Weird Medicine: The Podcast - 589 - Physician, Heal Thy Taint!

Episode Date: May 2, 2024

Dr Steve, and crew discuss: getting old stinks rhabdomyolysis acute kidney injury (sent home with baking soda) testosterone and testosterone "boosters" weight loss drugs Huntington Chorea and Parkinson Disease pseudoephedrine what's your BMI if you've had your legs removed? nasal steroids Please visit: simplyherbals.net/cbd-sinus-rinse (the best he's ever made. Seriously.) RIGHT NOW GET A NEW DISCOUNT ON THE ROADIE 3 ROBOTIC TUNER! roadie.doctorsteve.com (the greatest gift for a guitarist or bassist! The robotic tuner!) see it here: stuff.doctorsteve.com/#roadie Also don't forget: Cameo.com/weirdmedicine (Book your old pal right now because he's cheap! "FLUID!") shoutout1.com/weirdmedicine (either one works!) Keep Dr Steve in Ham Radio! Send a TIP here! Most importantly! CHECK US OUT ON PATREON!  ALL NEW CONTENT! Robert Kelly, Mark Normand, Jim Norton, Gregg Hughes, Anthony Cumia, Joe DeRosa, Pete Davidson, Geno Bisconte, Cassie Black ("Safe Slut"). Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices

Your show is better when you had medical questions. AIDS. Can you please stop bullshitting and get to the question? Get your hand off my penis! If you just read the bio for Dr. Steve, host of Weird Medicine on Sirius XM103, and made popular by two really comedy shows, Opie and Anthony and Benz, you would have thought that this guy was a bit of, you know, a clown. Why can't you give me the respect?

That I'm entitled to! I've got diphtheria crushing my esophagus. I've got Tobolivide stripping from my nose. I've got the leprosy of the heartbells, exacerbating my imbettable woes. I want to take my brain out and blast it with the wave, an ultrasonic, egographic, and a pulsating shave.

I want a magic pill. All my ailments, the health equivalent is citizen cane. And if I don't get it now in the tablet, I think I'm doomed, then I'll have to go insane. I want to requiem. my disease. So I'm Beijing, Dr. Steve. Dr. Steve.

From the world famous Cardiff Electric Network Studios in beautiful downtown, Tuky City, it's weird medicine. The first and still only uncensored medical show in the history broadcast radio, now a podcast. I'm Dr. Steve with my little pal, Dr. Scott, the traditional Chinese medicine provider. It gives me street cred with the whack alternative medicine assholes. This is a show for, does I say hello, Dr. Scott? Say hello. Hey, go ahead.

This is a show for people who never listen to a medical show on the radio or the internet. If you have a question, you're embarrassed to take to your regular medical provider. If you can't find an answer anywhere else, give us a call. 347-7-6-6-4-3-23. That's 347. Pooh-Hid. Follow us on Twitter at Weird Medicine or at Dr. Scott WM. Visit our website at Dr.steve.com for podcast, medical news and stuff you can buy.

Most importantly, we are not your medical providers. Take everything you hear with a grain of salt and act on anything you hear on this show. without talking over with a health care provider. I got distracted because I saw a super chat go by from the fluid family. Thank you. That's from Carl's Frosted Tips. Oh, I know Carl's Frosted Tips. He or she, they are on every show.

Good. Come back to WATP more often, F. Stut Joe. Okay, well, thank you, my friend. I feel like I'm a drag on WATP. As a matter of fact, I told Carl this time, and I don't know how I'm going to feel, but I just don't, with what's going on with me, you know, health-wise, we'll talk about it in a minute. I don't just feel real funny. And so I said, you know, if you want me to be Ted Williams, you know,

Ted Williams is the golden voice from the Detroit show. If you want me to be Ted Williams, I'd be happy to do that. And that way I don't have to try to spontaneously be funny. It was really hard for me to try to be funny in Detroit. when I thought my friends who had just disappeared, you know, from the show, I thought they were lying dead on the street in a ditch and, you know, their car had been stolen, their cell phones and been, you know, jacked. And it was really hard for me to try to be funny.

And it's really hard when you feel like I do right now. So I'm, we'll see if I can turn this thing around after a week of clean living in the mountains next week. we'll see, maybe I'll do something. But anyway, but yeah, thanks, Carl's Frost and tips. I appreciate the sentiment. I just feel like I'm always just a drag on Carl's show. And I feel bad. And it's kind of a bit now where he says, you know, Dr. Steve's on our show.

And then I get all these texts, I'm sorry, I sucked. I'm sorry. It's like, okay, well, then let's stop the cycle then. But I love, listen, I love those guys. It's my favorite show. It's like the Reader's Digest of all the Longhouse out there. I don't have to listen to certain shows. I can just listen to Carl's show because he does it better than anybody.

And so, and I enjoy it. And he's an actual friend. He and his wife are actual friends. And producer Chris and Kaylee and Andy and all the other, you know, people who are regulars on that show. I love those people. And I've hung out with them. And I'm going to hang out with them. in March 22nd in Largo, Florida.

I'll be at the VIP meet and greet, not because I'm a VIP, but because I made the lanyards for the VIP thing, so I will be there, giving out weird medicine merchandise, and we'll see, maybe I'll, you know, if he finds me something really

that I can be funny at, I'll do it. Anyway, don't forget the Amazon affiliate stinks. Stop using stuff. Well, no, don't stop using stuff. Dr. Steve.com. There's still stuff there. but it's the ROTI

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CBD nasal spray that we're going to be talking about a lot today. And patreon.com slash weird medicine doing some live streams there.

I'm putting all the normal world stuff there and I might put the outtakes so you can see sort of behind-the-scenes stuff on Patreon

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and if you want me to say fluid to you mama oh we got to do one today you and I do as soon as this is over we'll do it in about two seconds after the show is over

cameo.com slash weird medicine. Check out Dr. Scott's website at simplyerbils.net. That's simplyerbils.net. And, yeah, what else? Is that it? Okay. Very good. Check out Dr. Scott's website. Simplyerbils.net. He has the best CBD nasal spray on the market. Actually, someone called in and said that they bought, they found another CBD nasal spray. No, no. And they bought it and it sucked. Oh, good. So there you go. Doesn't surprise me, yes. You've got to win.

Myself a bell. All right. Dr. Scott gets nothing for being on the show other than plugs for simply Herbils.com. In a good time. It's just a plug. It's not an ad. So a couple of things.

