Young and Profiting with Hala Taha - Dr. Chris Palmer: The Mental Health Discovery That Transforms How Entrepreneurs Perform | Mental Health | E402

Episode Date: June 8, 2026

Mental health care has a silent crisis, and Dr. Chris Palmer has spent 30 years watching patients exhaust medication after medication with little relief despite world-class treatment. His search for a...nswers became the foundation of his brain energy theory, a framework that proposes an entirely new way of understanding and treating mental illness. In this episode, Dr. Chris breaks down the science of mental health and metabolism, explaining how the brain's ability to produce and use energy may be at the root of psychiatric conditions. He also shares practical tips to support better brain health and overall wellness.  In this episode, Hala and Dr. Chris will discuss:  (00:00) Introduction (02:18) The Real Causes of Mental Illness (06:11) Accidental Discoveries in Medicine (11:35) How Bad Is the Mental Health Crisis? (23:04) How Metabolism Shapes Brain Health (29:48) The Brain Energy Theory (35:27) Too Much vs. Too Little Brain Energy (46:37) Delirium and the Brain Energy Theory (51:28) The Power of the Keto Diet for Better Health (01:03:50) Neurodivergence in Entrepreneurs (01:10:01) Advice for People Currently on Antidepressants (01:14:30) Habits to Optimize Your Mental Health  Dr. Chris Palmer is a psychiatrist and researcher at Harvard Medical School with over 30 years of clinical experience at McLean Hospital, one of the world’s top-ranked psychiatric institutions. He is the author of Brain Energy, which explores mental illness as a metabolic disorder of the brain. Through his clinical work, research, and public education, he is helping expand the conversation around mental health treatment, metabolic health, and lifestyle medicine.  Sponsored By: Indeed - Get a $75 sponsored job credit to boost your job's visibility at Indeed.com/profiting Shopify - Start your $1/month trial at Shopify.com/profiting. Quo - Run your business communications the smart way. Try Quo for free, plus get 20% off your first 6 months when you go to quo.com/profiting Remitly - Transfer money internationally across 100+ currencies with no hidden fees. Download the Remitly app or visit remitly.com to get started. Use code BUSINESS to get a $100 bonus after you send $300 or more. New customers only. Prolon - Reset your body with Prolon’s five-day plant-based program. Go to ProlonLife.com/PROFITING for 15% off sitewide plus a $40 bonus gift when you subscribe to their 5-Day Program. Northwest Registered Agent - Get a complete business identity with Northwest. Visit northwestregisteredagent.com/YAPFree and start using free resources to build something amazing.  Resources Mentioned: Dr. Chris's Book, Brain Energy: bit.ly/DrCP-BrainEnergy  Dr. Chris's Website: chrispalmermd.com  Active Deals - youngandprofiting.com/deals  Key YAP Links Reviews - ratethispodcast.com/yap YouTube - youtube.com/c/YoungandProfiting Newsletter - youngandprofiting.co/newsletter  LinkedIn - linkedin.com/in/htaha/ Instagram - instagram.com/yapwithhala/ Social + Podcast Services: yapmedia.com Transcripts - youngandprofiting.com/episodes-new  Entrepreneurship, Entrepreneurship Podcast, Business, Business Podcast, Self Improvement, Self-Improvement, Personal Development, Starting a Business, Strategy, Investing, Sales, Selling, Psychology, Productivity, Entrepreneurs, AI, Artificial Intelligence, Technology, Marketing, Negotiation, Money, Finance, Side Hustle, Startup, Mental Health, Career, Leadership, Mindset, Health, Growth Mindset, Biohacking, Motivation, Manifestation, Life Balance, Self-Healing, Positivity, Happiness, Sleep Learn more about your ad choices. Visit megaphone.fm/adchoices

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Starting point is 00:00:33 the podcast, a brand new series called How We Profit. Now, I've been doing Young and Profiting Podcasts for eight years, and my listeners are successful. We are real entrepreneurs with real businesses, and a lot of you guys are crushing it behind the scenes. You may not be super famous, you may not be a billionaire yet, but you've got a business that you've learned how to scale. And we want to hear from you. One of the best ways to learn as an entrepreneur is from your peers, and I found it super helpful to be in these peer entrepreneurship groups, and learn from other entrepreneurs who are at my level, but just in a different industry. So that's what I want to bring to this podcast.
Starting point is 00:01:10 I want this to be our own peer group, but on the podcast. And so I'm going to be interviewing people who are making anywhere from $500,000 to $10 million a year. They're not super famous. They're not the typical billionaires that are on my show. These are real entrepreneurs who are crushing it behind the scenes. And we're going to uncover what they do to sell, how they get their customers, what their profit margin looks like, how they market, and so much more. If this sounds like you and you want to be featured on Young and Profiting Podcast for our How We Profit
Starting point is 00:01:39 series, just head to younginprofiting.com slash apply and share your story. Let me know why you think you should be featured on the show. Again, that's young and profiting.com slash apply. And who knows, maybe you'll be our next guest on Young Improfiting Podcast. In any given year, about one billion people on the planet will be diagnosed with a mental disorder. Western countries like the United States, the rates are higher and have been higher for decades. Dr. Chris Palmer, a leading expert in metabolic psychiatry, he helps uncover the powerful connection between metabolism, brain health, and overall wellness. 93% of Americans right now have at least one biomarker of poor metabolic health.
Starting point is 00:02:23 A large study of millions of people looked at, of those who have obesity, are they at increased risk for developing a subsequent mental illness. And the answer was overwhelmingly yes. Something that was really surprising when I was reading your book is that when you have mental illness, it can actually shave off years of your life. On average, men are losing 10 years of life. Women are losing seven years of life. What are they dying of? It's heart attacks and strokes. What would you say to the listener right now who's on antidepressants? If you're taking an antidepressant and it has changed your life for the better, by all means, please keep taking it.
Starting point is 00:03:00 However, 90% of people taking antidepressants, that's not the case. So if you're having any of the side effects or it didn't really fully work for your symptoms, I would strongly encourage you first and foremost just... Hey, App fam, what if everything you've been told about mental health is only half the story? Today we're looking at mental health in a totally new lens. I'm sitting down with Dr. Chris Palmer, Harvard psychiatrist, researcher, and author of brain energy. His work is reshaping how we understand mental health, metabolism, mitochondria, and even the role a ketogenic diet may play in supporting brain health. And we'll explore all of this more deeply in the conversation.
Starting point is 00:03:42 But before we dive in, if this is your kind of podcast and you haven't followed us yet, this is your friendly reminder to follow Young and Profiting Podcast on your favorite platform and subscribe to our YouTube channel. It takes two seconds and it keeps you plugged into conversations that help you level up in every aspect of life. Now, Chris, welcome to Young and Profiting Podcast. Thank you, Hala, for having me. I'm excited for this conversation. We talk a lot about mental health on the podcast, but you're really bringing a new perspective to the table. And you've basically spent your whole career
Starting point is 00:04:13 trying to answer this one question, which is how does mental illness happen? Like, what is the cause of mental illness? And after all your research and all your time studying that, what did you come up with? So, you know, what's long been known is that there are a kind of myriad different causes of mental illness, and they often fall into three different buckets, biological, psychological, and social. And so we have this theory,
Starting point is 00:04:41 the biopsychosocial theory of mental illness, that there are lots of different things that can happen. And those include things like neurotransmitters, genetics, hormones, inflammation, sleep, drugs, and alcohol, but also psychological and social things like trauma, stress, adverse childhood experiences, those types of things. But precisely how they all fit together has perplexed people for millennia. And what I believe, based on the research I've done, is that we can actually begin to connect all of those things
Starting point is 00:05:19 through what we call metabolism. And that actually metabolic dysfunction or dysregulation can actually help us understand what causes mental illness. So it doesn't replace the biopsychosocial. It integrates the biopsychosocial. It puts it together once and for all. And I know that like traditional psychiatry really focuses, especially when it comes to like depression on this like chemical imbalance theory,
Starting point is 00:05:50 a lack of serotonin. What's the difference between or do you feel like that's still? accurate because you're saying like, you know, your theory kind of integrates with everything. Do you feel like that's accurate at all? Or do you feel like metabolism is really the key to all of that? I do think metabolism is key. So for people who don't know, the serotonin, like, hypothesis of depression largely is derived from the observation that medications like Prozac or Zoloft or Paxil, which all kind of inhibit the re-uptake of serotonin. So in other words, they increase the availability of serotonin in a synapse,
Starting point is 00:06:32 that those can work for depression. And there's no doubt. They really can work. And as a psychiatrist for over 30 years, I have seen them work time and again in different patients. And so the theory, that was really just a serendipitous observation, that these medications seem to help depression. And so the assumption was, well, patients with depression must not have enough serotonin.
