Weird Medicine: The Podcast - 532 - Bladder Parasites Stink
Episode Date: November 28, 2022Dr Steve, Dr Scott and Tacie discuss; Plastics are everywhere Bladder calcification from a horrid cause Just ferment everything Hops and dementia What's a partial nephrectomy? Bob's Rash (TM) M...ultiple Sclerosis Post-coital spasm of the urethra and how to treat it (maybe) Please visit: stuff.doctorsteve.com (for all your online shopping needs!) simplyherbals.net (now with NO !vermect!n!) (JUST KIDDING, Podcast app overlords! Sheesh!) roadie.doctorsteve.com (the greatest gift for a guitarist or bassist! The robotic tuner!) Weird Medicine: The Podcast is sponsored by BetterHelp: betterhelp.com/medicine (Give online therapy a try and get on your way to being your best self!) Also don't forget: Cameo.com/weirdmedicine (Book your old pal right now while he’s still cheap! "FLUID!") noom.doctorsteve.com (the link still works! Lose weight now before swimsuit season is over!) Most importantly! CHECK US OUT ON PATREON! ALL NEW CONTENT! Robert Kelly, Mark Normand, the O&A Troika, Joe DeRosa, Pete Davidson. Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices
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What does Aladdin wear to the office on casual Fridays?
His blue genies.
Why can't summer and winter vacation together?
Because summer's always looking for a hot time, but winter just knows to chill.
What's brown
And sounds like a bell
Dong
If you just read the bio
Host of Weird Medicine
On Sirius XM103
And made popular by two really comedy shows
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You would have thought that this guy was
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Why can't you be?
Give me the respect that I'm entitled to!
I've got diphtheria crushing my esophagus.
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Hello, Dr. Scott
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Hello, Tacey.
Hello.
This is a show for people who had never listened.
That was very seductive.
Hello.
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We've had a couple go out.
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We just had Pete Davidson on.
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That's the golfer.
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That's great.
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that. That's fun. I had
high-pitched Eric say
Christmas greetings
to Beck and Liam
one year. It cost me
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and probably for the holidays I'll make it
even cheaper than that. Oh, good.
Yeah. Camio.com
slash weird medicine. And also
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There's going to be an awesome show there.
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is in your future.
All right, very good.
But don't forget to check out Dr. Scott's website at simplyerbils.net.
That's simplyerbils.net.
And Tacey, you'll be happy to know I'm not going to announce Mr. Cardiff's birthday today.
However, it is his wedding anniversary today.
So congratulations to Mr. Cardiff.
Aren't we funny?
Aren't we funny?
To his wedding anniversary.
Congratulations, sir.
The owner of our network.
Sounds good.
All right, very good.
Hey, we got some good response from the Vinny Tortrich thing.
Enough clapping.
From the Vinny Tortrich thing last week.
And I'm doing some deep diving on some of this business.
You know, he schooled us or schooled me pretty good on a lot of stuff, particularly the estrogen content in plastic.
I was not aware of that on any level.
So I still would like to see if, I mean, I know we don't want any, but we don't want any insect parts in our oatmeal either.
And we've got to deal with some.
Is there any clinical relevance to that?
Because if there isn't, then it's like it's interesting.
And then it becomes almost like when the governor from Minnesota.
Governor.
Well, from Minnesota.
Jesse Ventura.
Thank you.
It's the dementia kicking in.
The first thing that you lose is being able to name things today, so we'll just get rid of.
What about finding your keys that are under your name?
That is funny.
Yeah, I was looking for my keys.
I got Tacey's iPad out to search for my keys using the little Apple tag things, and they were literally, it wasn't even six inches from me.
Oh, goodness.
I don't know what's wrong with me.
I think it's called too much good.
too much going on. Maybe. I hope
that's what it is. I still seem to be
high functioning.
I'm
so I'm not so worried about the dementia
kicking in, but it is, I am
having some trouble with things like
naming things and stuff like that. Anyway.
It's lack of sleep. Yeah, that's a big part
of it. But Jesse Ventura
was talking about how there's
fluoride in... It's one of the
ingredients in Prozac. And it's like
Yeah, there's three fluorine, or I mean, fluoride atoms, fluorine atoms in Prozac, fluoxetine.
But they're atoms.
They're not ingredients.
It's not a cake.
It's not like you take a bunch of fluorine and then you take some carbon and some hydrogen.
You all mix it up and then you've got Prozac, right?
you have fluorine atoms that are drawing electrons away from the rest of the molecule
that makes that part of the molecule more chemically active.
That's all it is.
And, you know, he was saying that that is evidence that putting fluoride in the water
is trying to pacify the populace.
Now, the vast majority of water in this country that is munific,
Spill has fluoride in it.
Does this seem like a pacified fucking populist to you?
No.
So it's that kind of stuff.
So what I really want to know is does it make a clinical difference?
Are people, because they're drinking out of plastic bottles, are guys getting growing, you know, gynical mastia?
Are they getting breasts or women having a monarchy earlier?
In other words, you know, early periods earlier, stunting people's growth, that kind of stuff.
Is it doing that?
Is it causing an increase in estrogen-sensitive cancers like breast cancer or uterine cancer?
And if it isn't, is it doing anything at all?
Is it in, you know, yeah, we can detect it, but is it something?
So I'm looking into that.
And then the business about soy still bugs me.
I don't know that I'm buying it completely, are you?
Well, no, I'm saying, you know, I don't know that soy.
is an abomination.
Now, Vinny isn't here, but I would like to have him back sometime, and what we'll do is I've done a little bit of research on this,
looking at health effects and adverse effects of soy.
