Weird Medicine: The Podcast - 528 - Schadenfreude is the Best Freude

Episode Date: October 28, 2022

Thanks and a tip o' the hat to Bob Levy for the title of this week's show! Dr Steve and Dr Scott discuss: Popcorn lung correction !vermect!n study: doesn't work...or does it? new solid tumor anti-cancer pill, Phase I trial oxytocin for dementia? etanercept for stroke symptoms a guy with distored junkal anatomy; can he impregnate another woman? flashes in your vision: get it checked out ASAP OTC remedies for small intestine bacterial overgrowth syndrome? Please visit: stuff.doctorsteve.com (for all your online shopping needs!) simplyherbals.net  (now with LESS !vermect!n!) (JUST KIDDING, Podcast app overlords! Sheesh!) noom.doctorsteve.com (the link still works! Lose weight now before swimsuit season is over!) roadie.doctorsteve.com (the greatest gift for a guitarist or bassist! The robotic tuner!) Please don't forget: Cameo.com/weirdmedicine (Book your old pal right now while he’s still cheap! "FLUID!") Most importantly! CHECK US OUT ON PATREON!  ALL NEW CONTENT! Robert Kelly, Mark Normand, mystery guests! Stuff you will never hear on the main show! Learn more about your ad choices. Visit podcastchoices.com/adchoices

Why can't you have a concert at the poultry farm? The chickens won't stop shouting free bird. Why was the sand wet? Because the seaweed. Why are mushrooms such great entertainers? Because they're fun guys. If you just read the bio for Dr. Steve, host of weird medicine on Sirius XM103

and made popular by two really comedy shows, Opie and Anthony and Ron and Fez, you would have thought that this guy was a bit of, you know, a clown. Why can't you give me? The respect that I'm entitled to! I've got diphtheria crushing my esophagus. I've got Tobolivide stripping from my nose. I've got the leprosy of the heartbound,

exacerbating my incredible woes. I want to take my brain out and blast with the wave, an ultrasonic, ecographic, and a pulsating shave. I want a magic pill. All my ailments, the health equivalent of citizen cane. And if I don't get it now in the tablet, I think I'm doomed, then I'll have to go insane.

I want a requiem for my disease. So I'm paging Dr. Steve. Dr. Steve. It's weird medicine. From the world famous Cardiff Electric Network Studios, the first and still only uncensored medical show in the history of broadcast radio, now a podcast. I'm Dr. Steve with my little pal,

Dr. Scott, the traditional Chinese medicine provider, gives me street crap. The wacko alternative medicine assholes. Hello, Dr. Scott. This is a show for people who had never listened to a medical show on the radio of the internet. You've got a question you're embarrassed to take your regular medical provider. If you can't find an answer anywhere else, give us a call 347-7-66-4-3-23. That's 347.

Pooh-Head. Follow us on Twitter at Weird Medicine or at DR Scott WM. Visit our website at Dr. Steve.com for podcast, medical news and stuff you can buy. Most importantly, we are not your medical providers. Take everything here with a grain of salt. Don't act on anything you hear on this show without talking it over with your health care provider. Tacey's not here PA Lydia's not here

We have new artwork by the way On our YouTube channel Check that out And on our Twitter You know whatever it is Twitter feed at Weird Medicine And it's got you and Tacey And P.A. Lydia on there. Have you seen it?

Yeah, I have. Okay So we'll autograph those When we send out stupid crap To people And don't forget If you buy something at Simply herbals.net, Dr. Scott will give you a fancy one of these shitty poker chips. Fancy poker chips.

That has mine face on one side. And that just says, thank you for your support fluid on the back side. I don't think I told him to do that. But we have some other actual poker chip sets coming out that are going to be awesome. And only a few of those are going to be made, and those will be probably displayed once. and then sent to the people who will appreciate them. But anyway, yeah, so if you buy something from Dr. Scott, do you need some more poker chips?

Not yet, but we've gone through a couple of them. Yeah, sure. Okay, very good news, good news. Simplyerbils.net. Check out the CBD or non-cbd nasal spray. Yep, yeah, we've got some Christmas specials or holiday specials coming. There you go, winter solstice special. Winter solstice special.

Check us out. Because he's, you know. Spatial. Dr. Scott is a pagan. Patreon.com slash weird medicine. If you want to hear something different but similar enough, go to patreon.com slash weird medicine. It's the only place that you'll hear the WATP crossover that was done for Sirius XM,

and I took out segments of it and put it up there. I can't put it out as a regular podcast. And then there's also, yeah, my thing at the, at the roast. My set at the roast is on there. Have you listened to it, Dr. Scott? Oh, gosh. God, you son a bitch.

I meant to. I was on my short list. See, that's some list. Your old buddy finally did something decent and you didn't even listen to it. And then cameo has been blowing up. It's been fun.

It's dirt cheap. That one, oh, I wanted to read this. I wish P.A. Lydia and P.A. Daisy were here. Let me read this to you, though, and to the listeners, because I was really touched by this, to be honest with you. And this is, so when you do a cameo for someone,

they can do a message back to you. And I did one for this guy, for his girlfriend, and she was taking care of her parent or something that had... Your mama. Yeah. They had Alzheimer's dementia. and felt guilty about putting her in a nursing facility after six years of doing all the care.

And we said, listen, you've stored up treasure in heaven. You've done God's work. You know, most people wouldn't do that at all. And you've got to do what's best for your mom. And if you can't do it anymore, you can't do it. So she texts her back, said, hi, recently. Oh, shoot, now. Well, now my phone rebooted.

Don't ever buy a Motorola, whatever. the shit this thing is. It sucks. It just reboots on its own for no reason. I didn't do anything to make it reboot. That's not good. You want it? No.

