrey, that that was almost exactly a year ago that we had Dr. MacKiss on.

And it was mind-blowing when he said it. But as we get more signs, you see Brett, and it all starts coming together, you just start seeing this horrific, this horrific outcome worldwide. and they are still just the kids and the people and the bam, bam, bam, bam. What is this world going to look like? I don't know, but I think this is where science could really step up and is stepping up where people are communicating in kind of non-traditional formats on podcasts, on things like that, and not taking to the corporate media with this message.

Because corporate media probably won't even relay this message. And experts and regulatory agencies won't. carry this message as well, but this is where this is where this message can go and can live and researchers can do this. And Dr. Maccas is a co-author on this paper where he explains, he shows a lot of the evidence and the mechanisms that this may be happening. And people can look at this paper. This is in 2023, just a year ago, and IgG4 antibodies induced by repeat vaccination, talking about immune intolerance. And it says, overall, there are three critical factors determining the class switch to IgG4 antibodies, excessive antigen

concentration, repeated vaccination, and the type of vaccine used. Unfortunately, the COVID vaccine checks off all those boxes. Then he goes on to say, however, emerging evidence suggests that the reported increase in IGG4 levels detected after repeated vaccination with the mRNA vaccine may not be a protective mechanism. Rather, it constitutes an immune tolerance mechanism to the spike protein that could promote unopposed SARS-CoV2 infection and replication by suppressing natural antiviral responses. Not a good thing. And we saw this in the HIV vaccine trials. Someone put together, a substack author put together looking at all of the vaccine trials about class switching to the IGG4. Lessons learned, they call it, from the failed HIV

vaccine trials. Wow. And they write, antibodies are not a correlative immunity, but studies have shown that the presence of relatively low levels of IGG4 can cause impaired FC mediated effector functionality. It's a big word. That just is kind of like the business end when these antibodies start to kill the cells. That's the complex that does that. B-cell imprinting may be implicated and the effects appeared to persist for at least six to eight years. So that B-cell imprinting is basically focusing on just one antigen. So you get the COVID virus and it mutates, well, they can't really see that. Your system can't see that. It's imprinting on just the one you've been printed it with, with the vaccine. So they're saying those are two problems they saw in the HIV trials, but it

goes on and say this. The recommendation, he writes, after looking at all this according to these studies boosting more than three to four times is not recommended and the gap between boosters should be one to two years minimum to minimize the risk of class switching and imprinting so these are kind of the hypothetical well this is what we've seen this may be happening like this but now we're starting to see case studies so we're starting to see that the first kind of crop of this this new phenomenon if you will and i'm going through these are just a couple But we could spend probably an hour going through these titles and looking at these. Here's one, IGG4-related disease emerging after COVID-19-MRNA vaccination.

There's another one, IG-4-related membranous nephropathy after COVID-19 vaccination. A case report. Another one, relapse of IGG-4-related nephritis following MRNA COVID-19 vaccine. Oh, my God. And acute liver injury and IGG-4-related autoimmune pancreatitis following MRI vaccine. So again, you're seeing when this hyperreaction, this allergic autoimmune reaction, it does target, it seems to target the organs in this IGG response. So you're seeing these, these organ systems that are being targeted.

But it's not just that. You know, we're talking about the vaccine has been given to stop the spread. You know, you're not going to get the virus. You won't get sick if you get this. But even articles like this is Epac Times, new science shows vaccine help. Vaccines help Omicron spread. So you're not going to be, these new variants are not going to be recognized if you're downgrading this immune system, if you're imprinting on this one antigen.

And that's what was shown in the Cleveland Clinic study of just this year, looking at the workers at the Cleveland Clinic that were taking part in this study, looking at the effectiveness of last year's formulation that they call it the 2023, 2024 formulation. I think that was a booster six, if you're counting, but it says conclusions. The 2023, 24 formulated COVID-19 vaccine given to working-age adults afforded a low-level of protection against the JN.1 lineage of SARS-CoV2, but a higher number of prior vaccine doses was associated with a higher risk of COVID-19. So there you go. And it goes on and says consistent with similar findings in many prior studies, a higher number

of prior vaccine doses was associated with a higher risk of COVID-19. The exact reason for this finding is not clear. Of course, they don't go into the IGG in this, but it definitely explains that. And it says, it is possible that this may be related to the fact that vaccine-induced immunity is weaker and less durable, the natural immunity. We've known that since the beginning. But there's a lot of people that are kind of trying to sidestep this idea of, what if if it really downregulated the immune system of an unknown amount of people in the United States. I mean, it's really, I mean, we're sitting here thinking, you know, almost everyone in the world. Like, how much of the country got three vaccines, about 50, 60 percent maybe somewhere in that zone?

To think that all these people, and if they keep going, they're raising their risk of becoming a, you know, a totally deficient immune system. An immune system incapable of fighting off cancer or any other disease. We're not talking about tiny numbers. We're not talking about somebody that took a drug that, you know, a thousand people got because they had a rare disease. They gave this thing to everybody and they're still giving it to more and more people every single day, knowing, as Brett pointed out, knowing that the vaccine is doing the exact opposite of anything you would ever want it to do, which is lowering your immune system

to be able to fight anything you're coming in contact with now in the world. Right. And so yet still, we have the new formulation of the COVID vaccine has just been released. It's being marketed. We're seeing headlines about it as kids go back to school. And the CDC is recommending it to infants. Here's the CDC's actual schedule from zero to 15 months, birth to 15 months. And you can see here at six months, as early as six months, they start recommending right at there on the bottom right, one or more doses of the updated COVID vaccine form. You can get that at six months, nine months, 12 months, wherever you want to get that. If you're a child or a parent, you give it to your child, that's what they're recommending. And so this is the insanity here of what, it's so important to not rely on five, four or five year old information saying safe and effective, stops COVID in 95% of the cases.

This is new information the CDC has not folded into the recommendations, clearly. And guaranteed these studies they're doing around adults. We have no idea how quickly you could downregulate a child's immune system. You imagine welcome to the world. Let's destroy your immune system and see how you do. What is that generation of kids going to do? And then you think about these dystopian movies, you know, handmade tail and things where nobody can give birth or nobody, you know,

you can't have a child that can stay alive. It can't seem to fight any disease. And then what happens to diseases that are inside of people that they have no immune system fighting it. So it just multiplies. They just pass it on to everybody. else. So even those that didn't get the vaccine, you've got these walking incubators for, you know, virus mutation. It's outrageous. It's outrageous that nobody is, nobody inside the government currently right now is throwing up a red flag. They're doing the opposite. It just

Wall Street ahead.