And so we'll see, you know.
It was funny, though, that night, though, Tacey and I, we were cooking, and we looked, I looked at Tacey.
I said, well, Vinny would be horrified because I made fried tofu that I fried in canoom.
alone.
Lord.
And what else did we have?
There was something else we call it a Tortorich special.
I can't remember what it was.
But anyway, check him out at Vinny Tortorich.com.
He's no longer the world's angriest trainer.
He is now the, you know, just trying to get people to eat right.
And it was fun having him on.
We're supposed to have him on for 15 minutes and it was 45 minutes into it.
Yeah, he was awesome.
It just went by so fast.
So anyway, okay, check him out.
So I had a couple of articles from last week.
I wanted to bring a gross thing in.
This one was from New England Journal of Medicine.
It says, what's worse?
Well, this is, okay, the image is from the New England Journal of Medicine, but the article is not.
It says, what's worse than a parasitic worm infection?
A parasitic worm infection that causes a calcified bladder, a condition that probably feels every bit as uncomfortable as it sounds.
A 43-year-old man in Cutter found out just how painful a calcified bladder can be.
He had blood in his urine and pain when he micturated.
It doesn't say that.
It says peed, but I refuse to say that.
For a month before the doctors diagnosed him with an infection by the parasite.
Do you know what it is?
He's in the Middle East, and it's in his bladder.
Do you know, Scott?
No.
Okay.
Chistosoma, or schistosomiasis, which is transmitted by fresh,
water snails.
Okay.
The man's infection was located near his bladder and ureters.
Those are the tubes connecting the bladder to the kidneys.
And eggs of the parasite ended up in the wall of the man's bladder.
And his body's immune response caused those areas of the bladder wall to become calcified
in a pattern known as egg shell calcification.
Well, this kind of calcification as a result of schistosomyasis is not rare.
It's unusual for Dr. Cia patient with an entire bladder encased in calcium.
since it takes years for that much calcium to build up inside the body.
So that was a hell of a damn thing.
Dang.
Yeah.
He probably was infected by the parasite as a child, and he lived with it for at least 30 years before they prescribed a treatment, which I guess is, let's take your bladder out.
And sorry about that.
Now, if you take someone's bladder out, you can make a sort of makeshift bladder out out of part of their intestine.
It's called an ilial conduit.
where the ureters actually empty out from the kidney,
though the tubes coming from the kidney
will empty into a diverted piece of small intestine
called the Ilium.
And, yeah, that can, you can, you know,
you make a little stoma out of the side of the abdomen,
which is a stoma meaning mouth or hole,
and you just hook up a bag to that
and you pee out of that instead,
but it can be done.
So if you lose your,
bladder for whatever reason.
All is not lost.
Your life just becomes a little bit
more challenging, yeah.
Okay, and there's the other one, another one
from an image from the New England
Journal of Medicine. Nothing ruins
a day at the beach, quite like getting
a fish bone stuck in your eyeball.
Unfortunately, that's
what happened to a beachgoer visiting the
Red Sea in 2015.
The 52-year-old tourist
was swimming in the Red Sea
when he collided with a school of fish.
Oh, no.
This is a dumbass
fish, usually they'll get out of your way.
You know, they swim around you.
Not long after the incident, the man developed a swollen and droopy eyelid that wouldn't
heal.
The doctor's visit revealed that he had an area of inflammation called a granuloma on his
eyelid.
That's just a collection of fiber and white blood cells, basically.
And the patient underwent surgery to connect the issue, but the granuloma wasn't the only
thing doctors removed from the erstwhile swimmer's eyeball during the surgery.
Eustwald means he used to swim.
That means he's never going to swim again, basically, is what they're applying.
Two tubular structures were also removed from the man's eyelid, according to the report
republished in New England Journal of Medicine in 2015.
2015, a biologist was called in to examine these strange specimens, which you can do when
you're at like a really highfalutin university, which turned out to be the jaw bones
of a half beak, a fish that dwells in shallow coastal waters.
Dang.
So there you go.
In his eyeball.
Yeah, well, I was actually in his eyelid.
I pulled it because it said eyeball and then it was clickbait.
Oh, Lord.
Because medical journalists or whoever make these lists don't know the difference between an eyelid and an eyeball.
No.
So there you go.
That was left over from, I was supposed to do that last week when Vinny was here and he was just so interesting.
So he was a good one.
You know, I bought a whole kit on.
And I, it's so funny.
I bought a kit of, you know, I've been getting into fermented stuff.
So I made fermented pickles, which were amazing, by the way.
Well, three, one, since COVID started, how many different things did he get into, taste?
Let's eat baking.
I mean, it's enough is enough.
And I didn't not know that that, what I was getting into when we got married.
It was pottery at that time.
And then it was winemaking.
Yeah, she, that's right.
We got married.
Yeah, that was winemaking.
Because I invited her to pottery class.
And she came, she didn't realize that was just one of 10,000 things that I did.
She thought that was, oh, this is that doctor who's the pottery guy.
No, it's the doctor who's the dilettant.
Yes, you're like, your face really should be.
I am a fucking dilat.
ADHD.
Yeah, that too.
Times 47.
Well, yeah, no, yeah.
That's why I was stupid Steve growing up because I had.
ADHD and they didn't know what that was.
Well, now you're really smart, Steve.
Yes, very smart.
So, we've been through poker.
Yeah, yeah.
Yep, remember that.
I remember that.
Wine.
Taught poker.
Um, Moonshon.
Yes.
Yeah, we made moon.
Are you writing this down?
You have a list?
You're looking at something.
No.
Okay.
Okay, she's doing this from memory.
