Weird Medicine: The Podcast - 507 - Monkey See, Monkey Doo Doo

Episode Date: May 27, 2022

Dr Steve, Dr Scott, and Tacie discuss: Do we need to worry about Monkey Pox? Viral Oncolytic Therapy Vaginal rejuvenation Glutathione Mariko Aioki effect part deux? Excitatory histamine release playing video games Can humans train to withstand high g-force? Viagra dependency: Myth or fact? Please visit: stuff.doctorsteve.com (for all your online shopping needs!) simplyherbals.net (now with CBD nasal spray!) thelaughbutton.merchtable.com/weird-medicine (stupid merchandise!) Also don't forget: Cameo.com/weirdmedicine (Book your old pal right now while he’s still cheap! "FLUID!") noom.doctorsteve.com (the link still works! Lose weight now before swimsuit season!) chef.doctorsteve.com (Green Grocer is the best meal kit we've tried! Get free stuff!) CHECK US OUT ON PATREON!  ALL NEW CONTENT! Robert Kelly, Mark Normand, mystery guests! Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices

Hey, it's Joe DeRosa here, and you're listening to Weird Medicine. If you ever get lost in a corn maze, just follow your ears. Why aren't Windows good liars? Because you can see right through them. Sometimes people ask me if I speak lizard. I don't, but iguana learn someday. If you just read the bio for Dr. Steve, host of Weird Medicine on Sirius XM 103,

and made popular by two really comedy shows, Opie and Anthony and Ron and Fez, you would have thought that this guy was a bit of, you know, a clown. Why can't you give me the respect that I'm entitled to? I've got diphtheria crushing my esophagus. I've got Tobolivir stripping from my nose. I've got the leprosy of the heartbound, exacerbating my infectable woes. I want to take my brain out and blasted with the wave, an ultrasonic, ecographic, and a pulsating shave. I want to magic pills

all my ailments The health equivalent The citizen cane And if I don't get it now In the tablet I think I'm doing Then I'll have to go insane I want to requiem

For my disease So I'm paging Dr. Steve Dr. Steve Yo-de-ho Take a careful I do the learn of fame Yo-de-Yo-i-o

I need some touching Yo-ho-ho-ho-de-o From the world famous Cardiff Electric Network Studios It's weird medicine, the first and still only uncensored medical show in the history of broadcast radio, now a podcast. I'm Dr. Steve with my little pal, Dr. Scott, the traditional Chinese medical practitioner who gives me street crap. The wacko alternative medicine assholes.

Hello, Dr. Scott. Hey, Dr. Steve. And Tacey will be here momentarily. This is a show for people who would never listen to a medical show on the radio or the internet. If you've got a question, you're embarrassed to take your regular medical provider. Or if you can't find an answer anywhere else, give us a call at 3-4-7-7-6. 6443.23. That's 347. Follow us

on Twitter at Weird Medicine or at D.R. Scott, W.M. Visit our website at Dr. Steve.com for podcast, medical news and stuff you come by. Most importantly, we are not your medical providers. Take everything here with a drain of salt. Don't act on anything you hear on this show without talking over with

your doctor, nurse, practitioner, practical nurse, physician, pharmacist, acupuncturous, yoga master, whatever. Good Lord, that list is too long. Tacey gets mad if I read the whole thing. Somebody texted to me

on the voicemail line that the list at the end of the show has gotten so long that it's half the show and it's like nobody listens that long. Who listens to that?

When they hear the music they just click, okay, next one. One would think so, yeah. But there is some ridiculous stuff going on on the shoutouts at the end of the show. please check out stuff.

stuff.doctrsteve.com stuff dot doctor steve.com for all of your online shopping needs and if you will check out Dr. Scott's website at simply herbals.net that would be a good thing and cameo is still a thing and if you want me to do Cletus or Myrtle I'll do that or I'll just say fluids and secretions to your mother

We did that at Mother's Day. A bunch of people wanted me to do cameos where I just said fluid to their mother. You guys are weird, but they're cheap. I just like doing it. I've done like a hundred of them, and I think I've made, I don't know. We worked it out. Beck and I worked out. I told them how much I total I've made and how many I did, and it was like $6 a thing.

So I'm not doing it for the money, if you know what I mean. I'll make it fun if you want me to. And check out Tacey's Patreon, and it is Tacey and me. And we are doing the Patreon of Weird Medicine Special Edition, where Tacey just gives me hell and we answer questions that are exclusive to Patreon listeners. But we also have another show called The Exam Room on there, and that is exclusive to Patreon, where we have celebrities come on, and ask me questions.

That's kind of fun. And we did have Dr. Caldera, aka Joe DeRosa, the owner of Joey Rosa's sandwich shop in Manhattan, and one of my favorite people. And if you want to see how surprising that is, check out the first time we ever encountered each other by going to YouTube and search for Joe DeRosa

versus Dr. Steve or whatever. And I didn't really do anything that funny that day, but what I did do is turn the room against him, and he finally just gave up. And it was quite funny. And I was sitting in the library on the cancer floor when that went down. And if you're ever wondering what, well, I guess I could play some of this, couldn't I? Why not? I mean it's not it's not like it's I'm going to get a copyright strike I could dissect it a little bit before everybody

yeah yeah yeah okay go fuck yourself Dr. Scott let me see Dr. Steve versus Joe DeRosa oh it comes up right there oh okay it's like the first thing okay so what happened was Joe was on the show and he kept saying something I can't remember what it was but he was talking it was some societal concept and he kept saying it over and over again i was just screwing around and i quoted him saying this and then i just cut it off and i went we heard you in all capital letters right and just tweeted it out well apparently anthony saw it or probably sam roberts because he likes to stir up shit saw it and showed it to joe and he was like get him on the

phone. He wanted to give me a good old grilling, right? And so I called in and while I was on hold, I heard this thing that they were doing about Roland Campos and it was this bit

that one of the interns did called Don't Get the Panda Angry and it was going Don't get the Panda angry! Because if you don't know that, you won't understand what I said at the beginning. But I heard that while I was on hold. And I was trying to think of things that I could say because I knew he was getting ready to shit on me, right?

