Weird Medicine: The Podcast - 553 - Asparagus-induced Malodorous Urine

Episode Date: June 8, 2023

Dr Steve, Dr Scott, DNP Carissa, and Tacie discuss: The science behind asparagus urine drug screen facts Ghost pills Post-defecation somnolence Hot v. cold water for washing Sundowning: novel treatment Continence and a$$play pudendal neuropathy hypothermia in the heat? Please visit: stuff.doctorsteve.com (for all your online shopping needs!) ed.doctorsteve.com (for your discount on the Phoenix device for erectile dysfunction) simplyherbals.net/cbd-sinus-rinse (the best he's ever made. Seriously.) RIGHT NOW GET A NEW DISCOUNT ON THE ROADIE 3 ROBOTIC TUNER! roadie.doctorsteve.com (the greatest gift for a guitarist or bassist! The robotic tuner!) see it here: stuff.doctorsteve.com/#roadie Also don't forget: Cameo.com/weirdmedicine (Book your old pal right now while he’s still cheap! "FLUID!") Most importantly! CHECK US OUT ON PATREON!  ALL NEW CONTENT! Robert Kelly, Mark Normand, the O&A Troika, Joe DeRosa, Pete Davidson, Geno Bisconte. Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices

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Fine. Jesus. Forget it. Anyway, cameo. com slash weird medicine. If you don't want Chris and Tacey doing it, then just go. to cameo.com slash weird medicine because it will just be me. Of course.

I'm just being an asshole too. Oh my God. Yes, I'm being an asshole as well. I'm trying to be funny because it's supposed to be a funny show and obviously failing miserably, so there you go. I'm really glad you explain that. Camio. Yeah, thanks.

Okay, all right, okay. All right, all right, all right. Lord and lady doze back. It's gone and defiance. Slight regard. contempt. All right, anyway. All right. You got anything else? Let's get going.

All right. Don't forget Dr. Scott's website. It's simplyerbils.net. Simplyerbils.net. And so, Tacey, are you ready for your time of topics? It's Tacey's Time of Topics. A time for Tacey to discuss topics of the day. Not to be confused with Topic Time with Harrison.

Young, which is copyrighted by Harrison Young and Area 58 Public Access. And now, here's Tacey. Yeah, yeah, Tom was kind of an issue. This week. So no Tacey's time of topics. No. All right, okay, then how about this one then? It's time for fast badge facts.

segment about everyone's favorite body part. And now here's your hostess with the mostest. DnP Carissa. What do you got? I already talked about the vaj. Oh, my God. Do we need more vajax?

All right, I'm just messing with you guys. I know you didn't have anything. Scott, have you got anything? Because I've got a couple of good phone calls. Oh, hell no. Okay, good deal. House candle on these two. Oh, but he doesn't get I mean, listen. Listen, he gets booed.

I ain't got nothing. Let's clap our hands for stone. All right. At least we're consistent. I mean, I was reading an interesting article. Don't take advice from some asshole on the radio. All right. Here's a good one.

Chris, you may know. Hey, Dr. Steve. It's Matt and Charleston. How are you? Hey, Matt. Good. I'm doing good. Hey, so can you talk about asparagus and why it makes your piece smell weird?

Hell yeah. Are there any other foods or vegetables that do the same thing? Thanks. You guys have anything on this? We've talked about, touched on this once before, but there's some new science on this. Oh, there's, yeah. No, I haven't seen the new stuff. Sulfur.

Yes, okay. Lucky guess. All right, well, okay. Give thyself a bell. Okay, we're starting out strong. Son of a. So, but it's not just sulfur, though. It gets broken down into sulfur byproducts.

Give thyself. All right. I'm not going to do this. Don't you dare. It doesn't know that. Tice you get jealous. Does anybody know what it is that gets broken down into sulfur

products, though? The asparagus? Chewed up asparagus. Well, that's because you're an idiot. Okay. I'm sorry. I thought we're talking about eating asparagus. What's in asparagus that makes it

asparagusy is this molecule called asparagusic acid. and the thing is is that when you eat asparagus in some people is broken down and you get this

sulfur containing compound that's extremely volatile and it smells sort of like rotten cabbage or metallic rotten cabbage or something it smells weird and the crazy thing is Not everybody produces or breaks down this molecule the same way,

and not everybody can smell it. And that's why it's controversial, because there are some people that cannot smell it, and it's called asparagus an osmia, and meaning not an osmia, meaning smell. And I never will smell it because the shit is disgusting. Oh, I love asparagus. You mean you won't smell it in yourself.

Yeah, I'm never going to smell that. Well, but if you're, no, I know, I know. Well, okay, but if you were in a public bathroom and somebody was eaten in asparagus. I would not know that does it smell like asparagus or does it smell differently? No, it smells like a thing called methylmercaptan. Oh, I would have recognized that. We used to use it in our organic lab. And it's also called methane thial.

And it's strong, unpleasant scent associated with fecal odor and bad breath. It's one of the most common odorants found in urine after eating asparagus. So this asparagus, which, by the way, is only found in asparagus, which may be why you don't like it tastes. It's nasty. Of course, you don't like it because your mother made you eat canned asparagus. Ew, gross. And it's green and mushy and it stinks. And then you sit there and go, I'm not eating it.