Starting point is 00:06:58 That is really as simple as that. But in fact, we have decades of neuroscience research looking at serotonin levels in depressed people's brains. And it turns out they don't have lower levels of serotonin in their brains. So we actually have really robust, strong evidence. that people with depression do not, in fact, have a serotonin imbalance. Now, so that still begs the question, though, then why would these medicines work? And I actually believe that understanding the science of metabolism and more specifically, mitochondria can actually help us understand why they would work.
Starting point is 00:07:41 So serotonin is actually really important to brain metabolism and more specifically to mitochondrial function. And when you understand that, you can understand that it's not necessarily an imbalance of serotonin, and yet boosting serotonin for some people can be a really powerful treatment. Now, I definitely want to get into like what is metabolism, what is the role of the mitochondria, but first, like something that you said really piqued my interest because you said that basically this medicine, these antidepressants, they were used for other disease. And it was just like a side effect that they noticed that people were getting. getting happier, and then they just kind of leaned into that.
Starting point is 00:08:23 What is the problem with doing that in medicine? Because there's other instances of that. There's certain medicine where they realize it makes your eyelashes grow. And now everybody uses it for their eyelashes. And there's so many instances of like side effects turning into something that people use, which I just think is like a really strange way to go about prescribing medication. Unfortunately, that's actually more of the rule than the exception in the field. in the field of medicine.
Starting point is 00:08:50 You know, and this goes back to like the 1800s and before. It goes back to, you know, really ancient medicine. You know, ancient healers would find herbs that had medicinal properties. And they would grind these herbs or process them or dry them or do other things and give patients with certain symptoms or conditions these herbs. And sometimes these herbs actually really did work and they really can treat things like heart failure. The people had no clue how or why they were.
Starting point is 00:09:31 They just knew, oh, here's a plant. If we grind it up in a certain way and give it to people with these different conditions, it can be helpful. I mean, ancient Chinese medicine is all based on that. It's based on different things, like even acupuncture, there are theories about why if we place the needles in these locations,
Starting point is 00:09:49 do we see symptom reduction? Whereas we place the needles in other locations, it doesn't seem to work as well. So that's really the way most of medicine actually has developed is serendipitous observations. That if we give this medicine or if we give this plant or this substance to people, it can be helpful.
Starting point is 00:10:14 It can reduce symptoms. even though we had no clue how or why it worked. Like, we were using opioids like heroin and other opiates for pain relief for, again, centuries without really understanding how or why it works. So same too in the mental health field, as you mentioned. Like the first antidepressant was actually a tuberculosis treatment. And the people in the tuberculosis wards
Starting point is 00:10:45 were giving these people this treatment, but noticing that some of them had had pre-existing depression, and all of a sudden they were happier. And they're like, wow, I wonder if this would help those patients over on that psych ward, and maybe it would help them too.
Starting point is 00:11:01 And sure enough, they did. They didn't know how or why they worked. The assumption wasn't that people with depression also had tuberculosis. The assumption was that tuberculosis medicine is somehow doing something. Like even some of the health hair loss medications that men take.
Starting point is 00:11:18 That was serendipitous. They were blood pressure medicines initially and that, oh, wow, men are growing hair. Let's use it as a hair loss kind of method instead. Yeah. Unfortunately, it is unsettling because you would think that in 2026, we have a lot more science and rigor. But unfortunately, and we're getting there. We're definitely getting there.
Starting point is 00:11:42 And I don't want to discount all of the progress that we've had in. neuroscience and biological sciences and healthcare. And we are getting there to the point where if we understand, you know, certain receptors play a role in a disease, we can design medications to target those receptors and get the effects we want. You know, people are modulating the immune system in complex ways to help cure cancer sometimes. So medical progress is phenomenal, but still the bulk of medicine is based on these serendipitous findings.
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Starting point is 00:16:05 Mental health in this field of mental health within medicine, I feel like is relatively new compared to other fields within medicine. and more and more, you know, mental health seems to be a problem, especially with the youth, right? Like we always see these stats of, you know, whether it's 30% of adults have depression or whatever it is. There's all these stats always about how bad mental health is. Can you set the stage in terms of how we give a problem this is? And then also, like, is this getting worse or are we just diagnosing it now because it's something that we actually look at? Yeah, both really important questions.
Starting point is 00:16:43 The latest broad-scale epidemiological data that we have across the world suggests that in any given year, about one billion people on the planet will be diagnosed with a mental disorder. That represents about 13% of the world's population. In Western countries like the United States, the rates are higher and have been higher for decades. And it's about 20% of people in any given year will be done. diagnosed with a mental disorder. The lifetime statistics are much higher. So in the United States and other Western countries, about one in two people, 50% of all people will meet criteria for a mental illness at some point or another during their life. Now, sometimes the cause of these
Starting point is 00:17:36 mental health conditions is really obvious. It's, you know, a man who's married for 25 years, gets a divorce, loses custody of his children, loses, like, all of his livelihood and everything. It's obvious why he would develop major depression, and it would definitely last probably more than two weeks. And so he would end up meeting criteria for a mental illness. major depression. And he might get prescribed medications. He might be going to his primary care doc and that person would prescribe him an antidepressant or sleeping medicine or other things. So sometimes the cause of the mental illness is really clear and apparent and obvious. It's not some complex problem or issue to understand. Whereas other people have very complicated brain
Starting point is 00:18:35 conditions, whether they're neurodevelopmental like autism or ADHD, whether it's bipolar disorder, schizophrenia, or the person who gets severe crippling depression for no reason, for no reason at all. And everything else under the sun. So mental disorders include things like alcoholism, anorexia nervosa, you know, bulimia, includes things like dementia, Alzheimer's disease and others. So there's a broad, broad range of mental disorders. And the overwhelming preponderance of evidence strongly suggests the rates are increasing across the board, across a wide range of diagnoses. Now, there is debate and disagreement about that. Some will argue, as you suggested, that we're just better at recognizing it.
Starting point is 00:19:27 All these celebrities are coming out talking about their struggle with mental illness, and that's empowering. and encouraging people to talk about it. No doubt that that is all that's true, and that does affect the statistics somewhat. But that is not at all the entire explanation. I mean, rates of autism in the last 25 years have more than actually now quintupled. I used to have to say quadrupled,
Starting point is 00:19:56 but now it's quintupled. And yes, we're better at diagnosing it and recognizing it, but the rates are also. so legitimately increasing. Talk to us about the correlation between physical health, like people becoming more obese and having diabetes, with an increase in mental health diagnosis. Yeah, it's a great question and very much aligned with a lot of my research.
Starting point is 00:20:23 So everybody knows, in case you've been living under Iraq, obesity and diabetes are skyrocketing, skyrocketing and prevalence. 70% of United States adults are now overweight or obese. That is a black and white issue. It's not that we changed our definitions of obesity. It's not that people are screening more for obesity, so we're recognizing it more. It's obvious.
