The Highwire with Del Bigtree - WHY ARE MOST CHILDREN & ADULTS SAFE FROM COVID

Episode Date: December 23, 2021

World-renowned virologist, Geert Vanden Bossche, explains how innate antibodies differ from naturally acquired antibodies, thereby protecting children and healthy adults from developing serious disease associated with Covid-19.Get the Facts:https://www.frontiersin.org/articles/10.3389/fimmu.2020.02139/fullhttps://www.frontiersin.org/articles/10.3389/fimmu.2017.00872/fullhttps://www.nih.gov/news-events/nih-research-matters/lasting-immunity-found-after-recovery-covid-19?fbclid=IwAR2WENPwM1tZfnM7lNrFNAT6zkdxGieo1i9Ay5NsCEzE6MSDoOOk8qlxGrU%20https://www.nih.gov/news-events/nih-research-matters/lasting-immunity-found-after-recovery-covid-19?fbclid=IwAR2WENPwM1tZfnM7lNrFNAT6zkdxGieo1i9Ay5NsCEzE6MSDoOOk8qlxGrU#GetFactsinated #GVB #InnateAntibodies #Covid19Become a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.

What we call innate immunity very often and I'm very often talking about innate antibodies in contrast to the naturally acquired antibodies the innate antibodies these are pre-existing antibodies that are already so to say pre-primed that you have at birth already not as a result of antigen experience A newborn all of a sudden gets confronted with a number of pathogens. You know, the newborn cannot have all these antibodies read because it has never seen these pathogens. So there is, this is providing them with a good start. The innate antibodies were found in every vertebrate species,

also to tell you how important they are from an evolutionary viewpoint that you find them in all vertebrate species. So this is something that we have been completely neglecting and these are basically the antibodies that protect all these young children and people in good health from a disease that is therefore, that is therefore not a childhood disease, right? SARS-CoV-2. So the cells that generate those innate antibodies, we call them B-1 cells. It is a particular type of B cells, which is different from the B cells that generate the naturally acquired antibodies, the naturally acquired antibodies or antigen-specific, first of all, they do have a high affinity for that particular antigen and they are long-lived and they are typically acquired when we talk for example about SARS and yes and other infectious diseases they are

typically acquired once you have gotten the disease and you recovered from the disease and they have high long longevity, so even if they disappear, they generate immunological memory. And because they generate immunological memory, they can be recalled very, very rapidly. So that is also some misunderstanding. Many people are worried because their antibodies have disappeared in their blood. They should know that as soon as their body sees the antigen again, or is re-exposed to the virus, that within no time, because there are memory cells, these memory cells

will again start to produce these naturally acquired antibodies that then will protect them.