Weird Medicine: The Podcast - 379 - Ebola Vaccine and CBD Autism Research

Episode Date: October 24, 2019

Dr Steve, Dr Scott, and Cody from Indighost discuss tennis elbow, Ebola, CBD research in autism spectrum disorder, chemo induced neuropathy and more. PLEASE VISIT: stuff.doctorsteve.com (for all your online shopping needs!) simplyherbals.net (Dr Scott’s nasal rinse is here!) noom.doctorsteve.com (lose weight, gain you-know-what) tweakedaudio.com offer code “FLUID” (best CS anywhere) premium.doctorsteve.com (all this can be yours!) Learn more about your ad choices. Visit podcastchoices.com/adchoices

You're listening to Weird Medicine with Dr. Steve on the Riotcast Network, riotcast.com. I need to touch it. Yo-ho-ho-ho-ho. In the garretail. I've got diphtheria crushing my esophagus. I've got Tobolabovir stripping from my nose. I've got the leprosy of the heartbound, exacerbating my impetable woes. I want to take my brain now.

Blast with the wave, an ultrasonic, ecographic, and a pulsating shave. I want a magic pill. All my ailments, the health equivalent of citizen cane. And if I don't get it now in the tablet, I think I'm doomed, then I'll have to go insane. I want a requiem for my disease. So I'm paging Dr. Steve. It's weird medicine, the first and still only uncensored medical show in the history of broadcast radio. Now a podcast.

I'm Dr. Steve with my little pal, Dr. Scott, the traditional. Chinese medical practitioner that keeps the alternative medicine wackos at bay and also Cody Gilmer from Indigo's. Check them out at Indy Ghost Band on Twitter or on Spotify. You listen to them. This is a show for people

who'd never listen to a medical show on the radio or the internet. If you've got a question, you're embarrassed to take your regular medical provider. If you can't find an answer anywhere else, give us a call at 347-76-4-3-23. That's 347 Poohead. Visit our website at Dr. Steve.com. podcast, medical news and stuff you can buy or go to our merchandise store at cafe

press.com slash weird medicine. Most importantly, we are not your medical providers. Take everything here with a grain of salt. Don't act on anything you hear on this show without talking over with your doctor, nurse practitioner, physician assistant, pharmacist, chiropractor, acupuncturist, yoga master, physical therapist, clinical laboratory scientist, rock star, registered dietitian or whatever. All right, very good.

So don't forget to check out stuff. Steve.com. The holidays are coming up for all your shopping needs, stuff. Dot,doctrsteve.com. You can just click through at the top to go to Amazon, or you can scroll down and look at all the different products that we've talked about on the show that we either recommend or that we've tried or we've talked about. Also, tweakeda audio.com makes the best stocking stuffers and excellent Hanukkah gifts. Tweakeda Audio.com, the best earbuds for the price on the market and the best customer service anywhere. Use offer code fluid for 33% off. Check out Dr. Scott's website at simplyerbils.net. And if you want to get to your ideal body weight, as I have, for the first time since college, and I'm keeping it off, do noem.

dot, dot, dr. steve.com. It's N-O-O-O-M-N-O-O-M, November, Oscar, Oscar-Mike. dot dr steve.com and if you do that if you want to try it you can try it for two weeks and you get most of the program in those two weeks I mean the most feel of the program which you

don't get is your group and your group counselor but you get a feel for it and if you decide to do it it's just a three months program and you get 20% off so it's a really good deal numbe.com

I cannot recommend this highly enough it worked for me. Now, I've had some people say, eh, I just, you know, it wasn't for me. And that's fine. You get to try it for free. So there's no risk in that regard. So give it a try.

Noom. Dot, Dr.steve.com. If you know anybody that needs it that doesn't listen to this show, turn them on to it, you know, 20% off and two weeks free, you can't beat it. If you're lazy and you want to do your Noom and know how many calories you're eating, try freshly. They deliver fresh prepared meals that make eating right super easy.

I love the cauliflower shell bolognaza. It sounds horrendous. I know if you're not used to this. But I can't tell that that's not pasta, except that it doesn't kill my stomach like pasta does. And it doesn't spike my blood pressure or my blood sugar and all that stuff. So a little, just a modicum of sour cream on there. And it's awesome.

And the steak is really good. and, you know, it's microwaved. So, you know, lower your expectations some in that regard. But there's a lot more food in this than there is in, say, something like a lean cuisine or something. And I think it's less processed and it's better for you. You can use my link to get six dinners for $39 for two weeks. That's $20 off each week. Give it a try and let me know what you think.

That's freshly. That's freshly.com. And then if you want archives of the show, go to premium. dot dr steve.com use the offer code fluid and get half off it's just a buck 99 a month at the worst and or you can go to dr steve.com and look around there's a link where you can pay 30 bucks and get our you know a um a thumb drive with 16 gigs of every podcast that we've ever done since we started at riot cast so check that out as well all right well welcome back cody from your triumphant

southeastern tour. I understand you guys are applying to South by Southwest. Yeah, I just found that out today, actually. So what do you have to do to apply to be on South by Southwest, which would be awesome, by the way. I think you guys would kill.

I think we would do really well as well. I have no idea. Literally came straight from work, and I happened to glance over the message from our singer being the one applying for it. So I will find out very shortly. All right. Listen, there's a kind of.

couple of things that, this is what, look, I don't ask our listeners to do a whole lot of things other than go to like stuff.com and things like that, but for something like one year, P.A. John was in a beer competition, and I put out a tweet, hey, help P.A. John win. You can use your cell phone call this number, and you can do up to 10 votes. And he apparently won by a margin larger than the number of people at the actual... The attendees at the festival. And they knew some shit was up, but, you know, they didn't know what. Because they didn't know who P.A. John was.