Okay, fair enough.
Wine.
Moon Sean.
Yes.
What, what, oh.
Beer?
Well, then liqueurs.
Lecores. I was pregnant
during all that, so I didn't.
I remember those days.
And then we got into making
sausage with the lynx
and all that. Oh, yeah. And smoking them.
Smoking them.
And I eating them.
And then we moved.
And then we started having kids, and then kids
became the hobby for a while.
You left out ham radio, by the way.
And the whole time it's been
consistent ham radio.
Painting his dolls.
And then they are not dolls.
And then you're forgetting
And the big thing, the Moog.
Oh, yeah.
The synthesizers.
Oh, yeah.
Then the mode.
I forgot about it.
Oh, and then the thing that you're sitting in right now, the studio.
Which would be a great Christmas tree closet for me if you think about it.
Think of all the stuff I could keep in here.
You know what?
We maybe could do something like that.
If we moved the studio somewhere.
Oh, yeah.
Let's do that.
That has air conditioning and stuff.
But anyway, so, yeah, so I started doing this fermented stuff, and I thought it would be good for, you know, good for my gut and all that stuff.
And I, if I could get the kids to eat it.
So I used to make yogurt and things.
So I made the pickles, and I made sourcrow, which tastie ate.
I didn't like it.
It wasn't sour enough for me.
And what else did we make?
I made, oh, I made that fermented hot sauce that is kick ass.
It is good.
It is good.
Oh, my God, is it good?
Good stuff, yeah.
And that all started because I had a Tabasco pepper plant, and I never planted one before.
And they're these beautiful little peppers.
I think we talked about it last time.
And they're all different colors, beautiful.
They're all perfect little things.
And I read, well, I should make Tabasco sauce out of that.
Well, to do that, you have to ferment the shit.
So that means you've got to go buy all this stuff to ferment it.
And it wasn't that big of a deal.
Well, anyway.
So I said, I am going to, for my hippie friend, Dr. Scott, I'm going to make kombucha.
So I got a starter kit, I got this thing, and I had this fantasy that I was going to supply you with all the kombucha that you would ever want.
And then today, so I'm almost ready to bottle it, my first batch.
And Scott comes in, and I'm like, hey, Scott, do you like kombucci?
She's like, eh, not that much.
Yeah, which is, it's a requirement to be a hippie, actually.
It's absolutely a requirement.
So probably should I ask first before I went to all this.
Well, why would you think so?
He's got a Grateful Dead t-shirt on.
He's got the man bun going.
Well, he's a vegan.
He goes with it.
He likes kimchi.
I remember you told me you like kimchi at one.
I do like kimchi.
And I'm sure that your kombucha will be fabulous.
No, I don't know.
None of it's fabulous.
It's an acquired taste for sure.
No, it's disgusting.
I'm looking forward to it.
But when you talk about, let's, probiotics for a second.
Oh, yeah, heck yeah.
You know, the gut biome has a huge impact on, it's looking like even crazy shit like memory and stuff.
But certainly mood and certainly when your gut is working, you know, you can't separate your mind from your body.
But when your gut is working, your mood is going to be better, those kinds of things.
and you could go buy those capsules
that have all these freeze-dried bacteria in it
and it'll be two or three strains of lactobacillus
and, you know, bacteria are so stupid
and simply you can freeze-dry them
and then you put them in water, they come back to life.
It's ridiculous.
But there's also yeast, good yeast in there as well,
like Saccharomyces, which is basically brewer's yeast.
So, and you might get 39 billion colonies out of that
and maybe, you know, 1% of those will survive.
One thing at kombucha is, you know, is trillions of bacteria in there and lots of different colonies, you know, just multiple, you know, colonies beyond what you can get in the store.
And they, you know, they're all beneficial.
So, or at least they're benign.
And they work well with your gut.
I guess that's what I should say.
I don't want to make any medical claims about it.
But anyway, so I'm fascinated by it.
I'm going to make it.
And then I'm sure after a while my starter, which is like a sourdough starter,
just more shit for the garage.
There's a thing that lives in it that's like the sourdough starter.
You ever made sourdough bread?
No, but I used to make sourdough bread, and it broke my heart when the stupid starter died.
And I just, well, fuck it did.
I never made anymore.
But this thing has a thing in it called a Scobie.
It's a symbiotic culture of bacteria and yogurt.
And one of our listeners was the one that told me about this.
And it's a little floating alien that lives in there.
And that's what makes the kombucha.
You know, it ferments all this stuff.
Okay, well, I'll call that person back later.
But anyway, it's fascinating.
The whole process is fascinating.
I don't know how in hell somebody did this in the first place without, you know, just effing it all up.
But anyway, it's a whole thing.
There are kombucha brewing stores.
There's a whole section in the grocery store that I never realized was there.
So anyway, I'll try to make something good.
I'm going to make raspberry cherry kombucha.
Oh, cool.
If you like it, fine.
If you don't, I'll find somebody that will drink this damn shit.
Anyway.
I'm sure it'll be good.
That's my newest hobby.
Anyway, all right.
You got some stories?
I love it.
Oh, yeah.
We've got a couple stories.
We could talk about how we're going to do our turkey this.
sure. I'm not so sure that I can beat
the kombucha. Oh, it's
not as terrible. It's boring. Nobody
cares. You know, when I'm
sitting there talking about it, this is what I
hear in my head. You know, you are one pathetic
loser. That's what I hear.
I know, I know. I love it.
Well, so we'll keep... No, I'm just kidding.
We'll keep things on the...
Or I hear this. This is the other thing I hear in my head.
Oh, wow, that is very interesting. Please
tell me more.
