Weird Medicine: The Podcast - 563 - Tight Sphincter

Episode Date: October 9, 2023

Steve, Scott, Tacie discuss: Cellular treatment for solid tumor cancers, WORST STORY EVER! Meditation during vacation Alzhiemers vaccine Leprosy on increase in Florida Big turds and tight sphincter, can you stretch it out Undescending testicle talk Covid talk, going back in time........ Breakthrough Covid after vaccine Light blue eyes and sensitive to light? Shelajit is good or bad? bong smoke vs nebulizing seasonal allergies Please visit: stuff.doctorsteve.com (for all your online shopping needs!) ed.doctorsteve.com (for your discount on the Phoenix device for erectile dysfunction) simplyherbals.net/cbd-sinus-rinse (the best he's ever made. Seriously.) RIGHT NOW GET A NEW DISCOUNT ON THE ROADIE 3 ROBOTIC TUNER! roadie.doctorsteve.com (the greatest gift for a guitarist or bassist! The robotic tuner!) see it here: stuff.doctorsteve.com/#roadie Also don't forget: Cameo.com/weirdmedicine (Book your old pal right now because he's cheap! "FLUID!") Most importantly! CHECK US OUT ON PATREON!  ALL NEW CONTENT! Robert Kelly, Mark Normand, the O&A Troika, Joe DeRosa, Pete Davidson, Geno Bisconte. Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices

Why did the chicken cross the road? He got traded from the Yankees to the Mets. What did the father Buffalo say to his son when he left for college? Bye son. Why did the cat cross the road? Who knows why a cat does anything, honestly? If you just read the bio for Dr. Steve, host of weird medicine on Sirius XM103, and made popular by two really comedy shows, Opie and Anthony and Ron and Fez,

you would have thought that this guy was a bit of, you know, a clown. Why can't you give me the respect that I'm entitled to? I've got diphtheria crushing my esophagus. I've got Tobolabovir stripping from my nose. I've got the leprosy of the heartbells, exacerbating my incredible woes. I want to take my brain out and blasted with the wave, an ultrasonic, ecographic, and a pulsating shave. I want a magic pill. All my ailments, the health equivalent of citizen gain.

And if I don't get it now in the tablet I think I'm doomed Then I'll have to go insane I want a requiem for my disease So I'm paging Dr. Steve From the world famous Cardiff Electric Network Studios It's weird medicine

The first and still only Uncensored Medical Show In the history of broadcast radio Now a podcast, I'm Dr. Steve With my little pal Dr. Scott, the traditional Chinese medicine provider gives me street cred The Wackle Alternative Medicine Assholes

Hello, Dr. Scott. Hey, Dr. Steen. And my partner in all things, Tacey. Hello, Tacey. Hello. This is a show for people who would never listen to a medical show on the radio or the Internet.

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Take everything here with a grain of salt. It's an act on anything you hear on this show without talking over with your healthcare provider. Okay, very good. Please check out stuff. dot, Dr. Steve.com. Stuff. dot, Dr.steve.com. You just go over there.

You can click straight through. to Amazon, or you can scroll down and see stuff that we're talking about on the show all the time at stuff.doctrsteve.com. And check out Dr. Scott's website at simply herbals.net. And we'll talk about that in a little bit. Please, what? No, we, yes, we are going to talk about it at some length, as a matter of fact. Check out patreon.com slash weirdmedicine.

and patreon.com slash weird medicine. That's our show with Tacey and me and others from time to time where we just do things that are specific to that particular audience. And 100% of calls that come to that get read on the air. And we're going to be, I keep promising we're going to do live streams and stuff. We are going to do live streams. I just have to figure out the technology. And I have a real job, so I'm working on it.

I promise I'm working on it. I promise my shrink I would come up here after Tacey goes to bed instead of doomscrolling YouTube videos with Jimmy Dore all night and WATP and misery loves company and stuff. So that's my homework for this week. And hopefully what that means is I'll get this microphone fix. up here so we can have another guest in the studio again and I'll get the live streaming technology working and et cetera, et cetera. All right. All right. All right. Very good. And then I did two cameos this week. Whoopty do. They're five bucks. So because I like doing them and I think that's

the minimum that cameo allow me to charge. I would charge a dollar if they would let me. And I just, you know, say fluid to your mama. Somebody gave me a script and wanted me to play certain music in the background and stuff. I'll do that. I mean, I'll do whatever. For a small fee. Yeah, for an extremely small fee, you know, it's $5. I mean, what the hell?

It's just fun. I just like to do it. It's fun. I do not consider myself a celebrity in any way, but I will say stupid stuff to people. So cameo.com slash weird medicine. Check out Dr. Scott's website at simplyerbils. dot net, that's simply herbals.net for the best CBD

nasal spray. Is it the only CBD nasal spray? I'm not aware of any other. There are no others. I didn't think so. There may be, but if there is not as good. Not as great. All right, very good. All right.

Well, you know, I have a topic for today, and it is this city of hope. announced promising results for a new chemotherapy pill that appears to, quote, annihilate all solid tumors. Oh, wow. According to research, published August 1st in cell chemical biology.

So we're going to be looking at that one. Data from the preclinical research, preclinical research. In other words, not before clinical trials has so far demonstrated effectiveness in fighting cancerous cells, including those caused by breast, prostate, brain, ovarian, cervical, skin, and lung cancers. The health system stated in the release. So let's, I would like to look at the original paper here because this is some really breast. breathless reporting that's going on over this thing that has not been studied in a clinical trial yet. So in their summary for this paper that they printed in cell chemical biology, which is, listen, I'm not in the basic science thing, so I've never heard of this journal.

It says targeting transcription replication conflicts, a major source of endogenous, in other words, inside. the body, DNA double-stranded breaks, and genomic instability. Okay, so what they're talking about is just things that mess up your DNA could have important, and targeting those things could have important any cancer therapeutic implication. Absolutely. Totally agree with that. You know, some particularly spontaneous or even genetic cancers caused by some transcription error in a cell. that then goes, whoa, I'm more successful than the cells around me, and it starts to grow, right?