Starting point is 00:20:50 You can just look at photos from people in the 1950s on the street and photos from people on the street today, and you will see it with your own eyes. And what I would argue is that is related to mental health too. That at the same time that people are developing these metabolic disorders, so too will the rates of mental disorders increase or even skyrocket. And we have very strong data to support this. Most of that data is correlational, meaning, so for example,
Starting point is 00:21:31 A large study of millions of people looked at, of those who have obesity, are they at increased risk for developing a subsequent mental illness? And the answer was overwhelmingly yes. Anywhere from 50% more likely to 350% increased risk. And what were the diagnoses? Like a lot of people might think, well, maybe depression because of fat shaming. Sure? Yes, depression. Fat shaming might play a role, but also anxiety disorders, schizophrenia, bipolar disorder, eating disorders, somatoform disorders, personality disorders, were a dramatically increased risk. And that's after the person already had obesity. So what does that mean?
Starting point is 00:22:24 It means that if a child is developing obesity, that child is at increased risk for how having a mental illness in his or her future. Wow. It just makes me think because there's so much like, you know, body positivity around being overweight. And this gives it another lens that like there's more than just a vanity factor. It is actually impacting and can impact your mental health. And I think that's just something really interesting to realize that it's not just vanity.
Starting point is 00:22:56 It's not just looking good in clothes. It actually can impact your mental health being overweight. weight. I think that's a really important point. And by no means am I here to fat shame anyone? Of course. By no means am I here to make anybody feel bad about themselves or have lower self-esteem, but I think it is negligent for us to just assume that obesity is okay. And obesity is just, you know, it's just a way of being. It's a healthy choice. It's just another choice. It's another option. No, it is not. It is a serious, severe health condition that affects numerous parts of your body and your brain. And we should take that seriously. And we should do everything we can to try to prevent and address obesity.
Starting point is 00:23:46 Why? Not because I'm hyper about discipline and shaming people, but because I'm trying to improve people's lives. and I don't want them to suffer. Like when people have a chronic mental illness, for some of them, it can be a living hell. It really can. And it's much more complicated than just fat shaming in societal norms. Yes, they play a role, but it's so much more than that. And if we're really going to improve human health
Starting point is 00:24:18 and improve people's lives, we need to take this seriously. Something that was really surprising when I was reading your book is that when you have mental illness, it can actually shave off years of your life. You live a shorter life. Can you talk to us about that? Yeah, we've long known that people with severe chronic mental illnesses
Starting point is 00:24:40 like chronic depression, bipolar disorder, and schizophrenia, they lose anywhere from seven to 30 years of life, depending on what study you look at and what population. But a very large study published in one of the leading medical journals, not even psychiatry journals, but medical journals, found that it's almost across the board, all of the mental illnesses listed in DSM. So all of them are associated with premature mortality. On average, men are losing 10 years of life. Women are losing seven years of life. What are they dying of? Everybody always immediately goes to suicide. Oh, those mentally ill
Starting point is 00:25:19 people must be killing themselves, and that's why. Well, yes, it is true that people with mental illness are more likely to take their life. And if a 20-year-old commits suicide, that is going to skew the statistic down in terms of the average age of death. But that is not at all the primary cause of death. The primary cause of death in the mentally ill is the same that it is in everyone else.
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Starting point is 00:29:03 Let's get into the science behind everything. I want to start off with some definitions. Can you first help us understand what is metabolism? So a lot of people have kind of a simplistic notion of metabolism. They think that, you know, the probably more common or the more popular kind of definition is it's burning calories. because we think about it as it relates to our weight. And if you're burning a lot of calories, then you can have a quote unquote fast metabolism.
Starting point is 00:29:30 And these are the people who can eat anything they want, anything in sight, and they never gain any weight. And they must just be burning through it. And then there are people purportedly who have a slow metabolism and they're not burning calories and they can eat salads once a day. And they're gaining five pounds a week because their metabolism is just so slow,
Starting point is 00:29:53 no matter what they do, they can't lose weight. So burning calories is absolutely part of metabolism and is a critical part of metabolism, but metabolism is so much more than that. So I would offer this kind of relatively overview definition, which is metabolism is the process of taking food, water, oxygen, and turning it into energy. or building blocks that are used to make cells or make hormones or make neurotransmitters
Starting point is 00:30:29 or create bone or anything. So essentially, when we eat food, it gets turned into one of two things. It either gets turned into our actual body, different cells or cell parts, or it gets turned into energy that gets burned for fuel to keep us alive. And then metabolism also involves kind of the waste management process of that. Because when managing the waste products becomes dysregulated, that can back up metabolism, so to speak, and you can have a metabolic problem because you can't get rid of certain things.
Starting point is 00:31:07 So it's that. In a way, metabolism is fundamental to the definition of living organisms. So for example, viruses, cannot do metabolism on their own. And so most biological authorities will say viruses are not living organisms because they have to take over the metabolism machinery of a living organism. And so in that way, metabolism is huge, massive,
Starting point is 00:31:41 and it impacts essentially every aspect of human health. And so I know that an important part of metabolism, is the mitochondria, and we all learned in science class that it's like the powerhouse of the cell, right? But you call it the motherboard of the cell. So talk to us about what the mitochondria does, how it's related to metabolism, and then how this all connects to mental health. Like when I describe metabolism is this like overarching thing fundamental to living organisms, and it's ridiculously complicated. There are thousands of different hormones and molecules and everything circulating around
Starting point is 00:32:19 that contribute to metabolism, when people ask, well, what controls metabolism in the human body? It's actually not what most people would say. Like a lot of people might say the brain controls metabolism. And it's like, well, yeah, the brain plays a role in it, but it doesn't actually control metabolism in every cell and organ and tissue and stuff. And so the real answer, based on 2026 science,
Starting point is 00:32:47 The real answer, or the most likely answer, is that mitochondria are actually regulating and controlling metabolism throughout the body. And although they are in specific cells, like they, so as you said, they are the powerhouse of the cell. And what does that mean for those of you who want the refresher from your seventh grade biology class? What does powerhouse mean? It means that they are taking your food and oxygen and turning it into ATP, and that's kind of the energy currency of the cell. And so that's the powerhouse function. They're taking food and oxygen and converting it or transforming it into energy. And there's no doubt mitochondria do that, and that is critical to living organisms.
Starting point is 00:33:37 It's critical to human health. but cutting edge research over the last 25 years has actually completely shattered that simplistic definition. Mitochondria are so much more than that. They play countless roles in the function of cells. And so related to mental health, some of the things that they do that are going to start to connect the dots, connect these biopsychosocial dots for us, is that mitochondria actually play a role in neurotransmitter synthesis and release and regulation. And so if you if you buy into the
Starting point is 00:34:19 argument, oh, like schizophrenia is due to an imbalance of dopamine or something, it still begs the question, well, what causes that imbalance in the first place? And increasingly the science, the neuroscience is pointing at mitochondrial dysfunction or dysregulation. as the cause of neurotransmitter imbalances. But mitochondria do so much more than that. They play a role in epigenetics, which is the expression of genes from the cell nucleus. They play a role in inflammation,
Starting point is 00:34:56 turning it both on and off, and yet inflammation affects their function. They play a role in how hungry we are and how much energy we have. But here's the thing. Trauma. social adversity, stress, impact their function as well. They, drugs and alcohol do, and hormones do.
Starting point is 00:35:20 And actually, mitochondria control the first step in the synthesis of some key hormones that are known to play a powerful role in mental illness. And those include cortisol, estrogen, testosterone, and progesterone. And so if somebody has dysregulation of those hormones, you have to implicate mitochondria in that dysregulation. And so the title of your book that you put out a few years ago is called Brain Energy. And you kind of saw this as the red thread between like all mental illness, right? Like that everything was kind of interconnected when everybody thought that they were all from like different causes, basically.
Starting point is 00:36:02 But you say all different types of mental illness from ADHD to depression to schizophrenia to, to Alzheimer's, are all connected through this concept of brain energy. Can you distill that for us? We know that there are biological, psychological, and social factors that play a role. And I'm here to say yes, yes, yes, yes. We have decades of evidence to support that. But how are they connected? How exactly are they connected precisely in biology and physiology?