I understand. I feel your
It's our holiday show.
We're recording this the day before Thanksgiving.
We're going to keep it live.
We're not going to give everybody all that shit that Vinny gave us last week,
brought everybody down.
We're going to pick everybody up for the Thanksgiving holidays, right?
Well, I think he gave people hope that you can eat and have a better life.
We're going to eat like motherfuckers as we are.
And enjoy it.
And I am dry brining my turkey, and I will post a picture of it on Twitter.
I quartered it last.
Last night, took the breasts off, took the legs and thighs and then the wings, and then took all of that off, took the carcass.
I would have normally made stock out of the carcass, but I just said, screw it, I'll cheat when I make the gravy.
But you could do that.
You take the carcass and the neck and all that stuff in there and put it in water and bring it, you know, boil it down to about 50 percent, strain it, and then you can make gravy out of that.
But I did not do that.
I wasted the carcass, but I dry brined it.
So it's got tons of salt over it.
It will not taste salty when it's cooked.
And all those juices are now being driven into the center of the turkey, and they will stay there.
Right?
And they will stay there even after it's cooked.
So I'm going to sear the skin and then bake it for like 20 minutes in a 450-degree oven.
And then the dark meat can go back in and stay in for a little bit longer.
You want the white meat to be 160 degrees.
The dark meat should be about 180, which is really hard to do if you're cooking the thing all at once in one big bird.
Plus, when you've got a giant spherical sort of bird thing, it's hard for the heat to get into the middle.
It takes much longer.
So anyway, all right.
Perfect.
There you go.
Try dry brining your turkey next time.
Turkey talk with Dr. Steve.
Well, it is the day before Thanksgiving.
Of course, it's going to come out.
The day after.
The day after.
Thanksgiving.
That's okay.
Everybody will be hung over with turkey.
Well, that's because you're an idiot.
Well, hopefully, people will be still celebrating their things.
That's right.
Well, they could file that for next year.
The Thanksgiving weekend as well, or for Christmas, maybe.
Okay.
The next big holiday.
So I've got some good uplifting news.
Okay.
You guys are going to love this.
So beer, keeping with our holiday thing.
Already paying attention.
Guess it could be the key to preventing Alzheimer's.
Really?
What I do know that what beer does is it makes you stand in front of the stage and yell the F word at the bass player for an hour.
Say crazy stuff.
At the isotopes concert.
That's what beer does.
I'm pretty sure that's not the only time you've done that.
Yeah, what was the other?
Okay.
Well, also what it does is make you stand up on the table and yell.
the F-word at the guitar player at the Indigo's concert.
Yes, Indigo's.
I could not think of that name for anything.
Yeah.
Oh, my God.
So researchers have found a, or researchers suggest in a recent study that the hop flour extracts found in beer
could hold the key to preventing Alzheimer's, which is a form common form to mention.
Woo-hoo!
So I should make hop-y beer.
Hop-combocha.
Oh.
Yeah.
Now, that's a good idea.
why hops you may ask yeah why hops what's the deal what are they got generally acting as a
stabilizing agent in beers but you know that's i think that's why they started using hops
a thousand years ago to transport things yeah yeah yeah sure yeah and the other you know makes
total sense and i bet i mean their beer back then didn't have much fizz to it couldn't have had any
it would be like the primary fermentation i i can't imagine how they would do a secondary fermentation
back then.
And unless, well, it would be very difficult.
Yeah, yeah, I wouldn't think so.
But, yeah, so that's what they're saying is that the hops, the state bludging agents,
and four common varieties of hop flour extracts to determine whether they would help
prevent protein clumping affiliated with Alzheimer.
Okay, so this was in Test Tube.
Yeah, yep, yep, yep.
Okay.
So hop varieties is we love Cascade is probably my favorite.
Tetanong Summit hops, which,
It's pretty familiar.
I'm not familiar with S-A-A-Z.
I don't know.
If we had P.A. John in here, he would wax eloquent about it, even if he was just lying.
Even though he doesn't know Jackson.
He doesn't make up stuff, but he would sound good.
Yeah, now he's just stupid P.A. John again.
So anyway, so there's no.
Yeah, we've not got a single cause identified Alzheimer's as far as just one simple thing.
It's, you know, there's multiple factors, genetics, lifestyle environment, et cetera, et cetera, et cetera.
But what they're saying is that the hops may disrupt some of the clumping mechanisms, you know,
that might be causing some of the clumping that cause Alzheimer's, yeah.
Well, I'm going to...
So we're going to...
I've got to get some hops.
I'm going to put some in our back to this.
What about alcoholic kombucha?
Yeah.
Yeah, you can put alcohol in.
Is it worth drinking?
Oh, yeah.
Totally.
There's what you need to make, Scott.
Yes.
Okay.
I was just thinking of it.
Well, you could just put vodka in.
A little tequila or a little vodka, I should be fine.
Oh, okay.
Or you could just do that.
Or I'm thinking maybe hops now.
There is like 0.5% alcohol in it.
I'll say there's probably a little bit of alcohol in there isn't.
Yeah, yeah, a little bit.
Interesting.
So what do you think about that?
That's good news.
I think that's awesome.
That's good news.
Yeah, I want to know more about that.
So, okay, so let's talk for a second.
They've got this preliminary data in vitro.
We know hops are safe, basically, for consumption, at least in the doses that we do, that we use.
So how would we determine whether hops in humans actually decreases the incidence of Alzheimer's disease?
So we would eventually, if we want to prove it, do a double-blind placebo-controlled study, right?
Now, how do you do?
How do you, what dose do we use?
We don't know.
We got to make something up.