Last time I talked, did I talk about my health bullshit? Okay. A little bit. So I got my, so I went on clean living. Not drinking. No, I wasn't drinking. You weren't drinking much anyway. You know, it's like I'm not sober because I was never not sober.

And I know everybody, every alcoholic said, well, I'm not an alcoholic, but I either drink or I don't. Now, I have been known in the past to do a little binge drinking. It's usually the first day I'm on vacation. I'm on vacation. So like people, was it DabbleCon or what was it when the isotopes played? We were up in Rochester. I think it was the creep off road. Okay.

I was the guy at the beer place. Oh, no. They played an outdoor concert at this beer garden, and I was the guy standing in front of, you know, the stage screaming, you know, M.F at the top of my lungs. That was the first time I ever met our buddy Sean, who has been here in the studio. Yes. I'm sure he was very impressed with meeting me. But anyway. So, yeah.

So, but, yes, despite all of that, I really don't drink that much. And so I just said, it's not doing me any good. So I'm just not drinking right now. And, you know, I've gone years before without drinking. And so that actually, I think, I don't know if that's what it was, but my liver enzymes came down. So that's good. Yay. All right.

So I went off my low sarton. And kids don't do this at home. I did this in concert with my liver. my primary care provider. And I went off my low sartin, which is an angiotensin receptor blocker for blood pressure. And lo and behold, my creatin went back to normal. So I'm no longer in renal failure. That's great news.

Can you like shut up? All right, all right. I hit the wrong butt. You're two for two. Now, let me see what else was messed up. Oh, so liver. And my blood glucose, well, I, I. I didn't do it fasting.

I ate an apple before, so it was slightly elevated, but I'm not too worried about it. So everything actually was back to normal except my creatine phosphokinase, CPK, which is an indicator of muscle damage. So the reason that these things work is that muscles have this enzyme in them. Okay. Cretine phosphokinase. And what it does is it moves phosphorus on a creatine molecule, hence the name, phosphokinase, you know, kinase meaning moving. And so it can move, it moves phosphorus around or does some bullshit.

I don't know what the hell it does, but it is intrinsic in muscles. It's very nice. Heart and skeletal muscle. And when the muscle tissue dies, it will release all. of its enzymes, but you can detect the ones that are specific to that. So you'll have an increase in CPK. You'll have an increase in other stuff, too, that they release, like potassium and, you know, maybe a little hydrogen, some, you know, DNA sort of byproducts and stuff like that.

But we can detect the CPK, and so we're detecting that. And it's still going up. Now, I fell six weeks ago. I'm still hurting in exactly the same place that I landed on. So I've got a guy looking into an indolent. Rabdomyalysis. So what that is, is indolent, just meaning it's smoldering. But, and I asked him, he's a physical medicine rehab specialist.

It sounds like he runs a nursing home, but that's not right. That is an actual medical subspecialty is physical medicine rehab. They're also called physiatry. They need an ology name, and people would not get so freaked out. You send somebody, well, I'm going to send you to a physical medicine rehab specialist. I ain't going to no nursing home. That's right. So anyway, they, so I emailed him and just said, have you ever heard of this where someone's injured?

And then six weeks later, their CPK is elevated because it's like a delayed sort of destruction of the tissue or whatever. And he said, yes, I'll get back to you later. And I haven't heard from him since. But that's the only thing. So I can live with that. I think we can, that's probably something we can think. You don't think it's, you don't think it's a side effect from. The statins...

Well, I'm not having been on a statin in two weeks now. Yeah, but I'll say that may not be enough time for them to stop. Oh, maybe. And that would be my only thing, too. But why is it going up now? That's the thing. But, you know, maybe. Maybe.

Yeah. Yeah, that's interesting, isn't it? Because typically you'll see that after a pretty severe injury car wrecks and people getting falling off of houses. But you see it going up to like 4,000 or 40,000. Mine's like 280, 230, but it's going. It's going up, but it's just indolent, you know, it's just smoldering. So it's just weird. I can't sleep at night because I've got this pain wakes me up, but it's in my muscles,

but it's not in an anatomic place that I'm used to having, you know, detecting pain in people. I mean, I do shoulder injections every day in my practice, and this is not associated with any specific anatomic structure that I'm aware of. And that's a good point real quick to talk about. Anytime anyone comes into us with any kind of pain. Yeah. We liked it. We liked, and we liked, we liked, we like for people to tell us what we want to hear. You know, they tell us something we poke on it.

And they're like, ow, it hurts right there. We're like, good, that's a burst of, you know, like, maybe a hip burstitis. Or like you're talking about, maybe a shoulder, specifically, you can have a shoulder rotator cuff or a long head of your, you know, biceps tendonitis or whatever. But, you know, when somebody tells us something that's not specific, it's kind of global. Yep. And diffuse and spread out. You start thinking, well, that's a little bit different.

Yeah. You know, and then you do start thinking muscle injury, muscle tissue, right, waste product, and, you know, kind of systemic inflammatory stuff. Well, I'm going to blame COVID. Yeah. I'll blame the vaccine and I'll, well, sorry YouTube. The vaccine is obviously effective. It can be any kind of, you know, illness.

But I'm blaming something. Something ain't right. Falling down and going boom. Well, that could have. Let's just stick with a going, falling down and going boom. Usually that will cause a spike in CPK that goes up quickly and then comes down rather quickly. You know, but it's been like, I think it was six weeks ago, right? That's been a long time, yeah.

It's been a while. But anyway, interesting. But now I'm going to get off all my supplements, too. Maybe it's one of the supplements. And it could be phosphatil syrin. Who the hell knows? Could be. You know, so I'm getting off everything.

Torrene and all the good stuff. Clean, well, the taurine's a hard one. I like drinking my energy drink in the morning. Yeah. But, you know, I guess I'm going to have to forego it. Sure. to God, I can drink tea. I mean, I can't take Tylenol

because my liver enzymes were elevated. I can't take non-stroyal anti-inflammatory drugs because my kidneys were effed up for a while. And so, you know, what am I supposed to take? I'm taking palmettoil ethanolamide. Well, now I've got

to look that up and see if that can cause this. Hey, let me ask you real quick, because what's your telling me is. By the way, palmetoyle ethanolide, non-narcotic, non-steroid, non-steroidal, with decent data for pain, both acute and chronic. So I'm doing a lot of research on it right now in the medical literature, because I think we're going to start, you know, prescribing it to some more of patients. Yeah, that would be good.