No, I was you, you want the info? Well, no, do you have my cameo on your phone? I recently did a cameo video from my... Oh. No, you sent it to us. Oh, okay. Yeah, you can read it. You can read it.

Well, here, you read it. You did it. That's your stuff. Well, all right. Well, this is going to be one hell of a show where we're just... It's still booting up. You read it. So it says, hi.

You recently did a cameo video for my mom from my boyfriend, John, regarding my transitioning, my mom to memory care. I am a doctor, too, which makes this transition hard. No, we didn't know. Thank you for your support. I played it again and again and again. And then Dr. Steve, of course, sends back, okay, you're the best. You don't have to say what I said. I just thought that was cool.

No, Dr. Steve's, oh, wait, I'm the best. what he says I did not I am the best you are correct so I'm glad Crystal's doing yeah

yeah yeah that was nice of John to do that for her it was he's a good boyfriend that's a tough that's a tough cost all of ten dollars

that's a tough was it damn that's that much yeah I think so you've gone up I don't know what way it's like it depends

of what platform you're on best ten dollars you can spend yeah I'm I mean it's almost embarrassing

but I like doing them so I don't want to charge people a lot of money for it. No, I think it's pretty cool. And, um, but anyway, but it's fun. It's cameo.com slash weird medicine. Hello, Dr. Scott. Hey, Dr. Steve.

Don't forget, uh, to check out Dr. Scott's website at simplyerbils.net. That's simply herbals.net. And I do want to say, uh, happy birthday to our, uh, network founder, uh, Mr. Cardiff Electric. So happy birthday, sir, to you. Um, okay. So thanks to James H. Uh, we have a correction.

A couple of shows back, we were talking about popcorn lung, and we were talking about it in relation to vaping and how we hadn't heard about it for a while, and that I thought that it was caused by the vitamin E oil that they were using in some of the knockoff vape things. Well, popcorn long is bronchiolitis obliterans. That part I knew, and I always thought that it was called popcorn lung, because when you look at the x-rays of people. It looks like little patchy infiltrates, looks like popcorn. Okay.

That was completely wrong. Oh, no, wait, we're on one. Oh, thank you. Yeah, that is not correct. So, although I talked to PA Lydia about it, and she agreed, it looks like popcorn in your lungs. The reason it's called popcorn lung is because they identified the disease originally among workers in a microwave popcorn factory. And the workers had breathed in this chemical called diacetyl,

which is a flavoring chemical used to make the popcorn taste buttery. And there are small amounts of diacetyl in some of the oils that people were using in the original sort of vape pens that people were purchasing around the country. And they felt that that was where that scare came from. Now, the other thing that had to do with vitamin E was a real thing, but it wasn't, didn't relate to popcorn lung. Vitamin E acetate was identified as a cause of acute vaping-related illness. So it's A-V-R-I, I think it's called. And vitamin E acetate is a condensing agent.

They use in these vaping products. and all of the injured lung fluid samples that they got and they did biopsies on people that were having this problem had that agent. So, you know, it was this sort of mysterious outbreak and they were vaping within the 90 days in like 2019. And we're not seeing this anymore because they're not wised up and are stopping using vitamin E.

You think, oh, vitamin C is good for, or vitamin E is good for you. Must be good to inhale. Let me take a toot off of my vape-pen man. And, yeah, no, that's not good. Not so much. So that was from an article in the journal Sirius. C-E-U, C-U, oh, my God, I'm having a problem today.

C-U-R-E-U-S-2019, vitamin E-acetate as a plausible cause of acute vaping-related illness. So I do appreciate James H correcting us on that because we were just talking off the hook, off the cuff. And, you know, what a surprise. We didn't know what we were talking about. Oh, and it's not, I'm doubly an idiot because it's right here in front of me. It's e-cigarette or vaping product used associated lung injury, which is E-V-A-L-L-I or E-V-Valley. is the name of the syndrome. And the reason I don't know it is because we don't fucking see it anymore

or because nobody's putting that shit in their vape pens anymore. All right. So that's a good thing. Yeah. All right. So that's what I have. We're going to probably be de-platformed after this next story. Unless we could use code words.

Okay. Let's use code words. What should the code word be? Hmm. Hey, about. The Big Eye. The Big Eye. So I'm looking at a, this is what piss me off.

Okay, here's a CNBC article. The Big Eye. Okay, it's an Ivermectin. A drug once touted as a COVID treatment by conservatives doesn't seem to work. Okay. Doesn't improve recovery much. Clinical trial of fines. Team of scientists, affiliate with Duke University,

I, okay, Ivermectin, I'm just going to say, I'm not going to, let's, you know, I don't like it when certain people call, like, people Carl Kevin, or people named Shulie, you know, stooly or duly and stuff. And, you know, I don't like that. So we're just going to say it. It's ivermectin does not meaningfully improve the recovery of people with mild to moderate COVID. So, yeah, okay, good. We have talked about this for a long time that we need frigging debt. on this thing because anyone who has been listening to this show for any period of time knows that we never recommended that people take ivermectin that but we didn't say people

were stupid for thinking that maybe it would have some efficacy there were reasons why people thought it might be efficacious against COVID-19 because it has known RNA virus antiviral activity and, oh, COVID, you know, coronaviruses or RNA viruses. Hmm, maybe it would have some effect. So all during this, when people were shitting on Joe Rogan saying he was eating horse paste, when he was prescribed, legally prescribed, and let me say that word so it comes out right, legally prescribed off-label by his physician, a huge, human drug called Ivermectin, which is used for a lot of things that's very well tolerated.