Well, nobody knows who he is. But there's a small cadre of people who know, and they came right to help us out. And that was awesome. It was... I said your dedicated listener. It was so much fun. And he and I were just laughing. And I felt like a hero because I got to help out my buddy win the same.

I think he would have won anyway because he, you know, because he's won a bunch since then. So, but it was just fun to see him win by that many. But anyway, I would like to see our listeners. If you don't mind, just get on your Twitter right now and tweet to SX, S.S.W. It's at SX, SX, S.W. and let's and just say that you'd like for at Indie Ghost Band

to play at Southwest by Southwest this year. They don't have to know that you're in you know, England or Czech Republic listening to this

and have no intention of going to South by Southwest. Just let's spam them and see what happens. Y'all are the shit. Now y'all don't know Cody very well but I know Cody. very well and you will come to appreciate him like I do and I'll tell you why I like having him

on the show right now as a sort of a new person that's coming on a more regular basis because he's a fucking hypochondriac. Ah, I tend to be. And that's for a medical show, it gives us something to talk about. So what have we got this week? Well, I don't know if this is a hypochondria moment because I definitely have tend to do this. It really, really does hurt. It does and it will not go away.

Right, right, right. I keep getting it to start to feel a little bit better. Give yourself a bill. And then immediately it goes right back to the same old bunch of bullshit. Okay, well, nobody can see what you're pointing at because you're on the radio. So tell us what happened. Oh, did I not say tendonitis? Well, I don't know.

Tendonitis. You've got lots of tendons in your heart. Like, right below my elbow. I don't know. Would that be considered my elbow, like, right in here? Yeah, sure. Because it's, I'll let someone who's a medical professional describe on where I'm talking about. Okay.

I know my elbow's here. The elbow is the joint between the fore. forearm and the arm itself. So what would be, I guess it'd be in my forearm. You're on the lateral aspect. In other words, the outside part. So you've got lateral and medial. Medial is inside toward the body.

Oh, okay. And lateral will be outside away from the body. So a lateral. And it's right under the place where the little bony prominences in the elbow. Right here. Like if you could put screws in there, that'd be like the Frankenstein joint.

Yeah. So right below that. All right, Scott, take it. I know exactly what you got. Yeah, but in what you're, he's got it's interesting though what really kind of nailed down the diagnosis is he's got one of those typical black elbow braces right that we typically give to people that have a thing called lateral epiconalitis right okay and you've also he's also wearing a wrist brace

with metal with metal um plates in it to to um keep his wrist from rolling back and forth right and keep him from moving his wrist so what you've got is a pretty classic lateral epicontalitis which is also known as tennis elbow. There you go. Oh, okay. Give yourself a bill. I knew tennis elbow. Not to be confused with media lepeconlights with his golfer's elbow, okay?

Oh, so there is a difference. There's a golfer's elbows on the inside. Give yourself a bill. And what that, now the reason you've got the lateral lepecon lines. He gets one of those anytime. He says something correct because it's so unfrequent. It's pretty infrequent. But what you've got, it's an overuse injury, and it's a repetitive use injury.

What's happening is the radius. is in your lower arm, your distal arm, is rotating over the ulna. So the radius you can find by, it's the little bone on the thumb side. That's how you can remember. Okay. But what happens is it's rolling over the ulna,

which is a little bit larger bone in your lower arm. Mm-hmm. And there's some ligaments and tendons where you're poking there. And almost everybody, if you'll walk your fingers up your arm and bend your elbow, you can follow the crease in your elbow

over to a really sensitive spot where those ligaments and tendons attached, and that's what happens when the muscles start to pull, and when they pull, you get some tension spots in there, and that's just what that is. So it's the epicondial of that bone, which is just where the ligands

and tendons attach, yep. And it's like a hinge, and it's a hinge part. It's a hinge part. It's a hinge joint. And what the reason the, the brace on your wrist actually helps is because what it stopped is that rotation of your wrist and rotating

the wrist, so it's not rotating your elbow. So a couple things. I tell people all the time. Anytime you pick anything up and you've got a tendonitis in your elbow, don't pick up anything with your thumb pointed in, or as we say meadly. In other words, the palm of your hand down and the upper part of your hand facing up. Because when you do that, all of that load goes on your elbow. Okay. So think about a backhand of tennis thing. Same thing. So none of this. Yeah, so doing that. So anytime you're doing this, backhand in tennis is a really difficult stress

because all the load goes right there so if you'll turn your hand where your thumb is pointing up like you're giving somebody a thumbs up now what you're doing is all of the load is going to your bicep and takes the tension off your elbow so when you're at work

and you're flipping things or chopping things or whatever if you can just kind of keep your elbow down to your side and keep your thumb up that'll take away some of the pain that's super handy and then when you're jumping around

the stage and doing crazy stuff with the guitar. Does it hurt when you're playing? That's what interesting. Not all the time, but if you're a keyboard, if your tenting out been banging on a keyboard. It would.

Yeah, it didn't hurt a few practices, but I got to one show at about three quarters of the way through. I was about done with the show because it was extremely painful. Well, part of that, Dr. Steve, is most likely what he's got now is when you're playing guitar, if you get your

elbow kind of fanned out and your wrist tucked in, to play, that's just too much tension. If you'll relax the elbow with some and try to keep your wrist kind of flat wire playing. That's awesome. It's just a positional thing. That makes a lot of sense.

We see a lot of times. Now, the tennis elbow brace puts a different fulcrum on there. So what that's supposed to do, it should be tight enough, so that's putting compression on that tendon. So now when you

flex those muscles, the tension will go to the part of that band that is, you know, the farthest down the arm. Yeah, the band actually acts as the ligament or tendon now. Right. And so it's basically protecting the ligament that is, or the tendon, that is injured,

and it's creating a fulcrum so that all the pressure is going to the end of that band. Now, sometimes that's all you need to do. Sometimes that's all you need to do. But if it doesn't work, of course, always ice. I've been icing the hell out of it. And when I say ice, you know, cold compresses, you don't want to put ice directly on it. But what would happen if I put ice directly on it? Well, you can get burn.