So you have to, you come up with a dose, presumably one that's safe.
Yep.
And you give it to a bunch, say, 30, 40 people and make sure they can tolerate it first.
That's your phase one trial.
Then, are you okay?
Yeah, I thought I was going to seize them.
I'm sorry.
Okay, I was just trying not to steezing over there.
No, gosh, no, I was so rejoined with the.
Steve Scott's vomiting over here.
The hop talk is making me happy.
I would stop talking.
But anyway, so you would do that, make sure that, because we don't know what
the dose would be. We have no clue.
Now you design
a study where, you know,
and we've talked about this enough on the show, I don't have to go
in a lot of detail, where you give a thousand
people the hops pill
and a thousand people the placebo pill.
There's no ethical reason
not to do that because we
don't have any real reason to think that
the hops thing is a standard
of care. If it were,
then we would have to come up with a more
ethical way to do it. In other words, if we were
depriving someone of a of a treatment that we know would help them, then you can't really
give them a placebo, right?
So, but in this case, it would be fine.
And then now what?
You've got to follow them for decades.
That's the problem with this.
That is the problem with that one, yeah.
So you'd have to have funding, and it would have to be the Hops Association, probably,
whatever that is.
Yeah, it would have to fund this thing.
And then you would have to follow these people over decades.
Now, it wouldn't cost that much money to do this.
This would not be a billion-dollar thing.
Now, at the end of this, if you would have to decode the codes on the people's little dose packs to see who got hops and who got placebo.
And then you have to do basically just a statistical analysis, like a kai square analysis,
to determine whether there was a statistical significance
between the treatment group and the placebo group.
And was it positive?
In other words, it could be statistically significant.
They did worse.
And then if you can do that, you can make a claim.
Now, if it doesn't show anything,
it doesn't tell you anything.
What it tells you is either it doesn't work
or you picked the wrong dose.
Right.
And you fucked up and you wasted 20 years.
Right.
You know, and now you've got to start all over again
and decide whether you've got the willpower to.
do it. That's why some of this science moves so slow, you know, and is because of those kinds
of things. It's so difficult to do a study like this and who's going to fund it. So what'll
happen is people will just read this and go, oh, well, hops isn't going to hurt you. So here you go,
maybe this will help. And then you have people like me and, well, you and me taking a bunch of supplements
that we hope will do something for us. Yep. You know, Ray Kurzweil, I don't know if he's
still alive, but he was trying to extend his life until he could upload his brain into a
computer.
And he was taking like 200 supplements because anytime something would come out, at least
this is what I heard, may or may not be true.
Allegedly, you know, if a study came out and said this stuff might help in vitro, in other
words, in the test tube, then he would start taking it as long as it was safe.
So, yeah, my collection is increased.
Now I'm taking phosphatil syrin because of you.
Yeah, so yeah, heck, yeah.
And they all love this stuff.
I think it is.
And nicotinomide riboside and some other things.
And, you know, I don't know.
I look decent for a 67-year-old.
So maybe it's genetics or maybe some of that stuff's helping.
I don't know.
Maybe it's all those hops we've consumed in the last 20 years.
It certainly isn't from all the exercise I'm doing.
That I've got to do something about.
Yeah, I went on a good one today.
I think I told you.
I took the dogs up on the mountain.
Did you?
We did almost five miles.
That's awesome.
And then my cold therapy.
Don't I usually give you the I-Fit thing for Christmas?
Isn't that a Christmas present?
Yes.
Yeah.
So this will be, what, the fourth year?
And we use the fucking thing.
But this year, it will be different.
She's retired this year.
It's the difference.
I got to look and see.
Usually they send me an email saying it's going to expire.
It may have already expired.
I don't know.
Anyway, all right.
That's very interesting, Dr. Scott.
And that's how we would determine that.
Yep.
But I am going to definitely get some hops.
and brew a batch of hoppy,
a hoppy raspberry kombucha
and see what it tastes like.
Cool, cool, cool.
I like it, I like it.
Do you?
I like it.
I'm looking forward to it.
Okay, what else you got?
Do you have anything else?
A couple, yeah, but I've done a couple of questions.
Yeah, I know you sent me a couple of, you want to talk about the bubble.
I'll talk about anything you want.
The combination of ultrasound and nanobbles allows cancerous tumors to be destroyed without any invasive treatment.
Okay, let's talk about that.
So what did they do?
So a new technology they're looking at overseas makes it possible to destroy cancerous tumors in a targeted matter via a combination of ultrasound and the injection of nanobbles into the bloodstream.
Okay.
Whereas before they're actually, when they first started doing this, they were having some luck, actually delivering the bubbles directly into the tumor itself.
That's pretty invasive.
Okay.
And what they found now is they can actually put these microbubbles into the tumor and it –
Oh, and they're forcing it in with ultrasound.
Yeah, and then forcing it in with ultrasound, exactly.
And then what that does is it is actually starting to – the bubbles going into the cancer.
It stars it of its blood supply and starts to lice it, so it starts to kill the tumor.
Interesting.
Yeah, nanobbles are 70 to 120 nanometers in size.
Well, those are really small.
It's 2,500 times smaller.
than a single grain of salt.
They can be formed using any gas and injected into any liquid.
Due to their size, nanobbles exhibit unique properties that improve numerous physical, chemical, and biological processes.
So that's very interesting.
Yeah, so I guess the nanobbles are filled with what?
Oxygen?
I'm looking to say.
Well, that could be air.
I think it's just oxygen, and then they hit it with the ultrasound.
Because you need...
And agitates it.
fluid to pass blood through tissue to make, you know, to grow, and tumors need that too.
