Weird Medicine: The Podcast - 551 - Drinking is Bad, M'Kay?

Episode Date: May 17, 2023

Dr Scott is on sabbatical and Carissa and Tacie decide it'd be a fun time to drink. Of course they're served with a PWI ("podcasting while impaired" HAW HAW yeccch). Topics include: Organ donation ramp salt incidental coronary calcium findings tetanus destroying your eardrum with high pressure lavage weed vs alcohol vaping vs the world Please visit: stuff.doctorsteve.com (for all your online shopping needs!) ed.doctorsteve.com (for your discount on the Phoenix device for erectile dysfunction) simplyherbals.net/cbd-sinus-rinse (the best he's ever made. Seriously.) roadie.doctorsteve.com (the greatest gift for a guitarist or bassist! The robotic tuner!) Also don't forget: Cameo.com/weirdmedicine (Book your old pal right now while he’s still cheap! "FLUID!" Most importantly! CHECK US OUT ON PATREON!  ALL NEW CONTENT! Robert Kelly, Mark Normand, the O&A Troika, Joe DeRosa, Pete Davidson, Geno Bisconte. Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices

What's brown and sounds like a bell? Dong. Why did the farmer trade cow manure for goat poop? It was a dung deal. Did you hear about the dirty Easter egg hunt? It was hosted by the Dust Bunny. If you just read the bio for Dr. Steve, host of Weird Medicine on Sirius XM103,

and made popular by two really comedy shows, Opie and Anthony and Ron and Fez, you would have thought that this guy was a bit of, you know, a clown. Why can't you give me the respect that I'm entitled to? I've got the theory of crushing myself. I've got Tobolovir, stripping from my nose. I've got the leprosy of the heartbound, exacerbating my infectable woes.

I want to take my brain out and blast it with the wave, an ultrasonic, egographic and a pulsating shave. I want a magic pill. All my ailments, the health equivalent of citizen cane. And if I don't get it now in the tablet, I think I'm doomed, then I'll have to go insane. I want a requiem for my disease, so I'm paging Dr. Steve.

Dr. Steve. From the world famous Cardiff Electric Network Studios, it's weird medicine, the first and still only uncensored medical show in the history of broadcast radio, now a podcast. I'm Dr. Steve with my little pal, Tacey. Hello. Hello, Tacey, and my partner, Carissa, D&P, Carissa, hello. Hello. This is a show for people who would never listen to a medical show on the radio or the internet.

If you've got a question, you're embarrassed to take your regular medical provider. If you can't find an answer anywhere else, Give us a call at 347-76-6-4-3-23. That's 347. Pooh-Head. Follow us on Twitter at Weird Medicine. Visit our website at Dr.steve.com for podcasts, medical news and stuff to come by. Most importantly, we are not your medical providers.

Take everything here with a grain of salt. Don't act on anything you hear on this show without talking about it over with your healthcare provider. Okay, please don't forget to check out stuff.com.com. Stuff.doct.com. interested in the phoenix erectile dysfunction device this is a an acoustic shockwave device that you can pay thousands of dollars to go to a med spa and have a stranger you know cradle your jungle region while you scream it's the shrinkage the shrinkage while they're running a probe up and down or you can buy this thing uh and do it yourself in the privacy of your own home for

a fraction of the cost i'm not saying it's cheap It is expensive. Go check it out, though, at ed. Dottersteve.com. And if it's something that you think you need, talk it over with your health care provider, but they have a payment program, too. You could do $29 a month.

Is it cheaper to do it? Oh, way cheaper to do it at home. Yeah, it's a fraction of the cost, what you would pay at a med spa. And then you have it. And then you have it, right. And you can do maintenance with it, and you don't have to keep going back and going well, you know.

Yeah. So anyway, check that out. ED, as in, you know, E-DELTA, dot Dr. Steve.com. And check out Dr. Scott's website at simply Herbal's.net. And go to patreon.com slash weird medicine.

We need to do a Patreon show, ASAP. ASAP. And Patreon.com slash weird medicine. Tasey and I do a show there. It's different than this show. It's all new content. And sometimes we interview celebrities or we have them interview us. Basically, they come on

to ask medical questions. So they won't wake me up at two in the morning, asking me the same dumb questions. Oh, Lord, but there's been a lot of drama lately. Oh, yes, okay. So without saying anything more than that, but yes, that is true. There has been a lot of drama lately. I think it continually. You think that's?

I think that's just how it is. Yeah. Drama. And then cameo.com slash weird medicine. Camio.com slash weird medicine. I'll say fluid to your mama or I'll say anything you want me to say to her within reason, of course. And now. He's nice to your mom.

Tacey and Carissa have been drinking, so this will be an interesting show, so I'm looking forward to it. Liz, let's get going. You ready? Sure. Check out Dr. Scott's website. It's simply herbals.