And they go, well, you're sitting here until you do. I remember sitting in my high chair. my mother gave me that shit I didn't even remember sitting in your high chair I remember I was sitting in my high chair we moved from that house when I was four so I had to be three or four and I remember sitting there and she's like

you're not leaving until you eat it and I'm like well fuck you I'm not eating it that's when you feed it to the dog yeah that and chicken levers man I've never tried it but there is a back pocket it in your jaw like a chew yeah slip a little twix cheek

and gum twin your cheek and gum Did you guys ever do the study and, say, high school biology where you have to taste this compound? They put it on a little piece of paper, and if you could taste it, then you were called a taster. And if you couldn't taste it, you were a non-taster, whoopty-do. I wonder how it came up with that name. And then you could trace it the gene through your family because it's genetically transmitted from person to person. I can't remember if it was autosomal recessive or dominant.

And I think it's recessive because it is kind of rare. And the thing is, my brother and I were both tasters, and he and I hate livers. And I can smell asparagus, too. So that may be the same gene or some related gene. And that's why, look, no one, if, and my brother agrees with me on this, No one would put liver in their mouth if it tasted to them like it tastes to us. There's no acquired taste to that.

It tastes like a lump of shit or what you would imagine a lump of shit would taste like. And to other people, they're like, oh, I love these. And it's like they can't taste the same to you. Now, we look at things like colors, and we all agree that the timer LEDs are red. But my red could be completely different to you. You know, there's no way for us to judge that my brain is translating that into the same sort of image in my, you know, um, um, uh, occipital cord, you know, the visual center and the acceptable cortex that you do. I see it as red. I can't describe it.

It's just red, you know? We see these colors and then we label them, but that could be purple to you. And actually, if you have blue-green, you know, color blindness, colors do look different. Yeah. So, kind of interesting. Anyway, so there you go. So that's the deal. And the smell can last 15 to 30 minutes after eating asparagus.

And within 25 minutes, half of the asparagus acid consumed has already been absorbed. It's crazy. So it appears quickly. I know that I've eaten it before and then gone to the urinal in a restaurant or something, and I can smell it. Anyway. All right? All right. I love it.

Let's do another one. And are there other things that do that? I'm not aware of any. You guys wear of anything that make, now there's stuff that makes your feces smell different. You think coffee makes your piece? Coffee makes your instinct. Does it? I think so.

Can you smell coffee, wouldn't you? I think it just concentrates it because it dehydrates you. Hmm. But you still smell it when you mean just concentrates the urine, you mean? Then that's just how I smell. No. I mean, I wouldn't know. Concentrated urine.

Concentrated urine still smells like urine just stronger. But I'm talking, but I can smell coffee in urine. Really? I don't think I've ever noticed that before. I have a very good sniffer. I do not. So, fuck. Very sensitive.

Huh. Yeah, I can smell coffee. There are people that make a living off of smelling things, you know, the perfumeries and the perfumeries and I saw it on 60 minutes or something. This is unbelievable smells. This person could, like, differentiate between like 15,000 different smells or something. Really? It's like, what? Well, how do they?

No, but they have like labeled in jars and say, well, this is vanilla, you know, Madagascarville and this is vanilla from wherever. Wow. Oh, yeah, this one's from there. That's pretty impressive. It was pretty cool. I mean, after all this time, we have just barely a rudimentary knowledge of how smell even works. Because it can't be just the molecules are binding to some receptors in there. There can't be that many receptors.

You know, they have a receptor for vanilla and cherry and chocolate and all that stuff. You also wonder if your brain didn't develop, you know, just a little bit better way of putting together those smells. Right, but how does it get the input, though? That's the thing. That's a good question. Nobody knows. It may even be some damn quantum phenomenon. It's just crazy.

I've got confirmation. Sean says he can smell his coffee and his urine, too. Really? Okay. Well, Sean says it, by God, it's right. Well, I'm going to be sniffing. All right. ABS, always be sniffing.

Always be sniffing. Yep. Just wanted to know for most substances, anywhere from alcohol to caffeine to hardcore drugs, marijuana. what's the detox time for a human to be completely clean? 90 days, a week, a month. Thanks a lot. Well, okay, to be completely clean, that's a different question from what we're in it. Is it detectable?

Testable. Right. So when you say clean, if you mean free of addiction, that's different for everybody. And, you know, like for nicotine, the physiological addiction, the withdrawal syndrome is about two weeks, but the psychological and the habitual addiction. can go on for months, if not years. So, you know, opioids are usually out of your system in one to three days. This is the, but obviously the detox takes much longer than that if you are, you know, addicted to it.

Cocaine, one to three days, ecstasy, two to four days, benzodiazepines like Valium and Ativan and stuff like that, one to seven days, methamphetamine, two to three days. And tricyclic antidepressants. seven days, and then marijuana can be up to a month if you're a chronic user in about a week. If you're not, the difference is that it is fat soluble, so it inculcates

itself into fat cells, which then release them back into the system very slowly. Now, let me ask you this, though. This points out an inequity in drug testing. So you're a company and you have a zero tolerance policy against all street drugs

and you consider marijuana to be a street drug. And then you, which would you rather have working in your office? Someone who is all coked up on Monday at work after a long weekend and tests negative on Thursday or somebody that smoked pot at a Lizzo concert two weeks ago and shows up positive on Thursday. Which one would you rather have working in your office? I mean, seriously. Oh, yeah.

So there's an injustice built into the system if you have a zero tolerance policy, particularly toward marijuana. because it just lasts so long. So methamphetamine, two to three days. I said that already. PCP, one to three weeks. So if you do PCP, and it's still out there. Is it really? Yeah, we'll see a couple of cases.