So I'll just play a little bit of this. He's on the phone. Oh. Dr. Steve. Hey, you know what? Excuse me, Dr. Steve. Well, you can hear Joe laughing, like, oh, boy, I'm really going to get this guy. Hi.

Hello. Well, there seems to be a little bit of a problem between you and Joe DeRos. And girl laughed de Rosa. Okay, so the first thing I said was old girl laugh, De Rosa, because he has a high-pitched laugh. And I wanted to make the first blow, if I could, because I knew after that I was going to get cut to ribbons. Oh, shit. Well, there seems to be a little bit of a problem between you. You can hear me going, oh, geez.

And Joe DeRosa. And girl laughed at Rosa. Oh, shit. You know what, Steve, listen. First of all, I want you to shut your dumb prescription right in face. Rosa angry. Oh, shit. Big boy's got a podcast now.

He thinks he's one of us. Okay. At that time, I had a show on Sirius XM, but I didn't have enough wherewithal to point that out to him. Also, one of the jokes that I had that I didn't use was Joe was on a show, I think, I was going to ask him, hey, what was that HBO show you were on, Joe? I remember seeing you on that. It was called Bored Tears, and I was going to say. And I didn't want to sound like stuttering John, telling the jokes I was going to say,

but I thought this one was pretty good. And I was going to say, oh, no, I didn't mean your audience. I meant, you know, the show you were on. And, you know, anyway, so it sounded better in my head. Anyway, so, yeah, check that out if you want to. Now that the rest of it is pretty self-explanatory about that beginning. part is difficult to understand please check out dr scott's website at simply herbals.net simply herbals dot net anything going on over there dr scott just same the same old just the

mostly nasal sprays yeah lots of nasal sprays well tis the season oh my gosh it's been awful this has been a bad one you know i was saying it's this has been the most beautiful spring i've ever seen here yeah um but the side part of that is it you know with a beautiful spring i guess comes extra pollen. Yeah. Who knew? Yeah, yeah, yeah. Oh, my God, it's awful.

Yeah. I have never seen this bad. Well, and I think also we had a really warm winter. Yeah. And that doesn't kill a bunch of stuff. And so more stuff is still alive. Plus, if it was damp, which it was. Which it was, yeah.

Then you've got more mold and just shit floating around. Yeah, you know what it looks like, too. It just seems like we had such a wonder. beautiful, you know, wet spring and everything's growing so robustly. It is. It continues to grow and create more pollen, which I think we lost a lot of last year. Remember, we had that late frost, and it almost killed some of my trees. And this year, they've doubled inside of this.

It's just crazy. He says that as Rosie sniffs his crotch. Oh, yeah. She's well trained. Rosie and Ralphie are here. I don't know if we'll get them on camera. She's a good baby. I don't know if you can see Ralphie.

What's he doing? Ralphie's not such a good baby. Watching Tacey drink. Rosie's a good baby. I remember a long time ago we had Ozzie, when we had Ozzy, and he would lay in the corner. And he was such a big dog. His respirations were so loud. And I remember we would ask him his opinion, and I would just turn his mic on and he'd.

Yeah. He was a good one, wasn't it? He was a good. Oh, gosh. All right. Very good. All right. you got some stories for us yeah you know we keep hearing about this monkey pox okay so i thought

we talked about that for just you need to talk about monkey pox yeah because it's something we haven't really cared here comes another you know pandemic it's not and it's not number one it's not but anyway go ahead well and i and i think that's that's what a lot of people have been asking me and and they've been asking you too and the bottom line is is the monkey pox have been around for a long time yep you know similar to the coronavirus um It's probably been around for a long time. It was first discovered in 1970 in humans. Yeah, yeah.

That was the first time it was, but yeah. Yeah, I'm sorry, but they just hypothesized been around for years. And they say it's in the same family as the smallpox. Yep. But they were just talking about a couple things to remember. This is not COVID. It is not spread like COVID. It's with the monkey pox.

It has to be almost skin-to-skin contact and over a long period of time. It's not like smallpox, which was very contagious. And it's not like chicken. Which is also very contagious. Or not like COVID, which, you know, you can be in the same room with it. But, yeah, it has to be typically up close, skin contact for a longer period of time. Yep, yep. Yeah, because it's not, it doesn't like living in humans.

It will live in humans. So probably with monkeys, they're spreading it all over the place. It might be, I don't know what. Streatner stuff. I don't know what the contagion number for monkeypox is in monkeys, but it's very low for humans. And, yeah, it was first identified in Zaire, and then when a nine-year-old boy developed a smallpox-like illness, and they had thought at that point that smallpox was nearly eradicated,

but so they were still running around trying to catch smallpox cases. And this one was different, and it was confirmed as human monkey pox. And then they had similar cases in 1970. and 71 in Liberia, Nigeria, and Sierra Leone. And it was first identified, it was limited to the rainforests of Central and Western Africa. And then 2003, we saw cases in Western Hemisphere. Of course, we're a global economy, and people are moving around, a lot more mobile now than they used to be.

And in 2003, there were a lot of people identified in the Midwestern United States who developed fever rash and these respiratory symptoms and lymph adenopathy, which means enlarged lymph nodes. And they were exposed to pet prairie dogs, and the prairie dogs were infected with monkey pox. Oh, my goodness. Isn't that crazy? Yeah. So we could call it prairie dog pox. But, yeah, most of the confirmed cases were from direct contact or exposure to ill prairie dogs.