Right. So anyway, there's this proliferating cell nuclear antigen PCNA is critical to DNA replication and the repair process. Through rational drug design approach, we identified a small molecule PCNA inhibitor. And the molecule in question that we're going to be talking about is called. called A.O.H. 1996. It selectively kills cancer cells. This A.O.H. 1996 enhances the interaction between this PCNA and the largest subunit of RNA polymerase. Don't worry about that. Okay. So what it does is it induces, it fucks with

this system. Okay. That's the easiest thing I can say. Now, it says, it suppresses tumor growth as a monotherapy, in other words, by itself, or as a combination treatment, but causes no discernible side effects. Okay, first off, I don't like the fact that they use the word side effect. They're adverse effects. I mean, that's not really the scientific term for the side effects. Inhibitors of transcription replication conflict resolution may provide a new and unique therapeutic. So how have they determined that it doesn't cause side effects? So right now,

they are, I looked at, um, at, uh, clinical trials.gov. They are doing a phase one trial. It's undergoing. It's on, it's happening now. This phase one trial studies the side effects. I go, stop calling it that. And best dose. of A.O.H. 1996 in treating patients with solid tumors that do not respond to treatment. Okay, in other words, refractory. These are people who have been tried on other things

and then they're going to just throw this at them. And, you know, why wouldn't you? You know, if everything else didn't work, you'd try something. AOH, 1996, may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. So the objectives of this trial is to determine the maximum tolerated dose, so they're just going to give them more and more and more

until people go, stop, you're giving me too much. And then that will help them recommend the proper phase two dose. That's where they give it to a lot of people and look for efficacy. And then the secondary objective is to determine the pharmacokinetics. So this phase one trial, where they're like, it's in phase one trials. The only thing that they're doing, you get a lot, about 40 people, and the only thing you're looking at is what's the maximum dose?

They're not even looking at whether it actually works in humans. What I want to do over time, and I will look at this, is how did they determine that this was a molecule that they could give to human beings? Okay. Orally, you know, what process did they go through? They go through rats. They go through monkeys. What did they do? But anyway, the quote from City of Hope was,

City of Hope was able to develop an investigational medicine for a challenging protein target. We discovered PCNA is one of the potential causes, blah, blah, blah. Now that we know the problem area and we can inhibit it, we will dig deeper to understand the process to develop more personalized targeted cancer medicine. So this is, you know, this is, oh, you know, this is so new. Okay. We don't even know if this is going to do anything in people. Now, if it will, this is awesome.

Shoot you. But here's the problem. So now I'm just going to Google new cancer pill. And then let's just see what the headlines say. New cancer pill shows some promise. Many doctors say too early. Good for them. And that's actually fox9.com.

That's some local Fox station. Here's New York Post, New Cancer Hope, as pill kills tumors, thanks to little girl. Apparently, they had some pediatric patient that had recurrent tumors and they gave it to her. Let me see. Oh, here. Cancer-killing pill, in quotes, that appears to, quote, annihilate. All these breck. Come on.

This is way too early to be... It's an awful bold statement, isn't it? This early, yeah. New pill targets undruggable protein to selectively kill cancer cells. Yeah, I'm assuming that the cancer cells that were killed were killed in the laboratory. Now, okay, let's look at the New York Post thing. They're talking about this little girl, and let's see what her story is. Research has developed the drug, blah, blah, blah.

Okay, we all know the drug. Okay, oh, as A-O-H-1996 is named after Anna Olivia Healy, a cancer patient from Indiana. I knew I wanted to do something special for that little girl, Linda Malikas, City of Hope, and Duarte, California, leading cancer research center said, so when she was only nine years old from neuroblastoma, a children's cancer that affects only 600 kids in America each year, he said I met Anna's father when she was at the end stage if I could do something

about neuroblastoma and he wrote my lab a check for 25,000 which apparently the money opened their eyes a little bit to something and he said

that was a moment that changed my life my fork in the road yeah maybe okay maybe you could have paid attention to this kid without the check

but okay the dad was like you know hey can you do something. And let's see here. So young Anna's let me see. Okay. My wife

come on, did they give it to her and did it work? Now that we know the I, okay, we were too late to help him. Oh, yay. Oh, for God. That's terrible.

But we can help others like her. What is this? article. New Hope, Adialites also solid tumors, thanks to this little girl. Except for the little girl. That's a terrible story. That's a terrible story.

And the way that they're using them in these things, it's like you're assuming that what this means is they gave it to this kid and she's walking around today. I had no idea. I apologize to everyone. Well,

oh my God. These journalists should apologize. because New Hope as a pill quote annihilates all solid tumors thanks to this little girl come on well I

our hearts go out to Anna's family and she is a cute kid and I hope that maybe I don't know what the connection is between the dad sending 25 grand and them naming the drug after her I guess that's it but anyway

Good Lord. So stop it with the shitty journalism, please. You know, I have a real thing about shit medical journalism, and this is a pretty good example of that. If that's not the best example I've ever heard. Isn't that something? That's awful. Lord, good.

Show's over. Yeah, show's over. Yeah, show the last, dare, Dr. We should have shaved the best for last, Derek. It's anyway. Oh, my God. Holy moly. That's the worst.

God. I'm sorry. I'd just stop this show cold. So I hope, after all this, I really do hope that this is successful. But I really wish that these, I understand, listen, City of Hope is like, oh, we got something, we got something. This is a new story.

Stop going to the news. news and just publish your data when we have the data then you'll be famous yes and you can be famous then you can get the blow jobs yes then you'll be the wealthiest person in the universe or

just the blow jobs I don't think blow jobs and this little girl no I'm not honey it's poor taste saying that I'm not all right I'm talking about their motivation I know

what you're talking about okay well that's I've always said that you know when people call in and they say you you doctors are just suppressing the cure for cancer I always said that I would if if that were true if it was something like hey all you got to do is take this specific dose of vitamin D and we knew that but we were suppressing it because we want to sell people chemotherapy I would reveal it just for the blow jobs. That's what I always said. So that's what I'm talking about.

