Weird Medicine: The Podcast - 398 - Universal Influenza Vaccine
Episode Date: March 18, 2020This is a corona-free podcast (mostly). Questions about flu vaccine, high blood sugar and cardiac arrest, abnormal lab work, and more! Check out withings.com/steve for 25% off the best smart scale on ...the market! PLEASE VISIT: stuff.doctorsteve.com (for all your online shopping needs!) withings.com/steve (for the best fitness wearables on Earth!) Feals.com/fluid (lab grade CBD products!) TRIPP.COM offer code DRSTEVE (relax and get 20% off!) simplyherbals.net (While it lasts!) noom.doctorsteve.com (lose weight, gain you-know-what) tweakedaudio.com offer code “FLUID” (best CS anywhere) premium.doctorsteve.com (all this can be yours!) Learn more about your ad choices. Visit podcastchoices.com/adchoices
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You're listening to Weird Medicine with Dr. Steve on the Riotcast Network, riotcast.com.
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All right, very good.
So here we are.
I'm recording this on Wednesday, March 11th,
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No clue if I actually got to go or not.
no clue if once I got there, I didn't get stuck there because of, you know, SARS-C-O-V-2,
the virus that causes COVID-19, aka coronavirus, which is, it seems like really all we've been
talking about for quite some time on this show, and it's probably going to be for a little while
longer.
So a lot has probably happened, so I'm not even going to try to do SARS-COV-2 news today.
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any news that's completely out of date, be honest with you.
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OK-doke.
Let's just answer some questions.
How about that?
Let's see here.
Well, it would help if I push the right button.
Number one thing.
Don't take advice from some asshole on the radio.
There you go.
Very good.
Thank you.
Thank you, Ronnie B.
No, nothing.
I had a question about blood sugar levels.
Okay.
And my husband unfortunately passed away a month ago.
Oh, I'm sorry.
When I, he had undiagnosed diabetes.
And I'm wanting to know if had I gotten him to the hospital a few hours sooner had we had a better result.
So my question is about blood sugar levels and slipping into a cardiac arrest.
Oh, I'm sorry.
I'm sorry.
So, no, I don't want you blaming yourself in any way.
And there's no blame to be assigned in a situation like this.
The problem with diabetes is it goes undiagnosed often unless you get screened for it.
So getting your physical done every year, getting your blood sugar done, or your hemoglobin A1C, your hemoglobin A1C is a test of,
how much blood sugar is glomming on to the hemoglobin in your blood.
And that gives you an idea of three-month average blood sugar.
So we used to say anything under eight was good,
and now then they ratcheted down to 6.7.
Now it's in the fives is considered normal.
So getting your physical done every year,
get your prostate check if you're over 50,
colonoscopy, get your blood pressure, cholesterol,
and your blood sugar done.
and usually they can catch the stuff,
but undiagnosed diabetes for many people
doesn't cause any symptoms,
and it just makes them feel kind of crummy maybe,
but they just think it's part of normal aging,
and they ignore it.
It's not everybody pees like a racehorse,
even if they do.
Sometimes they don't realize that that's a problem.
They just think they've got a problem with their prostate.
And the problem with having undiagnosed high blood sugar
is that it can lead to coronary artery disease.
So people who have diabetes are higher risk of heart attack, stroke, kidney failure, and that kind of stuff.
So that's what happened.
And it's not your fault.
Unlikely anything you could have done would have changed the outcome, sadly, other than if they could have diagnosed this earlier.
So I'm sorry that happened.
And, yeah, it sucks.
And, you know, knowing that death is a natural part of life doesn't make it any easier to deal with.
And if I can help you in any way, please don't hesitate to call back.
All right.
Well?
About a year ago, I had a checkup with my doctor, and she wanted to send me for more tests
because at that time, she said my A-L-T was high.
my blood screen was 123.
Okay, ALT is a liver function test.
AST was 59, and she said...
Yeah, those used to be called S-G-O-T and S-G-P-T,
and now they're ALT and A-S-T.
It doesn't matter what those stand for,
but those are...
These are enzymes that are primarily created in cells in the liver,
and so when the liver cells die,
they release those enzymes into the bloodstream,
and then you can detect them in a blood test.
There was blood in my urine.
Of course, I didn't bother to go.
And a year later, my numbers are back to normal.
42 for ALT and 17 for AST.
Good.
However, my doctor, my gastroenterologist, he wanted me to see my primary because my
creatinine level is high, 1.40.