And Joe Rogan himself, if you listen to two second sound bites, you know, you could make all kinds of claims about Joe Rogan. But if you listen to the whole thing, he said, listen, I'm a dumbass. I don't know. This was prescribed to me by my doctor. I just did what my doctor told me to do. So we also explored the fact that there were 72. studies on Clinical Trials.gov

looking at Ivermectin. We were never those that were saying oh, you know of Ivermectin but I did say people who are rooting

for it to fail were part of the problem. Yeah, agreed. We want to root for anything that's offered any damn thing that helps. Anything to help. So we have

Molinupiravir, we have Paxelvid. Thank God. You've got outpatient remdesivir, although not very many people are using it. And we do have the

new Sotrova have the new monoclonal antibody. Okay. So we have stuff right on. Now, so we don't have to worry about Ivermectin so much because we know Molinapirovir works. It makes people feel better, faster. It improves productivity.

It only decreases hospitalization in the highest risk factor, folks, by about 30%. But then for those people, we have Paxlovib, which is around 80-something percent, preventing people going to the hospital who are at high risk? And are these drugs perfect? No. But they have been, they have proven efficacy. Now, back to Ivermectin because I am an empiricist. I'm interested in the science. So here is one from October 21st, 2022. And this is in Journal of the American Medical Association. This isn't some shite journal. It's as effective ivermectin versus placebo on time to sustained recovery and outpatients

with mild to moderate COVID-19. A randomized clinical trial. There you go. That's what we've been looking for. Thank you. So the question was, does Ivermectin for three days compared with placebo,

shortened symptom duration among adults outpatients in the U.S. was symptomatic mild and moderate. And what they found on that end point was that there was a decrease in symptom burden, but it wasn't statistically significant. Okay. So let me see if I can get the numbers here.

I've got it. There were 1,591 patients total. That is correct. Yep. But I'm trying to find. Oh, sorry. No, that's what you're fine. If you have the number, the medium time to recovery, okay, it was 12 days in the Ivermectin group and 13 days in the placebo.

group. Okay. So that was shown not to be statistically significant. However, they showed, they looked at some other things, too. And nobody, you know, when you get, ooh, conservatives, like, you know, Jimmy Dore is not a conservative. He's his left wing as you can get. And he was like, you know, we ought to at least look at Ivermectin.

Please look at it. And I'm no right-winger. And I'm, but I'm not. A left winger. Well, I don't know what I am. I'm left wing on some stuff. You're a swinger. You're a swinger.

I'm a pragmatist. I want to do what works. I'm an empiricist. Show me the data, and I'll agree with what you're doing. But so I, and I never promoted the use of Ivermectin. I never told anybody they should take it. I said, do what your doctor tells you to do, but that there are some very reasonable people who are at least looking at it

and they wouldn't be looking at it if it was just completely out in left field. Right. You know, no one is looking at Xanax for influenza right now, you know, because it would be nuts to do that. There were reasons why people thought this might do

something, but there is one interesting thing in this article. It said there were 10 hospitalizations in the Ivermectin group and nine in the placebo group, so, you know, all right. Again, not statistically significant. But the most common serious adverse effects were COVID-19 pneumonia, Ivermectin 5,

placebo 7. Again, not statistically significant. And let me see if I can do this properly. Venus thromboembolism, Ivermectin 1, placebo 5. Now, that, okay, you've got a large sample size. and very small numbers, you know, so you can calculate the absolute risk of having a thromboembolism compared to placebo. But it would be interesting to know if it was statistically significant. So I did a kai square analysis.

You'll notice they didn't, in this article, they don't say whether that's statistically significant. You know why? Because it almost was. It isn't quite. We consider statistically significance or statistical significance to be this thing called five sigma. And so that is, you know, five times out of 100 or one time in 20 that it would be due to chance. So that translates into a thing called a P number. It's a P of less than 0.05.

And the P of this was 0.08, which was approaching statistical significance. That means eight times in 100, this would be due to chance, which still means 92. times out of 100, it won't be due to chance. Now, so it may just need a larger sample size. Okay. Because this is a very rare event to have venous thromboambulism when you have COVID-19. So they had five, six out of 1,800, I think the total, or six out of 1,591. Okay.

So what does that work out to, percentage-wise? Not much. Echo, what is the percent of 1591 of... Shit, I asked it wrong. Never mind. Echo, don't answer it. 9,000. No, no, no, no, no, don't answer that.

Echo, stop. What, Echo, what percentage of 1591 is six? Six is 0.371% of 1,500... So, 0.3? Yeah, so 0.3%. Okay? Yeah. That's a very, so this study may not be big enough to be able to show whether this is statistically significant.

But I don't see anybody talking about this. What if, yeah, you do the molotivir, you do all this stuff, and if you got somebody that's at high risk, let's say they're immobile, that you throw in a little vitamin I and it will decrease the risk of thromboemabolic events. And by the way, for those that don't know, Venus thrombo embolism is when you get a blood clot in a vein and it moves. Okay. So Venus vein, thrombo blood clot, embolism, that thing's moving. Okay. And it usually is not, it doesn't move to a good place. It goes right into the lung.

Yeah. Okay. Rarely goes somewhere good. Well, it's nowhere good for it to go. No, no. So, and that causes a pulmonary embolism. So wouldn't that be something? I mean, this is really close to being statistically significant finding, and they're not, they're just, you know, all we looked at was, no, you looked at some other things, and this one thing was actually kind of impressive.

So I'm interested in seeing if they follow up on that. So we'll see. All right. But listen, I'm going to say whatever YouTube says I have to say, which is Ivermect. does not appear to have any efficacy for improving outcomes in COVID-19. Right. So don't, you know, we don't recommend it. Do whatever your doctor or health care provider says.

But there's some tantalizing evidence when it comes to thrombo embolism. I'm going to just say that by God right now. And these were in people who had mild to moderate disease. So, you know, who knows what we would see if in patients. with, you know, moderate to severe disease. Yeah. Okay. Wow, wow, well, interesting.