Nat, that's simplyerbils.net. He's not here, but he's still... He feels empty without him. It does sound empty without it. Yeah, I don't like... Now, last week, we did nothing but questions, and we still didn't get to half of the questions. But I don't think that we should continue,

and I'm sorry that was so loud, with questions when Scott is not here. Really? Why? Well, what should we do? I mean, I don't think we should do a whole show of just, yeah, let's, a guy walks in a bar. Let's just do a normal show and get to the questions that we can, listen to me be a boss. Really? This is hilarious. So. That's what you always do.

Yeah, I'm sorry. And so let's just do the show with our little segmenties. Is that a new word? And then when Scott's here, we'll just do another question show because he's got a lot of answers. Okay, well, it sounds good to me. Let's do the first segmenty. Ain't God.

It's Tacey's Time of Topics. A time for Tacey to discuss topics of the day. Not to be confused with Topic Time with Harrison Young, which is copyrighted by Harrison Young and Area 58 Public Access. And now here's Tacey. Well, hello, everyone. Oh, God. Hello.

Okay, so... Have you guys been drinking down there while I was doing my talk? A little bit. Yes. Okay, okay, that explains. So, this story came from Scott... Well, that's because you're an idiot. No.

It's because I like to have fun. Okay, go ahead. Okay, so this story came from Scott, which is why it's so boring. Oh, my God. Yes. And he's not even here. I know I wish he was, though. Oh.

Okay. More than half a million UTIs are linked to contaminated meat in U.S. each year. I'm sure your boyfriend will be back next time. It's fine. Half million UTIs in U.S. may be caused by e-coli strains from meat products. What? Wait, whoa.

Urinary tract infections? Yes. From eating meat? Yes. Well, what's the mechanism of that? Well, I don't know. They have to read on and see what happens. They slapping the meat on their jungle regions.

They're using a neogenomic approach to track origins of E. coli infections. At George Washington University, they established that 480,000 to 640,000 UTIs, according to analysis, published in the journal One Health. Hmm. You okay? Are you dying? Yeah, it's fine. Do not resuscitate me. She's got the consumption, don't you know?

Apparently, lots of studies show when people have a bladder infection, it's caused by the same e-cola they have in their gut. Well, yeah. But how does it get into our guts? Because they wipe the wrong way. Oh, how does it get into the gut? Okay, sorry. Here's what we know.

A UTI can affect any part of the urinary system and are treated with antibiotics. Here we go with the writing And these, I do these sober So this is not Are you ever sober? Yes When she wakes up So, okay

So yes A urinary tract infection can be anywhere in the urinary tract From the kidney Through the tubes going from the kidney To the bladder Which are called the ureters To the bladder to the urethra It's a little bit of background information

That's right Yes, yes Women are at a greater risk Yes. Why? Why? Well, it doesn't say. UTS can be laugh-threatening when severe. It was a rhetorical question. I'm going to answer it. Because there's less distance between, there's less protection between the outside world and the inside world for women because your urethras are shorter. The male urethra is, well, you know, in my case, like, you know, eight and a half inches from the outside from the bladder. That's what I was going to say. I was going to give you 11. Thank you. Thank you. The female urethra is much, much shorter than that most of the time. And when I'm talking about, you know, when we're talking male and female, we're talking about sex and assigned sex. So if you don't have a penis, your urethra is shorter. And it's just the penis. The penile urethra is longer in man than it is in women.

there's more barriers to bacteria getting from the outside to the inside. And that's why. So anyway, go ahead. Okay, so the annual National Emergency Department Bill for Complex UTIs rose from $2.8 billion in 2016 to $3.2.28. God, that's crazy, isn't it? There's so many urinary tract infections that include the doctor visits, the prescriptions for Bactrum, and, you know, fluoroquinolones and other drugs like that

that cost billions of dollars a year. That's insane. I mean, I guess that's crazy. Well, it's so common. But anyway, go ahead. I mean, I have friends who have them all the time. And maybe we should talk about why people get them all the time. I know that you're supposed to pee after sex, and that helps.

But I know someone who gets them. Consistently, and she... What? Go ahead. You want to... And she does get them all the time. So, okay, scientists isolated, e-coli strains collected from raw chicken, turkey, and pork. Yes. And then compare it with urine and blood samples from patients.

So people aren't washing their hands after handling raw meat? Maybe so. And they found about 8% of e-cola urinary tract infections could be linked to meat. That's disgusting. Okay. So I can see. a way this would happen, though, is you eat the meat, right? I mean, that's what you're supposed to do with it.

And some of the E. coli survive, get into your colon, and then they can detect the DNA in your stool and in the bladder, but also on the surface of the chicken or poultry or whatever. So this could just be as simple as people wiping from back to front instead of from front to back, right? And then they're getting urinary tract infections because those E. coli are in their rectum. Never mind. And they are getting into the bladder through that loop.

And so it would make total sense. Maybe I mean, if there's E. coli on your food, it's going to end up in your stool at some point. The stomach, particularly in the United States. where people are taking proton pump inhibitors and H2 blockers to increase the pH of their stomach and more bacteria will make it through from the upper GI tract to the lower GI tract. Do you think that that's a viable hypothesis?