Palmetoyle, ethanolamide. It's also just called P-E-A. P-E-A, got you. But anyway, go ahead. Yeah, I was going to ask real quick, you know, because I'm pretty, you know, I'm really impressed. by your labs correcting so quickly. I'm not fucking around. Well, that's what I was going to say.

But, you know, it's really amazing. Because when did you have the initial labs that got you kind of concerned? Well, it was 10 days ago. See, that's what I was going to say. I mean, you've done extremely well just in a week's time. Well, hydrating, getting off the medicines that were killing me. Lots of good loving? No.

Oh, you mean, okay, so we'll just, we'll stick with the, we'll stick with the hydration and the exercise. Just ruin my day. We'll stick with the hydration Okay But I'm Oh, I did my third thing for normal world Check that out I'll let you all know when they are

And if you're a member of our Patreon I will post the links directly there As soon as they come out With the timestamp Already all built in All you have to do is look at it But the first one is already on our Patreon That was the worst way to die

Which spoiler alert is Fornier Gangrene The second one was on A lady that had nostril bigger than the other. And I said it was either co-anal atresia or just a deviated septum. And then the third one is on vapor lock, aka penis captiva. So that should be out soon. But it's been fun sort of getting to do my TV degree again because, you know, my original

degree was in television directing. But digital video is kind of blowing my mind because there's so many parameters. You know, how the color depth, how many, you know, I have to shoot in this thing called 422 format. And to me, it looks like shit. I would never publish it in that form. It just looks all gray and crummy. But they say that's what they want. And then they can take it and manipulate it with their, you know, software.

And, you know, it's a professional television studio. And they do something to it to make it right. and it's got enough bits of information there that they can, you know, tweak it. Wow. Yeah, it's pretty interesting. Yeah, it was really. You know, back then we just turned the damn camera out. Let her all make sure that there's some light.

Yeah, get the aperture. Yeah, get the aperture good to get the light right. Yep, make sure the light's good. And we had some fixed aperture cameras back then when I was doing this and when I was actually in school, and you had to turn your lights up and down to get what you wanted. you couldn't adjust the aperture of the camera. How well is that? Crazy.

Anyway, lots of things have changed. All right. Well, you want to just answer some questions? Yeah, we'll do some questions. Let's do that. Number one thing. Don't take advice from some asshole on the radio. All right.

What do we want to do here? Okay, we've got this one. Let me see. Okay, let's try this. I don't know what these are. Hi, Dr. Steve. Hello. I currently, well, I was in a house.

was A.K.I. Acute kidney injury. What that means, they would detect that by doing some blood work. And normally what you're looking at is a molecule called creatin. And creatinin is very efficiently filtered out by the kidneys. So when the kidneys are injured and they're not filtering that, well, they might still make urine. You might never notice it. but the creatinine will start to rise because it's not no longer filtering efficiently. So that's right.

And they sent me home with sodium bicarbonate, which is just baking powder. Right. It's baking soda. That's right. Not baking powder. No. Baking powder actually is a leavening agent. Baking soda is sodium bicarbonate.

And it's a strong base, and what they're trying to do is alkaline or alkalize your urine. Go ahead. And baking soda or alkaliseltic. and also Valtasa can you tell me how those two things are going to help me

I saw Veltasa said that it binds potassium in your gut right okay I mean binding to potassium how are they going to help and also I can't take

it within three hours of pills so I have to take it my morning medication wait three hours take the Valtasa and wait another three hours before I can take my afternoon pills

Yeah. Anyway, and now it says CKD. Right. If you know what that means. I do. Can you tell me, please? Yes. I don't know.

All right, thanks. Bye. Now, okay, first off, he was admitted with acute kidney injury, diagnosed with KD, which is chronic kidney disease, and just, hey, here, take these pills. Yep. See you next time. Yeah. Good luck, buddy.

How about? You fuck right off. You have got to do it. Now, I don't know the situation. It may absolutely be that they told him all this stuff, but the whole kidney failure was just banging around in his head. He couldn't hear anything else. He might have felt really ill.

Yeah, or just stressed out by that. Or they just gave him a shit and said, good luck, buddy. Or that. And I see too much of that. Yeah, I do too. So I'm not going to go too far into what Veltasa is. When you have kidney failure, you can end up with a high potassium. Okay.

And when you end up with a high potassium, that can affect your heart in a very negative way. And if you look at the EKG for the medical students and residents out there, you'll see a high-peaked T-wave on the EKG. They'll know what that is. But the way I would think about that is that you are storing loads of potassium under that T wave. Okay. That's what would make it. That's how you would remember. It's a good visual, yeah.

You just have to have it. But anyway, Veltasa is this stuff called peteromer, and it binds potassium in the gut. Okay. If it binds it in the gut, then you can't absorb it into the blood. And if you can't absorb it into the blood, then you're just going to shit it out. And it will not be, it will. not contribute to your hypercalemia or high potassium in your bloodstream. And so anyway, you know, it's chronic kidney disease is basically the number one reason

that they do that. There are some other medications that can cause high potassium, and one of those is a drug that I just got off of, which was Losartin or ACE inhibitors, like capypril or lysinepril. They can increase potassium as well. Sometimes when you're getting good results from the blood pressure and their kidney function is otherwise, you know, okay, but they've got sort of this exaggerated high potassium effect, then you can throw this kind of stuff out. Gotcha. And what's nice about it is this stuff is not absorbed by your body to a significant degree, and it just absorbs the stuff and then you just shit it out. Now, the reason that he can't take his other medication while this stuff is in his stomach is because it will also absorb some of those, particularly those that are potassium salts.

Gotcha. Right. Yeah. So, you know, it'll reduce their availability because it's binding that too. Right. So that's why you're going to have to. And little parlor is the availability of this thing, too. You know, you would think of the potassium medicine.

Well, that's what I'm saying. Yeah, yeah, yeah. No, that's what I'm saying. Okay, I'm sorry. He can't, he was saying one of the things he was complaining about was he can't take him with food. Can't take this with his other medicine. Yep, yep. You know, then we had a question.