I was going to ask you what that even is. Fencycladine. It was an animal tranquilizer, right? It caused some sort of psychotic reactions in people. Like, back when it was really popular, people come in the emergency room, you couldn't restrain on them. and so we'd have to give them Domperidone

you know as an antipsychotic to calm them down but I want to throw this out there there is an oral preparation of dex metadomadine now so like ooh okay yeah I get it but dex metadomadine is also known as Presidex

which is a sedative that we use in the ICU particularly when you're trying to get somebody off a ventilator and it doesn't cause respiratory depression, unlike propofal, which is what killed Michael Jackson. That was Michael Jackson's magic milk. It was done improperly and basically killed him. And by the way, when it's done by an anesthesiologist, totally safe. Just don't have your doctor just come over and make you sleep every night using propofal.

Yeah, and I would recommend not making any important phone calls after a propol. You're right, right. Because, yeah. Do you have any personal experience for saying stupid shit after Pope Fall? Well, I just made a lot of things that were bothering me with my mother. Oh, my God. I made a phone call. Wait, this last time you did that?

Yes. We've not heard this story. Yes. We need to get our couch, the couch ready for her. Can you tell me the story? Do you want it on the radio? Can you make it so that it's not so... So there was something...

You don't have to say the things that you said. So the woman does things for people that she didn't do for me during a time in my life. That was very tragic. Yeah. And she just ignored it. Yeah, yeah, yeah, yeah. And so I just... And you called her on the phone after doing purplefoil and said...

Uh-huh. Asked her why. You'll do that for... But the problem is you feel perfectly... fine. You feel totally normal. There's nothing going on, and you are totally not straight. Right. Right. You just, and I knew that. It didn't matter. I was like, well, I'm going to call. We're going to work this out right now. Yeah. Did you work it out? Was there any resolution? I told her that if she argued with me, I would not speak to her for six weeks.

Okay. I said, I have to ask you a question. If you argue with me. I will not speak to you for six weeks. Okay. I would think maybe she would want to argue with you, so she didn't get any more phone calls. She did not. Well, anyway, so lesson learned on that one.

Yep. Now, we've talked about this before, but I always did my colonoscopies, DNP Carissa, with no anesthesia. And I highly recommend it, if you can deal with it, it's uncomfortable. The worst part about it is that if you're you know

they project everything on a big giant six foot screen and just before they enter your colon your asshole completely fills up the screen has to right it gets closer and closer and closer and then all of a sudden it just fills up the whole

screen you don't really want to see that so I would just avert my gaze just for a second until they get into the colon and then it's totally fine because it's parts you haven't seen before but uh and And then that's fascinating. You can see all the different parts of the bowel from the sigmoid to the transverse to the cecum.

And you can see the Iliosecule valve and all kinds of things you won't see on yourself. And there's times when it hurts a little bit, but it's not impossible. And when it's over, you just pull up your drawers, pass gas, unless they use nitrogen, in which case you will pass no gas, and then you just get in your car and drive to work. Do you thank them for the experience? Yes, thank you. That sounds good.

Thank you, sir. And then when they see you, right, when they see you in the hospital, they go, this person's awesome. They did a colonoscopy without anesthesia. I could not do an EGD, you know, the one from above, the electro, electro, esophagofagastro, duodenosis.

I could not do that because my gag reflex is so strong but I can all day long I can do a colonoscopy I don't know what that says about you I was going to say I think that's... It just says I don't like the Propheaval. Braggie bragging

not bragging I'm not saying that I know God damn you guys. I like stuff up my butt I like people sticking two cameras of my blood. Lord and lady douche bag so anyway that's that's you all right

all right fuck ball tree of you all right here we go hey folks quick question for you hey there's Stacy payload delivery of a drug injectables or IV that's blood

infusion or ozipic that's into the skin respiratory that's into the lungs and absorbed out of weight thank you for educating topical through the skin but the poor simple pill looking at that

from an engineering standpoint. How can they engineer that that it survives through the stomach acid? But once it gets into the smaller testes or larger tests, if they're long enough to be absorbed into the system before you crack it out, see it out. That is an issue, though. This is a great question. But I want to talk a little bit about ghost tablets.

so there are people who apparently obsessively look at their stool all the time and they'll go well that pill ain't doing nothing it goes right through me and it's potassium and long-acting opioids are the two big ones and the reason and they're called ghost tablets there's no medicine in them anymore it's completely leached out but they make them in a wax matrix

to make them last a long time to do exactly what Stacey's talking about in that question, so that it will last from the stomach through the small intestine, through the large intestine, and leach out the medication over a prolonged period of time. And then what is remained is this wax matrix. The scaffolding. Yeah, the scaffolding. Yes, thank you. Oh, okay. Yeah, I like that word. Oh, four. Give thyself a bell. One circuit. So, And you have to explain that to people Because they'll say, oh, it just goes right through me It can't be doing anything

And do you guys This is before y'all's time Tacey might remember this When Brooklyn Blowhard lost his tooth He swallowed his crown At a $1,500 crown And I had him digging through his stool For like three weeks

And it was like I felt so guilty about it, but it was so funny. And basically, you know, your transit time's around 24 hours. So it can be faster or somewhat slower than that, but it's never more than much of that. And so, yeah, if you swallow gum,

it's not there seven years later, folks. It's gone within 24 hours. And, yeah, but we had him. So how did you finally just tell him? Mm-hmm. Okay. Told him to stop doing it, that he must have passed it at some way.