So I'm just interested in the data, and I am, it pisses me off when people just look at one thing and say, oh, well, he says, you know, Ivermectin, there's reasons why people would be interested in studying it. So he must be mega, man. Come on. Come on. looking at data in a real journal. Right. And it's interesting how this finding is completely glossed over everywhere. Say what?

But it's just the only where we're going to find out anything is to do this, do the research. Dr. Scott looked like a MAGA maniac, but he and I agree on this. Oh, gosh, yeah. 100%. All right. He probably is MAGA. Hey, Carla's got a good question real quick. Okay.

And it's about the blood clots. can you get a blood clot in your penis? And the answer is? Oh, absolutely, yes. Technically you can get anywhere. Thrombosis of the dorsal vein, that big vein on the top, well, the part that you can see, the top. And that's not good. You can get blood clots inside your penis in the caverna that, you know, the spongy places that fill up with blood when you get a giant meaty erection.

You could get a clot in there, too. and that, you don't have erections after that. No. I was going to say that's devastating. Let's see. Good question, Carla. Yes, very good one. Well, that was from,

thrombosis of the dorsal vein of the penis has a name. Does anybody know what it is? Don't look it up. No, you can look at it. I don't. I'll send a couple of poker chips to the first person in the chat who gets it, but you only have about a second. While we play interlude music.

That's not how you fix the blood clot in the penis, by the way. No. Okay, nobody got it. It's Mondor's disease. Hello, I am Mondor. Of the Mondortesticles of the island of Pinos. Anyway, yeah, dorsal vein thrombosis is a rare disease with pain and in duration, meaning kind of swelling, of the dorsal part of the penis

possible causes trauma yeah neoplasm excessive sexual activity or abstinence so either effing too much

or not effing enough yes I may end up there's a balance there is definitely a balance there isn't there differential diagnosis must be established with sclerotizing lymphangitis and

Peroni's disease, Doppler ultrasound is the imaging diagnostic technique of choice. Proper diagnosis and consequent reassurance could help dissipate the anxiety typically experienced by patients with this disease. Yikes. Yeah. No, thank you. That sounds awful. I know. So everything in moderation again.

Everything in moderation. Makes sense to me. Bowning too much. Mondeur's disease. All right. What else you got? It just sounds awful. I've got a couple things, a couple things, a couple interesting things.

Okay. If you look at my Twitter, you can see my Kai Square analysis. Oh, cool. I saw this earlier today. First patient receives potentially cancer-stopping pill in a new clinical trial. Okay, what the fuck is this? So that's pretty cool. So researchers at the City of Hope in Los Angeles, it's the largest

or one of the largest integrated cancer centers said they have a new cancer stopping pill and... Okay, by the way, this was published by City of Hope. Yeah, I'll say this is not... I didn't find this on... No, no, no, I know, but it's a phase one clinical trial. So they're tooting their own horn, by the way.

Right, yes, and what they're hoping is that they can use this. It works on stopping the cells from multiplicating and... Multipplicating. That's not even working. is it? Well, I don't know my multiple gate. I'll tell you what a lot. Replicating oponsize.

I said, do some cyphrine and the Gazintas. My gazintas. My gazintas. My gazintas. Two gazenta, four twice. My gazentas are firing on half a cylinder today. That's proliferating cell nuclear antigen. And it

plays an essential role in the replication and repair of cells. They thought it would be a less toxic cancer therapy. So they're targeting. these mutant cells while leaving normal cells alone. So I'm very excited about this. Well, they're showing some promise against working with promising against breast cancers,

prostate cancers, ovarian cancer, skin cancers, lung cancers. But what they're saying is that maybe they can use this in connection or conjunction with other existing chemotherapy medications, which would be. So you'd still have a great attack, but I think they were trying to use this for some of the cancers that have become resistant to therapy. Yeah. And so just some adjunctive therapies is what it looks like. Wow.

Wouldn't that be cool? Is this some kind of, it says here, don't you do the good manufacturing practice thing? Isn't that what you do when you make your thing? Mm-hmm. You have to get certified through that? Simpleros, yeah. She said, good, GMP facilities are manufacturing her medicine. Is this some kind of herbal shit?

Oh, I don't know. I didn't read that far now. I mean, how cool would that be if it actually worked? Well, you know, Dr. Stephen, and when I say herbal shit, I don't mean, you know, is it? No, I don't you mean. I'm just using that. No, I'm the one that uses the herbal shit, like flying squirrel feces. Yeah.

But that's different, of course. But, you know, most of these medications that you use in chemo, this chemotherapy age has come from, they're a derivative of some plant or animal. Oh, yeah, absolutely. Oh, yeah. Or antibiotics were all found by having fungal cells that were killing bacteria in, uh, petri dishes, and then you cut out the piece of the petri dish where the cells, you know, where the bacteria won't live. Right.

And then you run it through a bunch of different analytic tools to figure out the structure of whatever the hell it is that's in that petri dish that that mold created. And then you can take that and you can start changing it. Once you get the basic structure and you figure out how it's preventing bacteria from, replicating or how it's killing bacteria or how it's signaling the immune system, you can change a methyl group here or a hydroxyl group there and make it more or less potent or change the targets and do all kinds of stuff. So, yeah, all of the cephalosporins, you know, it's a broad group of antibiotics.

That's how they were discovered. Yeah, pretty neat. That's incredible. And penicillin was a mold. Yep, yep, yep, yep. And it, you know, killed bacteria. I don't know if it's true that they would actually take moldy bread and strap it to infected war wounds. I don't know if that's true or not.

Yeah, but that's the image. If that's all you've got, if that's all you've got, certainly would cross-off. Well, that's the image I have. And back in the beginning, penicillin killed just about everything. And then the stupid bacteria, we're like, well, F this. We're going to learn how to be resistant. And you know the one bacterium that has never learned how to be resistant? resistant to plain old penicillin.

