The Weirdest Thing I Learned This Week - Ask Us Anything: Can you boost your immune system?
Episode Date: March 16, 2021Check out the first episode of Ask Us Anything, a brand new podcast from the editors of Popular Science! Claire and Jess dive into whether you can boost your immune system, giving it ninja-like capabi...lities to vanquish any infectious critter that crosses its path. Click here to subscribe to Ask Us Anything's feed! https://podcasts.apple.com/us/podcast/ask-us-anything-by-popular-science/id1556759897 Ask Us Anything is a bite-sized show that answers your most outlandish, mind-burning questions—from what the universe is made of to why not everyone can touch their toes. If you like The Weirdest Thing I Learned This Week, we promise you’ll love Ask Us Anything—and you’ll hear a few familiar voices on it, too! Check out new episodes of Ask Us Anything every Tuesday and Thursday wherever you get your podcasts. -- Follow AUA on Twitter: https://twitter.com/AskPopSciPod Hosted by Claire Maldarelli: https://twitter.com/camaldarelli Produced by Jess Boddy: https://twitter.com/JessicaBoddy Music by Billy Cadden: https://open.spotify.com/artist/6LqT4DCuAXlBzX8XlNy4Wq Art by Katie Belloff: https://twitter.com/Katie_Bellz --- Send in a voice message: https://anchor.fm/popular-science/message Support this podcast: https://anchor.fm/popular-science/support Learn more about your ad choices. Visit podcastchoices.com/adchoices
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Hello, welcome to ask us anything where popular science answers your most outlandish,
mind-burning questions from what the universe is made of to why not everyone can
touch their toes.
I'm your host, Claire Maldarelli.
And I'm your producer, Just Bodie.
Let's dive into today's question.
question. Yeah. So this week's question is, can I boost my immune system? Oh, right. Yes. Everyone wants to be
that person who never gets sick. I think of myself as someone who rarely gets colds, but don't want to brag.
You definitely know at least one of those people. The person in that office, oh my gosh, remember office life.
Yeah, barely. Right. Who somehow skips the bug that's traveling from cubicle to
cubicle or the one that doesn't come down with a cold even when the entire family falls victim.
And considering we're still in the throes of a pretty severe, I would say, viral pandemic.
Yeah, pretty severe, just a little.
Yeah, yeah.
Shoring up that kind of apparent super immunity feels even more imperative.
So it's an enticing idea, perform certain activities or eat in certain things, and perhaps
you could become an illness fighting ninja.
I love the idea of being a ninja in any form.
Yeah.
But, okay, unfortunately, it's not exactly how the immune system works.
But there is hope.
More on that in a minute.
Welcome back.
Today, we're looking into whether you can boost your immune system.
The short answer?
Not really.
Oh, nuts.
I knew it was too good to be true.
Yes, Jess, but not all hope is lost.
Okay, so keep listening.
It's worth the weight.
Okay, okay.
There are things you can do to help your immune system do its best work, fighting a nasty illness, whether it's COVID-19 or the common colds.
But before we get into any of that, it's important to understand how our body's natural defenses work.
Our immune systems are actually two different sets of responses, the innate and adaptive.
The innate immune system is made up of various proteins and cells that activate as a response to any type of bodily injury or illness, even a scrape to the leg.
But the latter, the adaptive immune system is far more precise. When you get a cold, the flu, or even the novel coronavirus, cells within your adaptive immune system rush out to identify exactly what that sickness is. Once they do, they cleverly design new immune cells, including ones called antibodies, to find and kill that infection. Those protective cells remain in the body, so when you come in contact with that virus, bacteria, or other infectious agent again,
your immune system knows exactly what to do.
That's why it's generally incredibly rare to get the exact same infection twice.
This memory mechanism is very cool and convenient.
It's also why vaccines work so well.
The vaccine can be a tiny bit of virus or bacteria, usually a dead version,
or pieces of genetic material like MRNA,
that instruct the body to create a component of the infectious agent that the body will recognize,
such as those spiky proteins on the SARS-CoV-2, the virus that causes COVID-19.
Once presented with that infectious bit, your immune system builds cells that can kill the intruder.
After that, the system creates what's called memory T cells, which remember the infections
so that when you come in contact with it, your body knows exactly how to kill it.
But the key component here is the sequence of events.
First, come in contact with the virus, then develop immunity to it.
Unfortunately, as you can see, it just can't work the other way around.
So the idea of quote-unquote boosting the immune system until it can fight off any infection
just doesn't make sense.
There are countless cold viruses, known as rhinoviruses, and various forms of the flu,
which is a big reason why the flu vaccine isn't always as effective as doctors hope.
There's no way to train the body to fight all of them.
Yeah, that would really make life a lot easier if we could, I guess.
Is there anything, like, at all that we can do?
Yes.
So your innate and adaptive immune system both need a certain amount of cells to work properly.
If you want to give yourself a fighting chance, figuring out the best way to activate the right number of immune cells is key.
Oh, so how do you do that?
That's the million dollar question.
We don't have the tools to boost any one person's production of one type of immune cell versus another just at the draw.
of a hat. And even if we did have that ability, it wouldn't necessarily benefit us.