Because it's going to, it may absorb some of those other medicines and prevent him from absorbing the good stuff. Gotcha. So he's got to wait until the peteromers out of his stomach. You know, we had a call last week about this. You know, why is it you can't take certain medicines with. Well, there's a good example. There you go. Perfect.

Perfect. There you go. There you go. Perfect. I got your hand on my penis. Dr. Scott. I love it. I do love that.

It's the greatest thing. If you all don't know where that comes from, we talked about it a few shows back, just go to YouTube and Google, get your hands off my penis. I think it will come off. If it doesn't email me, I'll say, you're like, it's one of the greatest. If I was ever going to be arrested, that's how I want to be. Oh, you know your judo well, sir. All right. Sorry.

Let's try this one. Hey, Dr. Steve. Got a question for you for the podcast. Have a testosterone question. Currently taking the andro gel. And I just wondering if it would be okay to take a testosterone booster pill like you would find at a health food store. If that would help to get the old numbers up, my number. are running really low, like, pretty much on zero.

So I've got high blood pressure. I use pills for that, and that's about it. Let me know what you think. I wonder why his numbers are zero. I see people with low testosterone all the time. It's very rarely zero and less. Well, you know what I'm going to say. Unless they were juicing before.

Yeah. And they literally juice so much that their body is making zero. Well, their testicles just shut down. I've seen this. Now, I'm not accusing him of anything. I'm just saying, I've seen this before. So I just wonder if that was why. But if you're juicing, and I'm not, listen, it doesn't doom you to it.

But the people, I'm just saying, the people I have seen with zero testosterone, I mean, literally you do a blood test, it comes back zero. We're people who were juicing. And what happens is your testicles are, you know, they respect. to a signal from the pituitary gland that says your testosterone's a little low, make some more. Yep. And so it secretes follicle stimulating hormone and leutinizing hormone, and the testicles go, okay, well, let's make a little bit more. And then when it gets up to a certain level, then the pituitary stop sending that signal is heavy. So it comes back down.

It's always going between two levels, sort of undulating. The body does this all the time with these feedback loops. and it's a way to just keep these hormones at a certain level in the body. Now, when you start juicing, for example, or if you take an overdose of testosterone, when you already are making testosterone, the pituitary goes, whoa, whoa, whoa, whoa, whoa, there's too much in here, and it stops producing follicle-stimulating hormone and lutenizing hormone.

And then the other thing that happens is, the testicles go, well, there's plenty of testosterone around here. We can take a hand. Or just take a break. What are we? Why are we working so hard? And when you stop taking the testosterone every once in a while, your body just won't start making it again. So I don't see the point in this person taking a testosterone booster.

If his testicles are already not making testosterone, there are other tissues in the body that can participate in that. but no point in doing it. His testicles have stopped functioning. They are deceased. They are no more. Goodbye. Right? Yep.

So what he needs to do is take his testosterone supplement and bring it back to normal and keep it there. Now, normal, I don't know how old he was. He sounded pretty young. He sounds young, yeah. Could be higher than what some primary care people are willing to treat. Right. The urologists say primary care under-treats. says they'll treat people up to about a level of 300 and when it should be 800.

Yeah. So if you're having issues that way where you're being maintained in the low normal and you still don't feel well. And you don't have any other risk factors. You might want to see a men's health person that's a little bit more into getting the doses right. Maybe a little more aggressive. And I may make a suggestion too.

Yeah, of course. In my experience, personal experience and I have heard others say the same thing, the The andro gel was not as effective as a shot, as an intramuscular shot. I keep hearing this, and I tried the shots, and I didn't find that to be the case. You know, I was saying certain people respond. You're right. And I tried the Andrew gel for, and, you know, I think we've talked about it before. My testosterone was 45, which is, you know, talking about getting close to zero.

And I never took any kind of anabolic steroids. I never did any kind of juicing. But for some odd reason, I just had a really profoundly low natural testosterone. level and the well you were wearing that damn cup and yeah that's right it's right it made my well plus i think my ex-wife probably made my oh she chopped your balls off yeah they were they were deceased too and you of course you know her so that makes sense to you but um but anyway so yeah so i tried the jail man you are one pathetic loser i tried i tried the jail yeah i tried the jail for a little And I just got nothing from it.

Nothing. My levels never changed. And I never felt any better. My sleep was still awful and I still couldn't make any, I had no strength. Yeah. Muscular strength. So my primary, Doc, who, he and I talked about, and heck, let's just try the shots. So now I do a, I do a shot every other week.

Cheaper, too. Heck, yeah. It's a lot cheaper. And it's just, and honestly, it's a little more convenient. We had that men's health guy on here a long, long time ago that was advocating to have a cyclic, you know, testosterone. Because the thing is, when you give yourself a shot, you get a peek, and then you get a trough, and it's like a sine wave, and then you give yourself a shot again.

You get a peek and a trough and a peak and a trough. And my argument with him is that that's not really physiologic. Our testosterone levels are pretty constant. Right. But he said, no, no, no, it's more physiologic. I didn't argue with him, but I didn't understand that. So I know it undulates, but it undulates when you do the, The androgel, too, you get a big dose in the morning when you put it on.

And then about four hours later, it's all absorbed and it goes back down again. Yeah, I don't know. I kind of lean with him because to me, I feel a lot more normal with that spike. I'm almost liking it to a female menstrual cycle, you know, where you feel pretty good for a week or two, and then you don't feel so good for a week or two. And I think that's kind of maybe how. Men don't. Well, but we have the cyclical that way.

But we have a cycle kind of like that. You know, the benefit to the females is that, you know, when they actually have the physical bleeding, they know when they're going through that cycle. That's ketchup of my french fries, if you know what I mean. And we don't know when we're going through it. So we have those weird, you know, emotional mental cycles as well. So that's, but, you know, I'm having my period. I'm having my period, damn. But you just, you just, you just can't see it.

Yeah. But, you know, the other half of his question was about like an over-the-counter testosterone supplement, adding that to the enderogel, which is... There's no point in that if his testicle... The supplements are intended to cause your testicles to... Right, right. Now, if he wants fertility, if he wants to try something, he could go to a fertility specialist, and they could put him on clomophine citrate.