You can get freezer burn. You know, because remember, ice can be below 32 degrees, right? It can be infinitely cold. Oh, yeah. Well, I've been putting ice directly on it for quite a while. So just do this, though. You know, we like frozen peas. If you're not just going to go out and buy a cold pack, frozen peas and wrap that in like a paper towel and put that on there.

so that there's a little bit of thermal insulation and the cold. It doesn't get so cold. And then you can just throw those peas back in the freezer when they warm up and just don't use them to eat once they've been frozen and refrozen and they suck. But, you know, a bag of peas cost $0.39. And then if none of this works where you're taking the pressure off of it and you're using the brace and you're icing it and taking maybe – but you have rectal bleeding, though, right?

So you don't want to be taking a lot of ibuprofen. So anti-inflammatory is not the greatest idea for you. But what I could do is inject that sucker. And we could do that live on the show sometime and we'll get Scott to videotape. Oh, that sounds fun. And I can make the pain completely go away within about 30 seconds because you know what a tracer bullet is, right? Yeah. Okay.

So why do you put tracers in like a machine gun? See the trajectory? Right. So particularly at night, but a day, you can see where the hell you're shooting, right? So it's like every 10th bullet or something like that. You know, and so what it really is is just confirming that your aim is right, okay? Yeah. So think of it that way.

So when we do a cortisone injection, we'll add a short acting, and I always add a long-acting anesthetic as well. And when I do that, yeah, it makes it feel better right away, but what I'm really doing is making sure that the cortisone's going in the right place. So it's acting like a tracer bullet. When I shoot up your elbow with this stuff and you go, oh, the pain's totally gone afterward,

then I know I put the cortisone in the right place. Oh, okay. And I always just put, because I'm a, you know, I deal with chronic pain, I put the real long-acting anesthetic in there just to give people some relief for a little while. Can we please do this? Yeah.

I've literally been dealing with this for like three months. Oh, yeah. I may even have the stuff, so we'll see. Hell yeah. If not, what you could do is come to my office. I won't be, well, anyway, we'll talk about it. But yeah, we could do it. But I wouldn't mind.

I'd love to do it on the show. That'd be easy. And the other thing is if you don't, if you've had around the steroids and it helped for a short period of time and then it kind of comes back. That's kind of when people tend to come see me. And we actually do the acupuncture in the elbow in the forearm and the upper arm

just to take the tension off of the elbow. Hey, but real quickly, the last thing, Dr. Steve, I'll tell you, well, a lot of people I see Cody do is they wear that elbow brace too low. And he's right, it takes the tension off the tendon, but if you don't wear it up high enough, I mean, I'm talking about right in the crease, it doesn't stop that rotation of the elbow.

Yeah, that's something I was really questioning about Because honestly, I haven't had it. They just hand them to. Yeah, and you just slap it on there. And you just slap it on. You want that as high in your end, it goes up right in the elbow crease. Right in the crease? And it'll stop the, almost to the crease, yep.

Okay. Yeah. So like right here? You want the upper part of the brace at the base of the crease. Okay. Yes. You want to just kind of right at the other right there. I see these people with humoral fractures.

You know, like if they're not going to fix it for whatever reason. Oh, yeah. That's where it pains at. Right. Oh, boy. Right. When I talk about a humoral fracture, I'm talking about the long bone of the arm, not the forearm.

And up at the shoulder, you can break that. Yep. You know, and you get this humoral fracture, and they will give people a thing called a sling and swath. It's a sling, but then the swath goes all the way around your body, and what it's supposed to do is hold that arm immobile against your chest. So you cannot move it. Right.

And I just see people, and they just throw them at them, and they don't know how to do it. They just take that big piece of fabric and throw it away, and they just got a sling, and they're just moving their arm around. it doesn't do anything. Well, I kind of felt that way with this brace specifically because I knew I wasn't, I'm actually glad you answered that because I had, I knew I wasn't putting it on correctly, but I've been just shooting in the dark essentially. Of course.

Trying to figure it out. Of course. Well, everybody is. Hell, yeah. I'm excited now. Okay, we'll do that. We can get you feeling better. Yeah, it's stairwood and a little long acting thing that'll make it feel much better quick.

Ooh, that sounds very pleasant. I'm all about it. All right. Okay, so at Indie Ghost Band, I-N-D-I-G-H-O-S-T band. There's no E-N-E-N-E in there. It's Indie Ghost, right? Indie Ghost Band. Wait, an E-N- what?

There's an E-N-The. Yeah, but there's no the in your Twitter handle. It's just Indie Ghost Band. Let me double check. I'm pretty sure. I'm going to double check. I can find that out real quick, but I don't want to steer people wrong here. Nope.

I'm doing it right now. I don't even have a Twitter. I just use the Indigose Twitter. No, Indy Ghost Band. There's no the. Give me a minute. That's you. It is just Indigoast.

Right. But it's not I-N-D-I-E-Ghost. It's Indy with an I-Ghost band, all one word. Indie Ghost Band. As usual, Dr. Steve is correct. There you go Give yourself a bill You're learning

I will I'll tweet that out At the end of the show today And we'll get that shit going Hell yeah Spam the hell out of them I appreciate you guys And you never know

But All right Anything else We got anything else Is that it Scott you got anything No I think it's good Okay

All right Let me get some Let's do some questions Number one thing Don't take advice From some asshole on the radio All right, sounds good. Let's see here.