Having an increased number of a certain type of immune cell is actually not a good idea if there's
no immediate infection. In fact, it could potentially lean to too much inflammation in the body,
which could eventually hurt your organs or even lead to an autoimmune disease. Really, there's just
no need for it. If you haven't been infected with, say, the common cold, then carrying around a ton of
antibodies against that one virus is doing you more harm than good. You don't want an immune system
in a constant state of activity, since that takes a toll on your body. What you really want is one that can
act quickly and effectively when an infection hits. Okay, okay, I got you. So how then do I make my
immune system chill when I don't need it, but powerful and fast acting when I do need it?
Yes, Jess. Great question. Oh, thank you. Thank you. Always asking the good questions here.
ask us anything. There are the obvious factors, like getting the proper amount of sleep. That's
eight hours for adults. Yes, eight hours. We'll get into that on a later episode, I promise.
Surprisingly, or maybe unsurprisingly, sleep affects the immune system in a number of ways.
Some studies show that when you are sick, sleep might help send immune cells to the lymph nodes,
which is where they go to work multiplying in bulk. And sleep is important for creating the right
immune cells to fight off disease. For example, in one study, researchers gave participants the
hepatitis A vaccine, and that night they sent half the study participants to bed for a full
night sleep and had the other half pull in all-nighter. Four weeks later, on average, the ones that
slept regularly on that first night had twice the number of antibodies to the hepatitis
infection than the ones that didn't get their disease. Oh, okay, so what about food then? Can I just
like chug green juice. Green juice. I feel like that's the answer to so many things. Sort of. So in
terms of nutrition, eating a well-balanced diet will keep your immune system balanced too.
On a macro-nutrient front, studies show that protein might be particularly important for a strong
immune system. Protein is key to forming every cell in the body, immune ones included. More specifically,
protein contains an amino acid called L-Arginine, which immunologists suspect helps generate specific
types of T cells called helper T's. These cells show the rest of the immune system what the virus
looks like so that it can generate specific cells to fight it. Consuming protein with L. Arginine,
which is found in red meat, poultry, fish, and dairy, according to Megan Mayer, director of science
communication at the International Food Information Council, which is a nonprofit organization focused on
providing science-backed nutrition research to the public, is a way to ensure your body is making
the right amount of T cells. And consuming enough protein overall is a way to ensure you'll have
plenty of T cells in the event you are confronted with an infectious disease. Things like your
height, weight, and how much you exercise all influence how much protein your body needs. But the average person
require 0.36 grams per pound of body weight. So a good way to get a rough estimate of how much protein
you need is to multiply 0.36 by your weight. So, for example, someone weighing 160 pounds would need
about 58 grams of protein per day. For reference, a chicken leg is about 12.4 grams of protein,
or one-fifth of that person's daily needs. Oh, so you just need like five chicken legs and you're good.
Yeah, five chicken legs a day.
It keeps the doctor away.
Okay.
But on the micronutrient scale, there are also a few standouts.
Perhaps the most well studied is zinc.
A few very good double-blind placebo-controlled trials, which is the quote-unquote gold standard
of scientific research.
Using zinc lozenges at the start of a common cold reduce the duration and severity of the infection.
And a comprehensive review of nearly 20 trials and more than 1,700 participants
also showed that the element did decrease symptom duration of the common cold, though only by a day.
And researchers do have an idea of how it works. Due to their unique shapes, zinc atoms are able to
literally attach themselves to the rhinovirus and prevent it from further infecting the person.
So eating foods with the element on a regular basis, which include red meat, seafood, and whole
grains, as well of some fortified foods like breakfast cereals, and taking zinc supplements can
potentially prevent and decrease the severity of a common cold infection, though it is no magic
bullet and it will certainly not get rid of the cold entirely. Luckily, other micronutrients can help too.
For example, one study out of the British Medical Journal found that vitamin D supplements
reduce the risk of respiratory infections, and another done on school-age children in Japan found
that vitamin D reduced the risk of influenza. A number of recent studies have linked low vitamin D
levels with severe COVID-19. But more studies are absolutely needed to make any definitive conclusions
or recommendations. So the bottom line is that sleeping well and eating a wide variety of fruits,
vegetables, and proteins will help your body maintain a healthy and stable immune system,
one that can jump into action as soon as you need it. And of course, get your flu shot and COVID-19
vaccine when it becomes available to you. You don't have to tell you. You don't have to tell you.
me twice. Thanks, Claire. My pleasure.
Got a question for the editors at Popular Science? Send an email to Ask at Popsai.com.
We'll be back soon to answer more questions. Ask Us Anything is produced by the editors of
Popular Science. This episode was written and reported by me, Claire Maldarelli, with additional
editing and audio engineering by Jess Bodie. Big thanks to Billy Cadden for writing our theme
song and to Katie Belloff for creating our logo. If you like our show,
Consider rating it on Apple Podcasts and leaving a review.
It helps us a lot.
For more Popsai audio content, be sure to check out our sibling podcast,
The Weirdest Thing I Learn This Week.
I'm Claire Maldarelli.
Thanks for listening.
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