There's a couple of them. Strip? Yeah. They're very good. Give yourself a bill. Excellent, Dr. Scott. So, yeah, we still use regular old plain penicillin for strip throat. All right.

Blind hogs stumbles across an acorn every once in a while. I am interested in this PCNA study. Yeah, hopefully it turns into something good. My understanding is the first patient that, took it, tolerated it very well. So now we just have to see if it works now. So let's remind everybody what a phase one clinical trial is. Those are small clinical trials.

You might have 20, 40 people in it, just to make sure that the thing sort of does what you think it's supposed to do, and it's not killing people or giving them horrible adverse effects. Then phase two might have 300 people in it, and you're looking for adverse effects. And then phase three, you could have, you know, 3,000 to 30,000. thousand people and you're looking for efficacy. By the way, I am in a phase three Pfizer trial for an influenza vaccine. That's MRNA. And I tolerated it very well and we'll just bug out see what happens. I did not get myocarditis. I didn't get anything. That's a good thing. Yeah. All right. That's a good thing. Are you done? I've got one more if you want it.

Okay. Well, sure. Yeah, we've got a good one. It's a, so this is good news. A derivative of the love hormone, oxytocin. Oh, good, yeah, which is a good thing. I love me some oxytocin. You can buy it over the counter at a compounding pharmacy, a couple of squirts up the nose, and then they have a bone session, and it's awesome. That's true. It's true.

It's the trust hormone. I'm only have to start taking a shot of that before I come in. It's not. Maybe so. We should give it to our audience, so they'll trust us. Oh, my God. It's associated with bonding of mother-to-child because when children, you know, when babies breastfeed, you have oxytocin release. And, you know, it's released during orgasm and all kinds of stuff.

So it's pretty cool. When you strutting your stuff. And when you strutting your stuff. And exchanging some fluid. Exchanging fluid. All right. Everybody take a drink. So the derivative of oxytocin.

And this is even the best part. Oxytocin reverses cognitive impairment in Alzheimer's disease. What? Yeah, no, this was incredible. I haven't seen this one. Yeah, this was incredible. For how long? This stuff is very short-lived in the body.

They just found out, so the, you know, the basic part of this, this is, this research is a derivative of the oxytocin is not easily accessed. It doesn't cross the blood brain barrier well. Yeah. And so what they were doing, they were, they were actually injecting. into mice and saw that it helped with dementia and Alzheimer's. So what these scientists have done is they're coming up with a different version of it that they can replicate and not have to put it into your brain directly, you know, where they can make it a pill or a liquid, a medicine, for lack of bad terms.

Are you sure it doesn't cross the blood brain barrier? No, no, it does, but it's not very well. Okay. Yeah, not, yes, sir, yeah. It does, but not the doses that they want it to. to make it viable for Alzheimer's. For Alzheimer's, they want a bigger dose. Right on, yeah.

So it's pretty cool. So that's good news. I would say the more oxytocin that we can release, yeah, I think that's good. That's another good reason to do your bonding with fluid. Then if you had Alzheimer's dementia and you jerked off that you would temporarily get better. Yeah, but you know what?

When you get to that age, the odds on getting an erectioner. That's true. So, but it kind of makes you wonder if you gave someone the intranasal application of the oxytocin, if it made them have momentary lapses of kind of being aware or being with us. So that's the good news. There are, have you heard about this stuff using a tannercept, which is, I guess, Enbrel, they use it for for Crohn's disease and stuff

like that. And they're using it for stroke patients. No, I have not. And they're actually injecting it into the base of their brain. And I don't know if this is BS or not. I want to see some good studies on this. But the

YouTube stuff is amazing. There's this lady. I think... No, no, I don't... Shut up. I'm not playing you. There's this lady in here that has a thing called a Phasia. Okay.

Okay, here we go. Let me see how I can find it. Okay, I'm sorry, everybody. This is terrible. There is a lady in here that has this thing called ephasia. It's broke as aphasia, and you get that when the left part of your brain, certain that the speech center is affected. And these people can't find words.

Worse than me. They have very difficult, very much difficulty finding words. And some of them can't find any words at all, although they can often say things like shit and piss and stuff like that. So those words must be stored somewhere else. Because I've seen people with Broca's aphasia, they just go, oh shit, oh shit, oh shit. And they can say that very fluently. They can't say anything else. I've got to find this lady. Okay, here she is. All right, let's try this. Let's see if this will play. that was reducing the effects of stroke. It isn't fully tested and is viewed cynically by many neurologists. Yes. But that hasn't stopped Linda, and the results are something to see. Yeah, this is pretty amazing. Here's this lady.

What's different? Ah. It's only been a brief few minutes since Linda Lumbera received that injection of Itanicept at the base of her brain. Clear. Clear. She's been tipped upside down to allow the men. medicine to flow into her brain.

Oh, my. Remember, this is stroke affected Linda just before the injection. Oh, a one. Two. Oh, my. Moments after the shot, she sits up. Really, broke his ephasia, they don't usually stutter like that or stammer. They just can't say it.

Okay. The words aren't there. So this is something a little different. You know, if you say count to ten and she can do it, but albeitly, insanely slowly, that's not exactly broke as a face. It could be partial. The change in Linda is something to behold. It's gone. Oh.

Hi. Come on there. Yeah, and that's something. What? Yeah. So, you know, you never know when they, this is 60 minutes. So I'm presuming that they didn't just pull a fast one on 60 minutes. Right. But I want to see the actual studies on that.

So, you know, the only thing I've... It's a potent anti-inflammatory. Right. Well, the only thing I was going to say is what I have seen over in Europe are the injection of stem cells into stroke-affected parts of the brain to regenerate brain, the brain itself. Yeah. But I have never heard of them using like an embryo into the... That's interesting. Let's see if they're, do they have any results with that stem cell?