Well. Hey, Dr. Steve, if you're doing well and got the real estate MLS listings I sent you. I just finishing up updating the Ebola map. I had an Ebola patient today at Washington, D.C. Okay, so this is our buddy from the Ebola map. I think it's just Ebola map.com

Check that out, Scott. See what his thing is. And he loves to talk about Ebola. But the reason I played this was not because there was a patient in Washington, D.C.

If there was. I mean, he said there was. Who am I to say there wasn't? But this is from October 18th from the World Health Organization. Not some fly-by-night BS organization. organization, but in fact, the World Health Organization, and the title is Major Milestone for WHO-supported Ebola vaccine.

All right, the World Health Organization welcomes the European Medicines Agency announcement, recommending a conditional marketing authorization for the RVSV. hyphen Zbob, Z-E-B-O-V-G-P vaccine, which has been shown effective in protecting people from the Ebola virus. Today's announcement by the EMA, why is Europe up front on this? Why aren't we? The European agency responsible for the scientific evaluation of medicines developed by pharmaceutical companies is a key step before the European Commission decision on licensing. In parallel, WHO, that's the World Health Organization,

will move toward pre-qualification of the vaccine. The conditional authorization of the world's first Ebola vaccine is a triumph for public health and a testimony to the unprecedented collaboration between scores of experts worldwide, said Dr. Tedros, Adanum, the WHO, Director, General, try to pronounce this, G-H-E-B-R-E-Y-E-S-U-S-U-G-R-E-S-U-G-R-E-S-U-G-R-E-S-E-E-R-E-S-E-E-O-T-I. Yes, so this was George Bernard Shaw, was showing how ridiculous English is,

and he showed how you can spell fish, G-H-O-T-I-I-E. So you're using the G-H-O-T-I-T-I-F, that's F-Sound, right? The O from women, and the T-I from, like, nation. So, G-H-O-T-I, fish. What the hell? I still, I'm never going to get that. Well, sure, okay. No, I get it, but I'm not going to get it.

Yep, that's why you're here, my brother. Indeed. It's just an endless. Okay, anyway. Oh, Lord. Never-ending supply of goodness with Cody here for a while. Okay, let's see here. The past five years, WHO has convened experts to review the evidence on various Ebola vaccine candidates,

informed policy recommendations, and mobilized a multilateral coalition to accelerate clinical valuations. Now, you know, when they do something like this, yeah, okay, we got an Ebola vaccine. That's cool. Well, what about the next virus? Well, the neat thing is that now they have an accelerated mechanism. for developing the next vaccine that we need for some damn thing, you know, if these, the sky is falling infectious disease predictions about the glaciers melting where we're going to have these 100,000-year-old viruses that the Earth hasn't seen that are going to, you know, come back, which, by the way, is pretty unlikely because most viruses that we know won't live five minutes outside a host. You know, but say there is some crazy supervirus. We should have a mechanism, at least for convening all these people.

And, you know, vaccine research ain't exactly rocket science. I mean, you're looking at making antibodies to proteins on the virus itself. So you just got to identify the virus proteins that we can create in the lab that will prevent infection. That last part is the trick. And once you do that, you basically have a vaccine. So let me see. The randomized trial for the vaccine began during the West Africa Ebola outbreak in 2015. When no other organization was positioned to run a trial in Guinea during the complex emergency,

the government of Guinea and the WHO took the unusual step to lead the trial. Good for them. A global coalition of funders and researchers provided that critical support required. funders included Canadian government, the Norwegian ministry, the UK government. Where the hell is the United States in this? Behind. Yeah.

Well, I'm a little disappointed by that. The trial was successfully run using an innovative ring vaccine design. Let's see here. Okay, there's eight vaccines undergoing clinical evaluation. Okay, hopefully we're working on one of the other ones that's going to going to even be better than this, but, you know. The announcement will not have an immediate effect on how the vaccine is accessed or administered in the Democratic Republic of the Congo as licensing has not yet occurred, and licensed

doses will only be available in mid-2020. So, yeah, and the current Ebola outbreak in the Democratic Republic of Congo, more than 2,000, God, 236,000 people have been vaccinated. Oh, donated by Merck. Now, look and see if Merck is an American company. Maybe we're doing something right, including more than 60,000 health and frontline workers in that country. In also Uganda, South Sudan, Rwanda, and Burundi. This vaccine has already saved many lives in the current Ebola.

Wouldn't it be nice if this Ebola would just become a thing where people get it? And it'd be great if the vaccine, you know, if you're in an endemic area or an area where it can become an epidemic that they just vaccinate everybody, just like we do smallpox, we still do polio. And it would be really great if it's fast acting so that you can go in to an outbreak and just vaccinate everybody around the person that is suffering from the illness because that's how we got smallpox. We didn't vaccinate everybody in the world to eradicate smallpox. What we did was we went wherever there was a smallpox case and vaccinated everybody around them. And the vaccine was so rapid acting that the virus stopped right there. The other good thing about smallpox is there's no asymptomatic carriers. So if you've got someone that is carrying the disease and giving it to people like typhoid Mary but doesn't have symptoms,

that screws everything up because you can't you don't know who they are so you need a disease that doesn't have any people that can give it without having symptoms at least not for long and Ebola is one of those diseases as far as we know there aren't asymptomatic carriers walking around so there's no way to know no so there is a way to know so there are not asymptomatic carriers meaning there's not people who are showing no outward sign of disease just walking around giving it to all all kinds of random people. Now, they may in the beginning before they show symptoms, but it's a short, short period of time. For a simple guy over here, what is Ebola virus? It's a gnarly. Give yourself a bill. Okay, so. I'm getting it confused with something else.