I do believe so. Scientists isolated e-coloss strains collected from raw chicken, turkey, and pork, then compare it with urine and blood samples from patients. Oh, I already read that. strains of E. coli are not seriously monitored in U.S. food supply, no regulations as to how much can be on the meat, which is interesting. Right. So it is allowed to pass through the food system because it's not deemed to be a risk. Hmm. Hope is that their findings will encourage federal regulators to monitor other types of possible

harmful strains like salmonella potentially to try this approach with other types of pathogens. My understanding is that all chicken, and if anybody raises chicken or cells processed chicken, that all chicken in the United States has salmonella on it. That's just how it is.

That's why you don't eat raw chicken. So it has to be cooked properly, either in sousvied, up to 130, 135 degrees and kept there for 90 minutes or to you know if you're going to do it in the oven it's got to be brought up to 165 degrees

and that kills the bacteria that are and chicken is more porous than beef that's why you can eat raw beef but you really can't eat raw chicken Is this a cooking show? Yeah well chicken tartar is not a thing but beef tartar is

so they I don't know what they're going to do about this And if you say, well, you must do something about it, then they're just going to throw more antibiotics. This came from one of Scott's hipping. No, it's fine. I mean, I'm just saying they're going to throw more antibiotics at these animals and I think make antibiotic resistance that much worse. I think we just have to live with the fact that there's bacteria on our food and we need to cook it properly so that we don't cause problems for ourselves. And clean your hands.

And then you cut the meat on. Yeah. Right. And don't wash your chicken. If you learn nothing else from this show going forward, do not wash your chicken in the sink. Because studies have shown that when you use the sprayer to wash your chicken off, that what it does is it spray salmonella all over your house. And then you can get it through fomite transmission where you touch something where one of those droplets went.

You stick it in your mouth or your nose or your eyes and now you've got a problem. so okay so that is topic one okay excellent wow very good well we'll give you a bell for that one here give thyself a bell we'll suck it chrisa oh well i might so topic number two is about misophonia oh oh misophonium yes we can all relate to the feeling of repulsion when hearing someone's scrape their nails down a chalkwork, but some people can be triggered by far less, which is totally true.

You know, P.A. Lydia can be triggered by a picture of an object that's got holes drilled in it. And she'll look at it and she'll go, and she'll start gagging. So this will be interesting. I miss her.

It's called mesophonia. Wait. UK survey suggests it's common. Chewing, slurping, snoring, and breathing. It's more than being annoyed. It's about feeling trapped or helpless because you can't get away from the noise. You're sitting in an airplane. Yes. Next to some stranger and they brought a fucking subway disgusting smelling sub with oil and vinegar and onions and stuff. I know it sounds good. And then they're just chomping away and you can hear

the sound of them eating. Close your fucking mouth. Yes. Thank you. I guess I have mesophonium, too. So I was trying to give this guy credit here, so just bear with me. Okay. King's College London psychometrician Celia Viterator got volunteers

of all-sex agent ethnicity to get a representation sample of 18 years and older. He had 772 volunteers, did a question questionnaire about triggers, sounds, and emotional responses. Okay. He probed five aspects of misophonia.

Mm-hmm. Emotional threat, internal and external appraisals, outbursts, and impact, and then it goes to... Prevalence is 18.4%. Hmm. Loud chewing triggered most disgust. Yes, it's disgusting. No one wants to hear you chewing. Mm-mm.

Key differences between... misophonia and general population anger panic trapped an ability to escape guilt shame anxiety because it's your wife and she's sitting next to you sometimes or your husband no i don't mean you one in five in uk have it which i thought was pretty interesting but only a few are aware so people are like just really annoyed a lot of times but not aware of exactly why yeah they blame it on the person and maybe not the noise like that effing whore sitting next to me. Stop it.

Further research is needed, and this research was published in P-L-O-S-O-N-E. Have you ever heard of that magazine? What is it, plus one? Yes. P-L-O-S-1? Yeah. Yeah, plus one. It's a online thing.

This is supposed to be eating sounds. It's not really... Oh, there we go. There you go. This is a person eating a cheeseburger. It sounds like a pig. I'd rather hear a pig eating. That's at least cute.

Why is it weird? Oh, okay. Why is it okay? Anyone with mesophonium just turn their radio off? One in five, baby. Why is it cute to hear a dog munching down on stuff, but to hear a human doing it is disgusting. Because a human should have simple manners.

Okay, that's true. A dog is not taught manners. Doggies are good. Tell me I'm wrong. Does anyone grow up being taught to chew with their fucking mouth open like a horse? No, that's true. You know, our son... We do have lips.

Close them. I always say, say yes and say no. And we go in there and it's like, yeah, nah. And it's like, I taught you... Are you feeling any better? No. No. See, I always told you, yes, ma'am.

No, ma'am, yes, sir, no, sir. And that's offensive now. I think ma'am is offensive. I'm like, I prefer to be called Hot Young Thing than Mayam. Yes, hot young thing. No, thank you.

