The Highwire with Del Bigtree - WHAT IS DR. MARIK’S LIFE-SAVING PROTOCOL FOR TREATING SEPSIS?
Episode Date: October 6, 2022World-renowned critical care specialist Dr. Paul Marik outlines his life-saving, cheap, and safe protocol for treating sepsis in the hospital, the leading cause of death in the world.#PaulMarikMD #FLC...CC #Sepsis #HATProtocolBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.
Transcript
Discussion (0)
It's actually not complicated. I think the most important concept is early treatment, because as we said,
sepsis is very time sensitive and you don't want to delay. So what we recommend is that you start
immediately in the ED, emergency department. So if you think a patient is septic and you're going to
give them antibiotics, then I would start them on the protocol. And if it turns out that they don't have
sapsis, well, you've lost nothing, but if you've missed it, you've missed that window of opportunity.
Okay.
And I think that's really the message for doctors is that this is time sensitive.
You don't need to do a whole host of special tests.
So what you need to do is treat them early.
And vitamin C is very simple to give.
The pharmacy can prepare it very simply.
So what are the dosages?
Yeah.
So what you want to do is the vitamin C is the most important out of the whole cocktail,
and you want to start this early.
So the dose is 1.5 grams of vitamin C has to be given intravenously in a little money bag,
you know, infused over 20 minutes.
Okay.
They can start that in the emergency department or they can start that immediately in the IC.
Now, is that something every hospital has in its, like, is that around?
Like if I ask for vitamin C, the hospital has that?
There's no reason that a hospital shouldn't have intravenous vitamin C.
It used to be used for intravenous nutrition, but now,
it's quite commonly used and there's no reason a hospital can't get hold of intravenous
vitamin C and have it on their formulary.
Okay.
And so they should have it available, they should have it in the emergency department.
So it's timely administration is really important.
One of the answers is that if treatment is delayed, do you need a higher dose?
And that question I really count answer, we need to do more studies.
But what I can tell you is that if it's, you know, if patients are you know, if you know,
come in early and they treat it early when they come to the emergency department, 1.5 grams
every six hours is what works.
And then we combine that with thiamine, 200 milligrams intravenously every 12 hours.
And the thiamine, I originally added it because I thought it would limit so-called toxicity
of vitamin C.
That was somewhat erroneous.
And thiamine is very good for sepsis.
And then the third piece is hydrochortosone.
This is a critical steroid, which is often used for sepsis.
It downregulates the inflammation.
It works very well with vitamin C.
And so the dose is 50 milligrams every six hours.
So this is not a complicated protocol.
You give early antibiotics, which is the key to treatment,
together with early institution of this protocol.
It's very safe, it's easy to administer.
And, you know, it should become more widely available.
available.