No, Ebola is this hemorrhagic fever virus that, you know, first emerged on the continent of Africa and is, you know, kills a large. percentage of people that get it. It's nowhere near 100%, but it's large. Let's ask, let's ask A-L-E-X-A, except I changed her name. Echo, what's the mortality rate from Ebola? Here's something I found from the article Ebola virus disease on Wikipedia. Ebola has a high mortality rate among primates. Did that answer your question? It will be kind of. No, not really. Okay, let me see. your feedback.

So the one thing about Ebola, which is kind of unique, is it kills so quickly that it doesn't spread. Kind of like to... Death rate. Oh, well, shoot, I was wrong. I was thinking that its death rate had been over, had been exaggerated, but it's about 90%. So, and it's a member of this philovirus family, and they're real long sort of weird-looking viruses, you know.

And what were you going to say, sorry? No, I was just saying that the one thing about the Ebola virus, which is different from a flu virus, the flu virus is passed on from person to person because it kind of has a long incubation period. Right. It's easy to share, but Ebola blows up fast and kills fast. So it tends to killing groups, you know, of very close proximity. And you're spewing out all kinds of fluids that are. This is not what I'm, okay, I'm getting something.

confused with oh is it is it is it what are you confusing it with this i have herpes yeah you're gonna laugh uh is it is it is it zika virus oh zika zika virus that's the one i was getting confused with yeah okay so similar but not really no i mean zika is just another new virus that we didn't know about until a while ago and that's the one that if pregnant women get it yeah that's the then the babies are born with little tiny heads yeah that's one just you know it was a I do it affected pregnant women, but I did not know tiny heads. Yeah, it's a mosquito-born illness. And, yeah, it makes the heads literally are profoundly small.

Tropical areas and stuff. Are the infants still born or survived? Yes. Just they have tiny heads? Yeah, well, and I don't know how their development is. I would think it's not good. Yeah, it can't be that great. They're developmentally challenged.

Okay, that makes a lot of sense. There should, let's see, Zika, babies. Pretty difficult thing. Let's see what it says. Developmental delays persist in Brazil. Zika babies grow up, yeah. Let's see here. I'm going to have to do some virus research because...

Well, that's what you have us for. Exactly. Okay, a new study published Wednesday in the New England Journal of Medicine reports that a group of Zika babies from Brazil who are being followed to assess their progress. 14% had severe developmental problems. So it's only 14%. They said this was higher than they had security. suggested previously.

These children scored unusually low scores on testing of their cognition, motor, or language skills, or they had visual or hearing impairment. And, yeah. So there you go. Testing was done the second year of life for these young children between the ages of 12 and 18 months. And of the total, 94 of the children underwent imaging. Okay, wait a minute. Six of the children had microcephaly. And we're so profoundly impacted that in essence, the psychological testing could not be conducted.

So it doesn't affect everybody the same way. But, yeah, so Ebola, and Scott's right, that's why we haven't had this sort of worldwide pandemic that everybody thought, because it's really easy to give it to people because of just the huge amounts of fluids that are infectious, including semen is infectious for long, You know, you can get over the illness and still have the philovirus in your semen. And there have been some cases of suspected transmission that way. But there are, it kills people so fast that it tends not to spread like you would think it would. You know, like those science fiction movies where you see the pathogen, you know, working its way across the globe. It just doesn't do that. It kind of cuts itself off.

Yeah. Let me, um, this is my kid calling. Let's see here. Beck, you're on Weird Medicine. Awesome. Can you take me to guitar practice? To guitar at what time? 5.30? Yes. I certainly can, my friend. But I cannot pick you up because I have a board meeting your mother. I'll have to pick you up. Okay, that's fine. Okay, listen to the voice on this kid.

He's got it. Dude, we've got to get you into radio. He's got the voice. All right. Do you have anything to say to your loyal fans? Yeah, that's the problem. All right. See you later, buddy. That's the issue with the whole radio thing.

All right. No, no. At least he knows. Yeah, so this vaccine's very exciting. It would be interesting to see if we can do that sort of treat the cases and treat the people around the cases, all depends on how quickly this vaccine works. So if I shit on you and then 12 hours later, they come and vaccinate you, will it protect you?

If it doesn't, then that technique isn't going to work. They could maybe go out to the community, but it won't protect the people in the family and it won't stop the virus. So in that case, the better strategy is generally going to be to just vaccinate everybody in areas where this is an issue. And we probably can't eradicate it. This is the other issue with this vaccine. Smallpox, the only reservoir that we knew of were humans.

In Ebola, there's probably an animal reservoir somewhere until we figure out where this stuff hides between outbreaks. Bats, you know, wild pigs, who knows. It's hiding somewhere. until we find that out and vaccinate them, we won't be able to get rid of it. You know, in this country, people generally don't die of rabies, but there's still rabies around. We still got to vaccinate our dogs because foxes and bats will still pass the virus around. All right? This is so over my head, but I am fascinating.

Well, that's why we want you here because seriously, if, well, now that's my other. I don't even know. No, this actually helps, you know, it helps us to break it down. Yeah, it helps us to break it down. Liam, you're on Weird Medicine. What's that? I will certainly do so. Thank you.

Thank you. Do you want to say something to your loyal fans on the radio? No. There you go. Runs in the family. Okay, see you, man. Liam used to be on this show all the time. Yes.

Before he grew up, yeah. He did a thing with East Side Dave where they got in this sort of wrestling argument back and forth. You know, hey, shut up, McDonald, you know, and Eastside Dave took it too far. And if you're interested, go back. Go to Dr. Steve.com. You'll have to have a season pass. It's a buck 99. You go to premium.

dot dr steve.com you can get one use offer code fluid it's a buck and then go back I think it's like episode number 10 but it's Liam versus east side Dave and the whole saga is on there I'm going to look that up it was pretty entertaining until

Dave went too far which Dave is want to do but that's fine that's why we love him all right let's see what else we got here I'm like scared of viruses now. Hey, Dr. Steve.