Gosh, treatment. It's been a while. Because there's to inject stem cells everywhere. Yeah. Yeah. You know, I don't, let me see. Cardiovascular. Okay.

Chronic cerebral aspects of long COVID now. I don't care about that. Okay. Perispinal etanercepte advances as a neuropetic. Randomized controlled trial validating the use of perispinal etanercept to reduce post-stinel stroke disability has wide-ranging implications. Now, this is in expert reviews of neuroptherapy, not a turd journal. And let's see here. Okay. The dogma has been the simple, non-invasive way to accomplish this goal is not possible with many agents, including

biologicals, because they are too large to cross the blood-brain barrier. Various novel technologies to breach the blood-brain barrier have been attempted, but with a little success. Okay, so just inject it, you know, on the other side of the blood-brain barrier. Randomized double-blinded placebo-controlled trial administered a widely used antitumor necrosis factor biological, which are just basically insanely powerful anti-inflammatories and a etanercept given via peris spinal injection, which bypasses the blood brain barrier, turns this dogma on its head. This new trial holds most promise for stroke survivors as well as having implications for developing treatments, based on other large molecules that can't otherwise cross the blood brain barrier.

Sure. All right. God. Maybe there's something there. Let's hope so. That's not, you know, just some whack-a-doodle journal. No, and certainly we've all seen the devastation of those. Okay.

Okay, now this is the same guy. Now, he published a case report. Okay. And, yeah, it's a case report. Immediate resolution of hemispatial neglect. Okay, hemispatial neglect is an interesting one. It's when you have a stroke, say, on the left side of your brain, and then they will always look to that side,

and they don't think that their own hand is theirs. And you'll say, whose hand is that? You can hold it up and say, whose hand is that? And they'll say somebody else's. It doesn't feel like their hand. Their brain won't accept that it's theirs, which also tells you that there is a switch in your brain that says, this is mine, right?

Yep. Because if you turn it off and it says it's not mine, okay? There's some switch in there. So, yeah, that's very interesting. So those people,

that's very frustrating. They're very hard to rehabilitate because they really can't, they won't do anything with that side of their body that they're neglecting. And so he had immediate resolution

of hemispatial neglect. So I would like to see that. And I'd like to hold up some hope for stroke victims that maybe some of this stuff might help them. It would be wonderful. Because the brain and the central nervous system really is the last frontier of medicine. We don't know how any of it works. You know, we thought we knew how Alzheimer's works, and now they're finding other reasons why maybe it's happening.

So we'll, you know, more on that. I used to say 100 years for that, too. Maybe we're getting a little bit closer to 10, 15 years on some of this stuff. for the brain. It would be wonderful. I used to say 100 years for cancer, and now they're selling CAR T-cell therapy. I saw somebody the other day that had it.

Wow. Yeah. They're doing it by lottery right now. Oh, are they really? Yeah. So if you are eligible, for those that don't remember, car T-cell therapy is this chimeric antigen receptor T-cell therapy,

and what it is basically is they train your T-cells to kill your own cancer. And we talked about it years ago on this show. It's actually on our website at Dr. Steve.com. If you look at non-sudoscience cancer cures, there's the first case where it was used was against a woman with or for a woman. It was against a woman's cancer. She had terminal cervical cancer. My understanding is she's still walking this earth today because of this. And now they're just doing it.

But it's so not that, it's so rare that they're just having to do it by lottery. So if you qualify for it, they'll put you in a lottery. And if you get it, you get it. If you don't, you don't. Go back to regular treatment until it, we can get it to everybody. Pretty cool, though. That's incredible. Yep.

All right. Sounds good. All right. Let's see. Let's see what this guy says. Hey, Dr. Steve. My name is John. Hey, John.

Before we do that. Number one thing, don't take advice from some asshole on the radio. Thanks for taking my call. You're welcome, sir. I'm doing well. Yeah, thanks. I'm wondering, I went ahead and I accidentally knocked up my girlfriend. Okay.

And I've always been told throughout most of my life that the tubes that go from your balls into your dick, you know, where the sperm goes. Yeah. They're all tangled up, I guess, or something. and that my likelihood of conceiving is very low. Well, they were wrong. And she is saying about terminating, but if this is my only chance at conceiving, then I want to, you know, try to talk her out of it. But so I guess what I'm asking is what the chances are of this being my only chance.

Okay, that I cannot answer. obviously It's not zero It's not zero That's right Assuming that this is your kid That's the other thing You know

It might not be But The You know If you have a hypothesis That there are no White crows And you see a black crow

And you see another black crow And you see another black crow All of those things bolster your hypothesis But if you see one white crow It negates your hypothesis So the odds were very low, but they sure, like Scott said, they're not zero. So what are they?

Is this a one in a million thing? Or could you conceive normally? So how would you know? Here's how you would know. Go do a sperm sample. Go to your primary care. Say, I want to know what my sperm count is. What are the odds that I could conceive later?

And your girlfriend got to make this decision for herself. There's, yeah, there's moral arguments. In the end, she's just got to make this decision herself. And, you know, our opinion really doesn't matter. We're here for the science. We're here for the science. Yeah, our opinion doesn't matter. And really, kind of, your opinion does matter.

But it kind of doesn't, it, she has veto power. It's like when Dr. Scott and I were in business at the beer store, he was 51% and I was 49%. So if he wanted to run it into the ground, which he did, then I couldn't do anything about it. I had some input in running it into the ground, but I didn't have the final say. And that's kind of the same thing here is you have input. She shouldn't, I'm sure she doesn't want to make this decision in a vacuum. But I don't want you to be pressuring her one way or the other based on information that you don't know. So go find out. Now, if your sperm count is normal or close to normal, then you can impregnate somebody else. And then that takes that pressure off. If you're going to make a decision about being a father or being a mother, you do it for reasons that makes sense.