Okay, so creatinine level is a function of kidney function.
So you and I, if we have normal kidney function, we very efficiently filter out creatin.
Okay, so there will be way more creatin in your urine than will be in your bloodstream.
And when your kidneys stop filtering efficiently, that creatinine level,
starts to rise because we're no longer able to filter it out as efficiently. I hope that makes
sense. So that is something that's a marker that we look at for kidney failure. Now, 1.4,
no, that's not kidney failure. We might call that renal insufficiency. But you can see that
from, you know, every once in a while if someone's dehydrated or something like that.
you'll see a transient rise in creatin.
So the question is, is it chronically elevated or was it just one time?
Let's see what he says, if he does say anything.
I have records going back to 2014.
It's usually in the point nine's.
Now it's up to one and a half.
Went back to my primary.
She wants me to go again, of course.
she references me to refers me to a hematologist oncologist at my kidneys even though there's no blood in my urine anymore
but she says my other counts are behind especially my red blood counts my hemoglobin was 18.4 my my hematocrat was 57.7 I don't know what any of this means of course one thing that is
using my new trough neutral fills absolute from 2014 to 2016 was 4,500 to 5,200.
Now they're measuring it says 5.7. I don't know if they're...
That's 5.7,000.
Measuring in a different way.
Yeah, they are.
Something really strange happened with that.
Any information you can give me would be of clearly help.
I appreciate it.
I listen to your podcast every week.
Okay, good, good, good.
So you'll hear this.
So, yeah, the 5.7, that's going to be 5.7,000.
So that's still in the same range.
So I want to hear that hemoglobin and hematocrat again.
Let me run out.
Especially my red blood counts.
My hemoglobin was 18.4.
My hematocrat was 57.7.
Yeah, okay.
So hematocrat is if you, that's basically,
the percentage of blood volume that is red blood cells.
That's kind of a way to think of it.
So if you spin down blood into a very narrow tube and you put in a centrifuge and the red blood cells
go to the bottom, then you can measure the top from the very bottom to the top of the
clear fluid because there will be down at the bottom there will be debris and red blood cells
at the top will be clear fluid.
You measure the whole distance, that would be your 100%.
And then let's say that the red blood cells go up half the way,
then that would be 50%.
That would be a hematocrit of 50, okay?
And then the hemoglobin is another measure of red blood cells.
And both of these are elevated in him.
Not crazy elevated, but they're elevated.
So, and he's had this issue with these transient liver enzymes, plus he's got a little bit of renal insufficiency.
So I don't, at first when he said that they were sending him to a hematologist, I couldn't figure out why.
But now I understand why.
They're looking to work him up for a what's called a polycythemia or an overabundance of red blood cells.
This can be caused by smoking.
He didn't say whether he smoked.
or not. Carbon monoxide exposure, but it can also come from the bone mirror itself. So a
hematologist would be the right person to work that out. And give us a call and let us know what they
say, because I don't want to make any, you know, any bench or sidecar diagnoses at this point.
But I can tell you that's why they're sending you to that place and what they're going to be
looking for.
And that creatinine is not crazy high.
But when you have an unexpected abnormal lab test, the first thing you do is repeat it.
It may do a thing called regression to the mean.
In other words, the next time they do it might be 1.2, and then 1.1, it's working its way back
down to normal.
On the other hand, it may be 2, and then 2.5 and 3, and now you know you've got a problem.
But one slightly elevated creatinin doth not renal failure make.
But that combined with the transient liver enzymes and the elevated red blood cells that would warrant further investigations, really all that is.
Could be something completely benign.
Okinault.
All right.
Let's see.
Let's do this one.
We're some professional advice, except for FugP.A. John, I guess I'd rely on Dr. Steve here.
Anyway...
That's right.
Okay.
By the way, ladies and gentlemen, this is a phone call by Stacey Deloche, lest I not recognize him when he calls him.
Listeners from three weeks ago will know what I'm talking about.
All right.
Take it away, Stacey.
Got two bone spurs, one on the bottom of my heel, one coming out of the back, pointing up in my heel, according to the x-ray.
Is there any way of curing that without surgery, either through physical therapy or diet or any other way of doing that?
Yeah, it's a great question.