My name's Mike. I have a two-and-a-half-year-old that was diagnosed with autism, and people keep sending you this link that's going around about a three-year-old autistic child that his parents treated them with some CBD oil, or CBD oral gummies, I believe. And he started to talk in two days, you know, magic, wonderful, you know, super drugs, supposedly. Actually, went on PubMed, there seems to be a lot of research between A. and CBD oil, but it's a little hard to wade through. Just wanted your opinions on it.

Yeah. So, yeah, autism's very tough illness for the kid and for the family in a lot of cases. And, you know, there's a whole spectrum of autism. Some kids are very high functioning, some not. And people are desperate for an answer. That's why the vaccine thing happened because people, really were saying, wow, you know, we could prevent this from happening. There's the side that we want to blame somebody, too.

But really, I think that the honest brokers in that got caught up in it, really were looking for a simple way that we could prevent this from happening to our kids. And if it were just mercury in vaccines, it'd be great. You know, just get rid of it, and that'd be the end of it. We wouldn't have this problem anymore. Of course, it's proved to be infinitely more complex than that. And this kind of evidence is called what? Now, see, this is what we're going to see over the next few months

if Cody actually pays attention to this stuff. So this is, Scott knows, it's the worst kind of evidence. What is it, Scott? Anecdotal evidence, that's exactly right. Give yourself a bill. So anecdotal evidence is just where you say, right, it's where I say, well, this worked for me. You know, I don't even doubt the veracity of these people's claim that they gave their kids CBD oil and within a few days he or she started to get better.

You could explain that a million different ways that they're looking at him differently or the CBD actually, he had some sort of cannabidial defect and that they're replacing. It'd be really interesting. If they didn't give it to him, does he get worse or did he just, was it a cure, you know? Or was he or she going to get better anyway on Tuesday and they just started giving the CBD oil on Sunday, you know, those kinds of things. You just don't know. And that's the problem with anecdotal evidence.

It's not generalizable. You can't say, well, because it worked for me, it's going to work for everybody else. Because CBD oil wasn't just invented yesterday. And I firmly believe that if it was a dramatic or a medication that would dramatically rewire these kids' brains for the better that we would know it already. But let's just say we don't. nobody's ever thought to do it before. Well, that's when we go to the medical literature.

And the medical literature, I did a search, and I searched for cannabidiol and autism, and there were only 14 articles that I could find. And the one that I found is the most recent that was something that we're looking for in quality evidence was this one from frontiers in pharmacology, oral cannabidial, use in children with autism spectrum disorder, to treat related symptoms and comorbidities, okay? So here's the abstract. Children with autism spectrum disorder commonly exhibit comorbid symptoms such as aggression, hyperactivity, and anxiety.

Several studies are being conducted worldwide on cannabidiol use in ASD. We'll just call it ASD from now on autism spectrum disorder. However, these studies are still ongoing, and data on the effects of its use is very limited. So in this study, they're not even looking. to try to, quote unquote, cure autism. They're just using it to treat secondary symptoms. But if it's a cure, they should go, well, hell, we did this and look at these kids now.

All of a sudden, they're high functioning, right? In this study, we aim to report the experience of parents who administer under supervision oral cannabinoids to their children with ASD. So this is not a double-blind placebo-controlled study. So already we can't make generalizable, you know, claims about this. Okay, so Cody, the double-blind placebo-controlled studies where you give one group the medicine, another group, an identical medicine that has no effect that we know of. I actually do know what a double-blown.

Okay, all right. Crazy enough. Well, ain't you something then. That's right. So, okay, so I don't have to explain that. And our listeners certainly know what it is. So it says parents of children with ASD were instructed by a nurse practitioner, how to administer oral drops of cannabidiol oil, information on comorbid symptoms,

and safety was prospectively recorded biweekly. So this is at least a prospective study, not a retrospective study. They do the intervention, and then they follow them forward into the new present. And they were prospectively recorded biweekly during follow-up interviews an independent group of specialists analyze these data for changes in ASD symptoms and drug safety. So here's the results. 53 children at a median age of 11, and they range from 4 to 22, received cannabidial for a median duration of 66 days. So, you know, that's a pretty good amount of time.

Self-injury and rage attacks improved in 67.6% and worsened in 8%. hyperactivity symptoms improved in 68.4% did not change in 28.9% and worsened in 2.6%. Sleep problems improved in 71.4%. Anxiety. Now, how did they, now this is a qualitative assessment of anxiety. In other words, was your kid less anxious? They're not doing a validated screening tool, at least now that I can see. Right. Improved in 47.1%.

So there could be bias, significant amount of bias, because there's no placebo arm in this. You know, particularly if the parents believed that the cannabodial would work, oh, the CBD is like magic. It's really working great. Then they will be biased to give you more positive results. Adverse effects, mostly somnolence, and change in appetite were mild. Conclusion.

Parents reported, reports, suggest. yes, that cannabodial may improve ASD comorbidity symptoms. However, the long-term effects should be evaluated in large-scale studies. So that's where we are. Looks like maybe it'll help for some stuff. It does not appear to be a cure. You'll notice not one of these kids that they report were, you know, cured of their autism or that they, you know, their functional level increased.

Would they have reported that? Yes, I believe they would have. Yes. Okay. If they had some stunning result like that. So I think that it's very interesting. If you're interested in trying this in your child with autism, just please don't do this on your own. Yes, you can buy it over the counter.

Talk to your pediatrician about it. If they're intransigent about it, go find one that's a little more well-read and see if they're willing to work with you on this. And because, and the reason I say that is there was one in ten of these kids. actually got worse, and I don't know how worse they got. So I want you to have support from your pediatrician or your neurologist or whoever you're working with. Well, going back to what you were saying earlier, though, that one in ten, that one may have was going to get worse anyway.