And they, the prairie dogs were, had profuse nasal discharge and ocular discharge. So they had stuff coming out of their nose and their eyes and they were breathing fast. So if you ever see a prairie dog that's snodding and looks like it's crying and it's breathing, stay away from it. You're probably too close anyway. Don't help it. Right. If you can see that, you're too fricking close anyway. It's true.

Very well said. Oh, my gosh. So other rodents can carry it as well. But then humans can just get it and, you know, pass it from person to person, but that's harder to do. And it looks like a regular pox-type virus. You know, it makes postules, and then they burst, and, you know, they ulcerate and stuff like that. So the current outbreak is evolving. There was one case of monkeypox in each of the following U.S. states as of May 25th, which is today when we're recording that,

That's California, Florida, Massachusetts, New York State, Utah, and Washington State. And so we'll just have to keep an eye on that. But mortality rates range from 1 to 10 percent in Africa, but there have been no fatalities in the United States in the 2003 outbreak. So we don't expect any. We've gotten a little bit better at treating stuff like this, so we'll just see. If you had the smallpox vaccine, you're good. it's felt to cross to be cross-reactive

if you get monkey pox it'll be milder and you may be protected from getting it well that's pretty cool so are you supposed to do most people have the smallpox well they stopped doing it

after they eradicated it let me see when was that's a great question taste of course it is taste of you and I might be in trouble he's probably okay discontinued let me see

back in a good old days when Dr. Steve was young yeah um okay it was successfully okay smallpox vaccine was stopped in 1972 after the disease was eradicated in the united states so if i missed it yeah tacy would have missed it so anybody born before 1972 probably got smallpox vaccine you know i'm already seeing on facebook i'm going to refuse that jab too i'm already seeing and i've seen that not just once or twice, but about 20 times. Yeah, this isn't smallpox.

I don't think they're going to ask for vaccination for this one. Well, I know people who aren't going to take it anyway. Well, okay, fine then. But if smallpox was still a thing, they would all be lining up to get it. If people

had seen what I saw, I mean, and my grandmother saw when you would have 10 kids, because you'd hope that three of them would survive because these fucking viruses and bacteria and stuff. Tetanus, rabies. I mean, come on. Now, I wonder how many people

who don't want to get these jabs maybe just they don't want to get it because it's new, and I get that. Believe it or not, I do understand people's reticence on that, but are they cool if they got bit by a rabid bat would they get vaccinated for that? So they're not against all vaccines, they're just

against new vaccines. Well, were people back in the day that were against influenza vaccines, against all of the vaccines that have really made our lives better, and there were people at that time that were against those as well. Still people today, a subset of people don't want to get the measles vaccine, even though measles kills one kid out of a thousand that it infects and killed one of my friends in kindergarten because we didn't have measles vaccine back then. So, you know, anyway.

All right. Yeah, I don't blame them. Right now, I wouldn't recommend people run out and get a smallpox vaccine for monkeypox. It's just, you know, know your partner if you're going to be having close intimate contact with somebody. All right. Good one, Scott. Oh, yeah. What else you got?

Well, interestingly, especially right. I'm glad, you know what? I'm glad you brought that up because I didn't even think about talking about monkeypox today. And it's like, no, people are talking about. this. I'm an idiot when it comes to come out with topics for the show that are topical. Yeah, certainly current, very current, which is cool.

Thank you for bringing that up. But, you know, this is right down your, right down your lane there, Dr. D. D. Farsht human patient is injected with revolutionary cancer-killing virus after a successful test on animals show it can shrink colon, lung, breast, ovarian,

and pancreatic tumor. Wow. So this is a viral oncoletic therapy. Tell me more about it. It's an oncolitic virus. It's called Vaccinia. Vaccinia. It's been specifically genetically in the area. Vaccinia has been around for a long time.

Vaccinia. But I mean, it's a known virus, so they must have engineered it. Okay, okay. Yeah, I guess that's what it is. But what they've seen is that it can help prime the patient's immune system to not only attack certain types of cancers, but also to increase immune response. So they're genetically engineering it to fight certain cancers. Interesting. Immugene Limited, I guess, is the company that's a, they specialize in novel treatments for immunotherapies.

Well, Vaccinia is a well-known, well-studied virus that belongs to the Pox virus family, so it's topical in that regard. Okay. And it's got a big, giant, linear, double-stranded DNA in it. So it's kind of easy to mess around with its genetic makeup. Okay. So I'd like to know more about this because, number one, you don't want this virus getting out of the patient. So they have to decrease it genetically modify it to decrease its virulence because we don't want I Am legend to happen. No.

Because that was a cancer vaccine. If you remember, Emma Thompson, it was a great sort of red herring. But you've got Emma Thompson in this movie at the beginning. You're like, oh, this is, she's going to be in the movie the whole time. She was literally in it for a minute talking about how she, spoiler everybody, a movie came out 20 years ago, how she had developed a vaccine for cancer. And the next thing you know, it's the, you know, the next scene is just zombies running around wild. And one guy was not affected.

But it was a pretty good movie. The book was better. I'm going to tell you that. But the movie had kind of a hopeful ending, whereas in the book, spoiler, the book came out 50 years ago. He met with the vampires. They were more sort of vampires in the book. And he met with them, and they said they were terrified of him. That was the thing.