It's not for the money. It's complete, right. It's not the money. Jesus Christ. Anyway, you know, I get it that it's kind of in the same realm temporarily, but it's a different subject. But anyway, all right. Yeah, I can tell you're convinced. Anyway, this is some bullshit.

I don't think the molecule is necessarily bullshit. What's bullshit? is going to the press with it. Just do the work, publish your data, get through phase one, for God's sake, before you start getting these journalists all rubbed up on a cancer killed that annihilate solid tumors.

And we're rooting for you. Don't get me wrong. We're rooting for you to be right. Because, you know, I'm in my position right now because I didn't want anybody else's mom to go through what mine did. I absolutely don't want anybody else's family to go through what Anna's family went through. So if there's something there, go for it. But God, anyway.

Poor things. Yeah. Yeah. It just seem. Okay. Anyway. All right. Hey, next topic.

Yeah. It's distasteful. It's distasteful to me. It is. No, I agree. Okay. Act like you've been there before people. Yeah.

All right. All right. Tacey, you got some topics. I have a few. Okay. It's Tacey's Time of Topics, a time for Tacey to discuss topics of the day. Not to be confused with Topic Time with Harrison Young, which is copyrighted by Harrison Young and Area 58 Public Access. And now, here's Tacey.

Well, hello, everyone. So I only just brought up topics this time because Steve said last time I was talking a little, longer and well you did and so now we're just we're just doing i'm just doing topics and then we'll talk about oh no no no no oh yes so why our body and brain need a vacation spending money on vacation brings more lasting happiness than material things so doing meditation during vacation may help prevent fast decline of its positive effects so if you meditate on vacation then um you're positive effects last even longer. Not much agreement about how long a vacation needs to be, to get the most benefit.

Permanent. But the pandemic did cause stress, of course. Time off from work is good for our bodies and brains. It increases motivation, cognition, creativity, job performance, and even relationships. Old wisdom that says, what counts in life are memories of beautiful and meaningful experiences. Vacation increases daily sleep. Post-vacation sleep effects last about two weeks. Work engagement significantly increased, burnout decrease, which lasted about a month.

So this is a big duh, right? We all knew that. Right. So you should take a vacation every month? Is that what you're saying? Because the positive benefits only last one month? I think they last about five fucking minutes. I got back to work and I was immediately burned out again.

After a two-week vacation. Yeah. Yeah. I believe it. Which wasn't the most stress-free vacation, to be perfectly honest, just because our kid got engaged and there was other stuff going on. Oh, my gosh. Topic number two.

A new vaccine shows promise of slowing or even preventing Alzheimer's disease. It targets the most common cause of dementia. The vaccine, eliminates toxic cells in mice with the disease. It's called the SAGP vaccination, and it showed fewer amyloid plaques, decreased inflammation in their brain tissue, and increased behavior and awareness. Okay, so this is a rat study. Yes.

This is, again, preclinical. So that's interesting that they've got something. I've got here's something. This is from the American Heart Association. So that's a decent website to go to for stuff like this. Novel vaccine may hold key to prevent or reduce the impact of Alzheimer's. Now, look, it says a novel vaccine targets a protein involved in Alzheimer's disease. We call it dementia of Alzheimer type, but anyway, because Alzheimer's, the guy, doesn't own the disease.

You know, these eponyms have got to go away. But anyway, helped eliminate toxic. cells in mice with the condition. And after the vaccine, the mice had fewer amyloid plaques and less inflammation in the brain that showed, and here's the important thing, showed improvement in behavior and awareness. Now, if we can come up with a vaccine that will prevent Alzheimer's disease, hell yeah, I'm all in favor of that. let's see some human data but that is kind of that's kind of exciting i'm cool with talking about

research just don't make any claims and don't drag families into it and stuff for god's sake oh my god we're all going to be scarred yeah anyway yeah uh dementia of Alzheimer's type accounts for 50 to 70 percent of dementia patients worldwide there's other types of dementia from temporal dementia, aka. Pix disease, where people have this burst of creativity and all of a sudden they start painting or playing music and stuff

and then their behavior starts to change and then they just decline. It's like the fly. Remember the fly? In the beginning he had all these cool sort of superpowers and then he got weirder and weirder and then he just completely declined

and literally turned into a monster. And that was kind of an allegory for how Picks disease works because you get this huge burst of creativity where people all of a sudden become great painters or they become

great poets or musicians or whatever and then they stop taking baths and then they have difficulty maintaining relationships and then they decline so anyway and then there's vascular dementia that's where you have

lots of basically many strokes that attack parts of the brain. And those people will decline in a stepwise fashion as opposed to a gradual fashion like Alzheimer's does. So anyway, okay. Topic number three, this is interesting. Leprosy could be endemic in Central Florida. Yeah, what the hell's going on with that? Yeah, this is from the CDC. Here's what to know. Central Florida accounts from one-fifth of cases reported across the U.S., 159 cases in U.S. in 2020. In 2015, experts blamed Armadillos for higher than normal leprosy

cases in the state. Damn you! Leprosy occurs when bacteria called mycopacterium leprera attacks the nerves, which then becomes swollen under the skin. You can

lose ability to sense touch and pain. Advanced cases, of course, you can lose fingers and toes. It is treatable, however. You can get it when a person with another word for them to call leprosy as Hansen's disease. Correct.

Coughs or sneezes on you. Again, Hanson doesn't own it, so. It's treated with two or three antibiotics for one to two years. Early diagnosis is key, and that completes my topic, my time of topics. Those are very good. Those are great topics. Yeah, so how do you diagnose leprosy? There's weird patches of skin.