And so if you could put nanobbles somehow in there, basically what it does, it robs the tumor of
the ability to get blood supply and it would die.
So, but you've got to get it to the right place and concentrate it there and keep it there.
So maybe that's what the ultrasound is doing.
So did they do these?
What situation was this?
This was in a simulated?
Well, it was in breast tissue of mice.
Okay, okay.
Well, all right.
But, yeah.
So mechanical stuff like this, done in, you know, a murine model.
That's what that's called it when you do it in mice.
Okay.
That's a decent way to start for a human trial because, you know, they metabolize drugs differently than we do.
So something that works in a mouse may not work in a human, but physically.
is the same for mice and, you know, most humans.
So this is a physical process.
The physics is the same.
So this should work.
So that's very interesting.
Yeah, what they're showing is these nanobbles cause by applying the low frequency.
The low frequency to them, it does cause them to swell.
Okay.
And then they explode.
And it's in it.
Oh, that's interesting.
Okay.
See, what they're doing is they're just agitating those.
Then it bubbles to the point where they just lice and they explode.
Yeah.
Okay.
Cool.
Yeah, I'm looking forward to all this kind of stuff.
So that's on breast, which kind of goes to.
We had a question earlier.
Well, the thing is, breast tumors in mice are on the outside of the rib cage.
His breast tissue is, you know, superficial to the rib cage.
Yep, yeah, sure.
So it's easy to get ultrasonic energy into that tissue, whereas if it was colon,
tissue would be much harder to do.
Yes.
So that's why they're using a breast model.
That would be my guess, anyway.
Well, it makes good sense.
Yeah, it would be nice if they could get to some other things like prostates.
Yeah, well, you know, you can get to a damn prostate.
Yeah.
The, you know, the back wall of the prostate is the front wall of the rectum.
Yep.
As many of us are very well aware.
But you think about it, you can actually technically run an ultrasound.
Yeah.
colon.
No, they do it all time.
But then bust those dental bubbles.
Yeah.
Wouldn't that be wild?
It would be a while.
Well, that's cool.
All right.
Yeah, we had a couple good, a good couple medical questions.
Okay, yeah, we probably should do that.
Hang on a second.
Yeah, well, you're...
Number one thing.
Don't take advice from some asshole on the radio.
All right.
Thank you, Ronnie B.
There was one just a minute ago about...
And I'm trying to find it was way back.
About our...
Oh, here we go.
Kidney, kidney cancer.
So, Ryan Kurtz has a question about a, they've got a cancerous gopal-sized tumor in one of his father's kidneys.
Okay.
According to the urologist, has not metastasized.
Okay, good.
Which is a good thing.
They will perform a partial nephrectomy.
Yes.
And looking for some insight.
Okay.
Yeah, so, you know, a partial nephrectomy would be wonderful.
Yeah, so partial meaning they're not going to take out the whole thing.
that part's easy, nephrectomy, nephro relating to the kidney, ectomy, meaning cut out.
So they're going to remove part of the kidney.
Yeah, which would be outstanding.
You know, the thing is with the partial nephrectomy, they go right through the navel,
and you can barely even see the scar.
Really?
Yeah.
I mean, it's a really small incision normally if things go well, obviously.
But the recovery time of that, if it's not metastasized, should be pretty quick.
And as long as he takes his doctor's advice, specifically the nephrologist,
who I'm sure he'll, or I would assume he'll see for follow-ups,
you know, to protect his one kidney moving forward,
which is going to be very important.
Yeah.
So if they do this laparoscopically, then Dr. Scott is correct.
They make two to four incisions in the abdomen, about a half inch or less,
and they get this thin rod that's got a camera on the end,
which is the laparoscope
and they do that into one incision
so that they can see
and then the surgical tools
go into the other incisions
and it's amazing
I've watched this
I don't know how the hell they do it
you just have to
your mindset has to be different
you know now they can do
an open nephrectomy too
so it just depends
you gotta ask
which one are you gonna do
but yeah that's
as long as it hasn't metastasized
and that is
you know the prognosis
pretty good
as long as pop
is in otherwise good physical shape yeah so we please let us know and they can do
robotic partial nephrectomies as well you know if it's small enough they can do it
and it is a robot assisted surgery and the surgeon is in a different room when they do
this it's crazy and and it it is it's nuts yeah
And I've watched that as well, and they don't have to scrub or anything.
You know, they're just sitting over there in this other room manipulating these little Waldo things,
and the surgery is going on in a different room.
It could be in a different town.
It's amazing.
That's incredible.
But it sounds like they must have found it pretty early for them to only have to do a partial nephrectomy,
which is a really good thing.
Yeah, it's major surgery, so you'll have to go through the whole anesthesia and all that stuff.
and the anesthesiologists will make sure that you're fit for surgery and that kind of thing.
And so, you know, but let us know how that goes and give your dad our best.
It was his dad?
Dad, yeah, and tell him just to diet, there's a lot of dietary things you can do to help protect another kidney.
Oh, yeah.
But he should.
Well, it does make the rest of your kidneys a little bit more precious.
Yes.
We have two.
You can live with one.
Fragyly.
Right.
It's very fragile.
Now's going to be there for G.
All right.
He's got a question.
Any benefit from getting MS diagnosed early?
Yeah.
Well, yeah, so he thought he had just had depression, but Webb MD has him convinced he has MS.
Oh, oh.
So that's a little bit of a tricky question.
Yeah.
Because MS can really look like about a thousand different things.
Sure, it can.
It can, it's like, it's like fungal infections can mimic other things very often.
They, particularly on a, if you get fungal infection in your lung, it looks like cancer or something like that.