that's rude it was early on and we were a little more shock jockey back then way to trying to be anyway way to be a douche doctor's dead I'm a douche but lord and lady doucheb this is what I told him

you get nothing so so so ghost tablets that's those things so that's one way that you can put medicine in a pill and have it, you know, be stable. And some things are, you know, he talked about stomach acid. Now, acid in our stomach, it's relatively strong, but it's not like if you swallow a penny,

it's going to dissolve it. It just doesn't work that way, and there are lots of drugs that will only break down in the presence of a basic environment. they will live through the stomach and make it into the small intestine where then pancreatic juices and stuff will neutralize it and then so because there are some things that are absorbed in the small intestine so and then some things are just absorbed in the stomach you know yes it's an acidic environment that's bad for proteins and sugars and stuff like that. And there's also enzymes in there that break sugars down. But, you know,

to just kind of get the work started with meat and proteins and stuff like that, that's really what the stomach acid is there for. And also is a barrier against some bacteria and stuff like that, although so many people in this country take proton pump inhibitors and H2 blockers to raise their pH because they have heartburn, that we kind of defeat that. And then what happens is they get bacteria growing in a slime mold in their small intestines. And what's that called taste? When they have abdominal pain and bloating because there's bacteria in their small intestine. H. Pallori?

Oh, now that's a good one. I'll give you a thing for the stomach. I don't know what you're talking about. I'm talking about small intestine. First of all, I wasn't paying attention. He's talking about SIBO. I could tell you were looking at me, and there was nothing that going on. It was the glossy eyes.

Tacey went to see Lizzo last night, and they got not only are they tired, but probably a little hungover. Extremely hungover. She and PA Jill went to see Lizzo. Yes. And then there weren't there, did you tell me there were young people behind you saying we hope we're as cool as those old ladies are, something like that? No, they were being very friendly about it. But they were like talking to us, but then one of them looks at the other one and says, I hope when we're that old, that we go do stuff like that together.

Okay. But they kept saying it, like, over, because they had been drinking, too. You guys are so old, but so cool. Yeah, that's not exactly a compliment. Intoxicated. She didn't even know what, she was just sloshing water around everywhere. I mean, it was just, it was crazy, but it's, yeah, it's bad bitch o'clock. Bad bitch o'clock.

That's right. Oh, well. It sounds like that. Bitch 30. That's every minute of my day. What about pills that are dissolved ODT? Okay. You want to talk about what that means?

Sure don't. I was asking you. Okay. Orally dissolving tablets basically break up in the mouth. Some of them can be absorbed through. the buccal mucosa some of those they just you're not trying to swallow a pill so if you're nauseated and you're trying to swallow a pill and you drink water with it you may just throw it back up but if you have an orally dissolving tablet you just basically swallow it along with the saliva

and you know if it's if it is able to be absorbed through mucus membrane then it will if not it'll hit the GI tract and be absorbed there so yeah but he's right it is There's a lot of technology that goes into making sure that if you give somebody a pill that it can be metabolized properly. There are drugs like, okay, so lydicane is an example, one I can think of, that is we use it to numb people up, but we also use it to stop arrhythmias in cardiac, you know, in the cardiac arrhythmias, sorry, I got my, Got my head turned around. So, you know, irregular beats or ectopic or beats that are out of time in the heart. And you can give somebody back in the day we would give lydicane drips for that. But if you gave it to them by mouth, it didn't do anything.

Well, the reason was it was just breaking the lydicane up in the stomach and bringing it down to its component parts. And therefore, didn't work. So they had to come up with a pro drug that would then, be absorbed and then the liver would convert it to lydicane and then it would work. So explain a pro-drug So a pro-drug is a drug for people. That has, that is

a molecule that may have bigger chunks of organic molecules stuck to it that when you take it it can be absorbed and then when it passes through the liver the liver converts it into the drug that you want.

A good example of that is a drug called soma, or Carissa Prodol, one of the most addictive muscle relaxers on the market. And it was originally sold as a drug called MeproBamate. And MeproBamate was a meltdown, look it up. It was taken off the market just because it was so habit-forming. And then when they took it off the market, you know, the manufacturer is like, well, hell, we got this drug, what are we going to do with it?

So they made it into a pro-drug called Carissa Prodol. And Carissa Prodol, when you take it, is absorbed by the stomach or small test, I'm not sure. And then it passes to the liver through the bloodstream, and then the liver converts it into Mepro-Bammate. And that is why, ladies and gentlemen,

we would put people on this stuff as a most relaxer could never get anybody off of it. Because basically, we're just giving them meltdown, but at the time, we didn't know the chemistry as well as we do know. That's what I'm named after. Really? Carissa ProDol. Yeah, it was my mom's favorite drug.

She's She's still out of her somies And if you remember Soma was the drug that they took in Aldous Huxley's Brave New World And then they named this fucking drug Well I guess I shouldn't say that

In case I this allegedly fucking drug You know After this panacea drug In that utopian Dystopian book Brave New World I wonder if now Would also be a good time

I'm going to talk about pH-dependent medications. There you go. I like it. Okay. For example. Wait a minute. Give thyself a bell. There you go.

Yes. You get a bell for that. Go ahead. For example, like when you take, because we know most of our listeners probably, 80%, I would say, take some type of proton pump inhibitor or. Yeah. True. Across America. If it's not working for you, take it about 30, 45 minutes before you eat.

Mm-hmm. Because you got to get all. those pumps fired and get that pH where it needs to be. You're talking about the PPI itself? Yes. Okay. Yes. All right. Because? Well, that's all I have to say about that.

Next. Okay. I mean, you know, certain, you know, medicines go through the stomach and different times in the stomach. It's different pHs. Right, right, right. So you're saying if you're going to take your proton pump inhaler. Well, I was just saying, 30 minutes before you eat.