Starting point is 00:36:32 Like, how can we understand it? I think I deserve some credit for connecting some of these dots, but I certainly did not do a lot of this foundational research. So it's like hundreds, maybe thousands, of brilliant scientists and biologists and others have been working on this for decades. And I think the hopeful thing is all of their work once and for all is finally starting to culminate in better understanding.
Starting point is 00:37:03 standing mitochondria, all of the different roles they play. And that, when you look at that science, it begins to help us connect the dots of the mental health field, this biopsychosocial thing, and how does it all impact? The beautiful thing about it is that it kind of aligns with so many other things that we already know. People with mental illness are more likely to get physical illnesses. People with physical illnesses are more likely to get mental illnesses. It helps us understand how and why those are connected. And then maybe most importantly, it gives us a wide range of new treatment strategies that we might not be using right now to help people improve their not just mental health, but also their physical health simultaneously.
Starting point is 00:38:01 Something that I thought was really fascinating is this fact that your brain actually uses a lot more energy than you'd think. I know that my mom, for the longest time, whenever I'd be studying, she's like, make sure you eat because your brain takes up so much energy. And I'd be like, what are you talking about? Like, my brain's not burning that much energy. But I think in your book, you mentioned it, the brain makes up only 2% of body mass, but uses 20% of the body's energy. So talk to us about why that's so important to understand when we're talking about mitochondria and energy and, you know, not having enough energy created through your mitochondria leading to having mental illness or too much or too little. It goes both ways, actually. It does go both ways. And so, yeah, but no, it's a really important point that the brain is, the brain is like an incredible amazing. awe-inspiring organ.
Starting point is 00:38:59 It is really truly incredible. And for those who believe in God, you just, you know, it's only God could come up with something like the brain. It is incredible. But it is this incredible machine that does so many things for human life, human existence.
Starting point is 00:39:22 And it is like a supercomputer. and as such, it does require a lot of energy to function. And that level of energy production and regulation of that energy really is very similar to like a complicated supercomputer. So for those who are familiar with complicated supercomputers, it's actually the flow of energy that in part is making that supercomputer run. And you can burn fry circuits. If you put too much energy through them, and if you're not putting enough energy through them, then it's not going to work.
Starting point is 00:39:59 Well, guess what? Same thing happens in the brain. If there's too much or too little energy flowing in the right place at the right time, you're going to get dysfunction in those brain circuits. And at its core, that is one relatively straightforward easy way to understand kind of this theory. is that energy dysregulation or metabolic dysregulation can help us understand dysregulation in the functions of the brain, the myriad functions of the brain,
Starting point is 00:40:36 and when those functions become dysfunctional or don't operate properly, essentially that's what we call mental illness. Sometimes we call it a neurological illness when it's extreme and we can measure it, like a seizure or something like that. But in the mental health category, there aren't necessarily objective measures that we've developed today in 2026. And so we rely on symptoms and patient reports.
Starting point is 00:41:04 But when a patient says, I'm hearing something that's not there, we can assume that some brain networks are dysfunctional. And brain energy metabolism can help us understand how and why those brain circuits. can become dysfunctional. So let's talk about, like, we were just saying how energy, you can have either too much energy, too little energy, happening with our mitochondria and our brain, which results into different mental illnesses. So talk to us about when there's too much energy happening
Starting point is 00:41:38 and what happens in terms of like what kind of mental illness. And then what are the environmental factors that play along with having too much energy going through your mitochondria? So it really, I mean, it starts to get complicated fast. I just want to say that. For any of the neuroscientists listening, I fully understand this is really complicated. But I'm going to speak to a lay audience and try to make it sound simple. It's not simple.
Starting point is 00:42:06 And I'm sure my questions aren't that great because I'm not a neuroscientist. I'm like trying my best. Your questions are phenomenal. And these, and they're really important questions. So, but the way to simplify it is too much energy. sometimes can be represented by what's called hyper-excitability or overactivity of a network. And so a couple of clear examples of that. So somebody who has an anxiety disorder. What's the definition of anxiety disorder? Somebody who gets anxious for no good reason.
Starting point is 00:42:37 They can be sitting in their lazy boy recliner watching a really nice show, not thinking about anything, anxiety-provoking, and then out of the blue have a panic attack. And how do we think about that? The way I think about that is that their anxiety circuits in their brain became hyper-excitable. So they started firing when they shouldn't. And that is going to be associated
Starting point is 00:43:05 with more energy flowing through those circuits. But it results in hyperactivity of those brain circuits. Same thing can happen with OCD, but it can also happen with psychosis and with all sorts of other mental illnesses. One of the clearest examples of too much energy in the brain is for something called hypomania or mania, which is kind of one of the parts of bipolar disorder where people can get really hyper agitated, excited. Sometimes they feel euphoric. Other times they just feel really
Starting point is 00:43:42 irritable and nasty, but they are revved up. It's kind of the opposite of depression. They can feel great, they're going a mile a minute, they're talking a mile a minute, they might not even be sleeping because this energy metabolism is just like flowing through their brains. And we actually have a lot of evidence that their brains are overactive and energy metabolism is overactive. That's so interesting. And so a lot of people think this is mostly genetic, right? When people have these types of disorders, people really think it's genetic. Are there environmental factors that cause the increase of energy and like your metabolism being too crazy that are leading to these things?
Starting point is 00:44:27 100%. So again, and this I'll bring back to just some common sense, obvious observations. Obesity is, in fact, a metabolic disorder. Do genetics contribute to obesity? Yes, in some cases they do. but the primary cause of obesity is not genetics. Because 100 years ago, very few people had obesity. And we pretty much have the same genes that we had 100 years ago.
Starting point is 00:45:00 And so there's something in our environment that is driving obesity. And it's not just gluttony and poor willpower and, oh, everybody just can't resist delicious food. Believe it or not, they had delicious food 100 years ago. And people didn't get obese. They had chocolate chip cookies. They had pumpkin pie and apple pie. They had delicious foods 100 years ago, but people were not becoming obese. And so what is it?
Starting point is 00:45:31 And I would argue that it is dysregulation of metabolism, that there are things in ultra-processed foods, some of the chemicals and other things in ultra-processed foods that probably are very harmful to our metabolism, but there are things like environmental toxins, microplastics and other things accumulating in the human body that are probably harmful to our metabolism, but there are psychological and social things. So one of the clearest examples, to keep it focused on both mental and metabolic,
Starting point is 00:46:06 is this concept of adverse childhood experiences or ACEs. We've long known, And so these are children who have parents with mental illness, parents in prison, parents who are criminals, parents who are divorced, abuse, sexual abuse, neglect, poverty, loneliness, trauma. All of these things, all of these things are adverse childhood experiences. and what we know is that people who have a lot of adverse childhood experiences, the more you have, the more likely you are to have a mental illness. Exactly what mental illness, post-traumatic stress disorder, sure, but it's actually all of the mental illnesses.
Starting point is 00:46:56 It's depression, anxiety, bipolar, schizophrenia. It's also eating disorders and personality disorders and alcoholism and opioid addiction. and it's all of the mental disorders. But guess what? The very first studies of adverse childhood experiences, they actually weren't focused on mental health. They were focused on obesity. They were obesity studies.
Starting point is 00:47:23 The researchers were trying to understand why are some adults more likely to become obese than others? And they studied these adverse childhood experiences and saw strong correlations between the more adverse childhood experiences someone has, the more likely they are to be obese today. The more likely they are to have type 2 diabetes today, the more likely they are to have cardiovascular disease today, and the more likely they are to die early deaths.