They look lighter or darker than normal skin. And then they have loss of feeling. And there was a book or a series of books about a guy that had leprosy called, oh, shit. Now, I can't remember. Stephen R. Donaldson. Oh, God, I got to look it up. White gold wielder, I think.

And this guy had leprosy. and he would go into this other universe that was ruled by magic and when he was there he didn't have the leprosy but he had a white gold ring and apparently that was exceedingly rare in that universe and it carried with it like magical powers

but he didn't believe it you drove you crazy, you wanted to strangle this guy because he kept thinking he was in a dream and he wouldn't use his power you know he could have fixed everything but anyway that's talked a lot about

the symptoms of leprosy and stuff that he had but yeah it is treatable. There are antibiotics there's a cocktail of antibiotics. Did it say which ones that they used? No it did not but it did say you had to take it

one to two years. Okay well let me look it up then it looks like you have to take a combination of dapsone, ripapacin, and and Clofazamine, and it's called multi-drug therapy. I wonder why.

I wonder why they call it that. Thanks for letting us know, W.H.O. Yeah, when you take three drugs, it's called multi-drug therapies. It's very strange. Where did they get that term from? Ugh. You see? You see?

Your stupid minds. Stupid. Anyway, it says that the multiddle drug therapy kills the pathogen and cures the patient. Obviously, early diagnosis and prompt treatment prevents disabilities. So, wow. Wow. Why central Florida, though?

Why blame it on the armadillos? It did not talk about why they blamed it on the armadalee. It just said that it was blamed on them. Huh. Why is leprosy? Do armadillos go around biting people? No, I don't know. I don't think so.

I think armadillos are pretty laid-backed craters. Yeah, they just kind of walk away if you don't mess with them. Huh. They're excrement. People aren't fucking armadillos, are they? No. Let's hope not. Oh, for God's sake.

No, that'd be weird. Stop it. This show has gone for bad. This show is terrible. You're terrible. It's awful. Now, 95% of people. Now, they may be licking armadillos, you know, just kind of licking.

You think that's like a thing, like people licking toads? Yeah, or licking their car or something like that. Someone told them that licking an armadillo will get them high, or it's an aphrodisiac. Exactly. Now, here's the thing, 95% of people are resistant to this. Oh, wow. There's only a subset of people that can even get leprosy. It says it should be assumed that the infected armadillo could be a source of infection to a susceptible person in contact with its bodily fluids

or organs. So maybe, and it's not been identified in any other wildlife. And the CDC advises, okay, thank you to avoid contact with armadilloes whenever possible.

Thank you. Thank you, Captain Obvious. Really. Yeah. Okay. And if you become in contact with an armadillo, pillow's bodily fluids.

Again, I'm raising the question. No, don't you do it. Don't you do it. Then you should be seen by your health care provider, and they will monitor you over time. Okay. I didn't know people could be immune, I guess, to leprosy. That's interesting.

Yeah. Yeah, you have to be actually genetically susceptible to it to even get it. Isn't it well? Yeah. All right. Do you guys want to... Number one thing. Don't take advice from some asshole on the radio.

That would be three assholes on the radio today. Well, there's... No comment. Me and... Lord and lady do you back. All right. Let's get this going here. Oh, my goodness.

Uh-oh. Oh. Uh-oh. Okay. Dr. Steve, long-time listener, back in the O&A days. Hey, thanks me. Hey, I was 10 years old, realized I only had one testicle. Uh-oh.

Because, you know, you're with the buddies and obviously realize they've got two. I've only got one, so I'm missing one. I realize that. I tell my parents, hey, I'm missing something here. We go to the doctor. They look around, can't find it. They think, well, maybe it's going to drop. Never.

They can't find it. It's never been there. The only kind of record they have of it when I was born is when I was six months old. I had a hernia surgery. Could that have possibly done anything? Just checking. I've been fine. I got three kids doing great.

Just one nut, though. Never found out where it's that. Thanks, Dr. Steve. No, dude. No, okay. Wow. Yes, the hernia surgery could have done something, but it's possible that they killed the blood supply to your testicle. who knows, particularly if it was on that side,

because all of those things flow down the same pathway that the hernia goes, so it is possible. But it'd be good to know. I mean, a urologist could go in there and maybe find a residual. You'd dry it up, raisin-looking testicle. With an ultrasound in your sack, because what you want to know is that it's not,

retractile or has never descended, non-descended testicle. Non-descended testicle increases your risk of cancer. So it'd be good to know where that thing is. So if it was in your sack and they killed it, no big deal. You got another one. Too late

to sue anyway. And there's nothing really to sue over, no real damages other than... Three kids and all that. Yeah, yeah, yeah. You're good on that. But it would be good to know where that testicle is and if it's still there. I would see a Urologist, tell them your story, say, I'm concerned that maybe I had a retained or non-descended

testicle, can you help dope that out? Because if it was in the sack and it's dead, that doesn't increase your cancer risk. But if it's up in your body, that does. Okay? Makes sense. Yes, sir. Okay. Makes good sense.

I wanted to get that one out there. There we go. Hi, Dr. Steve. Hello. Time to get back to the fun. questions. As we get older, does our sphincter, or as some call it, bunghole, become less elastic or stretching? As a 50-year-old male, I feel a little more strain pushing past the sphincter when having a normal bowel movement. Is there anything to bring back that

stretchy sphincter? Thank you. Sure, but what happens as we get older, particularly if you've had giant American turds that we have caused some scar tissue in the old sphincter, little microtairs and stuff like that over time. And yes, that will decrease the elasticity. He says he's having to strain a little bit more to have a, what he calls a normal bowel movement. I would ask, you know, how do you define normal? And I wish I still had the citrus cell drop because that's what I would recommend is just

adding more fiber to his diet and more fluids. Drink more water, take some citrus cell. It's methyl cellulose. It's what they made slime out of in the, oh shit, Ghostbusters movies. Ghostbusters movies. And the bacteria and your gut can't crack it so it doesn't cause gas. It's the only one of those that doesn't. And it'll make your stools more fluff.

and delightful. What about internal hemorrhoids? Yes. What about them? Could that have anything to do with it? Well, sure. Yeah, if you have internal hemorrhoids or external hemorrhoids and eventually they scar down. Or fissures, anal fissures will scar down too.