So he has bone spurs, and most people think the spur is what causes the problem, because the spur is actually, you know, it's a pointy piece of bone.
and surely to goodness that's what's causing the pain
and actually the spur itself is more likely to be a symptom
of the tension that's being placed on that bone
by the ligaments and tendons around it rather than the cause
so when you have it on the bottom of your foot and it's going forward
that's usually caused by a thing called plantar fasciitis
so you have this sort of inverse suspension bridge under your foot
and every time you step on it you expand it
and that it just constantly is pulling on that heel bone
and you can get pain there
and it's actually pain in the ligamentous structure
that's supporting the foot in sort of the arch of the foot
and there are lots of things that you can do for plantar fasciitis
the one that they really don't do much of at all is surgery for it,
even though when you do an x-ray, you may see one of those bone spurs.
And that's just because bone will grow in the direction of stress.
And that's a really smart design.
You know, if you walk in a certain way and you put stress on your hip,
and say that it's abnormal, that hip will actually remodel
in the lines inside the supporting stress,
scaffolding will realign itself very slowly, albeit, but they'll do it to reflect where they're
feeling the stress. So we think a bone as being like rock, but it's not. It's living tissue. It's
just moving really slowly if it moves at all. So when you just keep tugging on it, you can actually
extrude out bone cells that will then form bone and make a spur. So wearing a tully heel cup,
doing foot stretches.
You can go to places like fleet feet if you have one of those in your area and they have a sock
that has Velcro on the front and a strap that you can strap to the front of your shin
to stretch out your foot for plantar fasciitis or heel spurs, runners heel, all that kind of stuff.
And then the one that's in the back that's pointing up is just from his Achilles tendon doing the same thing.
It's doing exactly the same thing as pulling.
So he may need to see a podiatrist to get some inserts in his shoe to take off some of the pressure from that calcaneus bone, which is the heel bone, take some of the pressure off of it from all the ligaments and tendons that are you pulling on it.
So, all right.
Let's see here.
Yeah.
Uh-oh.
I've been doing Brazilian Jiu-Jitsu and MMA off and on for about 20 years
and when I rotate my head I show a crackle in my neck
now I don't feel any pain but what is that it's kind of weird
also Dr. Steve you should go on the Matt Sarah
and, well, Jimmy Norton, a UFC podcast.
Really?
That'd probably be a good show.
And can you revive the Chippa?
No.
I can't.
Why would I revive the Chippa?
No, I don't have a whole lot to say on you.
I was on Hammer Fisting podcast with Lewis Gomez a couple of times.
Then he quit asking me on.
I think I was just boring and stupid and didn't know enough about sports.
medicine to really say anything and that was of any interest whatsoever but I love
MMA I love to watch it just don't know anything about it so neck cracking is very
common I can crack my neck right now I don't think you can hear it let me see if you can
hear it I doubt you can hear that but I can hear it as very loud in my head
that's just caused by the tissues of the neck rubbing against each other.
You know, what I want you to do, if you ever have a chance is to look at a model of this human spine,
it's an incredible feat of engineering.
You know, these little pedicles and these other little outcroppings, you know, lay on top of them,
and each one lays on top of the other one.
And they're not placed there like blocks.
They grow like that.
It's really neat.
And it's very clever.
and it's pretty flexible within limits.
But these tissues kind of start grinding against each other,
and it doesn't necessarily mean that anything really bad is going on.
You may have a little bit of degenerative joint disease,
but it doesn't cause pain.
It really is probably not a problem.
So now people will endure trauma and get osteoarthritis from it years later.
I've seen lots of people with bad knees, men particularly, and I'll say, did you play football?
And I would say about 88% of them were football players.
It seems like 10, 15 years later, now they've got arthritis in their knees.
So you will see that from time to time.
But, yeah, I wouldn't worry too much about that.
Now, if you have any associated symptoms when it cracks, numbness in your fingers, numbness
running down your arm, electricity is shooting down your arm, then you've got to get checked
because that's a sign of a pinched nerve.
All right.
Hello, we are medicine.
Hey.
This is, um, from New York.
I just got a couple of goofy questions.
I was just watching a YouTube video.
You know, guys take their batharm.
It's in liquid and oxygen.
It doesn't dissolve, but it sprees instantly, you know.
He then takes the frozen bathbion and the water in the bathtub boil.
It literally boils in like empties by half.
How does that happen?
I'm having trouble understanding him.
If you put something like liquid nitrogen or carbon dioxide, it's a better one.
Solid carbon dioxide would call dry ice.
If you put it in water, yeah, it will look like it's boiling.
What it's doing really is just outgassing.
So it's not boiling in the sense that the water is changing from one phase to another.