Oh, well, that is very interesting. Please tell me more. All right, so that is it. What topic time today? Oh, very good. Well, thank you. It's Tacey's Time of Topics. All right, thanks.

Thank you, Scott, for your information. Very good. All right. So, let's see here. Boy, I am, I gave a talk just before this, and I'm a little discombobulated myself. How about you want to do some questions? Let's do them.

Number one thing. Don't take advice from some asshole on the radio. All right, very good. And here we go. This is a good one. We need to get this one. Hey, Dr. Steve, it's Stephen. Your friend from Texas with the liver and kidney transplant.

I just wanted to. Hey, Stephen. If you could remind the listeners that today, this month, is actually donor awareness month. Being a donor saves life, I'm living proof. I wanted also tell you how much I appreciate you helping me a number of years ago when I first started having these problems and you kept up with me and checking you on me. And I give you credit for help saving my life. Oh, wow. I really appreciate you.

That's wonderful. I look forward to talking to you personally, hopefully, one day, and maybe sharing with your listeners about this whole process. It was long, hard. It was very long and hard. Yeah. I'm very lucky to be here. Very lucky to be here. And I owe some of it to you.

Thank you so much for your kindness and understanding. Oh, heck, heck, ma. And I hope to be able to talk to the listeners here soon. Yes, I would love that, Steve. I think that's great. You know, my father had a kidney transplant. He did. It extended his life.

And he lived by about 10 years after. Yep. And he didn't have to have dialysis. So that was a big deal. No, he never had to have, which, yeah, is, it seems a little unfair with people who do have to versus people who don't. I don't know if some people are explained to me that because some people do have to have dialysis as they're waiting on a kidney.

transplant and then others just oh my kidneys are bad and then they get one before you know it and it just it does seem well there are certain criteria for they they want to know that you're going to live long enough to be able to use the donor kidney and the problem is that there are so few uh kidneys or organs out there and then finding a proper match and then taking the anti-rejection drugs and then you've got to find a center that is willing to do it. You can't just go to any old place, any community hospital, and get a organ transplant. So what we really need is the ability to grow these things in a petri dish from your own cells, and then you don't have to worry about rejection.

You don't have to worry about a donor, and that will become a lot more plentiful, and they'll have fewer criteria. For example, you have to be sober. You can't be on certain drugs. You can't be taking pain medication for a lot of transplants. Liver transplant, very difficult to get. If you're taking any sort of pain medication or you can't drink, you know, they're just a lot. And a lot of people who need a liver transplant are people who got that way because they were drinking.

And it's sometimes hard for them to quit. and they just never get to the point where they're able to take the transplant. So it's a big problem. And until we have new technology, either mechanical kidneys that really work that will last year your whole life and you can just put them in

and somehow perform the function of the kidney, which is to resorb electrolytes and excrete waste in, you know, water-soluble waste, and to maintain blood pressure, the kidneys do all kinds of stuff. So you can't just have a single-function machine that you put in. It has to have multifunctional state. And so very, but until then, we have to donate our organs. So you can sign up to be an organ donor.

Just go to organ donor.gov. You select your state and it'll walk you through the process. And you won't care when it comes to. No. And exactly right. Very good. You know what? You get to get another. Give myself a bill. Somebody really sucks today. Just because... I always suck. Just because it's important to realize that your demise can actually do somebody some good. That's one way to think about it. It's the silver lining.

I just went down a rabbit hole. So sorry. That's where I went. A donation? And what did you find out? Like using cells to create organs and also injecting cells. There's a trial that was done as far as injecting cells into someone else's body. Okay. Into the donor's body and creating another organ within their body. Oh.

Wow. Read us that. That's worthy of stopping this. I mean. I'm literally just like the first sentence in. So I'll research it more, but literally it's just... Okay, well, it's a teaser for five minutes from now, right? I really think we should have...

You're going to read up on it and then tell us about it here in a minute when I finish my spiel about being an organ donor. I just want to say, I really think we should have someone who has had a transplant on the show. Yeah, I agree. I agree. Well, we can do that. We can make a difference. I have his number. Yes, I would love to have him on it. And this is specifically talking about livers. That's okay. because livers are so hard to get.

All right. Well, what's you got? Nothing. I'm still ready. Okay. Well, keep giving us updates on your progress. You can grow many livers. Jesus' crap.

So. In pigs. Or mice. So they, yeah, just sign up and be an organ owner. You can put it on your driver's license. Let all your friends and family know. And to be an organ donor for the, Those kind of organs, you either have to be imminently getting ready to die, or you need to be brain dead, but still be on life support.

So your heart is beating. Oxygen is going in, but no oxygen is being pumped to your brain. And then they can take you into the operating room, and they can get your liver, and they can get your kidneys and your heart, and they can take your lungs that somebody has a heart-lung transplant that they need. And it really can completely turn somebody's life around. And they don't just put these organs in people on a whim. It's always people who will not make it very long if they don't have a transplant. And some people go on to live normal lives for quite some time. So it's really worth doing.