They were coming after him because they were scared of it because he was different than they were, which was pretty interesting. you know he could walk in the sun and they couldn't and all that stuff but anyway yeah check that out it's a good book uh so yeah the vaccinia virus so oncologic therapy is a big deal eventually we will be taking people's own cells out and training them to do this but right now what they're using these viruses for is to attack certain cells and then signaling that these cells need to be destroyed and then the the immune system comes and does it so on our website at dr steve.com if you click on the link that says pseudoscience non-sudoscience cancer cures there's a story that I had about multiple myeloma being treated with measles vaccine so measles vaccine is a live

attenuated virus and they genetically engineered it to accept a radioactive iodine, not for therapeutic purposes, but for tagging purposes. So they gave this person six million doses of measles vaccine, and they got kind of ill, but when they got over it, they injected this person, if I remember this correctly, with a low dose of radioactive iodine, and then those measles viruses should have made receptors on the surface of the cells to pick up that radioactive iodine. And when they scan these people, the measles vaccine lit up the multiple myeloma. Multiple myeloma for people who don't know is a cancer of the bone.

And it's called multiple because it's everywhere. And it infects lots of bones and causes painful tumors and stuff like that. So it lit these cancerous tumors in the bones up when they scan them. And then within about a month, all the cancer was gone. Now, this is a very limited trial. They just did this as a proof of concept kind of thing, but it was amazing. So I knew back then that was, that probably came out 10, 15 years ago, that they would start to commercialize this. And I'm quite sure that this study was funded by someone that wants to make a billion dollars off of this.

And if it works, God bless them. because I've always said these kinds of treatments probably wouldn't help me, but they would help my kids and my grandchildren. This kind of stuff, if they're this close to doing a clinical trial, if it's a phase one trial and it works, we'll be in phase three trials in no time, and then it'll hit the market in a year or two. So it might help us after all. Yeah, I believe they're in phase one clinical trials.

Yeah, so this was a phase one clinical trial. So remember everybody that phase one clinical trials are. proof of concept you give it to maybe 40 people just to make sure you're not killing them and then you could do a little bit of efficacy and see if it works kind of stuff but there's

not large enough numbers to see rare side effects or to make any big claims about how effective it is. Then you do a phase two with maybe 300 people to look for safety and then you do a phase

three with 30 you know, 3,000 to 30,000 people to look for rare adverse effects and to lock in the effectiveness of this treatment compared to a placebo. And then if you can show statistically significant benefit and it's safe, then the FDA will let you put it on the market. And then you do phase four study, which is post-marketing, when you've got millions of people. And that's when you'll pick up really, really rare adverse effects. You know, the one and a million kind of stuff. So that's very exciting.

Pretty cool stuff. Yep. Cancer cells often have impaired viral defenses because they're just shitty cells that shouldn't even be there. And that makes them susceptible to being infected by these viruses. And the viruses can be engineered to give them some advantageous properties. And it could be decreasing their ability to infect healthy cells and granting them the ability. and granting them the ability to deliver therapeutic payloads even to these tumors. So it's not just making the immune system.

You know, if you could engineer a virus to only go to cancer cell, and then you could put a couple atoms of radioactive radium inside there and let it deliver that, that would be cool. So you'd be getting radiotherapy to these cells, and it's only killing the cancer cells. That's a pretty neat thing. It's like a smart bomb. all right that's crazy good yeah it is good all right very exciting well done dr scott

all right and we have any questions in the waiting room none yet okay that's fine uh let's uh let's take a couple phone calls number one thing don't take advice from some asshole on the radio tacy you got any questions for you oh we should talk about before we take questions do you want to talk about what you went through today well i i went through some vaginal rejuvenation I don't really know how to talk about it intelligently because, well, first of all, not intelligent. Yes, you are. Secondly, though, I went through, I underwent two procedures, and one was like a bullet that you put in your vagina and it kind of sends radio frequencies. Okay.

And so I could feel the places in my vaginal wall that were weak. Really? Yes. So, because that's the only place that it hurt. But it's got like metal plates on either side all around it. Yeah. And it feels like it's opening and closing, but it's not. It's just sending out radio frequency.

Right, right, right. It might be causing some spasm of the muscles. Yeah, and then you can increase it on your own time. really you had control over it you have control over it so when you lift your mic up just a little bit i want to hear this there you go yeah it's beautiful you're the only one when when um no this is interesting what you had was a thing called votiva yes and i'll talk about what it is in in i want to hear your experience with so yeah it it doesn't hurt i mean you start off at zero and you increase it by yourself and they put you in a room alone and then you increase it by

two degrees every time do they insert it or did you insert it she inserted it for me um it also had it had some numbing cream on it for the next procedure i underwent okay because i was going to say if they just put numbing cream on and stick it in there it's not going to do anything no no that's like what dr scott and i had are urethrole sounding oh and they put put gel on there just to make themselves feels feel better. It didn't do anything for us whatsoever. It was numbing cream for the next procedure. Okay, good.

I like that. Not for that one because you don't need it for the first procedure. Okay. Since you're in control over it. Now, if you put that at a high radio frequency, if you put that in, you would definitely need numbing cream. But I don't think numbing cream would necessarily help with that. Because I remember the last time I had it done, I coughed and it shot out. And I put it back in.

Okay. Okay. Well, that's true. Yeah, yeah. What else would you do with it? Things are loose down there. Yeah, yeah. So I coughed and it shot out and I put it back in and I didn't know that.

There are people that make a living doing that kind of stuff. And I thought I was going to come up. They use ping pong balls. Well, yeah. I thought I was going to come up off the table. Yeah. Because it hurt so bad because the plates were not in the same place. Oh, okay.

So, see, you can rotate it if you want to. So you should, you mean with the, with the controls? No, just with the bullet. I mean, just with your hand. Oh, okay. I was sort of imagining like a video game controller. Yes. And the second thing was called Morpheus, I believe.