And just microtrauma, you know, because now. Years of scarring from big. I'm guessing that you could go in there and take different sized anal anal. Like a stretching device. Yeah, dilators. They have anal dilators, and you go bigger and bigger and bigger. They have vaginal dilators that do the same thing for women that were born with vaginal atregia, you know, abnormally small vagina. And you go larger and larger and larger.

I'm not sure that that's required here. Yeah. Unless it's really pathologic. In that case of it is, he needs to see a proctologist. Make sure there's no real scarring that needs to be. Or some other problem that's causing him to have to strain. Their proctologists are just general surgeons that deal with ass issues. And there are so many of them that you can actually specialize in proctology if you, and you say,

why would anybody do that? Actually, the procedures they do are pretty fun. You know, they have some fun procedures. And they can help really quickly, too. Yes. And yes, and people will come in and they're miserable because you never think of your stupid anal sphincter until it causes a problem. And then that's all you can think of. Yeah.

So if you live in a city large enough to have a proctologist, go see one, if not to see a general surgeon. Just make sure everything's groovy down there. And then if it's just that you're a little bit older and your diet and you're not drinking as much fluids, then I think your version of normal stool has. has drifted a little bit. Just like the definition of being left of center has drifted some, you know. You know what I mean politically? All of a sudden, you have people like Elon Musk going, well, hell, I'm right wing all of it. Why, how did this happen?

He's not the only one. That is something that a lot of people have felt. But anyway, all right. Here we go. Yeah. Okay, so I went way back into the voicemails and found some COVID stuff that I thought would be kind of fun now in retrospect. And here's one that I thought was kind of interesting. We'll see if it is.

Hey, Dr. Steve, this is Rob from Fredericksburg. How you doing today? Good, man. How are you? Okay, hold it there. Enough about you. This is all about me. I just wanted to get out of me.

I've been discharged from a rehab facility. I did about 30 days before. I unfortunately tested positive for COVID. Oh, yeah. So I'm back home, spending out the next few days under quarantine before I continue on my regular life. But I'm just kind of curious if you had any information about people who were vaccinated, like myself, and the odds of them actually getting the COVID virus. We'll love to hear the answer. I'll talk to you soon.

Bye, bye. Yeah Vaccine Breakthrough is what he's Is what he's talking about And I had I was vaccinated I was too

And yeah Tacey was vaccinated As far as we know She was She never got it Oh wow I was vaccinated And almost

Probably fucking died That's what I think Probably Yeah Stevie got it Bad Yeah

He's old Yeah, so here you go. So if you're 65 plus and you were unvaccinated, the numbers were like 62% of cases were unvaccinated, but 29, 30% were vaccinated without the bivalent booster and 14% were vaccinated with the bivalent booster. Now, if you look at people who are 50 to 64, it was 5% vaccinated 4.4, 4.4,000. I'm sorry, 5% unvaccinated, 4.4 vaccinated, and without the booster in 3.6 width, so the numbers are almost no difference. And then if you look at the young people, you know, 3.3, 1.9, and 1.6.

So it decreased it a little bit, but there's, you know, it was almost the same number of people. Right. So the vaccine tended to not prevent you from actually getting the virus, didn't prevent you from transmitting the virus. What we did see was a decrease in hospitalizations in people who were vaccinated. So anyway. And then now if you look at this, unvaccinated people, this is the CDC, of course, 1.7 times more likely to be hospitalized. but it doesn't mean that vaccinated people were not hospitalized, right? Right?

Yeah, just more likely to be hospitalized, but, you know, if you're vaccinated, you're still got hospitalized. So anyway, yeah, and if anybody thinks, I mean, if YouTube wants to strike our channel because I'm saying these things, I mean, this is straight from the CDC. And the other thing is, I'll be happy to show anybody what COVID did to me. my lung vaccinated and with the monoclonal antibody, where I had to go to a, you know, a cardiothoracic surgeon to consider taking out part of my lung. They decided not to do it for right now. They're going to wait a year, but that still may be a thing. And I had the vaccine before anybody else.

I was in the vaccine trial with Pfizer, so I had my first vaccine in September of 2020. got the virus during Delta of September of 2021. Can't believe Tasey and back in Liam didn't get it. So that's why I'm wondering, if we did antibodies on you guys, I bet you would be positive. You just had asymptomatic cases, which was also a thing. And, yeah, I had the antibodies. The next day was basically well the day after that

and never missed a day of work, except I had a cough for about six weeks. And a year later, they found this giant, well, giant to me. An eighth of my left lung was just completely destroyed. So I can't imagine what would have happened if I hadn't had all that. I'm going to have to assume that those things help me. Yeah. Absolutely.

When is the next time you have a scan or an image of your lung? Yeah. That's a good thing. They're going to see if it gets infected again. I had to drive to Florida while Tacey and Beck flew because I, that place got infected. And the problem with it is, when you have scar tissue that big in your lung, and if it gets infected, it can't clear it. There's no cilia in there.

The white blood cells can't get in there. It's a problem. I had to take antibiotics for a year. I considered filing a workman's comp claim, but there's no real, you know, there's no cop unless I could just make sure that my medical treatment going forward was covered. Yeah, which is important. That's not a bad idea. Yeah, well, I've got literally 13 days to do it. File the claim.

Yeah, filed a claim. So, yeah, so that's a really interesting question. Back then we didn't know. This guy was like, well, I got vaccinated. What the hell? How did I end up with COVID? Now we know that people who got vaccinated still got the virus. You know, anyway.

All right, we'll be talking about this shit forever. Ever and ever. All right. Hello, Dr. Steve. This is John from Chicago. How are you all doing? Good, man. How are you doing?