And it doesn't cost you anything. As a matter of fact, if you don't have viable organs, you can donate your body to a place like Restore Life USA. We've got one of those places in Elizabeth in Tennessee that's not too, too far from the weird medicine studios, where they'll take your body after you're done using it, obviously, and they do medical research, and then they cremate you and give you back to the family within a month free of charge. You get a free cremation out of it, and you get to advance medical science. So there's a lot of stuff you can do with your body after you're done using it. But, yeah, if you guys want to do a segment and have him in.

I would love to. We'll do that. I really would love to. All right. We'll do it. All right. DMP, Chris, you got anything on that implantable liver? I mean, I'm still reading the study, but there is, I'm reading about how they studied it in pigs.

Yes. And for example, they surgically diverted the blood supply away from the liver in the pigs to cause liver damage. Sure. And then once they had recovered from surgery, the team injected healthy liver cells into their lymphs. into their lymph nodes. And within a couple of months, the animals appear to show recovery from their liver damage.

Get the hell out of here. That's pretty interesting. Yeah, because, I mean, the lymph node system. Yeah. Yeah, we have to have things like this because the donor program's amazing, but again, how many people are actually brain dead on the vent? You know, a lot of people die

and then they can't use the major organs by the time they get there. so we need a way to manufacture these things or maybe not yours but maybe we can grow in vats all the kidneys and livers and hearts and stuff that we want that have no markers on them they just don't have immune markers on them

the body won't kill those so that would work too so anyway any of those kinds of things there are some organs that we can replace with machines Who said that? Yes, very good. Okay, very good. That's what I was exactly.

The heart is purely a mechanical device. It's very complex and has some really cool electronics and stuff in it, but it is a mechanical device that can be replaced by a mechanical device. You know, lumbar discs and intervertebral discs can be replaced by synthetic things because they're just mechanical objects, you know. But things like the pancreas is, that's one that's a little more complex, but relatively easy to replace with machines. You just have to, if you're just going to do it for insulin,

you have a probe that hears the signal of blood sugar, and then another device that injects the right amount of insulin when it receives that signal, that'll take care of that. Then you can just take pancreatic enzymes by mouth and replace the other part of what the pancreas does. Now when you get to things like the liver and kidneys is way harder, the liver is an unbelievably complex chemical factory that takes molecules and just changes them from one to the other

and makes bile, and it does so many things that's interconnected with a lot of different systems in the body. the kidneys are also difficult to replace. So, you know, those are the things where we've got a lot of room to improve on medical science on those. Anyway, all right, very good. Very good. Yep. Hey, Dr. Steve.

Hey. This is Dan. Hey, Dan. Ramp salt. Oh, it's old Ramp Salt. Go to West Virginia, or just Google West Virginia ramp salt. And he, do you know what guys know what ramps are? A lot of people think they're delicious.

They are delicious. You can just pull them right out of the ground and eat them. Yep. and he makes he dries them and mixes them with like kosher salt or you know and sells it as ramp salt it's i think it's so good google if you don't mind w v rampsalt.com i think that's the one where he is anyway all right i just had a lung screen done and it said my heart was good my lungs were good but i have severe coronary calcification don't uh-oh and i was wondering If you could talk about that and let me know that there was an alternative to having any kind of surgery or...

Well, okay, yeah, let's not put the cart before the horse. You're not symptomatic, but you want to prevent heart attack and stroke. So if it was truly read as severe, I would see a cardiologist for this and say, hey, I had this scan. It showed severe calcification. I know that's not the scan. where we're actually looking for heart stuff. So this is what they call an incidental finding. But the incidental finding is something that we don't want to ignore.

And they will do some tests on you and try to mitigate your risk. Number one, don't smoke. If you're diabetic, get your sugar under control. If you have high blood pressure, get that under control. And, you know, increase your exercise. But see a cardiologist and let them look at it and see if they want to do some other testing. They may throw you on a treadmill, or they may, even if it looks bad enough, they may want to do a cardiac cath, yeah, and just see how obstructed you are. Because

you can have calcification, not be obstructed. You can also not have calcification and be completely obstructed. So that test is not a great test for cardiac risk, but it is a test that says, hey, there's a, we got a signal here. Maybe we need to follow up on it. Okay. Did you find the website? Was it WV. Yeah, it looks great.

The website looks fabulous. Yeah, we need to get some of that. And you know. I've never heard of it before, but it's WVRampsalt.com. Yeah, and I did, I dry brined this year for Easter. I dry brined a rib roast. And it was, we used sand. the cooking guy's BFF to dry-brien it.

A little plug for him. Go to ST. Sam the cooking guy. S-T-C-G.com. Oh, shit. How old that? And his salt and pepper and spice mix called BFF. And best effing flavor or something like that.

But it's really, really good. And I dry-brined it with that 24 hours in the refrigerator, uncovered. and then baked, roasted it at 250 until the internal temperature was 120, took it out, let it rest for an hour. The internal temperature continued to rise as it equilibrated up to about 150, 140, 150. And then threw it in the oven at 500 just to crisp up the outside. It's perfect. That's perfect rib roast. But anyway, I would like to try the ramp salt as a dry brine and see how it does.