Right. And right now, you don't know the answer to that. So take away that unknown and find out. And then, yeah, if your sperm count is zero, Oops, might not be your kid, but if your sperm count is low, low, low, then, yeah, it might be unlikely that you would have the ability to have a kid later. But then you've got to say, I've got to commit to this kid, you know? That's got, you're going to have to commit. And if your sperm count is low, normal, or normal, then, yeah, you can just go impregnate somebody else.

And then you guys can have a different conversation. That makes sense? Yeah. Oh, shoot you. Okay. I'm always worried giving advice to people because this isn't really an advice show. It's supposed to be...

I don't think we gave him the science component. Go find out if you get... Yes, yes, yes. That's how you would know. Bottom line is, don't listen to what we say, but just go get your... That's right. That's right. Number one thing, don't take advice

from some asshole on the radio. And, but go do that tomorrow. Yeah. Okay? Yeah. Tomorrow... Take the guess we're out of... Okay, whenever you hear this.

Anyway, whenever you hear this, the first business day, go to your primary care, say, I need an order for a sperm count. And then if you want to send it to me, you can do that. I will be happy to look at it, and I will tell you, I will be happy to interpret the results for you in a way that's just your old pal who happens to have a medical degree, not as your doctor. All right? Good stuff, good stuff. All right. Hi, Dr. Steve. This is D.R. Perkins.

I'm a fellow that has been emailing with you over the past few years. Thank you for all the answers you've given me. You're welcome, sir. In the past, thanks for your support. I'm a surprise that you remember me because you guys must be polymaths. Okay, this guy, by the way, is the guy that came up, referred to us the vibrating air, air-shooting sex toy that you can look at at stuff.com. Gotcha.

Okay, it's down at the very bottom. I separated the adult stuff from the other stuff. Anyway, but that was D.R. Perkins. I always thought it was Dr. Perkins. I thought I was talking to another, to a colleague. Dr. Scott. Hey, hey. To be able to answer emails, and on top of that,

remember who the folks are to call you. Yeah. I would think that being on call and being a ham radio operator and all the things to do, he must be busier than a one-legged man in a butt-kicking contest. But to get to the... Yes, sir. Oh, sorry. Describe what happened after I noticed flashes in my peripheral vision. Okay, so we don't have a whole lot.

the timeline, but we got a little bit. He emailed me on the text message thing, I think, one of the other. He said, I'm having flashes in my vision on one side. If you have lightning flashes in your vision when you move your eye a certain way, it's either a vitreous detachment or a retinal detachment. Go see an ophthalmologist right then. So I wrote back to him and he said, well, they said I can get me in in two weeks. I said, no. No, no, no, no, no. Call them back and say you've got a Retinal or a vitreous detachment, they'll get you in today. So that's what happened.

So he's going to say what happened here. And no pain involved. Right. And I, therefore, was going to ignore it. He told me not to ignore him. So where I live, there's not very many ophthalmologists on call. I had to travel an hour and a half to find an expert to look at my eye. It's worth it.

and making a rather long story short. Yeah, not so short. It turns out that my vitreous humor is from old age shrinking and pulling away from the backside of my eyeball. So, yeah, so your eye, you think it's filled with water. It's not. It's like a jelly. It's a gel. And as you get, as you age, that gel will start.

to dehydrate and shrink. And when it does, it doesn't have anywhere to go. It will pull away from the retina. When it does, fluid will rush in, because there is fluid in there, that take up the place of where the jelly was adherent to the retina. And what comes with that fluid is all kinds of cells and debris, and you get floaters and stuff. It drives you crazy.

If I was a histologist, you know, somebody that looks in a microscope all the time, I would have had to have retired probably 15 years ago when we were. when I had my vitreous detachment. And what that can do is it can tear the retina. And in my case, it has not torn it yet. Cool. Good. Nothing for it because it's old age related.

Well, okay. So if you get horrible, horrible floaters, they can't actually do a vitrectomy where they take out the vitreous humor. Think about that. Your eyeball is a closed sphere, so they got to cut into your eyeball. It's going to look like a deflated balloon. Yeah, right. And we can talk about that someday, too.

I've seen one of those. And they suck it out, and then they put saline back in it. The problem is that there's an increased risk, of course, of infection. And if that eyeball gets infected on the inside, you lose the eye. So they don't want to do it unless they absolutely have to, because I was talking to my retinologist about it. He said, I'll do it, but I don't recommend it. It's like, okay, if you don't recommend it, I'm not doing it. I'm not going to force you into something.

I hope I'm pronouncing that correctly. Yes. Vitreous humor. Perfect. And I really don't have much of humor about it. And I have to ask you and Dr. Scott. You know, when you have guys like me, they call in and try to pronounce Latin words. No, it's just Dr. Scott.

Do your patients, in doing that, produce a stigma upon themselves, sort of like a Yankee trying to talk Southern? No, because I use plain words anyway. Physicians should be – health care providers should use plain words. And we've talked about this before, too. And thank you, D.R. Perkins. It was a great phone call, and I really appreciate the follow-up. And, you know, there might be somebody out there that will help. Yeah, exactly.

But even using positive and negative, we shouldn't use that. We use that differently. If you have a positive checkbook balance, that's a good thing. If you have a positive attitude, that's a good thing. You have a positive biopsy. That's not a good thing. It's not a good thing. It's a bad thing.

And, you know, we use these words differently than our patients do. This is an absolute true story. One of my friends, who is a physician, his mother called him and said, oh, thank God, my flu test was positive. She thought that was a good thing. Now, who would call up some little old lady and go, oh, by the way, your influenza test was positive, click. You know, what assholes.