Starting point is 00:47:57 And so we know that psychological and social factors impact, mitochondrial function, they also impact mental health, and they also impact metabolic health. So I'm here to say it's 2026, we have the science. We have more than enough science to connect these dots. So let's connect them and let's help improve human health. Yeah. And it's the stuff that you're saying sounds scary, but it's actually really positive because now that we know this, we can do something about it. So I definitely want to talk about all the things that we can do to improve our mitochondrial health. But before we do that, I want to talk about, I just want to get a few basics down in terms of
Starting point is 00:48:45 what happens to our brain when too little energy is being produced from our mitochondria. Like what are the things that happen to our brain when that happens? A simplistic way to put it. So for the neuroscientist, I apologize. I don't think we have many neuroscientists listening. A simple way, all of the neuroscience and, you know, entrepreneurs who are starting up their businesses, take this with a grain of salt because I know it's more complex in this, but a simple way to think about it is really obvious and it's true.
Starting point is 00:49:21 So although I'm simplifying it, it's very much true. If your brain doesn't have enough energy, it's not going to work right. It's really obvious and simple in that way. Do we have evidence that the brains of people with mental illness don't have enough energy? We do. We have an abundance of data. Decades of neuroscience research, decades of spec scans and pet scans and functional MRI and all sorts of things.
Starting point is 00:49:48 We also do have evidence that people with epilepsy, they don't have enough energy in their brains. People with Alzheimer's disease, they don't have enough energy. With Alzheimer's disease, the evidence is overwhelming and competitive. telling so much so that some people are now calling Alzheimer's disease type 3 diabetes are diabetes of the brain, which means that their brains aren't able to use glucose effectively as an energy source. And so their brains become underactive. They don't have enough energy. And if your brain doesn't have enough energy slowly, but surely, it starts to
Starting point is 00:50:28 atrophy or shrink, and if left unchecked, brain cells can begin to die. And that is actually what the process of Alzheimer's disease is, is brain tissue shrinking and potentially eventually dying off. And then people slowly but surely lose not just their memory, but all sorts of other brain functions, the ability to function in the world, the ability to walk, the ability to hold your bladder, like all of those things. And now alcohol and marijuana, that is slowing down energy production in your brain, correct? Like there's certain environmental factors that we're doing that can increase the slowing down of energy being created in your brain. Is that correct? 100%. Both of them are known to be toxic to mitochondrial.
Starting point is 00:51:24 function and health. Both of them are known to interfere with brain energy metabolism and ATP production. And both of them are known to, if you use too much of both of them, both of them, either of them, can increase risk for not just mental illnesses, a broad range of mental illnesses, depression, anxiety, bipolar disorder, schizophrenia, but also metabolic illnesses. People who use a lot of drugs and alcohol are often dying. And what are they dying? They're dying early deaths.
Starting point is 00:52:07 And what do they usually die of heart attacks and strokes? They're not dying of anything that unusual. Sometimes they're dying of liver cirrhosis with alcoholism or other things. So yeah, sometimes it's a little different than everyone else. But the most common cause of death in people with substance use disorders is still cardiovascular disease, hands down. It's just happening much earlier in life. One of the biggest, like, proof points for your theory of brain energy and how it impacts mental health is delirium and the fact that delirium exists. So talk just about what delirium is and how it sort of proves your point in all of this.
Starting point is 00:52:49 So that was, you know, as I was doing this research and doing this work, I honestly was always kind of checking myself and saying this can't possibly be true. It can't possibly be, it's really complicated, but in my mind it was becoming so much clearer and more simple. And I was even kind of, I was very skeptical of my own kind of theory or hypothesis. And I was like, it can't be this simple. And so I I actually was looking for opportunities to, like, well, if it's really true, what would help me prove this? Like, let me take a far-fetched example, maybe even unrelated to what most people think of as mental illness, and see if this lines up, like see if this hypothesis lines up. And delirium was one of the clear ones. And so what is delirium? Delirium can be, it's basically an acute change in mental states.
Starting point is 00:53:49 And what does that mean? It means that somebody who is otherwise healthy or even unhealthy all of a sudden has an abrupt change in their mental health. They start hallucinating. They get severely depressed. They get really agitated. They develop new onset OCD like overnight. And what are the symptoms of delirium? It's essentially anything that you can think of that's related to mental health. Anything related to mental health can happen. with delirium, even, shockingly, things like eating disorders or substance use disorders or other things. People who are delirious might start over-drinking alcohol because they're just so out of it. They're so confused. They're so disoriented. And that's part of delirium as well, as people often are, at least intermittently, really confused. And you ask them, where are you right now and they may not know? you ask them what year is it, they may not know, or they might say, oh, it's 1978. And you're like, oh, no, no, it's not. And it's like, oh, yeah, it's 1978. And you're like, okay, that's not a good sign. Something's wrong with your brain. And then if we look at, well, what exactly can cause delirium?
Starting point is 00:55:08 That's where I believe we see at least support for the brain energy theory, which is anything that can disrupt or dysregulate metabolism can cause delirium. So a lack of oxygen. So what is oxygen primarily used for in the human body? It's primarily and abundantly used by mitochondria for metabolism or energy production. That is why we have to breathe in and breathe out. And when we breathe out, what are we breathing out? We're breathing out carbon dioxide and where does that come from? that's a waste product of metabolism. So that's how to, I mean, that's how foundational metabolism is to human health. And if you deprive people of oxygen, whether it's suffocation, whether it's asthma or pneumonia,
Starting point is 00:56:02 whether it's just being at a really high altitude and being vulnerable and sick, when you deprive people of oxygen, you can see them get delirious. and so you can see them all of a sudden begin to develop any or all of the signs or symptoms of mental illness. But then I was also looking at what else can make people delirious, like a broad range of medical conditions, toxins, medication overdoses, all sorts of things can make people delirious. But in my mind, if you then look at all of those different things and kind of ask, yourself the question, do they converge anywhere? Do all of these different things converge anywhere?
Starting point is 00:56:50 I would argue, yes, they converge at the level of mitochondria and metabolism. And why is that? It's because metabolism is so important to human physiology. So it's not like it's this mysterious, ironic thing. It's metabolism is the elephant in the room when it comes to human health. And so, of course, it's going to affect the elephant in the room. How could it not? Why would it. But let's open our eyes to the elephant in the room and start paying more attention to the elephant in the room. And we need to understand how we can make it the healthiest elephant in the room possible. So let's move on to like solutions, like what we're supposed to do. So you had this really awesome case study. You treated a 33-year-old patient who had schizophrenia named Tom.
Starting point is 00:57:38 And he had hallucinations and delusions for 13 years. He tried 17 different medications. and you originally suggested that he go on a keto diet to lose weight and, you know, he had a lot more happen to him. So talk to us about this case, what it unlocked for you, what you learned, and what we can learn from it. So it's really interesting because this particular patient had, he'd been my patient for about eight years at that point. And he had tried so many traditional treatments. He was being treated at McLean Hospital and Harvard Medical School, where I work, which is one of the top-ranked psychiatric hospitals in the world. He had been in and out of the hospital, in and out of residential
Starting point is 00:58:26 treatment programs and other things. So he was getting the best care possible. And even for people who want to say, Dr. Palmer, you suck. You're not a good doctor. He was getting treatment from other people. And even with the best of the best care, he was profoundly ill and just tormented by his symptoms. And so when I prescribed the ketogenic diet, within a couple of weeks, he was not only losing weight, but I was noticing like this dramatic antidepressant effect in him. And he was just making and better eye contact and smiling more and talking more. I was initially like a little bit surprised. I'm like, what's gotten into you?
Starting point is 00:59:12 Like, why are you so happy all of a sudden? And like, what's going on? And it wasn't just that he was happy about losing weight. It was, like, profound. And he was, like, talking about all sorts of things that he had never really talked about. The thing that really upended my career and really changed the trajectory of my career
Starting point is 00:59:29 was it was about two months in, so it didn't happen overnight. But about two months in, he actually started telling me that my hallucinations are going away, my delusions are going away. He was like, you know, Dr. Palmer,
Starting point is 00:59:43 how I think there are all these families torturing me and targeting me and they have technology that can control my thoughts and all that stuff. And initially I was like, oh, yeah, we've talked about that a million times or we got to talk about that again.