Now, clomophine citrate attempts to stimulate the testicles to make testosterone again. So you're making your own testosterone. your testicles don't shrink and you continue to produce sperm whereas if you use testosterone replacement your testicles will shrink because they get lazy

and they'll atrophy and you'll stop producing sperm too don't really need them anymore some of us don't but some people may I'd go say younger people one times the clomophine is more appropriate but you know I just thought

one of the time that you'll see literally a testosterone ground to zero, is prostate cancers. Well, yeah, of course. Well, I mean, but not everybody knows that. Oh, okay. Because people, they'll give. They're giving the medicine to make their...

It's called a chemical castration. Chemical castration, yep. Yeah, they give them lupron and things like that. So, yes, that's correct. Yeah. All right. All right, well, good luck, buddy. Yep, let us know.

All right. Let's see. You want to do a blind voice mail? Let's go. Let's give a shot. All right. This one says testosterone. Okay.

Okay, here you go. Let's try this one. Hey, Dr. Steve, I had a question. I can send it via text, too. Okay, this is why we don't do. Oh, no. Okay, yes, you can send a text if you want to. Let's see here.

Okay, wait, he called back, so here we go. Hey, Dr. Steve, I was comparing Manjaro versus Trulicity. Yeah. I was on Trulicity, didn't have any issues, but they couldn't get it in stock. So I want to know the difference between the two ingredients. Yeah, sure. Thank you. Okay.

Well, Manjero is terseppatide, if I remember correctly, in Trulicity, is Dula Glutide. And so they're different. The Dula Glutide has a single action. It mimics this hormone GLP1. Manjaro is dual action. It mimics GLP1 and GIP. So Manjaro has been found to be somewhat more effective in most people when it comes to weight loss. And that's why it is difficult to get your hands on sometimes.

Gotcha. It's also more effective than the other one at supporting weight loss and blood sugar. But the trulicity will lead to less feelings of nausea. But some of these things work by causing your stomach to feel full. I know I took the Ozampic, what's that, semi-glutide. I just tried it. I wanted to try it because so many people are talking about it. And plus I've got 20 pounds I'd like to lose.

and I it absolutely made me feel like I had a stomach bug oh no so I lost eight pounds crampy kind of no not crampy just nauseated okay gotcha stomach felt full when you ate you had to pay attention to feeling full don't eat past that because it make you sick

and I lost eight pounds right off the bat and then I got off of it I didn't go back because I just wanted to try it gained her right back Not thinking I was eating any more than I was. You know, I eat pretty good. You know, the other day, I had just a Caesar salad and some sweet potato fries for lunch and then had salmon for dinner. And I still gain weight.

So, you know. So anyway. Yeah, so there you go. So it's, that's what, that's kind of how they seem to work. And I have this one of my female partners lost 40 pounds. on the semi-glutide, but she just feels sick all the time. But she looks amazing. She looks unbelievably great.

Now, Tacey wants to lose weight for Liam's wedding. Okay. And she wants to be back to her ideal body weight, which when she's at her ideal body weight, she's looking pretty good. But it's like, boy, you have no interest in losing it for your husband or to live longer. You just don't want people at the... a wedding going, oh, look at her, you know. Nope.

Oh, is that Liam's mom? Have they picked a day? Oh, yeah. Oh, they have? Yeah. It's in August of 2025. Gotcha. So, yes, the little boy that did the Ashley Madison commercial.

The greatest Ashley Madison commercial ever, that's right. Okay. That was a good one. So anyway, you can lose weight on both of them. Right on. All right. Let's see here. Okay. Let's see. Well, dang it.

Hello, Dr. Steve. I'm a huge fan. That's another blind phone call. I was just wondering if you can maybe elaborate. I have a friend here who suffers from Huntington's Korea disease. And from my understanding, he's losing control of his motor function. Right. And I was just wondering if maybe you can help me distinguish the difference between Huntington's disease and Parkinson's, because I know that they're similar, They start to lose control of their motor functions.

Yeah. And as I understand it, Huntington's is a genetic disease with no cure, only treatment. I appreciate your time. Thank you very much. Yeah. Love you, love your show. Hey, man. Love you, too.

Yeah, both of these are motion type disorders. Huntington's disease what Woody Guthrie hit. Right. And we don't screen. Okay, I got in trouble saying. that we don't screen for this on this show. What I meant by that is we don't screen the general public for it. Right.

We do screen the offspring of someone that has Huntington's to see if they are at risk or if they are at risk of passing it on to someone else or if they are at risk of getting it themselves because it is genetic and we can detect it. Huntington's disease attacks nerve cells in particular. of the brain, and these nerve cells gradually break down, but these attacks cells that control voluntary movement. Okay? So a lot of people don't know this, but your brain has these cycles just like the hormones

do, right? And there's these circuits, and they're flying, and they're flying, and they're flying. It's like having a flywheel. This just came to me. Okay. So if you've got a fly wheel and it's spinning, right? you can apply pressure to it and extract work from it, right? So you can put another wheel on it and it would spin the other way.

There's things that you can do, but this flywheel is always spinning. The brain has circuits like that. They're always spinning, but then it can apply countertension to those circuits so that you're not spinning your arms around all the time. but when you need to move your arm in that sort of motion, it disinhibits that circuit so that you can move your arm. And I don't know why it's that way. It seems like a crazy way to design the damn thing.

You would think that you would want it to be quiet, and then when you want to move, then it would turn on. Turn it all right. That's how we design things. But the brain isn't designed that way. The motion is there, and then you disinhibit the inhibitory circuit. which is a double negative to make the motion actually happen.

Right. Well, in Huntington's disease, you are killing the cells that disinhibit those movements. And so now you get this sort of cyclic, dance-like movement, and they cannot stop it. And they may move their fingers, their feet, their face, their torso. I've seen, you can just Google Korea form movement, but it tends to be cyclic and sort of undulating. you know, back and forth in a circle sort of movement. They usually appear in middle-aged

people. It's rare, but it can show up in kids and it tends to get worse over time. Mild clumsiness is how it starts and then it progresses from there. Makes it more difficult to walk and then you fall.