I hope you're well. Great. I'm doing swell, too. Excellent. Thank you. You're welcome. Hey, I have baby blue eyes. Always had them.

Excellent. And some people say they like the look of them. The older I've gotten, especially, I hate them because they are so much more sensitive to light, and because of the lack of pigment. Is there, two questions. One is, does everyone's eyes just get more sensitive to light as we get older? And number two, for people in the blue eye category such as myself, is there anything we can do to make our eyes more tolerant to light exposure?

as opposed to just wearing sunglasses all the time, even when it's like, you know, overcast out. That's how much of a baby I'm at. And I assume staring directly in the sun is stupid as hell. Yeah, don't do that. That's stupid whatever kind of is you have. I don't know. I'm just curious if there's any way to train the old eyes to handle light.

Anyway, thanks a lot. Love the show. Yeah, it'd be nice if you could, if there were just a switch, you could just turn down the signal that's going to the brain. But it just transmits whatever signal it wants. The iris is supposed to control some of that. And so when you're exposed to light, there's a circuit that says, okay, there's a certain number of photons hitting the retina.

It sends a signal to the muscles of the iris, the colored part of the eye, that decreases the pupil size. But the problem with blue eyes is the iris itself is translucent. so it can close all at once and the light still gets through so it seems to me one thing that you could do is you could wear contact lenses that change the color of your iris yeah the dark yeah that would be one thing but it's pain in the ass yeah they're really cool though they are cool yeah you can have all kinds of head eyes wacky wacky colors and stuff neon yeah uh the other thing that you could consider doing, which

I have no, no, don't do this, but I know, don't consider doing this. Let me take that back. But I have heard of people who have tattooed their iris. Oh, I knew you're going to say that. No, I have to. Don't do that. Don't do that. But if anyone has done that and they've had experience

with it, let us know. I don't have any data on that. Now, the other side of it though is because they are more light sensitive, what would follow from that? What benefit could there possibly be from blue eyes? Girls think we're more handsome.

Nighttime. No, I think it's because girls think we're cute or because we have blue eyes. Well, it is weird that that must be some, there must be some genetic benefit that we don't know that would make women want to mate with guys with blue eyes. That is weird. I think it's because we're the minority. You think that's what, that people like, that women like minorities? No, I'm just saying.

That somehow that gives you a, that gives you an advantage. A uniqueness, a uniqueness, yes, that's what it is. People with blue eyes tend to see better at night unless there are bright lights. In that case, the lack of melanin makes them sensitive to light at night as they are during the day. But that would be the only thing. Now, he asked another question. When you get older, do things change? Yes, there are some conditions.

If you notice that you are becoming painfully light sensitive, you could have a couple of medical conditions. One of them is dry eyes. You would also notice that as you look at a computer screen after time, it starts to become blurry or hard to see. Get some, you can buy over-the-counter eye drops called Custane Ultra. Those are the ones I like. Put them in and see if that makes a difference. But either way, see your eye doctor. if you're noticing light insensitivity, I'm sorry, light sensitivity because glaucoma is also a cause of that.

And glaucoma being increased, usually caused by increased pressure of the brain. Shit, increased pressure on the inside of the eye that causes the retina to deform and sending signals to the brain that are incorrect. And so that's one thing, and that can cause blindness, so go get your eyes checked. They check the pressure in your eye every time you go. It's very simple. They can do it with a little puff of air now. And so get that checked. And there are other things, too, that could cause inflammation inside the eye.

Retinal detachment. Normally you would see flashes of light, but it could cause increased light sensitivity. and UVitis, which is an autoimmune inflammation of parts of the eye, those can cause light sensitivity as well. So if you notice that, just go get it checked. If you do and you heard us say this and you went and got it checked and that's what it was and they saved your eyesight, let us know. I might need it.

Hey, can I say before you get the next subject you real quick? Yes, of course. If you have really light eyes like I do and I'm sure like... I've never noticed that you have blue eyes because I'm not in the habit of like gazing into the eyes a man that I know. I think you only see the red swollen eyes after my... I just see the man. My emotion.

That's all I see. So anyway. That's all anybody sees. That's probably true. Sunglasses are vital for people with light colored eyes for sure. And hats are vital too. If you want to save money on Botox, the women and the man out there, wear sunglasses when you go outside.

It's the number one thing you can do to prevent those wrinkles. And all of my stuff, my house, my office, everything is really, really low light. I mean, I even cover like the lights, so the light's not so much. I see better when it's a little bit lower light. That's interesting. Wow, yeah, that's interesting. So my concern would be for him just to make sure that, you know, eye protection is really important. And transition lenses may be the thing for people with blue eyes.

They actually work pretty well now. These are lenses when you go outside, they get darker. and when you come inside they get lighter and they're still crazy expensive but if you have problems with light sensitivity that might be worth the money I really like mine I really really like them

I haven't been wearing my glasses I've never seen you wearing your glasses she doesn't have to reach she's tired but when I do wear them I really like them yeah makes a big difference well she's special if she surely is

all right well let's uh take this one here hey folks don't think you've ever heard of something Scott it might be more Scott's one that's a familiar voice but Sheila G. Rawson I've been doing this about the last two months

just to see if it helps anything stuff is disgusting but I was also trying to find just some decent information about it didn't know if you do anything about it or not thank you here bye

wasn't Sheila G the drummer for Prince and I was Sheila E. No, I was thinking of the same thing, Sheila G. Sheila G. She was awesome. She was awesome. No, she was awesome, but I, what the hell is he talking about?

You tripping. I'm looking. Oh, I found some rosin. Okay, you did? Yeah, but I don't know if this is right. No, I know, I know marijuana, you know, they make a rosin. It's pretty drunk. Shella, she said.

He may be. It did. Did it really? I don't have anything. Well, rosin is a different thing. Well, but now they use these. Oh, Sheila Jeet.