Yeah. Because when you eat, it's going to fire up the proton pumps and then it will kill them. And the more you kill, the better off than you are. Right. The more that are active, the more it'll kill. But aren't other medications, pH-dependence? Sure. Yeah.

You know, pH being basically the ratio between water and protons, and protons equals acid. So it's a measure of acid. So the lower the pH, the more acidic an environment is. The seven is considered neutral, and then above that would be considered basic. And yes, absolutely. Every water-sliable thing has probably got some relationship with pH to some degree. So pay attention when it says with or without food. Yes, very good.

Okay. Yep, all right. Well, I would give you another bell, but it seems like it's redundant now. I don't feel like it is. Give thyself a bell. Very good. Very good, very good taste. Excellent job.

Damn it. Jesus. Quick question for you. You ever been just feeling just fine? And all of a sudden you get an emergency bout movement, and it is so brutal that you need to take a nap afterwards? No. What's going on with that? I mean, it's just so much energy exhausted at one point that you need to go to bed or what?

Have you guys ever experienced this where you take a giant dump and then you have to take a nap? No, but I do nap a lot and no. Well, and you do shit a lot. I do do that. It's like he had an orgasmic experience. Literally what I was thinking, you know, did he stimulate himself? And he was like, fuck, I've got to take a nap now. Colin and popped his prostate.

There are people that will exude prostatic fluid through their urethral meatus. There you go. When there's a, yeah, that's correct. Hey, yeah, that's my, that dang it all, man, I should be too to do that. That counts. Okay. Give thyself. Okay.

They will exude prostatic fluid through their urethromyalitis if they have a big giant turd. And that is because, do anybody know? Fluid dynamics. Fluid yes. Okay, you get a metaphoric bell. People are sick of hearing the bell thing. I've pushed it. We don't care.

Oh, we don't care. No, if it's two to two. Hey, there's got to be fun on both sides here. Yes. Fair enough. Well, you mean because of the relative proximity between the colon and the... Prostate, distal colon, prostate. That's right.

So the back part of the prostate is the front part of the colon. And if you have a congested prostate, what we call that blue balls, but blue balls is just basically congestion of the prostate from stimulation without emptying it out. Then if they have a big giant American turd and they pass that, it's just like massaging the prostate. and they don't have an orgasm, but they may get prostatic fluid that exudes out the end of the penis through the urethromedus. People think that they have an orgasm. Or like when the doctor checked my prostate, he made me ejaculate. No, they didn't. That's not an ejaculation.

Ejaculation is the rhythmic contraction of the seminal vesicles due to a spinal reflex that's in response to some spinal reflex that's in response to. sexual stimulation. But if you just stick your finger in somebody and push down on their big boggy prostate and fluid comes out the end, that's not an ejaculation. But doctors need to warn people about that if they're going to, by God, do a prosthetic massage so that they don't think stuff like that. Yeah. What else could make someone take a nap after the... Well, I was wondering... Stimulating the vagus nerve. You think? That's what the research is telling me. Okay, we'll expound on that because I don't know how the vaguely... nervous got anything to do with that go ahead tell us what you found i'm still reading oh my god

okay oh my god you can stimulate your vagus nerve causing a kind of euphoria yes well maybe it's trying a bowel movement oh you know what because they because of the straining is straining so hard chokes them out okay because you know because we do have older folks well that's true it may not be the bowel movement it could be the strain it could be a all right stace we figured it out according to the authors, this feeling which they call is Pooforia. Pooforia? That's a name for a new band. No, she didn't get one for that.

I don't deserve any bells. It's fine. I don't think so. I'm not welcome here. I don't deserve bells. Oh, that's not true. You're always welcome. Pufori would be a good band name. Yes. That's the name of this show is going to be Pooforia. The truth is. I better believe that. But basically, if he needs to nap after taking a shit, because he stimulated his He had a vagus nervous...

Give you a phone call. No, I feel like you might need to see a provider in regards to that. Yeah, I was wondering if it could be something like adrenal insufficiency or something because those folks, when they're not producing stress hormones, the adrenal gland is above the kidney, and it produces stress hormones, cortisol, epinephrine, nor epinephrine, that kind of stuff. And if you have adrenal insufficiency, any sort of stress hormones, strain can cause you to just end up having to go to bed.

They'll get a cold and then they'll just be so sick you almost have to put them in the hospital. It's like, you're a big baby. What's wrong with you? But if you check a thing called a cortisin stimulation test, you see it's wildly abnormal. Put them on five milligrams of prednisone and they're good to go. But I like your idea of the vagus nerve stimulation instead. And I was so fixated on stool coming out of the body. I wasn't thinking about how do you get one out of there. You've got to, you know, that val salm over.

Yeah, that's a good one. Thank you. Good question. Yep. Good question. Good answer from everybody. All right. Not me.

Dr. Steve, this is the bootmaster. Hello. Hey, I had sent you something after your discussion on the Patreon regarding washing your hands for 20 seconds or more. Okay. By the way, that makes the page. Patreon sound not very interesting, but, no, it's actually very interesting. And check it out at patreon.com slash weird medicine. Anyway, go ahead.

And I responded to you that back in the 70s, I was working at something called Mansfield Training School. It was a place for, at the time, called mentally retarded people. Okay. And at the facility during our training, you were only allowed to use when they told you about washing your hands only allows to use cold water. Right. They said that warm water or hot water, you could never get the hot water hot enough to kill germs,

but the cold water would kill germs. Now, okay, so they wanted you to use cold water because they didn't want you guys having people who were challenged mentally using hot water for anything. They didn't want them to burn them. So half of this is true. and half of this is bullshit. This is very interesting.