And I don't want to speak out of turn, so I'm not a representative of the company. I'm only a patient. We want to know your experience, and I'll talk a little bit about what the machine is. It has little needles. come in and out. Micronedles, yeah. Yes, and I don't know how deep they go, but you can definitely see them because I saw them push it before it went in, and I was, it freaked me out a little bit, and also radio frequency at the same time. Yeah. So, um, and what's the purpose of all of this? To,

to get better bladder control. Okay. Yeah. To, well, to just rejuvenate the vagina, but better bladder control. I think. think a lot of people do it so that it will look better, although I really don't spend much time looking at it, so I don't care that much what it looks like. No, I don't know who does look at it, even if you're down there doing stuff. I think some people do, and I don't think it's in the 20s range. I think it's the 50 and 60 year old women who are dating younger men. Excellent. Who get concerned about the way that it looks. Okay. And the pictures that I saw when I went to the talk about it were phenomenal. Yeah.

Yeah, I did the training on it. It was pretty outstanding. It's three treatment. Again, this is not an advertisement. Yeah, this is definitely not an advertisement. I'm very interested in your experience, though. I just feel like it didn't hurt. Of course, I had numbing cream in for 30 minutes because I did the first procedure for about half an hour.

Yeah. And then the second one took about as long, but she just rotates it in a clockwise fashion. And. So this one, you've got the person in the room. person is in the room with you. Can we get some music for this, please? I'm sorry. Oh, God.

What's wrong? What's what's wrong with you? Yeah, please I need music. There's a little help from my brother, Debbie. And see, she pushes, she pushes a pedal, and the radio frequency happens, and the needles come out and come back in, and it doesn't feel that way at all. But so it's fast. It's very fast.

And, I mean, there were a few uncomfortable moments, but not in the way that you. you would think. Yeah. But of course, I had numbing cream in for half an hour at least before they did a procedure. Let me ask you something. If you didn't know me and you came in and I did this procedure on you, would you be uncomfortable with, I mean, would you think that I was being inappropriate? Well, considering the type of doctor you are, yes, I would be very uncomfortable. True, true. I went to this hospice doctor. No, I get that. However, there are male physicians who do it.

If you went to a plastic surgeon, I mean, then you would expect that. You would have to give real informed consent on this one to say this is what the procedure is. Because if you just start sticking this thing in and going in and out and in and out with it and going all over the place, because they go all over the place too, right? Well, I have it all over the place on the outside. It was a little tender on the outside. I would say so. Well, I have the informed consent right with me, and I have page 12 that I signed. Okay.

Well, nobody reads those, though, but I'm just saying you would have to tell people, hey, this is what we're going to do. Because if you just started doing it without giving that informed consent to the patient, you would be in trouble really quick, I think. But I, you know, so this thing uses high frequency radio. energy to stimulate blood supply, you know, increased blood supply. We'd call it angiogenesis to those walls. And the purpose from what I understand is to avoid having surgery if you've got stress incontinence. So if you've got a woman that's had a couple of babies and maybe their estrogen levels aren't as high as they used to be, and the bladder wall, which the bottom of the bladder is the top

the vagina is starting to thin, they will often get some laxity in that wall and you can end up getting overflow or you have difficulty emptying your bladder or you may get incontinent when you sneeze or you lift something and those kinds of things. And we talked about that last show or the show before. Yeah, I could feel it when it was up against my, like when I say up against, I mean, near my bladder area. because I felt like I needed to urinate. Interesting.

Okay. Well, I'll be very interested to hear your results with this and see if you notice a difference. It's not like you're... I don't want anybody to get the impression that my wife is just pissing everywhere because that's not the case. But she's texting, so she's not listening to her.

Our son has lost his wallet. Uh-oh. Do we need to go help him? He's freaking out about it. Okay, do you want to go help him? um well uh i mean we can stop i can i can stop recording i let's finish this little segment and then i'll go okay and so just text to him i'm talking about my vagina i'll be right down that's always a i'm just gonna say i'll be right young we need to put one of those apple find it things in his

freaking wallet because this is not the first time so um anyway it was very interesting it wasn't as painful as I thought and I'm very anxious to see the results and no I do not pee on myself all the time. Right, right, right. Thank you. But the majority of women my age, if you ask them if they've had children when they laugh or if they cough, what happens or if they're exercising what happens or or how many times they go to the bathroom at night. I know with our new fancy mattress you don't wake up every time, but it's about six or seven for me. Is that right? Oh, geez. I had no idea. That's way too much. We have this highfalutin mattress, and I mean, it's one of those where if you put a wine glass on it, the person could jump on the other side.

And it was more money than I wanted to spend, but we got a really good deal on it. But it was the best purchase we ever made. It really was. But I had no idea you were getting up that often. I don't know how you get any rest. Well, you get used to it, and then I'd take a nap. Fair enough. She sleeps all day.

But enough about me. and I'm going to go help my son find his son. Yeah, please let me know. And then if you come back, you can tell us. His wallet and I'm just going to take your mic. I'm sorry everyone. Probably in his dirty. You're fine. Blue jeans. Hey, it'll be in his car. Talk like he's

got a question. Is this is it advice for someone with thin vaginal tissues and estrogen cream? I don't know. Wait, what's the question? Was it, is that procedure recommended for someone with thin vaginal

on wall that's what it's for okay that's what i thought but so if you have atrophic vaginitis you got to talk to them because depending on how thin you are people who have prolapses yeah yeah and yeah tacy is saying that uh they are recommending it for people with cysticials which is a really low blooping for want of a better medical term blooping down of the bladder wall into the top wall of the vagina or into the vagina itself so but you need to go to somebody that knows what the hell they're doing and talk to them about the risk benefits and alternatives. That's, again, not an advertisement.

I just thought that was fascinating what she went through. And I've trained on this machine, but she's the first person that I know that's actually done it. How many needles they do they use? Oh, God, the head has a matrix of needles in it. You know, when you would think it kind of plumps up that thin wall and maybe cause a little scarring underneath too, helps rebuild a little bit of the...