The other thing is, when you get on the Internet, you've got everything.
Exactly, yeah.
And so, you know, it's a disease that affects the central nervous system.
We have a friend or two that have it.
and, you know, people who have MS may have, you know, numbness or tremors or vision problems.
I know somebody that they would know that the multiple sclerosis was coming because they would have a flare.
Yeah, they would get a flare because they would have, it was like a screen going over their eye.
So it, in multiple sclerosis, the immune system attacks.
this sheath
that it's basically
insulation you know
the wiring in your house
it's got that rubber
coating over it
because if you just had
bare wires
they'd all short out right
cause fires
yeah and cause fires and stuff
and we have
the same sort of thing
this was invented
way before we ever thought
about
transmitting electricity
from one place the other
nature had already done it
it's transmitting
electrical impulses
from one place
to another. It's amazing. And dealing with quantum objects and stuff, the life on Earth is an
amazing thing. But anyway, this protective sheath is called myelin, and it covers the nerve fibers.
And what happens is when you attack it, you get interruptions in it, and it causes communication
problems between the brain and the rest of your body. And there's a lot of, a couple of, you know,
several different kinds of multiple sclerosis.
And one is the, you know, chronic remitting where they have attacks,
and then they're okay in between time.
And then there are other people to get this sort of chronic progressive disease
where they just get worse and worse and worse.
Primary progressive, yeah.
So, you know, when you have numbness or weakness in one or more limbs,
and it typically occurs on one side of the body at a time,
that might be suggestive of it.
These sort of shocking sensations that occur with certain neck movements,
but that could be lots of different things.
Tremors, unsteady gait,
which is why this is difficult to diagnose
because there's lots of things that can cause tremors
and unsteady gait, loss of vision,
maybe double vision.
Other things can cause that, too.
We've got a good friend of this show
that had double vision.
He didn't have MS.
He had Graves disease alluded to it,
so I'm not saying anything that he wouldn't say.
And Graves disease is a disease of the eyeballs that is caused by thyroid disease.
It causes your eyeballs to bloop out, and now they don't work perfectly anymore.
They don't track anymore.
You can get slurred speech, fatigue, dizziness, that kind of stuff.
So most people have this sort of remitting, relapsing course, where it comes and goes.
But, again, as we said, there are people that have primary progressive.
Right.
Now, we usually, there's several ways you can diagnose this.
One of the things that they would do, if they really thought that you had it, would be to get an MRI.
And the MRI, you can see the changes in the myelin she thing.
And it's pretty diagnostic.
But anyway, you got anything on it?
Yeah, just go get it.
If you think you have, yes, I guess his question is, I looked at the Internet and I think I have this.
should I go or should I wait?
If it's wearing on your mind, you wake up in the middle of the night.
Our son, you remember Beck used to think he had rabies?
You remember that?
And then he would wake up and say,
Dad, can you get rabies from licking the peanut butter jar or something?
Which told me he'd been licking the peanut butter jar.
It's like, no, dude, you can't.
You go, okay, and he'd go back to bed.
But it would wear on his mind for a while.
That went on for a little while.
This can wear on your mind and bug you,
and it can mess up your lifestyle
and your memory starts to go
because you have these intrusive thoughts
about having multiple scleros
like, we get checked out, you know?
Definitely.
Do it at your next primary care visit
if you can wait that long
if you can't make an appointment.
Yeah, certainly, yeah, it's a really tough thing to treat.
The relapsing remitting sometimes a little bit easier
taking away some of these.
It's gotten a lot easier.
We used to have no treatment other than steroids.
And back in the day,
but now they've got these biologicals
stuff and really they've gotten so much better. Plasmix change. You can do plasma
phreasis, just cleanse your body of the offending antibodies. Yeah, I've even seen
do a bone marrow transfer, where they radiate all the, kill all the bone marrow and put
really? Yeah, yeah, yeah, yeah. But that's the extreme version. Wow, I've not, I have not
heard of that, but I'm not an expert on this. No, no, no. They do interferons. There are monoclon
antibodies that can you know modify the disease so you know all kinds of stuff and a neurologist
typically are the ones that treat this and you know it is it is way way way more treatable now than it
was and i'm looking and scott i believe you but i'm looking at Mayo Clinic i don't see anything
about bone marrow replacement on that yeah it was actually um i'm not saying it yeah that it isn't
but that's that's outside my experience so but
Anyway, Amy was saying that Nano Bubbles was her stripper name until she grew boobbles.
Nano Bubbles.
It's another person I can think of that isn't here today.
Oh, I love it.
I love it.
I love it.
I love it.
All right.
You got anything else from the waiting room?
We've got a couple other regular calls.
Yeah, somebody else had one.
I think Bobbubbibing had one.
Okay.
Let's see.
Okay.
medical questions. Since yesterday evening, I have this itch on my wrist, wrists, both wrists,
my neck, some of my fingers, some of my chest, as if there's something, some kind of allergic
reaction. There's no rash or any other visible signs. No other symptoms. No bug bites that would
have caused it. What should I do just take some Claritin or something similar? He doesn't
usually have allergies. Yeah. Okay. Ask him if he's a big time drink.
Big-time drinker, smoker, what changes medications or anything like that?
Yeah, any of those things, you know, I'm being somewhat ridiculous, he would know, cirrhosis can certainly cause itching all over.
There are lots of things that can cause itching all over, but if it's, if it comes and goes, see, that's the thing.
Cirrhosis and those other really dangerous things don't come and go.
they come and stay.
So it's more likely that he got into some weird detergent.
If it's only in places where his clothes touch, then it's most likely a return.
Yeah, wrist, nature.