He's at the cooking guy.com. The cooking guy.com, okay. And I think that would make a really unique tasting roast, and we should try that. All right, so there you go, my friend. Good luck. Yeah, good luck for that. Hey, Dr. Steve. I've got another question for you.

Okay. It's hard to kind of explain. So white blood cells and sperm cells are kind of like autonomous. but how do they have energy to be mobile and all that stuff and how else are any other structures or parts of our body that are kind of completely autonomous from us and not connected to us just curious thanks right oh this is an interesting question now DNP Carissa do you want to talk about how cells have energy to do things in the body do I want to

Yes. No. No. Cells, you know, create ATP and just make energy. Okay. Wow. That's a... It was a really good description, wasn't it?

Yes. Well, ATP is the sort of powerhouse of the cell. The mitochondria helped to also power cells. but ATP is that is sort of the gasoline of the cells but there are other high energy compounds that are used for biological work but sperm cells for example are produced in the human testes and then they are released as semi or they're autonomous with one purpose to fertilize an egg

and just you know half the time they get spewed out onto a Kleenex or something I guess and they're like, well, you know, what the hell? But the rest of the time, we forget that their job is to, you know, invade a uterus and then look around for an egg that wants to be implanted. And, you know, the odds are just unbelievable. Unbelievable. It's amazing anybody ever has kids. It's true.

250 million sperm and one egg, and one of them's got to impregnate this egg. and then it's got to go through all these processes to produce a human from that one fused cell. It's unbelievable. And just think you're the sperm that won, right? Exactly, right. It's crazy. Yeah, it is nuts.

So they power their movement through stored, when they're created in the body, they have stored carbohydrates that then are converted to this ATP. which then allows them to move their tails, basically. And if you want to see something amazing, just look at sperm cell tail motility, and there are these 3D recreations of what the molecules are doing in there, and it's just motors. I mean, evolution created motors before people even thought that there was such a thing like a wheel

or anything like that. It's unbelievable. So the bioanergetics of sperm our cells are very, you know, it's very complicated. But they, you know, glucose is oxidized to this pyruvate and then you get this 2 ATP and you get an electron in the form of this stuff called NADH. And then you owe you, it just goes on and on. But just suffice it to say that there are. mechanisms, chemical mechanisms that allow energy to be transferred from energy to motion through these bio-energetic

pathways. And the same thing with white blood cells. But we think of them of being separate from us. They're not. We think of ourselves as being separate from the universe that we are born into, right? because we think of ourselves as being autonomous sacks of meat that are separated from the ground because I can lift my feet up from the ground. But we are not dumped into this world.

We are born into this world. We start as a one cell and every atom in our body was created in the heart of a star. So we are not separate from the universe. we are born into the universe. We're born out of the universe and we're inherently part of the universe. The same way that white blood cells are not separate from us, they are created in our body and then release to do their thing.

And they're inherently part of our body. And they won't live any amount of time outside of the body, just like sperm cells won't either because they just get dry and crusty and all nasty and you've got to clean them up the next morning. But anyway, so... The next morning. What are you talking about?

I don't even know. Oh, stop it. So, anyway, all right. So, yes, it is fascinating. And the whole idea of bioenergetics is incredibly complicated, but also just amazing, that this shit was going on. You know, we talk about how proton pump inhibitors. like omeprosol, aka prilosec, block a pump in the stomach

that moves a proton from one side of a membrane to the other. Acid man. Protons. That's what we called it, acid man. Protons are quantum objects made up of three quarks that are bound together. They get almost all of their mass from the binding energy

of those quirks just interacting with each other. And yet, so they're a quantum object, and yet dinosaurs had proton pumps in their stomachs. And they were manipulating quantum objects before humans even were part of this world and we only conceived of quantum objects 100 years ago. It's fucking unbelievable.

Yeah, it really is. Okay, but it's enough. All right. I find it fascinating. Thank you. What else is autonomous? Did you like that word? I am too smart.

I am just smart. I am just smart. Autonomous. Okay. What other parts of the body are autonomous? Well, he asked that. I know he did. And those are the two I can think of.

Well, you know, female eggs, Ova, or sort of semi-autonomous. They don't really have motile ability. The body moves those things around. So they just kind of shuffle them around with cilia. So, yeah, I can't think anything else. What about the whole autonomous nervous system?

The autonomic nervous system, you mean? Do you like that? I don't know how autonomous it is, but it is autonomic in that it operates without conscious. The hypothalamus just does it all for us. Well, we're not paying it. intention. Wainte you something. Well, no.

What about the thyroid, doesn't it? Just do whatever. It's only in the heartbeats, you breathe, you blink, people constrict. Yeah, you don't have to think about them. So if you think of it that way, then they're autonomous. Can you imagine if you had to think every time you breath? Yeah. Yeah, that's what means.