Not supposed to scar. I mean, I mean, micro scars. Yeah, yeah, yeah. Just to kind of pump things up. It causes some inflammation and blood, you know, capillary production. And increase in tissue production, and it starts up. Kind of wakes it back up. Yeah, starts up, you know, tissue regeneration.

A healing process, yeah. Yeah, it's pretty interesting. That's cool. Good stuff. All right. Good deal. Let's see. Okay, this person wants to know. Do you know anything about glutathione as a supplement?

I take it. You do? Okay. Let's listen to this. I don't say that. I don't know anything about it. Well, let's listen to this one then and see what he's got. What he's got.

Hang on. Here we go. Hey, Dr. Steve. I had somebody suggest glutisione to me as a supplement. Can you help me understand what it is and what does it do? And would it be a good supplement to incorporate it? Yeah, you know, the thing is, what do you want to accomplish? I always ask people about that.

You know, is vitamin D good furry? And it's like, well, what do you want to treat? Do you want to prevent rickets? Well, vitamin D is freaking great. Do you want to prevent cancer? Maybe not. There's not evidence for that yet. But you take glutathione, so what are you taking it for?

Yeah, I do. Well, they say it's supposed to help with free radicals and inflammation. And I take it because I can't take inseds. for my inflammation, my gout, et cetera, et cetera. But evidently glutathione has made of a couple small amino acids that can help, maybe possibly help fight really, free radicals may be helping fight against inflammatory diseases. My concern about free radicals is this. So free radicals are this, quote unquote, toxin in the body that are very reactive.

and what the concern is that free radicals running around in your body can cause cancer. So the people started taking antioxidants. That's what those are for, is to sort of mop up free radicals. The problem is that our immune system uses free radicals to kill stuff. That's my concern about it. And there were a couple of studies where people were taking antioxidant medications that actually, if they were still smoking, that actually increased the risk of cancer. So I'm always leery when I hear things about mopping up free radicals

because white blood cells actually generate those to kill things. You know, when they envelop other cells or bacteria, well, how are they going to kill them? Well, they generate an area, a gradient of free radicals in some cases, and that's what kills the bacteria. So those could be good. If you wiped all that up, then maybe that would be a bad thing. That's theoretical. Okay. So according to this thing I'm looking at is glutathione helps reduce oxidative stress,

just the way you said, by either stimulating or reducing the body's immunologic response. Well, which one is it? Does it stimulate or reduce it? So, again, I'm a little concerned about that. Autoimmune diseases attack mitochondria in specific cells, and glutathione supposedly works to protect cell mitochondria by eliminating free radicals. And again, that's my concern about it. So if there was a specific reason that you were going to take glutathione, I'd be all in.

I don't know what the data is. And I'm not finding great data either way that it's either bad for you or good for you. I just can't find any studies right now that show me either way. I've got an article here, and it's just, it's a big article, but it's in PubMed about oxidative stress on a brain, especially following head injuries, CTEs, PTSD, et cetera, et cetera. Okay. And I'll dig in it a little deeper before next week. Maybe we can talk about it then.

Okay. If you don't do that, I'm trying to get to the end of it right now. Just see if there's, um. Yeah, there's just not enough scientific evidence that I'm aware of it. And if anybody out there has a good double-blind placebo-controlled study with an end point that we're interested in, I would be happy to look at it. And Scott and I will look at that. Leave us a note, and maybe we'll do that as a story next time. Yeah, because it might be beneficial.

It might not be. Yeah, I just. We'll look it up. You know, I've seen glutathione given IV for things like atherosclerosis and diabetes and things like that. and for side effects of chemotherapy. But those are really specific uses that still are off-label. I mean, as far as I know, they're investigational. We have to be really careful with during patients undergoing chemotherapy,

giving them things to keep, you know, down the oxidative stressors and the, you know, we don't give any herbs that are going to help to stop the process of the gasers. with every working with those free radicals so now um i'm looking at a study in evidence-based complementary and alternative medicine uh-oh there we go dr scott's uh attention i got his attention with that they were using nebulized glutathione but i'm still not seeing good i mean a lot of this stuff is just they're guessing at things so i want to see double blind placebo controlled data I'm sorry.

I'm interested in things that have been used in rats and shown some benefit. But to take those straight to humans just because we think, because it's a related amino acid that it's not going to be a problem, it bothers me. Yeah, Mick, Mick says that it's good for hangovers. Really? Okay. For liver toxins. Well, by God, let's look that up.

We'll have to, we'll have to, we'll have to. We're going to PubMed.gov, and I'm looking up glutathione. I'll have to try just an end of one. I'll give it a shot and see what happens. Okay, fair enough. Okay, here we go. Effects of a preparation of combined glutathione enriched yeast and rice, embryo, soybean extracts on ethanol hangover.

Okay. And this is in Journal of Medicinal Food in 2009, and they said it's suggest. suggested that this reduces blood concentrations of alcohol and acid aldehyde. Remember, acid aldehyde is one of those products of ethanol production or metabolism that causes headache and just nasty side effects. Not only by modulating alcohol metabolizing enzymes, but also by exerting its anti-oxidant activity, there we go again. And it should be a promising candidate for improvements in alcohol hangover.

Of course, that was in 2009. I don't see anything since then, so that's interesting. Okay, so who said that? It's not calling it. It's Mick, Mick K.M. Okay, well, I'm going to give yourself a bell for at least giving us something interesting to talk about. So leave us a note, Scott. We'll talk about this next time.

Gotcha. If there's anything interesting about glutathione. All right. Uh-oh. Uh-oh. Uh-oh. Hey, Dr. Steve. Hey, Dr. Scott, Casey.

Hey. Hello. I was calling about last week's, or maybe it was this week that I just listened to, about pooping in the bookstore. Yes. I would just like to bring up the fact. Okay, so we were talking about this Mariko Ioki effect where people found an association between walking into a bookstore and needing to move their bowels. And I really wanted to go to books a million. and then just ask if they've noticed that people make a beeline to the bathroom.