Starting point is 00:59:56 And then he was like, I actually, now that I'm saying, it, I don't think it's true. And maybe it never was. And maybe like everybody's been trying to tell me, I've had schizophrenia all along. And maybe my schizophrenia is going away. That man went on to lose now over 160 pounds
Starting point is 01:00:21 and has kept it off to this day 10 years later. That man was able to move out of his father. father's home, live independently for a while, like start doing things that he had not been able to do. And it honestly, it was truly just mind-blowing for me initially. And but it, I knew that I couldn't ignore it. Even though I was initially in disbelief myself, I was like, this can't be happening. What the hell? What the hell is this? But I, I knew I couldn't ignore it and that I somehow had kind of a moral or ethical obligation to try to understand it as best I could. And ultimately, that's what led to me doing the work that I do
Starting point is 01:01:16 today and have been doing for over 10 years. And it's ultimately what led to me developing this theory. And so what actually happened when you put them on the keto diet? Why is low carb? Why is the keto diet so amazing for mental health and not only just losing weight. You know, so the easiest place to start with that is, unbeknownst to most people who've heard of the keto diet for weight loss or a dangerous fad diet or the American Heart Association hates this diet and you're all going to die of a heart attack. Unbeknownst to all of those people, the ketogenic diet is actually a 100-year-old evidence-based treatment for epilepsy. It was not developed as a weight loss diet. It was actually developed to stop
Starting point is 01:02:08 seizures by a neurologist. And it is now an evidence-based treatment for epilepsy. It can stop seizures even when medications fail to work. And why is that important? It's really important because we use epilepsy treatments every day in psychiatry in tens of millions of people. Most of them are pills, but medications that are developed to stop seizures commonly work for conditions like schizophrenia or bipolar disorder or depression or anxiety or eating disorders or all sorts of things. And we actually know a tremendous amount about the science of how the ketogenic diet It does stop seizures. It changes neurotransmitters, reduces brain inflammation,
Starting point is 01:03:00 does all sorts of things. Central to my thesis, it improves mitochondrial health as well. So it improves metabolic health, mitochondrial health. And is any of that relevant? So all of that is relevant to epilepsy. So if you ask the question, well, is any of that relevant to mental illness? It turns out all of it is relevant to mental illness. again, we have decades of science to prove that.
Starting point is 01:03:27 And so even that story, I was able to connect a lot of scientific dots. And I think that's why, you know, even I was able to get it published in prominent journals like schizophrenia research. Initially, I really was worried. Nobody's going to take this seriously. They're not going to publish this. People are going to laugh at me. I might get fired for my job.
Starting point is 01:03:52 Like, people are going to think I'm crazy. And so I went into it knowing that, knowing that everybody's going to be skeptical about this. Nobody's going to take it seriously. And the only chance I have of getting them to take it seriously is I have to understand the science. I have to understand why they should take this seriously. And do we have enough science? And I'm so grateful to all of the hundreds or thousands of research. who have been doing this work tirelessly for the last century,
Starting point is 01:04:26 because they put together this evidence base that I could tap into and use to advance this work. So it was really, they created the puzzle pieces, and I looked at those pieces of the puzzle and began to put them together in a coherent way. So, but I would have never been able to do it without all of their work. So with keto, just so we can understand it, like let's try to make this as action, as possible for our listeners. They're entrepreneurs, their high achievers listening in. They obviously want better physical health. They definitely want better mental health. They don't want to be burned out. They want to be able to focus. A lot of entrepreneurs have ADHD. That's for sure. How can we leverage
Starting point is 01:05:09 this knowledge of knowing that the keto diet can also improve our mitochondrial health? And like, what are some things that we can do to start aligning closer to the keto diet where it's not a diet where it's like more of a lifestyle? Yeah. It can. be. So I would say the first thing for any of your listeners who are wondering, could any of this apply to me personally, the first thing I would ask them to do is just assess their overall mental health and metabolic health. Like, do they have a mental health or a metabolic health problem? If they don't, then I would say, please keep doing what you're doing. And like, you're living the dream and good for you. And I really don't.
Starting point is 01:05:52 care what it is. If you're a vegan, if you're a vegetarian, if you're eating meat all day, like, I don't care what you're doing. It's clearly working well for you and just keep doing it. But to everybody else, and that's about 93% of your listeners, to everybody else, 93% of Americans right now have at least one biomarker of poor metabolic health. So that is, and there are only five basic biomarkers we're talking about. So that is abdominal obesity, high triglycerides, low HDL cholesterol, insulin resistance, and high blood pressure. Those are the five things. And 93% of Americans have one or more of those in the abnormal, unhealthy territory. So if you are one of those people and or you also have mental health symptoms, I think everything
Starting point is 01:06:53 we're talking about is highly relevant to you. And so the reason I bring up those biomarkers is because those can be helpful to help people understand, am I making progress? And so if you are overweight or obese, the simplest way to start this would not necessarily ketogenic diet. I would never stand in the way because it's a very good weight loss tool for a lot of people. So if you are open to doing ketogenic diet, go for it. But even if you're not, you could use other weight loss strategies to improve your health. You could start exercising more. So I would really rest strongly on the pillars of lifestyle medicine. So that's healthy diet nutrition, good sleep, avoiding harmful substances, having good relationships, stress reduction practices. I forget if I said exercise.
Starting point is 01:07:50 Exercise, I think, is the last one. So six pillars of lifestyle medicine. And I would say, try to optimize those. Try to optimize your diet. Try to optimize those other things. And how do you know if you're succeeding? If you're succeeding, if you're doing the right things, because I know you're getting conflicting advice. If you go on social media, you're going to get all sorts of conflicting advice about what's the right diet, what's the right exercise program. Marijuana, it's good for you. No, it's bad for you. Alcohol. Make sure you drink two drinks a day. No, don't drink anything. I get it. It's so confusing. What are we supposed to be doing? How do you know if you're doing the right thing? Your health is going to be improving. Your mental health is going to be improving.
Starting point is 01:08:34 Your physical health is going to be improving. Your metabolic health is going to be improving. And if it's not, don't say, woe is me. Don't say you're just getting older and you have slow metabolism. Don't make excuses. They're lame excuses. Find out what you need to do. And sometimes it's not just, you know, do it harder, be more disciplined. Sometimes you're just not following the right plan.
Starting point is 01:09:02 And so, you know, if you're in that situation, then maybe, move on from do it yourself. Because a lot of this people can do themselves. So please, by all means, do it yourself. And if it works, great. You've accomplished your goal. But if it doesn't work, please understand. There's a whole kind of army of healthcare professionals waiting to help you,
Starting point is 01:09:28 your primary care physician, health and wellness coaches, fitness trainers, so many dieticians, nutritionists, so many people want to help you. optimize your health. So get help, get support, get better advice, get better recommendations until you find the things that work for you. Now, let's move on to more of like entrepreneurship in general. So a lot of entrepreneurs, they wear some of their neurodivergence as like a badge of honor. Like they believe like ADHD is a superpower, which which can be. Like I feel like I have a bit of ADHD and it kind of really helps me in certain instances of my career. And even like we're like sometimes autism is worn with the badge of honor, especially if like you're on a, you know,
Starting point is 01:10:17 a spectrum where you can be productive, right? So what would you say to them? Would you say, is that an energy imbalance that we need to improve or like what would you say to somebody that is like proud of their ADHD? You know, even those two examples and they're a great example. And for anybody who's not really familiar with, like, the autism and entrepreneurship, some of the, actually, the wealthiest people in the world are probably on the spectrum. Some of them have openly disclosed that. Bill Gates has openly disclosed that. Elon Musk has openly disclosed that.