It's what means. Okay, I'm an asshole. Need take a breath now. These two. Need take a breath now. It's fine. I can't even say words, so I don't even know why I'm here. Isn't it funny that, yeah, we can control breathing?

Like I, yeah, like Tacey was just demonstrating. Do it again, Tase. It's awesome. No. I see you messing with your little keyboard there. Yeah, I was getting ready to push a button. Yes, you can control your breathing to a certain extent. You can hold your breath.

You can breathe faster and hyperventilate if you want to. But you don't have to think about it. If you don't want to, if you're doing something else, you're just breathing. but very few people can control their heart rate. Can you flap? Anyway, all right. They're just looking at it. It's totally fine.

It's totally fine. What were you going to ask? I'm not going to live it down. What were you going to ask? I'm going to walk away. I'm going to leave. Hey, Dr. Steve, Jeff Rowe from PA. Glad to hear you recovered from your COVID-19.

Thank you, my friend. My question of the week, I was out splitting wood. with a wood wedge, the big metal piece that you use to split up the larger pieces. It popped out of the wood and went right into my shin right down to the bone. Oh. Nice five stitches worth plus a little tetanus booster shot. Oh, fun. My question is, what is the effectiveness of the booster shots?

I'm 43 years old and probably haven't had a booster in 20 years. Okay. And if I didn't get the booster, am I still covered? No. About time we talk about other vaccines aside from the... Yeah, no shit. Agreed. Thank you.

SARS Coke, too. Yeah. God bless you. Yeah, you too, buddy. Hi. So, yeah, to my knowledge, and I would love to ask an infectious disease person that studied the history of this, there hasn't been a single person who died from... from tetanus that got the original three shots when they were kids.

I've only seen one case of tetanus in my career, and it was an elderly lady that never had a tetanus vaccine. So when you go to the pharmacy and you're getting a vaccine, they ask you, are you do a tetanus shot? Right. Who the hell remembers if they're due a tetanus shot? Well, that's why they should be hopefully keeping records. And they're doing better with that.

They are. There are some centralized records and stuff. So you want it every 10 years. And that's the shot that when you get it, it feels like somebody gave you a noogie in your shoulder. I think I'm going to do shingricks and tetanus at the same time, just get it all over with and have a hell of a weekend. So one of the things, when you have a wound, you want to, is it a clean minor wound? And has the patient had a primary tetanus diphtheria series? If the answer to both of those is yes,

if the most recent dose was in the past 10 years, you don't need to get a vaccine. You don't need a booster. Okay. Now, if it wasn't within the 10 years and they're presenting there. Yeah, then you go ahead and give it. Now, and that's right, and if it's unknown, if they completed a primary, you know, the first three shots.

Yes. Infectious disease is researching, changing it to every 30 years. That's awesome. And that's probably why the, the same sort of concept that if you had the original three. Oh, I'm sorry. Yes, she did need a bell. I mean, I've needed like five bills.

Give myself a bell. I gave you one, but I'm not giving you. Oh, she's had a couple. You've had a couple. No. Yes, you have. Nope. Two, right?

No, that's your third. Two to two. Oh. Oh, my God. Oh, stop. All right. Okay, no more. Can you please stop bullshitting?

Okay, so. I never bullshit. Assessing the wound. Yes, you do. Any other wound contaminated with dirt, fecal matter, saliva, soil, puncture wounds, evulsions, that's where, you know, the skin is just torn away, wounds resulting from flying or crushing objects, animal bites, burns, or frostbite. Then if you've had a primary tetanus diphtheria series, and it was within the last five years, you don't have to do a tetanus vaccine. but if it was more than five years ago or if you don't know

you should get the next dose right then and then if they have never had the primary tetanus series then absolutely you have to give them not only the vaccine but you've got to give them tetanus immune globulin because they are at high risk for tetanus

like if you step on a board in a cow pasture that is covered the board is covered by a cow plon and there's a nail in it, and it punctures your foot. Those are the kind of wounds that you've got to worry about when it comes to tetanus. Got it. All right?

Estimated half-life of 27 years. Yeah, that's awesome. Yeah, so every 10 years seems overkill. Yeah, 95% of the population is estimated to remain protected against tetanus and diphtheria for greater than 30 years without requiring further booster. Well, there you go. We're going to hearken to thine inner voice and give thyself a bill. No task shall be denied if they're not. I just like research.

I just have to look at whatever. All right. Just like what I realized. We did chronic ozone last time. I do. Let's do this one. Be mindful of its power. Just listening to your bulbs rinsing and not forcing it in there too hard.

Is it possible to really hurt your eardrum by forcing it too much? Because years ago, I used to work out of a shipyard up in northern Wisconsin here. And I had some beer wax in my ears. And they took a blaster, and they called it, get the dynamite out. And they blasted that water, and they're so hard, I mean, ever since then, my ears have been ringing like crazy. Oh, shoot. And that was in the late 70s. Yes.