But anyway, we do encounter that in this profession. People don't think about these things. And negative. I've seen people get upset because their CAT scan was negative, thinking that it was a bad thing. So, no, we don't worry about. But, now, there are D.R. Perkins, there are some funny things when people, instead of saying they have fibroids in their uterus, say they have fireballs in their universe. And instead of Myasthenia Gravas, say they have Monsignor Gravys.

I've seen that one. Or have a rotary cup instead of rotator. Yeah, rotary cup. I got my rotary cup. Tor my rotary cup. Tor my rotary cup. I have to wonder about so. That's still going?

Yeah. The doctor's attitude. towards the patient after that. No, nothing. We either find it amusing or endearing, but it's not. We don't expect our patients to know Latin and Greek and stuff like that. It's crazy. So I do, though, if I have a doctor that there's a word that means programmed cell death,

that's A-P-O-P-T-O-S-I-S-I-S. Have we talked about this on the show before? A little bit, but we have? Okay. But people will pronounce that apoptosis, and it's like, God, that just makes me cringe. I have a journalism degree. So typos, I see them and I have to fix them and that kind of stuff.

But apoptosis, it's not apoptosis. There's no Greek prefix that's apop. But there is a word toosis, P-T-U. Yeah, P-T-O-S-I-S, which means drooping. And apoptosis means falling away or falling. a way of leaves. Like you see trees, when the leaves fall, that's apatosis or apatosis. It just sounds better when you say apoptosis.

Yeah, I know. And if you go on, like, Webster's Dictionary, they'll pronounce it wrong, too. Oh, wow. They'll say apoptosis. They've got the computer anyway. So there you go. All right. Anything from the waiting room at hell.

Well, I've run out of steam here. Do we have you time left? Yeah, we've got a little bit. Yeah, real quick. Colin Carnes had a great question. I'll be the judge of that. Are there any over-the-counter herbal supplements, dietary supplements, to help treat SIBO? Now, he did take our advice, I think. Okay, tell them what, so we're talking about small intestine bacterial overgrowth.

And this one, we don't have time enough, but you throw out something. Yeah, but real quick, yeah, obviously the Fodmap diet can help, and there are some things that can help. FodMap is where you eliminate certain sugars. the things that the bacteria eat. Yeah, that they love. And sometimes it's a lot of foods you would never suspect they're really healthy foods otherwise. So there are some over-the-counter supplements.

If you'll Google them, you can find some, but there's a gazillion. Well, give them one. I can't think of one. Oh, for a second. You were just temporizing. No. Okay, probiotics.

Yes. Well, you know, probiotics can help. But there's actually some natural antibacterial supplements you can take, but they're all brands. Really? Yeah. Let me look at it. Barberry has been shown.

Barberry. Barbarry, B-A-B-E-R. What hell is that? I don't know. Oregon graperoot, golden seal, have all been shown to help treat the bacteria and that are influencing it. Get out of. Here's their data on this. Oh, God, yes.

The date is compelling. Data is compelling. Herbal therapy is equivalent to Riffamaxon, the treatment of SIBO. Ripefaxon. And it's sons of bitches. So, there you go. Well, that's because you're an idiot. So which herbal things are equivalent to Rifexman?

Now, listen, this is a big deal if this is real. It is, yeah. And I just literally, I just literally found it. Give me two seconds of them. I'm scrolling down to the bottom of the, for the, for the actual. Because what they've shown... Okay, I'll just do it. My God.

I'm looking. I'm looking. I can only type so quickly. But there are herbal formulas, and I'll tell you, it's actually in the NIH National Library of Medicine. Okay. So it's PubMed. This is a real deal. Okay, that doesn't mean that it means anything.

You can get listed in PubMed and be the shittiest... Oh, gosh. Here we go. Now, now it's in PubMed. It's not worth it. You have to look for the quality of the data Okay, here we go Okay, cinnamon, thyme and pomegranate

Oh, get out of here with this Oh yeah, no, Simmons is very good Time, time oil and oregano Both have been shown to be anti-bacterial Parsley, sage, rosemary, and thyme, right? Yep, perfect sprinkle it on your pasta Or your Simon and Garfunkel song

Let me see Okay, we're going to do some more research on this We will get an actual real answer Because this is not good radio And you and I just looking at the internet Colin, I'm sorry, but the answer is yes And I promise you next week I'll have some very good ones I'll tell you what, Colin actually call in

Yeah, that'd be good call them calling Yeah, call in the, or send us a voicemail. Hey, Kim Chikins is here. What's up, Kim? Hello, Kim. Hi, Kim. Do you know anything about Ova Ersi? Oh, that's Bear Berry.

Is she an actress? That's Bearberry. Oh, my God. Okay, we're getting out of here. This is getting ridiculous. All right, for those who are in the waiting room, we're going to play a couple of tunes. Everybody else, we will see you soon. Thanks to everyone who listens to the show.

show and listen to our SiriusXM show on the Faction Talk channel. SiriusXM. Channel 103, Saturdays at 7 p.m. Eastern Sunday, I think at 10 p.m. Eastern, but on demand. That's the best way to listen to it. If you want to hear the WATP podcast crossover with weird medicine, there's two ways to do it. Go to your SiriusXM app and listen to that episode on demand. It's very clearly demarcated. Or you can go to our Patreon, patreon.com slash weird medicine, and it's there. It will never be a regular podcast. Sorry, can't do it. Thanks to movie Messiah, thanks to Carla Finch,

thanks to Sean Patrick and Bob Bobbington and Kim Chickens, all the other people in the chat room who I can't see right now. So thank you all for hanging out with us. Many thanks to our listeners, his voicemails, Topic ideas, make this job very easy. Go to our website, Dr. Steve.com for schedules, podcasts, and other crap. Until next time, check your stupid nuts for lumps, quit smoking, get off your asses, get some exercise. We'll see you in one week for the next edition of your medicine.

Thanks, everybody. Thank you.