Starting point is 01:10:57 And there are many others. So some of the most brilliant people on the planet are on the spectrum. And in some ways, that's not surprising because we've long known that a select group of people with autism do have these kind of extraordinary cognitive abilities. And if they can capitalize on them and use them for good, then it's nothing short of amazing what they are able to accomplish. And I would never want to stand in the way of an Elon Musk or Bill. Bill Gates or someone else who's on a war path to change the world and improve the world economy and our lives and technology and everything else. Like, get out of their way and let them do their thing.
Starting point is 01:11:47 Why not? But at the same time, people who are on the autism spectrum, including those individuals, often suffer. even Elon Musk talks about his horrible childhood and a lot of the social adversity he experienced. He's had trouble maintaining relationships with wives. And does that matter? Yeah, it probably does matter.
Starting point is 01:12:17 And does it matter to him? It probably does matter to him. And so I do think, and I know he has self-medicated with substances and other things, and he actively talks about it, and sometimes he goes on talk shows and actively uses right there right on the talk show, so to leave no doubt. And so even for somebody extraordinarily successful, extraordinarily brilliant, extraordinarily wealthy and powerful, they can still suffer. And do I think that these strategies can be helpful for them? Yes, no doubt. Like, to answer your basic question, does brain energy metabolism apply
Starting point is 01:13:01 to ADHD and autism? 100% unequivocal, yes. The mitochondrial theory of autism was actually first proposed in 1985, 40 years ago. And so we've actually long known, and we have an abundance of scientific research linking brain energy metabolism or mitochondrial function with both ADHD and autism spectrum. So does that mean that if somebody sends me a person with profound autism, can I cure them of their autism? No, no, I can't. Because autism and ADHD on some levels are neurodevelopmental. And neurodevelopment is happening and then it sometimes becomes fixed. So we have neurodevelopmental windows or periods of time
Starting point is 01:13:58 during which people need to acquire certain skills and certain brain regions and brain cells and synaptic connections and other things need to happen. And if they don't happen kind of quote unquote neurotypically or if they don't happen neurotifically, then they can result in neurodivergence or neurodiversity. And sometimes those changes may not be reversible. And that person is going to have some of those traits long term. However, some of those things are still ongoing and some of those things are due to a brain
Starting point is 01:14:37 energy metabolism, dysregulation, and we can actively treat those symptoms and help reduce suffering and improve function in people. There's no doubt about it. I have a lot of patients who are on the spectrum, and these strategies can be extraordinarily powerful for at least some of them. I never say it all because I can't cure everybody or I can't dramatically improve the lives of everyone because not every treatment is going to work for every person. And so sometimes it starts getting complicated and we need to think about what treatment are we going to use,
Starting point is 01:15:16 are we going to use a medication, a dietary intervention, exercise, sleep, substance use treatment. Like, what are we going to do? And so it can get complicated fast. Nonetheless, there is no doubt in my mind. These strategies that I've outlined in brain energy can apply to people with a broad range of neurodevelopmental conditions, psychiatric conditions, neurodegenerative conditions. And I do think they can really change lives and improve lives.
Starting point is 01:15:50 What would you say to the listener right now who's on antidepressants? They're working with a provider who's prescribed them to them, never talk to them about this brain energy. theory, what would you tell them to do? I think the first thing I would just recognize, kind of like we talked about, that I do believe serotonin, for example, that's a big mechanism of action of some antidepressants, not all of them, that there's no doubt in my mind, it does play a role in energy metabolism and mitochondrial function. So I would say to that listener, if you're taking an antidepressant and it has changed your life for the better and you're so, you feel so much better on it,
Starting point is 01:16:29 off it, by all means, please keep taking it. If you're not having any side effects, congratulations. So if it has robustly worked for you and it's continuing to work for you and you're not really having side effects, I would say the easiest solution is just keep taking it. However, 90% of people taking antidepressants, that's not the case. So 90% of people taking antidepressants. It's kind of sort of working, but not really. It has side effects. I'm gaining weight. I have sexual dysfunction. I can't, I'm not really interested in sex anymore. It's slowing me down. I feel numb. I don't feel emotions like I used to. I don't feel like myself. So if you're having any of those side effects or it didn't really fully work for your symptoms,
Starting point is 01:17:27 I would strongly encourage you first and foremost just to get educated. So it could be read the book. It could be watch this, listen to this podcast and learn more about this and the strategies that we're doing. But there are so many free resources available. Even my book, you can get at a lot of libraries. So don't buy it. Just go.
Starting point is 01:17:49 If you don't want to, I'm not trying to sell you anything. I'm just trying to help you. If you don't want to buy it, go to the library and get a copy for two weeks. and read it. So there are lots of free things you can do to learn and get educated. But it's really about that is your baseline. Like understand what we're doing. Understand what your goals are.
Starting point is 01:18:11 Kind of understand the different aspects that you need to work on. So that person on an antidepressant, are they also overweight? Do they have diabetes? Are they pre-diabetic? Are they overeating comfort foods? Are they drinking too much? Are they smoking marijuana every night to relax? Do they sleep okay?
Starting point is 01:18:33 Are they exercising at all? And depending on your answers to those questions, I'm going to prescribe different interventions. And the interventions are obvious. It's not rocket science. You don't have to be a neuroscientist or a psychiatrist or even an entrepreneur to understand this. You just need to, like, the solutions,
Starting point is 01:18:55 are obvious based on the questions I ask. And if those things apply to you, then you can think about, well, which one do I want to try first? And then what am I going to do next? And one thing at a time. Some other people like to dive in and just do it all at once.
Starting point is 01:19:11 I don't care. It really doesn't matter to me. Just do something. Like try to improve your health. Because I do want to say, I just know that there are, literally hundreds of millions of people on this planet who are living suboptimal lives
Starting point is 01:19:36 because they do not have optimal mental and metabolic health. And it means that they feel brain fogged, unmotivated, uninterested in sex. those are the less concerning ones, all the way to I'm tormented by these voices, I'm tormented by my chronic depression and suicidality, I'm tormented by my OCD symptoms, I can't take it anymore. And I really honestly believe that this field, this science,
Starting point is 01:20:16 this research, these treatment strategies, offer new opportunities of hope and healing to all of these people. If you could distill down like three to five things that our listeners can do today to optimize their brain energy and their mental health, what would they be? I know you mentioned like, you know, exercise and things, but like what are more like specific things that we can do or things that we can replace like that you know, that common things that people typically do that we can do differently? So the first one that I am going to list, I know it's cliche and whatever, but you've got to optimize your diet.
Starting point is 01:20:54 Because if you are eating really kind of harmful, inflammatory, high glycemic foods every day throughout the day, it's going to be very challenging for you to do much more. So at a minimum, just what would I recommend? And if you're eating a lot of ultra-processed foods, take out junk food, try to eat more whole real foods. Try to cook some meals at home from scratch. Make a piece of salmon. You know, steam some vegetables. Cook a steak. Like make some eggs in the morning instead of the breakfast cereal.
Starting point is 01:21:43 whatever. So optimize your diet. The second thing I would probably recommend is optimize your sleep. One third of Americans aren't getting enough sleep. You need seven, eight hours of restful sleep every night. The probably the best biohack I have for sleep is go to bed earlier than you're currently going to bed. And why? Because I'm going to guess you're probably tired before you go to bed. And why do I say that? Because you're couch surfing Netflix or you're on your phone scrolling social media. And why are you doing that? Because you're burned out. You're tired. You're exhausted from a long day. You're stressed. You're trying to get all the stressful projects in your mind out of your mind. And guess what? If you fall asleep, they'll all be out of your mind. And that's your easy escape.
Starting point is 01:22:38 So go to bed early. The beautiful thing, if you're really go to bed super early, the beautiful thing is you might be able to start getting an adequate amount of sleep and waking up without an alarm. And I have to say that is one of the greatest gifts you can give yourself is to be able to wake up without an alarm. And why do I say without an alarm? Because an alarm by definition is disrupting how much sleep you need. Your body clearly needed more sleep. That's why it was still sleeping and you are disrupting that. So if you can let yourself get more sleep, that would be great. The third thing I would say probably is reduce harmful substance use.