Yeah, Sheila Jeet. Oh, Sheila Jeet. Resin, yeah. That's different. Okay, you know what that is, right? Sheila Jeet has been used for inflammation. It's fulvic acid. Yeah, well, okay.

Now she's that. I was, I was like, man, I love Sheila G. She was awesome. Yeah, it was Sheila E. Except, of course, she was Sheila. Damn, I'm a regular Jane. God, we're just, yeah. He's a fucking idiot.

I think they use it as a for inflammation and toxin. It's like a... It's scraped off a rocks is what it is. Right? Yeah. And I think it's probably just fine as long as you don't have any side effect to it, no.

Says here, Sheila Jeet is sometimes referred to as a... Is that what I said? I think Sheila Jit is correct. You are right. Oh, okay. It is referred to as... is a mineral tar or resin, but it's not actually either of those. It's a highly viscous substance like tar or resin that's very dark brown or black in color,

but unlike these is readily soluble in water, but insoluble in ethanol. It's composed of 60 to 80 percent humic substances such as humic and fulvic acids. Wow. Which means it's a big chelator, you know, it's just... Oh, is that why there? Yes, okay, all right. Interesting. Yeah.

I'd say take it and see what happens. Well, okay. Unless it's toxic. Hey, listen, we know who it is. He's tough. He can handle it. And for $100, he'll do any of the research. Well, now that is true.

Okay. It says natural phytocomplex with potential precognitive stuff. Okay. Increases spermatogenesis, combats anemia boosts. Aha. Now we know the testosterone. Now we know. We're getting to the bottom of it, it increases his seminal fluid.

Sheila Jeet can increase testosterone levels in the body. I want to see data on that. But I will, okay, will you put that down for next time? And we're going to do, maybe Tacey could do a Tacey's topic on Shalajee's topic on Shalajee. And see if there's actually any, here's something. How do you spell it again? S-H-I-L-J-I-T. I'll show you, Tase.

I wonder if you did a comparison. between Sheila E and Sheila Jeet, which one would cause a better testosterone? A better erection. Okay, it says here, this is from national something of health here. Let me see National Library of Medicine. This is a potent and very safe dietary supplement, restoring energetic balance. Oh, this sounds, this already sounds biased and potentially able to prevent several diseases. Okay, so we're going to see if there's any actual data on this that is worth anything,

and I'm always interested in new supplements that I haven't heard of before. Oh, yeah. By the way, you know, the data that said, or the article that said, Torrine is the fountain of youth. I took it for like three days, a thousand milligrams, and if I didn't jump off a cliff, Tacey would have killed me. and everyone around me would have killed me I saw it in the trash

Yeah that was That was that did not work for me Now can I do Toreen and a little Energy drink from now and again? Yeah but even I think even the Celsius Are making me goofy Hmm But I felt I didn't do Celsius

And I didn't do Modafinia yesterday You know I have narcolepsy And then I felt like I had the flu And I was dying But I actually And then I slept 10 hours last night But she probably needed it, though. Yeah, no shit.

I think I had something, though, because you felt tired yesterday. Carissa was over yesterday. She felt tired. You know, and a bunch of people around us felt that way. So I think maybe we may have actually had something. I don't know. Who the hell knows? Who the hell knows?

Okay, before we go, Scott, you have something, a question from the fluid family in the waiting room. That's right. Donabelle. Don a bell. Oh, Donna Bell. She's asking. Ding, ding, ding, down a bell. I don't know.

When she comes, when she comes. Yeah, so a hospital breathing treatment goes through a nebulizing machine, and it looks like smoke. Correct. Is that the same mechanics of using weed through a bong? Is that being nebulized? That is a fantastic question. Good question. So the way the nebulizer works in the hospital is.

is that you take a solution of whatever the medicine is. Usually it's albuterol, which is a bronchodilator. It's something when it hits the cells in the lung, cause them to contract. It opens up the airways. They will sometimes put another medication called Ipetropium bromide in there, which will decrease mucus production and do some other things. or you could put morphine in there.

Sometimes we'll put morphine in the nebulizer. But you put it in the machine, and then it actually aerosolizes. It's a very small aerosol. And you can do ultrasound nebulize. It's even smaller particles, but it makes a mist. And the mist, you inhale it. And then she noticed that most of the medicine goes out into, the atmosphere.

You only get drug when you're inhaling. Gotcha. Now, they've got new nebulizers that, for whatever reason, never really seemed to hit the market where it would only inject the medicine when you were inhaling, so you weren't wasting medicine. It seems like a great idea. It makes sense, doesn't it? Anyway.

So that's that. Now, the way a bong works is very different than that. A bong just uses the water to cool and filter out a little bit of shit. So the pathway of that is you put whatever the substance is that you're going to burn or inhale. It could be tobacco, and it's a hookah or pot, and we call it a bong. And you light it on fire. and then the smoke is now drawn through because you're inhaling through the water,

bubbles through there is cooled and some water-soluble substances will be left behind and then the smoke travels up and into your lungs. So that is more of a filtration type of a system. And cooling too. A cooling and filtration type system, whereas the nebulizer is an actual aerosol, aerosol system where, you know, hopefully you get all the medicine at once,

and you can actually, you know, make one that does that, but it's got a lot of moving parts. Anyway, that's a great question. Great question, yeah. Thank you, Dr. Steve. And it does look like smoke, but it's not smoke. It's not products of combustion. It is actually just the stuff that's in there.

It's just nebulized. So it's more, it's closer to steam, but it's not steam either. it's really just a mist. It's like fog. Yep. Okay. All right. Any other questions from there?

Nope. They'll do her. We have one other one here about nasal allergies, which we're getting into fall allergy season, so I thought it would be. Hey, Dr. Steve. Hello. I've been listening for a while,

so my husband got me hooked on your show. Uh-oh. But calling for the first time. Thank you. So I'm a question about allergies. Okay. I'm a 38-year-old, and I have been a long-time allergy sufferer. you know, pretty much my whole life.