Uh-oh. You know. Yeah. So anyway. So, yeah, it's and again, it's inherited, passed from parent to child, through a mutation in a particular gene. And when you have Huntington's,

each child has a 50% chance of inheriting a copy of chromosome 4 that carries it. So it's, anyway, if they don't inherit the mutation, they will not develop the disease. They can't pass it on to future generations. And when it occurs without a family history, it's called sporadic. So sometimes someone just gets hit by a gamma

It changes chromosome four and it causes Huntington's. But anyway, so there you go. So that, now, Parkinson's disease, the cells that die are different. Those are in the striatina nigra of the brain. And what happens with those people as opposed to having these sort of fluid motions. They have just the opposite. They have very rigid movement, sometimes no movement at all. they can get

stiff, they can get extremely stiff. One of the ways that we'll diagnose it is if you hold on to someone's wrist and you flex

their elbow and extend it and flex it, it will ratchet. In other words, it'll kind of go dig-d-d-d-d-d-d- instead of a nice

smooth movement. And, yeah, they have other symptoms as well. And if you get dementia with that, which you can, if you have

Parkinson's long enough, it's generally a thing called Louie Body Dementia, which, you know, is associated with Parkinson-like symptoms. So anyway, so there's right now we don't have treatments that will reverse things like Huntington's disease. There's a drug called tetrabenazine that treats the Korea. And certain antipsychotic drugs can help control the hallucinations. in the Korea as well. I'm hoping that in the future,

we know what cells are dying. Right. And they, I'm trying to remember what they produce. Maybe it's something called Huntington. Huntington. That's what's called. It's a protein.

The gene is a protein called Huntington, obviously named after Huntington. And it's, it causes defects in the building blocks of DNA that repeat more times than I normally do and you just get a clogged up cell that's not working. And so we know the target.

We know how it's encoding this person incorrectly. So we should be able to, in theory, be able to stop this once you see it happening. So there's a couple of ways in the future that we could stop this. One would be just genetic engineering. Yep. The CRISPR stuff. They're starting to do it with sickle cell now. So, you know, going in and actually changing the person's genetics, it's a little bit harder

to do in the brain, you know, to go in there because those cells have already been formed when you're in embryo and they don't change. So you would have to have something like a viral vector, the virus that would go in and inject an improved version of the gene into those particular cells. But then do we want a virus just floating around in our brain infecting cells and stuff? So it's going to be a while before we have a genetic fix for this. But there may be a medication fix for sure that just says stop doing that. So hopefully that's...

Well, you know, and one thing they're doing with Parkinson's, and I don't know if they've looked into this with the hunting doesn't know, but they're doing the deep brain stimulators, and they're improving with those all the time, too. Right. Well, they've been doing that for a long time. I mean, I remember when I was a kid seeing them do a deep brain stimulator on television. Yeah.

Oh, I didn't know that. Yeah, they showed the actual thing. I was like eight or nine if I remember correctly. Yeah. But, you know, I think with the onset of all the computers and the supercomputers and certainly AI, they're going to do a better job of programming those deep brain stimulators, which I do think will help. Oh, yeah. Yeah, AI. It may not fix it, but what it does, it helps with the uncontrolled movements.

Yeah, deep brain stimulation first developed in 1952. Oh, my gosh. So I was starting to think I was crazy remembering this, but I do remember when they showed it on TV. Three or 24 Fuck off Well that's because you're an idiot That wasn't very nice was it Oh it wasn't very nice

All right Yes I am old Wow I'm going to die Yeah it's crazy Anyway Yep All right

I hope that helps Yeah good luck dude All right Okay this is the guy with acute kidney injury Called back Let's see We've got one from Kim In the

Okay, let me do this one and then remember that one because this one just came in. Dr. Steve, my name is Greg. I'm state New York. Yep. About 315 pounds, 52 years old, in good shape. Tried many, many different diets, have not succeeded. Are these weight loss injections worth to try? or is there any other solution for me?

Well, there's all kinds of solutions. The question is, why have those other things not worked? And they don't work for everybody. One of the things that they did, and we've talked about this study in the past that really, really big people, Brooklyn Blowhard size folks and others like that. And, you know, by the way,

Blowhard's doing very well, lost shitload of waste. great but it took a lot of effort to do and it's difficult but they you just say well just eat less well this is what they did they did and and overweight people including me apparently will say well I'm not eating that much I mean my mother-in-law will say well I only eat one meal of day and she's sincere about it and then you watch her and it's true the meal starts at seven in the morning and it goes until 11 o'clock at night. She's never not eating. And if you asked her, now she's admittedly, she's dumb, but you don't have to be dumb

to have this. But if you asked her how much that she ate to estimate how much she ate, she would grossly underestimate it. So what the question was, is this something built in or are they just bullshitting themselves? So what happened was they did this study using a thing called doubly labeled water. and what doubly labeled water is is really cool. You give it to someone, and when they piss it out, you can figure out how many calories they took in.

There's a method that they use, and they can determine how many calories you actually took in a day. Okay. And then they would give these people a diary and say, write down every single thing that goes in your mouth, in your big fat and craw. You're just shoveling down your gullet. Now, they give people these diaries, and they would write down everything that they were eating.

And when they compared the two, they could calculate how many calories that they documented versus how many calories they actually took in. It was off by 300%. If they estimated 1,000 calories, they were taken in 3,000. If they estimated 2,500, they were taking in 7,500 cases. And what they concluded was that there's a mechanism in those people's brain that makes that impossible for them to accurately gauge how much they're taking in. And that's the problem. So it really is something that can't easily be fixed because that's not easy to fix. No.

So, yeah, if the semaglutide or those types of medication, if you've really given everything else a proper trial. and you've done exercise and you've changed your lifestyle and you're not drinking because that's a lot of empty calories and you've done all these things. And I think it's okay to talk to your health care provider and say, could I try one of these things? And if they say, get out of here, I don't do that crazy stuff. You could at that point go to a weight loss clinic and just make sure it's a legit one that sends a note to your primary care. And it needs to be counseled or coupled with nutritional counseling as well as sometimes psychological counseling. Yes. That helps.

It helps. And I'm not saying you're crazy, but it is difficult and you can feel bad about yourself when you don't succeed right off the bat. But if having a medication that makes food gives you basically gastroporesis, in other words, slows down the transit of food from your stomach that makes you feel. feel full earlier and longer that causes you to eat less because you're kind of sick to your stomach. If that would help you, then yes. But just be aware. And I wish Tacey were here. This one of the few times I wish Tachie were here. Just kidding, Tacey. She'll hear this and get, I'll hear about it. No, she won't. Listen. But she will tell you that she's lost tons of weight on these things in the past and then gains it all back plus 10.