Starting point is 01:23:19 So if you're over drinking, overusing marijuana, if you are vaping, if you're smoking, if you're smoking, please reduce those behaviors or stop doing those things. And fourth thing probably would be add in some exercise. I would actually put them in this order. Like diet, number one, sleep number two, harmful substance use reduction number three, and then throw in some exercise. And the exercise could start with as simple,
Starting point is 01:23:57 if you're really not doing much of anything, go for a walk around the block at the end of the day. Just, you know, maybe eat, your dinner, because you're going to try to get to bed early. So eat your dinner right when you get home and then go for a little walk, like a little 15 minute, 30 minute walk. If you have a partner, take your partner with you and that will build your relationship with your partner. You might just talk, chat with each other about how did your day go, honey? How was my day? What are you worried about? What are you stressed about? And that could go, that could be a huge.
Starting point is 01:24:35 huge life-changing, game-changing kind of routine that you could build into your day, and then you come home and you unwind, and then you try to get to bed early. I love that advice. Good, good concrete advice. Okay, last question to you. I want to respect your time. What is the opportunity for entrepreneurs who might want to get into this space or support people with their mental health? I think there are countless opportunities to entrepreneurs. So as you mentioned, it can start with your own personal health. Optimize your personal health. If you optimize your brain function, you're probably going to optimize your performance at work, your business strategies, your productivity, all of it. So if you optimize your health,
Starting point is 01:25:22 you may very well optimize your revenue streams and profit margins. Number two, look at doing this in your employees. Because if you can optimize their health, they will be more productive, they will be more resilient, they will be less likely to call in sick, they will be, have great ideas, they'll have greater motivation,
Starting point is 01:25:49 cognitive function. Trust me, an employee whose brain is running on all cylinders is going to be much more productive than your burned out fried employee after lunch who's surfing the internet whenever nobody's looking. And so that can be a way. And then for those who are really interested in the mental health or fitness or metabolic health space, there are countless business opportunities just to kind of capitalize on this science.
Starting point is 01:26:23 All the way to biotech companies, I've spoken with many pharmaceutical and biotech companies who are extraordinarily interested in this space. and the science and developing new products, new medications, new supplements, new things that can be used to help improve people's mental and metabolic health. So that could be a billion dollar product that you end up helping to develop. But if you're in the technology space, there are needs for AI assistance with how do we do this, how do we use all of this information, put it together. There are apps that could empower individuals to improve their mental and metabolic health.
Starting point is 01:27:08 I mean, the list goes on and on and on. You could think about incorporating this into gyms. You could think about incorporating this into restaurants. I mean, I'm really hard pressed to think of any one business in which this doesn't one way or another somehow apply. And so for those of you who are really interested in it, want to dig into this science, want to think about creative solutions. Again, there's a massive market opportunity. The world's health is abysmal right now. There's so much opportunity to capitalize on that and make money and in the process help other human beings.
Starting point is 01:27:51 So, like, win-win. I totally agree. Chris, this was such an awesome. interview. I end my show with one question I ask all of my guests. What would you say your secret to profiting in life as this can go beyond financial? So what is your secret of success? You know, I think the most important thing for me, but research bears this out, is relationships. So cultivating and paying attention to other human beings. And, you know, as a healer, physician, I'm particularly motivated to just help other human beings when they're down and out,
Starting point is 01:28:33 but it's truly just amazing how often those human beings then will step up for you when you need it and will reciprocate and even just the gratitude that they can express just, you know, fills my heart and keeps me going. I was talking to somebody recently who said, if you ever need to decide how to spend your money or your time, always choose relationships. And that's stuck with me. Chris, this was an awesome interview. Thank you so much for your time. Where can everybody learn more about you and everything that you do?
Starting point is 01:29:07 You could just go to chris palmermd.com. That's the easiest place. Chris Palmer MD.com. Amazing. We'll stick that link in the show notes. Chris, thank you again for joining us on Young and Profiting Podcast. Thank you so much. Yeah, fam, this was such a fascinating conversation.
Starting point is 01:29:24 with Dr. Chris Palmer. And I think one of the biggest shifts from today's episode is realizing that mental health and physical health are not separate. Your brain is a physical organ and it also runs on energy. And when your metabolism, sleep, nutrition, stress, or substance use are out of balance, your brain feels it too. One thing that really stood out to me was Dr. Chris's explanation that the brain is only 2% of our body weight, yet it uses 20% of our body's energy. That means burnout, brain fog, anxiety, lack of focus, and even emotional instability aren't always just personality traits or mindset problems. Sometimes your brain is under fueled, overstimulated, inflamed, or simply exhausted. And I think that's incredibly empowering because it means
Starting point is 01:30:08 there are practical things that we can do to improve the way that we think, feel, and perform. First, you got to start treating your lifestyle like it's part of your mental health strategy. Protect your sleep, move your body consistently, and cut back on ultra-processed foods, alcohol, and habits that drain your energy. Second, pay attention to your metabolic health. Now, not 10 years from now. Dr. Chris talked about how obesity, insulin resistance, and poor metabolic markers are strongly linked to future mental health challenges.
Starting point is 01:30:36 Your health is not just about how you look. It affects your focus, resilience, mood, and longevity. And finally, don't accept feeling terrible as your baseline. One of the most inspiring moments in this episode was hearing about a patient with severe schizophrenia, who transformed his life after improving his metabolic health. That story is a reminder that the brain can change, heal, and recover more than most people realize. And he did this all through a keto diet. Thanks so much for tuning into this episode of Young and Profiting Podcast. If you enjoyed this conversation with Dr. Chris Palmer, then spread the word and help others listen,
Starting point is 01:31:09 learn, and profit as well. And if you did enjoy this show and you want to thank us, then drop us a five-star review on Apple Podcast, Spotify, CastBox, wherever you listen to the show, nothing helps us reach more people better than a good review from you. If you prefer to watch your podcast as videos, you can find us on YouTube or Spotify video. Just look up Young and Profiting and you'll find all of our video episodes there. You can also find me on Instagram at Yap with Hala or LinkedIn by searching my name, Halataha. And finally, a huge thank you to my Yap team. You guys are all legends.
Starting point is 01:31:41 This is your host, Halataha, aka the podcast princess, signing off. Hey, Appam, we're about to launch something that might be my favorite thing we've ever done on the podcast, a brand new series called How We Profit. Now, I've been doing Young and Profiting Podcasts for eight years, and my listeners are successful. We are real entrepreneurs with real businesses, and a lot of you guys are crushing it behind the scenes. You may not be super famous, you may not be a billionaire yet, but you've got a business that you've learned how to scale. And we want to hear from you. One of the best ways to learn as an entrepreneur is from your peers. And I found it super helpful to be in these peer entrepreneurship groups and learn from other
Starting point is 01:32:24 entrepreneurs who are at my level, but just in a different industry. So that's what I want to bring to this podcast. I want this to be our own peer group, but on the podcast. And so I'm going to be interviewing people who are making anywhere from $500,000 to $10 million a year. They're not super famous. They're not the typical billionaires that are on my show. These are real entrepreneurs who are crushing it behind the business. scenes and we're going to uncover what they do to sell, how they get their customers, what their
Starting point is 01:32:50 profit margin looks like, how they market, and so much more. If this sounds like you and you want to be featured on Young and Profiting Podcast for our How We Profit Series, just head to younginprofiting.com slash apply and share your story. Let me know why you think you should be featured on the show. Again, that's young and profiting.com slash apply. And who knows, maybe you'll be our next guest on Young Improfiting Podcast. Hey, y'all. It's Kelly Clarkson with Wayfair. Ever order for furniture online and wonder what if? Like, what if it doesn't hold up?
Starting point is 01:33:18 That sofa was four days old. You should have ordered from Wayfair. With Wayfair, there's no what if. Just style you love and quality you can trust. Visit Wayfair.ca. Wayfair, every style, every home.

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