Could that be why my ears are ringing? Yes. Thank you. Yeah, if it's temporarily related and they blasted it in there with the dynamite, then yes, that's probably what caused it. And what you may have is actually, you could have had a rupture in your eardrum, so let somebody look at it. They might still be able to fix it unless it's just completely ruined. Or they may have torn one of the small muscles away from, I'm sorry, the small bones in the middle ear away from its attachment.

Or more likely what they did was it was such a high decibel sound to the inner ear that actually damaged the receptor in the inner ear. And that's a problem. That's harder to fix. With our current technology, maybe impossible to fix. But seeing an ear, nose and throat doc, telling them what happened, and they'll do some audiology testing. They may be able to fine-tune a hearing aid that would have a parametric equalizer in there

to take out that one note that maybe you're hearing if it's just a single note. You know, it's a high-pitched ring. They can put a notch filter in there, all kinds of things that they can do. That's cool. They're really good at this stuff now. But see an ear, nose and throat that has an audiologist in their office and see if they can't work something out. Did you have something for that? No.

Okay. All right. All right. We did that. Oh, here's giant media erection. What's that about? It was just out, dropping my kids off getting guests, listening to the podcast. Oh, no. We haven't played this before.

This is a guy. He was listening. to the podcast in his car and just as he stepped out to get gas in his kids in the car by the way in their in their little car seat oh and just as he's getting out he hears me saying giant media erection for some reason or another yeah I'm sorry about that and I just did it again all right those are always nice here's a toe it says toenails for dr. why is it that when you get old okay we did that one already let's see okay Okay, here we go. Hey, Dr. Steve, this is John from Washington, D.C. How are you? Hey, John. I guess this is where I'm supposed to say, I'm just pretend we're having a conversation

and say, good, thank you. I had a question, a couple questions actually about weed. Okay. I just turned 40 and trying to give my liver a break and also slim down a little bit. So I have kind of cut out alcohol altogether. I didn't have a problem with it, per se, but, you know, would have at least one drink every night. Okay. And I still want my treat at the end of the day.

And I just don't like being alone with my own thoughts. So I recently, at 40, decided to start getting more and more into marijuana. Okay. And a couple of questions for you about that. But first of all, I'm scared of edibles and their unpredictability. So I've been vaping for the most part. Okay. I assume there's no free lunch when it comes to any sort of substances.

Did we do this? Well, I might be giving my liver a break. I don't think so. Is there a real risk associated with frequent vaping? We've talked about vaping before, but not this. We've also talked about free lunches before. Okay. With weed or anything like that.

And also, well, the thing I want to talk about is there was a longitudinal study that looked at non-alcoholic fatty liver disease. And there were some previous studies that suggested that cannabis use is associated with lower risk of non-alcoholic fatty liver disease. So this is people who have fat infiltration of the liver, probably caused by glucose intolerance or high carbohydrate intake or other, it could be genetic things. And they have liver disease, but it's not caused by alcohol. And so there were some studies in the past that showed that people who used cannabis had less non-alcoholic fatty liver disease. and so they were wondering if there was a relationship between the two. So they did a meta-analysis on a very large data set looking at lifetime use of cannabis

and then looking at non-alcoholic fatty liver disease and they did this thing called a sensitivity analysis. And there was really, in that case, no statistically significant effect between either lifetime cannabis use and the risk or cannabis dependence and the risk for non-alcoholic fatty liver disease. So it didn't hurt or help in that particular study. So there's no causal effect or protection against the development of it.

So if you heard that about those previous observational studies, which are bad data for the most part, then that you really probably can't use. I'm going to smoke pot to protect my liver. But if you're smoking pot instead of drinking, pot doesn't seem to affect the liver in an adverse way, whereas alcohol and Tylenol and other drugs do. So there may be something there. But, you know, talk to your health care provider. You know, if your state, if it's legal and you're using it responsibly, then, you know, go have fun. I think pot should be legal.

I really do. I've always said that. I do, too. It's putting it, making it a black market item really causes more problems than it solves. And legalizing it creates fewer problems than you would think. So anyway, all right. Well, thanks, everybody. Thank you.

That was a chaotic, but fun show. Well, thanks, Tacey. Well, that's not here to anchor us. Oh, so it was, okay. Okay, well, I'll tell you what, let's get out of here. And thank you all. We will not be doing drinking shows. shows any time. Yes, we will. Next Saturday, we'll see you.

Yes, and we will all be sober as Mike Judge. He will. Thanks, always go to my partner Tacey and my other partner, Carissa. Thanks to everyone who's made this show happen over the years. Listen to our Sirius XM show on the Faction Talk Channel. Siris XM. Channel 103, Saturdays at 7 p.m. Eastern, Sunday at 6 p.m. Eastern on demand and other times at Jim McClure's pleasure. Many thanks to our listeners whose voicemail and topic ideas make this job very easy.

Go to our website at Dr. Steve.com for schedules, podcasts, and other crap. Until next time, check your stupid nuts for lumps, quit smoking, get off your asses and get some exercise. We'll see you in one week for the next edition of Weird Medicine. Thanks, everybody. Goodbye, everyone. Thank you.