You're looking for your feedback on that? Yep. Because ever since, I've used cold water to wash my hands. It's fine. And I sing happy birthday three times. Yes. Love you guys. Be well.

Thank you. Can't wait to hear me your answer. Bye-bye. Goodbye. Thank you. My answer is just use your preferred water temperature because it doesn't matter. He's absolutely right that to kill germs with water, it has to be scalpel.

holding hot, so don't do that. Okay. But some people feel psychologically cleaner if they use warm water. Some feel psychologically cleaner if it's cold water. It doesn't matter. COVID, for example, doesn't like any kind of water. Right. It has a lipid coat and it doesn't do well in fresh water.

You know, the CDC says warm and cold water remove the same number of germs from your hands. the water helps create soap lather that removes the germs from your skin when you wash your hands. I don't know if you know how soap works, but we make soap from fats using a process called suponification. You expose it to a strong base

in the presence of water. And what happens is you get one end of the molecule is soluble in fat and the other end of the molecule is soluble in water. It's perfect. If you want to wash something,

so now most dirt is fat soluble, but some of it's water soluble. So if it is fat soluble and then you wash your hands with it, it will dissolve the fat type dirt and then the

water soluble end will allow it to be washed off with water. See, if you try washing your hands with Wesson Oil, what happens is that you have hands that are covered in oil and you put it under the water, and then the oil repels the water, you can't ever get rid of it.

But soap is like Wesson Oil that also is water-siable. And so back in, before they invented soap, my understanding is the ancient Egyptians used very fine, pounded sand, probably where the term go pound sand comes from, because they would get some, you know, never heard that term. Person to do it. Is that from like 19? 70 something, yeah, probably. Okay. Okay.

Can you like, shut up? So, um... Go pound sand, Steve. You never heard go pound sand? No. Really? It was before our time. I'm sorry.

Wow. Okay. It must be what you did for fun back in the feet. Have you heard go shit in your hat? Only from you, sweetie. Oh, go shit in your hat. Of course, nobody wears hats where they wear caps now. Anyway

Why would you shit in your hat? It was like you just tell somebody Go shit in your hat If you didn't like them Or you were arguing with them You didn't want to You didn't have a cogent response To whatever

Point they were making You'd just get frustrated And say go shit in your hat Yeah Or shit on you Shit Onions Shit on you is what we say Nowadays

Right shit and fall back in it Yeah shit and fall back in it Wow What did they say in Baltimore, D&B Christmas. Fuck off. Let's just fuck off. Okay, fair. Or nothing.

Just stare at you like, why the fuck are you even talking? So, anyway, that's soap. Oh, no, the ancient Egyptians would pound sand, right, in a mortar and pestle, and then they would dissolve it in oil, usually perfumed oil, and then they would rub it on their skin and then scrape it off with a knife. It sounds like a really nice spa procedure. Yeah, but for us, we could get in the shower, though, with soap and water afterward. You wouldn't, but I, you know, if you used to olive oil, maybe it would be okay. Maybe we should try that sometime.

I would let someone rubs that all over me and do it as long as it was in a professional setting. Okay. Why? Why? A professional setting. Let's just do it here. Okay. Yeah.

All right. There you go. She's easy. Just seem like something that needed to be done professional. I am a professional. He is professional. Yeah, I'm a professional. All right, here we go.

Here's a good one. Hello, Dr. Steve. I have a question. Yep. Yeah, I just called you. But my question, my real question, is people who have sundowners, if you get them a light, you know how they have the light for people that take melatonin at night. that slowly kind of wakes him up, turns on slowly. If you give them a light that turns on slowly as the day gets darker,

like their room or their area lights up more, do you think that would help with that? That's a good question. I think it's a great question. I don't know. My dad's having, my dad has issues, and he's showing, like, issues of sundowners. You know, he gets pretty bad at that time. I was just wondering if he thinks it would help, would it be worked a shot?

What is your opinion on that? It is a weird phenomenon, isn't it, that when the sun starts to go down, people, some people with dementia or delirium can just start getting wackier and whackier. And it's so common, we call it sundowning phenomenon. There is some research that, you know, well, first off, sundowning is not a standalone condition. so you've got to treat it in a multifactorial way. But bright light therapy has been in a couple of studies shown to maybe improve that. So because sundowning is related to sort of changes in their sleep wake pattern. And, you know, so increasing daytime sunlight, even artificially in the wintertime because there's more night time, right?

Fair. can help decrease sundowning behaviors and severity of the sundowning behaviors in patients with dementia. That makes sense. I thought he was asking if you put the light on when it was dark, that that would make it worse. Yeah, I would think so. Because you need to maintain sleepweek cycles. That is correct. I think what you could do is prolonged daytime with that, though.

So let's say, you know, in some places, particularly in the city, have you ever noticed that because there's high-rise buildings, that it seems to get really creepily darker way earlier than it should in the city because you only have overhead sunlight for a few hours, if that. And for those folks, if they're having sundowners at, say, 4 o'clock in the afternoon, why not try a light box? Until 7 o'clock at night. As long as it's consistent? Yeah, I feel like that's what would matter.

I mean, I haven't read any studies on that. That's right. Well, this study I'm looking at, they think that it improves serotonin. and endorphin levels, you know, it makes them more normal. This would not be a panacea for it. Obviously, there's neurologic damage and that kind of stuff, but it might be helpful, I think, worth a try. And it's cheap.