Basically, everything environmental that blooms in every season here where I live in Alabama. Preach it, sister, I'm the same. Dust mold, if it's got fur or some kind of dander, I'm allergic to it. I'm lucky on that. I'm not allergic to dogs or cats, so that's good. Started allergy shots last year, but I'm also taking over-the-counter meditations on bad days. And so bad days, if I have an attack, it's, you know, the sneezing, itchy, watery eyes, itchy face. And Benadryl is the only thing that gives me immediate relief, but it knocks me out even if I just take, like, a half.

And so I'm wondering if you knew of anything that might work just as powerfully as Benadryl, but doesn't make me fall asleep as soon as I take it. I appreciate you and Dr. Scott so much. Take care. Not you, though, Tase. She's sassy. She's sassy. I was looking for the old lady laughing. Oh, there she is.

All right. So a couple of things. Tacey, you had this problem recently and actually got benefit from the Navaj. So if you've got a, if you have a bunch of allergens in your nose, your nose will, the cells in your nose will, the cells in your nose will, explode these things called mast cells, and you get histamine release, which causes fluid to be

released from the nose as the blood vessels dilate and the loose junctions start to allow fluid, you know, ultra-filtrated serum to pass through, which we call snot. And it's trying to wash out

those allergens. So the nose can do that. Or you can do it for it. So if you got a Navage, go to Dr. Steve.com and just scroll down. You'll see one on there. You can get it from there or you can buy it at your local CVS. And when times are bad, put the saline pot in there, used distilled water only. Wash all those allergens out. It's less for the body to do. You know, you can have a big abscess on your arm and the body will eventually take care of it. or we can lance the abscess, open it up, get all that shit out of there,

and take some of the burden off of the body of having to do all the work. Well, she mentioned only OTC medicine. Correct. She did not mention prescription medications. That's correct. So let's talk about the OTC medications that she could use that are non-drowsy. You got a couple of them in mind days? I mean Allegra D.

Correct. If the D part doesn't make her nut so. Oh, very good. I'm going to give you, you know what? You're learning the couching of the advice so that we don't get sued. Give myself a bell. So correct. You take these things if there's no contraindication to them.

That is correct. So, yeah, Allegra is fexophenidine. You can get the generic version at CVS or Walgreens or basically anywhere. 180 milligrams will last 24 hours. It's non-drowsy. And the nasal sprays are very good. Yep. And then there's also Monty Loucast

I knew I knew old Monty Luke cast He was a He was a card shark Don't you know Lots of medicines out there And the shots I did the shots for a long time

And they really did help me Yeah Yeah the shot If you will do the shots They will help As long as they identified The correct It's a giant pain in the butt though

If they missed an antigen It'll only help a little bit And then you've got to go back And get retested Yeah, so when Tacey mentioned the nasal sprays are a couple. One, if you don't want to carry your navage around with you, you can just get simply saline. It is an aerosolized saline. And I stand over the John because I don't want the, you know, mucus going into the sink so much.

And I'll spray this stuff. I put my head down, spray straight up into my nose, and it's saline so you can sniff it back and it won't cause any irritation. and then I'll spray both sides, let it kind of drain out, sit there for a second, then I'll blow my nose, so you get a big giant glob of disgusting mucous. And that will help a lot, too, if you don't do the navage. And then the other nasal sprays are the over-the-counter steroid nasal sprays, Flonase and the like. And you can buy those.

There are store brands, and you can get them relatively inexpensive. Don't fall for the aphrine allure. Afrin is great for one or two days. That's oxymetazylene. If you have nasal congestion, congestion, that's stuffed up nose. It'll open you up. But if you use it day after day after day, you'll get addicted to it. My ex-wife...

Your current wife got addicted to it as well. Really? Well, but it wasn't as funny because my ex-wife, who at the time I was really having a lot of problems, with. It was always fun seeing her walk around with this bottle of Afrin having to spray every 15 minutes to keep things going. That's how addicted to it she was.

So you have to take your little pleasures where you can get them. That's all I can say. But so yeah, so be careful with that. But pseudafed or phenyl aphrine or the other things

that they use in the D formulations can really help. But there adverse effects from those including, you know, fast heartbeat high blood pressure, stuff like that. So just make sure there's no contraindications to that. Okay. Hey. Okay. All right. The simple herbal nasal spray. Oh, shoot.

Oh, why didn't... Oh, okay, okay. Okay, okay. I don't remember... You see? You see? You're stupid minds. I don't remember the last time... He's a fucking idiot. I don't remember the last... He's a fucking idiot. Last time the Navaj got came up here when it was 100 degrees and sad.

You are one pathetic. loser. Uh-huh. Sorry. But you get nothing. All right. Yeah, that was an error of omission, not my part. And not just because Scott's my partner, that stuff is awesome.

And you can carry it around with you. Yep. The CBD version, I think, is probably better for home use. But you could, it just depends on your tolerance for CBD. It really helps me sleep, so I don't think I would do it during the day, but the regular just simply Herbal's nasal spray is amazing. Pretty good stuff, yeah. Yeah, it is.

And you just put it in your pocket. Yep. Yep. All right. All right, guys. Thank you. All right. What else you got?

Nothing. That's it. All right. Well, thanks to everyone who's made this show happen over the years. Listen to our Sirius XM show on the Faction Talk channel. Sirius XM Channel 103, Saturdays at 7 p.m. Eastern, Sunday at 6 p.m. Eastern on demand and other times at Jim McClure's pleasure. We're coming up to a year without, without a year.

a contract, don't say anything. I don't know what's going on. We're just flying under the radar, as we always have. It's totally fine. Go to our website at Dr. Steve.com for schedules, podcast, other crap. Until next time, check your stupid nuts for lumps. Quit smoking, get off your asses, get some exercise. We'll see you in one week for the next edition of Weird Medicine.

Thanks, everybody. Thank you.