That's what really boiling is, is where water changes from a liquid phase to a gaseous phase.
What really is going on is, and so it's outgassing, and so you get this bubbling up.
You throw dry ice in water, it outgasses, but the water itself doesn't change from water to gas.
Most likely it's changing from water to solid, which we call ice.
as it tries to, as it, you know, encases the dry eyes.
So anyway, sorry, I couldn't answer the rest of it.
I know he was asking about the lethal dose of nicotine.
And the LD50 of, in other words, the amount of nicotine that will kill 50% of humans is considered to be 0.5 milligrams per kilogram.
So that would be like 35 milligrams.
Now, I'm not sure how much is in a cigarette.
So let's find out.
Well, let's see if Echo knows.
Echo, how much nicotine is in a single cigarette?
According to an Amazon customer,
the average cigarette contains around 12 milligrams of nicotine.
However, the MG of nicotine in cigarettes can range from 8 milligrams
all the way up to more than 24 milligrams,
depending on the strength.
Okay.
It's from some Amazon user.
I don't know if it's true.
So 0.5 to 1 milligram per kilogram can be a lethal dosage for an adult human.
Now, remember, just because the cigarette has that much doesn't mean you're getting that dose.
That would be the more accurate question.
What dose of nicotine do you get when you take a puff on a smoke?
Well, let's look that up.
Echo, how much nicotine do you get in every puff of a cigarette?
A response from an Amazon customer about CD cigarette says about 10 milligrams in each cigarette.
Hmm. Okay, I don't know. I should have looked that up before I started doing this podcast. But anyway, so it unlikely to have a lethal dose, in other words, from a single cigarette.
And, but I'm going to look that, well, here's nicotine poisoning.
Let's just look and see what our old buddy Wikipedia, which I know is not a great medical source,
but is not bad, actually, for things like this, because there are a lot of people out there that fact-checked this stuff.
So the widely used human LD-50 estimate of one milligram per kilogram was questioned in a 2013
review in light of several documented cases of humans surviving much higher doses.
The 2013 review suggests that the lower limit causing fatal outcomes is a thousand milligrams
of ingested nicotine corresponding to 13 milligrams per kilogram orally.
So you'd have to eat it, just smoking it.
Because when you smoke it, the nicotine comes in to your body and then you metabolize it very
quickly. An accidental ingestion of only six milligrams may be lethal to children, so don't let
children accidentally eat your nicotine gum, keep that stuff out of their hands, and cigarettes.
Well, can we just not have cigarettes in the house if there are kids? You know, if you're an adult,
do whatever you want to do, but I don't understand it. But anyway, yeah, there you go.
Okay, here we go.
It says the recent rise in the use of electronic cigarettes,
many forms of which are designed to be refilled with nicotine-containing e-liquid supplied in small plastic bottles,
has renewed interest in nicotine overdoses, especially in the possibility of young children invests ingesting the liquids.
In 2015, Public Health England report noted an unconfirmed newspaper report of a fatal poisoning of a two-year-old child.
Two published case reports of children of similar age had recovered after ingesting e-lector.
liquid and vomiting. Yeah. So if you have a bottle full of e-liquid, look and see how many milligrams
of nicotine are in there, and you may be in possession of a fatal dose of that stuff. So
that's pretty spooky. So be careful out there.
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All right, back to the show.
Let's take another couple of questions, then we'll get out of here.
Hey, Dr. Steve.
It's Ryan out in Chicago.
I got a question for you.
You keep talking about the universal flu vaccine.
That's correct.
It sounds awesome.
I was watching this docu-series on Nesson.
place called pandemic and they had touched on where they are the development with
universal food vaccine and they said they already have something but it entails
getting instead of just one shot a series of seven shots and just for
arguments sake let's say I'm not a millennial snowflake well I know what that is
might I go about getting these seven shots and and what would it entail I mean
If I could not have to go every year and get the flu vaccine, I'm willing to get seven shots.
I'm willing to get seven shots in quick succession if necessary.
So just wanted to hear your thoughts on it.
Thanks so much.
Bye.
Yeah.
So what he's talking about is a universal influenza vaccine, which is something we desperately need.
Right now we're guessing which of the viral proteins on the surface of the influenza virus will be present.
when flu hits our communities.
And, but the stupid thing mutates.
So every year it's something different.
And sometimes the flu vaccine is 6% effective.
And other times it's 40% effective.
What we need is a universal flu vaccine.