So what's the point? Well, then, are you supposed to take it forever then? I would like to not have to take something forever. But if you're going to really lose weight, you have to make a lifestyle change that lasts forever. Now, you can blow it out your ass every once in a while. You know, little skinny fuckers like, I don't know, well, like Diane, lady diagnosis, she can, she just eats one potato chip and she's satisfied. it's like you're a damn lunatic how can you do that oh i just eat one and i'm satisfied a bag lasts me

you know several weeks and i throw it away yeah see but i'm the same way i'm the same way i can eat just one bite of a of a of a of a cupcake one bite yeah and i put it up and i just walk off no i eat one bite of a cupcake and then i eat six of them that's the problem so uh yeah so that's hard to get to that for some people where they can do that. I cannot do that. So that means I have to eat low or, you know, things that don't have a lot of calories in them in the first place, which is unsatisfying. But, you know, celery or, you know, sugar-free jello and stuff like that.

And, you know, after a while, that's just unsatisfying. And then I get out the chocolate cheesecake and put a bunch of whipped cream on it and go crazy. So I'm just, you know. I got down from 200 down to about. 160 and then climb back up to 180 and I'm just kind of stuck there. Yeah, right on. Anyway, yeah. So, dude, if you can lose 30 pounds, you will improve your odds of sudden death by a

significant amount. A 10% weight loss is, and that's about what these things guarantee, but you can lose more than that. Yeah. Now, if everything else fails, you tried that, you've literally tried everything and nothing is working for you. Then bariatric surgery is an option. Yeah, the balloon, the balloon in the sleeve.

I mean, there are a couple different options. All kinds of things, but you want to talk to a bariatric surgeon, someone who does that, you know, primarily for a living. And they're going to have fewer adverse events. And you want to do the least changing of your anatomy that you can do and still have a good expectation of a good result. Especially if you can do something that's reversible. Yeah. Now, well, the gastroenterologist, you're right, have just this inflatable ball. Yeah.

And they shove it down your throat, you're out, with an endoscope, and then they blow it up in there, and it just makes you feel full all the time. And I don't know somebody that said that it's worked extremely well. Really? Extremely well. Now, you can defeat it. You can drink milkshakes like an MFer. Yep. And you'll have diarrhea because it'll be shunted into your small intestine too fast.

but I know people that just they got to have it. I agree. And then they're just, you know, sucking down milkshakes and all kinds of, you know, pudding and stuff and just defeating it. But that is an option. That's an option. There's all kinds of things. Yeah, go ahead. I was just going to say, we got another great question.

Yep. You ready for one? Yeah. From Kim, I heard the Sudafed doesn't work. What would you take instead for a cold? Yes, that was one of the ones that we wanted to answer. So I don't think it's pseudofed. I think what they determined didn't work was phenopropanolamine.

And that was the thing that they replaced Sudafed with in a lot of these sort of oral decongestants. Yeah, the ones that have multiple medicines in them. Right, right. Because Sudafed, now you have to sign a paper and you can make math out of it and all kinds of stuff. Plus it causes tachycardia and it can cause high blood pressure and stuff like that. For short-term nasal congestion, I just honestly like Afrin nasal spray. It is habit-forming. I am warning you now.

If you use it twice a day for five days, then you'll be using it twice a day for the rest of your life because you get rebound nasal congestion. But if you can just use it once a day or a half dose, you know, at bedtime when you go to bed and then get a nabage or a netty pot for the rest of the time that eucalyptus. Or a little, you know, simply herbal sinus spray. Yes, or simply urnol, or urinal, simply urinals, sinus spray may help. But, yeah, I think for just run-of-the-mill, short-term nasal congestion, you really can't beat over-the-counter, you know, oxymotazilin, 0.05 percent, I think, is the concentration. But anyway, okay, here's another one. Question for Dr. Steve just had surgery. Now can't feel the skin where the incision was made.

Will that come back? You want to take that one? I'll say sometimes it does. Sometimes it does. Can't they feel that? Well, because a lot of times when they make that big surgical incision, those nerves are damaged, sometimes beyond repair. They cut through peripheral nerves. They cut through the peripheral nerve.

Give it out of the brain. Cutaneous nerves. But what we typically see is the longer and the better the job is that you'll get a lot of the sensations back, but it may be a different kind of sensation. And peripheral nerves can grow back, but sometimes when there's a surgical wound with a scar, they will grow back. but they'll spin around themselves and call it a neurofibulary tangle or a neuroma. And neuroma sometimes can be really sensitive. I remember doing a skin surgery on somebody, and they developed a neuroma, and it was just, they would just touch it and phew, it would send electricity up to their brain.

So what I did was I numbed them up again, and I took out the neuroma, and then sewed them up again, and it didn't come back. But, you know, I'd rather be numb than have. have pain, but it can take anywhere from 12 weeks to two years for those peripheral nerves to grow back, but they may very well grow back. And typically, what you'll start seeing, you'll start seeing some pain because they start to grow back, you'll have some weird sensations. Well, have you ever let your foot go to sleep in the movie theater, and then when it comes back, you get that, those hyperalgesia is very, you know, where you get the pins and needles

and it's just like, oh, I touch my foot, and it just sends pain up to your brain. and then it goes away. Yep. It's really amazing. Human body is an amazing thing. Yep. When it gets screwed up, it can kiss my ass, which is right now where I am with my,

I have a love-hate relationship with my body right now. But anyway, all right, Dr. Scott, before we go, I understand you've got another question from the fluid family. Yeah, good. If you want to join the fluid family, by the way, uh, follow us on Twitter at Weird Medicine, and I'll usually announce it.

there, but also if you go to YouTube.com slash at Weird Medicine and just subscribe, then you'll get and sign up for notifications, then it'll notify you when we go live. It's usually Saturday at 1. Today we're Wednesday at 6, so, you know, what the hell? Yeah. Anyway, what's the question? Yes, so the great diesel child, he says, I've got a question, was inspired by seeing this superjack guy that was in a wheelchair. He's a double upper leg amputee, and he was doing pull-ups, and he was just,

just a beast. Yeah. So my question is, do guys that are double amputees need to modify their diets to make up for less body mass? Oh, well, that's an interesting one. Now, weight-based medications very often, they will modify. But I'm not, how much do the legs weigh, Dr. Scott? That's something you ought to know.

I was going to say, hell. How much? About a third of your body weight, I would guess. Amputated legs weigh. Well, a lot of your fat is in the, you know, gut, though. You have your muscles, but the largest muscles in your body really quads. Okay, above the knee prosthetic, though. Now that's the prosthetic is eight pounds.