That's what I was thinking, too.
It's more likely something like that.
Yes, you can just take something.
If it goes away, forget about it.
If it doesn't go away, then, yeah, I get it checked.
Clareton, Benadryl, something like that.
Yeah, yeah.
Yeah, I think it's raised over-the-counter stuff.
It's totally fine.
It's hard to...
No drinking, no smoking.
Okay, good deal.
It's hard to bathe your whole body in cortisone,
so it's easier to take a non-drowsy antihistamine
like fexophenidine, aka A. Allegra or something like that.
All right.
Yep.
All right.
Anything else?
Okay, let's do this one.
I think we're good, yep.
Uh-oh.
Hey, Dr. Steve and Dr. Scott.
Hey.
Hey.
I'm a 26-year-old guy, and so sometimes when I'm laying in bed at night,
you know, jerkin the gurkin.
Excellent.
And after I, you know, bust the nut.
All these euphemisms, jerking the gurkin and busting and thund.
I'll get this sensation like I really have to, like, take a kiss.
Yeah.
Or I'll doze off.
And after 20 minutes, half hour.
Yes.
I'll, like, get up with this sudden urge.
Yeah, I know what this is already.
Now, sometimes I go piss, and then it just gets worse.
Yes.
In any case, I have to sit on the toilet and, you know, just letting out dribbles of piss
for intermittently for, you know, a half hour, 45 minutes.
Yeah.
And just keep doing that until this sensation subside.
Yeah.
Now, I've tried Googling this and you need to listen to our.
show more because we've talked about this
where I know exactly what this is and I
can get you off the toilet
the question I have is when he's
jerking his gurkin in bed
what's he do with the
you know with the
product fluid to just go
on his stomach and then he squeegees it down
with his underwear well there is
disgusting there is a comedian
out there that that's their closing
jokes no everything on Google
just says oh you got a UTI
or, oh, you got an STD.
Wrong.
Now, I don't have.
Okay, this goes on.
I am interested to see what else.
I have any burning when I'm pissing during the day.
Right.
I've, you know, been tested regularly for STDs, and I'm always negative.
Yep.
And I just have no idea what this is.
And it has.
Okay, he keeps going.
I am very curious, but we are kind of running out of time.
I'm very curious to see what he has to say.
I know what this is.
This is a spasm of the ureed.
Reprethal spasms.
I should have just asked you.
That was one I should ask you.
Here, Scott, do you know what this is?
It's a urethral spasm, of course.
Give yourself a bill!
Yes, a bill finally before the time runs out.
I never get those.
Yes, you do.
You get one every day.
Don't want one.
Give yourself a bill?
Give you one any.
It's not fair.
Give you one anyway.
Here's another one.
Give yourself a bill.
That's not fair.
It was funny when I gave Anthony a couple of those when he was on our podcast, or on the
Patreon show. Check us out at patreon.com slash weird medicine, by the way.
We recently had Pete Davidson on there. That was a great show. Got him for all of 10 minutes.
10 minutes. And we've had Anthony Coomia, Bobby Kelly, Joe DeRosa, Mark Norman, and some
other folks like that. So, um, we had Greg Opie Hughes. We've had Jim Norton.
This is urethral spasm. Other people have this. Let me tell you what to do. When this
happens. And I
you know how I know this? Because
from experience. You've experienced
this. Yes. Take
a glass or
something, a cup, and
put warm, not a hot water.
Thimble. Yeah, a thimble.
You're hilarious.
And then you're going to...
Give him a bill.
I need another bill. Okay, yeah. Yes,
it's Thanksgiving. Thank you, thanks.
Okay, let's see.
You are a liar, actress.
Go the f*** out.
You, um,
dip your penis into this warm water.
Now, it needs to be warm enough.
It needs to be slightly warmer than body temperature.
Is this happen to our glasses and our house?
You're the one that you drink out of?
Yeah, yeah.
I clean it out afterward.
Don't worry about it.
Oh, good. Great.
I'm, you know, obviously, I'm kidding.
But you dip your penis in this warm water and this sensation will immediately go away.
Now, if it doesn't, it's not warm enough, but don't make it so hot that you injure yourself.
It cannot be hot.
I don't want to hear about somebody.
I'm telling you not too hot.
It needs to be just above body temperature.
And so test it before you put your junk in it.
So Amy says dunk your junk.
That'd be a good band name for us.
Be a good t-shirt.
Dunk your junk.
Good t-shirt with a penis going into a glass of,
warm water, and no one would understand why you had this horrible image.
But yeah, that normally will take care of it, and you'll be right back to bed and
you can clean up whatever mess you made otherwise.
All right.
All right.
Well, let's get out of here.
Thanks, always go to Dr. Scott.
Thanks, Tacey.
You're welcome.
Didn't hear too much from you today.
That's okay.
I was drinking.
Next time.
Oh, you are drinking?
Yeah, a little bit.
Oh, okay. Am I going to have any fun today?
No, no, you're going to be cooking.
No. Man, you are one pathetic loser.
Thanks to everyone who's made the show happen over the years.
Listen to our Sirius XM show on the Faction Talk channel.
Siris XM, Channel 103, Saturdays at 7 p.m. Eastern, Sunday at 6 or 10 p.m. Eastern on demand, the best way.
And other times, it's Jim McClure's pleasure.
Many thanks to our listeners whose voicemail and topic.
make this job very easy go to our website at dr steve.com for schedules podcasts of the crap
until next time check your stupid nuts for lumps quit smoking get off your asses get some
exercise we'll see you in one week for the next edition of weird medicine thanks
everybody thank you goodbye
We're going to be.