You can buy one of these lights at Amazon. I use mine every day. Do you have seasonal affective disorder? Yeah, do you? So let's talk about that for a minute. Some people in the wintertime have increased depression, and it may be due to this change in those sort of diurnal rhythms

and people do better that are exposed to bright lights during the day. So how do you do yours? My light? Yeah, no, your kombucha brewing. It doesn't seem to work. She's going to have to double the dose of light every day.

Okay, she's flipping it with me off. So, no, seriously, how do you do it? Fuck if I know. Oh, no. Oh, no. Now she's mad at me. Uh-huh. Look what you did. Yeah, good. Well, at least she's mad at you. It is all right.

I was both these motherfucking assholes. I turn it on. Okay. And I look at it. Yeah. How often? How long and for how long? Every day. Yes.

Anytime I'm at my computer because it is on my desk with my computer. Okay. Because it's very dark in that section of my room. Okay. or my place or whatever the hell. And so if I'm sitting there, even if I'm not on my computer, that's just where the damn thing is. I turn it on and I sit there. Usually, it has a little timer, so I usually set it to 15 minutes.

Okay. But, I mean. For real, can you tell a difference? Have you done an A, B test between not doing it and doing it? What do you think? Yeah, I don't know. I mean, sometimes we just do stuff because we do it. I don't know.

I mean, I drink, I brew my own kombucha. I can't tell you that it's actually doing anything for me. It's very good, though, we'll tell you that. It's very good. But you enjoy doing it, so it's not like you just do it for the fuck of it. True. So I feel much better when I use my light than when I don't, especially in the winter when there's, like, no sunlight. Yeah.

Or it's too cold to enjoy the sun. I depend on it. I mean, I am very, very affected by not having sun. Really? And, I mean, I find it in. So if you miss it for a day. day? Can you tell the difference? Probably not a day. Okay. But if I went a few days or especially if it was like a week, I went on vacation and I didn't take it with me. Yeah. And when I was in

Germany and so the weather was pretty shit a few times because October and rain. So anyways, I could tell a difference then. Okay. Interesting. Yeah. So worth a try. Worth a try. Yeah. They're not very expensive. And now if you can get him to sit there And what you want to do is don't wait till the sundowning starts You want to sort of have a period of overlap Between natural daylight and this thing And just see

You know if he likes to watch TV in the afternoon or something Just crank that thing up and And let us know But talk to your primary care I mean if he's sundowning there's other things that need to be done And I would just put it you know Somewhere that they're used to If they do the same thing

every night, just put the light there and... Easily accessible. They won't know that it's something different. Okay. Sounds good. So you're not changing their routine. Gotcha. We have a quit... No, no, thank you.

I love geriatrics, so I just go off when there's a geriatric topic. That's very interesting. We've got a mom swipes left. We'll probably do that one on the podcast. I've got a quick question on... Oh, here's a good one. Here we go. We'll do this one.

Hey, Dr. Steve, this is Dean in Northwest, and I heard one thing that they say is that the anal sex makes the butthole makes the ass bigger. My question is, does it make, do they mean that when they say that, do they mean that it makes the ass? bigger or the actual hole. Yeah, right. Okay. It's a good question. There's a lot of confusion about anal sex and ass play. And they've done studies where they take a pressure probe and stick it up someone's rectum and then have them clench down and see how much pressure they can apply.

And then have them do a bunch of ass play either with devices. or with human parts and then they have them come back and squeeze again and they can't squeeze as hard as they did before so there is a decrease in the anal tone but the good news is it doesn't matter because who cares as long as you're not just dropping turds all over the floor so and there's tons of redundancy when it comes to that anal sphincter and it's perfectly capable of doing this now go low and go slow and don't put anything up there that wasn't like a toy that wasn't designed for it no fruits and vegetables, no light bulbs, no Coke bottles because this is what happens

is you lose track of them and then they end up up in your sigmoid colon and you can't remove them and now you've got to go to the emergency room to have them removed and if it happens we've talked about this a bunch lately but I'm going to reiterate it The common fiction that we've all decided that we will accept is just say I sat on it.

And then that way you don't have to deal with, you know, feeling humiliated. You need to take care of that. Yes, absolutely. Don't let your reticence to be embarrassed in the emergency room keep you from getting that treated because it's actually a medical or surgical emergency. Okay, before we go, Dr. Scott, you have something from the fluid family, which is the chat room in the... YouTube channel. If you guys want to check us out,

we're usually there around sometime on Saturday. Just follow my Twitter feed at Weird Medicine. Don't worry. I won't fucking on a shit show. No, it's not you. Oh, I won't be here the next two weeks. Don't worry, y'all can go right on time. What they're talking about is sometimes we do

it at one. Sometimes we do it on Wednesday. There's no set schedules. There should be but, you know, with Saturday you're not cutting into our drinking time. Well, we're not pushing. We're not pushing the YouTube thing. It's just there for fun if people want to hang with us. So

anyway, go ahead. Yeah, so Vegas Cyclist. I have an itchy crotch. He is a male. How can I tell if it's a fungus or a rash? I've been using a fungal cream. He's been using Lomotron. Just wondering how I can determine what actually is causing the rash.

Okay, Lotriman. Okay. Did it get better or worse with the Lotraman? It doesn't sound like it got better. He wouldn't be asking us. I'm guessing. That's my guess. I'm guessing. That's my guess. That's smart. I think he's still on there, but... No, that's the problem.