Well, that's right. Yeah, which you just don't know. You just don't know. Because we can't. You can't say that the medicine causes or the good effects or the bad effects because we don't have a placebo arm. But these kinds of studies, because there was two-thirds of the kids seemed to get better. And it was probably different two-thirds got better on two-thirds of different things.

You know what I'm saying? Sure, sure. It wasn't two-thirds of them got better on all of those things. But that's enough to say, you know what, we need to do a double-blind placebo-controlled study. Dig a little deeper. With very well-defined endpoints. Right. And I think breaking down those behavioral endpoints and overall success is a good idea.

Yep. Here's another one that's just from global pediatric health, autism, spectrum disorder, and cannabodial. Have we seen this movie before? And this is somebody saying, let me get there, the free full text. I think this is just an opinion piece saying, you know what, we've been around this block before with hyperbaric oxygen and all this other stuff. And we've been disappointed, so don't get your hopes up. I'm sure that's what they're saying. Yeah, let me read their conclusion.

The use of CBD for clinical applications has gained increasing intention, given its lack of psychoactive properties. In other words, it doesn't make you high. And potential benefits that have been noted in certain disease states, such as pediatric epilepsy, absolutely the drug of choice for certain refractory pediatric seizure disorders is CBD oil. Number one. So when people say to me, well, CBD oil, does it? Work? Well, what do you mean? Work for what? Does it cure cancer? No. Does it, is it an excellent treatment for kids with refractory seizure disorder? Yeah. Yeah. You know, again, do it with under the auspices. You don't know what dose to give your kid. You don't know. You do not know, but your

pediatrician will because there are FDA. No, they will because there are FDA. Okay. Is the FDA got involved with CBD? They, okay. That was my question. Yes, and no. If it's derived from hemp, they're not. Okay, so if it's derived from hemp. Because it's a natural product. CBD is not regulated by the FDA. It's technically a supplement.

They could step in. Yeah, they sell it as a nutritional supplement. If it's derived from cannabis sativa or cannabis indica, then yes. My favorite. Yeah. Then it has to be extracted and the THC has to be removed. and purified, or if it's synthesized in the laboratory, either one of those, then it's got to, then it's a controlled substance by the DEA, and it can only be sold by prescription through an FDA approved process.

Know your product. Okay, yeah. So your pediatrician will know the dose because there is an FDA approved CBD product for refractory seizures. I'm glad to know that the FDA has at least gotten involved a part of it. Yeah, right, right, right. Well, we have medical marijuana in all 50 states. As long as you're willing to use maranol, you know, a drinabinol, it is a synthetic THC. What the hell is a synthetic THC?

It means it's made in the lab not extracted from the plant. They can do that? Yeah, yeah. Sure. Oh, yeah, that's trivial. It really is trivial. That's wild. Synthesizing organic molecules of that size in the lab.

Is that what they did? Okay, this is a, this is a. their Strange Crescent. Is that what they did with fake weed back in the day? Or is that just some underground garage crap? So the synthetic marijuana is what you're talking about, were other cannabinoids. So cannabinoids, this is a large group of cannabis-like molecules, right? Cannabidial is one of them.

Tetrahydro-canabinol is another one. That's THC. I know about tetra. a little bit. Yeah, I'm sure you do being a rock star. Yeah, rock star, that's right. But, you know, and there are other ones, and some of them not only

didn't prevent seizures, but cause seizures and stuff like that, but because they were a different molecule, they weren't regulated by the DEA. That was how they got around that. So if you take, you know, a banned molecule and mess with it, now all of a sudden

it's a different molecule as far as the law is concerned, and you can sell it. You know, on the open market for a while until they catch on and then they bust you again i know they had a problem getting rid of it had they like i don't see i haven't seen it in ages i only i do not advise any of that stuff yeah well good yeah we don't either because um we have a whole spiel about street drugs but um uh i'll i well you'll hear it before too long um let's see so uh yeah they just says there's a policy of literature supporting the clinical evidence for use of CBD and ASD,

CBD and similar products remain a promising yet unproven intervention in the treatment of children with ASD. So that's just where they are. Okay. So if it were a panacea, we'd already know, but it may have some use, but do it under the auspices of your treating pediatrician. If you don't mind, thank you very much. All right. Good question. Let's do another.

Hey, Dr. Steve, I had on squamous cell cancer two years ago. Oh, my goodness. They'd be two sub-lethal doses of cisplatin and additional radiation anyway. Well, hopefully there's some leaves. The thyroid's dead. Colon has no peristolic activity. Yeah. Does the cisplatin continue to have cytotoxic damage in time?

It appears that it's getting worse. As far as the effects. Anyway, if you have any thoughts on that? Okay. Yeah, so Cisplatin is a chemotherapy drug, and it's well known in some people to affect peripheral nerve fibers. When I say peripheral nerve fibers, I'm talking about like in your feet and hands and stuff like that.

It will cause a thing called chemotherapy-induced peripheral neuropathy. Now, he also has the nerves going to his bowel have been affected. And we would treat those things differently, okay? So that'll cause constipation and inability to just have a good bowel movement where you're, you know, actually voiding everything. And so if you will go to my website, because I have peripheral neuropathy myself, and go to my website at Dr.steve.com and then click on for neuropathy sufferers. I've got a whole article on there on nutritional supplements that we use every day in the cancer. Center, and a lot of it came from research, or I want to say research, but information that I found while researching nutritional supplements that might be of some benefit in peripheral

neuropathy, because when I went to my neurologist, they said, well, you got neuropathy, we'll see you later, and I was not satisfied with that, so I just did some, and I'm not a real big, I mean, people I've been listening to this show for ages, know that I'm not real big on nutritional supplements unless there's some reason for it. But I had a funny feeling that there might be a nutritional aspect to this neuropathy. And I was rewarded by several very positive studies, though, none very conclusive either, showing a number of nutritional supplements that can have some benefit in peripheral neuropathy. So I give these to everybody now when they first started.