Let's see, your advanced prosthetic. Okay. So what is the BMI of an amputee? The true weight of amputees, you know, what would be the weight of my missing leg or arm? Right? and there are no stupid question. So this is a great question. So the weight of limb segments.

This is from, what is the name of this website itself? It's a prosthetic website for people who are amputees. This is from the Journal of Biomechanics. It says that a man's thigh weighs 14.6 pounds. And so if you do the foot and the, The leg and the thigh, that would be 1.3 plus 4.3 plus 14.6. So was that 18, 19, 20 pounds. 20 pounds.

That's if they weigh 200 pounds. Right. And so that's two of them would be 40 pounds. So one of the reasons that they're able to do pull-ups is because they're 40 pounds lower. But they've also jacked up their upper limbs because they do all the work now. Yeah, one of my best friends growing up, his mama had been in a wheelchair for years, and she used to arm wrestle us when we were kids because we all thought we were big and strong, and she wore us out.

Yeah, there you go. That was great, yeah. So a man below the knee amputee with three quarters of the leg amputated, what they do is they add up the weight of the foot, which is 1.37 pounds, and three quarters of the leg. So it would be 0.75 times 4.33, and then that would be. 4.62. That's pretty interesting, isn't it?

Cool. Yeah. You've got one more bonus question. Okay. Yeah, so a man weighing 165 pounds will lose 7.62 pounds following a three-quartered leg

below the knee amputation. Are these percentages or are these pounds? Well, those are their weights? Okay, yeah. So a BMI calculation for amputees would be the true body weight

let me see oh okay so they have to calculate their true body weights what they do is they add back the pounds that they had and then they get their BMI by calculating the true body weight divided by the height that they would have been had they not had that and that's how they do it and it's an estimate listen BMI sucks we all know that but if you have a BMI that says you're super obese you're somewhere in the right category. You are, you know, you're way too much. And there's things that we can do to help if you will let us help you if you want help. We have a whole lot of, you know,

if in FiniFat influencers that say that, you know, they'll, if they go to a new doctor, they bring in a card and say, I don't want to talk about my weight or the consequences of my weight, and that's fine. If I have somebody come into me and says, I don't want to treat my cancer, then I'll take care of them and I'll refer them to hospice

or whatever. It's a free country, but we have a whole bunch of dead fat influencers out there as well, you know, people who died much younger than they maybe needed to. So I am concerned about that trend. But anyway, so for those of you out there, we, you know, we love you. we will help you, and we will respect your boundaries if you don't want to talk about it. But I just always wonder why that is. I mean, I know they've been yelled at by doctors their whole lives saying, you know,

and attribute everything to their weight. I have the same thing with people who have cancer that the, you know, the oncologists and other people will attribute everything to their cancer, particularly fatigue, when it turns out, you know, about 50% of them have low testosterone. If they don't have prostate cancer, we can treat that, and they feel better. So I get that part of it. Not everything is attributable to your weight, but your weight is increasing your risk of all-cause mortality. That's a fact.

And we can help you if you want help. But, yeah, you've got to do it yourself in the end. All right. What was the question? The last one looks like a Gustav. Gustav. It is blue in color, which means it is a...

Well, that is a super chat. Super chat. Thank you. Thank you, Gustav. Thank you for the 199. Yes. Says, Dr. Steve, I take Flonase daily for congestion. Is that legit?

Well, it's legit if you have perennial rhinitis caused by, you know, allergens or whatever. And I take Flonase every day because if I don't, I end up sneezing and congested. And so if your congestion is caused by swelling of the turbinates, which are the sort of fluid sensitive tissues in the nose that swell up that cause nasal congestion, and they are steroid responsive, it's probably okay to take that every day. I was never a big fan of exposing people to steroids every day, but my understanding is, and talk to your ear, nose and throat person about it, that this stuff is not. systemically absorbed enough that it's causing people problems. So do you, what, what's your, now the other thing is, though, try Dr. Scott's CBD nasals.

And I think Flonase is great for most people. Some people, they get kind of dry nasal passages and they get too dry it out. So that would be the only thing. Then that's when you need your simply herbals and nasal spray. They are worried about long-term use of Flonase. They're worried about it. I want to see the data of, you know, where you can get side effects. Like Dr. Scott said, you can get no sores if it dries out.

Yeast infections. You know, does it increase the risk of cataracts because you're taking a steroid, brittle bones because you're taking a steroid, you know. So I'll tell you what, will you put that on the list for next time? And let's take a deep dive on the data and see if there's any good data that says one thing or another. Because I hear a lot of people saying, well, we're worried about the risk of these things. things. I want to know if there really is data that says that there are risk. I don't want to hear it may increase the risk. It either increases the risk or it doesn't. That doesn't mean

that it increases, you know, that you're saying it always, you know, it always causes it. But does it increase the risk or are you just worried that it might increase the risk? In that case, I call bullshit, although, you know, there's enough reason to not take steroid every day. But it is, you know, it's been over the counter. They don't tell people they can only buy a certain number of them. It doesn't necessarily mean anything either. But we will do a deep dive on the data, and next time we're here, which will be, it'll be two Wednesdays from now, right?

Not next Wednesday, but the Wednesday after we'll do one to get. at that Saturday show and you'll have to do another Saturday but we'll be off for a little bit. Right. Right?

That's right. I think it's right. So we'll have the answer then. Yes. Because I'm going to, I think that's, you know what? This affects me

and it's all about me. So I'm going to, by God, find out. And if maybe, hell, maybe that's causing me. Problem, I don't know.

We'll see. But my understanding is from the ear, nose and throat guys, they'll tell you, at least the ones that I've talked to that they don't feel

like it's absorbed systemically enough into your bloodstream enough to cause that kind of problem but we'll see you don't agree with it well because he's selling his shit but it's not shit

Dr. Scott's stuff is little shit it's actually good all right well thanks always go to Dr. Scott Scott and thanks to everyone who's made the show happen over the years listen to our SiriusXM show on the Faction Talk channel SiriusXM Channel 103

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Until next time, check your stupid nuts for lumps. Quit smoking, get off your asses, get some exercise. We'll see you one week for the next edition of Weird Medicine. Thanks, everybody. Thank you, guys. Thank you.