DNP, Chris, is that when sometimes people ask questions, we don't get follow-up, so we have to sort of make assumptions. So assuming he's done it for two weeks and by the manufacturer's instructions and it's still there, I would look at it, get a mirror out and look. Now, if you have a black light,

you can shine it on there, and then if you see a bright pink salmon color, anybody remember what that is? I'm getting in the bell ready. That is. Aspergillus. No. Asparagus.

It's definitely. Astragalus. Bacteria astraglis. No, it's called erythrasma. And we actually... That was close. We actually had someone that called in recently and it turned out that they had it. Oh, shoot.

Yeah. So that was pretty cool. Oh, I remember that. Yeah, yeah. And erythrasma is a bacterium called... It's caused by coroninibatiabase. bacterium, and it has to be treated with an antibiotic, not an antifungal. Now, but he's a cyclist, and it's his taint.

This is what I'm worried about. Tacey's got the knowing, the knowing smile or nod. What do you think, Tase? Oh, you were like, yeah, yeah, like I know. Like, we're getting it ready to get the hell out of me. Okay, all right. Answers to Dr. Steve, you can go ahead. Wax on, Dr. Steve, wax on.

Jesus, crazy. Getting out of here. Okay, so. I'm a little concerned about pedendal neuropathy. I think he needs to get it checked out for sure. Yeah, yeah, absolutely. Yeah. So pedendal neuropathy is a thing that cyclists can get.

We usually think about pain in the taint and numbness in the scrotum and testicles. I mean a scrotum and testicle, scrotum and penis, but it can manifest, particularly early on, as itching. So as you stimulate those damaged receptors. So I would get, for sure, you know, get it looked at, but for sure get a seat that allows you to take pressure off your pedendal nerve. They make these ones that are just, you put your isheal tuberosity, that's your ass bone. If you're sitting right now. Yeah, it's where you sit on. And they have bicycle seats that only touch that.

and they don't touch the taint at all and I would highly recommend considering that because once pedendal neuropathy gets kicked in, then you just can't ride your bike anymore and it may or may not come back. Yeah, it may or may not come back

if you let it go long enough. Okay, so get that checked out. All right. All right. Now, we've still got we've got mom swipes left and people were complaining about my sweeper that I made so I'm just going to play it.

Dr. Steve. We have a question. I had a grandmother, and granted, she was 98. And this is from the Mom Swipes Left podcast. There are friends of the show, and they have great questions. They didn't like your sweeper? No, it wasn't them. It wasn't them.

It was people on Reddit were complaining about it. She's dead now. Back in the day, when she was kicking, she was always freezing cold. I remember this one night that we were having a cookout, and it was a super-fod. hot day. The temperature outside was 95 at least, if not more. And she was bundled up in a blanket and sweaters and all that stuff. And she was shivering. Her lips were a little blue. And everyone was worried that she had hypothermia. But I kept arguing that even if she was cold blooded had turned cold blooded somehow in old age, the outside temperature was enough to keep her

from having hypothermia. Can humans die of hypothermia in weather? That is above body temperature. Yeah, that's above body temperature. Because it looked to me like she could. Jesus Christ. So how'd she die? My mom pushed her off the step and she broke her hip.

Is that true? No, she actually died. She fell off a step at my mom and dad's house because she was living there. My mom denies pushing her. And then she had hips. surgery, and she threw her clot and died. Well, that happens, especially when your body temperature is so low. But, you know, if you have to say, I swear I didn't push her down the stairs, that's very

suspicious. It's like when certain people say, I swear, you know, the life of my kids, then, you know, why would you say that if you weren't lying? So, or when someone goes, totally true story, you know, it's a lie. So, so older folks. do feel cold more acutely than other folks do and they have a thinner layer of fat under the skin, making them more susceptible to cold, but conditions like diabetes, peripheral artery disease, and kidney disease can restrict blood flow and just lower their body temperature.

And so they're going to feel cold all the time. Also, old folk and not just old folk, but some people in this room can, also have low thyroid, which means they're going to feel, they're going to feel subjectively cold all the time. Can they die of hypothermia? No, but they can die of the peripheral artery disease, the diabetes and all that stuff. But you can have low thyroid and be perimenopausal and sweat all the time. That's right. Then you're just fucked. You're just fucked. I'm too cold, too hot. So you've got to treat all that stuff. What are you going to do? Yeah. So, but yeah, I'm going to going to say, no, you couldn't die of hypothermia, but you can die of all the things that make

you feel that way. And diabetic neuropathy as well could manifest as distortion in the perception of heat and cold. And in that case, you get old folks who are bundling up in 90, 100 degree weather, and then they die of hyperthermia because they get heat stroke. Because their body now, the core temperature is increasing and they're not sweating, so they can't get rid of the heat, and that's the end of that. So that's a possibility. So the perception of cold could kill them, but it's not going to be a hypothermia.

Excellent question. Excellent question. They always have good questions. They do. And they're funny. All right. Well, listen, thanks to everyone who is listening to this show right now. All four of you.

Thank you to Tacey. Thanks to DNP Carissa. And thanks to Dr. Scott. Listen to our SiriusXM show on the Faction Talk channel. Serious XM Channel 103, Saturdays at 7 p.m. Eastern, Sunday at 6 p.m. Eastern on demand, particularly on demand. And other times, it's Jim McClure's pleasure. And thanks to our listeners whose voicemail and topic ideas make this job very easy. Check out our Patreon at patreon.com slash Weird Medicine.

Until next time, check your stupid nuts for lumps, quit smoking, get off your asses. Get some exercise. We'll see you in one week for the next edition of Weird Medicine. Thank you, everyone. Thank you.