And we don't have enough people to tell if we're having a huge effect or not. But I know for me it absolutely saved my ass because my neuropathy got so bad that I couldn't stand up straight in the shower and close my eyes when I was washing my hair. But you also identified one of the causes of your neuropathy, too, which helped. And he's kind of identified one of his causes of his neuropathy. Are you talking about the M-T-H-F-R gene, or what are you talking about? No, the statins. Oh, well, maybe. Maybe.

I mean, I still have it, and I've been off statins for ages now. But, yeah, no, you're right. Mine might have been statin-induced, his is chemotherapy-induced, both off of our drugs. Yeah. And, yes, these things can continue to progress for some time. The cisplatin isn't in your system anymore, but the damage is done. Just think about it. Think of, let me give you a good, the best example I can real quick, poison ivy.

So when you encounter poison ivy, it might start on your wrist, and then the next day it's halfway up your arm, and then it's at your elbow, and then it's at your shoulder, okay? And that might happen over four or five days. And you think, oh, it's spreading. I'm scratching it, and it's spreading. That's not what's happening. What happened is you got the insult all at once, but at your wrist, you're. you may have gotten, say, four parts per million, and then in your mid-forearm, you got eight parts per million,

and then your elbow, you got 20, and then your shoulder you got 40, or whatever. It might even be parts per billion, I don't know. But so the place that got the highest concentration is going to be affected first. And that may be the case with this chemo-induced neuropathy, too, where, you know, the insult has felt greatest at the places that are most vulnerable.

And then even though the insult happened, it takes a while for the rest of it to kick in. But the nutritional supplements are things like glutamine. It's just amino acid. What you're wanting to do, alpha lipoic acid is another one that's reasonably well studied. And there are others. Just go to my website.

I've got a whole article there with citations and links to the PubMed article where you can read yourself. And I took a cocktail of those because I was desperate to get some relief and took all, you know, I took all four of them at once. And that really seemed to accelerate the improvement for me. Now, that's anecdotal evidence, isn't it? I'm just saying it worked for me. I'm not saying it'll work for anybody else. But I could not stand up in the shower and close my eyes and wash my hair without falling down. Now I can spin around, dance, beat off, do whatever I want to with my eyes closed and no problem. So, yeah. That's fascinating. So I might have

and better anyway. So that's why we're looking always for more placebo-controlled double-blind studies for this kind of thing. But look at that. If you have any questions, email me at Weird Medicine at Riotcast.com or just click, you know what, forget that. Go to Dr. Steve.com and click contact and just ignore the warnings and email us through there.

Some other things he may try, though, maybe a little manual techniques. Yep. You know, sometimes just manual stimulation from physical therapy tend, you know. it's, you know, acupuncture, etc. So yoga, stuff like that might be able to help him a little bit with his colon moving. Oh, yeah, the colon. Okay, yeah, let's talk about that. Specifically colon, yeah.

Yeah, so the osteopaths have a maneuver for stimulating the colon to move. You could see an osteopath. Yes, you could try acupuncture. It's not going to hurt. Physical therapy. I'd like to see some data on that one, but I'm sure that they're, you know, if the spinal manipulation will actually improve what we call ilias or a paralyzed bowel, then I could see that acupuncture might.

as well. The other thing is there's a new drug on the market called Procalapride, and it's sold under the trade name of Motegrity, and it is an actual bowel stimulant. We haven't had one of these since a drug called Zell Norm was taken off the market about 15 years ago. Maybe it was longer in that. Zellorm was a great drug. It was called Sissopride, but it caused a weird heart rhythm in a very small minority of people, but enough for it to be taken off the market. But this Prucala pride doesn't do that. And you can just take it every day, and it just induces a normal bowel movement. So for people with just a bowel that's just flabby, I would consider this Prucala pride.

So you can ask your primary care about that. And if you just heard this in passing and you didn't get to write it down and your memory sucks like mine does, just email me. And I'll get you the information on that. All right. We got about a minute left I don't know if we got time to do anything We didn't play a song this time We'll play one next time

We need to come up with something Maybe I'll play keyboards on any All right, cool I'll bring a fuzz pedal Oh yeah yeah yeah Okay yeah bring a pedal and we'll figure I might Do you have a little preamp

Actually I think I do If you don't Will a D I work? Yeah Yeah I got all that stuff Okay yeah yeah that'll be fine Okay so we'll do that So we'll see you next week. Thanks. Always go to Dr. Scott and Cody Gilmer. Check out Cody's band Indie Ghost on Spotify or at Indie Ghost Band on Twitter. Can't forget Rob Sprantz, Bob Kelly, Greg Hughes, Anthony Coomia, Jim Norton, Travis Teft, Lewis Johnson, Paul Off Charsky, Eric Nagel, Roland Campo, Sam Roberts, Pat Duffy, Dennis Falcone, Ron Bennington, and Fez Wiley, whose early support of this show has never gone on a.

appreciated. Listen to our SiriusXM show on the Faction Talk channel. SeriousXM. Channel 103, Saturdays at 8 p.m. Eastern, Sunday at 5 p.m. Eastern on demand and other times at Jim McClure's pleasure. Many thanks. Go to our listeners whose voicemail and topic ideas make this job very easy. Go to our website at Dr. Steve.com for schedules and podcasts and other crap. Until next time, check your stupid nuts for lumps, quit smoking, and get off your asses and get some exercise. We'll see you in one week for the next edition. of weird medicine.