So you get one flu vaccine, just like you got one series of measle vaccines.
And I haven't heard this seven.
shot thing, but you have to get more than one
MMR, and you have to get
more than one
Schingrich's vaccine. I had to get two
of those. So I doubt it'll be
seven when they finally finish it.
It might be two or three, though.
But then when you do that,
that'll be the end of influenza.
Just as
we basically eradicated
measles in this country until people
stopped vaccinating their kids.
and now measles is making a comeback, but back, you know, 10, 15 years ago,
there was not a single native case of community-acquired measles in this country.
They were all people, the people that got measles that year all got it from or brought it here from other places.
So now we're seeing it come back again.
Hopefully people will get some sense and start vaccinating their kids again.
But anyway, we need a universal influenza vaccine.
mainly because we don't want the influenza pandemic of 1918 to ever happen again.
Now, it's unlikely to happen.
Dr. Scott and I talked about this last show that an influenza pandemic that kills 1% of the world's population unless it's completely resistant or really fastly or rapidly fatal is unlikely to happen because now we have.
ventilators and we have Tamiflu and zoofluza and relenza and we'll have other medications and hopefully
a universal vaccine and we have vaccines in general right now. So, you know, I'm hoping for the future
that we can have a flu influenza free future because this stupid virus, enough's enough with this
effing virus. 30,000 people in this country dead this year. So far from influenza enough. So your
days are numbered influenza we're coming for you all right piece of crap virus
hey dr steve my name trying uh i've recently quit smoking congratulations it's been 30 plus days
excellent i've been using the nicotrol okay uh went to a breakup right before i started oh here
Here we go.
Quit smoking program and we were working stuff out and emotions went crazy two different times
right in a row.
Yep.
Once where I quit smoking completely and then the next time when I quit the neck control.
Is that normal to have just emotional just blow up?
Yes.
I don't know where.
Thanks boss.
I appreciate you help pushing me to quit smoking.
Oh, thank you for quitting.
And yes, part of the withdrawal from nicotine is a little bit of emotional lability.
And the other thing is that the brain also will mite at that time and say, you know, dude, you'd feel better if you just smoke to cigarette.
Don't fall for that.
That's the lizard part of your brain trying to get you to smoke again.
so don't do it
resist
go beat off
go eat something
drink something
just don't smoke
because you're vulnerable
right now
I used to go
six weeks
and then my wife
would piss me off
and I'd go well
by God I'll show her
I'm going to smoke
and I'd go smoke
well I didn't show her anything
I was just showing
myself what a dumbass I was
so eventually it's stuck
and mostly I did it
just to show her, you know, because she still smokes out of hell with her. But I, you're going to be
vulnerable at six weeks and six months at six months. You're going to say, oh, I got this thing
licked. I could just have one. You can't. You can't have one. If it breaks your heart to not
smoke, that you can say, look, if I ever have a terminal illness in the future, then I'll start
smoking again. And that's totally fine to do that because that's what I did. That helped
me say it's not goodbye. It's so long. When I get a terminal illness, I'll pick you back up again
because at that point, who cares? But the weird thing is, at this point, I've been quit 25 years,
I guess at this point. I have no interest. If I get a terminal illness now, there's a lot of stuff
I'll do. And visiting the bunny ranch is one of them. But smoking is not one of
of them. I won't be doing that. So there you go. And visiting the Bunny Ranch is a euphemism for
you figure it out. Anyway, all right. Listen, thanks always go to Dr. Scott. When he's here, we can't
forget Rob Spence, Bob Kelly, Greg Hughes, Anthony Coomia, Jim Norton, Travis Teft, Lewis Johnson,
Paul Ophcharsky, Eric Nagel, Roland Campo, Sam Roberts, Pat Duffy, Dennis Falcone, Ron Bennington
and Fizz Watley, and Chris Stanley, who's early
support of this show has never gone on appreciated. Listen to our SiriusXM show on the Faction Talk
channel, SiriusXM 103, Saturdays at 8 p.m. Eastern, Sunday at 5 p.m. Eastern on demand and other times
at Jim McClure's pleasure. Many thanks to our listeners whose voicemail and topic ideas make this
job very easy. Go to our website at Dr. Steve.com for schedules and podcasts and other crap.
Until next time, check your stupid nuts for lumps, quit smoking, get off your asses, get some exercise.
We'll see you in one week for the next edition of Weird Medicine, and next week we'll be live and
be talking about coronavirus again.
I'm sure we'll see you then.