But I forgot to do that this week. When people go to purchase cocaine, they always have to poop when they get it. What? And that was always tied back to people cutting cocaine with baby lactatives. Oh, I thought it was because they're scared chitless. So, I don't know. When they're buying it. I just thought that was interesting about the bookstore.

Oh, that's interesting. I know that things, lots of things you can cut heroin with, and I wasn't aware that they were doing that with cocaine, but if you're snorting it, I can't imagine that you're getting enough to give you a laxative effect. I do know when I was in Aruba, this friend I was with, this was in the 80s, wanted to, you know, cop man. and so we took a cab to some place and he asked the cab driver there's a place where he could buy something and we went to I was so and so they met these people and he got out of the car

I was so terrified that the cab driver was going to drive away that you pooped yourself but I kept giving it money it was like here here's another five bucks here's another five bucks it was like I was at a strip club or something I just every minute I was giving him more money just to make him stay there because I was scared shitless, but I didn't actually void my bowel, so.

All right. Let's see. Okay. Oh, this is a good question here. Hi, Dr. Stave. Hello. This is Calvin from California. So I have a normal, healthy body, a normal, healthy skin.

I don't have hydritis. Now, I don't have eczema, anything like that. But when I play video games, sometimes when I'm concentrating really heavily, I start getting these itches like methamphetamine. Metamine spiders all over my dermis? Yep. What's up with that? Yeah.

Thank you so much. No, that's a well-known effect. He has excitatory histamine release. So we've talked about people who go out into the sun and they will start sneezing. And other people who will go into the cold and they'll get hives. And some people will get histamine release when they get excited. And when he's playing video games, his adrenaline is pumping. probably someone is calling him naughty things

over the headset and he's getting excited and he's getting histamine release that causes what we would say generalize peritis which is just a fancy term for itching all over and he may be getting hives too and just not noticing it because he's playing video games so that's what that is excitatory histamine release that's right bingo what do you think of that i like it all right good thank you i like it too

What's up, Dr. Steve? This is a stupid question, but I feel like you're the only person I could answer it. Straightforward. When a pilot is in, like, a fighter jet and they're going, like, fucking 30 Gs or whatever it is, I heard that the blood, like, comes down, like, it goes down toward their legs. Like, it comes out of their brain or head or whatever, and that's how they pass out. And I was just wondering if that's something that can be, like, you can train and get better at. That doesn't really make sense to me.

People are just equipped better to handle it than others. I'm just kind of wondering if you could explain that whole thing. Thanks. Yeah. Now, anyone that has been a fighter pilot that's trained for this, I'm giving you a layperson's viewpoint on this. So if you have expertise in this, please call in because we'd love to talk to you about it. But they do high G training.

You can train for this. and they subject them to high levels of acceleration, usually using a centrifuge. So you've seen those spin around. And they design to these trainings to prevent G-induced loss of consciousness. And, you know, if you take a 90-year-old person and put it in there, they might be able to withstand two Gs. But a fighter pilot may be able to be able to.

to withstand i don't know i'm i've heard four to six gs and maybe more than that so um you know untrained individual can black out between oh between four and six gs and particularly if it's done suddenly um roller coasters are at most around three gs but i know i've felt a little woozy when i've done what is the one thunderhead at dollywood there's one turn on that oh no no no that's not right It's a Tennessee Torn80. There you go. When you do Tennessee Torn80, you do three loops. And when you go up, you look to the left and you see these three loops.

It's like, oh, shit. So you loopty, loopy loop. I have to do that. And it's about three Gs. And so you get loss of consciousness at different levels depending on your body's ability to withstand that. Now, I do know that they can use suits that exert pressure to the bottom part of the body. under high Gs to allow people to withstand greater G force because what happens is he's right. If the G force is from the head to the toe, blood is going to rush out of the head

and preferentially go to the legs and the feet and depriving the brain of blood is a bad thing and you'll get tunnel vision first and then you'll get loss of consciousness. Yeah, you can see that tunnel vision coming. Yeah, and that's right. able to survive G forces that are perpendicular to the spine. That's why we sit up. And when you

anyway, so that's what I know. Constant 15 Gs for a minute can cause death in somebody. Wow. So a trained fit individual wearing a G suit. This

statement I'm getting from Wikipedia. So we'll do more more research on this, but wearing a G-suit and they're trained and they're fit, and they can sustain up to nine Gs without loss of consciousness. And they work on the breathing technique where you tighten their abdomen, they tighten all their quads so all the blood doesn't go down to their body. Sure, sure, sure. And hell, at my age, when I stand up, that's too many G-forces.

You know, blood starts resting out of my brain. Tacey's seen me just bend over, and I'm going, going to faint, going to faint, going to paint, and I just bend over and put my head down, and it gets better. But basically, that is a different situation. That's where my autonomic nervous system that controls blood flow by contracting to increase resistance to flow, to pump blood up into the brain, is not fast enough. So when I stand up, my sort of fluid level drops, and what's supposed to happen is immediately your blood vessels start to clamp down. down to increase resistance. If you increase resistance to flow, you're going to increase pressure.

If you have the same amount of flow, and that will increase the blood pressure into the brain, you'll get good blood flow. Well, when you're an old asshole, like I am, you stand up and you start walking. All of a sudden, you realize very quickly that it didn't work. And so your blood vessels are just sitting there going, ooh. They're like balloons instead of vessels. Right. And then now the blood is rushing out of your brain into the...

the lower body and you start feeling faint. If you ever see somebody do that, by the way, don't support them upright. If they're going to faint, help them to have a soft landing, not crack their cranium. Protect their head and their neck. And then if you need to, if you don't have a chair nearby that you can prop their feet up on, sit in front of them, you know, with their feet at your, you know, on your chest, you know, on your chest. And then put their feet on your shoulders.

And if you do that, if you kneel in front of them and put your feet on their shoulders or just stand there and hold their feet up, the blood will rush back to their brain and they'll wake right up. But if you hold them up, blood will continue to rush out and they will have a thing called a pseudo-seizure. Well, it looks like they're seizing. And they actually are kind of seizing because the body really doesn't like that. Did you see a couple years ago, the Texas Motor Speedway, where they do NASCAR, they tried doing Formula One cars there. and they were doing testing and they just started testing

and like they were all feigning and well the first guy went around and and just ran off yeah and then the next guy I did the same thing and they're like whoa something something bad's happening here and they were pulling so many Gs going around that they were they didn't know they were going to have that me Gs is that right they were going out and they

wrecked there's like two or three in a row and they stopped it right so it's formula one on the NASCAR track oval yeah it's next we gotta look that up yeah it was Texas Motor Speedway because it's a huge like two and a half mile track i think so those dudes are burning it around the corners there and just start dumping and you could calculate i mean that's a physics question for first year physics you know given the slope of the curve at what you know you could and it's a calculus problem figure out where the um what speed they would have to go to hit nine gs or what speed they

would have to go to hit six Gs or whatever, you know. Way below that. And make sure that they always stay below that. So that would be really an interesting calculus problem. If anyone wants to calculate that for us, I don't know what the slope is of that track. It's not super high, which is why they're reckoned. It's not like Bristol where it's really pitched. It's a little flatter.

So they had to really pull hard because this is a simple calculus problem as well. or a physics problem, they will can't certain roads at an angle. And you can calculate that if you go the actual speed limit, let's say 45 miles, even if it's black ice, you will not skid either toward the curve or away from the curve. You'll do a straight line around that curve. And that's why they do it that way, and they'll have these speed limits. And if you'll actually go the speed limit on curves like that, even if it's covered in ice and it's a frictionless surface, you will not wreck.

It's pretty interesting. That's cool. So you can design a curve on one of these things the same way so that you don't have to pull a bunch of Gs because it's effortless to go around the curve. I was correct about John. He said it wasn't actually Formula One of his cart, which is still, I think they're open wheels, I think. Okay. Sorry about that, John.

We'll look into that. Yeah, we're close. That's interesting. All right. Another question about premature. Hey, Dr. Steve, it's John from Chicago. How are you all doing? Good, man.

How are you? That's great. Hope you're great. Hope your summer's starting off. Thank you, sir. I was listening to one of your last episodes on the podcast, and they were talking about, I think you were going over, you know, kind of like premature ejaculation or rectile dysfunction. And one thing I've always thought or heard, you know, rumor mill is that, you know, if you do. you know, try to treat erectile dysfunction with Viagra, and maybe you're too young,

or if you do it too often, that you could form a dependency on it. Is that true? Is there any validity? Okay, we're running out of time, but I have not seen any studies for that. As a matter of fact, most of the information that I've been made aware of, that there's no type of dependency on PD-5 inhibitors. I may say maybe mentally, mentally, yeah, but not physically. So those things are great.

If you don't need them, but you're having performance anxiety and you're having difficulty, we recommend having a Viagra in your back pocket so that you know that you'll be able to perform. And then most people don't have to perform. You remember that guy that we talked to that couldn't complete the transaction? And we said, hey, was it psychological or not? He wrote me back. And he said, since we had that discussion on the air, he hasn't had any problems. Awesome.

So we had identified that as being a psychological issue. We'll congratulate. So Scott's right. You can have psychological dependency on these things, but to my knowledge, there's no physical dependency. We don't recommend that you use it if you don't need it because really you should be using medications for what they're indicated for. But, you know, that's a free country. All right, Dr. Scott. Well, let's get out of here.

Thanks, everybody. Thanks. Always goes to Dr. Scott. Tacey. Hopefully Liam found his wallet. I can't forget Rob Sprantz, Bob Kelly, Greg Hughes, Anthony Coomia, Jim Norton, Travis Tepp, that Gould Girl, Lewis Johnson, Paul Ophcharsky, Kim Chickens, Amy from Kentucky, Chowdy 1008, Howdy Guplunk, Eric Nagel, Sean Pee, the Port Charlotte Hoare, the Saratoga Skank, the Florida Flusi, the St. Pete Barkeep Blower, the Dolly Museum Diddler, the Bullshoy Ballet, Bimbo, Percy Dunn. Roland Campo, sister of Chris, Sam Roberts, she who owns pigs and snakes, Pat Duffy, Dennis Falcone, Matt Kleinschmidt, Dale Dudley, Holly from the Gulf, Christopher Watkins, double Steve Tucci, the great Rob Bartlett, Adam Goldstein, Vicks, Netherfluids, Cardiff Electric, Casey's Wet T-shirt, Carl's Talipes, Equineveris, Tucker Dixon, producer Chris, Jenny Jingles, the inimitable. Vincent Paulino, everybody.

Eric Zane, Bernie and Sid, Martha from Arkansas's daughter, Ron Bennington, and of course our dear departed friends. GVAC and Fez Watley, whose support never one unappreciated, and let's throw Barry the blade in there as well. Rest in peace, my friends. Listen to our SiriusXM show on the Faction Talk channel,

SiriusXM Channel 103, Saturdays at 7 p.m. Eastern, Sunday at 6 p.m. Eastern on demand, and other times at Jim McClure's pleasure. Many thanks to our listeners. whose voicemail and topic ideas make this job very easy. Go to our website at dr. steve.com for schedules, podcasts, other crap. Until next time, check your stupid nuts for lumps. Quit smoking, get off your asses, and get some exercise.

We'll see you in one week for the next edition of Weird Medicine. Thank you, everybody. Thank you.